Dietetics and Clinical Nutrition Commons^™

Source-Specific Nitrate And Nitrite Intakes And Associations With Sociodemographic Factors In The Danish Diet Cancer And Health Cohort, Dorit W. Erichsen, Pratik Pokharel, Cecilie Kyrø, Jörg Schullehner, Liezhou Zhong, Catherine P. Bondonno, Frederik Dalgaard, Peter Hendriksen, Torben Sigsgaard, Jonathan M. Hodgson, Anja Olsen, Anne Tjønneland, Nicola P. Bondonno

Research outputs 2022 to 2026

Background: The dietary source and intake levels of nitrate and nitrite may govern its deleterious versus beneficial effects on human health. Existing evidence on detailed source-specific intake is limited. The objectives of this study were to assess nitrate and nitrite intakes from different dietary sources (plant-based foods, animal-based foods, and water), characterize the background diets of participants with low and high intakes, and investigate how sociodemographic and lifestyle factors associate with intake levels. Methods: In the Danish Diet, Cancer and Health Cohort, sociodemographic and lifestyle information was obtained from participants at enrolment (1993–1997). Source-dependent nitrate and nitrite intakes were calculated …

Impact Of Diet Culture On Disordered Eating Habits In College Students, Laura Vanderlinde Padgett

All Master's Theses

Eating Disorders (ED) impact people worldwide at increasing rates and are a contemporary public health issue in the United States. The purpose of this research was to understand if exposure to Diet Culture impacts disordered eating behaviors in college students. A cross-sectional study was conducted of adults aged 18 and older who were currently enrolled in at least one college-level course during the period of August 2023 to December 2023. Utilizing the platform Qualtrics, an anonymous survey was created and distributed via online and in-person sources. Researchers created 5 survey questions aimed at collecting data on the familiarity and exposure …

Factors Associated With The Prevalence Of Iron Deficiency And Anemia In Women Of Reproductive Age In The U.S.: Nhanes 2015-2020, Catherine Wise

All Master's Theses

Iron deficiency (ID) is well recognized as the most prevalent nutrient insufficiency and a leading cause of anemia. Women of reproductive age (WRA), females 15 to 49, are at an increased risk of ID and anemia. This is due to the heightened iron demands of this life stage, including puberty, menstruation, and pregnancy, which require iron intakes ranging from 15 to 27 mg/day. Poor health and nutrition increase the risk of ID and progression to anemia. Consequences of ID and anemia range from exhaustion and decreased cognitive function to an increased risk of mortality. This study aimed to assess the …

Dietitian & Physician Preferences Of Fiber Use In Enteral Nutrition: A Pilot Study, Holly Gauthun, Thy Pham, Cory Gheen, Liang Ji, Edward Bitok, Susie Ray

Loma Linda University Research Reports

This pilot study examines the beliefs and preferences regarding fiber use in enteral nutrition (EN) among physicians and registered dietitians (RDs) for hemodynamically stable critically ill patients. A total of 30 RDs and 12 physicians participated. The majority of both physicians (80%) and RDs (83%) supported fiber use in EN for these patients. All participants with over ten years of experience and all Certified Nutrition Support Clinicians (CNSCs) endorsed fiber use. Despite expectations, no significant difference in support was found between RDs and physicians. The study reveals a noteworthy shift towards endorsing fiber use in enteral nutrition for hemodynamically stable …

Association Between Early Childhood Feeding Practices And Parental Perception Of Picky Eating, Yue-Liang Brewerton, Anoud Mohammad, Linda Navarro, Cindy Kosch, Gurinder Bains, Liang Ji, Edward Bitok

Loma Linda University Research Reports

Introduction: This study aimed to investigate the association between early childhood feeding practices and picky eating behaviors in children aged 5-10 years.

Methods: Forty-three parents or legal guardians of children aged 5-10 completed the Child Feeding Questionnaires (CFQ) and the Children’s Eating Behavior Questionnaire (CEBQ) to assess parental control in child feeding and child eating behaviors, respectively. Logistic regression was used to analyze the relationship between the exposure and outcome variables.

Results: Infants fed store-bought food didn't differ significantly in picky eating from those fed self-made food, challenging conventional assumptions. Additionally, while socioeconomic status and parental education didn't show significant …

Effects Of Intuitive Eating Principles And Magnesium Glycinate On Quality Of Life, Body Satisfaction, And Stress In Early- And Middle-Aged Adults, Numydia Cotry, Taylor Kalinowski, Angel Wilensky

Loma Linda University Research Reports

This study investigated the impact of combining Intuitive Eating (IE) principles with magnesium glycinate supplementation on adults aged 18 to 49. Participants were split into two groups: one practicing IE alone and another receiving magnesium supplementation alongside IE. Results showed significant improvements in body satisfaction, stress levels, and overall health among those receiving magnesium. Qualitative data indicated enhanced body awareness and well-being with IE. This suggests a promising synergy between IE and magnesium supplementation for better health and quality of life. However, further research with larger samples and longer durations is warranted.

The Effects Of Hydration Status On Grip Strength, Loradelle Feri, Jordan Sales, Angela Li, Devon Cannata, Cindy L. Kosch, Gurinder Bains, Liang Ji, Everett B. Lohman, Lee Berk, Edward K. Bitok

Loma Linda University Research Reports

Introduction: This study aimed to investigate the influence of hydration status on hand grip strength in a sample of the general population.

Methods: Fourteen participants (4 males and 10 females) aged 18 and older, were recruited from the Loma Linda University area. Participants underwent multiple clinic visits, where they were randomly assigned to either optimal or suboptimal hydration conditions. Measurements included hand grip strength using a dynamometer, extracellular water ratio via bioimpedance analysis, and urine specific gravity.

Results: There was no significant differences in hand grip strength, extracellular water ratio, or urine specific gravity between optimal and suboptimal hydration states. …

Assessment Of Quality Of Life Among Patients Undergoing Semaglutide Treatment For Weight Loss, Muhammad Sameed

Honors Undergraduate Theses

Purpose: The study aims to assess the Quality of Life (QoL) among patients undergoing semaglutide treatment for weight loss. The primary hypothesis is that patients’ QoL will improve after semaglutide treatment. This can be due to losing weight, having better physical and mental health, or due to the perceived betterment in life after treatment.

Introduction: Obesity is becoming more prevalent in America, and it has a huge effect on the person's medical conditions, life expectancy, and QoL. Though there has been a surge of treatments to deter the obesity rates in America from rising. One of the more popular and …

Understanding Guardian Perceptions Of Whole-Foods Plant-Based Diets As Interventions In Pediatric Medicine, Vijay R. Luthra

Honors Undergraduate Theses

The obesity epidemic is widespread in American society, often affecting children who bear its consequences innocently. Due to a lack of nutrition knowledge, children rely on caregivers to meet their nutritional needs and instill healthy habits. This study examines parents' attitudes, knowledge, and behaviors, as well as perceived barriers to adopting a whole-foods plant-based diet (WFPD) for their children. Using a modified survey instrument by Morton et al., this study focused on parents and children regarding dietary choices. Participants were recruited from the waiting area of a pediatric clinic at the Medical College of Georgia between April and May 2023. …

The Impact Of Gestational Diabetes Mellitus And Maternal Oral Microbiome: A Scoping Review, Jaclyn P. Langan

Honors Undergraduate Theses

Background: Gestational diabetes mellitus (GDM) is a common pregnancy-related metabolic disorder associated with adverse maternal and fetal outcomes. Recent research has highlighted the potential role of the oral microbiome in the pathophysiology of various systemic conditions, including diabetes mellitus. However, the impact of GDM on the maternal oral microbiome remains relatively understudied. Understanding alterations in the oral microbiome during pregnancy complicated by GDM could provide valuable insights into the mechanistic links between systemic metabolic disorders and oral health.

Objective: The objective of this scoping review was to comprehensively examine the existing literature on the relationship between GDM and maternal oral …

Breakfast Skipping In College Students And Its Association With Eating Behaviors, Rebekah E. May

Honors Undergraduate Theses

Background: Breakfast is important in maintaining optimal diet quality and decreasing preventable diet-related disease later in life. Breakfast skipping is highly prevalent in the college population, potentially decreasing self-regulation and diet quality and increasing habits of overeating. However, specific eating styles and diet quality have yet to be studied in breakfast skippers.

Objective: To explore and compare the characteristics of eating style, self-regulation, and diet quality among college students between a day when breakfast is skipped and a day when breakfast is consumed.

Methodology: Undergraduate students (n=103) participating in this observational crossover study completed demographics, the Self-regulation of Eating Behavior …

Examining The Relationship Between Physical Health Behaviors And Mental Health Outcomes In Female Hispanic College Students, Alexandra St. Laurent

Honors Undergraduate Theses

The current state of mental health in college students is a universal concern. Female college students are reporting more depression, anxiety, and stress symptoms than ever before. Physical activity and diet quality can positively influence mental health symptoms. Current research provides scarce evidence that examines the relationship of these health behaviors and outcomes in the Hispanic female population. The primary aim of this study is to examine the relationship between physical health behaviors and mental health outcomes in Hispanic female college students. This is a cross-sectional study using a self-report survey to collect data from approximately 109 Hispanic female college …

Pediatric Dentists’ Considerations Concerning Obesity-Related Education For Parents Of Young Children: Who Should Educate About What, How And When?, Arianne Swanson Dds, Ms, James R. Boynton Dds, Ms, Larry B. Salzmann Dds, Yu-Ju Yang Dds, Marita R. Inglehart Dipl. Psych., Dr. Phil., Dr. Phil. Habil

The Journal of the Michigan Dental Association

This study aimed to explore pediatric dentists' perspectives on obesity-related interventions for parents of young children. A web-based survey was administered to 210 American Academy of Pediatric Dentistry members. Findings revealed that respondents considered it important for various healthcare professionals, especially pediatricians and nurse practitioners, to engage in obesity-related parent education. Strong consensus existed on educating parents about the link between early childhood caries and diet, soft drink and fruit juice consumption, and healthy snacking. The study also found positive attitudes correlated with increased engagement in objective weight determination, data collection, and diet/nutrition counseling.

Silver Diamine Fluoride As A Caries Management Option For The Young Child, Giovana Anovazzi Medeiros Dds, Msc, Phd, Chia-En Tsai Dds, Ms, Nita Singh Dds, James R. Boynton Dds, Ms

The Journal of the Michigan Dental Association

Dental caries is among the most-common childhood diseases around the world, and neglected caries can result in pain, infection, and can have a negative cascading impact on a child’s overall well-being. Definitive care of these lesions involves restorative procedures and/or extractions, but these treatment options require some level of child cooperation, which can sometimes be a challenge with very young children.

Silver diamine fluoride (SDF) is a non-invasive treatment intended to arrest the caries process. SDF is a liquid solution that contains a high concentration of silver and fluoride ions and has been used as an alternative agent for treating …

Catalyzing Communities Of Research Rigour Champions, Audrey C Brumback, William X Q Ngiam, Dana M Lapato, David B Allison, Christin L Daniels, Michael Dougherty, Haley F Hazlett, Kara L Kerr, Susan Pusek, Naomi Schrag

Children’s Nutrition Research Center Staff Publications

The biomedical sciences must maintain and enhance a research culture that prioritizes rigour and transparency. The US National Institute of Neurological Disorders and Stroke convened a workshop entitled 'Catalyzing Communities of Research Rigor Champions' that brought together a diverse group of leaders in promoting research rigour and transparency (identified as 'rigour champions') to discuss strategies, barriers and resources for catalyzing technical, cultural and educational changes in the biomedical sciences. This article summarizes 2 days of panels and discussions and provides an overview of critical barriers to research rigour, perspectives behind reform initiatives and considerations for stakeholders across science. Additionally, we …

A Comprehensive Review Of Advances In Hepatocyte Microencapsulation: Selecting Materials And Preserving Cell Viability, Hailian Wang, Lebin Wen, Fengdi Jiang, Pengyu Ren, Yixin Yang, Siyuan Song, Zhengteng Yang, Yi Wang

Children’s Nutrition Research Center Staff Publications

Liver failure represents a critical medical condition with a traditionally grim prognosis, where treatment options have been notably limited. Historically, liver transplantation has stood as the sole definitive cure, yet the stark disparity between the limited availability of liver donations and the high demand for such organs has significantly hampered its feasibility. This discrepancy has necessitated the exploration of hepatocyte transplantation as a temporary, supportive intervention. In light of this, our review delves into the burgeoning field of hepatocyte transplantation, with a focus on the latest advancements in maintaining hepatocyte function, co-microencapsulation techniques, xenogeneic hepatocyte transplantation, and the selection of …

Sustainability Via Active Garden Education (Sage): The Process Of Incorporating Watering Into Structured Preschool Curriculum, Rebecca E Lee, Anel Arriola, Elizabeth Lorenzo, Erica G Soltero, Jacob Szeszuski

Children’s Nutrition Research Center Staff Publications

School gardens provide rich outdoor learning opportunities for young children. Practical considerations about garden maintenance, in particular, watering, can impeed success. This manuscript chronicles the development of garden maintenance strategies in Sustainability via Active Garden Education (SAGE). SAGE installed raised-bed gardens and provided a complete curriculum focused on increasing children's active time and improving healthy eating habits while fostering garden stewardship. SAGE was implemented by trained research personnel in four early care and education (ECE) facilities in Houston, Texas (SAGE 1, Summer, 2013), one ECE facility in Phoenix, Arizona (SAGE 2, Spring, 2017), and 24 ECE facilities in Phoenix, Arizona …

Adjusting For Covariates Representing Potential Confounders, Mediators, Or Competing Predictors In The Presence Of Measurement Error: Dispelling A Potential Misapprehension And Insights For Optimal Study Design With Nutritional Epidemiology Examples, Roger S Zoh, Diana M Thomas, Carmen D Tekwe, Xiaoxin Yu, Colby J Vorland, Nikhil V Dhurandhar, David M Klurfeld, David B Allison

Children’s Nutrition Research Center Staff Publications

Background: Variables such as dietary intake are measured with error yet frequently used in observational epidemiology. Although this limitation is sometimes noted, these variables are still often modeled as covariates without formal correction or sincere dialogue about measurement unreliability potentially weakening the validity of statistical conclusions. Further, larger sample sizes increase power (bias) to detect spurious correlations. Counterintuitively, recent work suggested a non-monotonic relationship between confounder unreliability and how much controlling for the confounder reduces (or induces) bias when testing for an exposure-outcome association. If true, such non-monotonicity would be especially concerning for applications such as nutrition, where measurement reliability …

Objective Assessment Of Shared Plate Eating Using A Wearable Camera In Urban And Rural Households In Ghana, Christabel A Domfe, Megan A Mccrory, Edward Sazonov, Tonmoy Ghosh, Viprav Raju, Gary Frost, Matilda Steiner-Asiedu, Mingui Sun, Wenyan Jia, Tom Baranowski, Benny Lo, Alex K Anderson

Children’s Nutrition Research Center Staff Publications

Background: Shared plate eating (SPE), defined as two or more individuals eating directly from the same plate or bowl, is a common household food consumption practice in many Low- and Middle-Income Countries (LMICs). Examination of household engagement in SPE remains largely unexplored, highlighting a gap in research when interpreting dietary information obtained from these settings. The dearth of research into SPE can be attributed to the inherent limitations of traditional dietary assessment methods which constrain their usability in settings where SPE is common.

Objective: In this expository narrative, we describe what SPE is when it is practiced in an LMIC …

Combinatorial Atoh1, Gfi1, Pou4f3, And Six1 Gene Transfer Induces Hair Cell Regeneration In The Flat Epithelium Of Mature Guinea Pigs, Yujie Liu, Lin Yang, Sunita Singh, Lisa A Beyer, Diane M Prieskorn, Donald L Swiderski, Andrew K Groves, Yehoash Raphael

Children’s Nutrition Research Center Staff Publications

Flat epithelium (FE) is a condition characterized by the loss of both hair cells (HCs) and supporting cells and the transformation of the organ of Corti into a simple flat or cuboidal epithelium, which can occur after severe cochlear insults. The transcription factors Gfi1, Atoh1, Pou4f3, and Six1 (GAPS) play key roles in HC differentiation and survival in normal ears. Previous work using a single transcription factor, Atoh1, to induce HC regeneration in mature ears in vivo usually produced very few cells and failed to produce HCs in severely damaged organs of Corti, especially those with FE. Studies in vitro …