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Disparate Degrees Of Hypervariable Loop Flexibility Control T Cell Receptor Cross-Reactivity, Specificity, And Binding Mechanism, Daniel R. Scott, Oleg Y. Borbulevych, Kurt H. Piepenbrink, Steven A. Corcelli, Brian M. Baker 2011 University of Notre Dame

Disparate Degrees Of Hypervariable Loop Flexibility Control T Cell Receptor Cross-Reactivity, Specificity, And Binding Mechanism, Daniel R. Scott, Oleg Y. Borbulevych, Kurt H. Piepenbrink, Steven A. Corcelli, Brian M. Baker

Food for Health: Publications

αβ T cell receptors recognize multiple antigenic peptides bound and presented by major histocompatibility complex molecules. TCR cross-reactivity has been attributed in part to flexibility of the complementarity-determining region loops, yet there have been limited direct studies of loop dynamics to determine the extent of its role. Here we studied the flexibility of the binding loops of the αβ TCR A6 utilizing crystallographic, spectroscopic, and computational methods. A significant role for flexibility in binding and cross-reactivity was indicated only for the CDR3α and CDR3β hypervariable loops. Examination of the energy landscapes of these two loops indicated that CDR3β possesses a …


How Does The Rural Food Environment Affect Rural Childhood Obesity?, David Hartley PhD, MHA, Nathaniel J. Anderson MS, MPH, Kimberley Fox MPH, Jennifer D. Lenardson MHS 2011 University of Southern Maine, Muskie School of Public Service, Maine Rural Health Research Center

How Does The Rural Food Environment Affect Rural Childhood Obesity?, David Hartley Phd, Mha, Nathaniel J. Anderson Ms, Mph, Kimberley Fox Mph, Jennifer D. Lenardson Mhs

Population Health

Objective: Assess the impact of the rural food environment on the eating behaviors and BMI of rural low-income children. Method: Statewide (Maine, 2009) household survey of parents of children on Medicaid (n=1722), oversampled in six rural communities, resulting in n=272 for six target communities. Food environment measured using modified Nutrition Environment Measures Survey in Stores (NEMS-S) for 46 retail food outlets. Multi-variate analysis assessed factors affecting home food environment, child's eating behavior and BMI. Results: Home food behaviors (how often: family eats together, child eats breakfast, vegetables served) and parent food consumption were significantly associated with children's healthy eating behaviors. …


Constructive Developmental Theory: An Alternative Approach To Leadership, Anne Marie B. Hunter, Nancy M. Lewis, Paula K. Ritter-Gooder 2011 Missouri State University - Springfield

Constructive Developmental Theory: An Alternative Approach To Leadership, Anne Marie B. Hunter, Nancy M. Lewis, Paula K. Ritter-Gooder

Department of Nutrition and Health Sciences: Faculty Publications

As early as 1954, the critical value of leadership in dietetics was described by Rourke, who wrote, “When the day comes that your executive abilities equal your scientific knowledge, your profession (dietetics) will be secure. Until that day, you will be faced with a constant and unwelcome challenge” (1). Career and leadership skills development have been identified as an area for further attention by American Dietetic Association (ADA) practitioners and student members (2). Creation of the ADA Leadership Institute in 2003 represented an awareness of the need to invest in developing dietetic leaders (3). Proficient leaders are critical in keeping …


The Effects Of 24r, 25-Dihydroxyvitamin D3 And 24s, 25-Dihydroxyvitamin D3 On Phosphate Transport In Vivo, Yu Meng 2011 Utah State University

The Effects Of 24r, 25-Dihydroxyvitamin D3 And 24s, 25-Dihydroxyvitamin D3 On Phosphate Transport In Vivo, Yu Meng

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This research studied the effects of the two isomers of 24,25(OH)2D3 on phosphate absorption in vivo to increase our understanding of the effects of 24,25(OH)2D3 on phosphate transport in vivo, and its two isomers. The current work demonstrates that 24R,25(OH)2D3 is capable of decreasing phosphate absorption after a 1h injection in vivo and 24S,25(OH)2D3 can increase phosphate absorption after a 5h injection, but this stimulation disappears at time points after 5h.

Since 24,25(OH)2D3 is made in vitamin D-replete animals, the observation that 24R,25(OH)2D …


The Effect Of Six Weeks Of Oral Echinacea Supplementation On Erythropoiesis, Nitric Oxide Production, And Exercise Performance, Tyler David Martin 2011 University of Southern Mississippi

The Effect Of Six Weeks Of Oral Echinacea Supplementation On Erythropoiesis, Nitric Oxide Production, And Exercise Performance, Tyler David Martin

Dissertations

The purpose of the present study was to investigate the effect of six weeks of oral Echinacea supplementation on serum erythropoietin (EPO) and erythropoietic status, plasma nitric oxide [NO], submaximal endurance exercise performance, and maximal oxygen uptake (V˙O2max). Twenty-four males (mean ± SE): age = 25.2 ± 1.4 yr, height = 178.1 ± 1.4 cm, mass = 78.1 ± 1.6 kg, percent body fat = 12.7 ± 0.9 %, V˙Omax = 52.9 ± 0.9 mL·kg-1·min-1 were randomly grouped using a matched-pair, double-blind design and self-administered 8,000 mg·d-1(5 × 400 mg × 4 …


Development Of An Instrument Measuring The Perceived Attributes Of Using A Healthy Diet Innovation, Holly Ann Federico Huye 2011 University of Southern Mississippi

Development Of An Instrument Measuring The Perceived Attributes Of Using A Healthy Diet Innovation, Holly Ann Federico Huye

Dissertations

The Lower Mississippi Delta (LMD) is a rural region that is rich in agricultural resources but is one of the most impoverished areas in the US. Prior research has indicated LMD adults as having higher rates of obesity and diet-related chronic diseases as compared to US adults. While the need for dietary intervention in the LMD is evident, the first step in designing effective interventions is the assessment of one’s perceptions of dietary behaviors. The purpose of this research was to develop a valid and reliable instrument to assess individuals’ perceived attributes of using a healthy diet. Using the Diffusion …


Supplemental Fish Oil Decreases Urinary Excretion Of A Marker Of Bone Resorption In Healthy Adults, Eric E. Noreen, Josef Brandauer, Megan H. MacNabb 2011 Gettysburg College

Supplemental Fish Oil Decreases Urinary Excretion Of A Marker Of Bone Resorption In Healthy Adults, Eric E. Noreen, Josef Brandauer, Megan H. Macnabb

Health Sciences Faculty Publications

Background: Incorporation of fish oil (FO) into the diet of rodents has been shown to result in positive changes in bone health. Currently it is poorly understood if FO has the same effects on bone health in humans. The purpose of this study was to determine the effects of supplemental FO on levels of urinary N-terminal cross-linked telopeptide (NTx), which is a marker of bone breakdown, and how this is related to the morning levels of salivary cortisol and urinary excretion of interleukin 6 (IL-6).

Methods: A total of twenty-eight females and twelve males(35 ± 13yrs; 69.1 ± 14.1kg; 29.4 …


Characterization Of Street Food Consumption In Palermo: Possible Effects On Health, Silvio Buscemi, Annamaria Barile, Vincenza Maniaci, John A. Batsis 2011 University of Palermo

Characterization Of Street Food Consumption In Palermo: Possible Effects On Health, Silvio Buscemi, Annamaria Barile, Vincenza Maniaci, John A. Batsis

Dartmouth Scholarship

Background: Street Food (SF) consists of out-of-home food consumption and has old, historical roots with complex social-economic and cultural implications. Despite the emergence of modern fast food, traditional SF persists worldwide, but the relationship of SF consumption with overall health, well-being, and obesity is unknown.

Methods: This is an observational, cross-sectional study. The study was performed in Palermo, the largest town of Sicily, Italy. Two groups were identified: consumers of SF (n = 687) and conventional restaurant food (RES) consumers (n = 315). Study subjects answered a questionnaire concerning their health conditions, nutritional preferences, frequency of consumption of SF and …


Beverage Consumption And Bmi Of British Schoolchildren Aged 9-13 Years, Tara Coppinger, Y. M. Jeanes, M. Mitchell, S. Reeves 2011 Department of Sport, Leisure & Childhood Studies, Cork Institute of Technology, Cork, Ireland

Beverage Consumption And Bmi Of British Schoolchildren Aged 9-13 Years, Tara Coppinger, Y. M. Jeanes, M. Mitchell, S. Reeves

Publications

Objective Adequate fluid intake has been well documented as important for health but whether it has adverse effects on overall energy and sugar intakes remains under debate. Many dietary studies continue to refrain from reporting on beverage consumption, which the present study aimed to address. Design A cross-sectional survey investigated self-reported measures of dietary intake and anthropometric measurements. Setting Primary and secondary schools in south-west London, UK. Subjects Boys and girls (n 248) aged 9-13 years. Results Boys consumed 10 % and girls consumed 9 % of their daily energy intake from beverages and most children had total sugar intakes …


We Are… Bridging Medicine And Science Vol. 1, Issue 1, Fall 2011, Marshall University Biomedical Sciences 2011 Marshall University

We Are… Bridging Medicine And Science Vol. 1, Issue 1, Fall 2011, Marshall University Biomedical Sciences

We Are... Bridging Medicine Science

No abstract provided.


Perceived Importance And Actual Intake Of Calcium And Vitamin D In Young Female Athletes, Miriam E. Zambrano 2011 University of Nebraska-Lincoln

Perceived Importance And Actual Intake Of Calcium And Vitamin D In Young Female Athletes, Miriam E. Zambrano

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Calcium needs increase as a child grows. Actual intake often decreases as a child gets older, leaving his/her developing bones at risk for injury during childhood and increasing the risk of developing osteoporosis later in life. The purpose of this study was to investigate relationships between psychosocial factors influencing consumption of calcium and vitamin D-rich foods and actual intakes of these nutrients. We examined the dietary calcium and vitamin D intakes, determined serum vitamin D levels, and assessed nutrition knowledge and perception of a sample of 20 young girls participating in competitive cheerleading in Omaha, Nebraska. From this information we …


Supporting School Wellness Policices Through Game On! Implementation In 13 High-Need Connecticut Schools, Sarah M. Bourque 2011 University of Connecticut - Storrs

Supporting School Wellness Policices Through Game On! Implementation In 13 High-Need Connecticut Schools, Sarah M. Bourque

Master's Theses

No abstract provided.


Consumption Of Dha + Epa By Low-Income Women During Pregnancy And Lactation, Carmen L. Nochera, Linda H. Goossen, Annette R. Brutus, Miranda Cristales, Bethany Eastman 2011 Grand Valley State University

Consumption Of Dha + Epa By Low-Income Women During Pregnancy And Lactation, Carmen L. Nochera, Linda H. Goossen, Annette R. Brutus, Miranda Cristales, Bethany Eastman

Peer Reviewed Articles

No abstract provided.


A Formative Evaluation For A Food Choices Intervention In A Mississippi Delta Community: A Focus Group Of Rural African American Adolescents, Jovan Chantrell Eugene Williams 2011 University of Southern Mississippi

A Formative Evaluation For A Food Choices Intervention In A Mississippi Delta Community: A Focus Group Of Rural African American Adolescents, Jovan Chantrell Eugene Williams

Master's Theses

A needs assessment should be conducted to plan effective interventions. This study used a qualitative research approach to examine the eating patterns, food purchasing and preparation skills and practices, barriers and facilitators of dietary change, social and contextual influences on food choices, and preferences for communication and presentation channels and styles of low-income rural African American adolescents. Seven focus groups were conducted with a total of 33 participants, 21 girls and 12 boys, aged 13-18. Adolescents were grouped by age and gender. A moderator, who was trained in focus group methodology, conducted the session using a focus group discussion guide …


Latent Growth Modeling Of A Nutrition And Physical Activity Intervention, Alicia Dea Sample 2011 University of Southern Mississippi

Latent Growth Modeling Of A Nutrition And Physical Activity Intervention, Alicia Dea Sample

Dissertations

The health, economic, and social impacts of physical inactivity and unhealthy dietary patterns are quite significant and evidenced by the fact that only 3-4% of American adults follow all the dietary advice recommended by the Dietary Guidelines for Americans (DGA; Kohatsu, Robinson, & Torner, 2004), and specific subpopulations, including the rural South, are affected even more drastically (McCabe-Sellers et al., 2007). Furthermore, the majority of the people in the United States do not currently meet recommended amounts of physical activity (PA) and have not since the mid 1980s (U.S. Department of Health and Human Services [USDHHS], 2008). To address the …


Factors Associated With Duration Of Breastfeeding In Ireland: Potential Areas For Improvement, Roslyn Tarrant, Katherine Younger, Margaret Sheridan Pereira, John Kearney 2011 Technological University Dublin

Factors Associated With Duration Of Breastfeeding In Ireland: Potential Areas For Improvement, Roslyn Tarrant, Katherine Younger, Margaret Sheridan Pereira, John Kearney

Articles

There is a need to comprehensively examine why mothers in Ireland discontinue breastfeeding early and to explore thefactors influencing duration of breastfeeding during the first 6 months postpartum. Findings from this study provide valuabledirection for future strategies and interventions aimed at increasing breastfeeding duration rates in Ireland.


Effects Of Single Nucleotide Polymorphisms In The Human Holocarboxylase Synthetase Gene On Catalytic Activity, Shingo Esaki 2011 University of Nebraska-Lincoln

Effects Of Single Nucleotide Polymorphisms In The Human Holocarboxylase Synthetase Gene On Catalytic Activity, Shingo Esaki

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Holocarboxylase synthetase (HCS) catalyzes the covalent binding of biotin to carboxylases and histones in eukaryotic cells. Biotinylated carboxylases play essential roles in the metabolism of fatty acids, amino acids, and glucose; biotinylated histones play essential roles in gene regulation and genome stability. HCS null individuals are not viable whereas HCS deficiency is linked to developmental delays and phenotypes such as short life span and low stress resistance. Greater than 2,500 single nucleotide polymorphisms (SNPs) have been reported for HCS, but the biological importance of these polymorphisms is unknown. We hypothesized that some of these SNPs impair catalytic activity and that …


Intervention To Increase Knowledge And Consumption Of Folate-Rich Foods Based On The Health Belief Model, Lindsay M. LaBrosse 2011 University of Nebraska-Lincoln

Intervention To Increase Knowledge And Consumption Of Folate-Rich Foods Based On The Health Belief Model, Lindsay M. Labrosse

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Folate is important in the prevention of birth defects and in the maintenance of general health. Even after mandatory fortification, many people are still not consuming the RDA of 400 mcg/day. Consuming a diet rich in naturally high-folate foods, as opposed to supplementation, may offer additional health benefits and promote an overall healthy diet.

The purpose of this pilot study was to test the hypothesis that a learner-centered educational intervention based on the Health Belief Model (HBM) will successfully increase knowledge and consumption of folate-rich foods, while increasing positive beliefs about folate and health. A two group parallel control trial …


Farm To School: A Case Study Of Four Rural Nebraska Schools Before Initiating Locally Grown Foods In School Food Service, Morgan Swisher 2011 University of Nebraska-Lincoln

Farm To School: A Case Study Of Four Rural Nebraska Schools Before Initiating Locally Grown Foods In School Food Service, Morgan Swisher

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

More than 25% of children in the U.S. are overweight. Farm to School is a program that encourages schools to procure local produce and nutrition education in an effort to improve childhood nutrition. A case study involving four schools has examined the attitudes of food service managers, food service staff members, and educators who are about to incorporate this program into their schools. Food service managers were interviewed about the foods they intend to purchase, food safety, menu planning, expected costs and receiving, additional training, and staff interest. From the qualitative study, the following themes were found: “More work for …


Effects Of Diet Type And Supplementation Of Glucosamine, Chondroitin, And Msm On Body Composition, Functional Status, And Markers Of Health In Women With Knee Osteoarthritis Initiating A Resistance-Based Exercise And Weight Loss Program, Teresa Magrans-Courtney, Colin Wilborn, Christopher Rasmussen, Maria Pontes Ferreira, Lori Greenwood, Bill Campbell, Chad M. Kerksick, Erica Nassar, Rui Li, Mike Iosia, Matt Cooke, Kristin Dugan, Darryn Willoughby, LuAnn Soliah, Richard B. Kreider 2011 Baylor University

Effects Of Diet Type And Supplementation Of Glucosamine, Chondroitin, And Msm On Body Composition, Functional Status, And Markers Of Health In Women With Knee Osteoarthritis Initiating A Resistance-Based Exercise And Weight Loss Program, Teresa Magrans-Courtney, Colin Wilborn, Christopher Rasmussen, Maria Pontes Ferreira, Lori Greenwood, Bill Campbell, Chad M. Kerksick, Erica Nassar, Rui Li, Mike Iosia, Matt Cooke, Kristin Dugan, Darryn Willoughby, Luann Soliah, Richard B. Kreider

Nutrition and Food Science Faculty Research Publications

Background: The purpose of this study was to determine whether sedentary obese women with knee OA initiating an exercise and weight loss program may experience more beneficial changes in body composition, functional capacity, and/or markers of health following a higher protein diet compared to a higher carbohydrate diet with or without GCM supplementation.

Methods: Thirty sedentary women (54 ± 9 yrs, 163 ± 6 cm, 88.6 ± 13 kg, 46.1 ± 3% fat, 33.3 ± 5 kg/m2) with clinically diagnosed knee OA participated in a 14-week exercise and weight loss program. Participants followed an isoenergenic low fat higher …


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