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Articles 61 - 90 of 1525
Full-Text Articles in Medicine and Health Sciences
Multi-Marker Immunofluorescent Staining And Pd-L1 Detection On Circulating Tumour Cells From Ovarian Cancer Patients, Du-Bois Asante, Michael Morici, Ganendra R. K. A. Mohan, Emmanuel Acheampong, Isaac Spencer, Weitao Lin, Paula Van Miert, Samantha Gibson, Aaron B. Beasley, Melanie Ziman, Leslie Calapre, Tarek M. Meniawy, Elin S. Gray
Multi-Marker Immunofluorescent Staining And Pd-L1 Detection On Circulating Tumour Cells From Ovarian Cancer Patients, Du-Bois Asante, Michael Morici, Ganendra R. K. A. Mohan, Emmanuel Acheampong, Isaac Spencer, Weitao Lin, Paula Van Miert, Samantha Gibson, Aaron B. Beasley, Melanie Ziman, Leslie Calapre, Tarek M. Meniawy, Elin S. Gray
Research outputs 2014 to 2021
Detection of ovarian cancer (OC) circulating tumour cells (CTCs) is primarily based on targeting epithelial markers, thus failing to detect mesenchymal tumour cells. More importantly, the immune checkpoint inhibitor marker PD-L1 has not been demonstrated on CTCs from OC patients. An antibody staining protocol was developed and tested using SKOV-3 and OVCA432 OC cell lines. We targeted epithelial (cytokeratin (CK) and EpCAM), mesenchymal (vimentin), and OC-specific (PAX8) markers for detection of CTCs, and CD45/16 and CD31 were used for the exclusion of white blood and vascular endothelial cells, respectively. PD-L1 was used for CTC characterisation. CTCs were enriched using the …
“Coronavirus Changed The Rules On Everything”: Parent Perspectives On How The Covid‐19 Pandemic Influenced Family Routines, Relationships And Technology Use In Families With Infants, Rebecca Hood, Juliana Zabatiero, Desiree Silva, Stephen R. Zubrick, Leon Straker
“Coronavirus Changed The Rules On Everything”: Parent Perspectives On How The Covid‐19 Pandemic Influenced Family Routines, Relationships And Technology Use In Families With Infants, Rebecca Hood, Juliana Zabatiero, Desiree Silva, Stephen R. Zubrick, Leon Straker
Research outputs 2014 to 2021
This study explores how the first wave of the COVID‐19 pandemic influenced family routines, relationships and technology use (smartphones and tablet computers) among families with infants. Infancy is known to be an important period for attachment security and future child development, and a time of being susceptible to changes within and outside of the family unit. A qualitative design using convenience sampling was employed. A total of 30 mothers in Perth, Western Australia participated in semi‐structured interviews by audio or video call. All mothers were parents of infants aged 9 to 15 months old. Interviews were audio‐recorded and transcribed, and …
Influence Of Physical And Technical Aspects On Change Of Direction Performance Of Rugby Players: An Exploratory Study, Tomás T. Freitas, Pedro E. Alcaraz, Julio Calleja-González, Ademir F. S. Arruda, Aristide Guerriero, Valter P. Mercer, Lucas A. Pereira, Felipe P. Carpes, Michael R. Mcguigan, Irineu Loturco
Influence Of Physical And Technical Aspects On Change Of Direction Performance Of Rugby Players: An Exploratory Study, Tomás T. Freitas, Pedro E. Alcaraz, Julio Calleja-González, Ademir F. S. Arruda, Aristide Guerriero, Valter P. Mercer, Lucas A. Pereira, Felipe P. Carpes, Michael R. Mcguigan, Irineu Loturco
Research outputs 2014 to 2021
We examined the relationships between change of direction (COD) speed and deficit, and a series of speed-and power-related measurements in national team rugby union players and analyzed the influence of movement patterns on COD ability. Eleven male athletes completed the following physical assessments on different days: day 1—anthropometric measurements, and lower-body kinematic parameters (assessed with eight inertial sensors) and completion time in COD tests (proagility, 45◦ cutting maneuver (CUT), and “L” (L-Drill)); day 2—bilateral and unilateral squat and countermovement jumps, 40 m linear sprint, and bar-power output in the jump squat and half-squat exercises. Pearson’s product–moment correlations were performed to …
The Enablers And Barriers To Children Visiting Their Ill Parent/Carer In Intensive Care Units: A Scoping Review, Beverley Ewens, Doreen Collyer, Vivien Kemp, Diana Arabiat
The Enablers And Barriers To Children Visiting Their Ill Parent/Carer In Intensive Care Units: A Scoping Review, Beverley Ewens, Doreen Collyer, Vivien Kemp, Diana Arabiat
Research outputs 2014 to 2021
Aim: The aim of the study was to identify the enablers and/or barriers to children visiting their ill parent/carer in intensive care units by examining the visiting policies as practiced or perceived by nurses and experienced or perceived by parents and caregivers. Review method: This is a scoping review following Joanna Briggs Institute Protocol Guidelines. Data sources: An extensive literature search of Cumulative Index of Nursing and Allied Health Literature, Medical Literature Analysis and Retrieval System Online, PsychINFO, PubMed, and Excerpta Medica dataBASE databases, using key terms, was conducted between May 2019 and July 2020; studies published between 1990 and …
Insights Into The Complexity Of Presentation And Management Of Patients: The Sport And Exercise Physician’S Perspective, Prasanna J. Gamage, Saran Seker, Jessica Orchard, David Humphries, Kylie Fitzgerald, Jane Fitzpatrick
Insights Into The Complexity Of Presentation And Management Of Patients: The Sport And Exercise Physician’S Perspective, Prasanna J. Gamage, Saran Seker, Jessica Orchard, David Humphries, Kylie Fitzgerald, Jane Fitzpatrick
Research outputs 2014 to 2021
Objectives:
Sport and Exercise Physicians represent a relatively new specialty focusing on exercise in complex diseases including musculoskeletal diseases. Our objective was to describe the characteristics, type and complexity of patient presentations, their management strategies and referral information in Australian practice.
Methods:
A cross-sectional study including a cohort of 11 senior Sport and Exercise Physicians in Australia studied all new patient consultations within an 8-week period. Data were analysed relating to presentation, referral source, follow-up referrals, and patient management strategies.
Results:
Data from 419 patients were recorded. The majority, 97% (n=406), had musculoskeletal conditions, 53% (n=222) had one or more …
Clinical Trial Of Abcb5+ Mesenchymal Stem Cells For Recessive Dystrophic Epidermolysis Bullosa, Dimitra Kiritsi, Kathrin Dieter, Elke Niebergall-Roth, Silvia Fluhr, Cristina Daniele, Jasmina Esterlechner, Samar Sadeghi, Seda Ballikaya, Leoni Erdinger, Franziska Schauer, Stella Gewert, Martin Laimer, Johann W. Bauer, Alain Hovnanian, Giovanna Zambruno, May El Hachem, Emmanuelle Bourrat, Maria Papanikolaou, Gabriela Petrof, Sophie Kitzmüller, Christen L. Ebens, Markus H. Frank, Natasha Y. Frank, Christoph Ganss, Anna E. Martinez, John A. Mcgrath, Jakub Tolar, Mark A. Kluth
Clinical Trial Of Abcb5+ Mesenchymal Stem Cells For Recessive Dystrophic Epidermolysis Bullosa, Dimitra Kiritsi, Kathrin Dieter, Elke Niebergall-Roth, Silvia Fluhr, Cristina Daniele, Jasmina Esterlechner, Samar Sadeghi, Seda Ballikaya, Leoni Erdinger, Franziska Schauer, Stella Gewert, Martin Laimer, Johann W. Bauer, Alain Hovnanian, Giovanna Zambruno, May El Hachem, Emmanuelle Bourrat, Maria Papanikolaou, Gabriela Petrof, Sophie Kitzmüller, Christen L. Ebens, Markus H. Frank, Natasha Y. Frank, Christoph Ganss, Anna E. Martinez, John A. Mcgrath, Jakub Tolar, Mark A. Kluth
Research outputs 2014 to 2021
BACKGROUND. Recessive dystrophic epidermolysis bullosa (RDEB) is a rare, devastating, and lifethreatening inherited skin fragility disorder that comes about due to a lack of functional type VII collagen, for which no effective therapy exists. ABCB5+ dermal mesenchymal stem cells (ABCB5+ MSCs) possess immunomodulatory, inflammation-dampening, and tissue-healing capacities. In a Col7a1-/-mouse model of RDEB, treatment with ABCB5+ MSCs markedly extended the animals' lifespans. METHODS. In this international, multicentric, single-arm, phase I/IIa clinical trial, 16 patients (aged 4-36 years) enrolled into 4 age cohorts received 3 i.v. infusions of 2 × 106ABCB5+ MSCs/kg on days 0, 17, and 35. Patients were followed …
Higher Coffee Consumption Is Associated With Slower Cognitive Decline And Less Cerebral Aβ-Amyloid Accumulation Over 126 Months: Data From The Australian Imaging, Biomarkers, And Lifestyle Study, Samantha L. Gardener, Stephanie R. Rainey-Smith, Victor L. Villemagne, Jurgen Fripp, Vincent Doré, Pierrick Bourgeat, Kevin Taddei, Christopher Fowler, Colin L. Masters, Paul Maruff, Christopher C. Rowe, David Ames, Ralph N. Martins, Aibl Investigators
Higher Coffee Consumption Is Associated With Slower Cognitive Decline And Less Cerebral Aβ-Amyloid Accumulation Over 126 Months: Data From The Australian Imaging, Biomarkers, And Lifestyle Study, Samantha L. Gardener, Stephanie R. Rainey-Smith, Victor L. Villemagne, Jurgen Fripp, Vincent Doré, Pierrick Bourgeat, Kevin Taddei, Christopher Fowler, Colin L. Masters, Paul Maruff, Christopher C. Rowe, David Ames, Ralph N. Martins, Aibl Investigators
Research outputs 2014 to 2021
Background:
Worldwide, coffee is one of the most popular beverages consumed. Several studies have suggested a protective role of coffee, including reduced risk of Alzheimer’s disease (AD). However, there is limited longitudinal data from cohorts of older adults reporting associations of coffee intake with cognitive decline, in distinct domains, and investigating the neuropathological mechanisms underpinning any such associations.
Methods: The aim of the current study was to investigate the relationship between self-reported habitual coffee intake, and cognitive decline assessed using a comprehensive neuropsychological battery in 227 cognitively normal older adults from the Australian Imaging, Biomarkers, and Lifestyle (AIBL) study, over …
Genetic Studies Of Metabolic Syndrome In Arab Populations: A Systematic Review And Meta-Analysis, Zahrah Al-Homedi, Nariman Afify, Mashal Memon, Habiba Alsafar, Guan Tay, Herbert F. Jelinek, Mira Mousa, Nadia Abu-Samra, Wael Osman
Genetic Studies Of Metabolic Syndrome In Arab Populations: A Systematic Review And Meta-Analysis, Zahrah Al-Homedi, Nariman Afify, Mashal Memon, Habiba Alsafar, Guan Tay, Herbert F. Jelinek, Mira Mousa, Nadia Abu-Samra, Wael Osman
Research outputs 2014 to 2021
Background:
The metabolic syndrome (MetS) is prevalent in Arabian populations. Several small-scale studies have been performed to investigate the genetic basis of MetS. This systematic review and meta-analysis aimed to examine whether candidate gene polymorphisms are associated with MetS susceptibility among ethnic groups of the Arabian world and to suggest possible directions for future research regarding genetic markers and MetS.
Methods:
A search was conducted for peer-reviewed articles that examined the genetic association of MetS in Arabian populations in the following databases: Medline, Embase, Scopus, Direct Science, Web of Science, ProQuest, and Google Scholar until March 31, 2021. Articles were …
Muscle Damage Indicated By Maximal Voluntary Contraction Strength Changes From Immediately To 1 Day After Eccentric Exercise Of The Knee Extensors, Mikio Shoji, Ryoichi Ema, Kazunori Nosaka, Akihiro Kanda, Kosuke Hirata, Ryota Akagi
Muscle Damage Indicated By Maximal Voluntary Contraction Strength Changes From Immediately To 1 Day After Eccentric Exercise Of The Knee Extensors, Mikio Shoji, Ryoichi Ema, Kazunori Nosaka, Akihiro Kanda, Kosuke Hirata, Ryota Akagi
Research outputs 2014 to 2021
The present study examined if the magnitude of changes in indirect muscle damage markers could be predicted by maximal voluntary isometric contraction (MVIC) torque changes from immediately to 1 day after eccentric exercise. Twenty-eight young men performed 100 maximal isokinetic (60°/s) eccentric contractions of the knee extensors. MVIC torque, potentiated doublet torque, voluntary activation (VA) during MVIC, shear modulus of rectus femoris (RF), vastus medialis and lateralis, and muscle soreness of these muscles were measured before, immediately after, and 1–3 days post-exercise. Based on the recovery rate of the MVIC torque from immediately to 1-day post-exercise, the participants were placed …
Higher Habitual Flavonoid Intakes Are Associated With A Lower Incidence Of Diabetes, Nicola P. Bondonno, Frederik Dalgaard, Kevin Murray, Raymond J. Davey, Catherine P. Bondonno, Aedin Cassidy, Joshua R. Lewis, Cecilie Kyrø, Gunnar Gislason, Augustin Scalbert, Anne Tjønneland, Jonathan M. Hodgson
Higher Habitual Flavonoid Intakes Are Associated With A Lower Incidence Of Diabetes, Nicola P. Bondonno, Frederik Dalgaard, Kevin Murray, Raymond J. Davey, Catherine P. Bondonno, Aedin Cassidy, Joshua R. Lewis, Cecilie Kyrø, Gunnar Gislason, Augustin Scalbert, Anne Tjønneland, Jonathan M. Hodgson
Research outputs 2014 to 2021
Background:
Higher flavonoid intakes are hypothesized to confer protection against type 2 diabetes mellitus.
Objectives:
We aimed to 1) investigate associations between flavonoid intakes and diabetes, 2) examine the mediating impact of body fat, and 3) identify subpopulations that may receive the greatest benefit from higher flavonoid intakes in participants of the Danish Diet, Cancer, and Health Study followed up for 23 y.
Methods:
Cross-sectional associations between baseline flavonoid intake, estimated using FFQs and the Phenol Explorer database, and body fat, estimated by bioelectrical impedance, were assessed using multivariable-Adjusted linear regression models. Nonlinear associations between flavonoid intake and incident diabetes …
Musculoskeletal Responses To Exercise Plus Nutrition In Men With Prostate Cancer On Androgen Deprivation: A 12-Month Rct, Jack Dalla Via, Patrick J. Owen, Robin M. Daly, Niamh L. Mundell, Patricia M. Livingston, Timo Rantalainen, Stephen J. Foulkes, Jeremy L. Millar, Declan G. Murphy, Steve F. Fraser
Musculoskeletal Responses To Exercise Plus Nutrition In Men With Prostate Cancer On Androgen Deprivation: A 12-Month Rct, Jack Dalla Via, Patrick J. Owen, Robin M. Daly, Niamh L. Mundell, Patricia M. Livingston, Timo Rantalainen, Stephen J. Foulkes, Jeremy L. Millar, Declan G. Murphy, Steve F. Fraser
Research outputs 2014 to 2021
Purpose:
Androgen deprivation therapy (ADT) for prostate cancer has multiple adverse effects on musculoskeletal health. This 12-month randomized controlled trial aimed to assess the effects of multicomponent exercise training combined with whey protein, calcium and vitamin D supplementation on bone mineral density (BMD), structure and strength, body composition, muscle strength, and physical function in ADT-treated men.
Methods:
Seventy ADT-treated men were randomized to exercise plus supplementation (Ex + Suppl; n = 34) or usual care (control; n = 36). Ex + Suppl involved thrice weekly progressive resistance training plus weight-bearing impact exercise with daily multinutrient supplementation. Primary outcomes were DXA …
Healthy Eating And Physical Activity Among New Graduate Nurses: A Qualitative Study Of Barriers And Enablers During Their First Year Of Clinical Practice, Elizabeth Brogan, Chris Rossiter, Christine Duffield, Elizabeth Denney-Wilson
Healthy Eating And Physical Activity Among New Graduate Nurses: A Qualitative Study Of Barriers And Enablers During Their First Year Of Clinical Practice, Elizabeth Brogan, Chris Rossiter, Christine Duffield, Elizabeth Denney-Wilson
Research outputs 2014 to 2021
Background: New graduate nurses entering the workforce experience numerous barriers to maintaining a healthy lifestyle including shift work, the high cost of healthy foods at the workplace and high levels of exhaustion which reduce motivation to participate in regular physical activity. Research has documented unhealthy lifestyles among nurses across the profession. However, few studies focus on graduates' experiences during their transition into their careers. Aim: To investigate the barriers and enablers to healthy eating and participation in physical activity for new graduate nurses during their first year of clinical practice, and to explore attitudes to participation in workplace health promotion …
Early Gestational Profiling Of Oxidative Stress And Angiogenic Growth Mediators As Predictive, Preventive And Personalised (3p) Medical Approach To Identify Suboptimal Health Pregnant Mothers Likely To Develop Preeclampsia, Enoch O. Anto, David A. Coall, Otchere Addai-Mensah, Yaw Amo Wiafe, William K. B. A. Owiredu, Christian Obirikorang, Max E. Annani-Akollor, Eric Adua, Augustine Tawiah, Emmanuel Acheampong, Evans Adu Asamoah, Xueqing Wang, Stephen Opoku, Derick Kyei Boakye, Haifeng Hou, Youxin Wang, Wei Wang
Early Gestational Profiling Of Oxidative Stress And Angiogenic Growth Mediators As Predictive, Preventive And Personalised (3p) Medical Approach To Identify Suboptimal Health Pregnant Mothers Likely To Develop Preeclampsia, Enoch O. Anto, David A. Coall, Otchere Addai-Mensah, Yaw Amo Wiafe, William K. B. A. Owiredu, Christian Obirikorang, Max E. Annani-Akollor, Eric Adua, Augustine Tawiah, Emmanuel Acheampong, Evans Adu Asamoah, Xueqing Wang, Stephen Opoku, Derick Kyei Boakye, Haifeng Hou, Youxin Wang, Wei Wang
Research outputs 2014 to 2021
Pregnant women, particularly in developing countries are facing a huge burden of preeclampsia (PE) leading to high morbidity and mortality rates. This is due to delayed diagnosis and unrecognised early targeted preventive measures. Adapting innovative solutions via shifting from delayed to early diagnosis of PE in the context of predictive diagnosis, targeted prevention and personalisation of medical care (PPPM/3 PM) is essential. The subjective assessment of suboptimal health status (SHS) and objective biomarkers of oxidative stress (OS) and angiogenic growth mediators (AGMs) could be used as new PPPM approach for PE; however, these factors have only been studied in isolation …
The Effect Of Specific Locomotor Experiences On Infants’ Avoidance Behaviour On Real And Water Cliffs, Carolina Burnay, Rita Cordovil, Chris Button, James L. Croft, Matthew Schofield, Joana Pereira, David I. Anderson
The Effect Of Specific Locomotor Experiences On Infants’ Avoidance Behaviour On Real And Water Cliffs, Carolina Burnay, Rita Cordovil, Chris Button, James L. Croft, Matthew Schofield, Joana Pereira, David I. Anderson
Research outputs 2014 to 2021
© 2020 John Wiley & Sons Ltd Infants’ avoidance of drop-offs has been described as an affordance learning that is not transferable between different locomotor postures. In addition, there is evidence that infants perceive and act similarly around real and water cliffs. This cross-sectional study investigated the effects of specific locomotor experiences on infants’ avoidance behaviour using the Real Cliff/Water Cliff paradigm. The experiments included 102 infants, 58 crawling, but pre-walking, infants (Mage = 11.57 months, SD = 1.65) with crawling experience ranging between 0.03 and 7.4 months (M = 2.16, SD = 1.71) and 44 walking infants (Mage = …
Assessing Procedural Pain In Infants: A Feasibility Study Evaluating A Point-Of-Care Mobile Solution Based On Automated Facial Analysis, Kreshnik Hoti, Paola Teresa Chivers, Jeffery David Hughes
Assessing Procedural Pain In Infants: A Feasibility Study Evaluating A Point-Of-Care Mobile Solution Based On Automated Facial Analysis, Kreshnik Hoti, Paola Teresa Chivers, Jeffery David Hughes
Research outputs 2014 to 2021
BACKGROUND: The management of procedural pain in infants is suboptimal, in part, compounded by the scarcity of a simple, accurate, and reliable method of assessing such pain. In this study, we aimed to evaluate the psychometric properties of the PainChek Infant, a point-of-care mobile application that uses automated facial evaluation and analysis in the assessment of procedural pain in infants. METHODS: Video recordings of 40 infants were randomly chosen from a purposely assembled digital library of 410 children undergoing immunisation as part of their standard care in Prishtina, Kosovo, between April 4, 2017, and July 11, 2018. For each infant …
Exercise For Individuals With Bone Metastases: A Systematic Review, Sarah Weller, Nicolas H. Hart, Kate A. Bolam, Sami Mansfield, Daniel Santa Mina, Kerri M. Winters-Stone, Anna Campbell, Friederike Rosenberger, Joachim Wiskemann, Morten Quist, Prue Cormie, Jennifer Goulart, Kristin L. Campbell
Exercise For Individuals With Bone Metastases: A Systematic Review, Sarah Weller, Nicolas H. Hart, Kate A. Bolam, Sami Mansfield, Daniel Santa Mina, Kerri M. Winters-Stone, Anna Campbell, Friederike Rosenberger, Joachim Wiskemann, Morten Quist, Prue Cormie, Jennifer Goulart, Kristin L. Campbell
Research outputs 2014 to 2021
BACKGROUND: Exercise has the potential to improve physical function and quality of life in individuals with bone metastases but is often avoided due to safety concerns. This systematic review summarizes the safety, feasibility and efficacy of exercise in controlled trials that include individuals with bone metastases. METHODS: MEDLINE, Embase, Pubmed, CINAHL, PEDro and CENTRAL databases were searched to July 16, 2020. RESULTS: A total of 17 trials were included incorporating aerobic exercise, resistance exercise or soccer interventions. Few (n = 4, 0.5%) serious adverse events were attributed to exercise participation, with none related to bone metastases. Mixed efficacy results were …
Intra- And Inter-Tumoral Heterogeneity Of Liver Metastases In A Patient With Uveal Melanoma Revealed By Single-Cell Rna Sequencing, Weitao Lin, Aaron Beasley, Nima Mesbah Ardakani, Elena Denisenko, Leslie Calapre, Matthew Jones, Benjamin Woods, Lydia Warburton, Alistair R.R. Forrest, Elin S. Gray
Intra- And Inter-Tumoral Heterogeneity Of Liver Metastases In A Patient With Uveal Melanoma Revealed By Single-Cell Rna Sequencing, Weitao Lin, Aaron Beasley, Nima Mesbah Ardakani, Elena Denisenko, Leslie Calapre, Matthew Jones, Benjamin Woods, Lydia Warburton, Alistair R.R. Forrest, Elin S. Gray
Research outputs 2014 to 2021
Tumour heterogeneity is a major obstacle to the success of cancer treatment. An accurate understanding and recognition of tumour heterogeneity is critical in the clinical management of cancer patients. Here, we utilised single-cell RNA sequencing (scRNA-seq) to uncover the intra- and inter-tumoural heterogeneity of liver metastases from a patient with metastatic uveal melanoma. The two metastases analysed were largely infiltrated by non-cancerous cells with significant variability in the proportion of different cell types. Analysis of copy number variations (CNVs) showed gain of 8q and loss of 6q in both tumours, but loss of chromosome 3 was only detected in one …
Testing, Training, And Optimising Performance Of Track Cyclists: A Systematic Mapping Review, Antony M. Stadnyk, Franco M. Impellizzeri, Jamie Stanley, Paolo Menaspà, Katie M. Slattery
Testing, Training, And Optimising Performance Of Track Cyclists: A Systematic Mapping Review, Antony M. Stadnyk, Franco M. Impellizzeri, Jamie Stanley, Paolo Menaspà, Katie M. Slattery
Research outputs 2014 to 2021
BACKGROUND: Track cyclists must develop mental, physical, tactical and technical capabilities to achieve success at an elite level. Given the importance of these components in determining performance, it is of interest to understand the volume of evidence to support implementation in practice by coaches, practitioners, and athletes. OBJECTIVE: The aim of this study was to conduct a systematic mapping review to describe the current scale and density of research for testing, training and optimising performance in track cycling. METHODS: All publications involving track cyclist participants were reviewed from four databases (PubMed, SPORTDiscus, Academic Search Complete, Cochrane Library) plus additional sources. …
Association Between Vitamin K1 Intake And Mortality In The Danish Diet, Cancer, And Health Cohort, Claire R. Palmer, Jamie W. Bellinge, Frederik Dalgaard, Marc Sim, Kevin Murray, Emma Connolly, Lauren C. Blekkenhorst, Catherine P. Bondonno, Kevin D. Croft, Gunnar Gislason, Anne Tjønneland, Kim Overvad, Carl Schultz, Joshua R. Lewis, Jonathan M. Hodgson, Nicola P. Bondonno
Association Between Vitamin K1 Intake And Mortality In The Danish Diet, Cancer, And Health Cohort, Claire R. Palmer, Jamie W. Bellinge, Frederik Dalgaard, Marc Sim, Kevin Murray, Emma Connolly, Lauren C. Blekkenhorst, Catherine P. Bondonno, Kevin D. Croft, Gunnar Gislason, Anne Tjønneland, Kim Overvad, Carl Schultz, Joshua R. Lewis, Jonathan M. Hodgson, Nicola P. Bondonno
Research outputs 2014 to 2021
Reported associations between vitamin K and both all-cause and cause-specific mortality are conflicting. The 56,048 participants from the Danish Diet, Cancer, and Health prospective cohort study, with a median [IQR] age of 56 [52-60] years at entry and of whom 47.6% male, were followed for 23 years, with 14,083 reported deaths. Of these, 5015 deaths were CVD-related, and 6342 deaths were cancer-related. Intake of vitamin K (phylloquinone) was estimated from a food-frequency questionnaire (FFQ), and its relationship with mortality outcomes was investigated using Cox proportional hazards models. A moderate to high (87-192 µg/d) intake of vitamin K was associated with …
Uptake Of Health Services By Youth Living With Hiv: A Focused Ethnography, Maggie Zgambo, Diana Arabiat, Deb Ireson
Uptake Of Health Services By Youth Living With Hiv: A Focused Ethnography, Maggie Zgambo, Diana Arabiat, Deb Ireson
Research outputs 2014 to 2021
Background:
Although several programs have been initiated to increase the uptake of health services amongst youth living with human immunodeficiency virus in the world, disparities in access to these care services still exist.
Aim:
This study aimed to explore the experiences of young people as they attend the human immunodeficiency virus clinic and to identify factors affecting their uptake of health services in southern Malawi.
Methods:
A focused ethnography was conducted to collect data from 20 youths living with human immunodeficiency virus and aged between 15 and 24 years through one-on-one in-depth interviews and casual observations. The interviews data were …
Dental Professionals’ Perspectives Working With Aboriginal Children In Western Australia: A Qualitative Study, A. Durey, Lydia Hearn, S. Lund, M. O’Grady, L. Slack-Smith
Dental Professionals’ Perspectives Working With Aboriginal Children In Western Australia: A Qualitative Study, A. Durey, Lydia Hearn, S. Lund, M. O’Grady, L. Slack-Smith
Research outputs 2014 to 2021
Background:
The disproportionate burden of oral disease in Aboriginal children and the issues in accessing mainstream dental services are well documented. Yet little is known about dental professionals’ perspectives in providing oral care for Aboriginal children. This paper presents findings from a study exploring such perspectives.
Methods:
Semi-structured interviews were carried out in Western Australia following purposive sampling of non-Aboriginal dentists, dental clinic assistants (dental nurses) and oral health therapists/dental hygienists. Interviews were recorded, transcribed and analysed guided by grounded theory for key themes related to the topic.
Results:
Findings included a service delivery model sometimes unresponsive to Aboriginal families’ …
Study Protocol For A Prospective Process Evaluation Of A Culturally Secure Rehabilitation Programme For Aboriginal Australians After Brain Injury: The Healing Right Way Project, Rachel Skoss, Jane White, Mandy J. Stanley, Melanie Robinson, Sandra Thompson, Elizabeth Armstrong, Judith M. Katzenellenbogen
Study Protocol For A Prospective Process Evaluation Of A Culturally Secure Rehabilitation Programme For Aboriginal Australians After Brain Injury: The Healing Right Way Project, Rachel Skoss, Jane White, Mandy J. Stanley, Melanie Robinson, Sandra Thompson, Elizabeth Armstrong, Judith M. Katzenellenbogen
Research outputs 2014 to 2021
INTRODUCTION: Aboriginal and Torres Strait Islander (hereafter respectfully referred to as Aboriginal) people are Australia's First Peoples, having the longest continuous culture in the world and deep spiritual connections with ancestral land. Improvements in their health and well-being is a major policy goal of Australian governments, as the legacy of colonisation and disruption of cultural practices contribute to major health challenges. Lack of culturally secure services impacts participation of Aboriginal people in health services. Aboriginal people with a brain injury typically experience poor access to rehabilitation and support following hospital discharge. 'Healing Right Way' (HRW) is a randomised control trial …
Acute Effect Of Particulate Matter Pollution On Hospital Admissions For Cause-Specific Respiratory Diseases Among Patients With And Without Type 2 Diabetes In Beijing, China, From 2014 To 2020, Mengmeng Liu, Zhiwei Li, Feng Lu, Moning Guo, Lixin Tao, Mengyang Liu, Yue Liu, Aklilu Deginet, Yaoyu Hu, Yutong Li, Mengqiu Wu, Yanxia Luo, Xiaonan Wang, Xinghua Yang, Bo Gao, Xiuhua Guo, Xiangtong Liu
Acute Effect Of Particulate Matter Pollution On Hospital Admissions For Cause-Specific Respiratory Diseases Among Patients With And Without Type 2 Diabetes In Beijing, China, From 2014 To 2020, Mengmeng Liu, Zhiwei Li, Feng Lu, Moning Guo, Lixin Tao, Mengyang Liu, Yue Liu, Aklilu Deginet, Yaoyu Hu, Yutong Li, Mengqiu Wu, Yanxia Luo, Xiaonan Wang, Xinghua Yang, Bo Gao, Xiuhua Guo, Xiangtong Liu
Research outputs 2014 to 2021
BACKGROUND: Scientific studies have identified various adverse effects of particulate matter (PM) on respiratory disease (RD) and type 2 diabetes (T2D). However, whether short-term exposure to PM triggers the onset of RD with T2D, compared with RD without T2D, has not been elucidated. METHODS: A two-stage time-series study was conducted to evaluate the acute adverse effects of PM on admission for RD and for RD with and without T2D in Beijing, China, from 2014 to 2020. District-specific effects of PM and PM were estimated using the over-dispersed Poisson generalized addictive model after adjusting for weather conditions, day of the week, …
A Comparison Of Manual And Automatic Force-Onset Identification Methodologies And Their Effect On Force-Time Characteristics In The Isometric Midthigh Pull, Stuart N. Guppy, Claire J. Brady, Yosuke Kotani, Shannon Connolly, Paul Comfort, Jason P. Lake, G. Gregory Haff
A Comparison Of Manual And Automatic Force-Onset Identification Methodologies And Their Effect On Force-Time Characteristics In The Isometric Midthigh Pull, Stuart N. Guppy, Claire J. Brady, Yosuke Kotani, Shannon Connolly, Paul Comfort, Jason P. Lake, G. Gregory Haff
Research outputs 2014 to 2021
The aim of this study was to assess the agreement of three different automated methods of identifying force-onset (40 N, 5 SDs, and 3 SDs) with manual identification, during the isometric mid-thigh pull (IMTP). Fourteen resistance-trained participants with > 6 months experience training with the power clean volunteered to take part. After three familiarisation sessions, the participants performed five maximal IMTPs separated by 1 min of rest. Fixed bias was found between 40 N and manual identification for time at force-onset. No proportional bias was present between manual identification and any automated threshold. Fixed bias between manual identification and automated was …
Genetic Analysis Of Endometriosis And Depression Identifies Shared Loci And Implicates Causal Links With Gastric Mucosa Abnormality, Emmanuel Adewuyi, Divya Mehta, Yadav Sapkota, Asa Auta, Kosuke Yoshihara, Mette Nyegaard, Lyn R. Griffiths, Grant W. Montgomery, Daniel I. Chasman, Dale R. Nyholt
Genetic Analysis Of Endometriosis And Depression Identifies Shared Loci And Implicates Causal Links With Gastric Mucosa Abnormality, Emmanuel Adewuyi, Divya Mehta, Yadav Sapkota, Asa Auta, Kosuke Yoshihara, Mette Nyegaard, Lyn R. Griffiths, Grant W. Montgomery, Daniel I. Chasman, Dale R. Nyholt
Research outputs 2014 to 2021
Evidence from observational studies indicates that endometriosis and depression often co-occur. However, conflicting evidence exists, and the etiology as well as biological mechanisms underlying their comorbidity remain unknown. Utilizing genome-wide association study (GWAS) data, we comprehensively assessed the relationship between endometriosis and depression. Single nucleotide polymorphism effect concordance analysis (SECA) found a significant genetic overlap between endometriosis and depression (PFsig-permuted = 9.99 × 10−4). Linkage disequilibrium score regression (LDSC) analysis estimated a positive and highly significant genetic correlation between the two traits (rG = 0.27, P = 8.85 × 10−27). A meta-analysis of endometriosis and depression GWAS (sample size = …
Variation Of Igg N-Linked Glycosylation Profile In Diabetic Retinopathy, Zhiyuan Wu, Huiying Pan, Di Liu, Di Zhou, Lixin Tao, Jie Zhang, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo
Variation Of Igg N-Linked Glycosylation Profile In Diabetic Retinopathy, Zhiyuan Wu, Huiying Pan, Di Liu, Di Zhou, Lixin Tao, Jie Zhang, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo
Research outputs 2014 to 2021
Background:
The relationship of immunoglobulin G (IgG) glycosylation with diabetes and diabetic nephropathy has been reported, but its role in diabetic retinopathy (DR) remains unclear. We aimed to investigate and validate the association of IgG glycosylation with DR.
Methods:
We analyzed the IgG N-linked glycosylation profile and primarily selected candidate glycans by lasso (least absolute shrinkage and selection operator) regression analysis in the discovery population. The findings were validated in the replication population using a binary logistics model. The association between the significant glycosylation panel and clinical features was illustrated with Spearman's coefficient. The results were confirmed by sensitivity analyses. …
Online Learning And Teaching Approaches Used In Midwifery Programs: A Scoping Review, Terri Downer, Michelle Gray, Tanya Capper
Online Learning And Teaching Approaches Used In Midwifery Programs: A Scoping Review, Terri Downer, Michelle Gray, Tanya Capper
Research outputs 2014 to 2021
Objective: The objective of this scoping review was to map and identify existing literature that described online learning and teaching approaches used in midwifery education. Design: An extensive search of multiple databases and gray literature was undertaken following the JBI standards, using predefined selection criteria and following the PRISMA guidelines. Methods: This scoping review included studies published in English between 2010 and 2020 that explored the online approaches to learning and teaching for undergraduate midwifery students. The articles were reviewed by three reviewers and content analysis was undertaken. Results: Twenty-seven articles were included in the review. Results suggest that student …
Language Abilities In Children Born To Mothers Diagnosed With Diabetes: A Systematic Review And Meta-Analysis, Diana Arabiat, Mohammad Al Jabery, Mark Jenkins, Vivien Kemp, Lisa Whitehead, Gary Adams
Language Abilities In Children Born To Mothers Diagnosed With Diabetes: A Systematic Review And Meta-Analysis, Diana Arabiat, Mohammad Al Jabery, Mark Jenkins, Vivien Kemp, Lisa Whitehead, Gary Adams
Research outputs 2014 to 2021
Background:
This meta-analysis reviewed and synthesized the available evidence on the association between intrauterine exposure to maternal diabetes and language abilities in children.
MEDLINE/PubMed, EMBASE, PsycINFO, Proquest Dissertations and Theses Global, and Google Scholar databases were searched through December 2020. Studies were systematically searched, and effect sizes were calculated using random effects models.
Results:
Twelve studies were identified for inclusion in this review, however, only 10 were included in the meta-analysis. Sample size ranged from 9 to 115 participants in the diabetes group and 28 to 8192 in the control and aged around 3 years. The pooled results of the …
Win, Draw, Or Lose? Global Positioning System-Based Variables’ Effect On The Match Outcome: A Full-Season Study On An Iranian Professional Soccer Team, Hadi Nobari, Norbert Keshish Banoocy, Rafael Oliveira, Jorge Pérez-Gómez
Win, Draw, Or Lose? Global Positioning System-Based Variables’ Effect On The Match Outcome: A Full-Season Study On An Iranian Professional Soccer Team, Hadi Nobari, Norbert Keshish Banoocy, Rafael Oliveira, Jorge Pérez-Gómez
Research outputs 2014 to 2021
The aim of the study was to determine the between-match and between-halves match variability of various Global Positioning System (GPS) variables and metabolic power average (MPA) in competitions, based on the match results obtained by professional soccer players over a full season. Observations on individual match performance measures were undertaken on thirteen outfield players competing in the Iranian Premier League. The measures selected for analysis included total duration, accelerations in zones (AccZ1, 2, and 3), decelerations in zones (DecZ1, 2, and 3), and MPA collected by the Wearable Inertial Measurement Unit (WIMU). The GPS manufacturer set the thresholds for the …
Supporting Health Literacy In Adolescent Populations: Distinguishing Pedagogies For Sun Safety Education In Schools, Donna Barwood
Supporting Health Literacy In Adolescent Populations: Distinguishing Pedagogies For Sun Safety Education In Schools, Donna Barwood
Research outputs 2014 to 2021
Purpose: The aim of this paper is to distinguish pedagogies supporting critical health literacy development in adolescent populations. Specifically, for sun safety education in schools. Design/methodology/approach: The paper draws on an exploratory intrinsic case study design to qualitatively examine the learning conditions that Pre-Service Teachers' (PsTs) mobilise to advance Health Literary (HL) in learning activities. Findings: This paper presents data that shows the different ways thirty Pre-Service Teachers (PsTs) in Western Australia conceptualise HL in sun safety education for Year 7 students (12–13 years old). Examination of three consecutive lesson plans categorised learning activities (n = 444) according to HL …