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Full-Text Articles in Medicine and Health Sciences

Treatment Integrity And Differentiation In The Very Early Rehabilitation In Speech (Verse) Trial, Emily Brogan, Natalie Ciccone, Erin Godecke Jan 2023

Treatment Integrity And Differentiation In The Very Early Rehabilitation In Speech (Verse) Trial, Emily Brogan, Natalie Ciccone, Erin Godecke

Research outputs 2014 to 2021

Background:

Key elements of treatment fidelity include treatment integrity (adherence to the treatment protocol) and treatment differentiation (the difference in treatment ingredients in the control and intervention groups). The Very Early Rehabilitation in SpEech (VERSE) trial established treatment fidelity at the macro level for key components of therapy.

Aims:

To complete a detailed analysis of treatment integrity and differentiation at the utterance level of a therapeutic interaction.

Methods:

This was an observational study of therapy videos collected as part of the VERSE trial. Participants were people with aphasia in the very early phase of recovery post stroke (n = 44) …


Countermovement Jump And Squat Jump Force-Time Curve Analysis In Control And Fatigue Conditions, Steven Hughes, John Warmenhoven, G. Gregory Haff, Dale W. Chapman, Sophia Nimphius Oct 2022

Countermovement Jump And Squat Jump Force-Time Curve Analysis In Control And Fatigue Conditions, Steven Hughes, John Warmenhoven, G. Gregory Haff, Dale W. Chapman, Sophia Nimphius

Research outputs 2014 to 2021

This study aimed to reanalyze previously published discrete force data from countermovement jumps (CMJs) and squat jumps (SJs) using statistical parametric mapping (SPM), a statistical method that enables analysis of data in its native, complete state. Statistical parametric mapping analysis of 1-dimensional (1D) force-time curves was compared with previous zero-dimensional (0D) analysis of peak force to assess sensitivity of 1D analysis. Thirty-two subjects completed CMJs and SJs at baseline, 15 minutes, 1, 24, and 48 hours following fatigue and control conditions in a pseudo random cross-over design. Absolute (CMJABS/SJABS) and time-normalized (CMJNORM/SJNORM) …


Myokine Expression And Tumor-Suppressive Effect Of Serum Following 12 Weeks Of Exercise In Prostate Cancer Patients On Adt, Jin-Soo Kim, Rebekah Louise Wilson, Dennis Taaffe, Daniel A. Galvao, Elin S. Gray, Robert Newton Jan 2022

Myokine Expression And Tumor-Suppressive Effect Of Serum Following 12 Weeks Of Exercise In Prostate Cancer Patients On Adt, Jin-Soo Kim, Rebekah Louise Wilson, Dennis Taaffe, Daniel A. Galvao, Elin S. Gray, Robert Newton

Research outputs 2014 to 2021

Purpose:

Although several mechanisms have been proposed for the tumor-suppressive effect of exercise, little attention has been given to myokines, even though skeletal muscle is heavily recruited during exercise resulting in myokine surges. We measured resting serum myokine levels before and after an exercise-based intervention and the effect of this serum on prostate cancer cell growth.

Methods:

Ten prostate cancer patients undertaking androgen deprivation therapy (age, 73.3 ± 5.6 yr) undertook a 12-wk exercise-based intervention including supervised resistance training, self-directed aerobic exercise, and protein supplementation. Body composition was assessed by dual-energy x-ray absorptiometry and muscle strength by the one-repetition maximum …


Derivation Of A Prototype Asthma Attack Risk Scale Centred On Blood Eosinophils And Exhaled Nitric Oxide, Simon Couillard, Annette Laugerud, Maisha Jabeen, Sanjay Ramakrishnan, James Melhorn, Timothy Hinks, Ian Pavord Jan 2022

Derivation Of A Prototype Asthma Attack Risk Scale Centred On Blood Eosinophils And Exhaled Nitric Oxide, Simon Couillard, Annette Laugerud, Maisha Jabeen, Sanjay Ramakrishnan, James Melhorn, Timothy Hinks, Ian Pavord

Research outputs 2014 to 2021

Reduction of the risk of asthma attacks is a major goal of current asthma management. We propose to derive a risk scale predicting asthma attacks based on the blood eosinophil count and exhaled nitric oxide. Biomarker-stratified trial-level attack rates were extracted and pooled from the control arms of the Novel START, CAPTAIN, QUEST, Benralizumab Phase 2b, PATHWAY, STRATOS 1-2 and DREAM trials (n=3051). These were used to derive rate ratios and the predicted asthma attack rate for different patient groups. The resultant prototype risk scale shows potential to predict asthma attacks, which may be prevented by anti-inflammatory treatment.


Factors Influencing The Development And Implementation Of Nurse Practitioner Candidacy Programs: A Scoping Review, Lisa Whitehead, Diane E. Twigg, Rebecca Carman, Courtney Glass, Helena Halton, Christine M. Duffield Jan 2022

Factors Influencing The Development And Implementation Of Nurse Practitioner Candidacy Programs: A Scoping Review, Lisa Whitehead, Diane E. Twigg, Rebecca Carman, Courtney Glass, Helena Halton, Christine M. Duffield

Research outputs 2014 to 2021

Background

To meet the growing needs of a diverse population, it is critical that healthcare service provision is underpinned by innovative, cost-effective, and sustainable services and solutions. The role of the nurse practitioner creates an opportunity to meet the increasing demands of complex care and enables greater access to high quality care. Understanding how best to support nurse practitioner candidates to develop into the nurse practitioner role will create greater opportunities to transform service delivery and improve healthcare outcomes.

Aim

To identify key factors that support and positively impact the implementation of nurse practitioner candidacy programs and candidate experiences.

Methods …


Combination Fixed-Dose Β Agonist And Steroid Inhaler As Required For Adults Or Children With Mild Asthma: A Cochrane Systematic Review, Iain Crossingham, Sally Turner, Sanjay Ramakrishnan, Anastasia Fries, Matthew Gowell, Farhat Yasmin, Rebekah Richardson, Philip Webb, Emily O'Boyle, Timothy S. C. Hinks Jan 2022

Combination Fixed-Dose Β Agonist And Steroid Inhaler As Required For Adults Or Children With Mild Asthma: A Cochrane Systematic Review, Iain Crossingham, Sally Turner, Sanjay Ramakrishnan, Anastasia Fries, Matthew Gowell, Farhat Yasmin, Rebekah Richardson, Philip Webb, Emily O'Boyle, Timothy S. C. Hinks

Research outputs 2014 to 2021

Background:

In people with mild asthma poor adherence to regular therapy is common and increases the risk of exacerbations, morbidity and mortality. The use of fixed-dose combination inhalers containing an inhaled corticosteroid (ICS) and a fast-acting β2-agonist (FABA) is established in moderate asthma, but they may also have potential utility in mild asthma.

Objectives:

To evaluate the efficacy and safety of single combined FABA/ICS inhaler only used as needed in people with mild asthma. Design and setting: Cochrane meta-analysis of available trial data.

Participants:

Children aged 12+ and adults with mild asthma. Search methods: We searched the Cochrane Airways Trials …


Breech Presentation Management: A Critical Review Of Leading Clinical Practice Guidelines, Sara Morris, Sadie Geraghty, Deborah Sundin Jan 2022

Breech Presentation Management: A Critical Review Of Leading Clinical Practice Guidelines, Sara Morris, Sadie Geraghty, Deborah Sundin

Research outputs 2014 to 2021

Problem

Clinical practice guidelines are designed to guide clinicians and consumers of maternity services in clinical decision making, but recommendations are often consensus based and differ greatly between leading organisations.

Background

Breech birth is a divisive clinical issue, however vaginal breech births continue to occur despite a globally high caesarean section rate for breech presenting fetuses. Inconsistencies are known to exist between clinical practice guidelines relating to the management of breech presentation.

Aim

The aim of this review was to critically evaluate and compare leading obstetric clinical practice guidelines related to the management of breech presenting fetuses.

Methods

Leading obstetric …


Patients’ Experiences Of A Communication Enhanced Environment Model On An Acute/Slow Stream Rehabilitation And A Rehabilitation Ward Following Stroke: A Qualitative Description Approach, Sarah D'Souza, Deborah J. Hersh, Erin Godecke, Natalie Ciccone, Heidi Janssen, Elizabeth Armstrong Jan 2022

Patients’ Experiences Of A Communication Enhanced Environment Model On An Acute/Slow Stream Rehabilitation And A Rehabilitation Ward Following Stroke: A Qualitative Description Approach, Sarah D'Souza, Deborah J. Hersh, Erin Godecke, Natalie Ciccone, Heidi Janssen, Elizabeth Armstrong

Research outputs 2014 to 2021

Background

Patients in hospital following stroke express a desire to continue therapy tasks outside of treatment activities. However, they commonly describe experiences of boredom and inactivity. An enriched environment aims to provide opportunities for physical, cognitive and social activity and informed the development of a Communication Enhanced Environment (CEE) model to promote patient engagement in language activities.

Purpose

Explore patient perceptions of a CEE model, and barriers and facilitators to engagement in the model.

Methods

A qualitative description study from a larger project that implemented a CEE model into acute and rehabilitation private hospital wards in Western Australia. Semi-structured interviews …


It Cannot Happen, Never: A Qualitative Study Exploring Youth Views On Disclosure Of Hiv Diagnosis To Their Sexual Partners In Southern Malawi, Maggie Zgambo, Diana Arabiat, Deborah M. Ireson Dr Dec 2021

It Cannot Happen, Never: A Qualitative Study Exploring Youth Views On Disclosure Of Hiv Diagnosis To Their Sexual Partners In Southern Malawi, Maggie Zgambo, Diana Arabiat, Deborah M. Ireson Dr

Research outputs 2014 to 2021

With the availability of antiretroviral therapy, more children living with HIV live longer than before and grow into young adulthood. This study examined the concerns of youth about disclosure of an HIV diagnosis to their sexual partners and attempted to gain an understanding of their HIV status disclosure experiences, views, and plans. A focused ethnography was undertaken. Using semi-structured interviews, data were collected from 20 youth between the ages of 15 and 24 years who were attending an HIV clinic. The findings highlight that youth generally struggled to disclose their HIV status to their sexual partners. The most frequent reasons …


A Multifaceted Approach Increased Staff Confidence To Develop Outside Of School Hours Care As A Health Promoting Setting, Karen Forde, Leesa Costello, Amanda Devine, Ros Sambell, Ruth Wallace Dec 2021

A Multifaceted Approach Increased Staff Confidence To Develop Outside Of School Hours Care As A Health Promoting Setting, Karen Forde, Leesa Costello, Amanda Devine, Ros Sambell, Ruth Wallace

Research outputs 2014 to 2021

Background:

Outside-of-school-hours-care (OSHC) services are well positioned to influence the health behaviours of 489, 800 Australian children, and are an important setting for health promotion given the current rates of childhood overweight and obesity and associated health risks. OSHC Professionals are ideally placed to become positive influencers in this setting, although they may require training and support to confidently perform this role. This study piloted a multifaceted intervention strategy to increase OSHC Professional’s confidence and competencies, to support a health promoting OSHC environment with a nutrition and physical activity focus.

Methods:

A mixed methods approach was used. Nineteen OSHC Professionals …


Host Defence Peptides In Diabetes Mellitus Type 2 Patients With Periodontal Disease. A Systematic Review, Muhammad Saad Shaikh, Muhammad Sohail Zafar, Farhan Saleem, Ahmad Alnazzawi, Mohid Abrar Lone, Syed Jawad Ali Bukhari, Zohaib Khurshid Dec 2021

Host Defence Peptides In Diabetes Mellitus Type 2 Patients With Periodontal Disease. A Systematic Review, Muhammad Saad Shaikh, Muhammad Sohail Zafar, Farhan Saleem, Ahmad Alnazzawi, Mohid Abrar Lone, Syed Jawad Ali Bukhari, Zohaib Khurshid

Research outputs 2014 to 2021

The aim of the study was to critically assess and review the latest evidence relating the associations between host defence peptides (HDPs), periodontal diseases (PD) and diabetes mellitus type 2 (DM2). To explore studies on HDPs, periodontal disease, and DM2, researchers utilised specific key phrases to search the electronic databases PubMed (National Library of Medicine), Embase (Ovid), Medline (EBSCO), and Dentistry and Oral Sciences (EBSCO). Quality assessment was conducted by means of the Newcastle Ottawa scale and the Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) tool. Following a thorough screening process, a total of 12 papers (4 case‐control, 6 …


Using Imputation To Provide Harmonized Longitudinal Measures Of Cognition Across Aibl And Adni, Rosita Shishegar, Timothy Cox, David Rolls, Pierrick Bourgeat, Vincent Doré, Fiona Lamb, Joanne Robertson, Simon M. Laws, Tenielle Porter, Jurgen Fripp, Duygu Tosun, Paul Maruff, Greg Savage, Christopher C. Rowe, Colin L. Masters, Michael W. Weiner, Victor L. Villemagne, Samantha C. Burnham Dec 2021

Using Imputation To Provide Harmonized Longitudinal Measures Of Cognition Across Aibl And Adni, Rosita Shishegar, Timothy Cox, David Rolls, Pierrick Bourgeat, Vincent Doré, Fiona Lamb, Joanne Robertson, Simon M. Laws, Tenielle Porter, Jurgen Fripp, Duygu Tosun, Paul Maruff, Greg Savage, Christopher C. Rowe, Colin L. Masters, Michael W. Weiner, Victor L. Villemagne, Samantha C. Burnham

Research outputs 2014 to 2021

To improve understanding of Alzheimer’s disease, large observational studies are needed to increase power for more nuanced analyses. Combining data across existing observational studies represents one solution. However, the disparity of such datasets makes this a non-trivial task. Here, a machine learning approach was applied to impute longitudinal neuropsychological test scores across two observational studies, namely the Australian Imaging, Biomarkers and Lifestyle Study (AIBL) and the Alzheimer's Disease Neuroimaging Initiative (ADNI) providing an overall harmonised dataset. MissForest, a machine learning algorithm, capitalises on the underlying structure and relationships of data to impute test scores not measured in one study aligning …


Running Performance Of Male Versus Female Players In Australian Football Matches: A Systematic Review, Christopher Wing, Nicolas H. Hart, Callum Mccaskie, Petar Djanis, Fadi Ma’Ayah, Kazunori Nosaka Dec 2021

Running Performance Of Male Versus Female Players In Australian Football Matches: A Systematic Review, Christopher Wing, Nicolas H. Hart, Callum Mccaskie, Petar Djanis, Fadi Ma’Ayah, Kazunori Nosaka

Research outputs 2014 to 2021

Background:

Australian Football is a fast paced, intermittent sport, played by both male and female populations. The aim of this systematic review was to compare male and female Australian Football players, competing at elite and sub-elite levels, for running performance during Australian Football matches based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).

Methods:

Medline, SPORTDiscus, and Web of Science searches, using search terms inclusive of Australian Football, movement demands and microsensor technology, returned 2535 potential manuscripts, of which 33 were included in the final analyses.

Results:

Results indicated that male athletes performed approximately twice the total …


Eccentric-Only Versus Concentric-Only Resistance Training Effects On Biochemical And Physiological Parameters In Patients With Type 2 Diabetes, Christine Kudiarasu, Wafina Rohadhia, Yoshihiro Katsura, Tomoko Koeda, Favil Singh, Kazunori Nosaka Dec 2021

Eccentric-Only Versus Concentric-Only Resistance Training Effects On Biochemical And Physiological Parameters In Patients With Type 2 Diabetes, Christine Kudiarasu, Wafina Rohadhia, Yoshihiro Katsura, Tomoko Koeda, Favil Singh, Kazunori Nosaka

Research outputs 2014 to 2021

Background:

The benefits of resistance training for patients with type 2 diabetes (T2D) are well documented; however, the effects of exercise with different muscle contraction types such as eccentric versus concentric contractions on physiological outcomes for this population are not clear. This study compared eccentric-only (ECC) and concentric-only resistance training (CON) to test the hypothesis that ECC would be superior to CON to improve insulin sensitivity, lipid profile, body composition, muscle strength and physical function of patients with T2D.

Methods:

Adults with T2D (50–79 years) were allocated to the ECC (n = 9) or CON group (n = 9). Resistance …


Uptake Of Health Services By Youth Living With Hiv: A Focused Ethnography, Maggie Zgambo, Diana Arabiat, Deb Ireson Sep 2021

Uptake Of Health Services By Youth Living With Hiv: A Focused Ethnography, Maggie Zgambo, Diana Arabiat, Deb Ireson

Research outputs 2014 to 2021

Background:

Although several programs have been initiated to increase the uptake of health services amongst youth living with human immunodeficiency virus in the world, disparities in access to these care services still exist.

Aim:

This study aimed to explore the experiences of young people as they attend the human immunodeficiency virus clinic and to identify factors affecting their uptake of health services in southern Malawi.

Methods:

A focused ethnography was conducted to collect data from 20 youths living with human immunodeficiency virus and aged between 15 and 24 years through one-on-one in-depth interviews and casual observations. The interviews data were …


A Comparison Of Manual And Automatic Force-Onset Identification Methodologies And Their Effect On Force-Time Characteristics In The Isometric Midthigh Pull, Stuart N. Guppy, Claire J. Brady, Yosuke Kotani, Shannon Connolly, Paul Comfort, Jason P. Lake, G. Gregory Haff Sep 2021

A Comparison Of Manual And Automatic Force-Onset Identification Methodologies And Their Effect On Force-Time Characteristics In The Isometric Midthigh Pull, Stuart N. Guppy, Claire J. Brady, Yosuke Kotani, Shannon Connolly, Paul Comfort, Jason P. Lake, G. Gregory Haff

Research outputs 2014 to 2021

The aim of this study was to assess the agreement of three different automated methods of identifying force-onset (40 N, 5 SDs, and 3 SDs) with manual identification, during the isometric mid-thigh pull (IMTP). Fourteen resistance-trained participants with > 6 months experience training with the power clean volunteered to take part. After three familiarisation sessions, the participants performed five maximal IMTPs separated by 1 min of rest. Fixed bias was found between 40 N and manual identification for time at force-onset. No proportional bias was present between manual identification and any automated threshold. Fixed bias between manual identification and automated was …


Variation Of Igg N-Linked Glycosylation Profile In Diabetic Retinopathy, Zhiyuan Wu, Huiying Pan, Di Liu, Di Zhou, Lixin Tao, Jie Zhang, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo Aug 2021

Variation Of Igg N-Linked Glycosylation Profile In Diabetic Retinopathy, Zhiyuan Wu, Huiying Pan, Di Liu, Di Zhou, Lixin Tao, Jie Zhang, Xiaonan Wang, Xia Li, Youxin Wang, Wei Wang, Xiuhua Guo

Research outputs 2014 to 2021

Background:

The relationship of immunoglobulin G (IgG) glycosylation with diabetes and diabetic nephropathy has been reported, but its role in diabetic retinopathy (DR) remains unclear. We aimed to investigate and validate the association of IgG glycosylation with DR.

Methods:

We analyzed the IgG N-linked glycosylation profile and primarily selected candidate glycans by lasso (least absolute shrinkage and selection operator) regression analysis in the discovery population. The findings were validated in the replication population using a binary logistics model. The association between the significant glycosylation panel and clinical features was illustrated with Spearman's coefficient. The results were confirmed by sensitivity analyses. …


Win, Draw, Or Lose? Global Positioning System-Based Variables’ Effect On The Match Outcome: A Full-Season Study On An Iranian Professional Soccer Team, Hadi Nobari, Norbert Keshish Banoocy, Rafael Oliveira, Jorge Pérez-Gómez Aug 2021

Win, Draw, Or Lose? Global Positioning System-Based Variables’ Effect On The Match Outcome: A Full-Season Study On An Iranian Professional Soccer Team, Hadi Nobari, Norbert Keshish Banoocy, Rafael Oliveira, Jorge Pérez-Gómez

Research outputs 2014 to 2021

The aim of the study was to determine the between-match and between-halves match variability of various Global Positioning System (GPS) variables and metabolic power average (MPA) in competitions, based on the match results obtained by professional soccer players over a full season. Observations on individual match performance measures were undertaken on thirteen outfield players competing in the Iranian Premier League. The measures selected for analysis included total duration, accelerations in zones (AccZ1, 2, and 3), decelerations in zones (DecZ1, 2, and 3), and MPA collected by the Wearable Inertial Measurement Unit (WIMU). The GPS manufacturer set the thresholds for the …


Construct Validity And Invariance Assessment Of The Social Impacts Of Occupational Heat Stress Scale (Siohss) Among Ghanaian Mining Workers, Victor F. Nunfam, Ebenezer Afrifa-Yamoah, Kwadwo Adusei-Asante, Eddie J. Van Etten, Kwasi Frimpong, Isaac Adjei-Mensah, Jacques Oosthuizen Jun 2021

Construct Validity And Invariance Assessment Of The Social Impacts Of Occupational Heat Stress Scale (Siohss) Among Ghanaian Mining Workers, Victor F. Nunfam, Ebenezer Afrifa-Yamoah, Kwadwo Adusei-Asante, Eddie J. Van Etten, Kwasi Frimpong, Isaac Adjei-Mensah, Jacques Oosthuizen

Research outputs 2014 to 2021

Heat exposure studies over the last decade have shown little attention in assessing and reporting the psychometric properties of the various scales used to measure impacts of occupational heat stress on workers. A descriptive cross-sectional survey including 320 small- and large-scale mining workers was employed to assess the construct validity of the social impacts of occupational heat stress scale (SIOHSS) in the Western Region of Ghana in 2017. A confirmatory factor analysis (CFA) and invariance analysis were carried out using AMOS version 25 and statistical product and service solutions (SPSS) version 26 to examine the model fit and establish consistency …


The Influence Of Mental Fatigue On Sessional Ratings Of Perceived Exertion In Elite Open And Closed Skill Sports Athletes, Joseph O. C. Coyne, Aaron J. Coutts, Robert U. Newton, G. Gregory Haff Apr 2021

The Influence Of Mental Fatigue On Sessional Ratings Of Perceived Exertion In Elite Open And Closed Skill Sports Athletes, Joseph O. C. Coyne, Aaron J. Coutts, Robert U. Newton, G. Gregory Haff

Research outputs 2014 to 2021

ABSTRACT: Coyne, JOC, Coutts, AJ, Newton, RU, and Haff, GG. The influence of mental fatigue on sessional ratings of perceived exertion in elite open and closed skill sports athletes. J Strength Cond Res 35(4): 963-969, 2021-The main purpose of this investigation was to examine influence of mental fatigue on sessional ratings of perceived exertion (sRPE) over a training week in elite athletes in open skill (OS, i.e., more unpredictable and externally paced sports) and closed skill (CS, i.e., more predictable and internally paced) sports. Visual analogue scales for mental fatigue, sRPE (CR-10 scale), and training duration were collected from an …


Fitness Testing Parameters For Alpine Ski Racing, James J. Pritchard Apr 2021

Fitness Testing Parameters For Alpine Ski Racing, James J. Pritchard

Research outputs 2014 to 2021

Alpine ski racing requires high levels of isometric, eccentric, and concentric muscle actions through wide ranges of hip, knee, and ankle mobility. The course duration of ∼ 40 seconds for slalom racing to upward of 2.5 minutes for downhill racing necessitates high levels of anaerobic endurance, aerobic power, and force production to be successful. In addition, due to the highly technical skill aspect of ski racing, neuromuscular coordination is of utmost importance. This review identifies the most effective performance testing methods for alpine ski racing, as well as highlighting their relevance to the physiological parameters of the sport.


Blood Transcriptome Profiling As Potential Biomarkers Of Suboptimal Health Status: Potential Utility Of Novel Biomarkers For Predictive, Preventive, And Personalized Medicine Strategy, Hao Wang, Qiuyue Tian, Jie Zhang, Hongqi Liu, Jinxia Zhang, Weijie Cao, Xiaoyu Zhang, Xingang Li, Lijuan Wu, Manshu Song, Yuanyuan Kong, Wei Wang, Youxin Wang Apr 2021

Blood Transcriptome Profiling As Potential Biomarkers Of Suboptimal Health Status: Potential Utility Of Novel Biomarkers For Predictive, Preventive, And Personalized Medicine Strategy, Hao Wang, Qiuyue Tian, Jie Zhang, Hongqi Liu, Jinxia Zhang, Weijie Cao, Xiaoyu Zhang, Xingang Li, Lijuan Wu, Manshu Song, Yuanyuan Kong, Wei Wang, Youxin Wang

Research outputs 2014 to 2021

The early identification of Suboptimal Health Status (SHS) creates a window opportunity for the predictive, preventive, and personalized medicine (PPPM) in chronic diseases. Previous studies have observed the alterations in several mRNA levels in SHS individuals. As a promising “omics” technology offering comprehension of genome structure and function at RNA level, transcriptome profiling can provide innovative molecular biomarkers for the predictive identification and targeted prevention of SHS. To explore the potential biomarkers, biological functions, and signalling pathways involved in SHS, an RNA sequencing (RNA-Seq)–based transcriptome analysis was firstly conducted on buffy coat samples collected from 30 participants with SHS and …


Relationships Between Internal Training Load In A Taper With Elite Weightlifting Performance Calculated Using Different Moving Average Methods, Joseph O. C. Coyne, Robert U. Newton, G. Gregory Haff Mar 2021

Relationships Between Internal Training Load In A Taper With Elite Weightlifting Performance Calculated Using Different Moving Average Methods, Joseph O. C. Coyne, Robert U. Newton, G. Gregory Haff

Research outputs 2014 to 2021

Purpose:

A simple and 2 different exponentially weighted moving average methods were used to investigate the relationships between internal training load and elite weightlifting performance.

Methods:

Training impulse data (sessional ratings of perceived exertion × training duration) were collected from 21 elite weightlifters (age = 26.0 [3.2] y, height = 162.2 [11.3] cm, body mass = 72.2 [23.8] kg, previous 12-mo personal best total 96.3% [2.7%] of world record total) during the 8 weeks prior to the 2016 Olympic Games qualifying competition. The amount of training modified or cancelled due to injury/illness was also collected. The training stress balance (TSB) …


Association Of Habitual Intake Of Fruits And Vegetables With Depressive Symptoms: The Ausdiab Study, Simone Radavelli-Bagatini, Reindolf Anokye, Nicola P. Bondonno, Marc Sim, Catherine P. Bondonno, Mandy J. Stanley, Craig Harms, Richard Woodman, Dianna J. Magliano, Jonathan E. Shaw, Robin M. Daly, Jonathan M. Hodgson, Joshua R. Lewis, Lauren C. Blekkenhorst Mar 2021

Association Of Habitual Intake Of Fruits And Vegetables With Depressive Symptoms: The Ausdiab Study, Simone Radavelli-Bagatini, Reindolf Anokye, Nicola P. Bondonno, Marc Sim, Catherine P. Bondonno, Mandy J. Stanley, Craig Harms, Richard Woodman, Dianna J. Magliano, Jonathan E. Shaw, Robin M. Daly, Jonathan M. Hodgson, Joshua R. Lewis, Lauren C. Blekkenhorst

Research outputs 2014 to 2021

Purpose:

To investigate the relationship of habitual FV intake, different types of FV, and vegetable diversity with depressive symptoms.

Methods:

Australian men and women (n = 4105) aged > 25 years from the Australian Diabetes, Obesity and Lifestyle Study were included. Dietary intake was assessed using a Food Frequency Questionnaire at baseline, 5 and 12 years. Depressive symptoms were assessed using the validated 10-item Centre for Epidemiology Studies Short Depression Scale at 12 years. Multiple logistic regression models were used to investigate the association between the exposures of interest and depressive symptoms using odds ratios (OR) and 95% confidence intervals (CI) …


A Quantitative Exploration Of The Relationships Between Regular Yoga Practice, Microdosing Psychedelics, Wellbeing And Personality Variables, Stephen Bright, Eyal Gringart, Emily Blatchford, Samantha Bettinson Mar 2021

A Quantitative Exploration Of The Relationships Between Regular Yoga Practice, Microdosing Psychedelics, Wellbeing And Personality Variables, Stephen Bright, Eyal Gringart, Emily Blatchford, Samantha Bettinson

Research outputs 2014 to 2021

Objective:

The current study aimed to explore whether the subjective effects of microdosing psychedelics are comparable to those of yoga in relation to psychological wellbeing, depression, anxiety and stress. It also explored the relationship between yoga, microdosing and personality.

Method:

The sample comprised 339 participants, yoga (n = 131), microdose (n = 69), microdose and yoga (n = 54) and control (n = 85). All completed measures of personality (M5-50 and Tellegen Absorption Scale), mood (Depression, Anxiety and Stress Scale-21) and wellbeing (Ryff Scales of Psychological Wellbeing).

Results:

The yoga and microdosing groups scored significantly higher on psychological wellbeing and …


Relationships Between Different Internal And External Training Load Variables And Elite International Women’S Basketball Performance, Joseph Coyne, Aaron J. Coutts, Robert Newton, Greg Haff Feb 2021

Relationships Between Different Internal And External Training Load Variables And Elite International Women’S Basketball Performance, Joseph Coyne, Aaron J. Coutts, Robert Newton, Greg Haff

Research outputs 2014 to 2021

Purpose:

To investigate the relationships between internal and external training load (TL) metrics with elite international women’s basketball performance.

Methods:

Sessional ratings of perceived exertion, PlayerLoad/minute, and training duration were collected from 13 elite international-level female basketball athletes (age 29.0 [3.7] y, stature 186.0 [9.8] cm, body mass 77.9 [11.6] kg) during the 18 weeks prior to the International Basketball Federation Olympic qualifying event for the 2016 Rio Olympic Games. Training stress balance, differential load, and the training efficiency index were calculated with 3 different smoothing methods. These TL metrics and their change in the last 21 days …


Hyaluronic Acid In Viscous Malignant Mesothelioma Pleural Effusion, Hui Min Cheah, Deirdre Fitzgerald, Amber Louw, Jenette Creaney, Y. C.Gary Lee Jan 2021

Hyaluronic Acid In Viscous Malignant Mesothelioma Pleural Effusion, Hui Min Cheah, Deirdre Fitzgerald, Amber Louw, Jenette Creaney, Y. C.Gary Lee

Research outputs 2014 to 2021

© 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology Malignant pleural effusion (MPE) is common with mesothelioma. We report two cases of extraordinarily viscous MPEs associated with mesothelioma. The viscosity prohibited spontaneous gravity-dependent drainage via indwelling pleural catheters. Our ex vivo experiments found very high hyaluronic acid (HA) content within the fluid. Treatment of the fluid with hyaluronidase, but not with deoxyribonucleases, significantly reduced fluid viscosity. The results provide proof that HA can contribute to high viscosity of pleural fluid in mesothelioma. Research into strategies …


Comparison Of Circulating Tumour Dna And Extracellular Vesicle Dna By Low-Pass Whole-Genome Sequencing Reveals Molecular Drivers Of Disease In A Breast Cancer Patient, Olivia Ruhen, Bob Mirzai, Michael E. Clark, Bella Nguyen, Carlos Salomon, Wendy Erber, Katie Meehan Jan 2021

Comparison Of Circulating Tumour Dna And Extracellular Vesicle Dna By Low-Pass Whole-Genome Sequencing Reveals Molecular Drivers Of Disease In A Breast Cancer Patient, Olivia Ruhen, Bob Mirzai, Michael E. Clark, Bella Nguyen, Carlos Salomon, Wendy Erber, Katie Meehan

Research outputs 2014 to 2021

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. There is increasing recognition of circulating tumour DNA (ctDNA) as a non-invasive alternative to tumour tissue for the molecular characterisation and monitoring of disease. Recent evidence suggests that cancer-associated changes can also be detected in the DNA contained within extracellular vesicles (EVs). As yet, there has been limited investigation into the relationship between EV DNA and ctDNA, and no studies have examined the EV DNA of breast cancer patients. The aim of this study was to use low-pass whole-genome sequencing to identify copy number variants (CNVs) in serial samples of both …


To Dine In Or Not To Dine In: A Comparison Of Food Selection And Preparation Behaviours In Those With And Without Food Security, Lucy M. Butcher, Therese A. O’Sullivan, Maria M. Ryan, Johnny Lo, Julie Nyanjom, Hugh C. Wilkins, Amanda Devine Jan 2021

To Dine In Or Not To Dine In: A Comparison Of Food Selection And Preparation Behaviours In Those With And Without Food Security, Lucy M. Butcher, Therese A. O’Sullivan, Maria M. Ryan, Johnny Lo, Julie Nyanjom, Hugh C. Wilkins, Amanda Devine

Research outputs 2014 to 2021

© 2020 The Authors. Health Promotion Journal of Australia published by John Wiley & Sons Australia, Ltd on behalf of Australian Health Promotion Association Issue addressed: Vulnerable populations are disproportionately affected by food insecurity, resulting in heightened risk of suboptimal dietary intake. Food insecure people appear to implement several coping strategies and dietary compromises to avoid hunger. Less explored in the literature is how these strategies impact consumption of food inside and outside of the home. Methods: An online survey was completed by adults (n = 1292) residing in one of five Australian states. The questionnaire comprised of the six-item …


Involuntary Sustained Firing Of Plantar Flexor Motor Neurones: Effect Of Electrical Stimulation Parameters During Tendon Vibration, Ricardo N. O. Mesquita, Janet L. Taylor, Benjamin Kirk, Anthony J. Blazevich Jan 2021

Involuntary Sustained Firing Of Plantar Flexor Motor Neurones: Effect Of Electrical Stimulation Parameters During Tendon Vibration, Ricardo N. O. Mesquita, Janet L. Taylor, Benjamin Kirk, Anthony J. Blazevich

Research outputs 2014 to 2021

Purpose

Simultaneous application of tendon vibration and neuromuscular electrical stimulation (NMES) induces an involuntary sustained torque. We examined the effect of different NMES parameters (intensity, pattern of stimulation and pulse width) on the magnitude of the evoked involuntary torque.

Methods

Plantar flexor torque was recorded during 33-s Achilles tendon vibration with simultaneous 20-Hz NMES bouts on triceps surae (n = 20; 13 women). Intensity was set to elicit 10, 20 or 30% of maximal voluntary contraction torque (MVC), pulse width was narrow (0.2 ms) or wide (1 ms), and the stimulus pattern varied (5 × 2-s or 10 × …