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Full-Text Articles in Medicine and Health Sciences

The Association Between Environmental Factors And Scarlet Fever Incidence In Beijing Region: Using Gis And Spatial Regression Models, Gehendra Mahara, Chao Wang, Kun Yang, Sipeng Chen, Jin Guo, Qi Gao, Wei Wang, Quanyi Wang, Xiuhua Guo Nov 2016

The Association Between Environmental Factors And Scarlet Fever Incidence In Beijing Region: Using Gis And Spatial Regression Models, Gehendra Mahara, Chao Wang, Kun Yang, Sipeng Chen, Jin Guo, Qi Gao, Wei Wang, Quanyi Wang, Xiuhua Guo

Research outputs 2014 to 2021

Background:

Evidence regarding scarlet fever and its relationship with meteorological, including air pollution factors, is not very available. This study aimed to examine the relationship between ambient air pollutants and meteorological factors with scarlet fever occurrence in Beijing, China.

Methods:

A retrospective ecological study was carried out to distinguish the epidemic characteristics of scarlet fever incidence in Beijing districts from 2013 to 2014. Daily incidence and corresponding air pollutant and meteorological data were used to develop the model. Global Moran’s I statistic and Anselin’s local Moran’s I (LISA) were applied to detect the spatial autocorrelation (spatial dependency) and clusters of …


The Interpretive Approach As A Means Of Understanding The Misunderstood, Doreen Molloy, Joyce Hendricks, Anne Williams Nov 2016

The Interpretive Approach As A Means Of Understanding The Misunderstood, Doreen Molloy, Joyce Hendricks, Anne Williams

Research outputs 2014 to 2021

People’s experiences of health and illness are important areas of health research and practice. The interpretive process, and more significantly the biographical approach (Denzin, 1989), is an approach in which there is a focus on personal epiphanies which shape and reflect the stories people tell of their experiences. Dolby-Stahl (1985) contends stories of personal experience sit within the genre of folklore and that the reading of such stories must take into account the social, cultural, and historical contexts which influence and give meaning to experience.


Single-Leg Squats Can Predict Leg Alignment In Dancers Performing Ballet Movements In "Turnout", Luke Hopper, Nahoko Sato, Andries L. Weidemann Nov 2016

Single-Leg Squats Can Predict Leg Alignment In Dancers Performing Ballet Movements In "Turnout", Luke Hopper, Nahoko Sato, Andries L. Weidemann

Research outputs 2014 to 2021

The physical assessments used in dance injury surveillance programs are often adapted from the sports and exercise domain. Bespoke physical assessments may be required for dance, particularly when ballet movements involve “turning out” or external rotation of the legs beyond that typically used in sports. This study evaluated the ability of the traditional single-leg squat to predict the leg alignment of dancers performing ballet movements with turnout. Three-dimensional kinematic data of dancers performing the single-leg squat and five ballet movements were recorded and analyzed. Reduction of the three-dimensional data into a one-dimensional variable incorporating the ankle, knee, and hip joint …


The Efficacy Of A Group Cognitive Behavioral Therapy For War-Affected Young Migrants Living In Australia: A Cluster Randomized Controlled Trial, Chew S. Ooi, Rosanna M. Rooney, Clare Roberts, Robert T. Kane, Bernadette Wright, Nikos Chatzisarantis Oct 2016

The Efficacy Of A Group Cognitive Behavioral Therapy For War-Affected Young Migrants Living In Australia: A Cluster Randomized Controlled Trial, Chew S. Ooi, Rosanna M. Rooney, Clare Roberts, Robert T. Kane, Bernadette Wright, Nikos Chatzisarantis

Research outputs 2014 to 2021

Background: Preventative and treatment programs for people at risk of developing psychological problems after exposure to war trauma have mushroomed in the last decade. However, there is still much contention about evidence-based and culturally sensitive interventions for children. The aim of this study was to examine the efficacy of the Teaching Recovery Techniques in improving the emotional and behavioral outcomes of war-affected children resettled in Australia.

Methods and Findings: A cluster randomized controlled trial with pre-test, post-test, and 3-month follow-up design was employed. A total of 82 participants (aged 10–17 years) were randomized by school into the 8-week intervention ( …


Photoaging Photography: Mothers' Attitudes Toward Adopting Skin-Protective Measures Pre- And Post-Viewing Photoaged Images Of Their And Their Child's Facial Sun Damage, Matthew Welch, Paul Chang, Myra F. Taylor Oct 2016

Photoaging Photography: Mothers' Attitudes Toward Adopting Skin-Protective Measures Pre- And Post-Viewing Photoaged Images Of Their And Their Child's Facial Sun Damage, Matthew Welch, Paul Chang, Myra F. Taylor

Research outputs 2014 to 2021

One of the major sources for children to gain knowledge of skin-protective measures is from their parents. Therefore, an imperative exists for parents to model and reinforce the sun-safety practices they want their children to adopt. Although Australian mothers have been the recipients of two extensive sun-safety public health campaigns, little is known about their attitudes, behaviors, and application of health promotion knowledge toward their and their child’s ultraviolet (UV) sun exposure. Ten mothers with children aged 4 to 12 years were asked a series of questions about their sun-safety practices, both pre- and post-viewing an UV photoaged photograph of …


Integrating Diet And Exercise Into Care Of Prostate Cancer Patients On Androgen Deprivation Therapy, Mark A. Moyad, Robert Newton, Ulf W. Tunn, Damian Gruca Aug 2016

Integrating Diet And Exercise Into Care Of Prostate Cancer Patients On Androgen Deprivation Therapy, Mark A. Moyad, Robert Newton, Ulf W. Tunn, Damian Gruca

Research outputs 2014 to 2021

Improved diagnosis and treatment regimens have resulted in greater longevity for men with prostate cancer. This has led to an increase in both androgen deprivation therapy (ADT) use and duration of exposure, and therefore to its associated adverse effects, such as sexual dysfunction, osteoporosis, reduced muscle mass, increased fat mass, and increased incidence of cardiovascular disease and type 2 diabetes. Given that the adverse effects of ADT are systemic, often debilitating, and difficult to treat, efforts continue in the development of new strategies for long-term management of prostate cancer. The PubMed database was searched to select trials, reviews, and meta-analyses …


Local Muscle Metabolic Demand Induced By Neuromuscular Electrical Stimulation And Voluntary Contractions At Different Force Levels: A Nirs Study, Makii Muthalib, Graham Kerr, Kazunori Nosaka, Stephane Perrey Jun 2016

Local Muscle Metabolic Demand Induced By Neuromuscular Electrical Stimulation And Voluntary Contractions At Different Force Levels: A Nirs Study, Makii Muthalib, Graham Kerr, Kazunori Nosaka, Stephane Perrey

Research outputs 2014 to 2021

Functional Muscle metabolic demand during contractions evoked by neuromuscular electrical stimulation (NMES) has been consistently documented to be greater than voluntary contractions (VOL) at the same force level (10-50% maximal voluntary contraction-MVC). However, we have shown using a near-infrared spectroscopy (NIRS) technique that local muscle metabolic demand is similar between NMES and VOL performed at MVC levels, thus controversy exists. This study therefore compared biceps brachii muscle metabolic demand (tissue oxygenation index-TOI and total hemoglobin volume-tHb) during a 10s isometric contraction of the elbow flexors between NMES (stimulation frequency of 30Hz and current level to evoke 30% MVC) and VOL …


A Phenotypically Silent Vanb2 Operon Carried On A Tn1549-Like Element In Clostridium Difficile, Daniel R. Knight, Grace O. Androga, Susan A. Ballard, Benjamin P. Howden, Thomas Riley Jun 2016

A Phenotypically Silent Vanb2 Operon Carried On A Tn1549-Like Element In Clostridium Difficile, Daniel R. Knight, Grace O. Androga, Susan A. Ballard, Benjamin P. Howden, Thomas Riley

Research outputs 2014 to 2021

In the last decade, Clostridium difficile infection (CDI) has reached an epidemic state with increasing incidence and severity in both health care and community settings. Vancomycin is an important first-line therapy for CDI, and the emergence of resistance would have significant clinical consequences. In this study, we describe for the first time a vanB2 vancomycin resistance operon in C. difficile, isolated from an Australian veal calf at slaughter. The operon was carried on an ~ 42-kb element showing significant homology and synteny to Tn1549, a conjugative transposon linked with the emergence and global dissemination of vancomycin-resistant enterococci …


Real-Time Netnography: Rejecting The Passive Shift, Leesa Costello, Marie-Louise Mcdermott Apr 2016

Real-Time Netnography: Rejecting The Passive Shift, Leesa Costello, Marie-Louise Mcdermott

Research outputs 2014 to 2021

Although netnography emerged in the 1990s, it is a term unfamiliar to many ethnographers and is still touted as a new methodology. Once explained, ethnographers often understand it in terms of online ethnography. While this is helpful, netnography, however, offers a set of steps and analytic approaches that can be applied across a spectrum of involvement online. Its focus is on gaining entree to an online community, distinguishing between participant observation and nonparticipant observation.


The Role Of Clinical Proteomics, Lipidomics, And Genomics In The Diagnosis Of Alzheimer's Disease, Ian James Martins Mar 2016

The Role Of Clinical Proteomics, Lipidomics, And Genomics In The Diagnosis Of Alzheimer's Disease, Ian James Martins

Research outputs 2014 to 2021

The early diagnosis of Alzheimer’s disease (AD) has become important to the reversal and treatment of neurodegeneration, which may be relevant to premature brain aging that is associated with chronic disease progression. Clinical proteomics allows the detection of various proteins in fluids such as the urine, plasma, and cerebrospinal fluid for the diagnosis of AD. Interest in lipidomics has accelerated with plasma testing for various lipid biomarkers that may with clinical proteomics provide a more reproducible diagnosis for early brain aging that is connected to other chronic diseases. The combination of proteomics with lipidomics may decrease the biological variability between …


Medical Help-Seeking For Sexual Concerns In Prostate Cancer Survivors, Melissa K. Hyde, Leah Zajdlewicz, Addie C. Wootten, Christian J. Nelson, Anthony Lowe, Jeff Dunn, Suzanne K. Chambers Mar 2016

Medical Help-Seeking For Sexual Concerns In Prostate Cancer Survivors, Melissa K. Hyde, Leah Zajdlewicz, Addie C. Wootten, Christian J. Nelson, Anthony Lowe, Jeff Dunn, Suzanne K. Chambers

Research outputs 2014 to 2021

Introduction: Although sexual dysfunction is common after prostate cancer, men's decisions to seek help for sexual concerns are not well understood.

Aim: Describe predictors of actual prior help-seeking and intended future medical help-seeking for sexual dysfunction in prostate cancer survivors.

Methods: A cross-sectional survey of 510 prostate cancer survivors assessed masculine beliefs, attitudes, support/approval from partner/peer networks (subjective norm), and perceived control as predictors of medical help-seeking for sexual concerns. A theory of planned behavior (TPB) perspective was used to examine actual prior and planned future behavior and contributing factors. Statistical analyses included multiple and logistic regressions.

Main Outcome Measures: …


Setting Research Priorities To Improve Global Newborn Health And Prevent Stillbirths By 2025, Sachiyo Yoshida, Jose Martines, Joy E. Lawn, Stephen Wall, Joao Paulo Souza, Igor Rudan, Simon Cousens, Peter Aaby, Ishag Adam, Ramesh Kant Adhikari, Namasivayam Ambalavanan, Shams El Arifeen, Dhana Raj Aryal, Sk Asiruddin, Abdullah Baqui, Aluisio J.D. Barros, Christine S. Benn, Vineet Bhandari, Shinjini Bhatnagar, Sohinee Bhattacharya, Zulfiqar A. Bhutta, Robert E. Black, Hannah Blencowe, Carl Bose, Justin Brown, Christoph Buehrer, Wally Carlo, Jose Guilherme Cecatti, Po-Yin Cheung, Robert Clark, Tim Colbourn, Agustin Conde-Agudelo, Erica Corbett, Andrew E. Czeizel, Abhik Das, Louise Tina Day, Carolyn Deal, Ashok Deorari, Ugur Dilmen, Mike English, Cyril Engmann, Fabian Esamai, Caroline Fall, Donna M. Ferriero, Peter Gisore, Tabish Hazir, Rosemary D. Higgins, Caroline S.E. Homer, Dewan E. Hoque, Lorentz Irgens, Mohammad T. Islam, Joseph De Graft-Johnson, Martias Alice Joshua, William Keenan, Soofia Khatoon, Helle Kieler, Michael S. Kramer, Eve M. Lackritz, Tina Lavender, Laurensia Lawintono, Richard Luhanga, David Marsh, Douglas Mcmillan, Patrick J. Mcnamara, Ben Willem J. Mol, Elizabeth Molyneux, Gelasius K. Mukasa, Miriam Mutabazi, Luis Carlos Nacul, Margaret Nakakeeto, Indira Narayanan, Bolajoko Olusanya, David Osrin, Vinod Paul, Christian Poets, Uma M. Reddy, Mathuram Santosham, Rubayet Sayed, Natalia E. Schlabritz-Loutsevitch, Nalini Singhal, Mary Alice Smith, Peter G. Smith, Sajid Soofi, Catherine Y. Spong, Shahin Sultana, Antoinette Tshefu, Frank Van Bel, Lauren Vestewig Gray, Peter Waiswa, Wei Wang, Sarah L.A. Williams, Linda Wright, Anita Zaidi, Yanfeng Zhang, Nanbert Zhong, Isabel Zuniga, Rajiv Bahl Jan 2016

Setting Research Priorities To Improve Global Newborn Health And Prevent Stillbirths By 2025, Sachiyo Yoshida, Jose Martines, Joy E. Lawn, Stephen Wall, Joao Paulo Souza, Igor Rudan, Simon Cousens, Peter Aaby, Ishag Adam, Ramesh Kant Adhikari, Namasivayam Ambalavanan, Shams El Arifeen, Dhana Raj Aryal, Sk Asiruddin, Abdullah Baqui, Aluisio J.D. Barros, Christine S. Benn, Vineet Bhandari, Shinjini Bhatnagar, Sohinee Bhattacharya, Zulfiqar A. Bhutta, Robert E. Black, Hannah Blencowe, Carl Bose, Justin Brown, Christoph Buehrer, Wally Carlo, Jose Guilherme Cecatti, Po-Yin Cheung, Robert Clark, Tim Colbourn, Agustin Conde-Agudelo, Erica Corbett, Andrew E. Czeizel, Abhik Das, Louise Tina Day, Carolyn Deal, Ashok Deorari, Ugur Dilmen, Mike English, Cyril Engmann, Fabian Esamai, Caroline Fall, Donna M. Ferriero, Peter Gisore, Tabish Hazir, Rosemary D. Higgins, Caroline S.E. Homer, Dewan E. Hoque, Lorentz Irgens, Mohammad T. Islam, Joseph De Graft-Johnson, Martias Alice Joshua, William Keenan, Soofia Khatoon, Helle Kieler, Michael S. Kramer, Eve M. Lackritz, Tina Lavender, Laurensia Lawintono, Richard Luhanga, David Marsh, Douglas Mcmillan, Patrick J. Mcnamara, Ben Willem J. Mol, Elizabeth Molyneux, Gelasius K. Mukasa, Miriam Mutabazi, Luis Carlos Nacul, Margaret Nakakeeto, Indira Narayanan, Bolajoko Olusanya, David Osrin, Vinod Paul, Christian Poets, Uma M. Reddy, Mathuram Santosham, Rubayet Sayed, Natalia E. Schlabritz-Loutsevitch, Nalini Singhal, Mary Alice Smith, Peter G. Smith, Sajid Soofi, Catherine Y. Spong, Shahin Sultana, Antoinette Tshefu, Frank Van Bel, Lauren Vestewig Gray, Peter Waiswa, Wei Wang, Sarah L.A. Williams, Linda Wright, Anita Zaidi, Yanfeng Zhang, Nanbert Zhong, Isabel Zuniga, Rajiv Bahl

Research outputs 2014 to 2021

Background

In 2013, an estimated 2.8 million newborns died and 2.7 million were stillborn. A much greater number suffer from long term impairment associated with preterm birth, intrauterine growth restriction, congenital anomalies, and perinatal or infectious causes. With the approaching deadline for the achievement of the Millennium Development Goals (MDGs) in 2015, there was a need to set the new research priorities on newborns and stillbirth with a focus not only on survival but also on health, growth and development. We therefore carried out a systematic exercise to set newborn health research priorities for 2013–2025.

Methods

We used adapted Child …


The Effects Of Latrepirdine On Amyloid-Β Aggregation And Toxicity, Tenielle Porter, Prashant Bharadwaj, David Groth, Adrian Paxman, Simon Laws, Ralph Martins, Guiseppe Verdile Jan 2016

The Effects Of Latrepirdine On Amyloid-Β Aggregation And Toxicity, Tenielle Porter, Prashant Bharadwaj, David Groth, Adrian Paxman, Simon Laws, Ralph Martins, Guiseppe Verdile

Research outputs 2014 to 2021

Latrepirdine (DimebonTM) has been demonstrated to be a neuroprotective and cognition improving agent in neurodegenerative diseases that feature protein aggregation and deposition, such as Alzheimer's disease (AD). The accumulation of amyloid-β (Aβ) protein aggregates is a key event in the neurodegenerative process in AD. This study explores if latrepirdine modulation of protein aggregation contributes to its neuroprotective mechanism of action. Assessment of neuronal cell death showed that there was a significant reduction in lactate dehydrogenase release at an equimolar ratio of Aβ:latrepirdine and with lower concentrations of latrepirdine. The ability of latrepirdine to alter the formation of Aβ42 aggregates was …


Goal Fluency, Pessimism And Disengagement In Depression, Joanne M. Dickson, Nicholas Moberly, Christian O'Dea, Matt Field Jan 2016

Goal Fluency, Pessimism And Disengagement In Depression, Joanne M. Dickson, Nicholas Moberly, Christian O'Dea, Matt Field

Research outputs 2014 to 2021

Despite the development of prominent theoretical models of goal motivation and its importance in daily life, research has rarely examined goal dysregulation processes in clinical depression. Here we aimed to investigate problematic aspects of goal regulation in clinically depressed adults, relative to controls. Depressed participants (n = 42) were recruited from two Improving Access to Psychological Therapy clinics in north-west England. Control participants (n = 51) were recruited from the same region. Participants generated personal approach goals (e.g., improve my marathon time) and avoidance goals (e.g., avoid getting upset over little things) and completed self-report measures of goal attainment likelihood …


Motor Subtype As A Predictor Of Future Working Memory Performance In Idiopathic Parkinson's Disease, Andrew R. Johnson, Romola S. Bucks, Robert T. Kane, Meghan G. Thomas, Natalie Gasson, Andrea M. Loftus Jan 2016

Motor Subtype As A Predictor Of Future Working Memory Performance In Idiopathic Parkinson's Disease, Andrew R. Johnson, Romola S. Bucks, Robert T. Kane, Meghan G. Thomas, Natalie Gasson, Andrea M. Loftus

Research outputs 2014 to 2021

Parkinson’s disease is a progressive neurodegenerative disorder associated with reduced spatial and verbal working memory ability. There are two established motor subtypes of PD, tremor dominant (TD) and postural instability and gait difficulty (PIGD). This study used structural equation modelling to explore the longitudinal relationship between the two subtypes and working memory assessed at a 2-year follow-up. The study comprised 84 males and 30 females (N = 114), aged between 39 and 85 (M = 64.82, SD = 9.23) with confirmed PD. There was no significant relationship between motor subtype at Time 1 and working memory at Time 2. Postural …


Impaired Energy Metabolism: Involvement In Neurodegenerative Processes And Cns Ageing, Veer B. Gupta, Vivek K. Gupta Jan 2016

Impaired Energy Metabolism: Involvement In Neurodegenerative Processes And Cns Ageing, Veer B. Gupta, Vivek K. Gupta

Research outputs 2014 to 2021

World is experiencing a consistent and steady increase in the ageing population with even higher proportional differences in the developed countries. Increase in ageing populations is directly correlated with the increased prevalence of age-related degenerative diseases of the central nervous system (CNS) such as Alzheimer’s disease and various other forms of dementias, stroke, Parkinson’s disease, retinal degenerative disorders, Huntington’s’ disease, multiple sclerosis, psychiatric and behavioural disorders amongst others.


Engaging Australian Aboriginal Narratives To Challenge Attitudes And Create Empathy In Health Care: A Methodological Perspective, Toni D. Wain, Moira Sim, Dawn Bessarab, Donna Mak, Colleen Hayward, Cobie Rudd Jan 2016

Engaging Australian Aboriginal Narratives To Challenge Attitudes And Create Empathy In Health Care: A Methodological Perspective, Toni D. Wain, Moira Sim, Dawn Bessarab, Donna Mak, Colleen Hayward, Cobie Rudd

Research outputs 2014 to 2021

Background:

Unconscious bias and negative attitudes towards minority groups have detrimental effects on the way health care is, or is not, provided to these groups. Recognition of racist attitudes and behaviours as well as understanding clients' experiences of health and health care are pivotal to developing better health care strategies to positively impact on the quality and safety of care provided to Indigenous people. Indigenous research demands inclusive research processes and the use of culturally appropriate methodologies. This paper presents a methodological account of collecting narratives which accurately and respectfully reflect Aboriginal Australians' experiences with health care in Western Australia. …


Effects Of Exercise Interventions And Physical Activity Behavior On Cancer Related Cognitive Impairments: A Systematic Review, Philipp Zimmer, Freerk Baumann, Max Oberste, Peter Wright, Alexander Garthe, Alexander Schenk, Thomas Elter, Daniel A. Galvao, Wilhelm Bloch, Sven Hübner, Florian Wolf Jan 2016

Effects Of Exercise Interventions And Physical Activity Behavior On Cancer Related Cognitive Impairments: A Systematic Review, Philipp Zimmer, Freerk Baumann, Max Oberste, Peter Wright, Alexander Garthe, Alexander Schenk, Thomas Elter, Daniel A. Galvao, Wilhelm Bloch, Sven Hübner, Florian Wolf

Research outputs 2014 to 2021

This systematic review analyzes current data on effects of exercise interventions and physical activity behavior on objective and subjective cancer related cognitive impairments (CRCI). Out of the 19 studies which met all inclusion criteria, five RCTs investigated rodents, whereas the other 14 trials explored humans and these included six RCTs, one controlled trial, two prospective noncontrolled trials, one case series, one observational study, and three cross-sectional studies. The results from animal models revealed positive effects of exercise during and after chemotherapy or radiation on structural alterations of the central nervous system, physiological as well as neuropsychological outcomes. The overall study …


Neuroendocrine And Neurotrophic Signaling In Huntington's Disease: Implications For Pathogenic Mechanisms And Treatment Strategies, Danielle Bartlett, Travis M. Cruickshank, Anthony J. Hannan, Peter R. Eastwood, Alpár S. Lázár, Mel R. Ziman Dr Jan 2016

Neuroendocrine And Neurotrophic Signaling In Huntington's Disease: Implications For Pathogenic Mechanisms And Treatment Strategies, Danielle Bartlett, Travis M. Cruickshank, Anthony J. Hannan, Peter R. Eastwood, Alpár S. Lázár, Mel R. Ziman Dr

Research outputs 2014 to 2021

Huntington's disease (HD) is a fatal neurodegenerative disease caused by an extended polyglutamine tract in the huntingtin protein. Circadian, sleep and hypothalamic-pituitary-adrenal (HPA) axis disturbances are observed in HD as early as 15 years before clinical disease onset. Disturbances in these key processes result in increased cortisol and altered melatonin release which may negatively impact on brain-derived neurotrophic factor (BDNF) expression and contribute to documented neuropathological and clinical disease features. This review describes the normal interactions between neurotrophic factors, the HPA-axis and circadian rhythm, as indicated by levels of BDNF, cortisol and melatonin, and the alterations in these intricately balanced …


Predictors Of Sun Protection Behaviours And Sunburn Among Australian Adolescents, Simone Pettigrew, Michelle Jongenelis, Mark Strickland, Carolyn Minto, Terry Slevin, Geoffrey Jalleh, Chad Lin Jan 2016

Predictors Of Sun Protection Behaviours And Sunburn Among Australian Adolescents, Simone Pettigrew, Michelle Jongenelis, Mark Strickland, Carolyn Minto, Terry Slevin, Geoffrey Jalleh, Chad Lin

Research outputs 2014 to 2021

Background

Excessive sun exposure and sunburn increase individuals’ risk of skin cancer. It is especially important to prevent sunburn in childhood due to the higher relative risk of skin cancer across the life span compared to risk associated with sunburn episodes experienced later in life. This study examined demographic and attitudinal factors associated with engagement in a range of sun protection behaviours (wearing a hat, wearing protective clothing, staying in the shade, and staying indoors during the middle of the day) and the frequency of sunburn among Western Australian adolescents to provide insights of relevance for future sun protection campaigns. …


The Impact Of Adding Assistants In Nursing To Acute Care Hospital Ward Nurse Staffing On Adverse Patient Outcomes: An Analysis Of Administrative Health Data, Diane E. Twigg, Helen Myers, Christine M. Duffield, Judith Dianne Pugh, Lucy Gelder Jan 2016

The Impact Of Adding Assistants In Nursing To Acute Care Hospital Ward Nurse Staffing On Adverse Patient Outcomes: An Analysis Of Administrative Health Data, Diane E. Twigg, Helen Myers, Christine M. Duffield, Judith Dianne Pugh, Lucy Gelder

Research outputs 2014 to 2021

Objectives:

The aim of this study was to assess the impact of adding assistants in nursing to acute care hospital ward nurse staffing on adverse patient outcomes using administrative health data.

Design:

Logistic regression modelling was used with linked administrative health data to examine the association between seven adverse patient outcomes and use of assistants in nursing utilising a pre-test/ post-test design. Outcomes included were in-hospital 30-day mortality, failure to rescue, urinary tract infection, pressure injury, pneumonia, sepsis and falls with injury.

Setting:

Eleven acute care metropolitan hospitals in Western Australia. Sample: Patients were retained in the dataset if they …


Breastfeeding In Nigeria: A Systematic Review, Emmanuel O. Adewuyi, Kazeem Adefemi Jan 2016

Breastfeeding In Nigeria: A Systematic Review, Emmanuel O. Adewuyi, Kazeem Adefemi

Research outputs 2014 to 2021

Breastfeeding confers numerous benefits on babies and mothers. Early initiation, ‘exclusive breastfeeding’ and breastfeeding for at least two years post-delivery are the recommended practices. This study aims to examine the trends of breastfeeding practice in Nigeria by reviewing available published studies. The online databases of PubMed, Science Direct and the Web of Knowledge were searched using relevant terms. Studies identified were screened for eligibility and those that met the inclusion criteria were included in this review. Graphs and regression equations were generated using Microsoft Excel® to illustrate the duration of and trends in, breastfeeding practices in Nigeria. This review adopts …


Climate Change And Malaria Control: The Importance Of Mitigation And A Call To Action, Emmanuel O. Adewuyi, Kazeem Adefemi Jan 2016

Climate Change And Malaria Control: The Importance Of Mitigation And A Call To Action, Emmanuel O. Adewuyi, Kazeem Adefemi

Research outputs 2014 to 2021

Malaria has remained an important target for global disease control efforts for decades. The streams of funds and, consequently, availability of effective interventions for the disease have resulted in considerable reduction in its burden, globally. Despite the relative success of such global efforts, malaria remains a significant threat in over a hundred countries, worldwide, leading to about one million deaths and hundreds of millions of hospital visits, annually. Many researchers and health commentators have argued that global warming, a consequence of climate change, could be linked – directly or indirectly – to the persistence as well as the re-emergence of …


A Randomised Control Trial Of Salvage Radiotherapy And Androgen Deprivation Therapy Following Prostatectomy: Commentary On Five Year Follow-Up Findings, Scott Williams, John W. Yaxley, Geoffrey D. Coughlin, Robert A. Gardiner Jan 2016

A Randomised Control Trial Of Salvage Radiotherapy And Androgen Deprivation Therapy Following Prostatectomy: Commentary On Five Year Follow-Up Findings, Scott Williams, John W. Yaxley, Geoffrey D. Coughlin, Robert A. Gardiner

Research outputs 2014 to 2021

No abstract provided.


Profiling Igg N-Glycans As Potential Biomarker Of Chronological And Biological Ages: A Community-Based Study In A Han Chinese Population, Xinwei Yu, Youix Wang, Jasminka Krištić, Jing Dong, Xi Chu, Siqi Ge, Hao Wang, Honghong Fang, Qing Gao, Di Lui, Zhongya Zhao, Hongli Peng, Maja P. Baković, Lijuan Wu, Manshu Song, Igor Rudan, Harry Campbell, Gordan Lauc, Wei Wang Jan 2016

Profiling Igg N-Glycans As Potential Biomarker Of Chronological And Biological Ages: A Community-Based Study In A Han Chinese Population, Xinwei Yu, Youix Wang, Jasminka Krištić, Jing Dong, Xi Chu, Siqi Ge, Hao Wang, Honghong Fang, Qing Gao, Di Lui, Zhongya Zhao, Hongli Peng, Maja P. Baković, Lijuan Wu, Manshu Song, Igor Rudan, Harry Campbell, Gordan Lauc, Wei Wang

Research outputs 2014 to 2021

As an important post-translation modifying process, glycosylation significantly affects the structure and function of immunoglobulin G (IgG) molecules and is essential in many steps of the inflammatory cascade. Studies have demonstrated the potential of using glycosylation features of IgG as a component of predictive biomarkers for chronological age in several European populations, whereas no study has been reported in Chinese. Herein, we report various patterns of changes in IgG glycosylation associated with age by analyzing IgG glycosylation in 701 community-based Han Chinese (244 males, 457 females; 23-68 years old). Eleven IgG glycans, including FA2B, A2G1, FA2[6]G1, FA2[3]G1, FA2[6]BG1, FA2[3]BG1, A2G2, …


Resilience As Resistance To The New Managerialism: Portraits That Reframe Nursing Through Quotes From The Field, Vicki Cope, Bronwyn Jones, Joyce Hendricks Jan 2016

Resilience As Resistance To The New Managerialism: Portraits That Reframe Nursing Through Quotes From The Field, Vicki Cope, Bronwyn Jones, Joyce Hendricks

Research outputs 2014 to 2021

Aim:

This paper acknowledges the relationship between resilience and the new managerialism of contemporary nursing.

Methods:

Qualitative portraiture methodology.

Discussion:

The new managerialism in hospital settings results in a rapidly increasing turnover of acutely ill or comorbid patients, which directly relates to retention and quality service. In education settings, the management imperative to recruit more students into the profession combined with financial cutbacks leads to similar tensions. In aged care the trend equates care directly with funding, with the same effect. Yet despite this, many registered nurses remain working. Portraiture explored 'why' nurses remain in workplaces often described as awful. …


Nursing Education In China: Meeting The Global Demand For Quality Healthcare, Carol Wang, Lisa Whitehead, Sara J. Bayes Jan 2016

Nursing Education In China: Meeting The Global Demand For Quality Healthcare, Carol Wang, Lisa Whitehead, Sara J. Bayes

Research outputs 2014 to 2021

With a predicted global nursing shortage, ensuring the provision of quality healthcare has become a pressing concern. In China, these concerns include the need to produce nurses trained to a level to support advancing nursing practice and a healthcare system that supports the growth and retention of nurses in China. This paper argues that the standard of nursing education in China plays a crucial role in preparing graduates to meet the health demands of China's growing population and the role that China can play into the future in the global progression of nursing. Collaboration between nursing authorities, educators, and legislators …


Molecular Determinants And Interaction Data Of Cyclic Peptide Inhibitor With The Extracellular Domain Of Trkb Receptor, Nitin Chitranshi, Vivek Gupta, Yogita Dheer, Veer Gupta, Roshana Vander Wall, Stuart Graham Jan 2016

Molecular Determinants And Interaction Data Of Cyclic Peptide Inhibitor With The Extracellular Domain Of Trkb Receptor, Nitin Chitranshi, Vivek Gupta, Yogita Dheer, Veer Gupta, Roshana Vander Wall, Stuart Graham

Research outputs 2014 to 2021

TrkB is a high affinity receptor for the brain derived neurotrophic factor (BDNF) and its phosphorylation stimulates activation of several intracellular signalling pathways linked to cellular growth, differentiation and maintenance. Identification of various activators and inhibitors of the TrkB receptor and greater understanding their binding mechanisms is critical to elucidate the biochemical and pharmacological pathways and analyse various protein crystallization studies. The data presented here is related to the research article entitled "Brain Derived neurotrophic factor is involved in the regulation of glycogen synthase kinase 3β (GSK3β) signalling" [1]. Cyclotraxin B (CTXB) is a disulphide bridge linked cyclic peptide molecule …


Improving Access To Primary Care For Aboriginal Babies In Western Australia: Study Protocol For A Randomized Controlled Trial, Dan Mcaullay, Kimberley Mcauley, Rhonda Marriott, Glenn Pearson, Peter Jacoby, Chantal Ferguson, Elizabeth Geelhoed, Juli Coffin, Charmaine Green, Selina Sibosado, Barbara Henry, Dorota Doherty, Karen Edmond Jan 2016

Improving Access To Primary Care For Aboriginal Babies In Western Australia: Study Protocol For A Randomized Controlled Trial, Dan Mcaullay, Kimberley Mcauley, Rhonda Marriott, Glenn Pearson, Peter Jacoby, Chantal Ferguson, Elizabeth Geelhoed, Juli Coffin, Charmaine Green, Selina Sibosado, Barbara Henry, Dorota Doherty, Karen Edmond

Research outputs 2014 to 2021

Background:

Despite a decade of substantial investments in programs to improve access to primary care for Aboriginal mothers and infants, more than 50 % of Western Australian Aboriginal babies are still not receiving primary and preventative care in the early months of life. Western Australian hospitals now input birth data into the Western Australian electronic clinical management system within 48 hours of birth. However, difficulties have arisen in ensuring that the appropriate primary care providers receive birth notification and clinical information by the time babies are discharged from the hospital. No consistent process exists to ensure that choices about primary …


Comparing Biological Markers Of Alzheimer's Disease Across Blood Fraction And Platforms: Comparing Apples To Oranges, Sid E. O'Bryant, Simone Lista, Robert A. Rissman, Melissa Edwards, Fan Zhang, James Hall, Herik Zetterberg, Simon Lovestone, Veer Bular Gupta, Neill Graff-Radford, Ralph N. Martins, Andreas Jeromin, Stephen Waring, Esther Oh, Mitchel Kling, Laura D. Baker, Harald Hampel Jan 2016

Comparing Biological Markers Of Alzheimer's Disease Across Blood Fraction And Platforms: Comparing Apples To Oranges, Sid E. O'Bryant, Simone Lista, Robert A. Rissman, Melissa Edwards, Fan Zhang, James Hall, Herik Zetterberg, Simon Lovestone, Veer Bular Gupta, Neill Graff-Radford, Ralph N. Martins, Andreas Jeromin, Stephen Waring, Esther Oh, Mitchel Kling, Laura D. Baker, Harald Hampel

Research outputs 2014 to 2021

Introduction:

This study investigated the comparability of potential Alzheimer's disease (AD) biomarkers across blood fractions and assay platforms.

Methods:

Nonfasting serum and plasma samples from 300 participants (150 AD patients and 150 controls) were analyzed. Proteomic markers were obtained via electrochemiluminescence or Luminex technology. Comparisons were conducted via Pearson correlations. The relative importance of proteins within an AD diagnostic profile was examined using random forest importance plots.

Results:

On the Meso Scale Discovery multiplex platform, 10 of the 21 markers shared > 50% of the variance across blood fractions (serum amyloid A R2 = 0.99, interleukin (IL)10 R2 = 0.95, fatty …