Computational Engineering Commons^™

A Computational And Mathematical Approach To The Preclinical Development Of Alpha Emitting Radiopharmaceutical Therapies, Abdulaziz Said

McKelvey School of Engineering Graduate Student Theses & Dissertations

Numerous candidate nuclides have been undergoing rigorous preclinical development in the pursuit of novel targeted therapies. Successful development of these drugs relies on the understanding of physiological impacts at the macro and micro scales, in addition to a scalable process for their production. Here, mathematical and computerized approaches have been developed to guide this preclinical development. In this report, two alpha emitting nuclides Pb-212 and Ra-223 are modeled. Radium-223 dichloride citrate a newly approved ion indicated for treatment of bone metastatic castrate resistant prostate cancer, irradiates lesions through targeted uptake in bone at sites of disease. We have undertaken the …

Development Of A Model For Fire Spread In Low-Gravity Conditions, Kathleen Martinus

The Journal of Purdue Undergraduate Research

No abstract provided.

Graph Neural Networks Powered Scientific Paper Recommendation, Junhao Shen

Computer Science and Engineering Theses and Dissertations

Scientific paper recommendation systems aim to help researchers discover relevant papers amidst the vast and ever-growing body of literature. With the exponential yearly increase in scientific publications, the demand for effective paper recommendation solutions has become both critical and increasingly challenging. In recent years, deep learning techniques have revolutionized recommender systems, and scientific paper recommendations have naturally integrated these advancements. In this dissertation, we address these challenges through three progressive contributions.

First, we enhance traditional content-based methods using Graph Neural Networks (GNNs) by introducing a Graph Convolutional Network-strengthened Topic Modeling (GCN-TM) approach. This method improves upon conventional topic modeling techniques …

An Efficient Computational Frameworks For Design And Analysis Of Metamaterials, Raj Pradip Khawale

All Dissertations

Advancement in additive manufacturing helps in building artificial lattice structures with unique properties that are not available in naturally occurring materials or in continuum structures. Specifically, beam-based lattices are well known for producing lightweight structures with very high strength, auxetic behavior, and energy absorption capabilities. In recent years, numerous research studies have been conducted on generating algorithms and frameworks to obtain unusual properties based on the variation in the cell geometry and material properties. However, the exploration of the full design space is hampered in practice primarily due to restrictions on cell tiling variation. Additionally, the lattices are very intricate, …

Sustainable And User-Driven Scope Development Framework For Engineering Design Services Of Transportation Infrastructure Projects, Ahmad Zaki Ghafari

All Dissertations

Rapid economic growth has led to a significant increase in transportation demands, exerting unprecedented pressure on infrastructure systems in the United States. State transportation agencies play a vital role in maintaining and developing transportation infrastructure networks within their regions. State transportation agencies face immense pressure from federal and state governments, elected officials, and the public to deliver projects efficiently and within budget. State transportation agencies rely on professional consultants for engineering design services. Engineering design services for transportation infrastructure projects are delayed due to incomplete inaccurate scope. For state Department of Transportation (DOTs), a streamlined scope development process is essential …

Peer Collaborative Networks In Undergraduate Computing Classrooms, Noah T. Ravetch

Master's Theses

Peers are an invaluable resource for students at undergraduate universities. Many factors can impact how students form connections, some of which are tied to the students’ identities. While social networks have been studied in the context of universities, little research has been done specifically about peer collaboration and even less in the context of computer science classes. Our research aims to gain an understanding of how peer networks form in computing classes and the effect of being involved in one on students’ academic performances. We collected survey data (n = 139) about students’ peer collaborative behaviors in computer science classes. …

Collision Hazard Prevention And Notification For Construction Worker Safety Using Audio Surveillance, Kehinde Elelu

All Dissertations

The construction industry faces significant safety challenges, with collision hazards ranking as the second highest cause of annual fatalities and injuries in the United States, as reported by the Occupational Safety and Health Administration (OSHA). Current collision detection methods predominantly rely on proximity technologies, which necessitate costly and complex installations on each construction equipment piece. Furthermore, auditory situational awareness declines among workers due to hearing loss and intricate construction noises, which further heightens collision risks. This research introduces an innovative, low-cost, audio-based collision prevention technology aimed at enhancing auditory situational awareness for construction workers exposed to high noise levels. The …

Neural Operator And Physics-Informed Deep Learning Approaches For Inverse Design Of Composites And Manufacturing Processes, Minglei Lu

All Dissertations

In this dissertation, artificial intelligence (AI) models are designed and used to accelerate inverse design of composites and manufacturing processes. The critical bottlenecks in machine learning (ML) including data availability, data quality, model generalization and adaptation, interpretability, physical consistency, and the ’black box’ nature of models for the inverse design are addressed. And the proposed AI models are tested under different engineering scenarios. Firstly, a fast deep neural operator (DNO) structure was developed to significantly reduce training time. This model was tested in the context of additive manufacturing, a transformative industrial technology that allows for the creation of materials with …

Innovations In Additive Manufacturing For Socket Fabrication: An Overview, Linda Ziyadatul Faiza, Wahyu Caesarendra, Wahyu Dwi Lestari

Journal of Mechanical Engineering Science and Technology (JMEST)

Additive Manufacturing (AM) has transformed the prosthetics industry, particularly in socket production, which plays a critical role in the comfort, fit, and functionality of prosthetic limbs. This article examines the latest advancements in AM technologies and their applications in socket fabrication. Key techniques like stereolithography (SLA), selective laser sintering (SLS), and fused deposition modeling (FDM) have facilitated the production of highly personalized, lightweight, and durable prosthetic sockets. These methods not only improve design precision but also allow for the use of biocompatible, flexible materials, enhancing both comfort and functionality. Digital design tools have streamlined the production process, reducing lead times …

Tactical Activities To Improve The Effectiveness Of Concrete Batching Plant Based On Overall Equipment Effectiveness Analysis, Yurida Ekawati, Iddo Christian Sutrisno, Teguh Oktiarso

Journal of Mechanical Engineering Science and Technology (JMEST)

The growth of infrastructure projects has led to an increased demand for ready-mix concrete. A company that produces ready-mix concrete using a batching plant encountered difficulties in fulfilling customer orders due to the high rate of machine downtime. Overall equipment effectiveness (OEE) was employed to examine these issues at the tactical activities, where the root causes of losses that occur in the OEE components of availability, performance, and quality were addressed. The OEE analysis was extended to encompass maintenance effectiveness measures, as the anticipated solution to the problem was not the replacement of the machine, but rather an enhancement of …

Structural Simulation Of Wheelchair Ramp Using Finite Element Method, Bhre Wangsa Lenggana, Agung Nugroho, Ubaidillah Ubaidillah

Journal of Mechanical Engineering Science and Technology (JMEST)

Wheelchairs are essential mobility aids for people with disabilities, but they are often limited to flat surfaces and cannot overcome height differences. Portable ramps are an effective solution to overcome this limitation. This research aims to simulate and analyze the structure of a portable ramp for wheelchairs. Simulations were conducted using finite element method analysis software to assess the portable ramp's von Mises stress, deformation, and safety factor in various loading positions. Finite element method (FEM) analysis software was utilized to evaluate key mechanical properties, including von Mises stress, deformation, and safety factor, under different loading conditions and positions. The …

Analysis Of Biomass Briquette Mixed Bagasse And Sugarcane Peel On The Performance Of Forced Top-Lit Updraft Gasifier Stove, Intan Hardiatama, Aron Enruico, Yuni Hermawan, Muhammad Trifiananto, Skriptyan N.H. Syuhri

Journal of Mechanical Engineering Science and Technology (JMEST)

The population growth in Indonesia from 270 million in 2020 to 279 million in 2024 has increased LPG consumption, potentially leading to future fuel shortages. The top-lit updraft (TLUD) gasifier stove using renewable biomass materials, offers a sustainable alternative. Biomass such as bagasse and sugarcane peel can be optimized into charcoal briquettes with high calorific value and low emissions. The calorific value of briquettes can be further enhanced by blending other high–calorific biomass materials. This experimental research focuses on testing the calorific value of raw bagasse and sugarcane peel before carbonization, as well as briquette mixtures (70:30, 50:50, 30:70) using …

The Effect Of Mixing Time And Rotation Speed On The Consistency Of Dough Viscosity In A Horizontal Mixer, Muhammad Akhlis Rizza, Ekky Yovianto Dharsono, Anggit Murdani, Ratna Monasari, Radhi Nurvian Amrullah, Supa Kusuma Aji, Dian Noorvy Khaerudin

Journal of Mechanical Engineering Science and Technology (JMEST)

Cassava must go through several manufacturing processes before it becomes chips on the market, including the process of stirring the dough. The stirring process is an important stage in various food industries. In the stirring process, the viscosity change in the dough is influenced by various factors, including the stirring process time and speed in stirring. Research on dough viscosity is important because it is directly related to the quality of the final product. The purpose of this study is to provide recommendations to users, both in the context of using horizontal mixers and the process of making similar products. …

Optimization Of The Number Of Cylinder Blades In Coffee Pulper Machine: Finite Element Analysis And Simple Additive Weighting Methods, Mochamad Rifki Syahriza, Dwi Djumhariyanto, Nasrul Ilminnafik, Mahros Darsin, Danang Yudistiro, Hari Arbiantara Basuki, Robertoes Koekoeh Koentjoro Wibowo, Ahmad Syuhri, Sumarji Sumarji

Journal of Mechanical Engineering Science and Technology (JMEST)

The increasing interest in coffee in all circles means that coffee production and quality must always increase due to consumer demands. One way to maintain the quality of coffee beans is by breaking them down using a huller machine. This research aims to improve the optimization of coffee machines by modifying the cylinder blades of huller machines with variations of 3, 4, 5, and 7 cylinder blades in terms of static loading design and quality and production capacity of coffee bean breaking. The experiment was carried out using 400 rpm and breaking 10kg of dry coffee cherries every time the …

Turbine Engine Reliability Analysis Using Reliability Availability Maintainability (Ram), Oyong Novareza, Zefry Darmawan, Nasir Widha Setyanto, Effendi Bin Mohamad

Journal of Mechanical Engineering Science and Technology (JMEST)

Electrical energy is a vital necessity characterized by ever-increasing electricity consumption. The most dominating power plant in Indonesia in supplying electricity is the steam power plant, which is 50%. In its implementation, there is damage that occurs where the highest damage is to the general unit with the highest damage to the turbine unit. Therefore, the author uses the reliability, availability, and maintainability method or RAM. The purpose of this study is to determine the value of RAM on the turbine system at PLN and provide recommendations for improvements to system performance. The results showed that the MTTF and MTTR …

Innovative Approaches For Improving Orc Performance: A Review Of Pure Fluids, Zeotropic Mixtures, And Nanoparticles, Ebenezer Kumi, Vasudevarao Veeredhi, Christopher Enweremad

Journal of Mechanical Engineering Science and Technology (JMEST)

Although the organic Rankine Cycle (ORC) is said to effectively capture low-grade heat, its commercialization has been limited because of working fluid constraints and inefficiencies resulting from operating at low temperatures. This study reviews the working fluids used in organic Rankine cycles and examines how nanoparticles could enhance the efficiency of the ORC, by enhancing the thermophysical properties of the working fluids. Results from this review showed that zeotropic mixtures of pure fluids, provide a viable approach to improving the thermophysical characteristics of organic working fluids and have the potential to achieve thermo-economic performance superior to that of individual pure …

Study On Thermal-Fluid-Solid Coupling Characteristics For Helicopter Intermediate Spiral Bevel Gear Reducer, Dongping Sheng, Jie Yang, Chun Su

Journal of Mechanical Engineering Science and Technology (JMEST)

In the helicopter transmission system, the intermediate reducer is particularly special. It uses bevel gear pairs to change the transmission direction and to transfer the rotational speed effectively. Therefore, an in-depth study of the spiral gear pair is crucial to improve the overall performance of the helicopter rotor system. This study focuses on the study of the thermal-fluid-solid coupling characteristics and one-way steady-state thermal finite element analysis are conducted based on volume of fluid multiphase flow simulation theory to provide strong support for the design and optimization of the helicopter intermediate reducer. Several conclusions could be obtained. Firstly, it could …

Captivating Combustion Traits Of Bio-Oil Droplets Enriched With Bio-Additives From The Areca Shell Waste, Muhammad Alif Raehan, Helen Riupassa, Hendry Y. Nanlohy

Journal of Mechanical Engineering Science and Technology (JMEST)

Fuel derived from crude vegetable oil, such as coconut oil, holds promise as an alternative energy source to mitigate the increasing reliance on fossil fuels driven by population growth and industrial activities. The experiment involved suspending a single droplet of crude coconut oil mixed with activated carbon from areca shell waste and placed at the junction on R-type thermocouple (Pt/Pt-Rh13%). The droplets were ignited using a hot wire and subjected to atmospheric pressure and room temperature. Coconut oil comprises a saturated triglyceride carbon chain compound of approximately 91%, and areca shell waste possesses a porous structure that fosters favorable interactions …

Characterization Of Hydroxyapatite Derived From Scallop Shell Waste Synthesized By Sonochemical Method With Different Temperature Calcination, Diki Dwi Pramono, Poppy Puspitasari, Aminnudin Aminnudin, Jeefferie Abd Razak

Journal of Mechanical Engineering Science and Technology (JMEST)

One common bio-ceramic material used in the biomedical industry is hydroxyapatite. Because of its crystallographic and molecular resemblance to the hard tissues of the human body, hydroxyapatite is thought to form. Scallop shells are one natural source of hydroxyapatite, which is high in calcium. This study examines how the calcination temperature affects the characteristics of hydroxyapatite made from leftover scallop shell. Hydroxyapatite was synthesized via the sonochemical method, with calcination conducted at temperatures of 900°C, 1000°C, and 1100°C. The hydroxyapatite that was prepared was assessed using Xray diffraction (XRD) to determine the phase and crystallite size, Scanning Electron Microscopy (SEM) …

Synthesis And In Vitro Testing Of Mg-6zn-Xhap Biocomposites From Beef Bone As Biodegradable Bone Implant Material, Jojor Lamsihar Manalu, Francisca Tjhay, Theodora Kristoforus, Sovian Aritonang

Journal of Mechanical Engineering Science and Technology (JMEST)

This study aimed to develop biodegradable Mg-6Zn hydroxyapatite (Mg-6Zn HAp) biocomposites for potential use in bone replacement applications. The hydroxyapatite (HAp) powders, sourced from cow bone, were synthesized through an eco-friendly and cost-effective process, leveraging bioresources for material sustainability. The Mg-6Zn and HAp powders were mechanically mixed through ball milling for six hours to ensure homogeneity. The resultant powder mixture was then subjected to isostatic pressing at a high pressure of 570 MPa, forming a dense coin-shaped composite with a 1.5 cm diameter. This coin was consolidated in a capsule furnace at elevated temperatures for one hour to enhance material …