Translational Medical Research Commons^™

Cardiovascular: Outcomes And Innovations Report

Annual Reports

2020 Annual Report

Diagnosis And Management Of Adolescents With Polycystic Ovary Syndrome In Primary Care: A Mixed Method Study To Explore Provider Behaviors And Barriers And Facilitators To Practice

Doctor of Philosophy in Translational Heath Sciences Dissertations

Background: Polycystic Ovary Syndrome (PCOS) is a common endocrine disorder in women of reproductive age, associated with complications of metabolic, reproductive, and psychological health. Adolescence is an optimal time for early identification of PCOS in order to mitigate long-term health risks. Pediatric primary care providers (pedPCPs) are the first-line for early identification and coordination of longterm comprehensive management. Limited information exists to describe how PCOS is addressed in primary care and if adolescent-specific guidelines are applied.

Objectives: Describe practice behaviors of pedPCPs in the diagnosis and management of PCOS, and identify barriers and facilitators to inform future interventions to optimize …

Female Breakfast Skippers Display A Disrupted Cortisol Rhythm And Elevated Blood Pressure, Nancy Keim, Kevin Laugero

Publications from USDA-ARS / UNL Faculty

Chronic stress and over-activity in the hypothalamic–pituitary–adrenal (HPA) axis may link breakfast skipping and poor cardiometabolic health. Missing the first major meal of the day in rodents prolongs elevated circulating corticosterone at a time when it's normally decreasing. To extend these findings to humans, we hypothesized that habitual breakfast skippers would display a similar pattern of circulating cortisol and alterations in meal and stress-induced cortisol reactions. Normal weight to obese women aged 18–45 years old who were strictly defined as either breakfast skippers (n = 30) or breakfast eaters (n = 35) were invited to participate in our study. Normal …

Lurasidone Is Not Associated With Risk Of Qtc Prolongation, Halimah Oral

Clinical Research in Practice: The Journal of Team Hippocrates

A critical appraisal and clinical application of Meltzer HY, Cucchiaro J, Silva R, Ogasa M, Phillips D, Xu J, Kalali AH, Scheizer E, Pikalov A, Loebel A. Lurasidone in the treatment of schizophrenia: a randomized, double-blind, placebo- and olanzapine-controlled study. Am J Psychiatry. 2011 Sep;168(9):957-67. doi: https://doi.org/10.1176/appi.ajp.2011.10060907.

The Effects Of Resistance Training Frequency On Muscle Hypertohy And Strength In Healthy Trained Individuals: Literature Review, Alexander Boivin

Honors in the Major Theses

The purpose of this study is to determine the effects of increased resistance training frequency on strength and hypertrophy in trained individuals. Six Studies were deemed eligible based on the inclusion exclusion criteria. The inclusion criteria for this review were healthy trained individuals. “Trained” refers to over one year of resistance training experience. Exclusion Criteria were study’s that examined either untrained or obese individuals as participants. The evidence indicates a dose-response trend in frequency. Resistance training each muscle group twice a week may be superior compared to once per week. Further more, resistance training each muscle group three times a …

Namru-3 Translations Of Parasite Literature From Russian, French, Japanese, Etc. Into English (1934-1964): T1-T100

United States Naval Medical Research Unit 3: Publications

T8. TRANSLATION FROM RUSSIAN. POSPELOVA-SHTROM, M. V. (1945). Concerning certain groups within the genus Haemaphysalis C. L. Koch, and their taxonomic significance. Med. Parasit., Moscow, 14(1):12-18.

T9. TRANSLATION FROM RUSSIAN. LOTOTSKY, B. V. (1956). On the morphology of Haemaphysalis pavlovskyi Pospelova-Shtrom, 1934 (Parasitiformes, Ixodidae). Zool. Zh., 35(9):1415-1417.

T10. TRANSLATION FROM RUSSIAN. KUCHERUK, V. V., SIDOROVA, G. A. and ZHMAEVA, Z. M. (1955). On the self protection of small rodents against tick (Ixodidae) larvae. Zool. Zh., 34(4):948-950.

T11. TRANSLATION FROM JAPANESE. SUGIMOTO, M. (1937). Notes on ticks in the Formosan Mountain Reservation for aborigines. J. Centr. Soc. Vet. Med. Tokyo, 50:303-340. …

Impact Of Social And Cultural Factors On Teenage Pregnancy, Melissa Jordan, Devi Akella

Journal of Health Disparities Research and Practice

United States has the highest level of teenage pregnancy amongst the industrialized nations. Further, the level of teenage pregnancy is highest amongst the minority population. This research study examines the reasons behind high rates of early childbirth amongst African American teenagers. This study uses Bandura’s (1977) Social Learning Theory to deconstruct the factors, which influence and manipulate the overall behavior of the teenagers and initiates them to choose early motherhood over education and career. To ensure better quality of empirical data, the authors collaborated with the pregnant teenagers and a local non-profit community agency using a phenomenological analysis.

Patient And Renal Allograft Outcomes Of Anticoagulation Therapy In Kidney Transplantation, Goni Katz-Greenberg, Md, Rachel Greene

Phase 1

Introduction: Kidney transplant recipients are often on anticoagulation or antiplatelet therapy, for a variety of indications. These medications are associated with increased risk of bleeding but may reduce risk of thrombosis and possible complications such as allograft loss. The aim of our study is to evaluate the effect of perioperative anticoagulation or antiplatelet therapy on patient and allograft outcomes.

Methods: Data collection was done by retrospective chart review of all patients who underwent a kidney or kidney/pancreas transplantation at Thomas Jefferson University Hospital (TJUH) from 2012-2019. We recorded perioperative anticoagulation and antiplatelet therapy, risk factors for bleeding and thrombosis, …

Rethinking Existing Extension Programming: A Foundation For Healthy Aging?, Kelsey Weitzel, Breanne Baker, Stephen Ball, Kristin Miller, Marta Novaes Oliveira, Nicholas J. Spokely, Sloane A. Montgomery

Journal of Extension

Muscle declines are becoming more prevalent in younger adults, driving the need for accessible exercise programs. The Stay Strong, Stay Healthy (SSSH) Extension program was developed for adults 60 years old or older, but for this study, we enrolled 135 participants aged less than 60 years old in rural and urban counties to assess if it could improve their muscle performance. We analyzed data with time and group comparisons using paired t-tests and 2 × 2 repeated measures ANOVAs. Younger adults significantly improved muscle performance after SSSH, and the results were similar between rural and urban counties. This study …

Research Annual Report Fy2014

Research Annual Reports

Annual report of the research at Children's Mercy Hospital in Kansas City MO, a pediatric medical center.