Clostridium Septicum Bacteremia As The Presenting Sign Of Colon Cancer,
2023
HCA Healthcare
Clostridium Septicum Bacteremia As The Presenting Sign Of Colon Cancer, Andrew Abraham, Sripal Padam
North Florida Division GME Research Day 2023
No abstract provided.
Aggressive Digital Papillary Adenocarcinoma,
2023
HCA Healthcare
Aggressive Digital Papillary Adenocarcinoma, Jessica A. Thomas, Alexandra E. Thomson, Savannah Grunhard, George Negrea
South Atlantic Division GME Research Day 2023
No abstract provided.
Paraneoplastic Leukemoid Reaction In Uterus Carcinosarcoma,
2023
HCA Healthcare
Paraneoplastic Leukemoid Reaction In Uterus Carcinosarcoma, Xiaolan Tang, Ashali Jain, Uma Iyer, Jennifer Reppucci
North Florida Division GME Research Day 2023
No abstract provided.
Hairy Cell Leukemia Presenting As Group B Streptococcus Cellulitis And Abscesses,
2023
HCA Healthcare
Hairy Cell Leukemia Presenting As Group B Streptococcus Cellulitis And Abscesses, Hannah Berrett, Mattias D'Anna, Ajay Iyer, Zachary Hancock, Meg Laures, Muzaffar Iqbal
Continental, MidAmerica, & Mountain Divisions GME Research Day 2023
No abstract provided.
Atypical Lymphoma And Monospot Testing: Malignant Deception,
2023
HCA Healthcare
Atypical Lymphoma And Monospot Testing: Malignant Deception, Jacob Keeling, Kavanya Feustel, Changlee Pang, Kevin Ky, Jennifer Griffith, Alexander Enurah
Continental, MidAmerica, & Mountain Divisions GME Research Day 2023
No abstract provided.
Hyperbilirubinemia Due To Klatskin Tumor,
2023
HCA Healthcare
Hyperbilirubinemia Due To Klatskin Tumor, Srijisnu De, Ammar Mahmood, Akash Hazari, Blane Alost, Aasia Khan
Central & West Texas GME Research Day 2023
No abstract provided.
Under The Skin: Unidentified Subcutaneous Nodules,
2023
HCA Healthcare
Under The Skin: Unidentified Subcutaneous Nodules, Jacob Trimble, Sarah Puim
South Atlantic Division GME Research Day 2023
No abstract provided.
Metaplastic Breast Cancer With Melanocytic Features: Rethinking Our Coventional Understanding Of Breast Tumorigenesis,
2023
HCA Healthcare
Metaplastic Breast Cancer With Melanocytic Features: Rethinking Our Coventional Understanding Of Breast Tumorigenesis, Simerun Singh, Ajay Iyer, Nisreen Haideri, Omar Hameed
Continental, MidAmerica, & Mountain Divisions GME Research Day 2023
No abstract provided.
A Unique Case Of Her2-Positive Adenocarcinoma Of The Small Bowel,
2023
HCA Healthcare
A Unique Case Of Her2-Positive Adenocarcinoma Of The Small Bowel, Alexandria Dennison, Ajay Iyer, Joseph Stilwill
Continental, MidAmerica, & Mountain Divisions GME Research Day 2023
No abstract provided.
Endobronchial Ultrasound Diagnosis Of A Malignant Superior Vena Cava Tumor Thrombus Extending Into The Right Atrium: An Unusual Cause Of Recurrent Syncope.,
2023
HCA Healthcare
Endobronchial Ultrasound Diagnosis Of A Malignant Superior Vena Cava Tumor Thrombus Extending Into The Right Atrium: An Unusual Cause Of Recurrent Syncope., Larissa Check, Ariba Naz, Richard Duff
South Atlantic Division GME Research Day 2023
No abstract provided.
Maternal Mirror Syndrome As A Consequence Of Fetal Sacrococcygeal Teratoma: A Case Report And Literature Review,
2023
HCA Healthcare
Maternal Mirror Syndrome As A Consequence Of Fetal Sacrococcygeal Teratoma: A Case Report And Literature Review, Ali Farris, Andrew Royek, Kaitlyn Dorsey
South Atlantic Division GME Research Day 2023
No abstract provided.
Pericardial Disease In Metastatic Uterine Carcinosarcoma,
2023
HCA Healthcare
Pericardial Disease In Metastatic Uterine Carcinosarcoma, Dalena Thai, Mario Lavelanet, Mark Stine
West Florida Division GME Research Day 2023
No abstract provided.
Follicular Lymphoma Presenting As A Small Bowel Obstruction: A Case Report,
2023
HCA Healthcare
Follicular Lymphoma Presenting As A Small Bowel Obstruction: A Case Report, Erica Roma, Kelsey Staudinger, Emmett Mcguire, Katrina Lancaster Shorts
Continental, MidAmerica, & Mountain Divisions GME Research Day 2023
No abstract provided.
An Unwanted Neighbor: Contiguous Spread Of Colonic Adenocarcinoma,
2023
HCA Healthcare
An Unwanted Neighbor: Contiguous Spread Of Colonic Adenocarcinoma, Andrew Ondracek, Joshua Wais, Nimal Patel
West Florida Division GME Research Day 2023
No abstract provided.
A Rare Case Of Obstructive Primary Squamous Cell Carcinoma Of The Sigmoid Colon,
2023
HCA Healthcare
A Rare Case Of Obstructive Primary Squamous Cell Carcinoma Of The Sigmoid Colon, Corbin Stephens, Alexandria Dennison, Syed Jafri
Continental, MidAmerica, & Mountain Divisions GME Research Day 2023
No abstract provided.
A Case Of Recurring Gastrointestinal Stromal Tumor While On Imatinib,
2023
HCA Healthcare
A Case Of Recurring Gastrointestinal Stromal Tumor While On Imatinib, Corbin Stephens, Alexandria Dennison, Syed Jafri
Continental, MidAmerica, & Mountain Divisions GME Research Day 2023
No abstract provided.
Understanding And Targeting The Tph1-Serotonin-Htr3a Axis In Small Cell Lung Cancer,
2023
University of Kentucky
Understanding And Targeting The Tph1-Serotonin-Htr3a Axis In Small Cell Lung Cancer, Yanning Hao
Theses and Dissertations--Toxicology and Cancer Biology
Small cell lung cancer (SCLC), which accounts for 10-15% of all lung cancer, is the most malignant type that tends to grow fast and spread in its early stages. The 5-year survival rate remains low at 6% overall. Thus, new therapeutic methods and pharmacological targets for SCLC patients are urgently needed. We present novel data indicating that the synthesis of serotonin is upregulated in SCLC compared to normal bronchial epithelial cells and non-small cell lung cancer. Serotonin signaling plays a critical role in various physiological and pathological processes. However, its contribution to SCLC development has not been well understood. The …
Identification Of Novel Biosynthetic Gene Clusters Encoding For Polyketide/Nrps-Producing Chemotherapeutic Compounds From Marine-Derived Streptomyces Hygroscopicus From A Marine Sanctuary,
2023
University of New Hampshire, Durham
Identification Of Novel Biosynthetic Gene Clusters Encoding For Polyketide/Nrps-Producing Chemotherapeutic Compounds From Marine-Derived Streptomyces Hygroscopicus From A Marine Sanctuary, Hannah Ruth Flaherty
Honors Theses and Capstones
Nearly one out of six deaths in 2020, around ten million people, were caused by cancer, making it a leading cause of death worldwide (WHO, 2022). This major public health issue, in addition to the rise of multidrug-resistant (MDR) pathogens, provides a high demand for the discovery of new pharmaceutical drugs to be used clinically to treat these conditions. The Streptomyces genus accounts to produce 39% of all microbial metabolites currently approved for human health, indicating its potential as an important species to study for antimicrobial and anticancer agents. The long linear genome of Streptomyces contains specialized sequences known as …
Prostate Cancer Aggressiveness And Financial Toxicity Among Prostate Cancer Patients,
2023
LSU Health Sciences Center - New Orleans
Prostate Cancer Aggressiveness And Financial Toxicity Among Prostate Cancer Patients, Madhav Kc, Evrim Oral, Ariane L. Rung, Edward Trapido, Laura S. Rozek, Elizabeth T.H. Fontham, Jeannette T. Bensen, Laura Farnan, Susan E. Steck, Lixin Song, James L. Mohler, Saira Khan, Sanah Vohra, Edward S. Peters
School of Public Health Faculty Publications
Introduction: Financial toxicity (FT) is a growing concern among cancer survivors that adversely affects the quality of life and survival. Individuals diagnosed with aggressive cancers are often at a greater risk of experiencing FT. The objectives of this study were to estimate FT among prostate cancer (PCa) survivors after 10−15 years of diagnosis, assess the relationship between PCa aggressiveness at diagnosis and FT, and examine whether current cancer treatment status mediates the relationship between PCa aggressiveness and FT. Methods: PCa patients enrolled in the North Carolina-Louisiana Prostate Cancer Project (PCaP) were recontacted for long-term follow-up. The prevalence of FT in …
The Development And Characterization Of Nanobodies Specific To Protein Tyrosine Phosphatase 4a3 (Ptp4a3/Prl-3) To Dissect And Target Its Role In Cancer.,
2023
University of Kentucky
The Development And Characterization Of Nanobodies Specific To Protein Tyrosine Phosphatase 4a3 (Ptp4a3/Prl-3) To Dissect And Target Its Role In Cancer., Caroline Smith
Theses and Dissertations--Molecular and Cellular Biochemistry
Protein Tyrosine Phosphatase 4A3 (PTP4A3 or PRL-3) is an oncogenic dual-specificity phosphatase that drives tumor metastasis, promotes cancer cell survival, and is correlated with poor patient prognosis in a variety of solid tumors and leukemias. The mechanisms that drive PRL-3’s oncogenic functions are not well understood, in part due to a lack of research tools available to study this protein. The development of such tools has proven difficult, as the PRL family is ~80% homologous and the PRL catalytic binding pocket is shallow and hydrophobic. Currently available small molecules do not exhibit binding specificity for PRL-3 over PRL family members, …
