Neoplasms Commons^™

Risk Of Colorectal And Gastrointestinal Neoplasia In Inflammatory Bowel Disease Treated With Infliximab Versus Vedolizumab And Ustekinumab: A 5-Year Multicenter Retrospective Cohort Study, Jashanveer S. Johal, Archana Salek, Mahmoud Al-Bataineh, Bianca Patel, Abdallah Hussein, Om Patel, Jason Hyman, Yecheskel Schneider

Rowan-Virtua Research Day

Background: Inflammatory bowel disease (IBD) confers elevated colorectal cancer (CRC) risk, but comparative long-term neoplastic risks between anti-TNF and gut-selective or IL-12/23–targeted biologics remain incompletely defined. We evaluated 5-year risks of CRC and GI neoplasia in IBD patients treated with infliximab versus vedolizumab and ustekinumab.

Methods: Using the TriNetX federated research network, two parallel 5-year propensity score–matched cohort analyses were conducted among adults with Crohn's disease or ulcerative colitis initiating infliximab, vedolizumab, or ustekinumab between 2018–2024. Patients with prior CRC, colectomy, or baseline comparator biologic exposure were excluded. The infliximab–vedolizumab analysis matched 13,111 patients per cohort; the infliximab–ustekinumab analysis matched …

Case Report: Primary Appendiceal Cancer Presenting As Acute Appendicitis, Armeet Singh, Wayne Tamaska, James Espinosa, Alan Lucerna

Rowan-Virtua Research Day

We report a case of a 46‐year‐old male who presented to the emergency department with right lower quadrant abdominal pain and was initially suspected to have acute appendicitis. Further evaluation and surgical pathology revealed primary appendiceal adenocarcinoma. Appendiceal cancer is rare and often presents with nonspecific symptoms that mimic common abdominal conditions such as appendicitis or diverticulitis. Early diagnosis can be challenging, and many cases are discovered incidentally during surgery or imaging for suspected appendicitis. This case highlights the importance of maintaining a broad differential diagnosis for right lower quadrant pain.

An Elusive Diagnosis: Pheochromocytoma Presenting With Hyperglycemia And Hypertensive Crisis, Tucker Ledo

Rowan-Virtua Research Day

Pheochromocytoma is a rare catecholamine-secreting tumor that can present with a wide range of nonspecific symptoms, often mimicking more common medical conditions and making early diagnosis difficult. We report the case of a 40-year-old female with a history of hypertension and prediabetes who presented to the emergency department with hyperglycemia following an episode of lightheadedness. This case highlights the diagnostic challenge of pheochromocytoma in the emergency department, where initial symptoms may be subtle and easily attributed to more common conditions such as hypertension, diabetes, or menopause. Recognition of episodic sympathomimetic symptoms and unexplained hypertensive crises should prompt consideration of pheochromocytoma …

Polypoid Endometriosis With Endometroid Intraepithelial Neoplasia Mimicking Malignancy, Austin T. Jones, Charles M. Quick, Monique A. Spillman

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

Carcinoma Of The Bladder Diagnosed Incidentally Following Cesarean Section, Fatima Hussain, Mimi Rogers

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

Case Report Of Carcinosarcoma Of The Ampulla Of Vater With A Monoclonal Histologic Variant, Peter D. Park, Christopher Oxner

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

Rare Clinical Presentation Of Primary Cutaneous Diffuse Large B-Cell Lymphoma (Pcdlbcl), Germinal Center B-Cell Subtype (Gcb), Confined To The Scalp, Anabel Al Abdallah, Angelo Piazza Ortiz, Joshua Rodriguez, Juan Herrada

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

A Rare Complication Of Leukemic Retinopathy Secondary To Chronic Myeloid Leukemia In Blast Phase, Waleed S. Malik, Vinh Ngo, Kuljot Bansi

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

Organ Function Over Genotype: A Clinical Lesson From Multiple Myeloma With Severe Systemic Al Amyloidosis, Anabel Al Abdallah, Aasia Khan

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

Recurrent Molar Pregnancy – A Case Report, Jayce Jaynes, Sarina Garcia, Dorovenia Hawkins-Koch

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

A Unique Case Of Tumor Thrombus In The Superior Vena Cava (Svc), John Leece, Juan Rodriguez

Central & West Texas and San Antonio GME Research Day 2026

No abstract provided.

Examining The Benefits Of A Standardized Protocol For Hyperglycemia Screening In Adult Oncology Patients: A Pilot Study, Alexa Dashko

Pacific Journal of Health

Many individuals receiving cancer directed therapy are at risk of developing hyperglycemia and new, or worsening of, diabetes due to location of their cancer, treatment regimen, and/or prolonged use of steroids. Research shows that uncontrolled hyperglycemia can have detrimental effects on individuals’ response to cancer therapy, treatment associated toxicities, quality of life and overall mortality. Despite extensive research identifying the need for routine monitoring and management of hyperglycemia in oncology patients, medical societies have yet to establish formal screening guidelines for practitioners. The aim of this pilot study was to examine the outcomes of establishing a protocol for screening and …

The Use Of Large Language Models In Enhancing Patient Education Materials For Pancreatic Neuroendocrine Tumors, Brendan Dolan, Aniela Crayton, Emerson Woodbury, Miguel Tzita, Eliza Beal Md, Gregory Dyson Phd

Medical Student Research Symposium

Background:

Incidence and prevalence of Pancreatic Neuroendocrine Tumors (PNETs) has increased in recent years. More than half of American adults endorse utilizing the internet within the past year to search for medical information. This study aims to investigate the use of Large Language Models (LLMs), a popular type of artificial intelligence, to improve the efficacy of online patient education materials (oPEMs) in providing accurate and digestible information to patients with a PNET diagnosis.

Methods: Content from 36 web pages related to PNET was transferred to two popular LLMs, Chat GPT and Google Gemini, with the prompt “rewrite the following text …

Investigating Corollaries Between Streptococcus Gallolyticus Subsp. Gallolyticus Virulence And Colorectal Cancer, Tyler G. Myers

Pursuit - The Journal of Undergraduate Research at The University of Tennessee

Streptococcus gallolyticus subsp. gallolyticus (Sgg) is a gram-positive, non-beta-hemolytic bacterium that belongs to the Lancefield group D of streptococcal pathogens. For the past several decades, associations between Sgg bacteremia and colorectal cancer (CRC) have been apparent, with gastroenterologists routinely recommending colonoscopies for positive cases of Sgg in either blood or stool samples. However, current research has not wholly established whether Sgg acts as a causative agent of CRC or if pre-existing cancers make the lumen of the colon more hospitable to its colonization. Regardless, Sgg has been implicated in the modulation of host inflammatory pathways and subsequent remodeling …

Defining A Multi-Omic, Ai-Enabled Stool Screening Paradigm For Colorectal Cancer: A Consensus Framework For Clinical Translation, Arturo Loaiza-Bonilla, Yan Leyfman, Viviana Cortiana, Rhys Crawford, Shivani Modi

Einstein Health Papers

Colorectal cancer (CRC) develops through both conventional adenoma-carcinoma and serrated neoplasia pathways, yet noninvasive screening still under-detects the advanced precursor lesions that enable true cancer prevention. Stool-based screening reduces CRC mortality, but its preventive impact remains constrained by limited detection of advanced precancerous lesions (APLs), including advanced adenomas and sessile serrated lesions. Next-generation multitarget stool DNA assays (mt-sDNA; e.g., Cologuard Plus) have established high sensitivity for CRC and specificity approaching 94%, leaving improved APL detection as the principal opportunity for innovation. This review presents a consensus framework for a multi-omic stool screening paradigm that integrates host epigenetic markers (DNA methylation) …

Metabolic Responses To Freund’S Adjuvants And Oncolytic Viruses: Implications On Vaccines And Tumor Immunity, Kiruthiga Mone

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Freund’s adjuvants have been extensively used in experimental research, and they modulate immune responses through various mechanisms. While both complete Freund’s adjuvant (CFA) and incomplete Freund’s adjuvant (IFA) contain the same mineral oil base, CFA contains the killed extract of Mycobacterium tuberculosis (M. tb) as an additional ingredient. Because the CFA contains mycobacterial content similar to that of Bacillus Calmette-Guérin (BCG), which induces trained immunity (TI), we tested the hypothesis that CFA may elicit TI-like features. To test this hypothesis, we investigated the metabolic and epigenetic reprogramming induced by CFA, with IFA and BCG as controls, in inbred …

Nursing Practice In Cancer Treatment Decision Making Among Older Adults: A Scoping Review On Behalf Of The International Society Of Geriatric Oncology Nursing, Allied Health, And Scientists Interest Group, Fay J. Strohschein, Hanneke Van Der Wal-Huisman, K. Alix Hayden, Kristen R. Haase, Michelle Hannan, Cindy Kenis, Juan Li, Nikita Nikita, Sophie Pilleron, Tracy Ruegg, Heike Schmidt, Anke Steckelberg, Cassandra Vonnes, Martine Puts

Department of Medical Oncology Faculty Papers

INTRODUCTION: Cancer treatment decision making (CTDM) presents important challenges among older adults due to variation in health and functional status, presence of comorbidities, differing goals/values, quality and quantity of life considerations, and limited inclusion in clinical trials. Nursing standards and guidelines call for competence in supporting CTDM and nurses advocate for greater involvement. However, clear understanding of the existing evidence to inform nursing practice is lacking. We aimed to map and synthesize evidence that provides insight into nursing practice in CTDM among older adults, with attention to nursing roles, required skills and competencies, potential barriers and facilitators, and outcomes studied. …

Outcomes Of Radiation Integrated With T-Cell-Engaging Bispecific Antibodies In Relapsed/Refractory Multiple Myeloma, Heta Patel, Harper Hubbeling, Kyle Yu, Maribel Carpenter, Michael Lariviere, John Plastaras, Adam Cohen, Shivani Kapur, Dan Vogl, Adam Waxman, Edward Stadtmauer, Alfred Garfall, Sandra Susanibar-Adaniya

Student Papers, Posters & Projects

No abstract provided.

The Ninth Chondroid Syringoma With Bone Formation: A Case Report, Mojan Deriss, Kelsey Ouyang, Parnian Alizadeh, Amir Qorbani, Voicu S. Ciobanu

Annual Research Symposium

This poster presents a rare case of chondroid syringoma with ossification, representing only the ninth reported instance of bone formation within this adnexal tumor. The report describes a slowly enlarging facial nodule in a 34-year-old male, detailing clinical presentation, surgical excision, and histopathologic findings. Microscopy revealed characteristic epithelial cords and tubules within a myxoid stroma, along with mature lamellar bone formation, confirming the diagnosis. The case expands the known morphologic spectrum of chondroid syringomas and highlights the importance of considering this entity in the differential diagnosis of benign facial masses, particularly when unusual features such as ossification are present.

Management Of Acute Myeloid Leukemia: A Review, Chetan Jeurkar, Lana King, David Baek, Lindsay Wilde, Gina Keiffer, Margaret Kasner

Kimmel Cancer Center Faculty Papers

Background/Objectives: Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy with historically poor outcomes, particularly among older adults and patients harboring high-risk molecular features. Advances in genomic profiling have enabled the development of targeted therapies, reshaping treatment algorithms beyond conventional cytarabine-anthracycline induction and hypomethylating agent-based regimens. This review summarizes current evidence and emerging therapeutic strategies across four evolving areas: menin inhibition, FLT3 inhibition, IDH inhibition and treatment approaches for TP53-mutated AML. Methods: We reviewed published clinical trials, preclinical studies, and ongoing clinical trials evaluating targeted therapies in AML. Emphasis was placed on agents with regulatory approval or substantial clinical development, …