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Digestive System Diseases Commons

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1,349 full-text articles. Page 3 of 66.

Pediatric Inflammatory Bowel Disease Tissue Classification From Pathology Slide Images: Detecting Phenotypes Using Computer Vision, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Brian Rubio, Ghislaine Barrigan, Kenneth Grant 2026 Children’s Health Orange County (CHOC)

Pediatric Inflammatory Bowel Disease Tissue Classification From Pathology Slide Images: Detecting Phenotypes Using Computer Vision, Chloe Martin-King, Ali Nael, Louis Ehwerhemuepha, Blake Calvo, Quinn Gates, Jamie Janchoi, Elisa Ornelas, Melissa Perez, Andrea Venderby, John Miklavcic, Peter Chang, Aaron Sassoon, Brian Rubio, Ghislaine Barrigan, Kenneth Grant

Food Science Faculty Articles and Research

Background and Aims

With the advent of computer vision algorithms, we hypothesize that histopathology images from endoscopic biopsies may be utilized for automated classification of histologic phenotypes, thus guiding Crohn’s disease and ulcerative colitis diagnosis and treatment. The aim of our study is to assess whether artificial intelligence can be used to improve pediatric inflammatory bowel disease outcomes by aiding pathologists with accurate detection of abnormal tissue sections.

Methods

Three two-dimensional (2D) convolutional neural networks with multiple instance learning were developed to classify histopathology tissue sections as normal vs abnormal and as containing active inflammation and/or chronic changes/architectural distortion.

Results …


Post-Traumatic Rupture Of Primary Solid Pseudopapillary Epithelial Neoplasm (Spen) Of The Pancreas In A Male Adolescent: A Case Report, Paulo Castro, Heather Hartman, Yashasvi Shukla, Michael Moore, Dennis Drehner, Harish Lavu 2026 Thomas Jefferson University

Post-Traumatic Rupture Of Primary Solid Pseudopapillary Epithelial Neoplasm (Spen) Of The Pancreas In A Male Adolescent: A Case Report, Paulo Castro, Heather Hartman, Yashasvi Shukla, Michael Moore, Dennis Drehner, Harish Lavu

Department of Surgery Faculty Papers

Introduction Solid pseudopapillary epithelial neoplasm (SPEN) is a rare pancreatic tumor that typically presents in adult women and is usually asymptomatic. Case presentation A 12-year-old male presented to the emergency department with worsening abdominal pain one day after suffering mild abdominal trauma during a soccer match. Physical exam showed diffuse abdominal tenderness and guarding. CT abdomen with IV contrast showed a heterogeneous, round structure adjacent to the pancreatic tail with mass effect upon the spleen. MRI abdomen revealed a “claw sign” of pancreatic tissue surrounding the structure, suggesting a an underlying pancreatic mass with capsular rupture measuring 8.3 x 8.1 …


The Role Of Extracellular Vesicles As Diagnostic Tools In Gut-Brain Axis Disorders, Patricia Marçal da Costa, Paulo Iury Gomes Nunes, Gabriella Cunha Vieira Ciurleo, José Wagner Leonel Tavares Junior, Pedro Braga Neto, Ludmila Belayev, Reinaldo Barreto Oriá 2026 Federal University of Ceará, Fortaleza, Brazil

The Role Of Extracellular Vesicles As Diagnostic Tools In Gut-Brain Axis Disorders, Patricia Marçal Da Costa, Paulo Iury Gomes Nunes, Gabriella Cunha Vieira Ciurleo, José Wagner Leonel Tavares Junior, Pedro Braga Neto, Ludmila Belayev, Reinaldo Barreto Oriá

School of Graduate Studies Faculty Publications

The gut–brain axis represents a dynamic two-way signaling network whose dysregulation has been implicated in a wide range of neurogastrointestinal disorders. In this context, extracellular vesicles (EVs) have emerged as critical mediators of intercellular signaling and as promising non-invasive biomarkers. Derived from host and microbial cells, EVs carry bioactive cargo—including proteins, lipids, nucleic acids, and metabolites—that reflect the physiological or pathological state of their cells of origin. Their ability to cross biological barriers, such as the blood–brain barrier, underscores their potential for diagnosing and monitoring gut–brain axis dysfunctions. In this mini-review, we integrate microbial and brain-derived EVs within the framework …


Another Gastric Band Complication: Acute Appendicitis, Dustin Williamson, Naveed Ismail, John Weaver 2026 HCA Healthcare

Another Gastric Band Complication: Acute Appendicitis, Dustin Williamson, Naveed Ismail, John Weaver

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Biliary Obstruction From An Unexpected Source, Max DiNicola, Trevor Link, Derek Welch 2026 HCA Healthcare

Biliary Obstruction From An Unexpected Source, Max Dinicola, Trevor Link, Derek Welch

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Spontaneous Pneumoperitoneum Presenting As An Acute Abdomen, Madison McInnis, Megan Tierney, Kaysie Banton 2026 HCA Healthcare

Spontaneous Pneumoperitoneum Presenting As An Acute Abdomen, Madison Mcinnis, Megan Tierney, Kaysie Banton

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Cecal Volvulus In The Setting Of Situs Inversus Totalis: A Rare Case Report, Alexandra Moody, Josie Bjorklund 2026 HCA Healthcare

Cecal Volvulus In The Setting Of Situs Inversus Totalis: A Rare Case Report, Alexandra Moody, Josie Bjorklund

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Diplopia In Metastatic Hepatocellular Carcinoma With Spread To The Sphenoid Sinus, Elena Salikhova-Neace, Anna Belits, Petros Keoseyan, Ethan McCarty, Judd Jensen, Katrina Lancaster-Shorts, Emily Lampe 2026 HCA Healthcare

Diplopia In Metastatic Hepatocellular Carcinoma With Spread To The Sphenoid Sinus, Elena Salikhova-Neace, Anna Belits, Petros Keoseyan, Ethan Mccarty, Judd Jensen, Katrina Lancaster-Shorts, Emily Lampe

Continental and Mountain Divisions GME Resarch Day 2026

No abstract provided.


Surgical Approach To Colon Resection With Colostomy Creation Influences Reversal Rates And Postoperative Outcomes: A Retrospective Longitudinal Analysis, Benjamin Perkins, Ena Novakovic-Bennet, Salvatore Caleb Jerris, Alyssa Kozlowski, Andrew Schlussel 2026 HCA Healthcare

Surgical Approach To Colon Resection With Colostomy Creation Influences Reversal Rates And Postoperative Outcomes: A Retrospective Longitudinal Analysis, Benjamin Perkins, Ena Novakovic-Bennet, Salvatore Caleb Jerris, Alyssa Kozlowski, Andrew Schlussel

South Atlantic Division GME Research Days 2026

No abstract provided.


Antagonistic Effects Of Glucagon And Insulin On 5-Fluorouracil Efficacy In Colorectal Cancer, Gabriel M. Randolph, Andrea Florian 2026 Belmont University

Antagonistic Effects Of Glucagon And Insulin On 5-Fluorouracil Efficacy In Colorectal Cancer, Gabriel M. Randolph, Andrea Florian

SPARK Symposium Presentations

Prior research on the combined effects of insulin and glucagon with low-dose chemotherapy in cancer treatment has yielded contradictory conclusions. Insulin potentiation therapy (IPT), a longstanding but understudied approach, is broadly claimed to enhance chemotherapeutic efficacy; however, it has also been characterized as pseudoscience lacking physiological merit. Adding further complexity, glucagon, insulin's antagonist hormone, has been shown to produce anti-cancer effects when combined with chemotherapeutic agents. The present study aims to observe the individual effects of both hormones on colorectal cancer cells in combination with 5-Fluorouracil (5-FU), to clarify their respective roles in combination therapy. Through the modulation of both …


Oral N-Acetylcysteine In Hepatitis C - Induced Acute Liver Injury: A Case Report, Mohammed Irfan Khan, Shuchita Jhaveri, Renu Thomas, Kevin Garnepudi, Galvin Dhaliwal, Ahmed Ouni, Shane P. Sweeney, Julian Nguyen 2026 HCA Healthcare

Oral N-Acetylcysteine In Hepatitis C - Induced Acute Liver Injury: A Case Report, Mohammed Irfan Khan, Shuchita Jhaveri, Renu Thomas, Kevin Garnepudi, Galvin Dhaliwal, Ahmed Ouni, Shane P. Sweeney, Julian Nguyen

Gulf Coast Division GME Research Day 2026

No abstract provided.


Immune Checkpoint Inhibitor-Induced Colitis, Alexis Lopez Cruz, Praise Ohabor, Zuhair Ali 2026 HCA Healthcare

Immune Checkpoint Inhibitor-Induced Colitis, Alexis Lopez Cruz, Praise Ohabor, Zuhair Ali

Gulf Coast Division GME Research Day 2026

No abstract provided.


Colonic Perforation In A Patient On Glp-1 Agonist Therapy: A Case Report, Mohammed Irfan Khan, Shuchita Jhaveri, Azad Patel, Bilal Ashraf, Ahmed Ouni, John Paek, Sivatej Sarva 2026 HCA Healthcare

Colonic Perforation In A Patient On Glp-1 Agonist Therapy: A Case Report, Mohammed Irfan Khan, Shuchita Jhaveri, Azad Patel, Bilal Ashraf, Ahmed Ouni, John Paek, Sivatej Sarva

Gulf Coast Division GME Research Day 2026

No abstract provided.


Herbal Healing Gone Wrong: Herb-Induced Hepatitis Masquerading As Autoimmune Liver Disease, Sacha Saba, Mahi Basra, Andrew Ondracek, Roxana Bodin 2026 HCA Healthcare

Herbal Healing Gone Wrong: Herb-Induced Hepatitis Masquerading As Autoimmune Liver Disease, Sacha Saba, Mahi Basra, Andrew Ondracek, Roxana Bodin

West Florida Division GME Research Day 2026

No abstract provided.


Artificial Intelligence-Based Prediction Of Mortality In Acute-On-Chronic Liver Failure: A Systematic Review Of Prognostic Models, Pradeep Rajbhandari, Lawrence San Jose, Mohammad Mahfouz, Michael Waxman 2026 HCA Healthcare

Artificial Intelligence-Based Prediction Of Mortality In Acute-On-Chronic Liver Failure: A Systematic Review Of Prognostic Models, Pradeep Rajbhandari, Lawrence San Jose, Mohammad Mahfouz, Michael Waxman

MidAmerica Division GME Healthcare Symposium 2026

No abstract provided.


Redefining Resectability In Pancreatic Cancer: A Modified Appleby And Radical Antegrade Modular Pancreatosplenectomy Procedure With Concomitant Left Lateral Sectionectomy In A Patient With Replaced Right And Left Hepatic Arteries, Monica Sciturro, Nada Belal, Jamii St. Julien 2026 HCA Healthcare

Redefining Resectability In Pancreatic Cancer: A Modified Appleby And Radical Antegrade Modular Pancreatosplenectomy Procedure With Concomitant Left Lateral Sectionectomy In A Patient With Replaced Right And Left Hepatic Arteries, Monica Sciturro, Nada Belal, Jamii St. Julien

West Florida Division GME Research Day 2026

No abstract provided.


Insidious Abdominal Pain Masked By Kratom Abuse; A Case Of Lynch Syndrome, Grant Read, Khloe Gu, Jessica Klingensmith, Ameet Patel 2026 HCA Healthcare

Insidious Abdominal Pain Masked By Kratom Abuse; A Case Of Lynch Syndrome, Grant Read, Khloe Gu, Jessica Klingensmith, Ameet Patel

West Florida Division GME Research Day 2026

No abstract provided.


Potassium Competitive Acid Blockade After Gastric Esd: Does Vonoprazan Outperform Ppis: A Systematic Review And Meta-Analysis, Shavya R. Ginnaram, Pradeep Yarra, Gnanashree Dharmarpandi, Rajat Garg, Sreekanth Chandrupatla 2026 HCA Healthcare

Potassium Competitive Acid Blockade After Gastric Esd: Does Vonoprazan Outperform Ppis: A Systematic Review And Meta-Analysis, Shavya R. Ginnaram, Pradeep Yarra, Gnanashree Dharmarpandi, Rajat Garg, Sreekanth Chandrupatla

West Florida Division GME Research Day 2026

No abstract provided.


Pyoderma Gangrenosum As An Initial Presentation Of Rheumatoid Arthritis & Inflammatory Bowel Disease, Julian Reoyo, Jennifer Cucalon, Milton Alexis Torres, Toni Feghali, Francia Guerrero, Joseph Pino, Shahid Sulaiman 2026 HCA Healthcare

Pyoderma Gangrenosum As An Initial Presentation Of Rheumatoid Arthritis & Inflammatory Bowel Disease, Julian Reoyo, Jennifer Cucalon, Milton Alexis Torres, Toni Feghali, Francia Guerrero, Joseph Pino, Shahid Sulaiman

West Florida Division GME Research Day 2026

No abstract provided.


Case Report: Primary Recurrent Gallstones Following Cholecystectomy, Gabriel Noguera, Nimal Patel 2026 HCA Healthcare

Case Report: Primary Recurrent Gallstones Following Cholecystectomy, Gabriel Noguera, Nimal Patel

West Florida Division GME Research Day 2026

No abstract provided.


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