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The Influence Of Flavor On The Abuse Liability Of A Heated Tobacco Product And Its Feasibility As A Menthol Cigarette Substitute, Augustus White 2024 Virginia Commonwealth University

The Influence Of Flavor On The Abuse Liability Of A Heated Tobacco Product And Its Feasibility As A Menthol Cigarette Substitute, Augustus White

Theses and Dissertations

Heated Tobacco Products (HTPs) purport to expose people that use cigarettes to fewer of the harmful or potentially harmful constituents of tobacco while still delivering reinforcing amounts of nicotine (Auer, Concha-Lozano et al., 2017). An exemplar of the HTP class, IQOS, and its three varieties of “HeatSticks” have been authorized by the Food and Drug Administration (FDA) as “Modified Risk Tobacco Products” (MRTP). However, as the FDA is planning to ban menthol as a characterizing flavor in cigarettes, questions remain regarding whether characterizing flavors should be permitted in HTPs (FDA, 2022e). New evidence regarding HTP abuse liability (i.e., the likelihood …


Neural Hyperactivity During Value-Based Decision-Making In People With Daily/Near Daily Cannabis Use, Miranda Ramirez 2024 University of Kentucky

Neural Hyperactivity During Value-Based Decision-Making In People With Daily/Near Daily Cannabis Use, Miranda Ramirez

Theses and Dissertations--Psychology

Value-based decision-making involves the coordinated effort of multiple brain regions to guide future choices based on past experiences. These processes are disrupted in cannabis use disorder, where individuals continue to use cannabis despite negative consequences. Reinforcement learning (RL) paradigms can be used to capture changes in the value of available options and may inform how the brain is impacted by frequent cannabis use. This study combined fMRI with behavioral modeling of probabilistic choice task data to compare value-based choices between young adults reporting daily/near daily cannabis use (CAN) and controls (CTRL). Participants selected one of two options reinforced ($0.25) at …


Is Trust A Zero-Sum Game? What Happens When Institutional Sources Get It Wrong, Andrew Dawson 2024 Wilfrid Laurier University

Is Trust A Zero-Sum Game? What Happens When Institutional Sources Get It Wrong, Andrew Dawson

Theses and Dissertations (Comprehensive)

In the wake of the COVID-19 pandemic, trust in mainstream institutions is on the decline while people are increasingly turning to alternative media and conspiracy theories. Previous research has suggested that these trends may be linked, but the exact nature of the relationship is unclear. In a fractured informational environment, is trust a neutral process, where each source is judged independently, or is it in fact a zero-sum competition, where a loss for one side is a gain for the other? Across three experimental studies (N = 2,951) we examined how people react when a source makes a serious error, …


Social Coordination Maintained By Progressive Delay Of Coordination-Dependent Reinforcement, Firdavs Khaydarov 2024 West Virginia University

Social Coordination Maintained By Progressive Delay Of Coordination-Dependent Reinforcement, Firdavs Khaydarov

Graduate Theses, Dissertations, and Problem Reports (ETD)

The purpose of the present investigation was to examine coordination maintained by the progressive delay of coordination-dependent reinforcement and to compare the effects of unsignaled and signaled delays on coordination maintenance. In Experiment 1, coordination was examined using two multiple schedules in which two components alternated daily. One of the multiple schedules included progressive-delay (Component 1) and a yoked-interval (Component 2) schedule of coordination-dependent reinforcement in the two components. The other multiple schedule contained a progressive-delay (Component 1) and a yoked-interval (Component 2) schedule of coordination-independent reinforcement in the two components. Component 1 always preceded Component 2, and interreinforcer intervals …


An Evaluation Of A Human-Operant Effort Manipulation And Effects Of Effort Disparity On Renewal, Haleh Amanieh 2024 WVU

An Evaluation Of A Human-Operant Effort Manipulation And Effects Of Effort Disparity On Renewal, Haleh Amanieh

Graduate Theses, Dissertations, and Problem Reports (ETD)

The relative effort of target and alternative responses during treatments using differential reinforcement of alternative behavior may impact the likelihood that a previously reduced target response will reemerge following a context change (i.e., “renewal”). The purpose of this study was to evaluate the role of an effort disparity between target and alternative responses in a human-operant arrangement. Eighteen college students clicked on one (Experiment 1) or two (Experiment 2) circles moving on a computer screen for points. In Experiment 1, the speed of the circle was manipulated as an index of effort such that three circle speeds (i.e., 50, 100, …


Making Something Out Of Nothing: Immobility As An Operant, Kaʻala K. Bajo 2024 West Virginia University

Making Something Out Of Nothing: Immobility As An Operant, KaʻAla K. Bajo

Graduate Theses, Dissertations, and Problem Reports (ETD)

The tradition of research in the experimental analysis of behavior generally emphasizes the analysis of overt, discrete responses such as lever presses or key pecks. Reflecting this emphasis, definitions of behavior involve the observable action or movement of an organism through space. Although continuous responses involving little to no movement, such as “holding still” or “immobility”, fall outside these definitions, immobility is a form of continuous, operant responding that can be learned and experimentally controlled. Three experiments were conducted to investigate parameters surrounding immobility as an operant. In Experiment 1, immobility in the form of platform-standing bouts was shaped and …


Effects Of Probabilistic Win-Paired-Cue Delivery On Loss Trials On Risky Choice In Rats, Connor M. Lambert 2024 West Virginia University

Effects Of Probabilistic Win-Paired-Cue Delivery On Loss Trials On Risky Choice In Rats, Connor M. Lambert

Graduate Theses, Dissertations, and Problem Reports (ETD)

Problem gambling, or Gambling Disorder, is a behavioral disorder that affects 2.5% of the U.S. population and can result in detriments to physical, mental, and financial well-being. Electronic gambling machines (e.g., slot machines, video poker, pachinko) may be more addictive than other forms of gambling (e.g., table games, sports betting). Electronic gambling machines present a series of audiovisual stimuli concurrently with winning and some losing outcomes. Previous research in human and non-human animals has found increased levels of risky choice when audiovisual stimuli are presented with wins compared to their absence. The present study was arranged to evaluate how a …


Is Racial Diversity Important When Applying To Jmu Pa Program?, Gaelyn E Young, Deonte J. Hope 2023 James Madison University

Is Racial Diversity Important When Applying To Jmu Pa Program?, Gaelyn E Young, Deonte J. Hope

Physician Assistant Capstones, 2020-current

The Physician Assistant profession is predominantly female and Caucasian. In order to increase the diversity of the profession at the level of the workforce, it is necessary to examine PA programs' role as the entryway into the profession. To that end, this evaluation aimed at surveying current and future PA students at James Madison University to understand whether racial diversity of both the program's cohort and/or its faculty was a factor in their decision to apply and/or attend the school.


A Psychometric Validation Of The Spanish Translation Of The Coping Inventory In A Latinx Population, Daniela Chavez 2023 The University of Texas Rio Grande Valley

A Psychometric Validation Of The Spanish Translation Of The Coping Inventory In A Latinx Population, Daniela Chavez

Theses and Dissertations

Research efforts to comprehend coping strategies in response to stress within the Latinx/Hispanic community have been limited. The inability to effectively cope with stress can lead to physical and mental health problems in adults. This study aims to test the psychometric properties of the translated version of a recently developed coping assessment, “The Coping Inventory,” to evaluate its validity among Spanish-speaking Latinx individuals. The results indicate that The Coping Inventory demonstrates reliability and validity among this population. These findings can enhance the measurement of coping strategies within the Latinx/Hispanic community, potentially resulting in improved …


Repeated Treatment With 5-Ht1a And 5-Ht1b Receptor Agonists: Evidence Of Tolerance And Behavioral Sensitization, Jordan Taylor 2023 California State University, San Bernardino

Repeated Treatment With 5-Ht1a And 5-Ht1b Receptor Agonists: Evidence Of Tolerance And Behavioral Sensitization, Jordan Taylor

Electronic Theses, Projects, and Dissertations

Serotonin has been found to regulate several cognitive and physiological functions, and its role in depression and other neuropsychiatric disorders has been a focus of research. More specifically, a wealth of research regarding serotonin focuses on serotonergic medications in the treatment of neuropsychiatric disorders, such as depression and anxiety, and stimulates the 5-HT1A and 5-HT1B receptors. Within the last decade, there has been an increase in prescriptions of psychotropic medication for children, however, the efficacy and adverse effects of these drugs have not been evaluated in younger populations. While antidepressants reduce symptoms of depression in adults, they are …


The Effectiveness Of Computerized Neurofeedback As An Accompanying Or Alternative Therapeutic Intervention For Pharmacological Treatment In Improving Attention And Other Symptoms For Children With Attention Deficit Hyperactivity Disorder (Adhd), Eqbal Z. Darandari PhD, Nouf F. Alsultan 2023 King Saud University

The Effectiveness Of Computerized Neurofeedback As An Accompanying Or Alternative Therapeutic Intervention For Pharmacological Treatment In Improving Attention And Other Symptoms For Children With Attention Deficit Hyperactivity Disorder (Adhd), Eqbal Z. Darandari Phd, Nouf F. Alsultan

International Journal for Research in Education

This study aimed to investigate the effectiveness of a treatment program using computerized neuro-feedback in improving attention for children with attention deficit hyperactivity disorder (ADHD). To achieve the aim of the study, the computerized neurofeedback program was applied to (56) children diagnosed with (ADHD), aged between (7-11) years. They were distributed into four groups: the first group was subjected to combined intervention (neurofeedback & pharmacological treatment), the second group was subjected to (neurofeedback only), while the third group was exposed to the intervention using (pharmacological treatment only), and the fourth group was (not exposed to any intervention). Test of Variables …


Sex Differences In Stress Reactivity And Responses To Novelty In The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Alaniz, Nicole Altamirano, Joseph Rafac, Katelynn Renteria, John L. VandeBerg, Mario Gil 2023 The University of Texas Rio Grande Valley

Sex Differences In Stress Reactivity And Responses To Novelty In The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Alaniz, Nicole Altamirano, Joseph Rafac, Katelynn Renteria, John L. Vandeberg, Mario Gil

Research Colloquium

Introduction: Investigating how exposures to stress and novel environments influence behavior is important for translational research that aims to improve mental health. Previous studies have focused on reactions to novelty and revealed changes in defense reactions and exploratory behavior. (Pisula et al., 2012).

Objective: The focus of the present study is to investigate sex differences in behavioral responses to novel environments and restraint stress in the gray short-tailed opossums (Monodelphis domestica). Using the Monodelphis is innovative because it is a non-traditional animal model that is ideal for developmental research.

Methods: Using AnyMaze video tracking software, animals’ behaviors (6 males, 6 …


Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. VandeBerg, Mario Gil 2023 The University of Texas Rio Grande Valley

Sex Differences In Stress Reactivity, Brain Morphology, And Oxytocin In The Hypothalamus Of The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Zacarias, Daniela Rodriguez, Alexandra Chalons, Sasawan Heingraj, Nicole Altamirano, Joseph Rafac, John L. Vandeberg, Mario Gil

Research Colloquium

Understanding the effects of stress on behavior and cognition is important due to its impact on mental health and wellbeing (Schneiderman et al. 2005). Translational animal research can contribute to the development of new treatments that can improve therapeutic outcomes and our understanding of the neurobiology of stress. In the present study, we complement behavioral stress reactivity with immunohistochemical localization of oxytocin in the hypothalamus, a neuropeptide that regulates stress (Neumann & Slattery, 2016). Oxytocin has potential therapeutic use for mental health disorders (Neumann & Slattery, 2016), and the effects of oxytocin seem to be sexually dimorphic (Love, 2018). Using …


The Effect Of Model Size On The Root Mean Square Error Of Approximation (Rmsea): The Nonnormal Case, Yunhang Yin 2023 University of South Carolina

The Effect Of Model Size On The Root Mean Square Error Of Approximation (Rmsea): The Nonnormal Case, Yunhang Yin

Theses and Dissertations

This study aimed to understand the effect of model size on the Root Mean Square Error of Approximation (RMSEA) under nonnormal data. We considered three methods for computing the sample RMSEA and the associated confidence intervals (i.e., the normal theory method [Browne & Cudeck, 1993], the BSL method [Brosseau-Liard, Savalei & Li, 2012], and the Lai method [Lai, 2020]). The performance of the three methods was compared across various model sizes, sample sizes, levels of misspecification, and levels of nonnormality. Results indicated that the normal theory RMSEA should not be used under nonnormal data unless the model size is very …


Neural Correlates Of Audiovisual Integration, Jonathan Conrady 2023 University of South Carolina

Neural Correlates Of Audiovisual Integration, Jonathan Conrady

Theses and Dissertations

Successfully integrating multiple streams of information is paired with a variety of behavioral enhancements. Multisensory research over the past few decades has demonstrated the criticality of spatial proximity and stimulus effectiveness. Here, we focused on the temporal aspects and underlying neural activity of frequency-varying, audiovisual stimuli using scalp recorded electroencephalography (EEG). Our set of stimuli was particularly chosen because humans are most sensitive to the auditory sound and visual spatial frequencies that make up speech. Recent work has shown that audiovisual integration effects of low-level, simple stimuli are largest when both modalities fall within, compared to outside of, their respective …


The Impact Of Biological Sex On Motor Function And Responses To Novel Environments In The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Alaniz, Ismael Perez, Sasawan Heingraj, Katelynn Renteria, Cristian M. Botello, Joseph C. Cantu, John L. VandeBerg, Mario Gil 2023 The University of Texas Rio Grande Valley

The Impact Of Biological Sex On Motor Function And Responses To Novel Environments In The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Alaniz, Ismael Perez, Sasawan Heingraj, Katelynn Renteria, Cristian M. Botello, Joseph C. Cantu, John L. Vandeberg, Mario Gil

Research Symposium

Background: Understanding the different stress reactions in different environments can help us understand stress factors. Studying animal behavior is important for translational research for mental health improvement.

Previous literature has shown that stress is a risk factor for higher cancer incidence and poorer cancer survival. (Klejbor & Turlejski., 2012), as well as mental health outcomes. Understanding of how stress is related to cancer can help improve therapeutic outcomes as preventive measures (Glaser et al., 1987).

Methods: Using the Rota Rod apparatus, 12 animals (3 males, 9 females) were tested at 36 rpm for a maximum of 400 seconds (Madroñal et …


Ufo Witness Testimony (Reliability)--'Flyer', 2023 Cal Poly Humboldt

Ufo Witness Testimony (Reliability)--'Flyer'

The International Journal of Ecopsychology (IJE)

No abstract provided.


You Hurt My Feelings: Autonomic And Behavioral Responses To Social Exclusion And The Moderating Effect Of Psychopathic Traits, Liat Kofler 2023 CUNY Graduate Center

You Hurt My Feelings: Autonomic And Behavioral Responses To Social Exclusion And The Moderating Effect Of Psychopathic Traits, Liat Kofler

Dissertations, Theses, and Capstone Projects

Humans have a fundamental need to form and maintain social connections, and thus experiencing social exclusion is extremely distressing as it threatens this basic human need. Individuals who are socially excluded often respond aggressively, not only towards their ostracizers but also towards innocent bystanders, with ostracism being implicated in extreme acts of violence such as school shootings. However, individual differences in behavior exist within the context of social exclusion as not everyone responds aggressively after being ostracized. Identifying risk factors for retaliatory aggressive behavior following experiences of social exclusion may facilitate the development of targeted interventions aimed at mitigating such …


Attenuated Typicality Effect In Category-Based Inferences: Implications For Autism Spectrum Disorder, Janani Rajagopalan 2023 CUNY Graduate Center

Attenuated Typicality Effect In Category-Based Inferences: Implications For Autism Spectrum Disorder, Janani Rajagopalan

Dissertations, Theses, and Capstone Projects

Individuals diagnosed with Autism Spectrum Disorder (ASD) often encounter challenges in assimilating atypical exemplars into their categorical prototypes, a cognitive hurdle that can impact their interpretative and integrative capacities. Addressing this problem, the present research sought to develop a robust methodological approach to reduce the effect of this disparity. We examined the elements embedded within the category's internal structure, with the intention of experimentally attenuating the pronounced typicality effect, which is often exaggerated in ASD.

Across four experiments, the thesis investigated the cognitive and neural underpinnings that shape the access to the typicality gradient intrinsic to a category's structure. The …


Attention And Task Engagement During Automated Driving, James Richard Unverricht 2023 Old Dominion University

Attention And Task Engagement During Automated Driving, James Richard Unverricht

Psychology Theses & Dissertations

Many young drivers suffer fatal crashes each year in the United States at a rate approximately three times greater than more experienced drivers. Automated driving systems may serve to mitigate young drivers high crash rates but remain underexplored in research. This dissertation project examined the effects of levels of automation and interestingness of auditory clips on latent hazard anticipation in young drivers during simulated driving. Participants drove a vehicle at varying levels of vehicle automation (SAE Level 0, 2, or 3) in simulated scenarios, each containing a latent hazard event during which a boring, neutral, or interesting auditory clip was …


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