Veterinary Medicine Commons^™

Long-Term Clinical Outcome Of Corneal Endothelial Degeneration Managed With Keratoleptynsis In A Chihuahua Dog, Manbok Jeong

The Thai Journal of Veterinary Medicine

A 9-year-old spayed female Chihuahua presented with a 2-month history of progressive corneal edema in the left eye. Slit lamp biomicroscopy showed moderate corneal edema, instability of the axial corneal epithelial surface, and an anterior cortical opacity of the lens. Based on these results, a diagnosis of canine endothelial degeneration was made with the incidental finding of an incipient cataract in the left eye. Keratoleptynsis successfully managed the corneal edema for 28 months after surgery without corneal ulceration. This case study underscores the need for an early surgical approach using keratoleptynsis for dogs with a progressive nature of canine endothelial …

An Undetermined Osteoporotic Disease Managed With Im Rod In A Dog, Hyejong Oh, Byoungho An, Dongwook Kim, Heesoo Ahn, Dongwoo Chang, Gonhyung Kim

The Thai Journal of Veterinary Medicine

Osteoporosis is a systemic bone disorder characterized by decreased bone density, which can weaken bone strength and increase the risk of fractures. Osteogenesis imperfecta (OI), one of the main causes of osteoporosis in children, results in fragile bones and multiple fractures. The present study documented the case of a dog with an undetermined osteoporotic disease managed with intramedullary rod fixation. A 3-month-old intact male Alaskan Malamute dog, weighing 11.6 kg, was presented with lameness in the left pelvic limb. Radiography revealed left pelvic and femoral fractures, and the cortex of the long bones was thin. On CT scanning, a significant …

Synchronous Tri-Cavitary Biphasic Malignant Mesothelioma In A Dog Presenting With Dyspnea, Nawarus Prapaiwan, Tawewan Issarankura Na Ayudhaya, Poonavit Pichayapaiboon, Onrampha Tanglakmankhong

The Thai Journal of Veterinary Medicine

Malignant mesothelioma is an uncommon tumor that has a challenging diagnosis and a tendency for late diagnosis. A 7-year-old intact male dog presented with respiratory distress. Thoracic radiography revealed pleural effusion and bone reactions at multiple ribs. A computerized tomography scan with rib biopsy was suggested as a diagnosis plan. Unfortunately, the dog died. Gross pathological findings demonstrated multifocal to coalescing, pinkish-white firm masses scattered over the parietal pleural surface, extended to the serosa of the diaphragm and the pericardium, making them adhere to each other and causing the coalescence of a white irregular mass at the diaphragm. Multiple white …

Long-Term Tapering Regimen Use Of Oclacitinib For The Control Of Pruritus In An Atopic Dog, Piyarat Chansiripornchai

The Thai Journal of Veterinary Medicine

Abstract

Canine atopic dermatitis (CAD) is a genetically predisposed inflammatory skin disease with a global distribution, yet it is incurable. A key clinical sign of CAD is pruritus. Oclacitinib has proven effective in managing pruritus in atopic dogs. This case report details the long-term administration of oclacitinib every other day for controlling pruritus in an atopic dog. An 8-year-old atopic Bangkaew dog presented with pruritus, alopecia, and recurrent Malassezia pachydermatis infection. To control the pruritus, the dog received oclacitinib at a dose of 0.4 mg/kg orally every 24 hours for 30 weeks. The pruritus visual analog scale (PVAS) decreased from …

Fatal Disseminated Toxoplasmosis In Captive Red Kangaroo (Macropus Rufus) And Parma Wallaby (Macropus Parma): Pathological And Immunohistochemical Investigations, Sawang Kesdangsakonwut

The Thai Journal of Veterinary Medicine

Abstract

Toxoplasmosis is a protozoan zoonosis caused by Toxoplasma gondii. Marsupials are considered a susceptible intermediate host. T. gondii is mainly transmitted to intermediate hosts via the fecal-oral route. A captive red kangaroo was diagnosed with disseminated toxoplasmosis based on clinicopathological and immunohistochemical (IHC) investigations. Two years later, a five-year-old Parma wallaby was kept in the same area as the red kangaroo and showed clinical signs of depression, withdrawal from the troop, and weakness. The wallaby died within two days after showing the clinical signs. Pathological findings in this wallaby were compatible with disseminated toxoplasmosis. Tachyzoites and tissue cysts …

Effects Of Extracellular Vesicle Transfer On The Immunological Acceptance Of The Fetal Allograft, Heloisa Moreno Rutigliano

Funded Research Records

No abstract provided.

Novel Hamster Models Of Chikungunya Viral Arthritis, Tian Wang, Zhongde Wang

Funded Research Records

No abstract provided.

Determining The Interrelationships For Dietary Intake Of Lipid Oxidation Products From Thermally Abused Oils, The Gut Microbiome, And Gut Health, Abby Benninghoff

Funded Research Records

No abstract provided.

Lingual Histiocytic Sarcoma In A Dog: A Case Report, Seulgi Bae

The Thai Journal of Veterinary Medicine

An 8-year-old spayed Maltese dog was presented for the evaluation of a lingual mass. The dog had excessive drooling and dysphagia. Oral examination revealed a soft, fluctuating mass at the left side of the tongue. Computed tomography showed a 21 × 32 × 66 mm lingual mass and enlarged left medial retropharyngeal lymph node. On cytology of the lingual mass, a round cell tumor was suspected; however, it was not responsive to glucocorticoid therapy. Because of severe complications, glossectomy and lymphadenectomy were performed; unfortunately, the patient died because of dyspnea in the postoperative period. Histopathologic examination and immunohistochemistry revealed lingual …

Curcumin Alleviates Inflammatory Effects Of Ketamine Anesthesia In Postnatal Rats, Soroush Afshar Ghahremani, Abbas Raisi, Sohrab Minaei Beirami, Houman Kahroba, Mahnaz Mardani, Omid Dezfoulian, Vahideh Tarhriz

School of Graduate Studies Faculty Publications

Curcumin has been employed in traditional medicine for over a millennium to treat various ailments, and its global use is now widespread. Chinese medicine relies heavily on curcumin as a primary element and uses it to cure infectious diseases, skin disorders, depression, and stress. It has cardioprotective, neuroprotective, and anti-diabetic properties, as well as pharmacological effects on disorders like type II diabetes, atherosclerosis, and human immunodeficiency virus replication. The anti-cancer activity of curcumin has been studied extensively with notable improvements in gastrointestinal, melanoma, urogenital, breast, and lung malignancies. We investigated the anti-inflammatory effects of curcumin on expression of tumor necrosis …

Surgical Treatment Of Intra-Abdominal Vaginal Cyst Severely Adhered To Associated Organs In A Dog, Nithida Boonwittaya, Anchisa Suvisit, Piraya Jaiyangyeun, Wallaya Phongphaew, Kasamapohn Hutachinda

The Thai Journal of Veterinary Medicine

A twelve-year-old female Shih Tzu was presented for investigation and treatment of a vaginal mass. Partial resection, intracavitary fluid drainage and mucosal lining curettage had been made in the previous laparotomy. Computed tomography (CT) and perioperative gross appearance revealed a large vaginal cyst extended into the pelvic canal that was adhering to the bladder trigone, both ureters, the urethra and the descending colon. The mass was resected completely. The dog recovered uneventfully. To the author’s knowledge, this is the first report of a canine intra-abdominal vaginal mass that was preoperatively evaluated using CT and the histological result was most consistent …

Treatment Strategies Of Biliary Stones Through Multiple Liver Lobectomy And Cholecystectomy In A Dog, Jae-Hwan Jung, Seoung-Yob Ahn, Mu-Young Kim, Hun-Young Yoon

The Thai Journal of Veterinary Medicine

A 12-year-old spayed female Maltese dog weighing 3 kg was referred to our Veterinary Medical Teaching Hospital for the evaluation of gallstones. The dog had a history of splenectomy and underlying Cushing’s syndrome and had received ursodeoxycholic acid for 2 months. The dog presented with clinical symptoms, including icterus, vomiting, anorexia, lethargy, and abdominal pain. Radiography, ultrasonography, and computed tomography revealed choleliths in the gallbladder, cystic duct, common bile duct, and the hepatic ducts of the quadrate, left medial, and left lateral lobes. In addition, we identified atrophy and cirrhosis of the corresponding lobes of the liver. The choleliths were …

Prediction Of Ehrlichia Canis And Babesia Canis In Canine Blood Sample By Mindray Bc-5000 Vet Hematology Analyzer, Sorawat Thongsahuan, Hansuk Buncherd, Supinya Thanapongpichat, Sataporn Noosong, Siriyaporn Choobunsong, Kanitta Srinoun

The Thai Journal of Veterinary Medicine

Tick-borne diseases caused by the Babesia canis (B. canis) and Ehrlichia canis (E. canis), have been increasing recently in clinical veterinary. In veterinary clinics, complete blood counts (CBCs) are commonly analyzed using automated flow cytometric analyzers like the Mindray BC-5000 Vet hematology analyzer. In this study, the predictive significance of the diagnostic blood parasites B. canis and E. canis obtained from hematological parameter were measured. Red blood cell (RBC) and platelet parameters firstly discriminated the canine blood parasites infection from those healthy dogs. The diagnostic performance of absolute number of monocytes between B. canis and E. …

Monorchidism With Ipsilateral Renal Agenesis In A Cat, Jinyoung Choi, Sungin Lee

The Thai Journal of Veterinary Medicine

A 1-year-old intact male ragdoll weighing 5.9 kg was presented for general wellness examination and castration. Upon physical examination, neither testes could be palpated in the scrotum. Blood test results (complete blood cell count, serum biochemistry and electrolyte analysis) showed no remarkable findings. Radiographic and ultrasound examination did not detect the right kidney and testis in the abdominal cavity. However, we were unable to visualize the right kidney and testis in the abdominal cavity. An exploratory laparotomy for cryptorchidism revealed that although the left testis was intact, there was no right kidney, ureter and ipsilateral testis in the abdominal cavity. …

Necrotic Lung Tumor Mimicking Primary Pulmonary Abscess On Computed Tomographic Imaging Study In A Dyspneic Dog, Mihyun Choi, Namsoon Lee

The Thai Journal of Veterinary Medicine

A 14-year-old spayed female Shih-Tzu dog was evaluated for a 1-month history of progressive coughing. Results of the complete blood count and serum biochemistry panel indicated inflammation. Thoracic radiography showed pleural effusion, and cytology revealed septic pyothorax. After antibiotics medication, the patient improved clinical signs but relapsed pleural effusion with a suspicious lung lesion. Computed tomography (CT) of the thorax showed a cavitary lesion with ring-enhanced irregular walls and poorly defined margins in the left cranial lung lobe. The main differential diagnosis considered was lung abscess, but the histopathological diagnosis was necrotic lung adenocarcinoma. This case suggests that both a …

Global Prevalence And Zoonotic Potential Of Cryptosporidiosis In Camels (Camelus Dromedarius): Systematic Meta-Analysis, Mohamed Marzok, Hussein Babiker, Mohamed Tharwat, Sabry El-Khodery

The Thai Journal of Veterinary Medicine

In this study, meta-analysis on prevalence and zoonotic significance of cryptosporidium infection in camels was performed. This study was completed following the instructions of PRISMA. Data were extracted afterward a complete search, and eligible articles were identified. The data were analyzed using a specific software program for meta-analysis, and the results included effect size, confidence intervals (CI), heterogeneity, and publication bias. A total of 4075 camels from 18 accepted studies were investigated for cryptosporidium infection. Of all, 287 camels were found positive for cryptosporidium infection, with a prevalence of 7.04%. The prevalence of cryptosporidiosis in camels varied significantly among …

Bovine Respiratory Syncytial Virus: First Identification In Eastern Algeria Based On Direct Immunofluorescence And Elisa Tests, Imene Abdelmalek, Bakir Mamache, Amine Boudaoud, Yacine Khanfri

The Thai Journal of Veterinary Medicine

Bovine respiratory syncytial virus (BRSV) is the main agent of the bovine respiratory disease complex (BRD). Its circulation among the Algerian bovine population has been strongly suspected but never confirmed. This study investigated the prevalence of BRSV in cattle in eastern Algeria. From 2022 to 2023, a total of 225 serum and 102 lung tissue samples were collected from farms and slaughtered cattle of different ages. Samples were tested for BRSV antibodies by Enzyme-Linked Immunosorbent Assay (ELISA) and BRSV antigens by Direct Immunofluorescence Test (DFAT). Histopathological examination was also performed on lung tissue sections. BRSV-specific antibodies were detected in 91.11% …

Presynchronization In Sheep Ensures Synchronization Of Next Estrus And Improves Fertility, Bülent Bülbül, Mehmet Köse, Mesut Kırbaş, Kenan Çoyan, Mehmet B. Ataman, Emine A. Bekçi, Seyit Ümütlü, Uğur Demirci, Bumin E. Teke

The Thai Journal of Veterinary Medicine

In this study, fertility was evaluated either in the first hormonally synchronized or in the subsequent natural estrus among 202 sheep during the breeding season. Intramuscular (im) PGF2α was administered 11 days apart in both the PG (n=50) and Pre-PG (n=50) groups, while im PGF2α was given at the removal of an intravaginal progesterone sponge (after 11 days) in the Sponge (n=51) and Pre-Sponge (n=51) groups. Estrus was monitored following the last hormonal application (day 0) in all groups and starting from day 16 in the Pre-PG and Pre-Sponge groups for 5 days. Ewes were mated during the first hormonally …

Development Of A Silicone-Based Goat Uterine Model For Artificial Insemination Training, Sakdichod Kimsakulvech

The Thai Journal of Veterinary Medicine

A goat uterine model for artificial insemination (AI) training has not been created previously. The eight goat uteri were collected from the slaughterhouse and measured to serve as a prototype size for the model. A goat uterine model was developed based on silicone material. This study compared the suitability of silicone between 20,000 and 30,000 centipoise viscosity and the cervical opening between the circular and linear types for this model. These were made up of four models with alternating differences between viscosity and cervical openings. Twenty AI officers evaluated the satisfaction score of the internal and external appearance of the …

Exploring Breed-Related Patterns And Diagnostic Factors In Canine Hypothyroidism: Unveiling Novel Paradigms, Narinthip Buckland, Chalermpol Lekcharoensuk, Monchanok Vijarnsorn, Smith Pongcharoenwanit, Natpreeya Premjaroen, Thanachote Tangporntawee, Narudee Kashemsant

The Thai Journal of Veterinary Medicine

Canine primary hypothyroidism is one of the most common endocrinopathy diseases in dogs affecting various body systems. In veterinary practice, the measurement of total thyroxine together with canine thyroid-stimulating hormone (TSH) was suggested to have high accuracy for diagnosing this disease. However, the changes in these recommended diagnostic parameters can be distinguished only in a hypothyroid dog with progressive deterioration or later in the disease. This study investigated the relevant predicting factors of canine primary hypothyroidism from animal characteristics and blood chemistry. Among the 672 dogs that met the inclusion criteria, 77 dogs had hypothyroidism and 179 had non-hypothyroidism. Age …

Bioinformatics Analysis And Comparison Of The S Protein Of Canine Coronavirus And Feline Coronavirus, Bo Dong, Xiaowei Zhong, Jiaqi Zhuo, Renyi Hu, Xiaodong Zhang, Xiaolian Xu, Haiyan Deng, Xiaofang Yan, Weiming Lin

The Thai Journal of Veterinary Medicine

The Coronavirus S protein induces neutralizing antibodies, specific receptor binding, and membrane fusion between the virus and host cells. These changes are crucial to understanding the mechanism, genetic correlates, and prophylactic treatment of viral infection. In this study, the spike (S) protein structure and phylogenetic association of CCoV and FcoV were analyzed using bioinformatics. The results showed that the S proteins of CCoV and FCoV contained transmembrane regions and signal peptides. The S proteins of these coronaviruses were soluble. The S proteins of these strains also contained two functional domains and two motifs, i.e., corona_S1 and corona_S2. Phylogenetic analysis showed …

Comparison Between Surgical And Non-Surgical Treatments Of Concomitant Cranial Cruciate Ligament Rupture And Medial Patellar Luxation In Small-Breed Dogs, Ekkapol Akaraphutiporn, Chalika Wangdee, Irin Kwananocha

The Thai Journal of Veterinary Medicine

Cranial cruciate ligament rupture (CrCLR) and medial patellar luxation (MPL) are common problems that cause hindlimb dysfunction, lameness and pain in dogs. Although surgical intervention is recommended for these conditions, it may not be suitable for an individual with some underlying diseases. The objective of the present study was to compare the outcomes between surgical and non-surgical treatments for concomitant CrCLR and MPL in small-breed dogs. Seven stifles from five small-breed dogs with concomitant CrCLR and MPL were enrolled and divided into two groups. Four limbs (three dogs) in Group 1 were treated conservatively, and three limbs (two dogs) in …

Development Of A Preliminary Clinical Approach For Detecting Insulin Resistance For Normoglycemic Control In Canine Diabetes, Chutirat Torsahakul

The Thai Journal of Veterinary Medicine

Consistent and effective blood glucose (BG) control is crucial in the treatment of diabetes mellitus (DM) and insulin resistance (IR). In this study, the surrogate indices for monitoring insulin sensitivity and the preliminary clinical approach for detecting IR were established. Fasting serum C-peptide was measured by a commercial enzyme-linked immunosorbent assay (ELISA) kit and utilized as an endogenous insulin representation. The homeostasis model assessment of insulin resistance (HOMA-IR) was then calculated. To detect the IR, the relationship between HOMA-IR and fasting serum C-peptide in each individual subject was analyzed, and designed cut-off values. The results revealed that the HOMA-IR of …

Progestin-Based Non-Surgical Contraception In Dogs And Cats: A National Survey Of Practices Among Thai Veterinarians, Shanaporn Leelakajornkit, Piyaporn Kamdee, Suppawiwat Ponglowhapan

The Thai Journal of Veterinary Medicine

This cross-sectional study aimed to assess the current use of progestins as contraceptives in dogs and cats and to evaluate veterinarians' awareness of related complications across Thailand. A total of 724 veterinarians participated, predominantly female (66.3%) and aged 31-40 years (49.6%), with most working in Bangkok and its metropolitan area (52.6%) and having 6-15 years of experience in small animal practice (46.4%). Approximately 6.8% of respondents (49/724) reported using injectable progestins, mainly in female dogs (87.8%) and cats (83.7%), but also in male dogs (18.4%) and cats (14.3%). Veterinarians using progestins were mostly male (59.2%), with an average age of …

Effect Of Modified Smart Extender On Sperm Longevity And Frozen-Thawed Semen Quality In Bantam Chicken (Gallus Gallus), Nattaporn Chaysakul, Naruephon Leeamnuaycharoen, Marvin Bryan Salinas, Teepakorn Lertwichaikul, Chakorn Kunkaew, Jureerat Sumretprasong, Anucha Sathanawongs

The Thai Journal of Veterinary Medicine

The round body shape and short legs of Bantam chickens (Gallus gallus) pose breeding challenges, making artificial insemination critical for these animals. To contribute to such assisted reproductive technology in avians, this study assessed the effect of a modified simple medium for assisted reproductive technology (SMART) extender on sperm longevity and frozen-thawed semen quality compared to the Blumberger Hahnen Sperma Verdünner (BHSV) extender. Sperm motility and viability were measured in 20 roosters at fresh and chilled conditions at 4-, 24-, and 48-hour intervals. For the subsequent freezing step, 6% and 9% DMA were added to both extenders as …

Morphological And Morphometric Variations Of The Tympanic Bulla Between Domestic Shorthair And Brachycephalic Cats Utilizing Computed Tomography, Naparee Srisowanna, Damri Darawiroj, Nan Choisunirachon, Chutimon Thanaboonnipat, Sirinun Pisamai Tabtieang

The Thai Journal of Veterinary Medicine

Tympanic morphology of the dogs was reported to be varied due to the characteristics of the skull types. The small tympanic bulla is normally seen in brachycephalic dogs. However, this variation in narrowed-skull shaped cats has not been unveiled yet. The objective of this study was to describe the tympanic morphology of cats between brachycephalic and domestic shorthair (DSH) cats. Computer tomography (CT)-skull images of 15 domestic shorthair cats and 11 brachycephalic cats were evaluated for tympanic dimension on transverse and dorsal planes and the tympanic bone thickness. All parameters were compared between both groups. The results revealed that all …

Research Progress On The Structure And Function Of The Main Glycoproteins Of Bovine Infectious Rhinotracheitis Virus, Xin Zhang, Ruizhen Jian, Weijuan Jia, Yunjiao Chen, Qinglei Meng, Fang Yang, Jianjian Han, Zhilin Liu, Zelin Jia, Jiayu Cui, Xueli Wang

The Thai Journal of Veterinary Medicine

Infectious bovine rhinotracheitis (IBR) is an acute, febrile, and contact infectious disease. Bovine infectious rhinotracheitis is endemic in China and even the world, which not only restricts the development of the cattle industry but also brings significant economic losses to farms. Infectious bovine rhinotracheitis virus (IBRV) contains 25 - 33 structural proteins, of which glycoproteins gB, gC, gD, gE, gG, gH, gI, gK, gL, and gM are the major structural glycoproteins of bovine rhinotracheitis virus, and all of these glycoproteins are interconnected with the assembly, invasion, release, and replication of the virus, and the only glycoproteins that are known …

A Systematic Literature Review Of Granulocytes-Colony Stimulating Factor Treatment In Animals, Syahirah Ahmad Affandi, Nurul Hayah Khairuddin, Mohammed Sadiq Babatunde, Azalea Hani Othman, Collin Looi Seng Kim, Siti Sarah Othman, Sharifah Roohi Syed Waseem Ahmad

The Thai Journal of Veterinary Medicine

This study presents a systematic literature review (SLR) on the efficacy of granulocytes-colony stimulating factor (G-CSF) as a treatment component in relation to clinicopathological parameters and overall outcomes. Using the PICO approach, a research question development tool, the SLR was designed to identify the animals in which G-CSF had been used, the types of G-CSF utilized and their effectiveness as a therapeutic agent in stimulating haematological parameters, as well as their potential adverse effects. Three primary keywords associated with the review topic were selected and incorporated into the search query to retrieve pertinent literature from three databases: Scopus, Science Direct, …

Outcomes In Dogs Undergoing Surgical Correction For Septic Peritonitis: A Retrospective Study In 61 Cases (2019-2022), Krishaporn Kradangnga, Naipaporn Kongrattanachat, Wichulada Suwansukroj, Jiraporn Supasombatolan, Chayanon Tiaraksa

The Thai Journal of Veterinary Medicine

This retrospective study described clinical parameters, evaluated the chance of death (hazard ratio) and compared outcomes until hospital discharge in septic peritonitis dogs that underwent surgery in 61 cases at a single academic referral hospital population. The surgical records of 223 dogs with suspected septic peritonitis requiring surgical intervention were reviewed and a total of 61 dogs, primarily mixed breed (34.43%), with intraoperative gross lesions and cytology confirmed septic peritonitis were included in the study. The gastrointestinal tract was the most common source of septic peritonitis (52.46%). The overall survival to hospital discharge was 52.46%. Admission time until surgery, drain …

Ultrasonic Doppler As A Guide For Feline Peripheral Arterial Catheterization, Satoshi Haginoya, Elizabeth J. Thomovsky, Hsin-Yi Weng, Paula A. Johnson, Aimee C. Brooks

Purdue University Libraries Open Access Publishing Fund

Objectives

The study aimed to determine if an ultrasonic Doppler-guided technique (UDGT) leads to improved placement efficacy (time, success) of feline dorsal pedal arterial catheters vs the traditional palpation-guided technique (TPT).

Methods

A total of 26 adult, client-owned cats requiring sedation or general anesthesia for any reason, aged >12 months and weighing >3.0 kg, and with Doppler blood pressure measurements of at least 80 mmHg were enrolled. Each hindlimb was randomly assigned for dorsal pedal arterial catheterization using either the UDGT or TPT. With the UDGT, the location of the artery was identified by an audible sound using the Doppler. …