Biology Commons^™

Substrate Complexity Is Not Correlated With Skin Pattern Complexity In Callistoctopus Furvus, Emily Lekas

Honors Theses

Callistoctopus furvus is an understudied, nocturnal octopus that inhabits shallow, subtropical waters in the western Atlantic. This species relies on camouflage to blend in to diverse environments to escape predators. To understand the relationship between substrate and skin patterning in this species, we used second-by-second analysis of video data recorded in the field. We compared frequencies of four substrate types (sand, rock, algae, and seagrass) ranked by contrast across ten skin patterns displayed by C. furvus. Chi-squared analyses showed significant results that the four substrates were unevenly represented in every skin pattern. However, the data did not support our hypothesis …

Impact Of Temperature And Microbial Infection On The Honey Bee Hemocytes, Michael E. Oeth

Master's Theses

Introduction

Honey bees (Apis mellifera) rely on hemocytes for immunity, wound healing, and hemolymph homeostasis. While 32°C reflects optimal hive conditions, suboptimal temperatures (22°C) and stressors like pathogens (Varroa destructor, bacteria) or pesticides impair hemocyte function. Using clodronate liposomes (CLD) to deplete hemocytes, we assessed how immune suppression interacts with these stressors.

Methods

Newly emerged (5-day-old) and older (15-day-old) bees were assigned to: CLD, control liposomes (LP), PBS, injection wound, or no treatment. Cohorts were exposed to 32°C (optimal) or 22°C (stressful for non-immunosuppressed bees). Fifteen-day-old bees were challenged with Escherichia coli or Staphylococcus aureus. Survival, hemolymph volume, and hemocyte …

Antimicrobial Peptides Improve Antibiotic-Mediating Killing Of Methicillin-Resistant Staphylococcus Aureus (Mrsa) Biofilms, Alya R. Theriault

All Theses And Dissertations

Staphylococcus aureus can cause drug-resistant, biofilm-associated infections. These infections place methicillin-resistant S. aureus (MRSA) as one of the sixth leading bacterial pathogens associated with deaths due to antimicrobial resistance. Traditional antibiotics are no longer enough to treat these resistant infections and novel therapeutics are needed. Antimicrobial adjuvants are a potential strategy for improving efficacy of existing antibiotics, and antimicrobial peptides (AMPs) may have adjuvant activity. Recent reports showed that AMPs improve antibiotic activity against planktonic staphylococci, but whether AMPs might alter antibiotic efficacy against biofilm-resident staphylococcus is less clear. We tested the effect of nine AMPs on staphylococcal biofilm susceptibility …

A Cross-Taxa Comparison Of Avian Telomere Dynamics, Age, And Lifespan, Benjamin Konigsberg

Honors Theses

When eukaryotes replicate cells throughout their life, the end regions of chromosomes naturally degrade as a result of the 5' to 3' directionality of DNA polymerase. There is a point when the chromosome is too damaged to provide normal cellular functions, so the cell will die. Telomeres act as a buffer by providing repetitive sequences of non-coding nucleotides. While telomeres do shorten during replication events, the enzyme telomerase can extend telomeres to prevent senescence. Telomere lengths vary between individuals based on different stressor and stress mitigation. Telomeric rate of change is a metric that can capture telomerase activity by measuring …

Quantification Of Blue Carbon Within The Marine Animal Forest On The Rio Grande Valley Artificial Reef, Michelle Kathryn King

Theses and Dissertations

The protection and enhancement of coastal ecosystems provides a number of benefits such as heightened biodiversity, increased fisheries, and enhanced carbon capture (Yeemin et al., 2024). The study of blue carbon ecosystems has expanded rapidly in the last two decades since the term was coined in 2009 (Lovelock & Duarte, 2019). The most well-known blue carbon ecosystems include vegetation-dominated ecosystems such as seagrass meadows, salt marshes, and mangrove forests (Howard et. al., 2014). Prior studies have overlooked Marine Animal Forests (MAF) ability to capture carbon, until recent studies on soft coral (Coppari et al., 2019) and sponge (Rix et al., …

Pastoral Land Condition: Kimberley Land Condition Standards, Robert Sudmeyer, Rick Fletcher, Kathryn Ryan, Matthew Fletcher, Charles Martin, Philip Thomas, Karen Holmes, Karyn Reeves, Wayne Fletcher

Natural resources published reports

This report outlines the conceptual basis and quantitative land condition standards that define acceptable pastoral land condition for the Kimberley, Western Australia (WA), to meet the regulatory requirements of the Land Administration Act 1997 and the Soil and Land Conservation Act 1945.

The Department of Primary Industries and Regional Development (DPIRD) develops regional-level pastoral land condition standards for WA to implement the Framework for sustainable pastoral management – Revised edition, which is designed to address the Office of the Auditor General’s recommendations to improve the management of pastoral lands in WA. The application of these standards is expected to …

The Effect Of Calorie Restriction On Humoral Responses Towards The Influenza Vaccine, Grayson Kobluk

Celebrating Scholarship and Creativity Day (2018-)

Calorie restriction (CR) - a reduction in caloric intake without malnutrition - has been widely studied for its impact on lifespan and the onset of age-related diseases. Emerging research indicates that CR also influences immune function, though its effects can vary depending on the degree of restriction, duration, and individual characteristics. This study examined how CR effects vaccine-specific antibody responses following influenza vaccination. Male and female mice were maintained on either a control diet or a calorie-restricted diet and vaccinated with an inactivated influenza virus vaccine. Antibody titers were measured 28 days post-vaccination to evaluate the magnitude of the humoral …

Life In Plastic? Not So Fantastic: Marine Plastic Pollution On San Salvador Island, Dayna Wiley

Celebrating Scholarship and Creativity Day (2018-)

Marine plastic pollution, also known as marine macroplastic debris (MMD), impacts many aspects of marine ecosystems. MMD is defined as macroplastic (> 5mm) objects that are deposited in the ocean and are found floating in the water column or washed up on beaches. MMD washup is significantly affected by ocean and wind currents. The Antilles Oceanic Current and the Trade Winds move west across the Atlantic Ocean, and thus were predicted to cause more MMD deposition on the eastern side of San Salvador Island, Bahamas. Beaches on the North (Graham’s Harbor), South (French Bay), East (East Beach), and West (Columbus …

Exercise Physiological Insights Into Exercise-Induced Muscle Cramping: Blood Lactate And Creatine Kinase As Biomarkers In College Students, William Yu

Celebrating Scholarship and Creativity Day (2018-)

Creatine kinase (CK) is an enzyme that's found in the skeletal muscle, heart muscle and brain. When any of these tissues are damaged, they leak creatine kinase into your bloodstream. Elevated CK levels may indicate muscle injuries, cramping, or disease1. There are different types of CK, which are also known as isozymes for the cytoplasm, CK-MM, CK-MB, and CK-BB. CK-MM focuses on musculoskeletal, CK-MB focuses on heart muscles, and CK-BB focuses on the brain tissue. There are also two isozymes in the mitochondria15. Cramping is common problem amongst runners and can be described as “painful, spasmodic contraction of the skeletal …

The Effects Of Climate Change On The Spread Of Mosquito-Borne Diseases, Lauren Provoncha, Sarah Franta, Portia Lawrence

Celebrating Scholarship and Creativity Day (2018-)

This paper examines the impact of climate change on the spread of mosquito-borne diseases, focusing on how rising temperatures, altered precipitation patterns, and extreme weather events influence mosquito habitats and disease transmission. It explores the ecological and public health implications of these shifts and highlights the importance of understanding climate-disease dynamics to inform effective prevention and intervention strategies.

Ecological Consequences Of Variable Glacial Melting On Arctic Biodiversity: Trophic Shifts And Community Dynamics, Aislyn Malone, Audrey Swart

Celebrating Scholarship and Creativity Day (2018-)

Our project investigated the profound impacts of increasing glacial melting on various trophic levels, habitats, and other ecological processes.

Seasonal And Temporal Influences On Successful Crossing Rates By Ungulates Of A North Utah Wildlife Overpass, Blake Ledbetter

All Graduate Theses and Dissertations, Fall 2023 to Present

Encroachment of human infrastructure fragments wild landscapes and introduces a suite of negative impacts for humans and wildlife. In Utah, roadways threaten migratory ungulates by creating a barrier to movements and preventing access to seasonal migration routes. To mitigate these conflicts, state transportation agencies often install wildlife crossing structures to allow animals to safely cross over or under roadways. Selecting the proper crossing structure requires consideration of the species of interest, landscape, location, and structural dimensions. Often there is balance between the optimal location, the dimensions of the crossing structures, and what is feasible given the landscape. In 2018, the …

Culturing And Characterization Of Arbuscular Mycorrhizal Fungi Native To The Sagebrush Steppe, Jacob Venable

Boise State University Theses and Dissertations

Arbuscular mycorrhizal fungi (AMF) are obligate biotrophs that form symbiotic associations with the roots of over 70% of terrestrial plants. These symbioses are crucial in plant nutrient acquisition, stress tolerance, and soil health. AMF inoculum could be valuable for ecological restoration, but challenges in culturing and multiplying AMF limit their use in natural habitats. In this project, I investigated methods to characterize and culture AMF native to the sagebrush steppe. For comparison, I also grew a non-native strain of the AMF fungus Rhizophagus clarus. First, I used trap cultures to multiply AMF present in roots and field soil collected …

Dental Microwear Of Miocene Primates From The Carpathian Basin, Rudabánya, Hungary, Anna K. Wilcox

Biological Sciences Undergraduate Honors Theses

This study reconstructs and compares the dietary habits of the late Miocene primates Anapithecus hernyaki and Rudapithecus hungaricus by analyzing dental microwear patterns on fossilized teeth recovered from Rudabánya, Hungary. Previous research suggested that these sympatric species were both primarily frugivores but were unable to separate them by diet. However, earlier studies were limited by smaller sample sizes and less advanced methodologies. This study used an expanded sample and modern microwear texture analysis techniques to compare molar and incisor microwear patterns between the two species. Results revealed that Rudapithecus molars exhibited higher complexity compared to Anapithecus molar complexity, suggesting a …

Assessment Of Nitrogen Source Utilization During Nitrogen Fixation And Nitrogenase Regulation By Methanosarcina Acetivorans, Avery Carter

Biological Sciences Undergraduate Honors Theses

Nitrogen is a crucial element in biomolecules such as proteins and DNA, essential for all cellular life. Biological nitrogen fixation, a process utilized by certain bacteria and archaea, reduces dinitrogen (N₂) to ammonia (NH₃), enabling growth in the absence of fixed nitrogen sources like NH₃. This process is driven by the metalloenzyme nitrogenase, which catalyzes the reaction: N₂ + 16ATP + 8e⁻ + 8H⁺ → 2NH₃ + H₂ + 16ADP + 16Pi. Due to its high energy demand, nitrogenase production and activity are tightly regulated. Among archaea, nitrogenase is found exclusively in methanogens, where its regulation remains poorly understood. We …

The Role Of Cis-Acting Super-Enhancer Long Noncoding Rnas In Triple Negative Breast Cancer Progression, Sakthi Muthukrishnan

Biological Sciences

Breast cancer encompasses a diverse range of diseases characterized by the uncontrolled proliferation of cells within the mammary gland. This condition results in an accumulation of a large number of genetic mutations within an individual, altering the complex internal signaling system of a cell. Millions of women are affected by breast cancer, which remains a significant threat despite medical advancements. Ductal carcinoma in situ (DCIS) acts as a precursor to invasive ductal carcinoma (IDC), however, not all cases progress to invasive cancer. Triple-negative breast cancer (TNBC) is identified to be one aggressive subtype of IDC, where the cells lack sufficient …

Non-Invasive Focused Ultrasound To Reduce Gut Inflammation In Parkinson’S Disease, Amal F. Siddiqui

Biological Sciences

Parkinson's Disease (PD) is a neurodegenerative motor disorder that affects millions of people worldwide, with projections suggesting the number of diagnosed cases could reach 15 million by 2040 (Dorsey et al., 2018). While PD is primarily recognized for its impact on movement, it also frequently causes non-motor symptoms, including gastrointestinal (GI) issues such as constipation, which affects 60-80% of patients. Chronic gut inflammation has been proposed as a key factor exacerbating these symptoms. Despite the prevalence of GI complications in PD, they are often overlooked, and existing treatments for constipation are limited in both efficacy and scope. Vagus Nerve Stimulation …

Stimulus Dependence Of Visually Guided Behavior In Drosophila Melanogaster, Jessica Osarenoma Airhienbuwa

Biological Sciences

Vision is very important for navigating the world around us. The fruit fly, Drosophila melanogaster, is a great model for studying how the brain controls visually guided behavior. This is because they have a small nervous system, good genetic tools, and a complete map of their brain connections. In fruit flies, visual projection neurons (VPNs) send information from the eyes to the central brain, which affects what they see and how they act. This research looks at how certain groups of nerve cells influence fruit flies' behavior based on what visual stimuli. To study the brain circuits behind these behaviors, …

Screening Modified Polycyclic Compounds In Myotonic Dystrophy Type 1 Cell Lines, Maria Villacreses Valarezo

Biological Sciences

Myotonic dystrophy type 1 (DM1) is an autosomal dominant neuromuscular disease with no treatment options and causes progressive muscular atrophy and weakness. DM1 occurs when the DMPK gene contains an abnormal CTG repeat expansion in the 3’ untranslated region. Transcription of the expansion leads to sequestration of RNA binding proteins and downstream splicing dysregulation. This dysregulation ultimately affects many systems in the body leading to the DM1 phenotype. This project consists of two parts, with one of our goals being to test experimental small molecule (MPC-04) in an immortalized patient-derived DM1 cell model. Using RNA sequencing data from patient-derived DM1 …

Genomic Diversity Of Salmonella Enterica Serotype Braenderup In New York State, Nicole Zac Soligno

Biological Sciences

The Gram-negative Salmonella enterica (family Enterobacteriaceae) is a common foodborne pathogen mainly isolated from foods of animal origin. Salmonella can be transmitted to humans, causing diverse symptoms, from self-limiting gastrointestinal diseases to more fatal typhoid fever. The young, elderly, and Individuals with weakened immune systems are especially at risk from salmonellosis. Salmonella is a concern to public health and the food industry throughout the world, and its severity depends largely on its serotype, a classification based on the unique combination of surface antigens. In this study, I aimed to elucidate the population structure and antimicrobial resistance determinants of S. enterica …

Coaggregation With Actinomyces Naeslundii Reduces Corynebacterium Matruchotii Cell Division Rate And Increases In Cell Length, Sarah M. Kenny

Biological Sciences

Corynebacterium matruchotii is believed to form a scaffold-like structure within the human oral cavity so that other species of bacteria have a place to bind. Many types of bacteria may be found within oral biofilms, commonly referred to as dental plaque. Actinomyces naeslundii are associated with dental caries and they are frequently found in dental plaques. Previous studies in our lab have demonstrated that A. naeslundii has a greater coaggregation rate with C. matruchotii than other Actinomyces species. The purpose of this study is to determine the effect of coaggregation with A. naeslundii on C. matruchotii growth kinetics. In this …

A Comparative Study Of Urban And Natural Nesting Gray Hawks In The Lower Rio Grande Valley Of South Texas, Evan Farese

Theses and Dissertations

Urbanization can negatively impact birds of prey, which occupy higher trophic levels. The Gray Hawk (Buteo plagiatus) is a neotropical raptor inhabiting the Lower Rio Grande Valley (LRGV) of Texas, where it is threatened. The species’ ecology has been little studied and it is unclear how urbanization may affect population viability. I studied Gray Hawk reproductive success, diet, and thermal ecology at nests in urban and natural habitats in the LRGV. Camera trap data showed adults at urban nests delivered mostly avian prey, while mammalian prey was most frequently brought to natural nests. Data from temperature loggers showed …

The Role Of Ucp2 In Pancreatic Cancer Metabolism And Its Potential As A Radiosensitizer, Emily Rieff

Dissertations and Theses (Open Access)

Uncoupling protein 2 (UCP2) is a mitochondrial protein that regulates the flow of protons down the gradient established by the electron transport chain (ETC) without generating ATP, thus uncoupling the proton gradient from ATP generation. In tumors, specifically pancreatic cancer (PDAC), the ETC is highly stimulated to generate the copious ATP needed by the tumor to grow. However, extended ETC use increases reactive oxygen species (ROS), and if left unchecked, results in cell death. To evade this, PDAC employs antioxidant strategies, including upregulating UCP2 in tumor cells. In addition to its uncoupling function, UCP2 indirectly controls ROS levels by maintaining …

Assessing Phenotypic Variation Across Generations Of Iberodes Littoralis Under Climate Change, Mariangel M. Fernandez Silva

Electronic Theses, Projects, and Dissertations

The consequences of climate change and anthropogenic activity have decreased wildlife biodiversity. Plants are particularly vulnerable to climate change due to their large biomass on the planet and sessile nature. A particularly useful method for plants to cope with environmental changes is phenotypic plasticity. Adjusting morphological traits through plasticity can help plants cope with environmental changes. Furthermore, plastic responses can be passed down through methods such as changes in DNA sequence or epigenetic modifications.

Our research project focuses on an herb, Iberodes littoralis, a species of concern native to the Siberian Peninsula with approximately thirteen extant populations. The data that …

Unraveling The Unknown: Characterization Of A Novel Antimicrobial Compound Found In Klebsiella Pneumoniae, Jasmal Cruz Perez

Electronic Theses and Dissertations

Klebsiella pneumoniae, a pathogenic bacterium resistant to numerous antimicrobials, is a worldwide health issue due to its ability to cause healthcare-associated diseases such as pneumonia and urinary tract infections. This study investigated an antimicrobial compound secreted by K. pneumoniae. The compound was found to possess inhibitory activity against Enterobacteriaceae members, including other Klebsiella pneumoniae strains, Citrobacter freundii, and Enterobacter cloacae. The inhibitory activity is mediated via a secreted protein that is active across a wide range of pH and temperature conditions. Higher concentrations of the compound enhanced antimicrobial activity. The antimicrobial protein suppressed biofilm formation during both …

The Impact Of Emdr Therapy On Past Suicidal Ideation: Lived Experiences Of Young Adults, Lindsey Faehnrich

Undergraduate Honors Theses

This study explores the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy in reducing suicidal ideation and improving mental health outcomes among college-attending young adults (ages 18–24) with a history of trauma. EMDR is a body-based psychotherapy designed to alleviate distressing thoughts and trauma. It gained attention for its positive impact on PTSD and has more recently been applied to other mental health disorders. The literature review highlights risk factors including trauma, mental health disorders, suicidal ideation, and EMDR. The methods detail a phenomenological approach, interviewing four young adults who underwent EMDR and experienced past suicidal ideation. This provided …

Whole-Genome Assembly And Annotation Of The Firecracker Penstemon (Penstemon Eatonii), David E. Jarvis, Mikel R. Stevens, Payton Carter, Ying Fei Lin, Kate E. Jaggi, Gabriela Jijon, Teal Kalt, Jouber Calixto, Samantha Standring, Kaitlin Torres, Kayla B. Stephensen, Hayley Mangelson, Noah H. Williams, Carolyn A. Wessinger, Peter J. Maughan, Paul B. Frandsen

Faculty Publications

The penstemons are ornamental annual flowering plants native to the Intermountain West and Rocky Mountains and commonly used for urban landscaping. Elite commercial penstemons are generally susceptible to abiotic stresses, including drought, root rot, cold, and high salinity. Firecracker penstemon (Penstemon eatonii), however, is much more tolerant to these stresses than most elite cultivars. Importantly, firecracker penstemon has been reported to hybridize with many other penstemons and therefore provides the opportunity to develop more tolerant elite cultivars through strategic crossing. To facilitate the study and utilization of firecracker penstemon, we sequenced and annotated the genome of a P. …

Unraveling Epigenetic Mechanisms That Regulate Breast Cancer Lung Metastatic Relapse By Rewiring The Immune Microenvironment, Jayanta Mondal

Dissertations and Theses (Open Access)

Metastasis accounts for >90% of cancer-related deaths and thwarting metastasis is widely considered to be the “Holy Grail” of cancer treatment. Breast cancer is the most common cause of cancer-related death among women and is characterized by its proclivity to spread to distant secondary organs like the lungs, and the brain. These disseminated tumor cells lie dormant at the secondary site and can undergo metastatic relapse. Epigenetic alterations are a predominant hallmark of cancer, however, its role in facilitating reawakening of dormant cancer cells and the subsequent metastatic relapse remains to be elucidated. To address this gap of knowledge, we …

Differential Progression Of Pancreatic Premalignancy In Geographically Distant Murine Transgenic Cohorts Uncovers Key Role Of Microbial Metabolites, Rian M. Howell

Dissertations and Theses (Open Access)

Cancer is a leading cause of death worldwide. Despite recent advances in diagnostic and therapeutic modalities, pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer that remains highly lethal. Efforts have been made to increase the understanding of the underlying mechanisms driving early stages of tumor development, when the cancer is most susceptible to intervention. To this end, genetically engineered mouse models (GEMMs) have been developed with the mutations most commonly seen in the patient population. Expression of these mutations in select cellular compartments has resulted in the ability to recapitulate characteristics of human pancreatic cancer such as the development of …

Physiological And Molecular Responses Of Diverse Rice Genotypes Under Drought Stress, Huda Mohmmed Alshaya

Graduate Theses and Dissertations

Climate change-induced drought stress is a significant constraint on global rice (Oryza sativa L.) production, threatening food security. This study evaluated the drought resilience of 15 diverse rice genotypes from the USDA mini-core collection under field, greenhouse, and osmotic stress conditions. Field trials assessed reproductive-stage drought tolerance based on panicle length (PL), number of spikelets per panicle (NSP), and spikelet sterility (SS). Greenhouse experiments examined moisture retention at the vegetative stage. Significant genotypic variation was observed, with genotypes 310724, 310779, 311181, 311603, 311793, and Vandana exhibiting drought tolerance through stable PL and SS. Additionally, genotypes 310100, 310428, 311255, N22, …