Biology Commons^™

Investigating Large Repeats In The Arabidopsis Thaliana Mitochondrial Genome Using Mitotalens, Megan Gusso

Honors Theses

This lab project explores the complexity of the mitochondrial genome by investigating large genomic repeats and their effect on flowering plants’ reproduction and viability. Mitochondria are the site of cellular respiration to create energy and contain their own DNA. This is counterintuitive because the byproducts of cellular respiration impose a threat of mutation for the stored DNA. The mitochondrial genome differs in size between animals and plants. Plant mitochondrial DNA is larger due to the presence of large, noncoding repeated sequences, and a large amount of DNA of unknown function. These sequences undergo high levels of recombination and rearrangement. The …

Denial Of Pregnancy Or Cryptic Pregnancy, Nadia N. Shuriah, Elaine Mcfarland, Bethany Spenn, Kaisha Butz Mcmanus

BIO4960: Practicum in Biology I

Denial of pregnancy, or cryptic pregnancy, presents a complex situation where individuals are unaware of their pregnancy until the late stages of labor. This study delves into the multifaceted nature of concealed and denied pregnancies, exploring their prevalence, factors contributing to them, and their implications for both individuals and healthcare systems. By reviewing relevant literature and case studies, we aim to illuminate the difficulties healthcare providers face in identifying and managing cases of denial of pregnancy. Additionally, we stress the significance of proactive screening and comprehensive care to ensure the well-being of mothers and infants. This research endeavors to deepen …

Exploring The Longitudinal Effects: Non-Traditional Pedagogies And Practical Learning On Biology Education And Medical Understanding, Thomas Ziebro

Honors Projects

Medical disinformation is becoming a rampant problem in the United States, and the Covid-19 pandemic highlighted it. There have been attempts to fight the problem at the source through fact verification. These attempts have been unsuccessful. This paper investigates the efficacy of non-traditional pedagogies and the correlation between them and an individual perceived and practical ability to understand their primary care provider. The purpose of this research was to establish whether non-traditional pedagogies at the secondary and post-secondary level are more effective than traditional lecture-based instruction. The research was conducted through an anonymous cross-sectional survey which included questions about educational …

Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk

SC Upstate Research Symposium

Purpose Statement: Several studies have shown that aerobic exercise can have a positive impact on alleviating symptoms experienced by individuals with Parkinson's disease (PD). Despite this evidence, the potential benefits of exercise for both PD patients and their care partners (PD dyad) remain unexplored. This research project investigates the effectiveness, therapeutic collaborations, and physical outcomes of a virtual reality (VR) tandem cycling program specifically designed for PD dyads.

Methods: Following approval from the Prisma Health Institutional Review Board, individuals with PD were identified and screened by clinical neurologists. The pre-testing measures for PD dyads (N=9) included emotional and cognitive status …

Development Of A Novel Biology Laboratory Course For Incarcerated Students, Elsa H.K. Spencer, Joanna R. Vondrasek

Inquiry: The Journal of the Virginia Community Colleges

Federal second chance Pell grants were recently made widely available to incarcerated students in the United States to fund undergraduate education. Piedmont Virginia Community College was a pilot site for this expansion and began full scale implementation of transfer-oriented associate degrees at three correctional centers in its service area. The college did not have a biology laboratory curriculum that would meet general education requirements and be feasible in a correctional center, where students do not have internet access or even reliable computer (word processing or spreadsheet) access and where materials are restricted for entry. This paper will serve to introduce …

How To Spark Bio Curiosity: An Innovative High School Biology Curriculum, Audrie Charles

Graduate Research Showcase

This project is a researched creative endeavor focused around the creation of an exemplary high school biology course. This presentation will showcase an original high school biology curriculum designed to ignite students’ innate curiosity and empower meaningful learning of core concepts like cell structure, genetics, evolution and ecology. Students revisit key ideas through a spiral curriculum that builds complexity, tackling open-ended problems and collaborating on hands-on inquiries like formulating hypotheses, designing experiments, collecting data and drawing evidence-based conclusions. Tangible projects allow students to demonstrate content knowledge in addition to critical thinking abilities like synthesizing concepts, evaluating claims and applying learning …

Whole Genome Sequencing Of The Whipple Azalea Garden, Afia Asamoah, Elizabeth Toth, Amy Vasudevan, Sarah Justice, Elizabeth D. Hasenmyer

Lux et Fides: A Journal for Undergraduate Christian Scholars

Taylor University houses a large collection of North American azaleas. Deciduous azalea species, like those found on campus, are vastly understudied. This project aims to provide publicly available genomic data which will be used to study the genetic basis behind their physical characteristics and their relatedness to other species.

Analysis Of Botulinum Toxin A And Interacting Proteins In Skeletal Muscle Cells: An Investigation Into The Mechanisms Of Botulinum Toxin A As A Treatment For Chronic Exertional Compartment Syndrome, Lauren R. Kee

ELAIA

Background Chronic exertional compartment syndrome (CECS) is a condition in which muscle tissue expands against the surrounding fascia during activity and is compressed along with the nerves and blood vessels within the muscle compartment, leading to abnormally high intracompartmental pressure (ICP) and debilitating pain. Treatment typically includes fasciotomy, which results in significant levels of CECS recurrence; however, botulinum toxin A (BoNT-A) injection has recently been seen to decrease both ICP and pain through an unknown mechanism with little to no recurrence. Methods In this study, PyRosetta was used to model the probability of docking interaction between BoNT-A light or heavy …

Variations In Student Approaches To Problem Solving In Undergraduate Biology Education, Jeremy L. Hsu, Rou-Jia Sung, Su L. Swarat, Alexandra J. Gore, Stephanie Kim, Stanley M. Lo

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Existing research has investigated student problem-solving strategies across science, technology, engineering, and mathematics; however, there is limited work in undergraduate biology education on how various aspects that influence learning combine to generate holistic approaches to problem solving. Through the lens of situated cognition, we consider problem solving as a learning phenomenon that involves the interactions between internal cognition of the learner and the external learning environment. Using phenomenography as a methodology, we investigated undergraduate student approaches to problem solving in biology through interviews. We identified five aspects of problem solving (including knowledge, strategy, intention, metacognition, and mindset) that define three …

Seeing Eye To Eye? Comparing Faculty And Student Perceptions Of Biomolecular Visualization Assessments, Josh T. Beckham, Daniel R. Dries, Bonnie L. Hall, Rarchel M. Mitton-Fry, Shelly Engelman, Charmita Burch, Roderico Acevedo, Pamela S. Mertz, Didem Vardar-Ulu, Swati Agrawal, Kristin M. Fox, Shane Austin, Margaret A. Franzen, Henry V. Jakubowski, Walter R. P. Novak, Rebecca Roberts, Alberto I. Roca, Kristen Procko

Chemistry Faculty Publications

While visual literacy has been identified as a foundational skill in life science education, there are many challenges in teaching and assessing biomolecular visualization skills. Among these are the lack of consensus about what constitutes competence and limited understanding of student and instructor perceptions of visual literacy tasks. In this study, we administered a set of biomolecular visualization assessments, developed as part of the BioMolViz project, to both students and instructors at multiple institutions and compared their perceptions of task difficulty. We then analyzed our findings using a mixed-methods approach. Quantitative analysis was used to answer the following research questions: …

Physically, Mentally, And Emotionally Drained, Kaitlin Medina

Regis University Student Publications (comprehensive collection)

Hormonal cycles play an essential role in the development and maturation of young boys and girls into men and women. As teenagers enter their late teens and early twenties, their hormonal cycles are primarily responsible for functions related to fertility and hormone production. During this period of time, these men and women are often in their collegiate years. Overall, the college experience is enjoyable for many students, but it can also be a very stressful time due to a difficult class load and the students’ need to balance their academic, social, and personal lives. Recent studies have analyzed the effects …

Ua94/6/18 Stephen Flora Student / Alumni Papers, Wku Archives

WKU Archives Collection Inventories

Records created by and about Stephen Flora during his years as a student at Western Kentucky University.

Reducing Food Scarcity: The Benefits Of Urban Farming, S.A. Claudell, Emilio Mejia

Journal of Nonprofit Innovation

Urban farming can enhance the lives of communities and help reduce food scarcity. This paper presents a conceptual prototype of an efficient urban farming community that can be scaled for a single apartment building or an entire community across all global geoeconomics regions, including densely populated cities and rural, developing towns and communities. When deployed in coordination with smart crop choices, local farm support, and efficient transportation then the result isn’t just sustainability, but also increasing fresh produce accessibility, optimizing nutritional value, eliminating the use of ‘forever chemicals’, reducing transportation costs, and fostering global environmental benefits.

Imagine Doris, who is …

Feminist Biology: Towards Gender Equity In The Biology Curriculum, Nicole Danos, Carla Y. Bonilla, Sofia Leung

Feminist Pedagogy

The current curriculum in STEM is a product of historically unequal representation of genders in the science community. As a result, most attention has been given to male biology, creating a knowledge gap that has affected our social and political perspectives, such as an underinvestment in women’s health research. Feminist biology seeks to provide equal time and weight to the impact of sex as a biological factor, using inclusive definitions of biological sex that go beyond the male/female binary. Feminist pedagogy is a method of teaching that involves engaged learning and reflection in order to create a community of learners …

Genealogical Vs Phylogenetic Mutation Rates: Answering A Challenge, Robert Carter

Proceedings of the International Conference on Creationism

There is a discrepancy between the mutation rate we can measure today and the rate at which evolution is supposed to have proceeded. The former is sometimes called the genealogical mutation rate, for it is obtained by comparing individuals whom we know to be related. The latter is sometimes called the phylogenetic mutation rate. It is calculated by counting the fixed differences between two species and dividing by the estimated time since their common ancestor. Genealogical mutation rates are generally several orders of magnitude faster than phylogenetic estimates. This causes problems for the evolutionary model. For example, using the genealogical …

Engaging Students In A Genetics Course-Based Undergraduate Research Experience Utilizing Caenorhabditis Elegans In Hybrid Learning To Explore Human Disease Gene Variants, Natalie Forte, Virginia Veasey, Bethany Christie, Amira Carter, Marli Hanks, Alan Holderfield, Taylor Houston, Anil Challa, Ashley Turner

Research, Publications & Creative Work

Genetic analysis in model systems using bioinformatic approaches provides a rich context for a concrete and conceptual understanding of gene structure and function. With the intent to engage students in research and explore disease biology utilizing the nematode Caenorhabditis elegans model, we developed a semester-long course-based undergraduate research experience (CURE) in a hybrid (online/in-person) learning environment—the gene-editing and evolutionary nematode exploration CURE (GENE-CURE). Using a combination of bioinformatic and molecular genetic tools, students performed structure-function analysis of disease-associated variants of uncertain significance (VUS) in human orthologs. With the aid of a series of workshop-style research sessions, students worked in teams …

Integrating Quantitative Skills Into Biology Courses, Kathleen Hoffman, Sarah Leupen, Hannah Pie, Michelle Starz-Gaiano, Patricia Turner, Tory Williams

Annual Symposium on Biomathematics and Ecology Education and Research

No abstract provided.

Investigating The Influence Of Assessment Question Framing On Undergraduate Biology Student Preference And Affect, Jeremy L. Hsu, Noelle Clark, Kate Hill, Melissa Rowland-Goldsmith

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Nearly all undergraduate biology courses rely on quizzes and exams. Despite their prevalence, very little work has been done to explore how the framing of assessment questions may influence student performance and affect. Here, we conduct a quasi-random experimental study where students in different sections of the same course were given isomorphic questions that varied in their framing of experimental scenarios. One section was provided a description using the self-referential term “you”, placing the student in the experiment; another section received the same scenario that used classmate names; while a third section's scenario integrated counterstereotypical scientist names. Our results demonstrate …

Instructors At A Crossroad: Perceptions Of Collaboration And Support Intersect With Intentions To Implement A Cure, Justin Berl

Dissertations and Theses

An ongoing crisis of student drop-off from undergraduate science, technology, engineering and mathematics (STEM) education has led to a sustained call over the last 15+ years for the increased implementation of updated practices in undergraduate STEM education. Though over the past few decades many researchers have developed and analyzed the efficacy of various evidence-based teaching practices (EBTPs) designed to improve the state of undergraduate STEM education throughout the country, the rate at which these EBTPs are implemented in undergraduate STEM classrooms remains low.

In order to better understand the specific factors that affect individual instructors' efforts to implement EBTPs, we …

Scents Of Place: Exploring Self, Place And Planet Through Botanical Fragrance, Jennifer L. Kitson, Donna M. Sweigart

Open Educational Resources

This learning module provides instructors with an experiential field guide for introducing students to the United Nations Inner Development Goals Framework through self-guided mindful smelling activities and reflection prompts related to botanical fragrance. The interdisciplinary nature of this module allows for use or adaptation in a wide range of courses looking for outdoor, place-based and self-guided experiential learning to explore the role of botanical fragrance for people, plants and pollinators. The overarching goal is to deepen students’ connections to their senses (and scents) of self, place and planet through exploring botanical fragrance with mindful smelling. The learning activities in this …

Deepening Undergraduate Students’ Thinking About Central Dogma Through Problem-Based Learning, Katherine Alberta Sharp, Rebecca Mc Nall Krall, Jeffrey Chalfant

Teacher Education and Certification Faculty Research & Creative Works

A Common Belief among Pre-Medical and Medical Students is that Biochemistry is Not Relevant to Practicing Medicine. the Problem-Based Approach of Case Studies Has Been Used in Medical Education to Scaffold the Application of Content to Clinical Cases, But Few Studies Report on a Similar Use in Undergraduate Biochemistry. Case Studies in Biochemistry and Related Disciplines Have Been Previously Reported as Increasing Learning Motivation and Supporting Depth of Knowledge. Additionally, Students Engaging in Case Studies Outperform Students in Traditional Instruction. the Objective of This Qualitative Case Study Was to Find How the Timing of a Medical Case Study within the …

Exploring Undergraduate Research Experiences And Perceptions Of Responsible And Ethical Conduct Of Research (Recr) Education In The Biological Sciences And (Bio)Chemistry Disciplines, Bernice Justina Caad

Open Access Theses & Dissertations

Increasing calls to reform undergraduate (UG) education within science, technology, engineering, and mathematics (STEM) disciplines have emphasized the importance of early exposure to responsible and ethical conduct of research (RECR) education. Historically, RECR has primarily been presented at the post-baccalaureate level, leaving many students without a foundational understanding of what responsible research ethics entails during the course of their undergraduate experience. Over the last decade, course-based undergraduate research experiences (CUREs) have emerged as a promising platform to establish expectations of responsible and ethical conduct through greater accessibility and inclusivity, starting at the freshman level. Interestingly, few studies have examined how …

A Professional Development Program For Science Adjunct Faculty: The Mentoring-Learning Community (Mlc), Linda B. Purvis, Jason D. Lang, Julie A. Luft

Georgia Journal of Science

Institutions of higher education have become increasingly dependent on adjunct faculty. These faculty members are often unfamiliar with current teaching strategies emphasizing an active learning approach. To support science adjunct faculty in learning about active learning, a professional development program was designed and implemented by the authors of this study, the Mentoring-Learning Community. The Mentoring-Learning Community program design was informed by literature regarding the use of professional development programs that focused on adjunct faculty. To determine the impact of this program, participants in the Mentoring-Learning Community were observed and interviewed over one semester. Mentoring-Learning Community participants transformed through all three …

Science Communication Training Imparts Confidence And Influences Public Engagement Activity, Christina M. Swords, Jerlym S. Porter, Amy J. Hawkins, Edwin Li, Melissa Rowland-Goldsmith, Matthew D. Koci, John F. Tansey, Nicole C. Woitowich

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The impacts of science are felt across all socio-ecological levels, ranging from the individual to societal. In order to adapt or respond to scientific discoveries, novel technologies, or biomedical or environmental challenges, a fundamental understanding of science is necessary. However, antiscientific rhetoric, mistrust in science, and the dissemination of misinformation hinder the promotion of science as a necessary and beneficial component of our world. Scientists can promote scientific literacy by establishing dialogues with nonexperts, but they may find a lack of formal training as a barrier to public engagement. To address this, the American Society for Biochemistry and Molecular Biology …

Fungi In Flux | Designing Regenerative Materials And Products With Mycelium, Arvind Bhallamudi

Masters Theses

As the world grapples with the escalating crisis of climate threats and environmental degradation, this research delves into the synergistic potential of design and biology, developing safe and sustainable materials for applications in prototyping, furniture and interior design. Harnessing the power of a unique organism - fungi, the study proposes an accessible, efficient, and resilient material resource system. It utilizes local waste streams and mycelium (the vegetative part of fungi) to grow functional structures. An experimental and small-scale protocol is modeled by testing bio-fabrication and bio-printing methods. The composites' performance qualities and characteristics are evaluated through mechanical testing and a …

Community-Derived Core Concepts For Neuroscience Higher Education, Audrey Chen, Kimberley A. Phillips, Jennifer E. Schaefer, Patrick M. Sonner

Biology Faculty Publications

Core concepts provide a framework for organizing facts and understanding in neuroscience higher education curricula. Core concepts are overarching principles that identify patterns in neuroscience processes and phenomena and can be used as a foundational scaffold for neuroscience knowledge. The need for community-derived core concepts is pressing, because both the pace of research and number of neuroscience programs are rapidly expanding. While general biology and many subdisciplines within biology have identified core concepts, neuroscience has yet to establish a community-derived set of core concepts for neuroscience higher education. We used an empirical approach involving more than 100 neuroscience educators to …

Student Perceptions Of Scholarly Writing: Student Generation Of Collaborative Rubrics To Score Scholarly Writing, Terri Enslein, Ed Kosack, Hanna Wetzel

Faculty Scholarship

Scholarly writing is an important skill in all fields of study. Despite a strong focus on writing in many courses, faculty and students have disparate expectations related to scholarly writing. Herein, a classroom exercise is presented in which students were asked to develop a rubric that would be used to evaluate their summative writing assessment. Students were provided with a list of elements that commonly represent good scholarly writing, asked to define what effectively demonstrating these elements looks like, and asked to assign the weight that would be given to each element. The weights given to each element by students …

Classic Iga-Vasculitis With Nephrotic Range Proteinuria - Rare Presentation In An Adult, Ella Teplitsky, Maryam Zafar, Abubakar Tauseef, Marissa Varghese, Joseph Thirumalareddy, Sunil Nair, Akshat Sood, Mohsin Mirza

Journal of Community Hospital Internal Medicine Perspectives

IgA vasculitis formerly known as Henoch-Schonlein Purpura is characterized by leukocytoclastic vasculitis and IgA immune complex in small vessels of the affected organ. IgA vasculitis can involve any organ system depending upon the deposition of the IgA immune complex. IgA vasculitis is a clinical diagnosis which manifest with abdominal pain, arthralgia/arthritis, palpable purpura, and kidney involvement. Occasionally, serum IgA levels or skin or kidney biopsy can help in confirming the diagnosis. Treatment is usually supportive, but studies have proved that prednisone or immunosuppressive agents can help in the prevention or progression of the disease. Hereby we present a case of …

Conceptualization And Perceptions Of Student Preparedness In Quantitative Reasoning Among Introductory Biology Faculty, Ann Cleveland

Electronic Theses and Dissertations

Quantitative reasoning (QR) is a crucial competency as undergraduate biology students complete their academic program and enter a workforce increasingly reliant on analyses of vast and complex data sets. The need to prepare biology majors for the 21^st century workforce was cited in Vision and Change: a Call to Action (American Association for the Advancement of Science [AAAS], 2011). The Vision and Change document also advocated for curriculum reform to incorporate QR instruction in undergraduate biology programs. Biology education researchers answered this call with a wealth of research examining undergraduate QR competencies, barriers and challenges to QR learning in …

An Overview Of Viruses And The Infamous Sars-Cov-2, Jake Sun

The Confluence

Background information on viruses is first presented which include topics like evolution, ecology, history, identification, structure, and application. The novel SARS-CoV-2, which causes COVID-19, pandemic originated in Wuhan, China in December 2019. Millions of people were infected with the virus in a short time period causing urgent concern worldwide. The purpose of this review is to provide a brief and general understanding of the SARS-CoV-2 to increase awareness and actions toward preventive measures. COVID-19 is a (+) ssRNA spherical enveloped virion that causes primarily respiratory illnesses. The S protein interacts with ACE-2 receptors on the host cell to gain entry …