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Articles 1 - 30 of 1210
Full-Text Articles in Biology
Effects Of Scion And Rootstock On Arbuscular Mycorrhizal Symbiosis And Spore Communities In Vitis Vinifera, Nicholas Vergara, Stephen Bentivenga
Effects Of Scion And Rootstock On Arbuscular Mycorrhizal Symbiosis And Spore Communities In Vitis Vinifera, Nicholas Vergara, Stephen Bentivenga
STEM Student Research Symposium Posters
Arbuscular mycorrhizal fungi (AMF) are obligate root symbionts that extend host nutrient uptake in exchange for photosynthate. Nearly all commercial wine grapes (Vitis vinifera) are grafted onto American rootstocks selected for phylloxera resistance, drought tolerance, and vigor, meaning the root system interfacing with soil fungi is genetically distinct from the fruiting scion. Whether root system origin shapes AMF association remains poorly resolved, particularly in sandy, low-fertility soils. We compared AMF colonization and spore communities across four rootstock–scion combinations (Cabernet Franc and Merlot scions, own-rooted and riparian rootstock) at William Heritage® Winery in Mullica Hill, NJ. Fine roots were cleared, stained, …
Comparison Of Arbuscular Mycorrhizal Fungal Colonization And Spore Communities Between Clover-Dominated Cover Crop And Restored Native Grass Systems, Nicholas Vergara, Stephen Bentivenga
Comparison Of Arbuscular Mycorrhizal Fungal Colonization And Spore Communities Between Clover-Dominated Cover Crop And Restored Native Grass Systems, Nicholas Vergara, Stephen Bentivenga
STEM Student Research Symposium Posters
Arbuscular mycorrhizal fungi (AMF) are obligate root symbionts that extend host nutrient uptake in exchange for photosynthate. Restored native grasslands and cover-cropped fields represent contrasting management strategies applied to former conventional farmland, differing in both tillage frequency and plant diversity, yet how these strategies shape AMF association in sandy, low-fertility soils remains largely understudied. We compared AMF colonization and spore communities between two adjacent sites converted approximately three years prior at the Bishop Farmstead, Southampton Township, NJ: a restored grassland dominated by Panicum virgatum and an agricultural field under white and red clover cover (Trifolium repens, T. pratense). Fine roots …
Oncogenic E-Cadherin-Dependent Metastasis And Potential Therapeutic Interventions, Madison K. Duenas, Anjela Anand, Paige Cano, Ralph Boccia, Mary Alpaugh
Oncogenic E-Cadherin-Dependent Metastasis And Potential Therapeutic Interventions, Madison K. Duenas, Anjela Anand, Paige Cano, Ralph Boccia, Mary Alpaugh
STEM Student Research Symposium Posters
Oncogenic E-cadherin-dependent metastasis is a paradoxical mechanism of cancer progression whereby E-cadherin, a cell-to-cell adhesion protein that normally suppresses tumor invasion, instead promotes the formation of cohesive cell tumor clusters that collectively invade surrounding tissues and metastasize. This phenomenon has been extensively studied using inflammatory breast cancer (IBC) models, including the MARY-X xenograft and SUM149 cell line, while comparisons with other breast cancer models such as MDA-MB-231 continue to provide insight into E-cadherin-independent metastatic mechanisms. This project reviews recent literature investigating the molecular mechanisms behind it and evaluates emerging therapeutic strategies targeting E-cadherin-associated cellular pathways. Laboratory techniques, including spheroid generation …
Exploring The Therapeutic Potential Of Kinetin In Allergic Contact Dermatitis, Hamna Muzaffar
Exploring The Therapeutic Potential Of Kinetin In Allergic Contact Dermatitis, Hamna Muzaffar
Thesis/ Dissertation Defenses
Allergic contact dermatitis is T cell mediated inflammatory skin disorder commonly studied using contact hypersensitivity mouse model. It induces local inflammation and further evidence suggests that gut microbiome also contributes to disease progression. However, kinetin, a natural plant hormone modulates these immune processes. After TNCB successfully induces CHS, kinetin treatment resulted in significant reduction in serum IgE levels while its effect on ear swelling and histological changes were modest. Microbiome analysis revealed no major difference in alpha diversity instead beta diversity demonstrated increased microbial heterogeneity in TNCB-treated mice group. Conversely, Kinetin-treated groups exhibited a microbial profile similar to wild type …
Making (Heat)Waves: Intermittent Thermal Stress Effects On Beet Armyworm (Spodoptera Exigua) Growth To Eclosion, Shane Dreher, Swayamjit Ray
Making (Heat)Waves: Intermittent Thermal Stress Effects On Beet Armyworm (Spodoptera Exigua) Growth To Eclosion, Shane Dreher, Swayamjit Ray
Research and Creative Works Expo
In this study, we demonstrated how application of heat stress, followed by rapid cooling, affected the rate at which beet armyworm caterpillars gained weight, entered pupation and exited their pupae as moths via eclosion.
Digging Deep Into Curation: A Guide To Creating A Local Fossil Museum, Syd Joheim, René Shroat-Lewis
Digging Deep Into Curation: A Guide To Creating A Local Fossil Museum, Syd Joheim, René Shroat-Lewis
Research and Creative Works Expo
In Arkansas, the dissemination of educational content related to evolution and natural history is often constrained by prevailing cultural dynamics. This has resulted in a significant gap in the exposure of primary and secondary school students to foundational concepts in natural history and physical sciences. Even the state’s most popular science and history museums often intentionally exclude exhibits that risk upsetting a large portion of their visitors, further exacerbating the issue. As a consequence, many children do not receive proper education on natural history and physical sciences. To address this educational deficiency, researchers identified and cataloged specimens from a collection …
Influence Of Pollinator Island Patch Size On Forb Establishment And Pollinator Networks In Palouse Prairie Restoration, Yaelle Esther Reeve
Influence Of Pollinator Island Patch Size On Forb Establishment And Pollinator Networks In Palouse Prairie Restoration, Yaelle Esther Reeve
2026 Symposium
The Palouse Prairie Ecoregion is one of North America’s most endangered grassland ecosystems, with less than 1% retaining native vegetation. Restoration efforts have struggled to re-establish ecologically important native forbs and the plant–pollinator interactions necessary for long-term community stability. Spatial configuration of floral resources is known to influence pollinator foraging behavior and interaction network structure, yet few studies have evaluated how planting scale affects both plant establishment and pollinator community assembly in early-stage prairie restoration. My research aims to evaluate how variations in the size (0.1, 1, and 10 m²) of grouped wildflower plantings (pollinator islands) affect native forb establishment, …
The Effects Of Water Quality On The Physiological Responses Of Daphnia Magna, Sara Al Shekha, Alexis Avila-Hernandez
The Effects Of Water Quality On The Physiological Responses Of Daphnia Magna, Sara Al Shekha, Alexis Avila-Hernandez
COD Library Student Research and Award Symposium
After conducting research on the effects of water quality on the physiological response of Daphnia magna, a common freshwater invertebrate, the biological stress response significantly differed in heart rates among groups, which differed from the original hypothesis after exposing the invertebrates to various samples of local pond water.
Faculty Sponsor: Professor Lynda Randa
Life History, Stock Status, And Movement Ecology Of Narrow-Barred Spanish Mackerel, Scomberomorus Commerson (Lacépède, 1800) In The Southern Arabian Gulf, Mohamed Abdulla Almusallami
Life History, Stock Status, And Movement Ecology Of Narrow-Barred Spanish Mackerel, Scomberomorus Commerson (Lacépède, 1800) In The Southern Arabian Gulf, Mohamed Abdulla Almusallami
Thesis/ Dissertation Defenses
The narrow-barred Spanish mackerel, Scomberomorus commerson, is the most commercially valuable pelagic fish species in the Arabian Gulf. This thesis integrated three studies to comprehensively assess the life history, stock status, and movement ecology of this species in Abu Dhabi waters. Life history traits were characterized from data collected during a 15-month monitoring program (January 2019–May 2020). Fork length ranged from 30.5 to 132 cm. Growth parameters were k = 0.14–0.15 year⁻¹ and L∞ = 128.9–135.4 cm for males and females, respectively. Size-at-maturity (Lm₅₀) was 78.7 cm FL for females and 69.7 cm FL for males. The spawning season occurred …
Expanding The Fossil Record Of Hippopotamodon (Suidae, Artiodactyla) From The Hasnot Area, Siwalik, Pakistan, Muhammad Ilyas, Rana Mehroz Fazal, Sayyed Ghyour Abbas, Misbah Faiz, Kiran Aftab, Abdul Ghaffar, Khizar Samiullah, Luke Holbrook
Expanding The Fossil Record Of Hippopotamodon (Suidae, Artiodactyla) From The Hasnot Area, Siwalik, Pakistan, Muhammad Ilyas, Rana Mehroz Fazal, Sayyed Ghyour Abbas, Misbah Faiz, Kiran Aftab, Abdul Ghaffar, Khizar Samiullah, Luke Holbrook
STEM Student Research Symposium Posters
The suid genus Hippopotamodon with its type species H. sivalense, is well known from Upper Miocene deposits in Eurasia. Its taxonomic history has been characterized by considerable instability, including early misassignments to genera such as Sus and Potamochoerus, and subsequent reclassifications involving Propotamochoerus, Dicoryphochoerus, and Microstonyx. This confusion primarily resulted from an overreliance on variable dental and canine morphology. Subsequent systematic revisions attempted to resolve these issues by proposing synonymies among these taxa, although debate has continued regarding the relationship between Hippopotamodon and Microstonyx. Recent work supports the synonymy of these taxa based on shared diagnostic features across Eurasian material. …
Discovery And Characterization Of Three Novel Bacteriophages Infecting Arthrobacter Globiformis: Crescenzo (Ay), Gerri43 (Fr), & Roberts (Fr), Gabrielle Achinko, Maximillan Castro, Evan Chernyenko, Kelley Crescenzo, Natalie Horchuck, Jessica Lee, Mattie Mcmahon, Heidi Meehan, Sandra Orjih, Kanishka Poudel, Kaitlyn Roberts, Alex Bogush, Matthew Farber, Marina Bogush
Discovery And Characterization Of Three Novel Bacteriophages Infecting Arthrobacter Globiformis: Crescenzo (Ay), Gerri43 (Fr), & Roberts (Fr), Gabrielle Achinko, Maximillan Castro, Evan Chernyenko, Kelley Crescenzo, Natalie Horchuck, Jessica Lee, Mattie Mcmahon, Heidi Meehan, Sandra Orjih, Kanishka Poudel, Kaitlyn Roberts, Alex Bogush, Matthew Farber, Marina Bogush
STEM Student Research Symposium Posters
Bacteriophages are viruses that infect bacteria and are increasingly important in applications ranging from agriculture and food safety to phage therapy. In this study, we isolated and characterized three novel phages, Gerri43, Crescenzo, and Roberts, from soil samples collected in Greenwich, New Jersey, and from the Rowan University campus in Glassboro, New Jersey, using Arthrobacter globiformis as the host bacterium. Phages were recovered using standard enrichment and purification approaches. After initial isolation, multiple rounds of plaque purification and serial dilution were performed to obtain clonal populations. High-titer lysates were then prepared by flooding webbed plates. Electron microscopy showed that all …
Impact Of Human Disturbance On Moth Populations In Ecuador, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Impact Of Human Disturbance On Moth Populations In Ecuador, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Science Seminar
Habitat disturbance in the temperate zone has been shown to negatively impact moth biodiversity and population size through a reduction in moth food resources and light pollution. Our study sought to understand how human activity impacts moth population numbers and diversity (# unique taxa) in the tropics. Specifically, we sampled moth population and diversity using light traps on two different nights in a disturbed habitat (Mera township, Ecuador) and on two nights at a nearby ecolodge situated in dense tropical forest. Significantly fewer moths were observed during trapping sessions in the township, and many fewer distinct taxa were noted when …
Patterns Of Moth Diversity In Relationship To Human Disturbance And Forest Type, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Patterns Of Moth Diversity In Relationship To Human Disturbance And Forest Type, Gianna Jones, Abbie Miller, Esther Frederickson, Grace Glerum
Science Seminar
Moths play a vital role in the health of tropical ecosystems, acting as important pollinators and food resources for a variety of species. Unfortunately, human habitat disturbance has been associated with declines in moth populations and diversity. To explore the impacts of habitat disturbance on taxonomic diversity in the tropics, we sampled moth populations at two different locations in the Pastaza Province (Mera township and an undisturbed forest at Tamandua Ecolodge). Though small in population (
The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Starman, Hayley Ponn
The Impacts Of Wing-Flashing By Northern Mockingbirds On Foraging, Parental Care, And Reproductive Success, Anna Starman, Hayley Ponn
Science Seminar
Foraging efficiency may be enhanced by flashing patches of white wing and tail feathers and has been documented in several avian species. Northern Mockingbirds (Mimus polyglottos, NOMO) exhibit this "wing-flashing" (WF) behavior while foraging, during displays, and in response to predators. In NOMOs, WF has been hypothesized to increase foraging success, but previous findings are inconclusive. To further investigate the biological role(s) of WF behavior in NOMOs, the ventral surface of white primary feathers of male NOMOs were artificially darkened and the foraging and provisioning rates of undarkened (control) males and their mates were compared. While foraging, undarkened males performed …
Foraging Load Size And Activity In Leaf-Cutter Ants In Rural And Urban Ecuador, Natalie Tollison, Anna Starman
Foraging Load Size And Activity In Leaf-Cutter Ants In Rural And Urban Ecuador, Natalie Tollison, Anna Starman
Science Seminar
Leaf cutter ants are important ecosystem engineers in Neotropical forests, moving a significant amount of nutrients from the forest canopy to the soil. We were interested in understanding how time (day vs. night), weather, and level of human disturbance would impact foraging activity in leaf-cutter ants (Atta spp.). To investigate, we sampled activity levels and leaf size along leaf-cutter ant trails in Mera (urban, N=17) and Tamandua (forest, N=27). During the daytime, ants in Mera carried significantly more leaves that were larger in size as well as more total items than did ants in Tamandua. Factors such as the level …
Biodiversity And Diet Patterns: Environmental Impacts On Ecuadorian Birds, Holly Hylton, Fin Bolt, Gracyn Herbst
Biodiversity And Diet Patterns: Environmental Impacts On Ecuadorian Birds, Holly Hylton, Fin Bolt, Gracyn Herbst
Science Seminar
The current biodiversity crisis is of great concern, particularly to bird species in temperate and tropical areas. We examined avian biodiversity patterns in Ecuador, one of the most bird-biodiverse countries in the world (1650+ species). In January 2026, birds were surveyed (visual and auditory) for 30 minutes on consecutive days in 4 different locations that differed in the degree of human development. As expected, species richness was much higher in undisturbed locations than disturbed locations. In addition, our comparison of dietary patterns between sites showed a much higher proportion of frugivorous and insectivorous species in areas with less human disturbance …
Parasite Prevalence In Local Grasshopper Populations, Lucia B. Freund, Ali Gronquist
Parasite Prevalence In Local Grasshopper Populations, Lucia B. Freund, Ali Gronquist
Research & Creative Achievement Day
Spur-throated grasshoppers (genus Melanoplus) are a common agricultural pest in North America. Spur-throated grasshoppers are also a common host to several parasitic organisms. Horsehair worms (phylum Nematomorpha) are parasitic organisms known for their ability to manipulate the behavior of its insect host, particularly grasshoppers and crickets, by urging the host to enter water so it can complete its life cycle. Along with being a host to parasitic worms, they are a frequent target of grasshopper mites. Grasshopper mites (Eutrombidium locustarum) is a short-lived parasite that can negatively influence the reproductive ability of their host. Because grasshoppers are a major agricultural …
Characterization Of Bacteria In Cattle Specimens, Jacob D. Hanson, Josie M. Tieskoetter
Characterization Of Bacteria In Cattle Specimens, Jacob D. Hanson, Josie M. Tieskoetter
Research & Creative Achievement Day
Cattle nasal cavities provide a favorable environment for microbial colonization and can habit a wide population of bacteria, including opportunistic and pathogenic species. The objective of this research was to isolate, characterize, and identify bacteria present is nasal swap specimen collected from multiple calves. Samples were cultured and analyzed using selective and differential media, Gram staining, spore staining, and a range of biochemical assays. Several bacterial species were identified including the genus Corynebacterium and Streptococcus while some isolates could not be identified using classical biochemical methods alone. These results demonstrate that calf nasal specimens commonly contain diverse bacterial populations, some …
Skin Pattern As A Potential Monitoring Tool For Frog Populations, Lídize Sagarnaga Rivera, Virginie Rolland Dr., Lorin Neuman-Lee Dr.
Skin Pattern As A Potential Monitoring Tool For Frog Populations, Lídize Sagarnaga Rivera, Virginie Rolland Dr., Lorin Neuman-Lee Dr.
Create@State
Skin pattern as a potential monitoring tool for frog populations
Population monitoring, which requires identifying individuals, is crucial for species conservation. Common techniques involve marking, which can harm animals and alter their behaviors. Natural markings are an alternative not yet explored for amphibians. Yet, the traditional method with elastomers (fluorescent implants) is invasive and not completely reliable—the tag may become lost or hard to see. The American green tree frog (Dryophytes cinereus) possesses naturally occurring and distinct golden dots on their dorsal side. Therefore, we aim to assess whether patterns of golden dots on the skin of green …
Amyloid Beta-42 Neurotoxicity In Drosophila Retinal Development, Shay O. Sims, Pierce Duncan, Malachi Abon, Jacob G. Smith
Amyloid Beta-42 Neurotoxicity In Drosophila Retinal Development, Shay O. Sims, Pierce Duncan, Malachi Abon, Jacob G. Smith
Create@State
Alzheimer's disease (AD) represents one of the most prevalent neurodegenerative disorders globally. Thus far, the underlying mechanisms associated with the pathogenesis of AD are innately elusive. Two hallmarks associated with the progression of AD exist, including Amyloid-Beta 42 (Aβ42) protein plaque formation and hyperphosphorylation of tau proteins in neurons. Amyloid-beta is known to concentrate with other neuronal proteins as complexes form, including the cytoskeletal protein actin. However, whether actin contributes to neuronal decline in AD is unknown. To further understand the cellular cascades associated with AD, we investigated the role of cytoskeleton dynamics in modulating oxidative stress and neuroinflammation within …
Variation In Infection Prevalence Of Splendidofilaria Pectoralis Across Alaskan Grouse Populations, Anahi Garcia Valdez, Diego Martinez
Variation In Infection Prevalence Of Splendidofilaria Pectoralis Across Alaskan Grouse Populations, Anahi Garcia Valdez, Diego Martinez
Create@State
In recent years, rapid climate change has altered species distributions worldwide and influenced parasite transmission dynamics in wildlife systems. Parasite infections play an important role in shaping patterns of disease distribution across species and populations. Understanding variation in infection prevalence across geographic regions and host demographic groups is essential for interpreting these patterns. Splendidofilaria pectoralis is a filarial nematode that infects the connective tissues of grouse (Aves: Tetraonini) in Alaska and has been moving northward as the climate warms. However, relatively little is known about the variation in prevalence of the nematode across geography and demography. This project examines variation …
Potential Applications Of Thymus Vulgaris In Dental Care: A Review Of Antimicrobial And Oral Health Benefits, Lakenzia Z. Ham
Potential Applications Of Thymus Vulgaris In Dental Care: A Review Of Antimicrobial And Oral Health Benefits, Lakenzia Z. Ham
Undergraduate Research Conference
This research proposal focuses on how common thyme (Thymus vulgaris) can be used in dental care. There has been more interest in natural products for dental health because some common dental treatments can have side effects or lead to antibiotic resistance. Thyme contains natural compounds like thymol and carvacrol that help kill bacteria, reduce inflammation, and prevent buildup on teeth.
The purpose of this study is to investigate the current scientific literature to see the effectiveness of thyme in preventing common oral health problems like cavities, gum disease, and bad breath. Research shows that thyme can fight bacteria …
Late-Season Forb Availability And Bumble Bee Foraging Patterns In Iowa’S Restored Prairies And Suburban Gardens, Isaac De Young, Ellary Carson, Mya Cole, Tucker Draayer, Sharon Huffman, Naomi Johnson, Jasmine Lux, Genesis Maldonado, Caitlin Olson, Maelee Rodenburg, Jordan Shull, Travis Sweeney, Arianna Van Donkelaar, Laurie Furlong, Todd Tracy
Late-Season Forb Availability And Bumble Bee Foraging Patterns In Iowa’S Restored Prairies And Suburban Gardens, Isaac De Young, Ellary Carson, Mya Cole, Tucker Draayer, Sharon Huffman, Naomi Johnson, Jasmine Lux, Genesis Maldonado, Caitlin Olson, Maelee Rodenburg, Jordan Shull, Travis Sweeney, Arianna Van Donkelaar, Laurie Furlong, Todd Tracy
Celebration of Research
Pollinators are essential to terrestrial ecosystems, and bumble bees are among the most effective pollinators in the United States (Hatfield et al., 2012). They pollinate forbs (non-grass herbaceous flowering plants), including crops, garden plants, and native prairie species (Dumroese et al., 2016). Their ability to travel long distances, forage in cool temperatures, and buzz-pollinate makes them critical to both wild and agricultural productivity (Mola & Williams et al., 2019). Research shows that bumble bee populations have declined in recent decades due to habitat loss, reduced floral resources, pesticide exposure, and climate change (IPBES, 2016).
Northwest Iowa is dominated by agriculture, …
Eagleeye Is Landing: Discovery Of Cytotoxic And Defense Genes In A Cluster A16 Mycobacteriophage, Clara Bader, Kylie Foss, Mallory Gramstad, Korver Hupke, Jenna Kluxdal, Elsie Larson, Ayda Maassen, Adriana Sandbulte, Dane Schoenborn, Emma Steinhardt, Alexa Trover, Sara S. Tolsma
Eagleeye Is Landing: Discovery Of Cytotoxic And Defense Genes In A Cluster A16 Mycobacteriophage, Clara Bader, Kylie Foss, Mallory Gramstad, Korver Hupke, Jenna Kluxdal, Elsie Larson, Ayda Maassen, Adriana Sandbulte, Dane Schoenborn, Emma Steinhardt, Alexa Trover, Sara S. Tolsma
Celebration of Research
EagleEye is a temperate bacteriophage, which was isolated on the host, Mycobacterium smegmatis mc2 155 from soil collected in Houston, TX. It is classified as cluster A16. We are using a systematic genetic screen to uncover functions of phage genes for which the function is unknown. We cloned each gene into the pExTra plasmid and assayed phage gene individually for two phenotypes: cytotoxicity, the ability to interfere with host cell growth, and defense, the ability to protect the host cell from infection by other phages. We have cloned all but 15 of EagleEye’s 95 protein-coding genes. Thus far, we have …
If You Give A Mouse A Phage, Peyton Abraham, Princess Bola-Lawal, Amelia Brown, Anne Eveland, Jenna Kluxdal, Elsie Larson, Gabrielle O'Bannon, Leonardo Romo, Sara S. Tolsma
If You Give A Mouse A Phage, Peyton Abraham, Princess Bola-Lawal, Amelia Brown, Anne Eveland, Jenna Kluxdal, Elsie Larson, Gabrielle O'Bannon, Leonardo Romo, Sara S. Tolsma
Celebration of Research
Island3 (Cluster I1) and Sbash (Cluster I2) are Mycobacteriophages that have a high degree of genetic similarity—especially in the region of their genomes that include genes for structural proteins. Because their structural proteins appear so similar, we hypothesized that antibodies raised against Island3 would cross-react with Sbash and vice versa. To test our hypothesis, we immunized female BALB/c mice with phage high titer lysates or filtered M. smegmatis (control), collected serum, and used the antibodies in ELISA and Western Blot assays. We observed less cross-reactivity than we expected.
Annotation Of Bacteriophages Redraider89, Superherocarly, Cherrycola, And Kouch, Brianne Brandt, Mya Cole, Matthew Dawkins, Julia De Vos, Isaac De Young, Hannah Gordon, Landon Greve, Brody Hoverstein, Mia Kellenberger, Genesis Maldonado, Charlotte Pritchard, Noah Robinson, Leonardo Romo, Mackenzie Schram, Grace Timm, Arianna Van Donkelaar, Kamea Van Kalsbeek, Byron Noordewier, Sara S. Tolsma
Annotation Of Bacteriophages Redraider89, Superherocarly, Cherrycola, And Kouch, Brianne Brandt, Mya Cole, Matthew Dawkins, Julia De Vos, Isaac De Young, Hannah Gordon, Landon Greve, Brody Hoverstein, Mia Kellenberger, Genesis Maldonado, Charlotte Pritchard, Noah Robinson, Leonardo Romo, Mackenzie Schram, Grace Timm, Arianna Van Donkelaar, Kamea Van Kalsbeek, Byron Noordewier, Sara S. Tolsma
Celebration of Research
Phages are important research tools and can be used as an alternative to antibiotics. They are abundant and diverse. Genome annotation is used to better understand phage diversity as well as individual phages for use in the lab and clinic. We annotated the genomes of four novel phages: RedRaider89, SuperHeroCarly, Kouch, and CherryCola. All four phages were discovered by Northwestern College students. CherryCola is a Cluster DC1 phage that infects Gordonia terrae. It has 92 predicted protein-coding genes. RedRaider89 (Cluster B1) and SuperHeroCarly (Cluster D1) infect Mycobacterium smegmatis mc²155. RedRaider89 has 99 predicted protein-coding genes and SuperHeroCarly has 87 …
Understanding The Role Of Lipid Metabolism On Pancreatic Cancer Metastasis, Luke Fischer, Kylie Foss, Jacob Lewis, Joshua Lewis, Emma Steinhardt, Megan Vangarven, Cody Rozeveld
Understanding The Role Of Lipid Metabolism On Pancreatic Cancer Metastasis, Luke Fischer, Kylie Foss, Jacob Lewis, Joshua Lewis, Emma Steinhardt, Megan Vangarven, Cody Rozeveld
Celebration of Research
Pancreatic cancer is one of the deadliest types of cancer due to late-stage detection and early metastasis. Other than smoking, one of the few known risk factors for pancreatic cancer is obesity (1). On the cellular level, excess fat can promote cell migration and invasion (2). However, the exact fat utilization pathway remains unknown. We propose that lysosomes may be exploited in pancreatic cancer to break down fat and provide energy for metastasis and invasion.
Bacterial 2-Hybrid Assay: Interactions Of Phage Island3'S Gene 36 And Mycobacterium Smegmatis Gene Products, Elsie L. Larson, Sara Tolsma
Bacterial 2-Hybrid Assay: Interactions Of Phage Island3'S Gene 36 And Mycobacterium Smegmatis Gene Products, Elsie L. Larson, Sara Tolsma
Celebration of Research
Island3 is a Cluster I1 bacteriophage that infects Mycobacterium smegmatis. Northwestern College students are performing systematic genetic screens to identify Island3 genes that are cytotoxic or protect host cells from infection by other phages (defense). We identified Island3’s gp36 as a cytotoxic gene. Now we are using a bacterial two-hybrid assay to identify a host protein(s) interaction partner. We hypothesize that host proteins that bind gp36 will reveal the mechanism by which gp36 confers cytotoxicity.
Investigation Of Northwest Iowa Pollinator Communities Using Two Survey Methods, Ellary Carson, Mya Cole, Isaac De Young, Sharon Huffman, Naomi Johnson, Genesis Maldonado, Maelee Rodenburg, Travis Sweeney, Tark Griebel, Laurie Furlong, Todd Tracy
Investigation Of Northwest Iowa Pollinator Communities Using Two Survey Methods, Ellary Carson, Mya Cole, Isaac De Young, Sharon Huffman, Naomi Johnson, Genesis Maldonado, Maelee Rodenburg, Travis Sweeney, Tark Griebel, Laurie Furlong, Todd Tracy
Celebration of Research
The ecological services of insect pollinators are well established and the documented decline in pollinator biodiversity is of great concern. Baseline data and continued monitoring are essential as we ongoing trends in pollinator communities and evaluate efforts supporting their recovery. Using two survey methods, our study provides pollinator community data at two conservation sites in Northwest Iowa. In September of 2025, we used three colors of pan traps (blue, yellow, and white) to investigate pollinator communities at a small, reconstructed prairie (Buena Vista County Park) and a nearby partially restored native prairie (The Nature Conservancy Glacial Hills Preserve). We also …
Studying The Role Of Combitional Flavonoids Against Toxicity Of Chemothrapeutic Drugs In Human Fibroblast Cells, Hussain Al Zouabi
Studying The Role Of Combitional Flavonoids Against Toxicity Of Chemothrapeutic Drugs In Human Fibroblast Cells, Hussain Al Zouabi
Thesis/ Dissertation Defenses
Chemotherapy remains the primary treatment strategy for cancers; however, its clinical efficacy is often limited by severe toxic effects resulting in normal cells. The study investigated the protective potential of the flavonoids epigallocatechin-3-O-gallate (EGCG) and quercetin, used in combination, against chemotherapy-induced toxicity in human fibroblast F-180 cells. Cells were exposed to three commonly used chemotherapeutic agents, doxorubicin, cisplatin, and etoposide, in the presence or absence of EGCG and quercetin at concentrations of 25 and 50 μM. cells viability was assessed using the MTT assay, while oxidative stress and antioxidant capacity were evaluated by intracellular reactive oxygen species (ROS) and total …