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Full-Text Articles in Biology

Investigating The Role Of Cellular Senescence On Vestibular Dysfunction In Repetitive Mild Traumatic Brain Injury, Michael Volyanyuk Jun 2026

Investigating The Role Of Cellular Senescence On Vestibular Dysfunction In Repetitive Mild Traumatic Brain Injury, Michael Volyanyuk

Dissertations

Vestibular dysfunction is a prevalent and persistent consequence of mild traumatic brain injury (mTBI). Clinical reports reveal that women experience vestibular deficits more frequently than men following mTBI. Despite the high prevalence and debilitating nature of vestibular symptoms, preclinical literature evaluating mTBI-associated vestibular impairments is limited. Emerging evidence demonstrates that cellular senescence is involved in the pathological molecular sequela of mTBI. It has been shown that senescence contributes to cognitive deficits following repetitive mTBI (rmTBI); however, its role in rmTBI-associated vestibular dysfunction remains unexplored. This body of work investigated the role of cellular senescence on rmTBI-induced vestibular dysfunction in both …


Draft Genome Of Corynebacterium Glycinophilum S209 Isolated From Healthy Human Skin, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti Oct 2025

Draft Genome Of Corynebacterium Glycinophilum S209 Isolated From Healthy Human Skin, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti

Biology: Faculty Publications and Other Works

Corynebacterium glycinophilum is an understudied species of this genus, although it has been identified in dairy products as well as the human skin microbiome. Recently, we isolated a strain from the skin of a healthy human female, and here, we present the draft genome of this isolate, C. glycinophilum S209.


Draft Genome Sequences Of Staphylococcus Species Isolated From Urine Samples From Asymptomatic Females, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti Sep 2025

Draft Genome Sequences Of Staphylococcus Species Isolated From Urine Samples From Asymptomatic Females, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti

Biology: Faculty Publications and Other Works

The female urinary tract is host to several different Staphylococcus species, both uropathogens and commensals. To further investigate these species, we sequenced the genomes of four isolates from voided urine samples collected from asymptomatic (“healthy”) females: Staphylococcus aureus U215, Staphylococcus haemolyticus U117, and Staphylococcus hominis strains U224 and U226.


Streptococcus Anginosus Of The Urogenital Tract: Evidence Of The Same Strain Across Anatomical Sites Of The Same Females, Helen Appleberry, Jennifer Garcia-Israel, Leah Boger, Swarnali Banerjee, Alan J. Wolfe, Catherine Putonti Sep 2025

Streptococcus Anginosus Of The Urogenital Tract: Evidence Of The Same Strain Across Anatomical Sites Of The Same Females, Helen Appleberry, Jennifer Garcia-Israel, Leah Boger, Swarnali Banerjee, Alan J. Wolfe, Catherine Putonti

Biology: Faculty Publications and Other Works

Background: Streptococcus anginosus has been found to colonize multiple anatomical sites of the human body, including the oral cavity, gastrointestinal tract, skin, vagina, blood, and urinary tract. It is frequently isolated from catheterized urine samples obtained from adult females most often with lower urinary tract symptoms, but also on occasion from those without symptoms. Our prior genome analysis of 166 S. anginosus genomes identified two distinct groups, one – which we here call group Urinae – exhibits a tropism for the urinary tract. Results: Here we sequenced 100 isolates collected from different urogenital sites, including isolates from urine (both catheterized …


Draft Genome Sequences Of Staphylococcus Hominis Strains O226 And O218 And Micrococcus Luteus O220 Isolated From The Buccal Swabs Of Healthy Individuals, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti Sep 2025

Draft Genome Sequences Of Staphylococcus Hominis Strains O226 And O218 And Micrococcus Luteus O220 Isolated From The Buccal Swabs Of Healthy Individuals, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti

Biology: Faculty Publications and Other Works

To investigate the genomic features of rare oral commensals in healthy individuals, we present the draft genome sequences of Staphylococcus hominis strains O226 and O218 and Micrococcus luteus strain O220. All three of these isolates were purified from buccal swab samples collected from healthy female participants.


Draft Genome Sequence Of Staphylococcus Aureus N208 Isolated From A Nasal Swab Of A Healthy Female, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti Sep 2025

Draft Genome Sequence Of Staphylococcus Aureus N208 Isolated From A Nasal Swab Of A Healthy Female, Sandra Jablonska, Lila Nelson, Grace Finger, Alex Kula, Catherine Putonti

Biology: Faculty Publications and Other Works

Staphylococcus aureus, a common member of the healthy human microbiota, is an opportunistic pathogen. To investigate the genomic features of this species in healthy individuals, we present the draft genome sequence of S. aureus N208, isolated from a nasal swab collected from a healthy female participant.


Genome Sequences For Nine Streptococcus Anginosus Strains Isolated From Female Urogenital Samples, Helen Appleberry, Olive Kolar, Saad Ahmed, Omar Al Khalili, Inga Astrauskas, Adel Choubkha, Abraham Dulli, Anna Gamal, Elina Greljo, Samiah Iqbal, Neelesh Kanduri, Adam Kawamleh, Emma Kress, Walter Mccain, Sophia Meza, Madison Mikolaitis, Amal Naqvi, Emily Ngo, Jackie Ostiguin, Vedant Patel, Alan J. Wolfe, Catherine Putonti, Alex Kula Jul 2025

Genome Sequences For Nine Streptococcus Anginosus Strains Isolated From Female Urogenital Samples, Helen Appleberry, Olive Kolar, Saad Ahmed, Omar Al Khalili, Inga Astrauskas, Adel Choubkha, Abraham Dulli, Anna Gamal, Elina Greljo, Samiah Iqbal, Neelesh Kanduri, Adam Kawamleh, Emma Kress, Walter Mccain, Sophia Meza, Madison Mikolaitis, Amal Naqvi, Emily Ngo, Jackie Ostiguin, Vedant Patel, Alan J. Wolfe, Catherine Putonti, Alex Kula

Biology: Faculty Publications and Other Works

Streptococcus anginosus is a common inhabitant of the female urinary tract. Comparative genomics suggests that strains from female urogenital samples are distinct from S. anginosus strains isolated from other anatomical sites. Here, we present three complete and six draft genome assemblies of S. anginosus isolated from urine, vaginal swabs, and a perineal swab.


A Glyoxal-Specific Aldehyde Signaling Axis In Pseudomonas Aeruginosa That Influences Quorum Sensing And Infection, Christopher J. Corcoran, Bonnie J. Cuthbert, David G. Glanville, Mailyn Terrado, Diana Valverde Mendez, Benjamin P. Bratton, Daniel E. Schemenauer, Valerie L. Tokars, Thomas G. Martin, Lawrence W. Rasmussen, Matthew C. Madison, Andrew F. Maule, Joshua W. Shaevitz, Boo Shan Tseng, Julian P. Whitelegge, Catherine Putonti, Amit Gaggar, Jordan R. Beach, Jonathan A. Kirk, Alfonso Mondragón, Abby R. Kroken, Jonathan P. Allen, Celia W. Goulding, Andrew T. Ulijasz Jul 2025

A Glyoxal-Specific Aldehyde Signaling Axis In Pseudomonas Aeruginosa That Influences Quorum Sensing And Infection, Christopher J. Corcoran, Bonnie J. Cuthbert, David G. Glanville, Mailyn Terrado, Diana Valverde Mendez, Benjamin P. Bratton, Daniel E. Schemenauer, Valerie L. Tokars, Thomas G. Martin, Lawrence W. Rasmussen, Matthew C. Madison, Andrew F. Maule, Joshua W. Shaevitz, Boo Shan Tseng, Julian P. Whitelegge, Catherine Putonti, Amit Gaggar, Jordan R. Beach, Jonathan A. Kirk, Alfonso Mondragón, Abby R. Kroken, Jonathan P. Allen, Celia W. Goulding, Andrew T. Ulijasz

Biology: Faculty Publications and Other Works

The universally conserved α-oxoaldehydes glyoxal (GO) and methylglyoxal (MGO) are toxic metabolic byproducts whose accumulation can lead to cell death. In the absence of a known, natural inducer of the GO-specific response in prokaryotes, we exploited RNA-seq to define a GO response in the bacterial pathogen Pseudomonas aeruginosa. The highest upregulated operon consisted of the known glyoxalase (gloA2) and an antibiotic monooxygenase (ABM) domain of unknown function - renamed here Aldehyde responsive quorum-sensing Inhibitor (ArqI). The arqI-gloA2 operon is highly specific to GO induction and ArqI protein responds by migrating to the flagellar pole. An ArqI atomic structure revealed several …


Complete Genome Sequence Of Staphylococcus Haemolyticus Umb6531b, Isolated From A Perineal Swab, Alex Kula, Olive Kolar, Karolina Gilewicz, Zainab Qureshi, Anmol Singh, Alan J. Wolfe, Catherine Putonti Jul 2025

Complete Genome Sequence Of Staphylococcus Haemolyticus Umb6531b, Isolated From A Perineal Swab, Alex Kula, Olive Kolar, Karolina Gilewicz, Zainab Qureshi, Anmol Singh, Alan J. Wolfe, Catherine Putonti

Biology: Faculty Publications and Other Works

Staphylococcus haemolyticus UMB6531B was isolated from a perineal swab of a female with overactive bladder symptoms and sequenced to better characterize opportunistic pathogens of the female urogenital tract. Here, we present the complete genome sequence, which includes the chromosome as well as two complete plasmid sequences.


Complete Genome Sequence Of Vaginal Swab Isolate Enterococcus Faecalis Umb6935b, Including Two Complete Plasmids, Olive Kolar, Helen Appleberry, Alan J. Wolfe, Alex Kula, Catherine Putonti Jul 2025

Complete Genome Sequence Of Vaginal Swab Isolate Enterococcus Faecalis Umb6935b, Including Two Complete Plasmids, Olive Kolar, Helen Appleberry, Alan J. Wolfe, Alex Kula, Catherine Putonti

Biology: Faculty Publications and Other Works

Enterococcus faecalis has been identified as a member of the vaginal community of healthy females, in addition to its association with vaginitis and urinary tract infections. Here we present the hybrid assembly of an E. faecalis strain, UMB6935B, isolated from a vaginal swab from a female with overactive bladder symptoms.


Regulation Of Spermatogenesis By The Notch Signaling Pathway, Emma O'Flaherty Jun 2025

Regulation Of Spermatogenesis By The Notch Signaling Pathway, Emma O'Flaherty

Master's Theses

The Notch signaling pathway plays a significant role in gonad development and spermatogenesis, but little is known about its specific targets in the testis. The Drosophila testis contains two populations of stem cells: germline stem cells and cyst stem cells, which give rise to differentiating germline and somatic cyst cells, respectively. Notch signaling is activated in the somatic cyst cells by the Delta ligand from the germline in a region of the testes coined the “transition zone”, where somatic cyst cells progress from early cyst cells surrounding gonialblasts and 2-cell germline cysts to late cyst cells surrounding 16-cell spermatocyte cysts. …


Anthropogenic Litter In Freshwater Ecosystems: Effect On Ecosystem Processes And Spatial Distribution, Emily Johnson Jun 2025

Anthropogenic Litter In Freshwater Ecosystems: Effect On Ecosystem Processes And Spatial Distribution, Emily Johnson

Master's Theses

The rapid increase of plastic production and disposal into the environment has resulted in anthropogenic litter (i.e., trash; AL) becoming a global problem. In aquatic ecosystems, macro- and microplastics are long-lived, mobile, and interact with the physical and chemical components of aquatic ecosystems. Our objectives were to: (1) assess the impact of microplastic pollution on the ecosystem processes of ecosystem metabolism and N2 flux in an oligotrophic lake and (2) to assess the abundance and assemblage of anthropogenic litter in a large urban river. For objective (1), we added microplastics at a range of concentrations to littoral mesocosms. Ecosystem metabolism …


Phage Therapy For Urinary Tract Infections: Progress And Challenges Ahead, Chase J. Morgan, Haley Atkins, Alan J. Wolfe, Linda Brubaker, Saima Aslam, Catherine Putonti, Michael B. Doud, Lindsey A. Burnett May 2025

Phage Therapy For Urinary Tract Infections: Progress And Challenges Ahead, Chase J. Morgan, Haley Atkins, Alan J. Wolfe, Linda Brubaker, Saima Aslam, Catherine Putonti, Michael B. Doud, Lindsey A. Burnett

Biology: Faculty Publications and Other Works

Introduction and Hypothesis: Urinary tract infection (UTI) treatment is a growing public health concern owing to increasing antimicrobial resistance. Phage therapy, an alternative or adjunctive treatment to antibiotics, has the potential to address this challenge. However, clinical use of phage therapy is hindered by knowledge gaps and inconsistent reporting. The objective was to review the current state of phage therapy for UTIs and highlight research priorities that can optimize phage clinical efficacy. Methods: Current literature on UTI phage therapy was examined, focusing on the lack of standardized phage susceptibility testing, phage characterization, and microbiological assessments during and after treatment. Results: …


Refinement Of Megakaryocyte Lineage Commitment In Hematopoietic Stem And Progenitor Cells During Postnatal And Adult Hematopoiesis, Ryan Michael Mack Mar 2025

Refinement Of Megakaryocyte Lineage Commitment In Hematopoietic Stem And Progenitor Cells During Postnatal And Adult Hematopoiesis, Ryan Michael Mack

Dissertations

Mammalian hematopoiesis ensures the continuous production of specialized blood cells, yet the mechanisms that govern megakaryocyte/erythroid (MK/E) bifurcation remain incompletely understood. While HSPCs sustain all blood lineages, how transient waves of progenitors arise and adapt from fetal to adult stages is less clear. This gap in knowledge limits our capacity to precisely manipulate platelet and red blood cell outputs in both developmental and therapeutic contexts. Using refined gating strategies and various bulk- and single-cell transcriptomics, we dissected the traditional “common myeloid progenitor” and Multipotent Progenitor (MPP) compartment into multiple functionally distinct subsets (C1, C2, C3). Within C1, an ESAM⁺ fraction …


Plasmodium Berghei Subpellicular Microtubule Protein-1 (Pbspm-1) Is A Microtubule Stabilizing Protein That Affects Schizont Development, Manuel Joseph Widuch Jan 2025

Plasmodium Berghei Subpellicular Microtubule Protein-1 (Pbspm-1) Is A Microtubule Stabilizing Protein That Affects Schizont Development, Manuel Joseph Widuch

Master's Theses

In eukaryotes, microtubules (MTs) are regulated by microtubule-associated proteins (MAP), only a few of which have been characterized in the malaria parasite to date. Here we present the functional characterization of STOP axonemal protein 1 (SAXO1) of the rodent parasite Plasmodium berghei. The protein exhibits high sequence and organizational conservation to the subpellicular microtubule protein 1 (SPM1) of the apicomplexan parasite Toxoplasma gondii and SAXO1 of Trypanosoma brucei. SAXO1 proteins are conserved in most eukaryotes where they form a protein family. We refer to this protein as PbSPM1. It is a 38 kD protein that is organized into an N-terminal …


Exploring The Ecological Relevance Of Biotic And Abiotic Stressors In Structuring Legume Microbial Communities, Cian Dotson Jan 2025

Exploring The Ecological Relevance Of Biotic And Abiotic Stressors In Structuring Legume Microbial Communities, Cian Dotson

Dissertations

Heavy metal hyperaccumulation is prevalent throughout plant evolution, particularly in the legume family (Fabaceae), and acts as a presumed chemical defense against herbivory. However, heavy metal hyperaccumulation can have non-target impacts on other biological interactors including plant-microbe interactions. This information is important given the interest in utilizing hyperaccumulating plants for phytoremediation of anthropogenically contaminated soils. Here we employ a greenhouse experiment manipulating selenium level along with 16S rRNA gene amplicon sequencing methods to explore the effect of selenium on the prokaryotic microbiome of the selenium hyperaccumulator Astragalus crotalariae and non-accumulator Astragalus lentiginosus var. borreganus. Regardless of hyperaccumulator status, both plant …


Evaluation Of Bacteriophage Infection Of Enterococcus Faecalis In A Monolayer, Alexandria Osborn Jan 2025

Evaluation Of Bacteriophage Infection Of Enterococcus Faecalis In A Monolayer, Alexandria Osborn

Dissertations

Enterococcus faecalis is one of the first colonizers of the human gastrointestinal tract, and it plays a role in the intestinal immune development at the very early stages of life. However, it is also an opportunistic pathogen, capable of translocating across the mucosal barrier to cause systemic infections. E. faecalis is also linked to infections including endocarditis, recurrent urinary tract infections (rUTIs), bacteremia, wound infections, meningitis, root canal infections, intra-abdominal and pelvic infections, and septicemia. Persistent enterococcal opportunistic infections have been associated with the production of virulence factors and sharing of antibiotic resistance genes, thus making E. faecalis difficult to …


Effects Of Nitrogen, Phosphorus And The Fungicide Azoxystrobin Additions On Larval And Post-Metamorphic Fitness Of American Toads (Anaxyrus Americanus), Michael Vosburgh Jan 2025

Effects Of Nitrogen, Phosphorus And The Fungicide Azoxystrobin Additions On Larval And Post-Metamorphic Fitness Of American Toads (Anaxyrus Americanus), Michael Vosburgh

Dissertations

Since European settlement, vast areas of U.S. land have been modified by humans. In the Midwest, an estimated 99% of native grasslands have been replaced by agriculture and urban development. Such alternations have replaced native habitat, redefined hydrology and introduced a wide array of chemicals into aquatic ecosystems. Modern agricultural practices utilize fertilizers and pesticides to maximize crop production. These chemicals frequently runoff into surrounding waters, potentially effecting aquatic organisms. One group of organism thought to be susceptible to agricultural contaminants are amphibians. Amphibians are vulnerable to pollution due, in part, to their permeable skin and biphasic life history. Global …


Drivers Of Microparticles Abundance In Freshwater Fish And Macroinvertibrates, Elizabeth Kazmierczak Sep 2024

Drivers Of Microparticles Abundance In Freshwater Fish And Macroinvertibrates, Elizabeth Kazmierczak

Master's Theses

Anthropogenic microparticles (MP) (i.e., particles < 5 mm) are defined as materials of manufactured origin found in the environment. They are widespread and a rapidly emerging global contaminant. MP include microplastics (< 5 mm), as well as other microfibers or particles, which can be synthetic, semi-synthetic and non-synthetic. Rivers are a critical source of plastics to oceans, and MP within rivers are retained in part though biological processes, including ingestion. MP ingestion by freshwater biota varies by proximity to point sources (e.g., wastewater treatment plants; WWTP), overall environmental concentrations, and trophic level and functional feeding groups, but few studies have examined these factors together. In our first study we examined fish collected in the North Shore Channel of the Chicago River to determine MP abundance within organisms. We then compared trophic position (i.e., δ15N) and proximity to a WWTP. With all species combined, MP concentration were not significantly different across study sites, but stable isotopes increased downstream. Considered individually, MP abundance relative to WWTP proximity varied by species, which we attributed to habitat preference and mobility. In a second project, we collected macroinvertebrates from three different watersheds in North America and compared the abundance of MP in macroinvertebrates to concentration within the environment (i.e., water column, surface, and benthic). Functional feeding groups were a significant predictor in the amount of microparticles found in macroinvertebrates. Additionally, the concentration of water column microparticles showed a positive relationship with all macroinvertebrate’s microparticle abundance. Results will aid in understanding the ecological impacts of MPs on aquatic food webs and the pathways in which they can enter.


The Skin Microbiome And Cutaneous T-Cell Lymphoma, Gail Hillary Lantaca Enriquez Sep 2024

The Skin Microbiome And Cutaneous T-Cell Lymphoma, Gail Hillary Lantaca Enriquez

Master's Theses

Skin microbiota is associated with disease activity in cutaneous T-cell lymphoma (CTCL). A common treatment for CTCL, narrowband ultraviolet B (nbUVB) phototherapy, has shown to shape the skin microbiome in association with disease improvement in other skin disorders such as atopic dermatitis. To assess the effect of nbUVB phototherapy on the skin microbiome, we performed a longitudinal analysis of skin samples of CTCL patients receiving nbUVB. We found that the treatment led to increased bacterial diversity and reduced abundances of Staphylococcus aureus and Staphylococcus lugdunensis, both bacteria known to be pathogenic. These findings imply that nbUVB treatment changes the skin …


Impacts Of Stormwater And Land Cover On The Abundance, Transport, And Composition Of Anthropogenic Litter In Urban Watersheds, Bailey Austin Schwenk Sep 2024

Impacts Of Stormwater And Land Cover On The Abundance, Transport, And Composition Of Anthropogenic Litter In Urban Watersheds, Bailey Austin Schwenk

Master's Theses

Anthropogenic litter (AL; trash) is defined as any manufactured item that ends up in the environment. AL consists of many different materials including glass, metal, and plastic, the latter of which typically represents a dominant constituent and has been a major focus of research. Plastic litter and other AL types are pervasive to all types of ecosystems, are persistent in the environment, and are increasing. Rivers are a major conduit transporting AL to oceans. However, rivers also retain and transform AL. More research is needed to understand AL dynamics within rivers, which will improve global models of AL movement and …


Pattern, Process And The Evolution Of Sexual Dimorphism In Three-Spine Stickleback Fish Gasterosteus Aculeatus From Vancouver Island, British Columbia, Katie Van Dame Sep 2024

Pattern, Process And The Evolution Of Sexual Dimorphism In Three-Spine Stickleback Fish Gasterosteus Aculeatus From Vancouver Island, British Columbia, Katie Van Dame

Master's Theses

Males and females of a species often differ from one another in phenotype—a phenomenon known as sexual dimorphism. Sexual dimorphism is most often attributed to sexual selection. However, sexual dimorphism also derives from natural selection when resource competition generates disruptive selection favoring specialization on different resources, resulting in niche partitioning and the evolution of dimorphism in traits related to competition. Sexual dimorphism may be an important route to increased individual fitness (i.e., more resources, more survival). For example, ecologically driven divergent selection between sexes may derive from differences in their environments, resulting in the evolution of dimorphism in traits related …


Draft Genome Sequences Of Four Corynebacterium Amycolatum Strains Isolated From Female Urine Samples, Alex Kula, Grace Chilton, James Damaso, Yusef Golzar, Fatima Rushnaiwala, Helen Appleberry, Alan J. Wolfe, Catherine Putonti Sep 2024

Draft Genome Sequences Of Four Corynebacterium Amycolatum Strains Isolated From Female Urine Samples, Alex Kula, Grace Chilton, James Damaso, Yusef Golzar, Fatima Rushnaiwala, Helen Appleberry, Alan J. Wolfe, Catherine Putonti

Biology: Faculty Publications and Other Works

Corynebacterium amycolatum is an emerging pathogen of the urinary tract. Here, we present the draft genomes for four strains isolated from urine collected from symptomatic and asymptomatic female participants.


Two Draft Genome Assemblies Of Staphylococcus Aureus Strains Isolated From A Cheek Swab Of A Healthy Female Participant, Alex Kula, Sandra Jablonska, Lexi Avalos, Tyler Jensen, Helen Appleberry, Catherine Putonti Aug 2024

Two Draft Genome Assemblies Of Staphylococcus Aureus Strains Isolated From A Cheek Swab Of A Healthy Female Participant, Alex Kula, Sandra Jablonska, Lexi Avalos, Tyler Jensen, Helen Appleberry, Catherine Putonti

Biology: Faculty Publications and Other Works

Staphylococcus aureus is an opportunistic pathogen often commensal within the nasal and oral cavities. Here we present the genomes of S. aureus O139-S and O139-NS, both isolated from the cheek swab of a healthy female participant. While found in the same sample, the two strains displayed distinct colony morphologies.


Draft Genomes Of Klebsiella Aerogenes, Klebsiella Huaxiensis, And Klebsiella Michiganensis Isolates From The Urinary Tract, Alex Kula, Muna Arman, Helen Appleberry, Alan J. Wolfe, Catherine Putonti Aug 2024

Draft Genomes Of Klebsiella Aerogenes, Klebsiella Huaxiensis, And Klebsiella Michiganensis Isolates From The Urinary Tract, Alex Kula, Muna Arman, Helen Appleberry, Alan J. Wolfe, Catherine Putonti

Biology: Faculty Publications and Other Works

Several Klebsiella spp. can be the cause of urinary tract infections. Here we present the draft genome assemblies for four urinary isolates of three Klebsiella spp.: Klebsiella aerogenes UMB7541, Klebsiella michiganensis UMB11142 and UMB11423, and Klebsiella huaxiensis UMB11391 to further explore the genetic diversity of Klebsiella in the urinary tract.


Draft Genomes Of Neisseria Perflava Umb0578, Proteus Mirabilis Umb8339, And Enterococcus Faecalis Umb7967 Isolated From Urine Samples, Alex Kula, Ali Khan, Megan Martinez, Jevan Terry, Helen Appleberry, Alan J. Wolfe, Catherine Putonti Aug 2024

Draft Genomes Of Neisseria Perflava Umb0578, Proteus Mirabilis Umb8339, And Enterococcus Faecalis Umb7967 Isolated From Urine Samples, Alex Kula, Ali Khan, Megan Martinez, Jevan Terry, Helen Appleberry, Alan J. Wolfe, Catherine Putonti

Biology: Faculty Publications and Other Works

The urinary tract of females harbors a variety of microorganisms, both for those with and without symptoms. Here, we present the draft genome sequences of three isolates from urine samples—Neisseria perflava UMB0578, Proteus mirabilis UMB8339, and Enterococcus faecalis UMB7967.


Draft Genomes Of One Staphylococcus Haemolyticus And Five Staphylococcus Lugdunensis Strains Isolated From Catheterized Urine Samples Of Females, Helen Appleberry, Haaris Anjum, Taleah Cage, Kayla Jarm, Haashir Khan, Lizzie Proctor, Junelle Saroca, Alan J. Wolfe, Catherine Putonti, Alex Kula Aug 2024

Draft Genomes Of One Staphylococcus Haemolyticus And Five Staphylococcus Lugdunensis Strains Isolated From Catheterized Urine Samples Of Females, Helen Appleberry, Haaris Anjum, Taleah Cage, Kayla Jarm, Haashir Khan, Lizzie Proctor, Junelle Saroca, Alan J. Wolfe, Catherine Putonti, Alex Kula

Biology: Faculty Publications and Other Works

Although Staphylococcus haemolyticus and Staphylococcus lugdunensis are members of the normal human flora, they also can cause infection. Here, we present the draft genomes of five strains of S. lugdunensis and one strain of S. haemolyticus isolated from transurethral catheterized urine samples from different females experiencing lower urinary tract symptoms.


Evolutionary Patterns Of Anolis Lizard Skulls: An Investigation In Geometric Morphometrics And An Educational Exploration Of Structure And Function, Katherine Beyer Starr Aug 2024

Evolutionary Patterns Of Anolis Lizard Skulls: An Investigation In Geometric Morphometrics And An Educational Exploration Of Structure And Function, Katherine Beyer Starr

Master's Theses

This study explores the evolutionary patterns of Anolis lizard skulls and integrates findings into a curriculum focused on elucidating the structure and function of a lizard's head. The first objective was to develop an understanding of how the evolutionary patterns, of an extraordinary group of lizards (Anolis) compares to their relatives. Most of the prior research on Anolis morphology has focused on the post-cranium because of its significance towards subdivision of the arboreal habitat. But the group’s remarkable diversity in head shape has been seriously under-investigated. By performing geometric morphometric analysis of skull shape across a large sample of anoles …


Draft Genome Sequences Of An Enterobacter Hormaechei And Providencia Rettgeri Isolated From The Urine Of A Male Experiencing A Catheter-Associated Urinary Tract Infection, Helen Appleberry, Michaela Brady, Samantha Webster, Alan J. Wolfe, Catherine Putonti, Alex Kula Jul 2024

Draft Genome Sequences Of An Enterobacter Hormaechei And Providencia Rettgeri Isolated From The Urine Of A Male Experiencing A Catheter-Associated Urinary Tract Infection, Helen Appleberry, Michaela Brady, Samantha Webster, Alan J. Wolfe, Catherine Putonti, Alex Kula

Biology: Faculty Publications and Other Works

Catheter-associated urinary tract infections (CAUTIs) can be caused by a variety of microbes. Here, we describe the draft genome assemblies of two species—Enterobacter hormaechei and Providencia rettgeri—purified from the catheterized urine sample of a male diagnosed with a CAUTI.


Draft Genome Assemblies Of One Lactobacillus Gasseri Strain And Two Lactobacillus Jensenii Strains Isolated From Voided Urine Samples, Alex Kula, Natalie Stegman, Catherine Putonti Jul 2024

Draft Genome Assemblies Of One Lactobacillus Gasseri Strain And Two Lactobacillus Jensenii Strains Isolated From Voided Urine Samples, Alex Kula, Natalie Stegman, Catherine Putonti

Biology: Faculty Publications and Other Works

We present the draft genome for three Lactobacillus strains isolated from female urine specimens: Lactobacillus gasseri UMB1673, Lactobacillus jensenii UMB1855, and Lactobacillus jensenii UMB5069. Focusing on strains within the female urinary microbiome can provide a more well-rounded understanding of the microbial community and its influence on health and disease.