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When 10 Trials Are Better Than 1000: An Evidentiary Perspective On Trial Sampling, Edward K. Cheng 2012 Vanderbilt University Law School

When 10 Trials Are Better Than 1000: An Evidentiary Perspective On Trial Sampling, Edward K. Cheng

Vanderbilt Law School Faculty Publications

In many mass tort cases, separately trying all individual claims is impractical, and thus a number of trial courts and commentators have explored the use of statistical sampling as a way of efficiently processing claims. Most discussions on the topic, however, implicitly assume that sampling is a “second best” solution: individual trials are preferred for accuracy, and sampling only justified under extraordinary circumstances. This Essay explores whether this assumption is really true. While intuitively one might think that individual trials would be more accurate at estimating liability than extrapolating from a subset of cases, the Essay offers three ways in …


Muscle Organization In Individuals With And Without Pain And Joint Dysfunction, J. C. Nickel, Y. M. Gonzalez, W. D. McCall, R. Ohrbach, D. B. Marx, H. Liu, L. R. Iwasaki 2012 University of Missouri-Kansas City

Muscle Organization In Individuals With And Without Pain And Joint Dysfunction, J. C. Nickel, Y. M. Gonzalez, W. D. Mccall, R. Ohrbach, D. B. Marx, H. Liu, L. R. Iwasaki

Department of Statistics: Faculty Publications

Central nervous system organization of masticatory muscles determines the magnitude of joint and muscle forces. Validated computer-assisted models of neuromuscular organization during biting were used to determine organization in individuals with and without temporomandibular disorders (TMD). Ninety-one individuals (47 women, 44 men) were assigned to one of four diagnostic groups based on the presence (+) or absence (-) of pain (P) and bilateral temporomandibular joint disc displacement (DD). Electromyography and bite-forces were measured during right and left incisor and molar biting. Two three-dimensional models employing neuromuscular objectives of minimization of joint loads (MJL) or muscle effort (MME) simulated biting tasks. …


Learning Interdisciplinary Pedagogies, Alison J. Friedow, Erin E. Blankenship, Jennifer L. Green, Walter Stroup 2012 University of Nebraska–Lincoln

Learning Interdisciplinary Pedagogies, Alison J. Friedow, Erin E. Blankenship, Jennifer L. Green, Walter Stroup

Department of Statistics: Faculty Publications

Advocates of interdisciplinary teaching and learning in higher education suggest that interdisciplinary courses “promise a wide range of desirable educational outcomes for students” (Newell 1994: 35). These outcomes include enhanced affective and cognitive abilities, increased understanding of multiple perspectives, greater appreciation for ambiguity, and superior capacities for creative thinking, among others (35). Despite claims about the possibilities interdisciplinary learning offers, we have few examples of how faculty from different disciplines work together to create interdisciplinary classroom environments where such outcomes can occur. In short, more examples of how faculty from different disciplines actually develop, engage, and revise interdisciplinary pedagogies with …


Drosophila Melanogaster Selection For Survival Of Bacillus Cereus Infection: Life History Trait Indirect Responses, Junjie Ma, Andrew K. Benson, Stephen D. Kachman, Zhen Hu, Lawrence G. Harshman 2012 University of Nebraska - Lincoln

Drosophila Melanogaster Selection For Survival Of Bacillus Cereus Infection: Life History Trait Indirect Responses, Junjie Ma, Andrew K. Benson, Stephen D. Kachman, Zhen Hu, Lawrence G. Harshman

Department of Statistics: Faculty Publications

To study evolved resistance/tolerance in an insect model, we carried out an experimental evolution study using D. melanogaster and the opportunistic pathogen B. cereus as the agent of selection. The selected lines evolved a 3.0- to 3.3-log increase in the concentration of spores required for 50% mortality after 18–24 generations of selection. In the absence of any treatment, selected lines evolved an increase in egg production and delayed development time. The latter response could be interpreted as a cost of evolution. Alternatively, delayed development might have been a target of selection resulting in increased adult fat body function including production …


Prediction In Several Conventional Contexts, Bertrand Clarke, Jennifer clarke 2012 University of Miami

Prediction In Several Conventional Contexts, Bertrand Clarke, Jennifer Clarke

Department of Statistics: Faculty Publications

We review predictive techniques from several traditional branches of statistics. Starting with prediction based on the normal model and on the empirical distribution function, we proceed to techniques for various forms of regression and classification. Then, we turn to time series, longitudinal data, and survival analysis. Our focus throughout is on the mechanics of prediction more than on the properties of predictors.


Comment On Article By Sancetta, Bertrand Clarke 2012 University of Miami

Comment On Article By Sancetta, Bertrand Clarke

Department of Statistics: Faculty Publications

This paper makes a landmark contribution in three senses.

First, it provides many results that are fundamentally important in their own right. I refer specifically to Theorems 3 and 8. Theorem 3 treats arbitrary loss functions by breaking the integral into two terms, one It, where a difference of losses is bounded and another, IIt, where a bound on the moments of a difference of losses must be used. (All notation here is the same as the author's unless noted otherwise.) The treatment of these two terms reveals the role of the relative entropy and how the tails of the …


The Dirty “S” Word: Innovative Teaching Techniques For Counselor Educators Facilitating Learning In Statistics And Research, Rebecca Tadlock-Marlo, Megan Michalak 2012 Eastern Illinois University

The Dirty “S” Word: Innovative Teaching Techniques For Counselor Educators Facilitating Learning In Statistics And Research, Rebecca Tadlock-Marlo, Megan Michalak

Faculty Research & Creative Activity

Innovative pedagogy will be presented and discussed to help make research a less painful class to both teach and learn. Foci include teaching methods, potential assignments, and suggestions for activities to help facilitate a more fluid learning process for counselors. Attendees will explore aspects of helping students overcome their fear of both statistics and research.


Retrospective Evaluation Of Admissions For Chemotherapy-Inducednausea, Vomiting, And Dehydration, Katelin Van Leer PharmaD, Janine Barnaby RPh, BCOP 2012 Lehigh Valley

Retrospective Evaluation Of Admissions For Chemotherapy-Inducednausea, Vomiting, And Dehydration, Katelin Van Leer Pharmad, Janine Barnaby Rph, Bcop

Department of Pharmacy

No abstract provided.


Arma-Garch Model Applied To Exchange-Traded Funds, Rebecca Davis 2012 University of Texas at El Paso

Arma-Garch Model Applied To Exchange-Traded Funds, Rebecca Davis

Open Access Theses & Dissertations

In this paper, time-varying volatility of some of the leading exchange-traded funds are studied. The ARMA mean equation with GARCH errors is used to model the series correlations and the conditional heteroscadesticity in the asset

returns. The conditional distributions of the standardized residuals are assumed to be skew-generalized error distribution. The high kurtosis and fat tail of the returns, were captured in all the data by fitting an ARMA-GARCH model with the conditional distribution of, skew-generalized error distribution.

Furthermore, the sample cross-correlations of these significant exchange-traded funds and the corresponding financial indices they mimic were computed. The empirical conclusion was …


Evaluation Of Repeated Biomarkers: Non-Parametric Comparison Of Areas Under The Receiver Operating Curve Between Correlated Groups Using An Optimal Weighting Scheme, Ping Xu 2012 University of South Florida

Evaluation Of Repeated Biomarkers: Non-Parametric Comparison Of Areas Under The Receiver Operating Curve Between Correlated Groups Using An Optimal Weighting Scheme, Ping Xu

USF Tampa Graduate Theses and Dissertations

Receiver Operating Characteristic (ROC) curves are often used to evaluate the prognostic performance of a continuous biomarker. In a previous research, a non-parametric ROC approach was introduced to compare two biomarkers with repeated measurements. An asymptotically normal statistic, which contains the subject-specific weights, was developed to estimate the areas under the ROC curve of biomarkers. Although two weighting schemes were suggested to be optimal when the within subject correlation is 1 or 0 by the previous study, the universal optimal weight was not determined. We modify this asymptotical statistic to compare AUCs between two correlated groups and propose a solution …


Linear Mixed-Effects Models: Applications To The Behavioral Sciences And Adolescent Community Health, Lizmarie Gabriela Maldonado 2012 University of South Florida

Linear Mixed-Effects Models: Applications To The Behavioral Sciences And Adolescent Community Health, Lizmarie Gabriela Maldonado

USF Tampa Graduate Theses and Dissertations

Linear mixed-effects (LME) modeling is a widely used statistical method for analyzing repeated measures or longitudinal data. Such longitudinal studies typically aim to investigate and describe the trajectory of a desired outcome. Longitudinal data have the advantage over cross-sectional data by providing more accuracy for the model. LME models allow researchers to account for random variation among individuals and between individuals.

In this project, adolescent health was chosen as a topic of research due to the many changes that occur during this crucial time period as a precursor to overall well-being in adult life. Understanding the factors that influence how …


Bayesian Inference On Mixed-Effects Models With Skewed Distributions For Hiv Longitudinal Data, Ren Chen 2012 University of South Florida

Bayesian Inference On Mixed-Effects Models With Skewed Distributions For Hiv Longitudinal Data, Ren Chen

USF Tampa Graduate Theses and Dissertations

Statistical models have greatly improved our understanding of the pathogenesis of HIV-1 infection

and guided for the treatment of AIDS patients and evaluation of antiretroviral (ARV) therapies.

Although various statistical modeling and analysis methods have been applied for estimating the

parameters of HIV dynamics via mixed-effects models, a common assumption of distribution is

normal for random errors and random-effects. This assumption may lack the robustness against

departures from normality so may lead misleading or biased inference. Moreover, some covariates

such as CD4 cell count may be often measured with substantial errors. Bivariate clustered

(correlated) data are also commonly encountered in …


Statistical Estimation Of Physiologically-Based Pharmacokinetic Models: Identifiability, Variation, And Uncertainty With An Illustration Of Chronic Exposure To Dioxin And Dioxin-Like-Compounds., Zachary John Thompson 2012 University of South Florida

Statistical Estimation Of Physiologically-Based Pharmacokinetic Models: Identifiability, Variation, And Uncertainty With An Illustration Of Chronic Exposure To Dioxin And Dioxin-Like-Compounds., Zachary John Thompson

USF Tampa Graduate Theses and Dissertations

Assessment of human exposure to environmental chemicals is inherently subject to uncertainty and variability. There are data gaps concerning the inventory, source, duration, and intensity of exposure

as well as knowledge gaps regarding pharmacokinetics in general. These gaps result in uncertainties in exposure assessment.

The uncertainties compound further with variabilities due to population variations regarding stage of life, life style, and susceptibility,

etc. Use of physiologically-based pharmacokinetic (PBPK) models promises to reduce the uncertainties and enhance extrapolation between species, between routes, from high to low dose, and from acute to chronic exposure. However, fitting PBPK models is challenging because of …


Statistical Content In Middle Grades Mathematics Textbooks, Maria Consuelo (suzie) Capiral Pickle 2012 University of South Florida

Statistical Content In Middle Grades Mathematics Textbooks, Maria Consuelo (Suzie) Capiral Pickle

USF Tampa Graduate Theses and Dissertations

Statistical Content in Middle Grades Mathematics Textbooks

Maria Consuelo (Suzie) Capiral Pickle

Abstract

This study analyzed the treatment and scope of

statistical concepts in four, widely-used, contemporary, middle

grades mathematics textbook series: Glencoe Math Connects,

Prentice Hall Mathematics, Connected Mathematics Project, and

University of Chicago School Mathematics Project. There were

three phases for the data analysis. Phase 1 addressed the location

and sequence of the statistical concepts. Phase 2 focused upon an

examination of the lesson narrative, its components and scope.

Phase 3 analyzed the level of cognitive demand required of the

students to complete the exercises, and the total …


Stochastic Modeling Of Network-Centric Epidemiological Processes, Divine Wanduku 2012 University of South Florida

Stochastic Modeling Of Network-Centric Epidemiological Processes, Divine Wanduku

USF Tampa Graduate Theses and Dissertations

The technological changes and educational expansion have created the heterogeneity in the human species. Clearly, this heterogeneity generates a structure in the population

dynamics, namely: citizen, permanent resident, visitor, and etc. Furthermore, as the heterogeneity in the population increases, the human mobility between meta-populations patches

also increases. Depending on spatial scales, a meta-population patch can be decomposed into sub-patches, for examples: homes, neighborhoods, towns, etc. The dynamics of human

mobility in a heterogeneous and scaled structured population is still its infancy level. We develop and investigate (1) an algorithmic two scale human mobility dynamic model for a meta-population. Moreover,the two …


Statistical Modeling And Analysis Of Breast Cancer And Pancreatic Cancer, Zahra Kottabi 2012 University of South Florida

Statistical Modeling And Analysis Of Breast Cancer And Pancreatic Cancer, Zahra Kottabi

USF Tampa Graduate Theses and Dissertations

Abstract

The object of the present study is to apply statistical modeling and estimate the mean of optimism of breast cancer patients as function of attribute variables; delay, education and age for each race of breast cancer patients. Moreover, to investigate the nonlinear association between optimism, education, age and delay with respect to each race and both. Furthermore, to develop differential equations that will characterize the behavior of the pancreatic cancer tumor size as a function of time. Having such differential equations, the mean solution of which once plotted will identify the rate of change of tumor size as a …


Multi-Time Scales Stochastic Dynamic Processes: Modeling, Methods, Algorithms, Analysis, And Applications, Jean-Claude Pedjeu 2012 University of South Florida

Multi-Time Scales Stochastic Dynamic Processes: Modeling, Methods, Algorithms, Analysis, And Applications, Jean-Claude Pedjeu

USF Tampa Graduate Theses and Dissertations

By introducing a concept of dynamic process operating under multi-time scales in sciences and engineering, a mathematical model is formulated and it leads to a system of multi-time scale stochastic differential equations. The classical Picard-Lindel\"{o}f successive approximations scheme is expended to the model validation problem, namely, existence and uniqueness of solution process. Naturally, this generates to a problem of finding closed form solutions of both linear and nonlinear multi-time scale stochastic differential equations. To illustrate the scope of ideas and presented results, multi-time scale stochastic models for ecological and epidemiological processes in population dynamic are exhibited. Without loss in generality, …


Stochastic Hybrid Dynamic Systems: Modeling, Estimation And Simulation, Daniel Siu 2012 University of South Florida

Stochastic Hybrid Dynamic Systems: Modeling, Estimation And Simulation, Daniel Siu

USF Tampa Graduate Theses and Dissertations

Stochastic hybrid dynamic systems that incorporate both continuous and discrete dynamics have been an area of great interest over the recent years. In view of applications, stochastic hybrid dynamic systems have been employed to diverse fields of studies, such as communication networks, air traffic management, and insurance risk models. The aim of the present study is to investigate properties of some classes of stochastic hybrid dynamic systems.

The class of stochastic hybrid dynamic systems investigated has random jumps driven by a non-homogeneous Poisson process and deterministic jumps triggered by hitting the boundary. Its real-valued continuous dynamic between jumps is described …


Quitline Fax Referrals – Increasing Enrollment And Outcomes, Alice Dalla-Palu MPA, CTTS-M, CAC, Jeanne Fignar AAS, Patricia Lavan RDH, BA, Kayshin Chan MPH 2012 Lehigh Valley Health Network

Quitline Fax Referrals – Increasing Enrollment And Outcomes, Alice Dalla-Palu Mpa, Ctts-M, Cac, Jeanne Fignar Aas, Patricia Lavan Rdh, Ba, Kayshin Chan Mph

Department of Emergency Medicine

No abstract provided.


Probability Of Identification: A Statistical Model For The Validation Of Qualitative Botanical Identification Methods, Robert A. LaBudde, James M. Harnly 2012 Old Dominion University

Probability Of Identification: A Statistical Model For The Validation Of Qualitative Botanical Identification Methods, Robert A. Labudde, James M. Harnly

Mathematics & Statistics Faculty Publications

A qualitative botanical identification method (BIM) is an analytical procedure that returns a binary result (1 = Identified, 0 = Not Identified). A BIM may be used by a buyer, manufacturer, or regulator to determine whether a botanical material being tested is the same as the target (desired) material, or whether it contains excessive nontarget (undesirable) material. The report describes the development and validation of studies for a BIM based on the proportion of replicates identified, or probability of identification (POI), as the basic observed statistic. The statistical procedures proposed for data analysis follow closely those of the probability of …


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