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Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook 2021 Duquesne University

Understanding The Effect Of Adaptive Mutations On The Three-Dimensional Structure Of Rna, Justin Cook

Undergraduate Research and Scholarship Symposium

Single-nucleotide polymorphisms (SNPs) are variations in the genome where one base pair can differ between individuals.1 SNPs occur throughout the genome and can correlate to a disease-state if they occur in a functional region of DNA.1According to the central dogma of molecular biology, any variation in the DNA sequence will have a direct effect on the RNA sequence and will potentially alter the identity or conformation of a protein product. A single RNA molecule, due to intramolecular base pairing, can acquire a plethora of 3-D conformations that are described by its structural ensemble. One SNP, rs12477830, which ...


Application Of Randomness In Finance, Jose Sanchez, Daanial Ahmad, Satyanand Singh 2021 CUNY New York City College of Technology

Application Of Randomness In Finance, Jose Sanchez, Daanial Ahmad, Satyanand Singh

Publications and Research

Brownian Motion which is also considered to be a Wiener process and can be thought of as a random walk. In our project we had briefly discussed the fluctuations of financial indices and related it to Brownian Motion and the modeling of Stock prices.


Retail Trading And Stock Volatility: The Case Of Robinhood, Cooper Jones 2021 Utah State University

Retail Trading And Stock Volatility: The Case Of Robinhood, Cooper Jones

All Graduate Plan B and other Reports

We examine the relation between Robinhood usership and stock market volatility. We show that daily fluctuations in Robinhood usership, which is used to proxy retail trading, significantly influence various measures of volatility. These results might suggest that Robinhood users contribute to noise trading as they are generally individuals trading on name recognition, media coverage, popularity, and familiarity of products, rather than on fundamental values. In our empirical approach, we find that the percentage increase in Robinhood usership Granger causes increases in daily stock volatility.


Use Of Linear Discriminant Analysis In Song Classification: Modeling Based On Wilco Albums, Caroline Pollard 2021 University of Mississippi

Use Of Linear Discriminant Analysis In Song Classification: Modeling Based On Wilco Albums, Caroline Pollard

Honors Theses

The study of music recommender algorithms is a relatively new area of study. Although these algorithms serve a variety of functions, they primarily help advertise and suggest music to users on music streaming services. This thesis explores the use of linear discriminant analysis in music categorization for the purpose of serving as a cheaper and simpler content-based recommender algorithm. The use of linear discriminant analysis was tested by creating lineardiscriminant functions that classify Wilco’s songs into their respective albums, specifically A.M., Yankee Hotel Foxtrot, and Sky Blue Sky. 4 sample songs were chosen from each album, and song ...


Markov Chains And Their Applications, Fariha Mahfuz 2021 University of Texas at Tyler

Markov Chains And Their Applications, Fariha Mahfuz

Math Theses

Markov chain is a stochastic model that is used to predict future events. Markov chain is relatively simple since it only requires the information of the present state to predict the future states. In this paper we will go over the basic concepts of Markov Chain and several of its applications including Google PageRank algorithm, weather prediction and gamblers ruin.

We examine on how the Google PageRank algorithm works efficiently to provide PageRank for a Google search result. We also show how can we use Markov chain to predict weather by creating a model from real life data.


Tournament And Non-Tournament Anglers Have Little Effect On A Largemouth Bass Population Compared To Natural Mortality, Andrea Sylvia, Stephen J. Dinsmore, Michael J. Weber 2021 Iowa State University

Tournament And Non-Tournament Anglers Have Little Effect On A Largemouth Bass Population Compared To Natural Mortality, Andrea Sylvia, Stephen J. Dinsmore, Michael J. Weber

Natural Resource Ecology and Management Publications

Popularity of bass Micropterus spp. catch and release and tournament angling during the past decade has resulted in increased potential for these activities to induce population level effects. Understanding capture rates and mortality sources relative to total population mortality is essential to focus of management. We conducted monthly electrofishing, solicited nontournament angler tag returns, and censused largemouth bass Micropterus salmoides tournaments at Brushy Creek Lake, IA, USA from April 2015 to June 2018. We used a multistate mark-recapture model to evaluate the effects of air temperature, water temperature, tournament bass per angler, and tournament initial mortality on non-tournament and tournament ...


Testing Identifying Assumptions In Bivariate Probit Models, Santiago Acerenza, Otávio Bartalotti, Desire Kedagni 2021 Iowa State University

Testing Identifying Assumptions In Bivariate Probit Models, Santiago Acerenza, Otávio Bartalotti, Desire Kedagni

Economics Working Papers

This paper focuses on the bivariate probit model's identifying
assumptions: joint normality of errors, instrument exogeneity, and relevance conditions. First, we develop novel sharp testable equalities that can detect all possible observable violations of the assumptions. Second, we propose an easy-to-implement testing procedure for the model's validity based on feasible testable implications using existing inference methods for intersection bounds. The test achieves correct empirical size for moderately sized samples and performs well in detecting violations of the conditions in Monte Carlo simulations. Finally, we provide researchers with a road map on what to do when the bivariate probit ...


Modelling The Impact Of Clot Fragmentation On The Microcirculation After Thrombectomy, Wahbi K. El-Bouri, Andrew MacGowan, Tamas I. Jozsa, Matthew J. Gounis, Stephen J. Payne 2021 University of Oxford

Modelling The Impact Of Clot Fragmentation On The Microcirculation After Thrombectomy, Wahbi K. El-Bouri, Andrew Macgowan, Tamas I. Jozsa, Matthew J. Gounis, Stephen J. Payne

Radiology Publications

Many ischaemic stroke patients who have a mechanical removal of their clot (thrombectomy) do not get reperfusion of tissue despite the thrombus being removed. One hypothesis for this 'no-reperfusion' phenomenon is micro-emboli fragmenting off the large clot during thrombectomy and occluding smaller blood vessels downstream of the clot location. This is impossible to observe in-vivo and so we here develop an in-silico model based on in-vitro experiments to model the effect of micro-emboli on brain tissue. Through in-vitro experiments we obtain, under a variety of clot consistencies and thrombectomy techniques, micro-emboli distributions post-thrombectomy. Blood flow through the microcirculation is modelled ...


Estimating The Size Of Georgia's Resident Canada Goose Population, Gregory D. Balkcom 2021 Georiga Department of Natrual Resources

Estimating The Size Of Georgia's Resident Canada Goose Population, Gregory D. Balkcom

Georgia Journal of Science

Canada geese (Branta canadensis) are an important waterfowl species in Georgia, and are hunted across the state. To meet management objectives, managers need to understand the impacts of hunting regulations on the population of interest. Therefore, reliable population estimates are necessary. Population size can be estimated by various methods, including aerial surveys, ground surveys, or population indices such as the Lincoln Estimator. I used annual estimates of resident Canada goose harvest in Georgia from the U.S. Fish and Wildlife Service’s Harvest Information Program along with banding and recovery data from the Bird Banding Laboratory in a bias-adjusted version ...


Gene Expression In Tonsils In Swine Following Infection With Porcine Reproductive And Respiratory Syndrome Virus, Qian Dong, Joan K. Lunney, Kyu-Sang Lim, Yet Nguyen, Andrew S. Hess, Hamid Beiki, Raymond R. R. Rowland, Kristen Walker, James M. Reecy, Christopher K. Tuggle, Jack C. M. Dekkers 2021 Iowa State University

Gene Expression In Tonsils In Swine Following Infection With Porcine Reproductive And Respiratory Syndrome Virus, Qian Dong, Joan K. Lunney, Kyu-Sang Lim, Yet Nguyen, Andrew S. Hess, Hamid Beiki, Raymond R. R. Rowland, Kristen Walker, James M. Reecy, Christopher K. Tuggle, Jack C. M. Dekkers

Animal Science Publications

Background: Porcine reproductive and respiratory syndrome (PRRS) is a threat to pig production worldwide. Our objective was to understand mechanisms of persistence of PRRS virus (PRRSV) in tonsil. Transcriptome data from tonsil samples collected at 42 days post infection (dpi) were generated by RNA-seq and NanoString on 51 pigs that were selected to contrast the two PRRSV isolates used, NVSL and KS06, high and low tonsil viral level at 42 dpi, and the favorable and unfavorable genotypes at a genetic marker (WUR) for the putative PRRSV resistance gene GBP5.

Results: The number of differentially expressed genes (DEGs) differed markedly between ...


Non-Adherence Tree Analysis (Nata)-An Adherence Improvement Framework: A Covid-19 Case Study, Ernest Edem Edifor, Regina Brown, Paul Smith, Rick Kossik 2021 Manchester Metropolitan University

Non-Adherence Tree Analysis (Nata)-An Adherence Improvement Framework: A Covid-19 Case Study, Ernest Edem Edifor, Regina Brown, Paul Smith, Rick Kossik

COVID-19 Publications by UMMS Authors

Poor medication adherence is a global phenomenon that has received a significant amount of research attention yet remains largely unsolved. Medication non-adherence can blur drug efficacy results in clinical trials, lead to substantial financial losses, increase the risk of relapse and hospitalisation, or lead to death. The most common methods of measuring adherence are post-treatment measures; that is, adherence is usually measured after the treatment has begun. What the authors are proposing in this multidisciplinary study is a new technique for predicting the factors that are likely to cause non-adherence before or during medication treatment, illustrated in the context of ...


Evaluation Of Individual And Ensemble Probabilistic Forecasts Of Covid-19 Mortality In The Us, Estee Y. Cramer, Velma K. Lopez, Jarad Niemi, Glover E. George, Jeffrey C. Cegan, Ian D. Dettwiller, William P. England, Matthew W. Farthing, Robert H. Hunter, Brandon Lafferty, Igor Linkov, Michael L. Mayo, Matthew D. Parno, Michael A. Rowland, Benjamin D. Trump, Lily Wang, Lei Gao, Zhiling Gu, Myungjin Kim, Yueying Wang, Jo W. Walker, Rachel B. Slayton, Michael Johansson, Matthew Biggerstaff, et al. 2021 University of Massachusetts

Evaluation Of Individual And Ensemble Probabilistic Forecasts Of Covid-19 Mortality In The Us, Estee Y. Cramer, Velma K. Lopez, Jarad Niemi, Glover E. George, Jeffrey C. Cegan, Ian D. Dettwiller, William P. England, Matthew W. Farthing, Robert H. Hunter, Brandon Lafferty, Igor Linkov, Michael L. Mayo, Matthew D. Parno, Michael A. Rowland, Benjamin D. Trump, Lily Wang, Lei Gao, Zhiling Gu, Myungjin Kim, Yueying Wang, Jo W. Walker, Rachel B. Slayton, Michael Johansson, Matthew Biggerstaff, Et Al.

Statistics Publications

Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models provide specific, quantitative, and evaluable predictions that inform short-term decisions such as healthcare staffing needs, school closures, and allocation of medical supplies. In 2020, the COVID-19 Forecast Hub (https://covid19forecasthub.org/) collected, disseminated, and synthesized hundreds of thousands of specific predictions from more than 50 different academic, industry, and independent research groups. This manuscript systematically evaluates 23 models that regularly submitted forecasts of ...


The Mean-Reverting 4/2 Stochastic Volatility Model: Properties And Financial Applications, Zhenxian Gong 2021 The University of Western Ontario

The Mean-Reverting 4/2 Stochastic Volatility Model: Properties And Financial Applications, Zhenxian Gong

Electronic Thesis and Dissertation Repository

Financial markets and instruments are continuously evolving, displaying new and more refined stylized facts. This requires regular reviews and empirical evaluations of advanced models. There is evidence in literature that supports stochastic volatility models over constant volatility models in capturing stylized facts such as "smile" and "skew" presented in implied volatility surfaces. In this thesis, we target commodity and volatility index markets, and develop a novel stochastic volatility model that incorporates mean-reverting property and 4/2 stochastic volatility process. Commodities and volatility indexes have been proved to be mean-reverting, which means their prices tend to revert to their long term ...


Regression Analyses Assessing The Impact Of Environmental Factors On Covid-19 Transmission And Mortality, El Hussain Shamsa, Kezhong Zhang 2021 Wayne State University

Regression Analyses Assessing The Impact Of Environmental Factors On Covid-19 Transmission And Mortality, El Hussain Shamsa, Kezhong Zhang

Medical Student Research Symposium

No abstract provided.


The Determinations Of Public Trust In The Government Of Egypt: An Empirical Study, Mohamed Elimam 2021 American University in Cairo

The Determinations Of Public Trust In The Government Of Egypt: An Empirical Study, Mohamed Elimam

Theses and Dissertations

Trust is a concept that is usually studied in the context of social interactions. At varying levels, we trust our families and friends, we trust strangers who share some traits with us and even trust institutions like banks with our savings and to handle our personal finances. By expansion, political trust, or the public's trust in government as a whole and as individual agencies. Trust in government forms a basis for the legitimacy. High levels of political trust facilitates the implementation of policies with more willing compliance from the public. This is more evident in situations like global and ...


Drivers Of English Syntactic Change In The Canadian Parliament, Liwen Hou, David Smith 2021 Northeastern University

Drivers Of English Syntactic Change In The Canadian Parliament, Liwen Hou, David Smith

Proceedings of the Society for Computation in Linguistics

Corpus linguists have long noted the "colloquialization'' of many genres of English. While the average decline in many features of formal speech is obvious in aggregate, we are better able to disentangle drivers of change by examining Canadian parliamentary speeches coded for characteristics of individual speakers across more than 100 years---much longer than previous studies of individuals' language change in a common environment. While many language changes proceed by cohort replacement and often originate with female speakers, the Canadian Hansard shows that most speakers employed increasingly colloquial language over their careers and that gender effects are mostly explained by the ...


Modeling Longitudinal Change In Cervical Length Across Pregnancy, Hope M. Wolf, Shawn J. Latendresse, Jerome F. Strauss III, Timothy P. York 2021 Virginia Commonwealth University

Modeling Longitudinal Change In Cervical Length Across Pregnancy, Hope M. Wolf, Shawn J. Latendresse, Jerome F. Strauss Iii, Timothy P. York

Graduate Research Posters

Introduction: A short cervix (cervical length < 25 mm) in the mid-trimester (18 to 24 weeks) of pregnancy is a powerful predictor of spontaneous preterm delivery (gestational age at delivery < 37 weeks). Although the biological mechanisms of cervical remodeling have been the subject of extensive investigation, very little is known about the rate of change in cervical length over the course of a pregnancy, or the extent to which rapid cervical shortening increases maternal risk for spontaneous preterm delivery.

Methods: A cohort of 5,160 unique women carrying 5,971 singleton pregnancies provided two or more measurements of cervical length during pregnancy. Cervical length was measured in millimeters using a transvaginal 12-3 MHz ultrasound endocavity probe (SuperSonic Imagine). Maternal characteristics, including relevant medical history and birth outcome data, were collected for each participant. Gestational age at delivery was measured from the first day of each woman’s last menstrual period and confirmed by ultrasound. Repeated measurements of cervical length during pregnancy were modeled as a longitudinal, multilevel growth curve in MPlus. A three-level ...


Projected Changes In Temperature And Precipitation Over The United States, Central America, And The Caribbean In Cmip6 Gcms, Mansour Almazroui, M. Nazrul Islam, Fahad Saeed, Sajjad Saeed, Muhammad Ismail, Muhammad Azhar Ehsan, Ismaila Diallo, Enda O’Brien, Moetasim Ashfaq, Daniel Martínez-Castro, Tereza Cavazos, Ruth Cerezo-Mota, Michael K. Tippett, William J. Gutowski Jr., Eric J. Alfaro, Hugo G. Hidalgo, Alejandro Vichot-Llano, Jayaka D. Campbell, Shahzad Kamil, Irfan Ur Rashid, Mouhamadou Bamba Sylla, Tannecia Stephenson, Michael Taylor, Mathew Barlow 2021 King Abdulaziz University

Projected Changes In Temperature And Precipitation Over The United States, Central America, And The Caribbean In Cmip6 Gcms, Mansour Almazroui, M. Nazrul Islam, Fahad Saeed, Sajjad Saeed, Muhammad Ismail, Muhammad Azhar Ehsan, Ismaila Diallo, Enda O’Brien, Moetasim Ashfaq, Daniel Martínez-Castro, Tereza Cavazos, Ruth Cerezo-Mota, Michael K. Tippett, William J. Gutowski Jr., Eric J. Alfaro, Hugo G. Hidalgo, Alejandro Vichot-Llano, Jayaka D. Campbell, Shahzad Kamil, Irfan Ur Rashid, Mouhamadou Bamba Sylla, Tannecia Stephenson, Michael Taylor, Mathew Barlow

Geological and Atmospheric Sciences Publications

The Coupled Model Intercomparison Project Phase 6 (CMIP6) dataset is used to examine projected changes in temperature and precipitation over the United States (U.S.), Central America and the Caribbean. The changes are computed using an ensemble of 31 models for three future time slices (2021–2040, 2041–2060, and 2080–2099) relative to the reference period (1995–2014) under three Shared Socioeconomic Pathways (SSPs; SSP1-2.6, SSP2-4.5, and SSP5-8.5). The CMIP6 ensemble reproduces the observed annual cycle and distribution of mean annual temperature and precipitation with biases between − 0.93 and 1.27 °C and − 37.90 ...


Joint Modeling Of Distances And Times In Point-Count Surveys, Adam Martin-Schwarze, Jarad Niemi, Philip Dixon 2021 University of Michigan

Joint Modeling Of Distances And Times In Point-Count Surveys, Adam Martin-Schwarze, Jarad Niemi, Philip Dixon

Statistics Publications

Removal and distance modeling are two common methods to adjust counts for imperfect detection in point-count surveys. Several recent articles have formulated models to combine them into a distance-removal framework. We observe that these models fall into two groups building from different assumptions about the joint distribution of observed distances and first times to detection. One approach assumes the joint distribution results from a Poisson process (PP). The other assumes an independent joint (IJ) distribution with its joint density being the product of its marginal densities. We compose an IJ+PP model that more flexibly models the joint distribution and ...


Hyperbolic Quadrature Method Of Moments For The One-Dimensional Kinetic Equation, Rodney O. Fox, Frédérique Laurent 2021 Iowa State University

Hyperbolic Quadrature Method Of Moments For The One-Dimensional Kinetic Equation, Rodney O. Fox, Frédérique Laurent

Chemical and Biological Engineering Publications

A solution is proposed to a longstanding open problem in kinetic theory, namely, 5 given any set of realizable velocity moments up to order 2n, a closure for the moment of order 2n+1 is 6 constructed for which the moment system found from the free-transport term in the one-dimensional 7 (1-D) kinetic equation is globally hyperbolic and in conservative form. In prior work, the hyperbolic 8 quadrature method of moments (HyQMOM) was introduced to close this moment system up to fourth 9 order (n ≤ 2). Here, HyQMOM is reformulated and extended to arbitrary even-order moments. The 10 HyQMOM closure ...


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