Peritoneal Fibrosarcomatous Mesothelioma In A Cat, 2017 Iowa State University
Peritoneal Fibrosarcomatous Mesothelioma In A Cat, Tammy M-J Heerkens, Jodi D. Smith, Leslie Fox, Jesse M. Hostetter
Primary tumors of serosal surfaces are uncommon in veterinary medicine. Mesothelial neoplasms can be benign or malignant, and are classified as predominantly epitheloid, mixed (biphasic), or fibrous (spindle cell, fibrosarcomatous), with fibrous mesotheliomas reported least in domestic species. A 9-year-old Domestic Shorthair cat presented on emergency with a brief history of weakness and lethargy. On presentation, the cat was semicomatose, hypothermic, and hypotensive with a markedly distended abdomen. Approximately 1 liter of serosanguineous fluid was removed via abdominocentesis. Diagnostic imaging and cytologic evaluation of fine-needle aspirates were suggestive of neoplasia, and the cat was subsequently euthanized. At necropsy, the omentum ...
Canine Emotions As Seen Through Human Social Cognition, 2017 University of Helsinki
Canine Emotions As Seen Through Human Social Cognition, Miiamaaria V. Kujala
Animal Sentience: An Interdisciplinary Journal on Animal Feeling
It is not possible to demonstrate that dogs (Canis familiaris) feel emotions, but the same is true for all other species, including our own. The issue must therefore be approached indirectly, using premises similar to those used with humans. Recent methodological advances in canine research reveal what dogs experience and what they derive from the emotions perceptible in others. Dogs attend to social cues, they respond appropriately to the valence of human and dog facial expressions and vocalizations of emotion, and their limbic reward regions respond to the odor of their caretakers. They behave differently according to the emotional situation ...
Identification Of Feline Tritrichomonas Foetus Surface Epitopes: Putative Targets For Development Of A Novel Diagnostic Test For Feline Trichomonosis, 2016 University of Tennessee - Knoxville
Identification Of Feline Tritrichomonas Foetus Surface Epitopes: Putative Targets For Development Of A Novel Diagnostic Test For Feline Trichomonosis, Emily Nissa Gould
BACKGROUND: Tritrichomonas foetus (T. foetus) is a flagellated protozoa that infects the distal ileum and proximal colon of domestic cats and also induces reproductive failure in cattle. Although feline trichomonosis is recognized to have a global prevalence of up to 30%, it still poses a diagnostic and therapeutic challenge to veterinarians; thus, there is a need for both improved diagnostics and therapeutics. Despite differing organ tropism between genotypes, evidence exists for conserved virulence factors between feline and bovine T. foetus. Two epitopes (1.15 and 1.17) of the bovine T. foetus glycosylated surface antigen 1.15-1.17 have been ...
Cinv Survey, 2016 Iowa State University
Cinv Survey, Lauren Hackbarth
Honors Projects and Posters
Introduction: Chemotherapy-induced nausea and vomiting (CINV) is a common side effect of chemotherapeutic treatment experienced by dogs that can lower quality of life and functionality. These symptoms are likewise found in people receiving chemotherapy; however, human oncology has well-established protocols for preventing these side effects, while veterinary medicine does not. The objective of this research is to establish a baseline regarding current standard of care to determine how veterinary specialists are managing CINV in dogs receiving chemotherapy.
Introduction: Chemotherapy-induced nausea and vomiting (CINV) is a common side effect of chemotherapeutic treatment experienced by dogs that can lower quality of life ...
Animal-Assisted Therapy For Military Veterans With Posttraumatic Stress Disorder: An Investigation On The Positive Effects Of Attachment And Affiliation Behaviors, 2016 Dominican University of California
Animal-Assisted Therapy For Military Veterans With Posttraumatic Stress Disorder: An Investigation On The Positive Effects Of Attachment And Affiliation Behaviors, Sara Miele
Scholarly & Creative Works Conference 2018
Posttraumatic stress disorder (PTSD) develops in people who have experienced a traumatic event (nimh.nih.gov, 2016). Because PTSD is a chronic disorder, it is associated with impaired quality of life (Stern et al., 2013). A specific population at high risk for developing PTSD is military veterans. It is estimated over half a million military veterans suffer from PTSD (Stern et al., 2013). Although there are psychological services and treatments for veterans, many do not seek help because fear of the negative stigma associated with mental illness (Lanning & Krenek, 2013). Recently, efforts have been made to implement veteran friendly treatment ...
Alterations Of The Ileal And Colonic Mucosal Microbiota In Canine Chronic Enteropathies, 2016 Iowa State University
Alterations Of The Ileal And Colonic Mucosal Microbiota In Canine Chronic Enteropathies, Eric Cassmann, Robin White, Todd Atherly, Chong Wang, Yaxuan Sun, Samir Khoda, Curtis L. Mosher, Mark R. Ackermann, Albert Jergens
Veterinary Clinical Sciences Publications
The intestinal microbiota is increasingly linked to the pathogenesis of chronic enteropathies (CE) in dogs. While imbalances in duodenal and fecal microbial communities have been associated with mucosal inflammation, relatively little is known about alterations in mucosal bacteria seen with CE involving the ileum and colon.
To investigate the composition and spatial organization of mucosal microbiota in dogs with CE and controls.
Tissue sections from endoscopic biopsies of the ileum and colon from 19 dogs with inflammatory bowel disease (IBD), 6 dogs with granulomatous colitis (GC), 12 dogs with intestinal neoplasia, and 15 controls were studied by ...
Meningeal Worm In Central Iowa Goat Herds, 2016 Iowa State University
Meningeal Worm In Central Iowa Goat Herds, Kelly Still Brooks
Animal Industry Report
Aberrant migration of the deer meningeal worm, Parelaphostrongylus tenuis, is a commonly recognized cause of neurologic disease in South American camelids but is less frequently considered in other small ruminant species. After an unusually cool and wet summer season, central Iowa goat herds serviced by Iowa State University’s Veterinary Field Services have been increasingly affected by P. tenuis, with clinical cases presenting as early as August. Most caprine cases present with progressive neurologic deficits, starting with hind-end weakness and ataxia which may lead to complete paresis and death. Both sporadic cases and herd outbreaks involving as much as 15 ...
Retinal Detachment Post-Phacoemulsification In Bichons Frises: A Retrospective Study Of 54 Dogs, 2016 University of Wisconsin-Madison
Retinal Detachment Post-Phacoemulsification In Bichons Frises: A Retrospective Study Of 54 Dogs, Silvia G. Pryor, Ellison Bentley, Gillian J. Mclellan, Elizabeth A. Giuliano, Rachel A. Allbaugh, Amy J. Rankin, Amber L. Labelle, Kevin A. Buhr
Veterinary Clinical Sciences Publications
Objective—To compare rates of retinal detachment (RD) post phacoemulsification in American Bichons Frises with and without prophylactic retinopexy.
Procedures—Medical records of 54 Bichons Frises undergoing phacoemulsification with or without prophylactic retinopexy between 2003–2013 in one or both eyes were reviewed from five Midwestern university veterinary teaching hospitals. Inclusion criteria were pre-operative ERG, at least 6 months of follow up post phacoemulsification, and absence of pre-existing RD as determined by ophthalmic examination and/or ultrasound. Statistical analyses used chi-squared and Wilcoxon rank-sum tests and Wilson confidence intervals with the p value
Results—Phacoemulsification was performed without retinopexy in ...
Clinical Study Of Canine Tear Lacritin As A Treatment For Dry Eye, 2016 James Madison University
Clinical Study Of Canine Tear Lacritin As A Treatment For Dry Eye, Katherine E. Kelly
Senior Honors Projects, 2010-current
Keratoconjunctivitis sicca (KCS), the deficiency of tears also known as dry eye, is a prevalent disease that affects both humans and canines. The current treatment for dye eye, cyclosporine (Restatis®), only provides temporary relief, is often associated with discomfort and is inconsistently effective. Lacritin is a naturally occurring tear glycoprotein secreted from the human and canine lacrimal glands. It has been shown that lacritin stimulates basal tearing in rabbits when applied topically. This study characterized the amount and form of lacritin found in the tears of dogs with healthy and dry eyes—information which may be applied to the development ...
Free-Roaming Dogs In Developing Countries: The Benefits Of Capture, Neuter, And Return Programs, 2015 Humane Society University
Free-Roaming Dogs In Developing Countries: The Benefits Of Capture, Neuter, And Return Programs, Jennifer Jackman, Andrew N. Rowan
Jennifer Jackman, Ph.D.
This chapter provides an overview of animal welfare and public health problems associated with free-roaming dog populations and strategies to resolve these problems. Placing CNR programs in the context of earlier dog and rabies control methods, the chapter explores CNR’s potential to overcome some of the shortcomings of earlier approaches and to improve animal welfare, reduce dog population growth, and prevent the spread of rabies and other canine-transmitted diseases. Constraints and current debates on current implementation of CNR programs are also examined.
Tear Volume, Turnover Rate, And Flow Rate In Ophthalmologically Normal Horses, 2015 University of Tennessee - Knoxville
Tear Volume, Turnover Rate, And Flow Rate In Ophthalmologically Normal Horses, Thomas Chen, Daniel Ward
Thomas Chen DVM, DACVO
No abstract provided.
Aflatoxicosis In Dogs And Dealing With Suspected Contaminated Commercial Foods, 2015 University of Tennessee - Knoxville
Aflatoxicosis In Dogs And Dealing With Suspected Contaminated Commercial Foods, Katherine Stenske, J Smith, Shelley Newman, L Newman, Claudia Kirk
No abstract provided.
No abstract provided.
Preparatory Work For The Future Development Of Scientific Opinions On Animal Health, 2015 Iowa State University
Preparatory Work For The Future Development Of Scientific Opinions On Animal Health, Annette M. O'Connor, Rungano Stan Dzikamunhenga, D. Wolfe, Jan M. Sargeant, J. Glanville, J Wood
Veterinary Diagnostic and Production Animal Medicine Reports
This final report summarizes the results of two reviews and a scoping study related to Canine leishmaniosis (CanL). Three objectives were addressed in this project. Objective 1 was to summarize relative sensitivity and specificity estimates of assays used to detect infection in dogs with Leishmania infantum in studies of naïve dogs in areas where Leishmania infantum infection is endemic. Objective 2 was to summarize data available to estimate the prevalence of parasitological cure (failure to detect organism) after a 12-month follow-up period in animals treated with meglumine antimoniate, miltefosine, and allopurinol or combinations of these drugs for canine leishmaniosis. Objective ...
Cats, Cancer And Comparative Oncology, 2014 University of Minnesota - Twin Cities
Cats, Cancer And Comparative Oncology, Claire Cannon
No abstract provided.
Alkaline Phosphatase Is A Sensitive Cytochemical Marker For The Diagnosis Of Acute Myelomonocytic And Monocytic Leukemia In The Dog, Stokol Tracy, Deanna Schaefer, Belcher Nicole, Shuman Martha, Dong L
BACKGROUND: Immunophenotyping has replaced cytochemical staining as the preferred technique for classifying acute leukemia. However, some acute myeloid leukemias (AML) lack lineage-associated markers. In our experience, alkaline phosphatase (ALP) is expressed in immature canine monocytes. We hypothesized that ALP is a useful marker for monocytic AML.
OBJECTIVES: The objective was to compare ALP expression in neoplastic cells from dogs with lymphoma, chronic lymphocytic leukemia (CLL), acute lymphoid leukemia (ALL), and AML.
METHODS: Alkaline phosphatase results were retrieved from medical records of dogs with acute leukemia. Smears from dogs with lymphoma or leukemia were also prospectively stained for ALP activity. CLL ...
Clinical Signs, Treatment, And Outcome In Cats With Myeloma-Related Disorder Receiving Systemic Therapy, 2014 University of Minnesota - Twin Cities
Clinical Signs, Treatment, And Outcome In Cats With Myeloma-Related Disorder Receiving Systemic Therapy, Claire Cannon
Myeloma-related disorder (MRD) is an uncommon disease in cats, for which there is no established standard of care. In this retrospective study, we evaluated presentation, response to treatment, and toxicity in cats with MRD receiving systemic treatment. Previously reported prognostic factors were evaluated for their impact on survival in cats receiving chemotherapy. Of fifteen cases identified, thirteen received melphalan or cyclophosphamide +/- corticosteroids as first-line therapy. Chlorambucil was commonly used as rescue therapy in cats with progressive disease, or in cases of chemotherapy-related toxicity with first line agents. Overall response rates were 71% and 83% for melphalan- and cyclophosphamide-treated cats, respectively ...
The Utility Of Reticulocyte Indices In Distinguishing Iron Deficiency Anemia From Anemia Of Inflammatory Disease, Portosystemic Shunting, And Breed-Associated Microcytosis In Dogs, 2014 University of Tennessee - Knoxville
The Utility Of Reticulocyte Indices In Distinguishing Iron Deficiency Anemia From Anemia Of Inflammatory Disease, Portosystemic Shunting, And Breed-Associated Microcytosis In Dogs, Deanna Schaefer, Tracy Stokol
BACKGROUND: Indices of reticulocyte cell size and hemoglobin content show promise for diagnosing iron deficiency (FeDef), but have not been evaluated in other causes of canine anemia or microcytosis.
OBJECTIVES: The aims of this study were to establish reference intervals (RI) for reticulocyte indices in dogs, and to compare results from dogs with FeDef anemia to dogs with 3 conditions that may mimic FeDef on hematologic and biochemical testing, including anemia of inflammatory disease (AID), portosystemic shunting (PSS), or breed-associated microcytosis (BAM).
METHODS: Reticulocyte indices were measured using the ADVIA 2120. Reference intervals were determined prospectively in 122 healthy dogs ...
The Effect Of Il-6 On Satellite Cell Activity In Tumor Bearing Mice, 2014 Selected Works
The Effect Of Il-6 On Satellite Cell Activity In Tumor Bearing Mice
Cancer cachexia results in severe muscle atrophy and can greatly hinder the quality of life and chances of survival for the afflicted individual. In studies where cachexia-induced muscle atrophy is inhibited, survival is prolonged. The activity of satellite cells, the muscle progenitor cells that incorporate into muscle fibers to cause hypertrophy, is the focus of this study. It was hypothesized that mRNA expression of Pax7, MyoD, FoxO1, FoxO3a, and FoxO4 would be altered in injured muscle in TB animals, and this would be attenuated by inhibition of interleukin (IL)-6 signaling. To test this hypothesis, tumor bearing (TB) and control ...
Evaluation Of A Combination Chemotherapy Protocol Including Lomustine And Doxorubicin In Canine Histiocytic Sarcoma, 2014 University of Tennessee - Knoxville
Evaluation Of A Combination Chemotherapy Protocol Including Lomustine And Doxorubicin In Canine Histiocytic Sarcoma, Claire Cannon, Antonella Borgatti, Michael Henson, Brian Husbands
No abstract provided.