Science and Technology Policy Commons^™

Current Status And Prospect Of Industrial Filamentous Fungi In Biomanufacturing, Zhiqiang Du, Ping Men, Yu Zhou, Xuan Zhang, Xuenian Huang, Xuefeng Lyu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Filamentous fungi, a critical class of industrial microorganisms pivotal to the biomanufacturing industry, has extensive applications in various fields such as pharmaceuticals, food, agriculture, and chemical materials, which are playing a vital role in human life. Recently, innovations in synthetic biology have further driven the application of industrial filamentous fungi in biomanufacturing, highlighting their critical role in this field. This article presents a comprehensive review of the recent progress in the field, covering the latest developments in genetic modification techniques for industrial filamentous fungi, successful cases of rational strain improvement strategies aimed to enhance the quality and efficiency of current …

Efficient Discovery And Industrialized Manufacture Of Terpenoids, Haoming Chi, Liying Er, Tiangang Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Terpenoids, a class of chemical entities with diverse biological activities in nature, demonstrate significant potential for applications in fields such as drug discovery, flavor industry, and agriculture. However, traditional methods face challenges, including inefficiency and high costs, in the discovery and industrialization of terpenoids. The rapid development of synthetic biology, genomics, artificial intelligence, and automation provides new opportunities for efficient terpenoid discovery and industrialization. This study comprehensively analyzes how these technologies synergistically contribute to the discovery, optimization, and large-scale production of terpenoids, and summarizes the current high-yield situations of terpenoids. The aim is to propose innovative strategies to accelerate technological …

Microsphere Core Technology Boosts Innovation Of Biopharmaceutical Industry Chain, Jie Wu, Weiqing Zhou, Lan Zhao, Guanghui Ma

Bulletin of Chinese Academy of Sciences (Chinese Version)

Advancements in life science and biotechnology have boosted the evolution of the biopharmaceutical industry with the continual emergence of biomedical products for disease prevention, diagnosis, and treatment. Microspheres, as crucial functional materials, play a significant role in the discovery, preparation, separation, and delivery of biological drugs due to their flexible size, morphology, structure, and function. This study reviews recent significant advancements in microspheres and their applications in cell culture, chromatographic separation, drug delivery, and as vaccine adjuvants. Additionally, it proposes future trends for the development of microspheres.

Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Biomanufacturing, an emerging production method, is becoming a significant trend in global economic development and has garnered widespread international attention. Platform facilities are vital to the biomanufacturing industry’s development, serving as both the foundation for technological innovation and the bridge between research outcomes and practical applications. This study analyzes three key types of platform facilities and their operational mechanisms: technology innovation platforms (exemplified by the U.S. Agile BioFoundry), pilot-scale platforms (represented by European Bio Base Europe Pilot Plant), and industry incubation platforms (illustrated by the UK SynbiCITE). Drawing from these successful examples and examining China’s current platform infrastructure, this paper …

Research On Innovative Development Path And Policy Guarantee Of China’S Synthetic Biology Industry, Hongjun Geng, Chang Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Synthetic biology is hailed as the third revolution in life sciences after the discovery of the DNA double helix structure and genomic technology, and is the core driving force for the leapfrog development of next-generation biomanufacturing and the future bioeconomy, opening up an opportunity window for the reshaping of the global manufacturing map. How to strategically position the synthesis biology industry and seize the strategic high ground in the industry is a core topic of interest for global science and technology powers and manufacturing powers. Based on the identification of problems in the development of China’s synthesis biology industry, this …

Scientific Approach To Building A Highland Of Ecological Civilization In Xizang Of China, Xiaodan Wang, Jianxin Zhang, Da Wei, Hui Zhao, Jiangtao Hong, Yuling Liang, Yahui Qi, Zhengrong Yuan

Bulletin of Chinese Academy of Sciences (Chinese Version)

Xizang, which plays an important barrier role in maintaining national ecological security, is a unique region that ensures China’s sustainable development and leads the construction of national ecological civilization. The Seventh Central Conference on the Work of Xizang has set clear goals and specific requirements for building an ecological civilization highland on the Qinghai-Xizang Plateau, which were identified as a new mission and task of Xizang government for environmental protection and sustainable development in the new era. Based on the previous research achievements about national ecological security barrier, this work further carried out the systematic study of ecological civilization highland …

Internal Logic And Policy Recommendations Of Big Data To Support High-Quality Development Of Modern Agricultural Industry, Yingming Li, Zitong Wang, Mingyue Wang, Shiyi Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Clarifying the internal logic of big data to support modern agricultural production is helpful to cultivate and develop new quality productive forces in agriculture. From the perspective of economics, this study proposes that the role of big data in modern agricultural production is mainly reflected in two levels. Firstly, it improves the total factor productivity of the traditional agricultural production function. Secondly, it changes the factor endowment structure of agricultural production and forms a new agricultural production function. Based on these, the realization form of big data to support modern agricultural production can be summarized as improving the efficiency of …

Development And Utilization Of Mineral Resources In The Arctic And China’S Strategic Countermeasures, Yina Su

Bulletin of Chinese Academy of Sciences (Chinese Version)

There are abundant strategic mineral resources as oil, gas, iron ore, copper, and nickel in the Arctic region. If the Arctic routes can be opened in the future, they will become another important transportation channels connecting the Pacific and Atlantic Oceans, following the Panama Canal and the Suez Canal, which may reshape the world’s maritime trade and transportation pattern. With the development of science and technology, increase in mineral resources consumption and changes in the international environment, the strategic position of the Arctic region is increasingly elevated, and the United States, Russia and some other countries of the European Union …

Redesign And De Novo Design Of Circular Blue Bioindustry, Wei Zhang, Shufeng Zhang, Hantao Zhou, Minhan Dai

Bulletin of Chinese Academy of Sciences (Chinese Version)

The future marine bioindustry, which features advanced green intelligent biomanufacturing and high-value marine bioproducts, is a strategically emerging marine industry. This study proposes a new industrial development model for the circular blue bioindustry, founded on simultaneously optimizing the sustainable utilization of marine bioresources and protecting the ecological environment. Through in-depth analysis of the current situation, challenges, and potential development opportunities of the global and Chinese marine bioindustries underpinning sustainable development, theoretical framework, approaches and implementation pathways have been established to redesign the existing marine bioindustry and de novo design of the emerging marine bioindustry. Future key development priorities are suggested …

Analysis On Development Status And Characteristics Of Non-Governmental Bio-Safety And Bio-Security Think Tanks In The United States, Wenbing Ma, Qiang Song, Lei Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

At present, the complexity of bio-safety governance is becoming increasingly prominent, and complex issues such as security and development in the bio-economy, preparedness and response to infectious disease pandemics, the interweaving and integration of bio-security and other security factors, and the integration of scientific and technological factors and security factors urgently require think tanks to conduct systematic, comprehensive and forward-looking assessments and provide professional solutions. Rooted in the relatively mature experience in the construction of think tanks in the United States, a number of bio-safety and bio-security think tanks with greater influence have been developed, which have acted as an …

Policy Overview (December, 2024)

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Outstanding Articles In 2023 Of Journal Of Chinese Academy Of Sciences

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Progress Toward Gender Equality In Research & Innovation - 2024 Review, Nicoline Van Der Linden, Guillaume Roberge, Dmitrii Malkov, Alexandre Bédard-Vallée, David Campbell, Elisabeth Browning, Henrique Pinheiro, Stacey Tobin, Thomas Collins, Tina Zdawcyzk, Yunxiaoxiao Zhang

Public Reports

In this report, we explore the progress made over the past two decades toward achieving equal participation by women in research and innovation. By contributing to a greater understanding of the current landscape, this report intends to illuminate pathways forward, inform policymaking and contribute to the pursuit of gender diversity and equal opportunities in the research workforce.

Deterring The Digital Dragon, Bryn Lacey

Theses

Australia’s 21st century has been heavily influenced by a growing number of cyber incidents ranging from individuals causing extraordinary damage to state-based attacks from adversary states such as China. Focusing on state actors in the cyber domain, this thesis investigates Martin Libicki’s cyber-deterrence framework, with a specific emphasis on the employment of deterrence by punishment, and applies this concept to the case study of the relationship between Australia and China.

In recent years, Australia has been consistently targeted by sophisticated state-based cyber actors and the Australian Government has appeared increasingly prepared to publicly criticise Beijing as a key security challenge. …

Police Flight Oversight: Lapd Drone As First Responder Implementation, Nathaniel Worley

CMC Senior Theses

This thesis explores the feasibility of implementing a Drone as First Responder (DFR) program within the Los Angeles Police Department (LAPD), analyzing the operational, social, and financial implications compared to traditional police helicopter usage. The thesis investigates helicopter flight patterns, demographic correlations, and the potential for drones to provide a less invasive and more cost-effective aerial support system. Key findings include the use of incorrect identifying hex codes by LAPD helicopters, suggesting potential transparency issues in aerial operations. The thesis recommends DFR due to substantial cost savings and enhanced surveillance transparency and asserts that a DFR program can mitigate negative …

A Review Of Emerging Sensor Technologies For Tank Inspection: A Focus On Lidar And Hyperspectral Imaging And Their Automation And Deployment, Sergio Pallas Enguita, Chung-Hao Chen, Samuel Kovacic

Electrical & Computer Engineering Faculty Publications

This paper reviews various sensor technologies for tank inspection, focusing on Light Detection and Ranging (LiDAR) and Hyperspectral Imaging (HSI) as advanced solutions for corrosion detection. These technologies are evaluated alongside traditional methods such as ultrasonic, electromagnetic, and thermographic inspections. This review highlights their potential to enhance inspection accuracy, reduce the limitations of manual inspection, and support integrated data analysis for comprehensive asset management. Additionally, this paper proposes a pathway for automating these techniques to streamline inspection processes and improve implementation in practical applications.

Chinese Fintech Goes Global: Political Challenges And Business Strategies, Yujia He

Patterson School of Diplomacy and International Commerce Faculty Publications

Fintech (the application of digital technology to financial services) has witnessed unprecedented growth, bringing significant implications for the financial system and sustainable development.1 The Financial Stability Board, an international body that monitors and makes recommendations about the global financial system, defines fintech as “technologically enabled financial innovation that could result in new business models, applications, processes, or products with an associated material effect on financial markets and institutions and the provision of financial services.”2 The use of technology in finance is certainly not new—consider the growth of electronic banking and high-frequency trading in the early 2000s. In the past two …

Silence Is Not Golden: Exploring The Trade-Offs Between Transparency And Burden In Dirs Reporting, Katie Nelson

Murray State Theses and Dissertations

This study explores the United States federal government's Disaster Information Reporting System (DIRS), which is an instrument that is used during emergencies to gather information on what five communication avenues are not actively working at the time of the emergency or during the recovery process. The synthesis provides a framework for characteristics that cite the necessities for this study on DIRS. Examining DIRS will help us understand its strengths, limitations, and potential improvements. Evaluating the details of historical and global research on emergency communications are gathered. The analysis provides insights into DIRS's past, present, and future. Bring to light future …

Proof Of Principle For A Self-Governing Prediction And Forecasting Reward Algorithm, Jose Osvaldo Gonzalez-Hernandez, Jonathan Marino, Ted Rogers, Brandon Velasco

Physics Faculty Publications

We use Monte Carlo techniques to simulate an organized prediction competition between a group of scientific experts acting under the influence of a "self-governing" prediction reward algorithm. Our aim is to illustrate the advantages of a specific type of reward distribution rule that is designed to address some of the limitations of traditional forecast scoring rules. The primary extension of this algorithm as compared with standard forecast scoring is that it incorporates measures of both group consensus and question relevance directly into the reward distribution algorithm. Our model of the prediction competition includes parameters that control both the level of …

Towards Trust And Reputation As A Service In Society 5.0, Stephan Olariu, Ravi Mukkamala, Meshari Aljohani

Computer Science Faculty Publications

Our paper was inspired by the recent Society 5.0 initiative of the Japanese Government which seeks to create a sustainable human-centric society by putting to work recent advances in technology. One of the key challenges in implementing Society 5.0 is providing trusted and secure services for everyone to use. Motivated by this challenge, this paper makes three contributions that we summarize as follows: Our first main contribution is to propose a novel blockchain and smart contract-based trust and reputation service design to reduce the uncertainty associated with buyer feedback in marketplaces that we expect to see in Society 5.0. Our …