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Disentangling Accelerated Cognitive Decline From The Normal Aging Process And Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach, Yulin Dai, Yu-Chun Hsu, Brisa S Fernandes, Kai Zhang, Xiaoyang Li, Nitesh Enduru, Andi Liu, Astrid M Manuel, Xiaoqian Jiang, Zhongming Zhao, Alzheimer’s Disease Neuroimaging Initiative 2024 The Texas Medical Center Library

Disentangling Accelerated Cognitive Decline From The Normal Aging Process And Unraveling Its Genetic Components: A Neuroimaging-Based Deep Learning Approach, Yulin Dai, Yu-Chun Hsu, Brisa S Fernandes, Kai Zhang, Xiaoyang Li, Nitesh Enduru, Andi Liu, Astrid M Manuel, Xiaoqian Jiang, Zhongming Zhao, Alzheimer’S Disease Neuroimaging Initiative

Faculty, Staff and Student Publications

BACKGROUND: The progressive cognitive decline, an integral component of Alzheimer's disease (AD), unfolds in tandem with the natural aging process. Neuroimaging features have demonstrated the capacity to distinguish cognitive decline changes stemming from typical brain aging and AD between different chronological points.

OBJECTIVE: To disentangle the normal aging effect from the AD-related accelerated cognitive decline and unravel its genetic components using a neuroimaging-based deep learning approach.

METHODS: We developed a deep-learning framework based on a dual-loss Siamese ResNet network to extract fine-grained information from the longitudinal structural magnetic resonance imaging (MRI) data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) study. …


Does Attention Control Mediate The Negative Effects Online Usage Exerts On College Students' Gpa, Carolina Rodriguez 2024 University of Central Florida

Does Attention Control Mediate The Negative Effects Online Usage Exerts On College Students' Gpa, Carolina Rodriguez

Honors Undergraduate Theses

Online media, especially social media, is a continuously growing area of research which has raised questions about its impacts on academic outcomes. Many previous studies have established a negative relation between social media use and academic performance; however, the mechanism behind this finding is still unknown. The present study investigated whether level of attention control mediates the relation between an individual’s propensity for online usage and grade point average (GPA). Undergraduate students at the University of Central Florida (N=226) were recruited for this study, and their levels of online vigilance and attention control were measured. College GPA was self-reported by …


Reporting On Un Security Council: Decoding Media Bias, Alessandra Loiero 2024 CUNY City College

Reporting On Un Security Council: Decoding Media Bias, Alessandra Loiero

Dissertations and Theses

This thesis explores Western media's representation of the United Nations (UN), focusing on the Security Council's role in global conflict resolution. It examines how UN-accredited correspondents perceive the effectiveness of the Security Council, particularly when the body faces deadlock. The study employs text analysis techniques to identify biases and perceptions in media coverage, using The New York Times' reporting on the Ukraine conflict as a case study. It illuminates framing effects in journalistic narratives, revealing how journalists subtly interject their views when reporting, often revealing unrealistic expectations and shedding light on the limitations of the UN's mandate or its inability …


Exploring Spatial Operations Of Distractor Suppression In The Sense Of Touch, Nicole A. Serino 2024 CUNY City College

Exploring Spatial Operations Of Distractor Suppression In The Sense Of Touch, Nicole A. Serino

Dissertations and Theses

The ability to select sensory information in our environment is key to facilitating goal-directed actions. Sensory selection mechanisms are prevalent in all sensory modalities, and can be implemented by enhancing information at the relevant location and/or suppressing neural information outside the focus of attention (a mechanism known as distractor suppression). Although we have a decent understanding of how the brain enhances information within the focus of attention, less is known about the mechanisms that mediate suppression of distractors, especially in sensory modalities outside vision. In this study, we conducted a series of behavioral experiments to investigate the spatial flexibility of …


Aromatherapies And Stress: An Examination Of Saliva Sclarea In Acute Stress Conditions, Emily J. Van Gundy 2024 Missouri State University

Aromatherapies And Stress: An Examination Of Saliva Sclarea In Acute Stress Conditions, Emily J. Van Gundy

Graduate Theses/Dissertations

The use of essential oils as an alternative medicine in the United States is becoming increasingly popular as more accreditation is given to its therapeutic values. With this increase in use, we must continue to examine the uses of essential oils, including associated risks. One unavoidable aspect of life is stress, both acute and chronic. This study aims to better our understanding of the stress-reducing properties of the essential oil clary sage (salvia sclarea) after an experimentally induced acute stress experience. The Trier Social Stress Test was used to elicit an acute stress response. Participants were given the scent of …


Circulating Sphingolipids In Relation To Cognitive Decline And Incident Dementia: The Cardiovascular Health Study, Kristine F Moseholm, Héléne T Cronjé, Manja Koch, Annette L Fitzpatrick, Oscar L Lopez, Marcia C de Oliveira Otto, W T Longstreth, Andrew N Hoofnagle, Kenneth J Mukamal, Rozenn N Lemaitre, Majken K Jensen 2024 The Texas Medical Center Library

Circulating Sphingolipids In Relation To Cognitive Decline And Incident Dementia: The Cardiovascular Health Study, Kristine F Moseholm, Héléne T Cronjé, Manja Koch, Annette L Fitzpatrick, Oscar L Lopez, Marcia C De Oliveira Otto, W T Longstreth, Andrew N Hoofnagle, Kenneth J Mukamal, Rozenn N Lemaitre, Majken K Jensen

Faculty, Staff and Student Publications

INTRODUCTION: Whether circulating levels of sphingolipids are prospectively associated with cognitive decline and dementia risk is uncertain.

METHODS: We measured 14 sphingolipid species in plasma samples from 4488 participants (mean age 76.2 years; 40% male; and 25% apolipoprotein E (

RESULTS: Higher plasma levels of sphingomyelin-d18:1/16:0 (SM-16) were associated with a faster cognitive decline measured with 3MSE, in contrast, higher levels of sphingomyelin-d18:1/22:0 (SM-22) were associated with slower decline in cognition measured with DSST. In Cox regression, higher levels of SM-16 (hazard ration [HR] = 1.24 [95% confidence interval [CI]: 1.08-1.44]) and ceramide-d18:1/16:0 (Cer-16) (HR = 1.26 [95% CI: 1.10-1.45]) …


The Development Of An Interactive Multimedia E-Learning Module For Functional Cognition, McKenzie R. Behrendt, Stacy Smallfield 2024 University of Nebraska Medical Center

The Development Of An Interactive Multimedia E-Learning Module For Functional Cognition, Mckenzie R. Behrendt, Stacy Smallfield

Journal of Occupational Therapy Education

The rise in technology, social media, and video has led to the desire for short, interactive, and visually appealing instructional materials. Modern learners want flexibility, repeatability, accessibility, and low-stakes knowledge checks. A multimedia e-learning module may meet the learner’s desires. This article describes the conception, development, and implementation of a free, interactive, multimedia e-learning module designed to enhance understanding and application of occupational therapy (OT) theoretical approaches to address functional cognition. We discuss the considerations for choosing a multimedia e-learning module as an instructional tool, drawing from existing research demonstrating its effectiveness. Particularly, a multimedia e-learning module potentially benefits addressing …


Facilitating Thought Progression To Reduce Depressive Symptoms: Randomized Controlled Trial, Shai-Lee Yatziv, Paola Pedrelli, Shira Baror, Sydney Ann DeCaro, Noam Shachar, Bar Sofer, Sunday Hull, Joshua Curtiss, Moshe Bar 2024 The Leslie and Susan Gonda Brain Science Center

Facilitating Thought Progression To Reduce Depressive Symptoms: Randomized Controlled Trial, Shai-Lee Yatziv, Paola Pedrelli, Shira Baror, Sydney Ann Decaro, Noam Shachar, Bar Sofer, Sunday Hull, Joshua Curtiss, Moshe Bar

Psychology Faculty Publications

Background:

The constant rise in the prevalence of major depressive disorder calls for new, effective, and accessible interventions that can rapidly and effectively reach a wide range of audiences. Recent developments in the digital health domain suggest that dedicated online platforms may potentially address this gap. Focusing on targeting ruminative thought, a major symptomatic hallmark of depression, in this study we hypothesized that delivering a digital health-based intervention designed to systematically facilitate thought progression would substantially alleviate depression.

Objective:

The study aims to investigate the efficacy of a novel digital intervention on the reduction of depressive symptoms. This intervention was …


Factors That Contribute To Perceptions Of Police-Civilian Interactions, Shelby Wynne 2024 University of Kentucky

Factors That Contribute To Perceptions Of Police-Civilian Interactions, Shelby Wynne

Theses and Dissertations--Psychology

Perceptions of police-civilian interactions have been found to be impacted by the perspective in which they are viewed, with first-person perspectives eliciting negative perceptions of civilians and positive perceptions of police. However, the nature of the relationship between race and camera-perspective has not been fully explored. Black people are more likely to harmed by police at a disproportionate rate compared to White people, and consequently, have more negative perceptions of police. Three studies investigated what factors informed perceptions of police encounters, particularly when camera perspectives differed. Results showed partial support for my prediction that Black people are as not susceptible …


Exposure To Low (10 Cgy) Doses Of ⁴He Ions Leads To An Apparent Increase In Risk Taking Propensity In Female Rats, Nina Li, Simran Phuyal, Elliot Smits, Faith E. Reid, Ella N. Tamgue, Paola Alvarado Arriaga, Richard A. Britten 2024 Macon & Joan Brock Virginia Health Sciences at Old Dominion University

Exposure To Low (10 Cgy) Doses Of ⁴He Ions Leads To An Apparent Increase In Risk Taking Propensity In Female Rats, Nina Li, Simran Phuyal, Elliot Smits, Faith E. Reid, Ella N. Tamgue, Paola Alvarado Arriaga, Richard A. Britten

Department of Medicine Faculty Publications

The planned missions to the Moon and Mars will present more significant health challenges to astronauts compared to low earth orbit missions. During deep space missions, astronauts will be constantly exposed to Space radiation (SR). Multiple rodent studies suggest that < 25 cGy of SR impairs performance in executive functions, which play a key role in advanced cognitive processes, but also regulate response inhibition and impulse control. There is the possibility that SR exposure may exacerbate aberrant behaviors evoked by psychological stress related to exposure to isolated and confined (ICE) hostile environment or independently induce additional aberrant behaviors. This study has determined that female Wistar rats exposed to 10 cGy of 250 MeV/n He had an increased risk taking propensity (RTP)\compared to shams. The increased RTP of the He-exposed rats was associated with significantly increased reaction times during the trials, suggesting a SR-induced loss of processing speed. The response times of the He-exposed rats were even further reduced in trials that immediately followed a loss, raising the possibility that conflict and interference avoidance may be impaired after SR exposure. Whether these findings occur following other types of SR exposure, and/or in male rats remains to be determined.


Target Selection And Enhancement During Attentional Tracking, Marvin R. Maechler 2024 Dartmouth College

Target Selection And Enhancement During Attentional Tracking, Marvin R. Maechler

Dartmouth College Ph.D Dissertations

At any waking moment, we are bombarded with more sensory information than we can fully process. Attention is necessary to deal with the dynamic world we live in. One fundamental function of vision and attention is to keep track of moving objects, but what are the targets of attention during tracking?

One of the first theories of attentional tracking predicted that targets would be selected at early processing stages. By employing the double-drift illusion, which dissociates physical and perceived positions of moving objects, we investigated which of these positions is selected for tracking. Contrary to earlier theories and in line …


Understaning Low Vision Graphical Perception Of Bar Charts, Yash Prakash, Akshay Kolgar Nayak, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok 2024 Old Dominion University

Understaning Low Vision Graphical Perception Of Bar Charts, Yash Prakash, Akshay Kolgar Nayak, Sampath Jayarathna, Hae-Na Lee, Vikas Ashok

Computer Science Faculty Publications

Bar charts are widely used for their simplicity in data representation, prompting numerous studies to explore and model how users interact with and perceive bar chart information. However, these studies have predominantly focused on sighted users, with a few also targeting blind screen-reader users, whereas the graphical perception of low-vision screen magnifier users is still an uncharted research territory. We fill this knowledge gap in this paper by designing four experiments for a laboratory study with 25 low-vision participants to examine their graphical perception while interacting with bar charts. For our investigation, we built a custom screen magnifier-based logger that …


Leveraging Instagram To Enhance Self-Esteem: A Self-Affirmative Intervention Study And Multilevel Mediation Analysis, Shuna Shiann KHOO, Hwajin YANG, Wei Xing TOH 2024 Singapore Management University

Leveraging Instagram To Enhance Self-Esteem: A Self-Affirmative Intervention Study And Multilevel Mediation Analysis, Shuna Shiann Khoo, Hwajin Yang, Wei Xing Toh

Research Collection School of Social Sciences

Although studies have consistently indicated that heavier use of social networking sites (SNS) perpetuates poorer self-esteem outcomes, no study has examined potential intervention methods that can yield positive effects from SNS use. We hypothesized that viewing one's Instagram profile would have self-affirmative effects on self-perception because the profile typically showcases curated instrumental positive aspects of self. Furthermore, these self-affirmative effects would indirectly improve state self-esteem via enhanced clarity of self-concept. To test our hypothesis, we designed an experimental intervention study where one group viewed their Instagram profile regularly, while another group viewed a neutral abstract art profile. Using multilevel latent …


Re-Globalizing Yorkville: The Languages On Shop Signs In A Non-Migrant Neighborhood, Lisabeth G. Dashman 2024 University at Albany, State University of New York

Re-Globalizing Yorkville: The Languages On Shop Signs In A Non-Migrant Neighborhood, Lisabeth G. Dashman

Electronic Theses & Dissertations (2024 - present)

The term “linguistic landscape” is used to describe the usage and placement of language in public places of a specific geographic area, such as on buildings, street names, pedestrian notices, vehicular warnings, and advertising billboards. Studies of a space’s linguistic landscape typically involve an accounting and analysis of the visible signs and/or the presentation of bystanders’ or researchers’ thoughts and observations. This study instead probes the intentions of the sign creators: the owners of the façade sign and the business it advertises. The façade sign, often called the shop sign, is frequently the first image for a business that a …


Is Chunking Multimodal?: Music Reading Expertise Effects On Eye Movements During A Cross-Modal Visual Search Paradigm, Nicole Arco 2024 University at Albany, State University of New York

Is Chunking Multimodal?: Music Reading Expertise Effects On Eye Movements During A Cross-Modal Visual Search Paradigm, Nicole Arco

Electronic Theses & Dissertations (2024 - present)

Experts show performance advantages during visual search due to their extensive experience with domain-specific stimuli. Experts form memory representations for meaningful visual patterns, called chunks, that group together multiple chess features. Prior work suggests that the ability for experts to precisely encode a search template facilitates visual search performance (e.g. Hout & Goldinger, 2015). In music, expert musicians might also form chunks (see e.g., Maturi & Sheridan, 2020), although it is unclear what constitutes a chunk in music. The current study addressed the possibility that chunks are multimodal by introducing a new auditory-visual cross-modal version of the visual search paradigm …


Investigating The Effect Of Sign-Tracking On Attention And Perceptual Inference, Maria C. Potts 2024 West Virginia University

Investigating The Effect Of Sign-Tracking On Attention And Perceptual Inference, Maria C. Potts

Graduate Theses, Dissertations, and Problem Reports (ETD)

Previous research has shown that animals vary in the degree to which they attribute incentive salience to reward predictive cues. In Pavlovian conditioning, two behavioral phenotypes emerge: goal-tracking (GT), in which animals approach the site of the reward, and sign-tracking (ST), in which animals approach the conditioned stimulus and interact with it as if it has become a reward in its own right. ST has been associated with higher rates of impulsivity, drug reinstatement, and relapse, and is thought to confer addiction vulnerability. Though some studies have suggested that similar phenotypes exist in humans and are possibly related to addiction …


Association Of Circulating Ketone Bodies With Cognitive Performance And Dementia In The Multi-Ethnic Study Of Atherosclerosis (Mesa), Parag Anilkumar Chevli, Christopher L Schaich, Alexis C Wood, Luqman A Tk, Anurag Mehta, Vardhmaan Jain, Margery Connelly, Suzanne Craft, Elad Shemesh, José A Luchsinger, Kathleen M Hayden, Bonnie Colleen Sachs, Timothy M Hughes, Michael D Shapiro 2024 The Texas Medical Center Library

Association Of Circulating Ketone Bodies With Cognitive Performance And Dementia In The Multi-Ethnic Study Of Atherosclerosis (Mesa), Parag Anilkumar Chevli, Christopher L Schaich, Alexis C Wood, Luqman A Tk, Anurag Mehta, Vardhmaan Jain, Margery Connelly, Suzanne Craft, Elad Shemesh, José A Luchsinger, Kathleen M Hayden, Bonnie Colleen Sachs, Timothy M Hughes, Michael D Shapiro

Faculty, Staff and Students Publications

Introduction

Growing interest centers on the association between circulating ketone bodies (KB) and cognitive function, notably in aging and neurodegenerative diseases.

Methods

Associations of plasma KB with incident dementia and cognitive performances were examined among Multi‐Ethnic Study of Atherosclerosis (MESA) participants. KB were measured using plasma samples collected following an overnight fasting at Exam 1 (2000–02) and detailed cognitive testing at Exam 5 (2010–2012, N = 4392), Exam 6 (2016–2018, N = 1838), and in MESA‐MIND (2019–2021, N = 2060).

Results

Over 16.7 years, a doubling of total KB was associated with a greater risk of incident dementia (hazard ratio …


Review Of Steve Taylor’S Disconnected, Zeke Floro 2023 California Institute of Integral Studies

Review Of Steve Taylor’S Disconnected, Zeke Floro

Journal of Conscious Evolution

This article presents a review of Steve Taylor’s (2023) book, DisConnected: The Roots of Human Cruelty and How Connection Can Heal the World. Taylor makes a significant contribution to the study of psychological development, spiritual growth, and the overall evolution of consciousness by thoughtfully examining the disconnection that underlies violent crime, terrorism, dishonest business practices, authoritarianism, religious extremism, surrender of autonomy, culture wars, and polarized politics. He convincingly argues that disconnection is not the default state of humanity, but rather an aberration, and that dark aspects of human nature emerge from an environmentally conditioned sense of separation and inability to …


Assessment Of Deficits In Specific Cognitive Domains In Older Adults Living With Hiv., Andrea Reyes-Vega, Harideep Samanapally, Rishikesh Rijal, Stephen P. Furmanek, Christopher B. Shields, Brandon C. Dennis, Smita Ghare, Shirish Barve 2023 University of Louisville

Assessment Of Deficits In Specific Cognitive Domains In Older Adults Living With Hiv., Andrea Reyes-Vega, Harideep Samanapally, Rishikesh Rijal, Stephen P. Furmanek, Christopher B. Shields, Brandon C. Dennis, Smita Ghare, Shirish Barve

Faculty and Staff Scholarship

A significant proportion of people living with HIV (PLWH) have cognitive impairment. Moreover, approximately 70% of PLWH in the United States will be ≥50 years old by 2030, raising concerns of a higher incidence of dementia as they age. Accordingly, there is a clinical need to monitor their cognitive status. The aim of this study was to delineate specific cognition areas impacted in OALWH with a clinical diagnosis of neurocognitive impairment. We used a comprehensive set of tests (paper and NIH Toolbox Cognition Battery), to assess different cognitive domains in a total of 25 OALWH ≥ 50 years. 64% were …


Direct Relationships Between The Five Internal Senses: The Extremes And In-Between Of The Inner Experience, Sydnie Hoyt, Camryn O'Neal, Miranda Brannum, Sara Bagley 2023 Lindenwood University

Direct Relationships Between The Five Internal Senses: The Extremes And In-Between Of The Inner Experience, Sydnie Hoyt, Camryn O'Neal, Miranda Brannum, Sara Bagley

The Confluence

Inner experience of all 5 modalities were investigated to determine if there were correlations amongst them and how visual mental imagery and internal hearing were used in an applied story. Our sample (N = 137) completed the Vividness of Visual Imagery Questionnaire (VVIQ; Marks, 1973) and the Plymouth Sensory Imagery Questionnaire (Psi-Q; Andrade et al., 2013) to obtain trait measures of the different modalities within the inner experience. Results showed statistically significant positive correlations between each of the trait measures of the 5 sensory modalities (visual mental imagery, inner hearing, taste, smell, and touch). Based on their VVIQ total scores, …


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