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Frontal Brain Injury: Effects On Flexibility, Impulse Control, And Attention, Christopher Matthew O'Hearn 2020 WVU

Frontal Brain Injury: Effects On Flexibility, Impulse Control, And Attention, Christopher Matthew O'Hearn

Graduate Theses, Dissertations, and Problem Reports (ETD)

Traumatic Brain Injury (TBI) is defined as an impact to the head, penetration of the skull, or rapid deceleration of the skull, resulting in an alteration of brain function or neurological deficit. Cognitive deficits are common following TBI and often go unresolved due to a lack of effective treatments. These deficits often perseverate into the chronic post injury phase, so the development of rehabilitative strategies is imperative. Behavioral flexibility, impulse control, and attention are a few cognitive processes that are commonly affected by TBI. The current research compares these processes between rats with and without a severe frontal brain injury …


Minocycline As A Treatment For Traumatic Brain Injury-Induced Impulsive And Attentional Deficits, Kristen M. Pechacek 2020 West Virginia University

Minocycline As A Treatment For Traumatic Brain Injury-Induced Impulsive And Attentional Deficits, Kristen M. Pechacek

Graduate Theses, Dissertations, and Problem Reports (ETD)

Traumatic brain injury (TBI) impacts millions worldwide and can cause lasting psychiatric symptoms. Chronic neuroinflammation is a characteristic of post-injury pathology and is positively associated with psychiatric conditions such as ADHD and bipolar disorder. Therefore, the current study sought to treat TBI-induced impulsivity and inattention using minocycline, an antibiotic with anti-inflammatory properties. Rats were trained on the five-choice serial reaction time task (5CSRT), a measure of motor impulsivity and attention. After behavior was stable on the 5CSRT, rats received either a bilateral frontal TBI or sham procedure. Minocycline was given at either 1 h post-injury or beginning at 8 weeks …


Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref 2020 CUNY City College

Mechanisms Of Value-Biased Prioritization In Fast Sensorimotor Decision Making, Kivilcim Afacan-Seref

Dissertations and Theses

In dynamic environments, split-second sensorimotor decisions must be prioritized according to potential payoffs to maximize overall rewards. The impact of relative value on deliberative perceptual judgments has been examined extensively, but relatively little is known about value-biasing mechanisms in the common situation where physical evidence is strong but the time to act is severely limited. This research examines the behavioral and electrophysiological indices of how value biases split-second perceptual decisions and the possible mechanisms underlying the process. In prominent decision models, a noisy but statistically stationary representation of sensory evidence is integrated over time to an action-triggering bound, and value-biases …


Construct Validity Of The Teate Depression Inventory: Convergent And Discriminant Validity And Equivalence For Black/African American And White/Caucasian Samples, Dylin Coons 2020 Eastern Illinois University

Construct Validity Of The Teate Depression Inventory: Convergent And Discriminant Validity And Equivalence For Black/African American And White/Caucasian Samples, Dylin Coons

Masters Theses

The purpose of this study was to replicate the construct validity of a new measure of depression, the Teate Depression Inventory (TDI; Balsamo & Saggino, 2013), with the primary focus on Black/African American participants. Research has purported that Black/African Americans experience inequality in obtaining mental health care for internalizing disorders. This may partially be caused by errors in diagnosing these individuals with symptoms. Correctly diagnosing internalizing disorders is a critical step in obtaining appropriate treatment. More research on depression and anxiety is needed to enhance mental health practices by addressing the need for professionals to be culturally competent and conscious …


Ketamine Pre-Exposure Does Not Influence Later-Life Responses To Reward-Related Stimuli In Female C57bl/6 Mice, Israel Garcia 2020 University of Texas at El Paso

Ketamine Pre-Exposure Does Not Influence Later-Life Responses To Reward-Related Stimuli In Female C57bl/6 Mice, Israel Garcia

Open Access Theses & Dissertations

Preclinical work indicates that exposure to traditional antidepressant medications, in adolescent and adult female subjects, alters reward-related behavior later in life. In recent years, the anesthetic ketamine (KET), now used as a fast-acting antidepressant, has shown promising therapeutic efficacy for the management of depression. However, the potential long-term behavioral consequences of KET exposure across development have not been thoroughly assessed. Thus, to address this issue, we examined if KET exposure, during adolescence or early adulthood, results in enduring alterations in responsivity to the rewarding properties of sucrose and cocaine later in life. Specifically, female C57BL/6 mice were randomly assigned to …


Attentional Control In Infancy: The Role Of Sociodemographic Risk, Cortisol, And The Home Environment, Hannah B. White 2020 University of Kentucky

Attentional Control In Infancy: The Role Of Sociodemographic Risk, Cortisol, And The Home Environment, Hannah B. White

Theses and Dissertations--Psychology

Infants’ ability to channel their cognitive resources by controlling their visual attention allows them to be active agents in their learning and development. Individual differences in attentional control have been linked to a wide variety of developmental outcomes including disparities between social classes in cognitive functioning. However, it is yet unknown when in development differences in attentional control related to sociodemographic factors emerge, or how factors of the home environment and the infant’s stress response relate to this effect. Accordingly, Experiment 1 examined whether certain sociodemographic factors, such as socioeconomic and minority status, predict 3.5-month-old infants’ (N = 102) …


Ethanol Sustains Phosphorylated Tau Protein Immunofluorescence In The Cultured Neonatal Rat Hippocampus: Implications For Fetal Alcohol Spectrum Disorders, Caleb Seth Bailey 2020 University of Kentucky

Ethanol Sustains Phosphorylated Tau Protein Immunofluorescence In The Cultured Neonatal Rat Hippocampus: Implications For Fetal Alcohol Spectrum Disorders, Caleb Seth Bailey

Theses and Dissertations--Psychology

Fetal Alcohol Spectrum Disorders (FASDs) are comprised of developmental, behavioral, and cognitive abnormalities caused by prenatal alcohol exposure, affecting an estimated 2%-5% of childrenand costing up to $4 billion annually in the United States alone. Although some behavioral therapies can help, the biochemical mechanisms that underpin FASDs need further elucidation for development of more efficacious therapeutics. The tau protein modulates cytoskeletal structure in neurons, and thereby plays an integral role in proper development and function of the central nervous system, but its function is altered by its phosphorylation state, such that increased phosphorylation reduces tau protein function. The tau protein …


Does Testosterone Affect Sexist Attitudes In Men? A Simulated Analysis, Steven R. Bowman 2020 Cal Poly Humboldt

Does Testosterone Affect Sexist Attitudes In Men? A Simulated Analysis, Steven R. Bowman

Cal Poly Humboldt theses and projects

Sexism continues to negatively affect the lives of women across many cultures and modern societies. Although sexism has a damaging effect on people overall, women are disproportionately affected. Previous research on the topic generally explores attitudes, culture, socioeconomic status, sexual and violent crime census data, and developmental factors, but there is a lack of research investigating potential links among biological factors, such as hormone levels, and sexist attitudes. The present study used simulated data to simulate a study investigating the relationship between endogenous testosterone, cognitive aggression, and sexist attitudes. Using the faux, pwr2ppl, and ProcessR packages in R Studio open-source …


Cuteness As A Prime To Enhance Emotional Recognition, Andrew Diaz 2020 Humboldt State University

Cuteness As A Prime To Enhance Emotional Recognition, Andrew Diaz

Cal Poly Humboldt theses and projects

The ability to recognize emotional expressions has important implications for survival and cooperation. Failing to recognize emotions indicative of some form of threat (anger, fear, disgust) may be particularly costly given these emotional expressions communicate a potential source of danger in the environment. Previous studies have shown that people tend to recognize threatening emotions faster and more accurately than non-threatening emotions. Infantile characteristics (kindchenschema) readily capture the attention of adults and have been shown to influence a variety of behaviors associated with caretaking; viewing cute stimuli increases behavioral carefulness on various visual and motor tasks. The current study …


How Does Eye Movement Desensitization And Reprocessing (Emdr) Work? An Examination Of The Potential Mechanisms Of Action, Sara Forster 2020 Pepperdine University

How Does Eye Movement Desensitization And Reprocessing (Emdr) Work? An Examination Of The Potential Mechanisms Of Action, Sara Forster

Theses and Dissertations

A mounting body of evidence suggests that Eye Movement Desensitization and Reprocessing therapy (EMDR) is successful in reducing the impact of posttraumatic symptoms. Although the exact mechanisms of action remain unknown, theories from the psychological to the neuroscientific continue to emerge, expand, and evolve. This study will examine four of the most prominent theories to date and weigh the evidence for and against each one. It will also review, compare, and contrast the theories, evaluate the research supporting each one, and propose the most likely explanation for EMDR's success given the state of the research. Neurobiological mechanisms and correlates as …


Working Memory Deficits Are Associated With Altered Regional Brain Volume And Structural Connectivity In Children With Chromosome 22q11.2 Deletion Syndrome., Diana Hobbs 2019 University of New Orleans

Working Memory Deficits Are Associated With Altered Regional Brain Volume And Structural Connectivity In Children With Chromosome 22q11.2 Deletion Syndrome., Diana Hobbs

LSU New Orleans Theses and Dissertations

Background: Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) exhibit nonverbal learning disability that may manifest in part because of working memory (WM) deficits. 22q11.2DS is a complex developmental disorder with serious physical, learning, cognitive, and psychiatric symptoms including a risk of developing schizophrenia 30 times that of the general population. WM impairment likely contributes to and exacerbates learning difficulties, school problems, existing neuropsychological disorders such as attention deficit hyperactivity disorder (ADHD); and a poor WM may be a biological risk marker for future mental illness. WM impairment is established in this population, but less is known about its neurological origins. …


Structural Connectivity And Immunological Correlates Of Emotion Processing In Children With Chromosome 22q11.2 Deletion Syndrome, Ashley F. P. Sanders 2019 University of New Orleans

Structural Connectivity And Immunological Correlates Of Emotion Processing In Children With Chromosome 22q11.2 Deletion Syndrome, Ashley F. P. Sanders

LSU New Orleans Theses and Dissertations

Neurological abnormalities are associated with emotion processing deficits seen in children with neurodevelopmental disorders. Research suggests that inflammatory mechanisms can negatively impact brain structure and function and are thought to play a role in these processing atypicalities. Children with chromosome 22q11.2 deletion syndrome (22q11.2DS) exhibit emotion processing impairments and associated neural abnormalities. We investigated the roles of inflammatory factors and structural connectivity in relation to emotion processing deficits in 28 children with 22q11.2DS and 33 typically developing children (M = 11.12 years old; SD = 2.17). Results indicate poorer social skills and significantly lower emotion recognition scores in children …


Sexting Among Adolescents: Examining The Association Between Sexting And Self-Esteem, Hanaah Fannin 2019 Dominican University of California

Sexting Among Adolescents: Examining The Association Between Sexting And Self-Esteem, Hanaah Fannin

Physician Assistant Studies | Student Capstone Presentations

The primary objective of this study is to provide a systematic review of the published literature, examining the association between sexting and self-esteem in adolescents, and to identify gaps in existing knowledge to provide recommendations for future research.


Anxiety Symptoms As A Predictor Of Head And Neck Cancer Survival And Potential For Mediation By Cancer Treatment Response., Tyler D. Pollitt 2019 University of Louisville

Anxiety Symptoms As A Predictor Of Head And Neck Cancer Survival And Potential For Mediation By Cancer Treatment Response., Tyler D. Pollitt

College of Arts & Sciences Senior Theses

BACKGROUND:

Head and neck cancers (HNC) are associated with high rates of depression, which seems to affect overall survival. However, little attention has been paid to the effects of anxiety on overall survival, though anxiety has been shown to activate inflammatory pathways implicated in cancer symptom development and progression. Here it was hypothesized that higher pre-treatment anxiety levels in HNC patients would predict poorer overall two-year survival and a higher likelihood of subsequent HNC treatment failure. Additionally, we expected that the relationship between higher pre-treatment anxiety and poorer two-year overall survival would be mediated by treatment failure.

METHODS:

Patients (n …


The Influence Of Neural Reward Processing On Memory In Depression, Nathan M. Hager 2019 Old Dominion University

The Influence Of Neural Reward Processing On Memory In Depression, Nathan M. Hager

Psychology Theses & Dissertations

Theories and research suggest that depression involves impaired reward sensitivity and a deficit in memory for rewarding stimuli. Some researchers propose that this memory deficit may result from reduced neural reward sensitivity, which impairs the encoding of reward-related memories, but few studies have directly probed this connection. Such research may benefit from examining the reward positivity (RewP), an event-related potential (ERP) previously linked to reduced reward sensitivity in depression. Undergraduates with high or low self-reported depression completed a task in which they chose one of three doors, revealing a neutral word written in a color which indicated an outcome of …


Morphology, Molecular Characterization And Habitat Preference Of Harmful Benthic Dinoflagellate Gambierdiscus (Dinophyceae) In Malaysia, Nurin Izzati Mustapa 2019 Universiti Malaya

Morphology, Molecular Characterization And Habitat Preference Of Harmful Benthic Dinoflagellate Gambierdiscus (Dinophyceae) In Malaysia, Nurin Izzati Mustapa

Student Works (2020-2029)

Ciguatera fish poisoning (CFP) is a type of illness that causes human intoxication after consuming contaminated coral fishes. The neurotoxins, ciguatoxins, are produced by species of Gambierdiscus, one of the harmful benthic dinoflagellates. Identification of harmful dinoflagellate species is important to gain further insights into the global dispersion. In this study, morphological characteristics of species in the genus Gambierdiscus and their habitat preferences were investigated. Field sampling was undertaken at Pulau Rawa, Terengganu and Pulau Sibu, Johor. Single cells of Gambierdiscus were isolated and clonal cultures were established. Morphology of Gambierdiscus was examined by using light and scanning electron microscopes. …


Digital Addiction: A Conceptual Overview, Amarjit Kumar Singh, Pawan Kumar Singh 2019 Chapra Cental School (CCS), Chapra, Bihar

Digital Addiction: A Conceptual Overview, Amarjit Kumar Singh, Pawan Kumar Singh

Library Philosophy and Practice (e-journal)

Abstract

Digital addiction referred to an impulse control disorder that involves the obsessive use of digital devices, digital technologies, and digital platforms, i.e. internet, video game, online platforms, mobile devices, digital gadgets, and social network platform. It is an emerging domain of Cyberpsychology (Singh, Amarjit Kumar and Pawan Kumar Singh; 2019), which explore a problematic usage of digital media, device, and platforms by being obsessive and excessive. This article analyses, reviewed the current research, and established a conceptual overview on the digital addiction. The research literature on digital addiction has proliferated. However, we tried to categories the digital addiction, according …


Superior Colliculus Lesions Lead To Disrupted Responses To Light In Diurnal Grass Rats (Arvicanthis Niloticus), Andrew J. Gall, Alyssa M. Goodwin, Ohanes S. Khacherian, Laura B. Teal 2019 Hope College

Superior Colliculus Lesions Lead To Disrupted Responses To Light In Diurnal Grass Rats (Arvicanthis Niloticus), Andrew J. Gall, Alyssa M. Goodwin, Ohanes S. Khacherian, Laura B. Teal

Faculty Publications

The circadian system regulates daily rhythms of physiology and behavior. Although extraordinary advances have been made to elucidate the brain mechanisms underlying the circadian system in nocturnal species, less is known in diurnal species. Recent studies have shown that retinorecipient brain areas such as the intergeniculate leaflet (IGL) and olivary pretectal nucleus (OPT) are critical for the display of normal patterns of daily activity in diurnal grass rats (Arvicanthis niloticus). Specifically, grass rats with IGL and OPT lesions respond to light in similar ways to intact nocturnal animals. Importantly, both the IGL and OPT project to one another …


The Biopsychology Of Ending Poverty: Lessons From Research On Economic Instability, Household Chaos, And Child Cortisol, Eleanor D. Brown 2019 West Chester University of Pennsylvania

The Biopsychology Of Ending Poverty: Lessons From Research On Economic Instability, Household Chaos, And Child Cortisol, Eleanor D. Brown

Sustainability Research & Practice Seminar Presentations

No abstract provided.


Bidirectional Associations Between Obesity And Cognitive Function In Midlife Adults: A Longitudinal Study, Andree HARTANTO, Jose C. YONG, Wei Xing TOH 2019 Singapore Management University

Bidirectional Associations Between Obesity And Cognitive Function In Midlife Adults: A Longitudinal Study, Andree Hartanto, Jose C. Yong, Wei Xing Toh

Research Collection School of Social Sciences

The links between obesity and cognition remain equivocal due to a variety of methodological limitations with current research, such as an overreliance on body mass index (BMI) as a measure of obesity, the use of cross-sectional designs, and inadequate specification over the domains of cognitive function to be examined. To address these issues, we used data from the Cognitive Project of the National Survey of Midlife Development in the United States, a large-scale, longitudinal dataset on non-institutionalized midlife adults (N = 2652), which enabled us to examine the long-term bidirectional relations between obesity and two latent factors of cognition—executive function …


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