Autotaxin: A Regulator Of Oligodendrocyte Differentiation,
2010
Virginia Commonwealth University
Autotaxin: A Regulator Of Oligodendrocyte Differentiation, Larra Yuelling
Theses and Dissertations
In order for oligodendrocyte progenitor cells (OPCs) to differentiate into fully mature, myelinating oligodendrocytes, they must be specified at the correct times and undergo coordinated changes in both gene expression and morphology. As oligodendrocytes differentiate, they transition from a bipolar morphology into a morphology characterized by a complex network of multiple processes, which will eventually generate membranous structures necessary for myelination of axonal segments. As changes are observed in cellular morphology, oligodendrocytes also undergo changes in their gene expression profile and express genes necessary for both early and later stages of development such as olig1 and myelin basic protein (mbp), …
Expanding The Treatment Window Raising The Bar For Patient Safety,
2010
Lehigh Valley Health Network
Expanding The Treatment Window Raising The Bar For Patient Safety, Claranne Mathiesen Rn, Msn, Cnrn
Patient Care Services / Nursing
No abstract provided.
