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Articles 661 - 690 of 1462
Full-Text Articles in Science and Technology Policy
Panorama Of Human Embryo-Derived Cells In Biomedicine And Progress In Their Research And Regulation, Jianchao Gao, Yaojin Peng, Wei Wei, Shuang Lu, Chenyan Gao
Panorama Of Human Embryo-Derived Cells In Biomedicine And Progress In Their Research And Regulation, Jianchao Gao, Yaojin Peng, Wei Wei, Shuang Lu, Chenyan Gao
Bulletin of Chinese Academy of Sciences (Chinese Version)
Since the establishment of the first human diploid cell line derived from aborted fetal tissue in the 1960s, human embryoderived cells have been widely used in biomedical field and significantly contributes to improving human health. In recent years, human pluripotent stem cells, including human embryonic stem cells (hESCs), have shown great therapeutic potential in regenerative medicine, and thus received great attention from governments and the public. However, due to various factors such as history, culture, religious beliefs, ethics and morality, research and application involving human embryo-derived cells have been controversial worldwide. This study explores the history and progress of human …
Electric Vehicles Contribute To China's Energy Security And Carbon Peaking And Carbon Neutrality, Jianfeng Guo, Xuemei Zhang, Qi Cao, Fu Gu
Electric Vehicles Contribute To China's Energy Security And Carbon Peaking And Carbon Neutrality, Jianfeng Guo, Xuemei Zhang, Qi Cao, Fu Gu
Bulletin of Chinese Academy of Sciences (Chinese Version)
The current international situation is complicated and unstable, and China is in the midst of an important economic transition as it deals with the twin concerns of energy security and carbon peaking and carbon neutrality (referred to as dual carbon goals). Although the dual carbon goals aim a strong emphasis on energy security, certain emission reduction strategies will place restrictions on energy security that is directly connected, such as energy supply and grid load, making it challenging to simultaneously fulfill the optimization goal. China now has the task of figuring out how to rationalize and optimize the coordinated promotion of …
Key Elements, Mechanism Analysis And Evaluation Indicators Of Digital And Intelligent Integration Transformation And Development Of Manufacturing Industry, Xiaoqiang Sun, Xiuyun Gao, Yumei Wang
Key Elements, Mechanism Analysis And Evaluation Indicators Of Digital And Intelligent Integration Transformation And Development Of Manufacturing Industry, Xiaoqiang Sun, Xiuyun Gao, Yumei Wang
Bulletin of Chinese Academy of Sciences (Chinese Version)
The digital and intelligent integration transformation of manufacturing industry has become an important driving force for the high-quality development of traditional manufacturing enterprises. This study clarifies the main research context and key issues of scholars on the digital and intelligent integration transformation of manufacturing industry, refines the goals, main elements, and influencing factors of digital and intelligent integration transformation of manufacturing industry, builds a power network model for the transformation and development of digital and intelligent integration of manufacturing industry according to the system feedback principle of system dynamics, analyzes the mechanism of action between various elements of the system, …
Policy Overview (January, 2024)
Policy Overview (January, 2024)
Bulletin of Chinese Academy of Sciences (Chinese Version)
No abstract provided.
Exploration And Reflection On Interaction Mechanism Between Transformation Of Scientific Communication Models And Technological Innovation, Jichang Dong, Weiwei Zhu, Chao Zhang, Zhou He
Exploration And Reflection On Interaction Mechanism Between Transformation Of Scientific Communication Models And Technological Innovation, Jichang Dong, Weiwei Zhu, Chao Zhang, Zhou He
Bulletin of Chinese Academy of Sciences (Chinese Version)
In today’s rapidly advancing technological landscape, science communication is closely intertwined with technological innovation, serving as a crucial element in influencing a country’s technological competitiveness and competing for the global scientific and technological discourse. This study delves into the historical context of science communication and the theoretical research and paradigm shifts surrounding it. It explores the symbiotic relationship between science communication and technological innovation, uncovering the mechanisms of their interactions. On this basis, the study examines exemplary practices in promoting science communication in major developed countries. In light of China’s current state of science communication, tentative strategies are proposed to …
Exploring The Potential Of E-Government In Reducing Corruption – Case Of Egypt, Mahinour Abou Elseoud
Exploring The Potential Of E-Government In Reducing Corruption – Case Of Egypt, Mahinour Abou Elseoud
Theses and Dissertations
Many countries have recognized the significance of electronic work transition to application, frequently known as e-government, with the purpose of improving their bureaucratic performance and reducing corruption. From an economic standpoint, transparency may boost government efficiency as it increases the government capacity and, eventually, fosters good governance by reducing corruption and inefficiency. As a result, this study aims to analyze the correlation between e-government and corruption, as well as whether e-government reduced the detrimental effects of corruption on public trust. To accomplish this objective, the thesis focuses on in-depth interviews with citizens of all ages, socioeconomic and educational backgrounds, as …
Clean Investment Monitor: Q4 2022 — Q3 2023, Madison Dwyer, Zachary Billot, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.
Clean Investment Monitor: Q4 2022 — Q3 2023, Madison Dwyer, Zachary Billot, Annie Vong, Caitlin J. Saladino, William E. Brown Jr.
Environment
This fact sheet presents investment trends in clean manufacturing, energy and industry, and retail in the Mountain West states of Arizona, Colorado, Nevada, New Mexico, and Utah. This fact sheet examines data from the Q3 2023 update of the Clean Investment Monitor (CIM), a joint project of Rhodium Group and the MIT Center for Energy and Environmental Policy Research.
Containerization Of Seafarers In The International Shipping Industry: Contemporary Seamanship, Maritime Social Infrastructures, And Mobility Politics Of Global Logistics, Liang Wu
Dissertations, Theses, and Capstone Projects
This dissertation discusses the mobility politics of container shipping and argues that technological development, political-economic order, and social infrastructure co-produce one another. Containerization, the use of standardized containers to carry cargo across modes of transportation that is said to have revolutionized and globalized international trade since the late 1950s, has served to expand and extend the power of international coalitions of states and corporations to control the movements of commodities (shipments) and labor (seafarers). The advent and development of containerization was driven by a sociotechnical imaginary and international social contract of seamless shipping and cargo flows. In practice, this liberal, …
Regulating Online Hate Speech: The Singapore Experiment, Siyuan Chen
Regulating Online Hate Speech: The Singapore Experiment, Siyuan Chen
Research Collection Yong Pung How School Of Law
In Singapore, the introduction of the Protection from Online Falsehoods and Manipulation Act 2019 (POFMA) generated considerable debate and feedback. One of the main concerns was whether the law would unduly restrict the freedom of expression. In focusing on the provisions of POFMA that could possibly apply to hate speech, this paper situates the criticisms within the larger framework of international human rights law and international practices and proposes some ways forward to improve the regulatory framework for online hate speech.
The Impact Of Accessible Data On Cyberstalking, Elise Kwan
The Impact Of Accessible Data On Cyberstalking, Elise Kwan
The Journal of Purdue Undergraduate Research
No abstract provided.
Editorial For Special Column “Biomanufacturing: Retrospect And Prospects”
Editorial For Special Column “Biomanufacturing: Retrospect And Prospects”
Bulletin of Chinese Academy of Sciences (Chinese Version)
No abstract provided.
Current Status And Applications Of Microbial Chassis Strains For Chinese Biomanufacturing Industry, Guoqiang Chen, Fuqing Wu, Shuang Zheng, Jun Ding, Junting Sheng
Current Status And Applications Of Microbial Chassis Strains For Chinese Biomanufacturing Industry, Guoqiang Chen, Fuqing Wu, Shuang Zheng, Jun Ding, Junting Sheng
Bulletin of Chinese Academy of Sciences (Chinese Version)
Biomanufacturing is an important component of new quality productive forces, representing the commanding height of the new round of technological revolution and serving as a new engine for industrial transformation following information technology. It demonstrates vast application prospects in fields such as renewable energy, advanced materials, biomedicine, green food, and environmental protection. Biomanufacturing utilizes chassis microorganisms similar as “microchip” to produce various bioproducts via processes including chassis design and construction, large-scale cell cultivation, and product purifications. Most chassis microorganisms in biomanufacturing were not domestically identified. This study summarizes the types of common chassis microorganisms both domestically and internationally, as well …
Recent Progress And Perspectives On Development Of Gene Editing Tools, Zixian Liu, Chengping Li, Gogo Jun-Jie Liu
Recent Progress And Perspectives On Development Of Gene Editing Tools, Zixian Liu, Chengping Li, Gogo Jun-Jie Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
The gene editing field has witnessed remarkable advancements in recent years, leading to the establishment and refinement of multidimensional gene editing platforms. These innovations have enabled precise targeted gene knockout, repair, and insertion. These tools have stimulated significant progress in fundamental research, therapeutics, agriculture, environment protection, and industrial applications. In this review, we provide a comprehensive overview of the milestones in gene editing tool development and offer perspectives on potential future directions for this rapidly evolving field.
Microbial Production Of Feed Amino Acids Promotes Reduction And Replacement Of Soybean Meal, Jia Liu, Qi Sheng, Kaifang Liu, Liming Liu
Microbial Production Of Feed Amino Acids Promotes Reduction And Replacement Of Soybean Meal, Jia Liu, Qi Sheng, Kaifang Liu, Liming Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
With the promotion of soybean meal reduction and substitution as well as lower-protein diet technologies, China has become a leading global producer of feed amino acids. However, the amino acid industry faces significant challenges due to its relatively late start in independently developing industrial strains, resulting in relatively lagging key economic and technical parameters and a less robust intellectual property framework. The rapid progress of synthetic biology has provided promising avenues for the design and optimization of industrial amino acid-producing strains, offering new opportunities for the amino acid fermentation industry to enhance the global competitiveness. This study offers an in-depth …
Current Status And Prospect Of Industrial Filamentous Fungi In Biomanufacturing, Zhiqiang Du, Ping Men, Yu Zhou, Xuan Zhang, Xuenian Huang, Xuefeng Lyu
Current Status And Prospect Of Industrial Filamentous Fungi In Biomanufacturing, Zhiqiang Du, Ping Men, Yu Zhou, Xuan Zhang, Xuenian Huang, Xuefeng Lyu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Filamentous fungi, a critical class of industrial microorganisms pivotal to the biomanufacturing industry, has extensive applications in various fields such as pharmaceuticals, food, agriculture, and chemical materials, which are playing a vital role in human life. Recently, innovations in synthetic biology have further driven the application of industrial filamentous fungi in biomanufacturing, highlighting their critical role in this field. This article presents a comprehensive review of the recent progress in the field, covering the latest developments in genetic modification techniques for industrial filamentous fungi, successful cases of rational strain improvement strategies aimed to enhance the quality and efficiency of current …
Efficient Discovery And Industrialized Manufacture Of Terpenoids, Haoming Chi, Liying Er, Tiangang Liu
Efficient Discovery And Industrialized Manufacture Of Terpenoids, Haoming Chi, Liying Er, Tiangang Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Terpenoids, a class of chemical entities with diverse biological activities in nature, demonstrate significant potential for applications in fields such as drug discovery, flavor industry, and agriculture. However, traditional methods face challenges, including inefficiency and high costs, in the discovery and industrialization of terpenoids. The rapid development of synthetic biology, genomics, artificial intelligence, and automation provides new opportunities for efficient terpenoid discovery and industrialization. This study comprehensively analyzes how these technologies synergistically contribute to the discovery, optimization, and large-scale production of terpenoids, and summarizes the current high-yield situations of terpenoids. The aim is to propose innovative strategies to accelerate technological …
Digitalized Design Of Cell Factory Enables Green Biomanufacturing, Fanze Meng, Rui Cao, Bing Hu, Lei Qin, Chun Li
Digitalized Design Of Cell Factory Enables Green Biomanufacturing, Fanze Meng, Rui Cao, Bing Hu, Lei Qin, Chun Li
Bulletin of Chinese Academy of Sciences (Chinese Version)
Green manufacturing is a modern manufacturing mode in the consideration of both environmental impact and efficiency of resource utilization, it represents a significant component of the “new productive force”. Centered on cell factories, green biomanufacturing leverages renewable resources to efficiently produce products that conform to the concepts of low-carbon, green, and sustainable development. The design of high-performance cell factories is pivotal for achieving efficient green biomanufacturing. Nevertheless, traditional cell factory design processes are complex, time-consuming, and labor-intensive. With advancements in artificial intelligence, digital-assisted cell factory design has emerged as a solution to save time and reduce costs. By integrating technologies …
Microsphere Core Technology Boosts Innovation Of Biopharmaceutical Industry Chain, Jie Wu, Weiqing Zhou, Lan Zhao, Guanghui Ma
Microsphere Core Technology Boosts Innovation Of Biopharmaceutical Industry Chain, Jie Wu, Weiqing Zhou, Lan Zhao, Guanghui Ma
Bulletin of Chinese Academy of Sciences (Chinese Version)
Advancements in life science and biotechnology have boosted the evolution of the biopharmaceutical industry with the continual emergence of biomedical products for disease prevention, diagnosis, and treatment. Microspheres, as crucial functional materials, play a significant role in the discovery, preparation, separation, and delivery of biological drugs due to their flexible size, morphology, structure, and function. This study reviews recent significant advancements in microspheres and their applications in cell culture, chromatographic separation, drug delivery, and as vaccine adjuvants. Additionally, it proposes future trends for the development of microspheres.
Research Progress In High-Throughput Phenotype Testing Technology And Equipment For Engineering Cells Based On Microfluidics, Shuang Li, Xiaojie Guo, Haibo Chen, Sisi Chen, Xin Da, Zhenghui Li, Qinxiu Liu, Yi Wang, Xinhui Xing, Chong Zhang
Research Progress In High-Throughput Phenotype Testing Technology And Equipment For Engineering Cells Based On Microfluidics, Shuang Li, Xiaojie Guo, Haibo Chen, Sisi Chen, Xin Da, Zhenghui Li, Qinxiu Liu, Yi Wang, Xinhui Xing, Chong Zhang
Bulletin of Chinese Academy of Sciences (Chinese Version)
Engineering cells are a core component of green bio-manufacturing. The efficient testing and acquisition of engineering cells with the desired phenotype is a critical factor in the successful implementation of bio-manufacturing. In recent years, based on microfluidics technologies, non-culture type single-cell phenotype high-throughput test equipment and culture type phenotype high-throughput test equipment for the growth and metabolism of single cell in a bioreactor have been developed such as microdroplet and microchamber, realizing high-throughput, automated, miniaturized, and integrated testing of the phenotypes of engineering cells and providing a powerful tool for the breeding of engineering cells. This review systematically compiles the …
Bioprocess Engineering And Intelligent Biomanufacturing, Guan Wang, Yingping Zhuang
Bioprocess Engineering And Intelligent Biomanufacturing, Guan Wang, Yingping Zhuang
Bulletin of Chinese Academy of Sciences (Chinese Version)
In the era of rapid development of synthetic biology, biomanufacturing, as a bridge between life sciences and engineering technologies, is gradually demonstrating its extraordinary potential to reshape industrial landscapes. However, challenges such as production efficiency, cost control, and process monitoring still hinder the smooth transition from laboratory innovations to industrial-scale implementation. Intelligent biomanufacturing has emerged as a new form of productive force, offering innovative solutions to these problems. This study reviews the latest advances in bioprocess engineering and intelligent biomanufacturing, focusing on three key technological systems: intelligent sensing, intelligent analysis, and intelligent control. Intelligent sensing technology acts as the “eyes” …
Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu
Analysis And Reflections On Key Platform Facilities Construction Of Global Biomanufacturing Industry, Xiaoyan Wu, Fang Chen, Yaoying Shan, Anjing Lu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Biomanufacturing, an emerging production method, is becoming a significant trend in global economic development and has garnered widespread international attention. Platform facilities are vital to the biomanufacturing industry’s development, serving as both the foundation for technological innovation and the bridge between research outcomes and practical applications. This study analyzes three key types of platform facilities and their operational mechanisms: technology innovation platforms (exemplified by the U.S. Agile BioFoundry), pilot-scale platforms (represented by European Bio Base Europe Pilot Plant), and industry incubation platforms (illustrated by the UK SynbiCITE). Drawing from these successful examples and examining China’s current platform infrastructure, this paper …
Research On Innovative Development Path And Policy Guarantee Of China’S Synthetic Biology Industry, Hongjun Geng, Chang Wang
Research On Innovative Development Path And Policy Guarantee Of China’S Synthetic Biology Industry, Hongjun Geng, Chang Wang
Bulletin of Chinese Academy of Sciences (Chinese Version)
Synthetic biology is hailed as the third revolution in life sciences after the discovery of the DNA double helix structure and genomic technology, and is the core driving force for the leapfrog development of next-generation biomanufacturing and the future bioeconomy, opening up an opportunity window for the reshaping of the global manufacturing map. How to strategically position the synthesis biology industry and seize the strategic high ground in the industry is a core topic of interest for global science and technology powers and manufacturing powers. Based on the identification of problems in the development of China’s synthesis biology industry, this …
Artificial Intelligence Driven Information Technology System Restructuring And Reconstruction—Review Of Information Science & Technology In China: A Roadmap To 2050, Xuehai Hong
Bulletin of Chinese Academy of Sciences (Chinese Version)
The Information Science & Technology in China: A Roadmap to 2050 and Information Technology: Accelerating the Integration of Human Machine Things have predicted the long-term development of China’s information technology field. This study reviews the development and changes in the field of information technology in the past 15 years, and compares them with the initial predictions, pointing out that some important judgments made at the beginning were in line with expectations. In recent years, the global development of information technology has entered a slow period, while the rapid evolution of the new generation of artificial intelligence will bring new opportunities …
Scientific Approach To Building A Highland Of Ecological Civilization In Xizang Of China, Xiaodan Wang, Jianxin Zhang, Da Wei, Hui Zhao, Jiangtao Hong, Yuling Liang, Yahui Qi, Zhengrong Yuan
Scientific Approach To Building A Highland Of Ecological Civilization In Xizang Of China, Xiaodan Wang, Jianxin Zhang, Da Wei, Hui Zhao, Jiangtao Hong, Yuling Liang, Yahui Qi, Zhengrong Yuan
Bulletin of Chinese Academy of Sciences (Chinese Version)
Xizang, which plays an important barrier role in maintaining national ecological security, is a unique region that ensures China’s sustainable development and leads the construction of national ecological civilization. The Seventh Central Conference on the Work of Xizang has set clear goals and specific requirements for building an ecological civilization highland on the Qinghai-Xizang Plateau, which were identified as a new mission and task of Xizang government for environmental protection and sustainable development in the new era. Based on the previous research achievements about national ecological security barrier, this work further carried out the systematic study of ecological civilization highland …
Internal Logic And Policy Recommendations Of Big Data To Support High-Quality Development Of Modern Agricultural Industry, Yingming Li, Zitong Wang, Mingyue Wang, Shiyi Liu
Internal Logic And Policy Recommendations Of Big Data To Support High-Quality Development Of Modern Agricultural Industry, Yingming Li, Zitong Wang, Mingyue Wang, Shiyi Liu
Bulletin of Chinese Academy of Sciences (Chinese Version)
Clarifying the internal logic of big data to support modern agricultural production is helpful to cultivate and develop new quality productive forces in agriculture. From the perspective of economics, this study proposes that the role of big data in modern agricultural production is mainly reflected in two levels. Firstly, it improves the total factor productivity of the traditional agricultural production function. Secondly, it changes the factor endowment structure of agricultural production and forms a new agricultural production function. Based on these, the realization form of big data to support modern agricultural production can be summarized as improving the efficiency of …
Strengthen Research On Environmental Control Technologies And Management Policies For Emerging Contaminants In China, Ying Ma, Xiang Li, Yongming Luo
Strengthen Research On Environmental Control Technologies And Management Policies For Emerging Contaminants In China, Ying Ma, Xiang Li, Yongming Luo
Bulletin of Chinese Academy of Sciences (Chinese Version)
The prevention and management of emerging contaminants (ECs) have become critical measures in China’s battle against environmental pollution. This study focuses on the environmental control technologies and policy governance related to emerging contaminants (ECs), analyzing their environmental pathways and challenges to public health, and highlighting advancements and limitations in current physical, chemical, and biological control technologies. Based on a comprehensive analysis of international policies and regulations on ECs control, the study identifies existing challenges and shortcomings in domestic management. Recommendations are proposed to enhance research on environmental control technologies and policies for ECs in China, aiming to provide insights for …
Development And Utilization Of Mineral Resources In The Arctic And China’S Strategic Countermeasures, Yina Su
Development And Utilization Of Mineral Resources In The Arctic And China’S Strategic Countermeasures, Yina Su
Bulletin of Chinese Academy of Sciences (Chinese Version)
There are abundant strategic mineral resources as oil, gas, iron ore, copper, and nickel in the Arctic region. If the Arctic routes can be opened in the future, they will become another important transportation channels connecting the Pacific and Atlantic Oceans, following the Panama Canal and the Suez Canal, which may reshape the world’s maritime trade and transportation pattern. With the development of science and technology, increase in mineral resources consumption and changes in the international environment, the strategic position of the Arctic region is increasingly elevated, and the United States, Russia and some other countries of the European Union …
Redesign And De Novo Design Of Circular Blue Bioindustry, Wei Zhang, Shufeng Zhang, Hantao Zhou, Minhan Dai
Redesign And De Novo Design Of Circular Blue Bioindustry, Wei Zhang, Shufeng Zhang, Hantao Zhou, Minhan Dai
Bulletin of Chinese Academy of Sciences (Chinese Version)
The future marine bioindustry, which features advanced green intelligent biomanufacturing and high-value marine bioproducts, is a strategically emerging marine industry. This study proposes a new industrial development model for the circular blue bioindustry, founded on simultaneously optimizing the sustainable utilization of marine bioresources and protecting the ecological environment. Through in-depth analysis of the current situation, challenges, and potential development opportunities of the global and Chinese marine bioindustries underpinning sustainable development, theoretical framework, approaches and implementation pathways have been established to redesign the existing marine bioindustry and de novo design of the emerging marine bioindustry. Future key development priorities are suggested …
Analysis On Development Status And Characteristics Of Non-Governmental Bio-Safety And Bio-Security Think Tanks In The United States, Wenbing Ma, Qiang Song, Lei Wang
Analysis On Development Status And Characteristics Of Non-Governmental Bio-Safety And Bio-Security Think Tanks In The United States, Wenbing Ma, Qiang Song, Lei Wang
Bulletin of Chinese Academy of Sciences (Chinese Version)
At present, the complexity of bio-safety governance is becoming increasingly prominent, and complex issues such as security and development in the bio-economy, preparedness and response to infectious disease pandemics, the interweaving and integration of bio-security and other security factors, and the integration of scientific and technological factors and security factors urgently require think tanks to conduct systematic, comprehensive and forward-looking assessments and provide professional solutions. Rooted in the relatively mature experience in the construction of think tanks in the United States, a number of bio-safety and bio-security think tanks with greater influence have been developed, which have acted as an …
Policy Overview (December, 2024)
Policy Overview (December, 2024)
Bulletin of Chinese Academy of Sciences (Chinese Version)
No abstract provided.