Open Access. Powered by Scholars. Published by Universities.®

Biology Commons™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 3961 - 3990 of 39065

Full-Text Articles in Biology

Environmental Implications Of Modern Food Production: An Analysis For The Conscious Consumer, Jessica T. Coming Jan 2024

Environmental Implications Of Modern Food Production: An Analysis For The Conscious Consumer, Jessica T. Coming

Cal Poly Humboldt theses and projects

This project explores the pathways by which agriculture affects the environment and determines which foods have the greatest climate, water, and land impacts. Agricultural effects on the environment are extensive, from loss of habitat and declines in regional biodiversity to disruption of global nutrient cycles and climate change. Global food production accounts for 26-34% of annual anthropogenic greenhouse gas emissions, makes up 38-46% of habitable land, and is responsible for 70% of freshwater extraction. The effect of agriculture on the environment is most significantly dictated by what type of food is being produced. Animal-based food products consistently have the highest …

Go to article

Estimating Steelhead Smolt Abundance From A Mixed Resident/Anadromous Oncorhynchus Mykiss Population, Gabriel Temple Jan 2024

Estimating Steelhead Smolt Abundance From A Mixed Resident/Anadromous Oncorhynchus Mykiss Population, Gabriel Temple

All Master's Theses

Effective management of fish populations in inland waters requires, at the most fundamental level, a basic understanding of population abundance. This is especially important for critically depressed species having high conservation value. Unfortunately, due to their critically depressed abundance, the anadromous form of Oncorhynchus mykiss, known as Steelhead Trout, has high conservation value in the upper Yakima Basin located in central Washington State. However, the resident form of O. mykiss, known as Rainbow Trout, are numerous in the watershed. We used a juvenile tagging study coupled with a long-term population monitoring study to disaggregate this mixed O. mykiss …

Go to article

Drosophila Parasitoids Go To Space: Unexpected Effects Of Spaceflight On Hosts And Their Parasitoids, Jennifer Chou, Johnny R. Ramroop, Amanda M. Saravia-Butler, Brian Wey, Matthew P. Lera, Medaya L. Torres, Mary Ellen Heavner, Janani Iyer, Siddhita D. Mhatre, Sharmila Bhattacharya, Shubha Govind Jan 2024

Drosophila Parasitoids Go To Space: Unexpected Effects Of Spaceflight On Hosts And Their Parasitoids, Jennifer Chou, Johnny R. Ramroop, Amanda M. Saravia-Butler, Brian Wey, Matthew P. Lera, Medaya L. Torres, Mary Ellen Heavner, Janani Iyer, Siddhita D. Mhatre, Sharmila Bhattacharya, Shubha Govind

Publications and Research

While fruit flies (Drosophila melanogaster) and humans exhibit immune system dysfunction in space, studies examining their immune systems’ interactions with natural parasites in space are lacking. Drosophila parasitoid wasps modify blood cell function to suppress host immunity. In this study, naive and parasitized ground and space flies from a tumor-free control and a blood tumor-bearing mutant strain were examined. Inflammation-related genes were activated in space in both fly strains. Whereas control flies did not develop tumors, tumor burden increased in the space-returned tumor-bearing mutants. Surprisingly, control flies were more sensitive to spaceflight than mutant flies; many of their …

Go to article

South America Holds The Greatest Diversity Of Native Daisies (Asteraceae) In The World: An Updated Catalogue Supporting Continental-Scale Conservation, Andrés Moreira-Muñoz, Marcelo Monge, Mariana A. Grossi, Fabio Andrés Ávila, Vanezza Morales-Fierro, Gustavo Heiden, Berni Britto, Stephan Beck, Jimi N. Nakajima, Vanina G. Salgado, Juan Facundo Rodríguez-Cravero, Diego G. Gutiérrez Jan 2024

South America Holds The Greatest Diversity Of Native Daisies (Asteraceae) In The World: An Updated Catalogue Supporting Continental-Scale Conservation, Andrés Moreira-Muñoz, Marcelo Monge, Mariana A. Grossi, Fabio Andrés Ávila, Vanezza Morales-Fierro, Gustavo Heiden, Berni Britto, Stephan Beck, Jimi N. Nakajima, Vanina G. Salgado, Juan Facundo Rodríguez-Cravero, Diego G. Gutiérrez

Publications and Research

Asteraceae is the world’s richest plant family and is found on all continents, in environments ranging from the coast to the highest mountains. The family shows all growth forms and, as in other angiosperm families, species richness is concentrated in tropical regions. South America has the highest diversity of Asteraceae in the world, yet taxonomic and distributional knowledge gaps remain. This study compiles an updated catalog of Asteraceae native to South America, based on national and regional checklists and ongoing large-scale flora projects. The resulting checklist includes a total of 6,940 species and 564 genera native to South America to …

Go to article

Advanced Detection Of Sars-Cov-2 And Omicron Variants Via Mxene-Graphene Hybrid Biosensors Utilizing Nucleic Acid Probes, Jiaoli Li, Yuwei Zhang, Congjie Wei, Yanxiao Li, Zhekun Peng, Hsin Yin Chuang, Logan Pearce, Adrianus Boon, Yue-Wern Huang, Dong Hyun Kim, Risheng Wang, Chenglin Wu Jan 2024

Advanced Detection Of Sars-Cov-2 And Omicron Variants Via Mxene-Graphene Hybrid Biosensors Utilizing Nucleic Acid Probes, Jiaoli Li, Yuwei Zhang, Congjie Wei, Yanxiao Li, Zhekun Peng, Hsin Yin Chuang, Logan Pearce, Adrianus Boon, Yue-Wern Huang, Dong Hyun Kim, Risheng Wang, Chenglin Wu

Biological Sciences Faculty Research & Creative Works

Low-cost biosensors that can rapidly and widely detect viruses are critical for faster diagnosis and treatment decision-making, especially for infections. The commonly used field-effect transistor is sensitive to the biomarker's detection but struggles with precise detection, particularly of nontargets such as ions and proteins. To overcome this limitation, we developed a field-effect transistor biosensor design based on MXene-graphene materials to increase the accuracy and sensitivity of virus detection. Based on the hybridization process between two complementary DNA strands, single-stranded nucleic acids were immobilized on the sensing surface via 3-aminopropyltriethoxysilane and glutaraldehyde to capture the nucleic acids of the target virus. …

Go to article

Calcium Permeability Of Rat Trpv1 In A Close State When Expressed In Xenopus Laevis Oocytes, Zinnia Adhikary Jan 2024

Calcium Permeability Of Rat Trpv1 In A Close State When Expressed In Xenopus Laevis Oocytes, Zinnia Adhikary

Theses and Dissertations

Transient Receptor Potential V1 (TRPV1) is a nonselective cation channel, which is expressed in nociceptors/ pain detecting receptors. Activated by a wide variety of exogenous and endogenous physical and chemical stimuli such as heat, TRPV1 is involved in temperature detection, body temperature regulation, and pain perception. It is generally accepted that TRPV1's conductance to cations, including Ca2+, depends on its conformational change from a closed to an open state following gating. In the current study, I observed that the plasma membrane of Xenopus laevis oocytes, upon exogenous expression of rat TRPV1, exhibited weak permeability to Ca2+, as evidenced by the …

Go to article

Searching For Novel Mutations That Regulates The Mouse Polycystin-2 (Trpp2) Ion Channel, Akhilraj Rajan Pillai Jan 2024

Searching For Novel Mutations That Regulates The Mouse Polycystin-2 (Trpp2) Ion Channel, Akhilraj Rajan Pillai

Theses and Dissertations

Polycystin-2 (PC2) is an ion channel belonging to the polycystin subfamily of the transient receptor potential (TRP) cation channel superfamily. Mutations in PC2 are associated with autosomal dominant polycystic kidney disease (ADPKD), one of the most common genetic diseases in humans. Despite extensive studies over the past decades, the role of PC2 in normal and ADPKD kidneys remains largely unknown, and the activation and regulation of this ion channel are elusive. To gain a better understanding of the structure and function of the mouse PC2 channel, this study focused on generating five pore mutations in a gain-of-function (GOF) mutant of …

Go to article

Long Term Trends In Mortality Rates Of A Smallmouth Bass Population, Caleb D. Anderson Jan 2024

Long Term Trends In Mortality Rates Of A Smallmouth Bass Population, Caleb D. Anderson

Journal of Earth and Life Science

Smallmouth bass Micropterus dolomieu are known as a popular sport fish for anglers. When a known smallmouth bass fishery appears to have a dwindling population, it raises questions about the population health. A common indicator of the health of the population is the mortality rate. By comparing mortality, conclusions can be made on whether smallmouth bass are dying at a different rate in the system over time. Therefore, the objective of this study was to see if there had been a significant change in smallmouth bass mortality over a span of thirty years in Round Lake (DOW:010204), Aitkin County, Minnesota. …

Go to article

Relationship Between Northern Pike And Walleye Cpue In Minnesota Lakes, Simon Oslund Jan 2024

Relationship Between Northern Pike And Walleye Cpue In Minnesota Lakes, Simon Oslund

Journal of Earth and Life Science

Northern pike Esox lucius and walleye Sander vitreus are both top predators in freshwater systems. Due to their predatorial nature, high populations of one species can prohibit populations of the other species from thriving, specifically northern pike foraging on walleye. This information is tracked by the Minnesota Department of Natural Resources through catch per unit effort (CPUE). CPUE data was gathered for all lakes in Beltrami County, Minnesota, and a regression analysis was done to test for a relationship between pike and walleye. It was found that the relationship between northern pike and walleye CPUE was significant (P = 0.02). …

Go to article

The Effects Of Length, Weight, Age, And Gender On Mercury Concentrations In Burbot In North-Central Minnesota Lakes, Liam Hanley Jan 2024

The Effects Of Length, Weight, Age, And Gender On Mercury Concentrations In Burbot In North-Central Minnesota Lakes, Liam Hanley

Journal of Earth and Life Science

Burbot Lota lota in north-central Minnesota lakes have the potential to reach large sizes and consume large volumes of prey. This caveat may make burbot susceptible to higher rates of biocontamination, bioaccumulation and biomagnification. The objective of this study was to determine how changes in age, length, gender, weight, and lake affect total mercury concentrations in burbot. In this experiment 28 burbot were angled from three lakes: Cass (n = 17), Winnibigoshish (n = 4), and Bad Medicine (n = 7). Then tissue samples were taken from each fish and were lyophilized and homogenized. Homogenized tissue samples were analyzed by …

Go to article

Relationship Between Fishing Hours And Number Of Fish Harvested From Upper Red Lake, Dylan Ohlenkamp Jan 2024

Relationship Between Fishing Hours And Number Of Fish Harvested From Upper Red Lake, Dylan Ohlenkamp

Journal of Earth and Life Science

Total hours fishermen spend fishing and total amount of fish harvested per year are some of the most important pieces of knowledge gained from creel surveys. They provide crucial information that assesses fisheries mortality and pressure. MN DNR uses their results from creel surveys to improve or impose regulations, and to maintain healthy fisheries. Based on results from similar studies, there is expected to be a positive relationship between hours fished and fish harvested. To determine the relationship between these two variables on Upper Red Lake, data from two years were selected when the variables were at their highest and …

Go to article

A Guide To Otoliths Of Minnesota Fishes, Baylor J. Short Jan 2024

A Guide To Otoliths Of Minnesota Fishes, Baylor J. Short

Journal of Earth and Life Science

Investigations into the diet patterns of piscivores can provide crucial information on predator-prey relationships, population dynamics, and responses to changing ecosystems. However, digestive processes often remove or alter physical characteristics that are traditionally used to identify consumed fish. This problem has been addressed to some degree with advances in molecular technologies, although these methods can be costly and require specific training and equipment to do so. In contrast, bony structures such as otoliths, vertebrae, cleithra, and others frequently have morphologies that are unique among families, genera, and species. Because these structures are resistant to digestion, they can be used to …

Go to article

The Effect Of Triaenophorus Crassus On The Condition Of Coregonus Artedi, Alexander Surma Jan 2024

The Effect Of Triaenophorus Crassus On The Condition Of Coregonus Artedi, Alexander Surma

Journal of Earth and Life Science

Cisco Coregonus artedi is, historically, the largest commercial fishery in the Great Lakes. The species is also important to commercial and recreational fisheries in inland lakes. Tapeworm Triaenophorus crassus larvae embed themselves into the flesh of Ciscoes, rendering the fish unmarketable to humans. Triaenophorus crassus is common in inland waters such as Leech Lake and Cass Lake, MN. One Canadian researcher has suggested that the parasite negatively affects the growth and weight of Ciscoes. Poor condition can reduce fecundity, leading to lower recruitment rates. This would mean a detrimental impact on not only individual fish, but the health of …

Go to article

The Effects Of Parasitoid Wasps On The Intra- And Interspecific Competition Of Zaprionus Indianus, Camille R. Walsh-Antzak Jan 2024

The Effects Of Parasitoid Wasps On The Intra- And Interspecific Competition Of Zaprionus Indianus, Camille R. Walsh-Antzak

Honors Theses

Understanding the mechanisms underlying the success of biological invasions is essential to employ effective prediction and management strategies. The release of natural enemies in invaded regions (enemy release hypothesis) and increased competitive ability are major hallmarks of invasive species, however, these two processes are rarely studied within the same context. Here, we examined the role of ERH in influencing the competitive outcomes of an invasive insect pest, the African fig fly (Zaprionus indianus). In Virginia orchards, Z. indianus repeatedly outcompetes co-occurring drosophilid species. However, the mechanisms underlying the success of Z. indianus are poorly understood. Parasitoid wasps specializing in Camill …

Go to article

Cd46 Interaction With Adenovirus Type 64, A Causative Agent For Viral Pink Eye, Hanglin (Henry) Zhu Jan 2024

Cd46 Interaction With Adenovirus Type 64, A Causative Agent For Viral Pink Eye, Hanglin (Henry) Zhu

Honors Theses

Human adenovirus type 64 (Ad64) is a causative agent of contagious viral pink eye. We do not understand why Ad64 causes eye infections. One likely reason is the presence of a receptor molecule on the exposed surface of eye cells, but not other cells. Ad64 binds to a protein called CD46 on the cell surface. We aim to visualize how CD46 binds to the surface of Ad64. I mixed the extracellular portion of CD46 with purified Ad64 virus, then visualized it using negative stain transmission electron microscopy. In order to gain insight into how the virus binds CD46, we used …

Go to article

Assessing Evolution Of Reproduction Traits Along Seasonal Transitions And Latitudinal Gradients In An Invasive Species Of Fruit Fly, Zaprionus Indianus, Ansleigh Gunter Jan 2024

Assessing Evolution Of Reproduction Traits Along Seasonal Transitions And Latitudinal Gradients In An Invasive Species Of Fruit Fly, Zaprionus Indianus, Ansleigh Gunter

Honors Theses

This thesis examines the reproductive traits of Zaprionus indianus, an invasive species to the United States, to assess the possibility of rapid evolution. Significant differences in fecundity and diapause incidence have been seen in other Drosophilid fly species across the seasonal transition, from early to late season, and across the latitudinal gradient, from north to south. For this reason, fecundity, the reproductive ability of a female fly, and diapause incidence, a stress-induced reproductive arrest, were selected as variables of choice. Field collections and experiments revealed unexpected patterns in fecundity and diapause incidence, challenging initial hypotheses. While no significant differences in …

Go to article

Quantifying The Ecological Effects Of Salix Fragilis On Riparian Habitat In Kittitas County, Washington, Landon Shaffer Jan 2024

Quantifying The Ecological Effects Of Salix Fragilis On Riparian Habitat In Kittitas County, Washington, Landon Shaffer

All Master's Theses

Invasive species threaten plant community structure and function globally. Riparian areas, the zone near streams where water influences vegetation, are especially sensitive to invasive species colonization, suffering large-scale shifts in community composition. Salix fragilis (crack willow) is a nonnative riparian species abundant in the lower elevation tributaries of central Washington. Some speculate whether this willow should be listed as invasive in Washington, despite a lack of regional supporting evidence. I studied riparian communities dominated by either S. fragilis or native species in the Kittitas Valley and measured biodiversity, quantified differences in solar attenuation, and compared leaf decomposition rates to learn …

Go to article

University Biology Classrooms As Spaces For Anti-Racist Work: Instructor Motivations For Incorporating Race, Racism, And Racial Equity Content., Nicole L. Scheuermann, Candice Idlebird, Sayali Kukday, Vance J. Mccracken, Rachel E. Bradley, Heather E. Bergan-Roller Jan 2024

University Biology Classrooms As Spaces For Anti-Racist Work: Instructor Motivations For Incorporating Race, Racism, And Racial Equity Content., Nicole L. Scheuermann, Candice Idlebird, Sayali Kukday, Vance J. Mccracken, Rachel E. Bradley, Heather E. Bergan-Roller

Faculty Articles, Papers, and Other Scholarship

Science is often portrayed as a meritocratic endeavor, but university biology programs exhibit high rates of student attrition, particularly among students of Color, despite similar interest and aptitude for science, technology, engineering, and mathematics (STEM) as White students. Culturally relevant pedagogy is associated with student persistence in STEM. One way to practice culturally relevant pedagogy in biology courses is to engage students in discussions of race, racism, or racial equity. Guidance exists to help instructors incorporate race-related topics into the biology curriculum, but the reasoning behind the decision of whether to adopt this practice is not well characterized. Understanding instructors’ …

Go to article

How Does Marijuana Affect Reproductive Health?, Miriam Blatner Jan 2024

How Does Marijuana Affect Reproductive Health?, Miriam Blatner

The Science Journal of the Lander College of Arts and Sciences

Marijuana use has become prevalent worldwide, especially amongst men and women of reproductive age. Marijuana acts on Cannabinoid receptors, which are a part of the Endocannabinoid system. CB1 and CB2 receptors are most found in humans. Activation of Cannabinoid receptors in males cause a reduction in healthy sperm parameters and inhibits the acrosomal reaction, and therefore minimizes fertility potential. Researchers have not yet discovered any significant interactions between marijuana and the female reproductive system. There has also been limited evidence displaying the effects that marijuana has on pregnancy and breastfeeding of infants. Nevertheless, physicians have recommended against marijuana use while …

Go to article

Full Issue: Volume 17, Number 2, Spring 2024 Jan 2024

Full Issue: Volume 17, Number 2, Spring 2024

The Science Journal of the Lander College of Arts and Sciences

Complete .pdf file of Volume 17, Number 2 of The Science Journal of the Lander College of Arts and Sciences. Published Spring 2024.

Go to article

Targeting Vs. Modulating: How To Confront Variation In Cystic Fibrosis?, Yechiel Muller Jan 2024

Targeting Vs. Modulating: How To Confront Variation In Cystic Fibrosis?, Yechiel Muller

The Science Journal of the Lander College of Arts and Sciences

Cystic fibrosis is a genetic disease with over 2,000 reported mutation varieties. It affects a chloride channel called CFTR, which by the transmembrane transport of chlorine, maintains an apical membrane electrolyte equilibrium in luminal epithelial cells. Its malfunction results in cystic fibrosis which causes excess mucus in various organs and is associated with respiratory complications and salty sweat. Treatment of cystic fibrosis has primarily taken two approaches: a mutation-specific method, targeted at a particular mutation to restore its function, and a mutation-non-specific method, which modulates intracellular barriers to CFTR trafficking or cellular repression of mutant protein function. This paper presents …

Go to article

Sibo And The Effectiveness Of Treatment Via Diet And Medication, Elizabeth C. Hersko Jan 2024

Sibo And The Effectiveness Of Treatment Via Diet And Medication, Elizabeth C. Hersko

The Science Journal of the Lander College of Arts and Sciences

This study delves into small intestinal bacterial overgrowth (SIBO), exploring its origins, diagnosis, and treatment methods. The research illuminates the complexities of SIBO, a condition characterized by an abnormal surge of bacteria in the small intestine. Factors contributing to SIBO include impaired motility, anatomical abnormalities, and digestive system dysfunctions. Diagnosing SIBO proves challenging due to its nonspecific symptoms which often overlap with other conditions like irritable bowel syndrome (IBS). Various diagnostic approaches, including lactulose breath testing, blood tests, stool analysis, and imaging, aim to identify SIBO and its underlying causes. Treatment involves dietary modifications—such as low FODMAP, biphasic, or fast …

Go to article

Non-Surgical Treatment Options For Male-Pattern Baldness, Robert Schiffer Jan 2024

Non-Surgical Treatment Options For Male-Pattern Baldness, Robert Schiffer

The Science Journal of the Lander College of Arts and Sciences

Male pattern baldness affects nearly 50% of the world’s male population. It is associated with physiological conditions such as cardiovascular disease as well as psychological issues with self-image and self-esteem. Although surgical treatments exist, they are associated with risks and complications. Various non-surgical treatment modalities for male pattern baldness are available for patients. Topical and oral formulations of minoxidil, finasteride, and dutasteride can be used, in addition to low level light therapy (LLLT) and platelet rich plasma (PRP) therapy. As many treatment options exist, it may be challenging for patients to decide which to choose. Although there have been few …

Go to article

What Is Aphthous Stomatitis? What Are The Possible Causes And Treatments?, Shirah Balakhane Jan 2024

What Is Aphthous Stomatitis? What Are The Possible Causes And Treatments?, Shirah Balakhane

The Science Journal of the Lander College of Arts and Sciences

The historical understanding of Recurrent Aphthous Stomatitis (RAS), also known as canker sores, has evolved. This paper aims to collect data that determines the underlying factors that can cause RAS and highlights treatments or preventive measures one should take. RAS is a common mucosal disease of the mouth that affects healthy people and presents atypically in immunocompromised people. Geographical, age, and gender-related factors can all affect the prevalence. RAS still has no known cause; however, several systemic, local, immunologic, genetic, dietary, allergy, and microbiological factors—including immunosuppressive medications and stress—have been suggested as potential culprits. Using topical and systemic medicines, the …

Go to article

The Effects Of Electronic Cigarettes On The Oral Cavity, Batsheva Saposh Jan 2024

The Effects Of Electronic Cigarettes On The Oral Cavity, Batsheva Saposh

The Science Journal of the Lander College of Arts and Sciences

Electronic cigarettes, which became available for purchase in the United States in 2007, were initially touted as a harmless aid for smoking cessation. However, recent research into the impact of electronic cigarettes on the human body has shown potential deleterious effects. This paper aims to examine the effects electronic cigarette usage has on the oral cavity. The methods to compile research involved reading through many peer-reviewed articles to analyze the most current information on the topic. The findings indicate several potentially adverse effects on the oral cavity including oral cancer, periodontitis, dental caries, xerostomia, facial fractures, failed dental implants, and …

Go to article

Is Manual Therapy An Effective Modality Of Physical Therapy?, Caryn Karfunkel Jan 2024

Is Manual Therapy An Effective Modality Of Physical Therapy?, Caryn Karfunkel

The Science Journal of the Lander College of Arts and Sciences

Physical therapy provides relief to patients with musculoskeletal disorders who experience pain and have difficulty functioning. Manual therapy is one of the therapeutic modalities of physical therapy, and helps treat patients through utilizing human touch and pressure. This paper analyzes studies that aim to understand the reasoning behind manual therapy’s effectiveness as a physical therapy modality, questioning whether its benefits are primarily biomechanical or psychological. The research was conducted by analyzing relevant literature on academic databases on topics such as pain, physical therapy, manual therapy, and human touch. The findings reveal that manual therapy is an effective modality of physical …

Go to article

Ethanol-Containing Mouthwash: Is It Safe? Exploring The Potential Risks And Benefits, Michoel Adler Jan 2024

Ethanol-Containing Mouthwash: Is It Safe? Exploring The Potential Risks And Benefits, Michoel Adler

The Science Journal of the Lander College of Arts and Sciences

This thesis investigates the safety of ethanol-containing mouthwash, focusing on the risks and benefits associated with the ethanol in mouthwash and its metabolic product, acetaldehyde. While ethanol is an effective antimicrobial agent, its carcinogenic and cytotoxic effects raise some concerns. This paper examines ethanol and acetaldehyde exposure, its toxicity, and its effects on oral health. Existing studies have found risks associated with ethanol exposure and have not found decreased effectiveness in ethanol-free mouthwash controlling oral bacteria. Further research is needed to determine the exact risks associated with ethanol-containing mouthwash and should focus on identifying the most effective and safest combination …

Go to article

Is It Possible For Glp-1ras To Combat Type 2 Diabetes And Its Comorbidities?, Michael Weingarten Jan 2024

Is It Possible For Glp-1ras To Combat Type 2 Diabetes And Its Comorbidities?, Michael Weingarten

The Science Journal of the Lander College of Arts and Sciences

Type 2 Diabetes Mellitus is a prevalent metabolic disorder characterized by insulin resistance and pancreatic beta-cell dysfunction, leading to chronic hyperglycemia and comorbidities such as obesity and cardiovascular disease. Traditional treatments focus on glycemic control, but often fail to address the broader spectrum of related conditions. This study investigates the potential of glucagon-like peptide-1 receptor agonists (GLP-1RAs) to combat type 2 diabetes and its comorbidities through their diverse mechanisms of action. GLP-1RAs not only improve glycemic control by enhancing insulin secretion and inhibiting glucagon release, but also promote weight loss, reduce inflammation, and lower cardiovascular risk. The efficacy of GLP-1RAs …

Go to article

Overview Of Weight Loss Medications, Malky Mandel Jan 2024

Overview Of Weight Loss Medications, Malky Mandel

The Science Journal of the Lander College of Arts and Sciences

Obesity is a complex medical condition that is multifactorial in origin. About one-third of adults in the United States are obese, and another third are overweight (Ogden et al., 2007). Obesity is associated with a multitude of comorbidities, such as cardiovascular disease, diabetes mellitus, and osteoarthritis (Lim, Boster, 2023). Additionally, obesity may cause psychological disorders due to social prejudice and discrimination toward obese people (Wadden et al. 2002). Economically, obesity is also a tremendous financial burden (Tremmel et al. 2017). It is estimated that the overall cost of obesity-related illness in the US is nearly $500 billion (Cawley et al., …

Go to article

What Is The Best Way To Combat The Symptoms Of Knee Osteoarthritis?, Anna Reich Jan 2024

What Is The Best Way To Combat The Symptoms Of Knee Osteoarthritis?, Anna Reich

The Science Journal of the Lander College of Arts and Sciences

Osteoarthritis is a debilitating disease that a significant percentage of adults contend with. This degenerative joint disease causes the breakdown of tissue at the joint, which leads to symptoms of pain, decreased function, and limited range of motion. There are various methods of combating these symptoms. Treatment options include basic lifestyle modifications and other nonpharmacological methods, oral and topical drugs, intraarticular injections, and surgery. There are benefits and risks, as well as a lack of effectiveness associated with these treatments. The purpose of this paper is to determine whether there is an optimal treatment for this disease. Based on the …

Go to article

First Prev Next Last