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Articles 2881 - 2910 of 39096
Full-Text Articles in Biology
Designing A Novel Approach To Cadaveric Dissection And Evaluation Of The Lacrimal Gland Anatomy, Maresa Joanna Mcdowell
Designing A Novel Approach To Cadaveric Dissection And Evaluation Of The Lacrimal Gland Anatomy, Maresa Joanna Mcdowell
Doctoral Dissertations and Projects
During our study, the orbital dissections of 44 cadavers were analyzed, and the lacrimal gland's condition after dissection was evaluated. Medical students previously dissected twenty-two of the cadavers using the dissection steps outlined in Grant’s Dissector. From these, 21 student groups performed orbital dissection using the two approaches outlined in Grant’s Dissector. Post-evaluation of Grant’s anterior approach (GAA) showed that 50% of the lacrimal glands had signs of damage to the orbital lobe, and 88.89% of the palpebral lobe were damaged. When Grant’s supraorbital approach (GSA) was used, 70% of the palpebral lobes showed signs of damage compared to the …
Synthesis Of Zno: Zro2 Nanocomposites Using Green Method For Medical Applications, Mohammed J. Tuama, Maysoon F. Alias
Synthesis Of Zno: Zro2 Nanocomposites Using Green Method For Medical Applications, Mohammed J. Tuama, Maysoon F. Alias
Karbala International Journal of Modern Science
These days, nanocomposites are very popular, especially in medical applications. The spread of diseases in general, and those caused by microbes and cancerous diseases in particular, and the increased resistance of these diseases to antibiotics, have led to the need for the rapid, low-cost, and environmentally friendly production of nanocomposites. To create the chemical G-ZnO: ZrO2 and S-ZnO: ZrO2 (green technique), two different plant extracts were utilized: Z. officinal and S. aromaticum. The effective synthesis and acceptable properties features of the nanoparticles were confirmed using characterization techniques such as X-ray diffraction (XRD), Fourier transform infrared (FTIR) , diffuse reflectance spectroscopy …
Aging Drives Cd8 T Cells To Functional Extremes: From Non-Specific Cytotoxicity To Tissue-Mediated Exhaustion, Irina Shchukina
Aging Drives Cd8 T Cells To Functional Extremes: From Non-Specific Cytotoxicity To Tissue-Mediated Exhaustion, Irina Shchukina
Arts & Sciences Graduate Student Theses and Dissertations
CD8 T cells are a crucial component of the immune system, primarily responsible for executing the effector response against viral infections and cancer. Aging significantly impacts most immune cell types, with particularly dramatic changes observed in CD8 T cells. One major age-related difference is the marked decline in thymus activity, which leads to a substantial reduction in naive CD8 T cells and an increased abundance of memory CD8 T cells. Furthermore, recent work from our lab demonstrated that while young memory CD8 T cells are relatively homogeneous, memory CD8 T cells diverge into two subpopulations: PD1- memory CD8 T cells …
Aging Drives Cd8 T Cells To Functional Extremes: From Non-Specific Cytotoxicity To Tissue-Mediated Exhaustion, Irina Shchukina
Aging Drives Cd8 T Cells To Functional Extremes: From Non-Specific Cytotoxicity To Tissue-Mediated Exhaustion, Irina Shchukina
Arts & Sciences Graduate Student Theses and Dissertations
CD8 T cells are a crucial component of the immune system, primarily responsible for executing the effector response against viral infections and cancer. Aging significantly impacts most immune cell types, with particularly dramatic changes observed in CD8 T cells. One major age-related difference is the marked decline in thymus activity, which leads to a substantial reduction in naive CD8 T cells and an increased abundance of memory CD8 T cells. Furthermore, recent work from our lab demonstrated that while young memory CD8 T cells are relatively homogeneous, memory CD8 T cells diverge into two subpopulations: PD1- memory CD8 T cells …
Exploring Genetic Elements Related To The Co-Occurrence Of Crohn’S Disease And Rheumatoid Arthritis, Vamsi Korisapati, Karam Asad, Andrew T. Ozga
Exploring Genetic Elements Related To The Co-Occurrence Of Crohn’S Disease And Rheumatoid Arthritis, Vamsi Korisapati, Karam Asad, Andrew T. Ozga
Mako: NSU Undergraduate Student Journal
Crohn’s disease (CD) is a rare inflammatory bowel disease that negatively impacts the lining of the digestive tract, while Rheumatoid Arthritis (RA) is an autoimmune disorder wherein the body attacks healthy cells, also causing inflammation. The primary cause of inflammation in both diseases is an overactive immune response, but patients who are diagnosed with RA are typically prescribed nonsteroidal anti-inflammatory drugs, which is not a suggested method for treating CD. Here we do a literature survey through PubMed to uncover genetic variants common to both diseases and highlighted four shared genes: HLA-DRB1, NOD2, CARD9, and CXCL10. We then examined these …
Cytotoxic Potential Of Fungi In The Genus Ganoderma, Abril Chao, Omobolanle A. Ayangade, Braham Dhillon, Navi Gill
Cytotoxic Potential Of Fungi In The Genus Ganoderma, Abril Chao, Omobolanle A. Ayangade, Braham Dhillon, Navi Gill
Mako: NSU Undergraduate Student Journal
Ganoderma lucidum is a mushroom forming fungus that has been used in traditional Chinese medicine for over 2,000 years. G. lucidum, also known as lingzhi or reishi, is consumed in several Asian cultures to promote health and longevity. Bioactive molecules with anticancer properties have been isolated and characterized primarily from the species Ganoderma lucidum, and the cytotoxic potential of other species in the genus Ganoderma remains relatively unclear. Bioactive molecules isolated from mushroom fruiting bodies are demonstrated to have cytotoxicity against different cancer cell lines. Triterpenes and polysaccharides are the two major groups of compounds that exhibit antitumor and anti-inflammatory …
Mechanisms Of Uropathogenic E. Coli Reservoir Formation In The Gastrointestinal Tract, Philippe Nimma Azimzadeh
Mechanisms Of Uropathogenic E. Coli Reservoir Formation In The Gastrointestinal Tract, Philippe Nimma Azimzadeh
Arts & Sciences Graduate Student Theses and Dissertations
Urinary tract infections (UTI) are an extremely common affliction affecting 150 million people worldwide each year. UTIs are a leading cause of antibiotic therapy among otherwise healthy adult women, accounting for 15% of all outpatient antibiotic prescriptions. Uropathogenic Escherichia coli (UPEC) cause over 80% of community-acquired UTIs. Even when infection is cleared from the urine by clinical antibiotic regimens, 27% of women will experience recurrent UTI (rUTI) within months. Greater than 60% of rUTIs are caused by the same strain of E. coli that caused the initial infection, suggesting that one or more host-associated reservoirs of UPEC can re-inoculate the …
Mechanisms Of Uropathogenic E. Coli Reservoir Formation In The Gastrointestinal Tract, Philippe Nimma Azimzadeh
Mechanisms Of Uropathogenic E. Coli Reservoir Formation In The Gastrointestinal Tract, Philippe Nimma Azimzadeh
Arts & Sciences Graduate Student Theses and Dissertations
Urinary tract infections (UTI) are an extremely common affliction affecting 150 million people worldwide each year. UTIs are a leading cause of antibiotic therapy among otherwise healthy adult women, accounting for 15% of all outpatient antibiotic prescriptions. Uropathogenic Escherichia coli (UPEC) cause over 80% of community-acquired UTIs. Even when infection is cleared from the urine by clinical antibiotic regimens, 27% of women will experience recurrent UTI (rUTI) within months. Greater than 60% of rUTIs are caused by the same strain of E. coli that caused the initial infection, suggesting that one or more host-associated reservoirs of UPEC can re-inoculate the …
Systematic Review On Isolation, Purification, Characterization, And Industrial Applications Of Thermophilic Microbial Α- Amylases, Rugaiyah A. Arfah, Sarlan Sarlan, Abdul Karim, Anita Anita, Ahyar Ahmad, Paulina Taba, Harningsih Karim, Siti Halimah Larekeng, Dorothea Agnes Rampisela, Rusdina Bte Ladju
Systematic Review On Isolation, Purification, Characterization, And Industrial Applications Of Thermophilic Microbial Α- Amylases, Rugaiyah A. Arfah, Sarlan Sarlan, Abdul Karim, Anita Anita, Ahyar Ahmad, Paulina Taba, Harningsih Karim, Siti Halimah Larekeng, Dorothea Agnes Rampisela, Rusdina Bte Ladju
Karbala International Journal of Modern Science
The α-amylase enzyme, sourced from diverse organisms, including plants, animals, and bacteria, plays a crucial role in multiple industries, notably food processing sectors like cakes, fruit juices, and starch syrup. Research identifies thermophilic organisms as prime sources of this enzyme thriving at temperatures ranging from 41°C to 122°C. The enzyme purification was carried out using liquid-liquid extraction, which involved the exchange of substances between two liquid phases that were immiscible or partially soluble. The optimal temperature for α-amylase was 45 to 90°C. The best pH for bacterial and fungal α-amylases ranged from 5.0 to 10.5 and 5.0 to 9.0. Based …
Utilizing Lentinula Edodes And Pleurotus Ostreatus To Decrease Saccharomyces Cerevisiae Growth With Oxidative Stress Present As A Model For Cancer, Abdullah Amir
Journal of the South Carolina Academy of Science
Cancer is the second leading cause of death in the United States, and its effects can be worsened when high levels of oxidative stress are present. Lentinula edodes and Pleurotus ostreatus are two edible mushroom species that have been shown to contain many anticancer agents. However, the effects of these mushrooms have not been tested on cancer in the presence of oxidative stress. Therefore, the purpose of the present study was to test the effectiveness of L. edodes and P. ostreatus in reducing Saccharomyces cerevisiae growth when oxidative stress was present. It was hypothesized that these two mushroom species would …
Investigating The Synergistic Antibacterial Effects Of Ulva Lactuca And Fucus Vesiculosus Extracts On The Growth Of Staphylococcus Epidermidis, Bryan Lee
Journal of the South Carolina Academy of Science
This study investigates the antibacterial properties of extracts from marine macroalgae, Ulva lactuca (green algae) and Fucus vesiculosus (brown algae), individually and in combination, with a focus on combating antibiotic-resistant pathogens. The escalating challenge of antibiotic resistance requires the exploration of alternative antimicrobial agents derived from natural sources. Utilizing the agar well diffusion method, the study evaluates the inhibitory effects of the algae extracts on Staphylococcus epidermidis. Chloramphenicol serves as the positive control, while 5% dimethyl sulfoxide acts as the negative control. The combination of Ulva lactuca and Fucus vesiculosus extracts did not exhibit a significantly greater antibacterial effect than …
A Comparative Study To Predict Ovarian Cancer, Binadie Wickramasinghe, Gloria Regisford
A Comparative Study To Predict Ovarian Cancer, Binadie Wickramasinghe, Gloria Regisford
Journal of the South Carolina Academy of Science
Ovarian cancer is considered the fifth most common cancer type among females in the United States. Furthermore, ovarian cancer accounts for 25% of all gynecologic cancers, and usually, this cancer is diagnosed at a late stage. A patient can live at least five years longer if ovarian cancer is diagnosed early. Therefore, the early diagnosis of ovarian cancer is essential. This study aims to classify ovarian cancer using biomarkers such as ovarian cancer antigen (CA125), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), human epididymis protein 4 (HE4), and anti-TP53 antibodies. Rising or persistent CA125 blood levels provide a highly …
Cortisol And Alpha-Synuclein Stability In Saliva Under Varying Storage And Handling Conditions, Mo Zheng, Sujata Srikanth, Jeremiah Carpenter, Delphine Dean
Cortisol And Alpha-Synuclein Stability In Saliva Under Varying Storage And Handling Conditions, Mo Zheng, Sujata Srikanth, Jeremiah Carpenter, Delphine Dean
Journal of the South Carolina Academy of Science
Parkinson’s disease (PD) is a progressive neurodegenerative disorder characterized by motor impairments and non-motor symptoms, significantly impacting patients' quality of life. Currently, cerebrospinal fluid (CSF) is the primary biofluid used for PD biomarker studies, notably α-synuclein, despite the invasive nature of lumbar puncture procedures. Recent work has shown that some of these PD biomarkers have been measured in saliva. As an alternative to CSF, saliva can be non-invasively self-collected by patients repeatedly over time to monitor biomarker levels. However, the stability of these biomarkers in saliva needs to be evaluated before saliva can be considered for patient self-collection studies. Therefore, …
Table Of Contents
Journal of the South Carolina Academy of Science
No abstract provided.
The Effect Of Different Vegetable Oils (Macadamia Nut Oil And Walnut Oil) On The Coefficient Of Friction As A Finish For Oak Wood, Lee Dillon
Journal of the South Carolina Academy of Science
Slipping due to insufficient friction with flooring can cause fatal injuries in workplaces and homes. Oak wood flooring is commonly used in construction to build these environments. In the manufacturing process, wood finishing is conducted at the end of the process to strengthen the properties and longevity of the wood, although it could impact the coefficient of friction (COF) causing slip falls. Vegetable oils, such as macadamia nut and walnut oils, used as wood finishes have gained prominence due to their beneficial aspects to the environment. However, little is known about their effectiveness as a safe coating for wood floors. …
Prokaryotic Inhabitants Of Hypersaline Brines From Former Salt Mine In Solivar (Presov, Slovakia), Shivani Adhvaryu, Maria Piknova, Lea Nosalova, Lenka Malinicova, Sona Brestovicova, Jana Kiskova, Mariana Kolesarova, Peter Pristas
Prokaryotic Inhabitants Of Hypersaline Brines From Former Salt Mine In Solivar (Presov, Slovakia), Shivani Adhvaryu, Maria Piknova, Lea Nosalova, Lenka Malinicova, Sona Brestovicova, Jana Kiskova, Mariana Kolesarova, Peter Pristas
FRONTIERS UNBOUND: Exploring Extreme Environments
No abstract provided.
Systematics Of The Rhinolophus Landeri Complex, With Evidence For 3 Additional Afrotropical Bat Species, Bruce D. Patterson, Terrence C. Demos, Laura Torrent, Amanda L. Grunwald, Cecilia Montauban, Julian C. Kerbis Peterhans, Molly M. Mcdonough, Carl W. Dick, Michael Bartonjo, M. Corrie Schoeman, Multiple Additional Authors
Systematics Of The Rhinolophus Landeri Complex, With Evidence For 3 Additional Afrotropical Bat Species, Bruce D. Patterson, Terrence C. Demos, Laura Torrent, Amanda L. Grunwald, Cecilia Montauban, Julian C. Kerbis Peterhans, Molly M. Mcdonough, Carl W. Dick, Michael Bartonjo, M. Corrie Schoeman, Multiple Additional Authors
Biology Faculty Publications and Presentations
Roughly a third of all horseshoe bat species (Rhinolophidae: Rhinolophus) are found in Africa, where a recent continent-wide genetic survey suggested the presence of both undescribed and apparently invalid species. Here, we focus on the R. landeri species complex and the recent elevation of R. lobatus Peters, 1852, to species rank. That action created ambiguity in the taxonomy of East African members of the group—are both R. landeri Martin, 1838, and R. lobatus sympatric in East Africa or is another, unnamed species present there? Here, we refine genetic, morphological, and behavioral characterizations of R. landeri and its erstwhile synonyms with …
Assessing Two Methodologies To Protect Stored Rice From Insect Infestation, Md Naim Uddin
Assessing Two Methodologies To Protect Stored Rice From Insect Infestation, Md Naim Uddin
Student Theses and Dissertations
Rice can be infested with various insects during storage. Long-lasting insecticide netting (LLIN) can be a good barrier for insects if LLIN can be employed to air vents in rice mills. However, accumulated dust from milling practices could impact LLIN efficacy. Two experiments were conducted, in one experiment, lesser grain borer (LGB), Rhyzopertha dominca (F.) (Coleoptera: Bostrichidae) exposed to LLIN for 1 and 10 min and assessed mortality after 1 h and 1 week. In another experiment, maize weevil (MW), Sitophilus zeamais [Motschulsky (Coleoptera: Curculionidae)] exposed to the same LLIN and examined knockdown after 24 h. LLIN demonstrated higher mortality …
Montane Molluscs: Factors Affecting Snails And Their Trematodes Throughout The Mountain Regions Of Arkansas, Taylor Michelle Fiedor
Montane Molluscs: Factors Affecting Snails And Their Trematodes Throughout The Mountain Regions Of Arkansas, Taylor Michelle Fiedor
Student Theses and Dissertations
Spatial processes across both broad and fine scales are important for understanding ecosystem function. Broad-scale spatial processes can be defined as elevational, latitudinal, or longitudinal processes whereas fine-scale spatial processes represent movement and dispersal among habitat patches. Historically, studies on freshwater snail distributions have focused on fine-scale processes with secondary consideration given to spatial sampling. Species inventories for freshwater snails are outdated because historically snail species descriptions were based on shell morphology, which is highly plastic. In Arkansas, it is estimated that there are 36 freshwater snail species, but this estimate does not account for shell plasticity and does not …
Elevating Microrna Levels By Targeting Biogenesis With Steric-Blocking Antisense Oligonucleotides, Mallory A. Havens, Anthony J. Hinrich, Frank Rigo, Michelle L. Hastings
Elevating Microrna Levels By Targeting Biogenesis With Steric-Blocking Antisense Oligonucleotides, Mallory A. Havens, Anthony J. Hinrich, Frank Rigo, Michelle L. Hastings
Biology Department Faculty Articles
MicroRNAs (miRNAs) are regulators of gene expression, and their dysregulation is linked to cancer and other diseases, making them important therapeutic targets. Several strategies for targeting and modulating miRNA activity are being explored. For example, steric-blocking antisense oligonucleotides (ASOs) can reduce miRNA activity by either blocking binding sites on specific mRNAs or base-pairing to the miRNA itself to prevent its interaction with the target mRNAs. ASOs have been less explored as a tool to elevate miRNA levels, which could also be beneficial for treating disease. In this study, using the PKD1/miR-1225 gene locus as an example, where miR-1225 is located …
Genotypic And Phenotypic Characterisation Of Asymptomatic Bacteriuria (Abu) Isolates Displaying Bacterial Interference Against Multi-Drug Resistant Uropathogenic E. Coli, Ciara Kenneally, Craig P. Murphy, Roy D. Sleator, Eamonn P. Culligan
Genotypic And Phenotypic Characterisation Of Asymptomatic Bacteriuria (Abu) Isolates Displaying Bacterial Interference Against Multi-Drug Resistant Uropathogenic E. Coli, Ciara Kenneally, Craig P. Murphy, Roy D. Sleator, Eamonn P. Culligan
Department of Biological Sciences Publications
Escherichia coli can colonise the urogenital tract of individuals without causing symptoms of infection, in a condition referred to as asymptomatic bacteriuria (ABU). ABU isolates can protect the host against symptomatic urinary tract infections (UTIs) by bacterial interference against uropathogenic E. coli (UPEC). The aim of this study was to investigate the genotypic and phenotypic characteristics of five ABU isolates from midstream urine samples of adults. Comparative genomic and phenotypic analysis was conducted including an antibiotic resistance profile, pangenome analysis, and a putative virulence profile. Based on the genome analysis, the isolates consisted of one from phylogroup A, three from …
Biology Department Publications: 2014, Sam Lindgren
Biology Department Publications: 2014, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2014. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2017, Sam Lindgren
Biology Department Publications: 2017, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2017. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2009, Sam Lindgren
Biology Department Publications: 2009, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2009. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Synergistic Inhibition Of Hiv-1 Regulatory Function Using A Dual Expression Shrna Plasmid, Christine Sanderson, William H. Jackson
Synergistic Inhibition Of Hiv-1 Regulatory Function Using A Dual Expression Shrna Plasmid, Christine Sanderson, William H. Jackson
Journal of the South Carolina Academy of Science
HIV infection of CD4+ T Helper lymphocytes results in a gradual loss of immune competence, which ultimately leads to development of the acquired immune deficiency syndrome (AIDS). HIV-1 expresses two regulatory proteins, Tat and Rev, which act to upregulate viral transcription and facilitate mRNA transport enhancing the rate of translation. Inhibition of Tat and Rev have been shown to block virus replication. Therefore, Tat and Rev represent critical key points in the virus replication cycle. This study investigated the potential of RNA interference (RNAi) to inhibit these proteins using short hairpin RNAs (shRNAs). For this, plasmids expressing shRNAs targeting …
Biology Department Publications: 2005, Sam Lindgren
Biology Department Publications: 2005, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2005. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2011, Sam Lindgren
Biology Department Publications: 2011, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2011. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2007, Sam Lindgren
Biology Department Publications: 2007, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2007. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2022, Sam Lindgren
Biology Department Publications: 2022, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2022. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.
Biology Department Publications: 2018, Sam Lindgren
Biology Department Publications: 2018, Sam Lindgren
Biology Department Bibliographies
This document is a noncomprehensive list of publications made by graduate students, post-doctoral researchers, and faculty members in the Biology Department in 2018. It indexes those publications available through major databases, and serves as an archival record of the Department’s robust scholarly contributions.