Biochemical and Biomolecular Engineering Commons^™

Dissolution Mechanism Of Nonionic Polyether Surfactants In Supercritical Co2, Ning Xu, Yanling Wang, Baojun Bai, Shizhang Cui, Zan Gao, Yu Zhang, Di Li, Wenjing Shi, Wenhui Ding, Peixu Ma

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Polyoxyethylene ether is an efficient CO₂-philic compound with significant potential applications in CO₂ flooding, which requires CO₂-philic surfactants with high solubility in supercritical CO₂ (scCO₂). This study elucidates the molecular and atomic-level dissolution mechanism of the fatty alcohol polyoxyethylene ether (AEO) in scCO₂ by combining phase-behavior experiments and molecular dynamics simulations. The solubility of AEO in scCO₂ is measured using a semiconductor laser. AEO containing three polyoxyethylene (EO) groups exhibited the highest solubility in scCO₂.The solubility of AEO in scCO₂ decreased with an increase in the number …

Cultivation Of Botryococcus Braunii For The Production Of Hydrocarbons Suitable For Fuel Use, Bryan C. Carroll

All Theses

Energy security, rural poverty, and climate change are pressing issues of our time. Biofuels provide a solution to these issues, with a focus on sustainable aviation fuel, SAF, due to compatibility with aircraft infrastructure and energy density. This research aims to review and produce knowledge about a specific microalga, Botryococcus braunii, for its potential for SAF. First a literature review on the process was conducted followed by an experimental study on the impact of aqueous media and inorganic carbon its growth and hydrocarbon content. The literature review found the process consists of cultivation followed by lipid extraction or hydrothermal …

Impact Of Cysteine And Tyrosine Dipeptides On Cho Cell Performance In A Perfusion Mimic, Corrin L. Pruitt

All Theses

Perfusion cell cultures typically achieve higher cell densities and generate higher volumetric productivities than fed-batch cultures due to continuous nutrient supply and spent media removal. Despite these advantages, perfusion cell cultures remain underutilized for licensed product manufacturing, primarily due to the lack of small-scale perfusion models for high-throughput process development and the complexities involved in media formulation capable of supporting high cell densities during long-term continuous operation. To avoid nutrient limitation at high cell densities, current perfusion processes rely on using higher perfusion rates, which results in significant media wastage and downstream product dilution. Therefore, there has been an effort …

Gallium-Containing Bioactive Glasses: Their Influence On Ion Release And The Bioactivity Of Resulting Glass Polyalkenoate Cements, Lana Margaret Placek, Danielle Lee Perry, Mark Robert Towler, Anthony William Wren

Chemical and Biochemical Engineering Faculty Research & Creative Works

A series of glasses (0.48SiO2 − [0.40-x]ZnO − 0.12CaO-xGa2O3, x = 0, 0.8, 0.16) was developed to formulate a series of Ga-containing glass polyalkenoate cements (GPCs). The solubility of GPCs was tested using DI water, and it was found that the sample containing the highest mol% of Ga, LGa-2, had the most Ga ion release. The GPCs were incubated in SBF, and SEM/EDS analysis revealed that the at% of P increased, while the at% of Si decreased, highlighting the CaP precipitation on the GPC surface. The at% of Ga also decreased, reinforcing the Ga release from the GPC. Cellular testing …

Development And Experimental Validation Of A Non-Invasive Blood Group Detection System, Nurath K. Nurudini

Tanzania Journal of Engineering and Technology (TJET)

An individual's blood group consists of red blood cell antigens whose composition is determined by protein presence, antigen structure, and gene series. Persons aged above six months have significant anti-A and/or anti-B in their serum. During transplantation and transfusion, ABO blood group identification is the most essential factor. The conventional method involves drawing blood samples from patients, and the blood group is determined based on the antigen-antibody reaction. This method consists of adding chemical reagents. However, this requires time of operation, and throughput analysis is high, and the process is also challenging to interpret. Accurate and rapid identification of blood …

Reduction Of Volatile Acidity Of Grape Wines By Immobilized Lipase, Azamhon Kh. Khasanov, Barno A. Abdullaeva, Xasan T. Khasanov

CHEMISTRY AND CHEMICAL ENGINEERING

The aim of this work is to study the enzymatic transformation of acetic acid into ethyl acetate by immobilized lipases of the fungus Rhizopus microsporus UzLT-1 obtained on the basis of silica gel and phosphatidylethanolamine to reduce the content of volatile acids in grape wines. In the work, a preparation of lipase from the fungus Rhizopus microspores was used. Lipolytic activity was measured by photocolorimetric method using rhodamine 6G as a chromophore agent. The catalytic property of lipolytic enzymes from the fungus Rh.microsporus immobilized on the surface of silica gel coated with polyamides and modified cephalin in aqueous-alcoholic media was …

Investigation Of Retention And Dehydration Of Preformed Particle Gel For Conformance Control In Fractured Carbonates, Abdulaziz A. Almakimi, Abdullah O. Almansour, Junchen Liu, Baojun Bai, Ibnelwaleed A. Hussein

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Preformed particle gel (PPG) treatment has proved to be among the most effective methods to reduce excessive water production in fractured reservoirs. The blocking ability of PPGs to fractures or fracture-like features is highly dependent on injected gel properties and volume. Gel dehydration during extrusion through fracture is common and has a considerable effect on gel properties, transport, and plugging efficiency. As the gel particles propagate through the fracture, continuous dehydration is often associated and causes the gel to concentrate and require high-pressure gradients to move. Dehydration might be desirable to a certain limit because it can help to form …

Interfacial Phenomena Of Plastics: From Surface Modifications To Environmental Impacts, Kennedy Guillot

LSU Doctoral Dissertations

Plastic is a ubiquitous part of everyday life since its introduction in the previous century. Global production continues to exponentially increase, establishing plastics as one of the most dominant materials in modern manufacturing. Within the scope of academia, plastic is essential due to its low cost and sterility, particularly for minimizing contamination. Beyond the laboratory, plastic use spans numerous industries, and its use and disposal has since raised many environmental concerns. Once valued for its durability, plastics now pollute the environment in landfills and natural ecosystems. In recent decades, the consequences of this pollution have been investigated, yet the full …

Adaptive Noise Estimation And Denoising With Deep Learning For Nmr Spectroscopy, Naveen Asokan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful analytical technique widely used for molecular structure elucidation in chemistry, biology, and medicine. However, spectral accuracy is often degraded by noise—particularly in low acquisition time settings—resulting in reduced resolution and obscured chemical features. While traditional noise reduction techniques such as signal averaging can improve spectral quality, they require longer acquisition times, limiting their utility in real-time and high-throughput applications.

This thesis presents a deep learning-based denoising framework designed to enhance the quality of complex-valued NMR spectra. The proposed model, built upon a U-Net architecture, incorporates both real and imaginary components of the …

Binary Solid/Liquid Equilibrium Of Mixtures Of Thermally Robust Salts And Molecular Compounds For Use As Heat Transfer Fluids, Jared Ridge Mathews

Poster Presentations

Fossil fuels, contributors to climate change that may bear catastrophic consequences, power the entire world. The human species is almost entirely dependent on fossil fuels for energy, but other sources of renewable and environmentally friendly energy must be developed. Concentrated solar power (CSP) is a promising source of renewable energy with hampered potential—better heat transfer fluids (HTFs) are needed for it to be economically feasible. Currently, the HTFs in industrial use are predominantly either synthetic oils or nitrate-based molten salts. Synthetic oils are only stable up to 400 °C, and molten salts often have high melting temperatures, making them prone …

Binary Solid/Liquid Equilibrium Of Mixtures Of Thermally Robust Salts And Molecular Compounds For Use As Heat Transfer Fluids, Jared Ridge Mathews

Honors Theses

Fossil fuels, contributors to climate change that may bear catastrophic consequences, power the entire world. The human species is almost entirely dependent on fossil fuels for energy, but other sources of renewable and environmentally friendly energy must be developed. Concentrated solar power (CSP) is a promising source of renewable energy with hampered potential—better heat transfer fluids (HTFs) are needed for it to be economically feasible. Currently, the HTFs in industrial use are predominantly either synthetic oils or nitrate-based molten salts. Synthetic oils are only stable up to 400 °C, and molten salts often have high melting temperatures, making them prone …

Engineering Affinity Of Yth Protein To M6a-Rna, Katelynn E. Horvath

Honors Scholar Theses

Engineered RNA-binding proteins (RBPs) show promise for diverse applications in research and therapeutic development. Modulating the interaction between YTH-domain containing proteins and methylated RNA ligands could result in a high affinity, highly specific binding protein for the advancement of research tools in neurodegenerative disease. N6-methyladenosine (m6A) modified RNA contributes to stress granule formation that promotes neurotoxicity in neurodegenerative disease, with concentrations of m6A-RNA increased fivefold in Alzheimer’s Disease. Further affinity maturation of the YTH-m6A interaction through directed evolution of the YTH domain could produce a novel protein with increased affinity better suited for the development of biological detection tools or …

Composition And Rich/Lean Loading-Dependent Density Measurements Of A Series Of Aqueous Ionic Amines For Co2 Capture, Claudia Nguyen

Honors Theses

As climate change worsens worldwide, there is a drive to develop more efficient and sustainable methods to mitigate its impact through carbon capture methods like carbon dioxide scrubbing. Carbon scrubbing directly captures carbon dioxide (CO2) emissions from industries or power plants before they are released into the environment. The CO2 captured can be utilized for various applications or can be stored underground. However, this method faces numerous challenges, such as the degradation of the solvent or corrosion of equipment. As a result, research has expanded to find a better medium to overcome these issues. In particular, aqueous ionic amines (AIA) …

Modeling Cell Buildup And Release In An Ultrafiltration Cartridge, Holiday B. Derosier

Chemical Engineering Undergraduate Honors Theses

While membrane filtration has improved greatly and has been incorporated into many modern practices, there isn’t much data on material exchange in and out of the lumen and how that effects the overall efficiency of the process. This data may help to accurately measure the reliability and efficiency of a filtration membrane system, which can lead to improvements in filtration sustainability, process lifespan, and product quality.

This project aims to model the material balance within a perfusion bioreactor ultrafiltration system in MATLAB, with a focus on bioreactors and cell buildup and release from the lumen. The results of this study …

Feasibility Of Liquid Carbon Sources For Algae Growth, Brady S. Jones

Chemical Engineering Undergraduate Honors Theses

This thesis explores the use of electrochemically produced aqueous bicarbonate as a novel liquid-phase carbon source for enhancing algal biomass productivity. Targeting the freshwater microalgae Chlorella Saccharophila, the study investigates its growth response to varying bicarbonate concentrations and compares the efficacy of liquid bicarbonate delivery with traditional gaseous CO₂ bubbling methods. Results demonstrate that Chlorella Saccharophila can sustain growth solely on bicarbonate, and that bicarbonate-fed cultures yielded higher biomass than those supplied with gaseous CO₂ or hybrid systems. These findings validate the potential of bicarbonate-based carbon delivery for scalable algae cultivation, offering key advantages such as gas-free operation, improved …

Development Of Translational Microscale Systems To Interrogate How Biophysical And Biochemical Cues Alter The Phenotype Of Hormone Positive Breast Cancer, Braulio Ortega Quesada

All Dissertations

Cancer is a complicated disease and one in every three diagnoses are women with breast cancer. Recent research shows that the progression of cancer depends strongly on interactions with other non-cancerous cells and non-cellular components. Metastasis, the spread of cancer to other parts of the body, is a key step in cancer progression and makes treatment harder, leading to poor response to treatments culminating in death in ~90% of patients. This dissertation focused on creating a series of microdevices as novel pre-clinical models of breast cancer. Two different devices were fabricated to (1) study how exposing cancer cells to the …

Cooperative And Bifunctional Ga-Ca-Cr2o3@Cao Structured Monoliths As Versatile Platform For Reactive Capture Of Co2 And Its Subsequent Conversion To Ethylene, Khaled Baamran, Ali A. Rownaghi

Chemical and Biochemical Engineering Faculty Research & Creative Works

Cooperative and bifunctional materials (BFMs) that integrate adsorbents and catalysts offer a promising strategy for the reactive capture of CO₂ to produce valuable fuels and chemicals. In this study, we developed structured BFMs via 3D printing that combine CaO as an adsorbent with Ga–Ca–Cr₂O₃ metal oxides as the catalyst for the reactive capture of CO₂ and its subsequent conversion to C₂H₄ via the oxidative dehydrogenation of C₂H₆ (CO₂-ODHE). Three different Ga–Ca compositions were used to modify the catalyst surface characteristics and enhance C₂H₄ selectivity. …

Influence Of Substrate Temperature On The Properties Of Reactive Dc Magnetron Co-Sputtered Ag-Doped Tio2 Thin Films, Hezekiah B. Sawa

Tanzania Journal of Engineering and Technology (TJET)

This study reports on the influence of substrate temperature on the properties of Ag-doped TiO2 thin films. The films were deposited by reactive DC co-sputtering of Ti and Ag targets at different substrate temperatures and Ag target sputtering powers. Grazing incident X-ray diffractometer confirmed that all films were polycrystalline with dominant peak oriented along (101) planes representing the anatase TiO2 phase. The average grain size of the samples improved with increase in deposition temperature. At a substrate temperature of 450 ℃, the samples had a dominant peak representing the rutile phase, suggesting partial transformation from anatase to rutile phase. The …

Production Of Potassium-Rich Biofertilizer From Composted Banana Peels And Watermelon Rinds, Neema O. Msuya

Tanzania Journal of Engineering and Technology (TJET)

This study investigated the production of biofertilizer from composted banana peels and watermelon rinds, focusing on the mineral content and its impact on plant growth. The process involved characterizing raw materials, producing biofertilizer, analyzing mineral concentrations (potassium, nitrogen and phosphorus), and evaluating its quality through Spiny Amaranth seed growth. A compost bin with three compartments was designed, testing three composting ratios of banana peels to watermelon rinds (2:1, 1:2 and 1:1). Composting was monitored on moisture content, pH, organic matter, and temperature for 37 days. The 1:1 ratio had the lowest temperature (33.45°C) and highest pH (7.08), while the 2:1 …

Enhancing Oil Recovery With Novel Nano-Particle-Infused Surfactant Biopolymer Composite: A Comprehensive Investigation, Attia Attia, Amira Shafaay Dr., Michael Sami Alfonse Eng., George Azmi Eng., Rania Ramadan

Petroleum Engineering and Gas

The oil industry worldwide is searching for a new way to increase oil recovery. Chemical flooding has been used worldwide to improve oil recovery. In this research, the study of Enhanced Oil Recovery was carried out by using an Egyptian oil of API 42◦; the experiments were done by using Xanthan biopolymer (XG) gum with sodium dodecylbenzene sulfonate (SDBS) as a composite for the EOR process and studying the impact of different composite concentrations on oil recovery. Design Expert software was used to determine the optimum concentrations of the composite. 500 ppm concentration of graphene cobalt samarium ferrite nanoparticles (NP) …