The Reveal: A Technical Study And Conservation Treatment Of An Overpaint Portrait, 2024 SUNY University at Buffalo
The Reveal: A Technical Study And Conservation Treatment Of An Overpaint Portrait, Camille Ferrer
Art Conservation Master's Projects
A severely damaged 19th-century oil painting depicting a portrait of a woman was treated at Patricia H. and E. Garman Art Conservation Department. A typed letter provided by the owner mentioned that it has been previously restored yet returned with unsatisfactory results. After further examination, the painting appeared to have been previously treated multiple times by different people. There was overpaint distinctly present on the face and later discovered to be present overall. The full state of condition of the painting was initially unknown due to the sum of the surface being overpainted. However, there were evidence of paint loss …
Highly Toxic Aβ Begets More Aβ, 2024 Clark University
Highly Toxic Aβ Begets More Aβ, Merc M. Kemeh, Noel Lazo
Chemistry
No abstract provided.
Excited State Processes In Radical Elaborated Platinum Donor-Acceptor Complexes, 2024 University of New Mexico
Excited State Processes In Radical Elaborated Platinum Donor-Acceptor Complexes, Sangita Paudel
Chemistry and Chemical Biology ETDs
Organo-transition metal complexes are being widely studied to understand their photophysical properties for their wide range of applications as efficient emitters in organic light emitting diodes (OLEDs), light emitting electrochemical cells (LEECs), etc. Cyclometalated organo-transition metal complexes such as cyclometalated square planar platinum(II) complexes are becoming suitable candidates for such applications because of their highly efficient luminescence. Understanding the excited properties of such complexes is useful in designing highly efficient and color tunable phosphors with desired excited state lifetimes. We aim to explore the influence of radical substituents on electronic structure, luminescence quantum efficiencies, and excited state lifetimes by synthesizing …
Tribocorrosion And Metal Release From Austenitic Stainless Steels 304 And 201 In Simulated Cassava Food Contact, 2024 Western University
Tribocorrosion And Metal Release From Austenitic Stainless Steels 304 And 201 In Simulated Cassava Food Contact, Robert Addai, Temitope E. Olowoyo, Thalia E. Standish, Jeffrey Daniel Henderson, Ubong Eduok, Yolanda Hedberg
Chemistry Publications
Cassava is the third most significant calorie source in the tropics. Its processing has changed from traditional methods to stainless steel processing machines. This study investigated the influence of cassava on metal release from two common stainless steels, ASTM 304 and 201, with and without friction, and on tribocorrosion (multianalytically) of 304. Cassava was relatively corrosive and hindered repassivation of the surface oxide of stainless steel, but it also acted as a lubricant against mechanical friction. The combined action of friction and cassava caused a significant increase in iron, chromium, nickel, and manganese release from the stainless steels (30–35- fold …
Spectroscopic Characterization, Dft Calculations, In Vitro Pharmacological Potentials, And Molecular Docking Studies Of N, N, O-Schiff Base And Its Trivalent Metal Complexes, 2024 University of South Africa
Spectroscopic Characterization, Dft Calculations, In Vitro Pharmacological Potentials, And Molecular Docking Studies Of N, N, O-Schiff Base And Its Trivalent Metal Complexes, Ikechukwu P. Ejidike, Amani Direm, Cemal Parlak, Adebayo A. Adeniyi, Mohammad Azam, Athar Ata, Michael O. Eze, Joshua W. Hollett, Hadley S. Clayton
Michigan Tech Publications, Part 2
In this study, trivalent metal complexes of the category: [M(L)(H2O)nCly] obtained from the interaction of metal3+ ion salts with organic N, N, O-Schiff base (HL) (where: HL = 4-{(Z)-((2-{(E)-((2-hydroxyphenyl)methylidene)amino}ethyl)imino)methyl}-2-methoxyphenol; n, y = 1 or 2 and M = Ti(III), Fe(III), Ru(III), Cr(III) and Al(III)) were synthesized and characterized viz molar conductance, FT-IR, and UV–Vis spectroscopies, elemental analyses, thermal analyses (TGA and DTA), and UV–Vis spectroscopy, theoretical calculations. A distorted octahedral structure around the metal ions was proposed based on the obtained experimental and calculated data. Thermal examination of the complexes signposts the step-by-step disintegration to give the final decomposition product …
Hydrothermal Synthesis Of (C5h14n2)[Cocl4]⸳0.5h2o: Crystal Structure, Spectroscopic Characterization, Thermal Behavior, Magnetic Properties And Biological Evaluation, 2024 University of Sfax
Hydrothermal Synthesis Of (C5h14n2)[Cocl4]⸳0.5h2o: Crystal Structure, Spectroscopic Characterization, Thermal Behavior, Magnetic Properties And Biological Evaluation, Sandra Walha, Noureddine Mhadhbi, Basem F. Ali, Abdellah Kaiba, Ahlem Guesmi, Wesam Abd El-Fattah, Naoufel Ben Hamadi, Mark M. Turnbull, Ferdinando Costantino, Houcine Naïli
Chemistry
The organic-inorganic compound (C5H14N2)[CoCl4]⸳0.5H2O, I, was characterized by various physicochemical techniques. The X-ray diffraction analysis revealed that the compound crystallizes in the centrosymmetric space group C2/c of the monoclinic system. The atomic arrangement the Co(II) complex is built from isolated [CoCl4]2– anions, 1-methylpiperazine-1,4-diium [C5H14N2]2+ cations and free water molecules. The crystal structure study showed that the cohesion of I is assured through N–H···Cl and N–H···O hydrogen bonds giving birth to a 3-D architecture. Hirshfeld surface analysis revealed that Cl···H/H···Cl and …
Purification And Isolation Of Α-Chloro-Β-Lactone Precursor Molecules, 2024 Bridgewater College
Purification And Isolation Of Α-Chloro-Β-Lactone Precursor Molecules, Matthew Ellis
Honors Projects
This research investigates the synthesis of α-chloro-β-lactone molecules, focusing on the production, isolation, and purification of two precursor compounds from chloroacetic acid and substituted benzaldehydes. While multiple methods were explored, including EDC, DIC, and DCC catalysis, DCC proved to be most effective in producing higher yields. However, challenges in purification arose due to the formation of byproducts, particularly with DCC, prompting further investigation for efficient extraction and purification techniques. DCC, however, shows a promising route for α-chloro-β-lactone synthesis, despite purification complexities.
Enabling More Efficient Solar Thermal Energy Production And Storage, 2024 University of South Alabama
Enabling More Efficient Solar Thermal Energy Production And Storage, Allan Wilson
Poster Presentations
Concentrated Solar Power (CSP) stores & transfers energy using a Thermal Energy Storage Fluid (EIA AEO 2022)
Development Of An Enhanced Sampling Workflow To Accelerate Molecular Docking With Sparse Biophysical Information, 2024 Western Kentucky University
Development Of An Enhanced Sampling Workflow To Accelerate Molecular Docking With Sparse Biophysical Information, Zachary Stichter
Masters Theses & Specialist Projects
Rapid docking of flexible biological macromolecules remains a significant open challenge in protein structure determination. While rigid docking is relatively simple with toolkits such as TagDock, a key obstacle to rapid flexible docking is the complexity and roughness of the free energy surface associated with protein conformational motion (often termed the many-minima problem), meaning conventional molecular dynamics methods do not effectively sample protein conformations near the interaction complex in accessible timescales. Methods such as metadynamics and replica exchange molecular dynamics exist to ameliorate this obstacle, yet these methods use nonphysical biases or random swaps to enhance sampling. In contrast, high …
X-Ray Fluorescence Analysis Of Historic Art Paint Pigments, 2024 Binghamton University
X-Ray Fluorescence Analysis Of Historic Art Paint Pigments, Sofia A. Stirpe, Juergen Thieme
Binghamton University Undergraduate Journal
Utilizing synchrotron radiation, X-ray fluorescence (XRF) microscopy enables researchers to deduce the elemental composition of paint pigments with a higher sensitivity and resolution than that of lab-based XRF instruments. With this information, art historians can date paintings by examining the elemental makeup of paint pigments and the time periods in which they were used. One painting, Christ and the Woman Taken in Adultery, has been duplicated by Pieter Brueghel the Younger and other artists, leading to confusion over which artworks are Brueghel masterpieces or copies by other artists. Art historian Maurizio Seracini, retaining a painting that could be assigned …
Enhancing The Antibiotic Properties Of Meropenem With Hydrophobic Ion-Pairing, 2024 Rowan University
Enhancing The Antibiotic Properties Of Meropenem With Hydrophobic Ion-Pairing, Krishna Paul, Bidhan Barua, Lark Perez
STEM Student Research Symposium Posters
Antibiotic Resistance is one of the most urgent global threat to humankind. Most antibiotics are hydrophilic in nature while proteins and peptides are lipophilic. Enhancing lipophilicity of the antibiotic by HIP can increase solubility of the drugs in human and improve antibacterial effect as well. We hypothesized that formation of a hydrophobic drug complex would change the physical properties of the antibiotic and enhance its antimicrobial activity.
Myoglobin Unfolding And Protein Stability With Tmg, 2024 Rowan University
Myoglobin Unfolding And Protein Stability With Tmg, Eustratios R. Kossis, Dimitra N. Kossis, Kristen Rass, Taha Shahbaz, Gregory A. Caputo, Timothy Vaden
STEM Student Research Symposium Posters
Myoglobin, a widely studied protein in biophysics, is a small, helical, and highly soluble protein that has been investigated for decades. Its heme prosthetic group facilitates easy analysis of its folding state through absorbance spectroscopy. Ionic liquids (ILs), particularly room-temperature ionic liquids or molten salts, have gained significant attention in the past 15- 20 years for their potential use in electrochemical devices. Recently, their biocompatibility has become a focal point in research, given that certain IL species can either stabilize or destabilize biomolecular structures. This study employs absorbance and fluorescence spectroscopy to examine how amino acid-based ILs, specifically tetramethyl guanidine …
Identifying V. Cholerae's Autoinducer To Manipulate Its Quorum Sensing, 2024 Rowan University
Identifying V. Cholerae's Autoinducer To Manipulate Its Quorum Sensing, Jason X. Tran, Daniel Palacio, Lark Perez
STEM Student Research Symposium Posters
• Vibrio cholerae is a gram-negative anaerobic bacteria that inhabits brackish or saltwater areas.
• Causative agent of cholera, which results in acute diarrhea and dehydration.
• Uses quorum sensing, a cell density dependent method of communicating with other bacteria and regulating its entire lifecycle of infection. (gene expression of functions such as biofilm formation, virulence, and more)
• Vibrio cholerae determines bacterial population based on the secretion of several signaling molecules called an autoinducer from others of their kind.
• Upon adequate accumulation, they can deactivate their virulence and begin to leave their host’s body to continue infecting other …
Thermal Destabilization Of Azurin By Fatty Acid Ionic Liquids, 2024 Rowan University
Thermal Destabilization Of Azurin By Fatty Acid Ionic Liquids, Brandon Burrell, Austin K. Clark, Achismita Dutta, Esha Prajapati, Sierra Cottle, Andrew Ogungimi, Justin Burrell, Timothy D. Vaden
STEM Student Research Symposium Posters
Azurin is a mixed-structure redox protein involved in bacterial denitrification. Previous studies have shown that azurin is destabilized by imidazolium chloride ionic liquids (ImCl ILs) that can form micelles in aqueous solution, likely by micellar encapsulation. In these ImCl ILs the micelles form from the imidazolium cations. A relatively new class of ionic liquids is fatty acid ionic liquids (FAILs), in which the anion is a fatty acid. In FAILs micelles can form from the fatty acid anions. This presentation presents the results of a thermal unfolding study of azurin in the presence of FAILs in solution. The FAILs tetramethylguanidinium …
Characterization Of Lysozyme Stability In The Presence Of Lonic Liquids, 2024 Rowan University
Characterization Of Lysozyme Stability In The Presence Of Lonic Liquids, Madison Scott, Ramzy T.M. Malak, Daniel Obeid, Chun Wu, Timothy Vaden, Gregory A. Caputo
STEM Student Research Symposium Posters
Hen egg white lysozyme (Lyz) has been a well studied model system in biophysical investigations for decades. The protein is a small, primarily helical, highly soluble protein that is both commercially available and easily accessible. lonic liquids (ILs), often referred to as room-temperature ionic liquids or molten salts, have garnered great interest in the last 15-20 years as potential components of electrochemical devices or applications. More recently, the biocompatibility of these molecules has developed an increased interest in the field, especially considering that some IL species can stabilize biomolecular structures while other ILs strongly destabilize 3D structures. In this study, …
Molybdenum Alkylidyne Complexes With Phenoxide Ligands For Alkyne Metathesis, 2024 Louisiana State University at Baton Rouge
Molybdenum Alkylidyne Complexes With Phenoxide Ligands For Alkyne Metathesis, Marvin L. Stewart Jr
LSU Doctoral Dissertations
Abstract
Alkyne metathesis is a powerful synthetic tool, which provides easy access to complex organic molecules in a single-step. It is a dynamic covalent reaction that scrambles alkynes, carbon-carbon triple bonds (C≡C). Molybdenum- or tungsten-alkylidyne (Mo≡C, W≡C) complexes are typically used as catalyst to cleave and reform alkyne bonds. Our goal has been to gain a deeper understanding of the intrinsic differences between functional ligands by the development of novel phenoxide ligands.
In chapter 2 we explore the detailed synthesis of novel phenoxide podand ligands in an effort to identify their mo-alkylidyne complexes. We were able to synthesize a variety …
Predictors Of Student Success In College-Level General Chemistry, 2024 Binghamton University
Predictors Of Student Success In College-Level General Chemistry, Elijah J. Engler, Clarice Ak Kelleher
Binghamton University Undergraduate Journal
Success in college-level general chemistry is important because it is a required course for many different STEM majors and student success in early STEM classes correlates with retention of students in STEM. Identifying factors associated with success and failure can give educators a better understanding of the warning signs to look out for in struggling students. This paper compares factors and behaviors with final grades in general chemistry courses at Binghamton University, including adjectives selected from a word bank (“valued,” “supported,” etc.), resources used, and opinion on group work as it relates to learning. Correlations were found between student adjective …
One-Pot Synthesis Green Zinc Oxide Nanoparticles Immobilized On Activated Carbon Derived From Pineapple Peel For Adsorption Of Pb(Ii), 2024 Research Centre for Applied Microbiology, National Research and Innovation Agency Republic of Indonesia, KST Samaun Sa-madikun, Bandung 40135, Indonesia
One-Pot Synthesis Green Zinc Oxide Nanoparticles Immobilized On Activated Carbon Derived From Pineapple Peel For Adsorption Of Pb(Ii), Vienna Saraswaty, Evyka Setya Aji, Ardi Ardiansyah, Ayu Hanifah, Nathania Puspitasari, Shella Permatasari Santoso, Sandy Budi Hartono, Chandra Risdian, Elsy Rahimi Chaldun, Henry Setiyanto
Karbala International Journal of Modern Science
The current study introduces a one-pot technique for synthesizing an environmentally benign and cheap composite adsorbent, namely ZnO-PPAC, for the adsorption of Pb(II). The designated adsorbent was prepared by incorporating green synthesized zinc oxide (ZnO) nanoparticles on activated carbon-derived from pineapple peel. The prepared adsorbents were characterized using XRD, SEM, EDS, FTIR, and BET techniques. The XRD pattern verifies that the ZnO was successfully synthesized and immobilized onto the PPAC in a one pot synthesis system. The surface areas of ZnOPPAC and PPAC adsorbents were 13.62 m2/g and 961.96 m2/g, respectively. The FTIR evaluation of the ZnO-PPAC adsorbent revealed several …
Modern Approaches To Treating Hospital Acquired Infections: An Overview Of Current Treatments Using Antibiotics And New Therapies Centered Around Photo-Activated Porphyrins, 2024 Liberty University
Modern Approaches To Treating Hospital Acquired Infections: An Overview Of Current Treatments Using Antibiotics And New Therapies Centered Around Photo-Activated Porphyrins, Meghan Johns
Senior Honors Theses
Annually, hospital-acquired infections (HAIs) affect hundreds of thousands of people in the U.S. and impose a great economic burden. The current problem is further exacerbated due to the failure of traditional treatment strategies considering the rise in antimicrobial resistance rates. Besides the fact that antimicrobial resistances complicates clinical treatment strategies, patients are also more vulnerable to secondary infections and complications from prolonged antibiotic use. As a result, research investigating novel treatment strategies for bacterial infections has recently increased. A strategy using porphyrin-based compounds is showing promise. Porphyrins and their derivatives have exhibited bactericidal effects against Gram-positive bacteria by the destruction …
Allylic Rearrangement In Nbs Bromination Reactions, 2024 Winona State University
Allylic Rearrangement In Nbs Bromination Reactions, Devann J. Harris, Bryanna L. Wichner
Research & Creative Achievement Day
The allylic bromination of alkenes using N-bromosuccinimide (NBS) is a useful and selective substitution reaction, in which bromine radicals abstract hydrogen from the alkene to form a resonance-stabilized radical intermediate. However, allylic rearrangement can be a consequence of the intermediate's two resonance structures. Some literature sources imply that NBS bromination gives only one major product from asymmetrical alkenes, e.g., 2-hexene and 2-heptene, even when they should form equally stable but non-equivalent resonance contributors. In this research, bromination of trans-2-hexene was performed using cyclohexane as the solvent, and the products were analyzed using GC-MS to determine if only one product, 4-bromo-2-hexene, …