Triple Pulse Amperometry: A Method Of Detection Of Carbohydrates And Alcohols For Liquid Chromatography , 2017 Iowa State University
Triple Pulse Amperometry: A Method Of Detection Of Carbohydrates And Alcohols For Liquid Chromatography , Scott Hughes
Application of a triple pulse waveform is described for the anodic detection of simple alcohols and carbohydrates at a platinum electrode. The execution of the waveform incorporates the cleaning and reactivation of the platinum electrode, by alternate anodic and cathodic polarization, with measurement of the faradaic signal for the analyte at the reduced electrode surface. The waveform is completed within 0.5-1.5 s and the sampled faradaic signal exhibits no decay with time as would be the case for amperometric detection at a constant applied potential. Calibration curves made by plotting -1/I vs. 1/C are linear. This ...
Engineering Fret Biosensors For Microrna Presence/Absence Analysis, 2017 Oregon State University
Engineering Fret Biosensors For Microrna Presence/Absence Analysis, Nicholas E. Larkey, Sean M. Burrows
Biomedical Engineering Western Regional Conference
No abstract provided.
Energetic Effects Of Hole Transporting Materials On The Performance Of Organometal Halide Perovskite Photovoltaic Cells, So Min Park
Theses and Dissertations--Chemistry
Efficient, inexpensive, lightweight and flexible solar cells are desired to help meet the world’s growing energy needs. Organometal halide perovskite (OMHP) photovoltaic (PV) cells have shown dramatic increases in solar cell efficiencies increase over the last 5 years. OMHP PV cells have attracted significant attention due to their broad absorption spectra, high electron and hole mobility, and low production cost. The interface between hole transporting layer (HTL) and perovskite thin films have a significant influence on charge transfer and overall solar cell performance. 2,2’,7,7’-tetrakis(N,N-di-p-methoxyphenylamine)9,9’-spirobifluorene (Spiro-OMeTAD) is a small molecule largely ...
Analysis Of Gold Nanoparticles And Their Use With Laser Desorption/Ionization Mass Spectrometry, 2017 University of Massachusetts - Amherst
Analysis Of Gold Nanoparticles And Their Use With Laser Desorption/Ionization Mass Spectrometry, Alyssa Marsico
Doctoral Dissertations May 2014 - current
Gold nanoparticles (AuNPs) have many unique properties that make them attractive for use in various biological applications. Laser desorption/ionization mass spectrometry (LDI-MS) has been used to monitor AuNPs in complex biological samples but there are still many ways in which AuNPs can be used with MS. In this dissertation, the use of AuNPs to assist in analyte ionization has been investigated. Their ability to enhance signal from biomolecules based on their surface chemistry, size, aggregation and method of deposition has been studied. The first use of an inkjet printer to create surfaces from which analytes can be sampled is ...
Gold Nanoparticle Biodistributions And Stability In Vivo From Mass Spectrometric Imaging, 2017 University of Massachusetts - Amherst
Gold Nanoparticle Biodistributions And Stability In Vivo From Mass Spectrometric Imaging, Sukru Gokhan Elci
Doctoral Dissertations May 2014 - current
Their smaller size, inherent non-toxicity and tunable properties of gold nanoparticles (AuNPs) attract researchers for their use in biological applications such as drug delivery, imaging and therapeutics. Understanding the in vivo fate of these AuNPs are essential for their potential effects in both the environment and the body. In this dissertation, mass spectrometric imaging methods using laser ablation inductively-coupled plasma mass spectrometry (LA-ICP-MS) and laser desorption/ionization (LDI-MS) have been investigated to monitor the in vivo fate of AuNPs. AuNP injected mouse tissue samples can be obtained and readily imaged to track the injected AuNPs using these methods. A first-ever ...
Ryan Caylor, 2016 Concordia University - Portland
Ryan Caylor, Ryan Caylor
Matthew E. Wise
Cole Crosby, 2016 Concordia University - Portland
Cole Crosby, Cole Crosby
Matthew E. Wise
Avery Hong, 2016 Concordia University - Portland
Avery Hong, Avery Hong
Matthew E. Wise
Preparation Of Derivatized Polyaniline For Biosensing Applications, 2016 Clark Atlanta University
Preparation Of Derivatized Polyaniline For Biosensing Applications, Tiana C. Shaw
Electronic Theses & Dissertations Collection for Atlanta University & Clark Atlanta University
Conducting polymers have emerged as a promising material for optoelectronics and chemical sensing application. Polyaniline (PANI) is a conductive polymer which can be easily functionalized to be specific for various biomolecules and has ideal sensor characteristics. The protonation and deprotonation of the polyaniline’s backbone by derivatization can result in color and conductive change responses. This makes it ideal for the construction of a real time, naked eye sensor. Derivatized polyaniline has previously been reported as a colorimetric sensor in solution. We plan to create a more practical sensor by synthesizing hydroxyl functionalized polyaniline thin films. In this study, we ...
Polyol Induced Partitioning Of Essential Oils In Aqueous Organic Solvent Mixtures, 2016 Seton Hall University
Polyol Induced Partitioning Of Essential Oils In Aqueous Organic Solvent Mixtures, Thomas Delmastro
Seton Hall University Dissertations and Theses (ETDs)
Polyol Induced Extraction (PIE) was developed and patented at Seton Hall University by Drs. John R. Sowa Jr., Wyatt R. Murphy, and Mithilesh Deshpande. It was originally discovered and implemented as a method to recycle and reuse waste acetonitrile during the production shortage in 2008. Through the use of PIE, a solvent mixture containing acetonitrile and water can be separated by employing a polyol mass separating agent, which induces a phase separation. The system is separated into its corresponding aqueous and organic phases, with the organic phase being a highly purified organic liquid. Based on the successful experimental results that ...
Development Of An F-Element Separation Chemistry Using Solid Electrolytes, 2016 University of Tennessee, Knoxville
Development Of An F-Element Separation Chemistry Using Solid Electrolytes, Kristian Guy Myhre
The f‒elements (lanthanides and actinides) have numerous applications and are critically important to many industries, including the energy, security, and medical industries. One of the barriers to increased use and availability of the f‒elements is the difficulty in separating them from each other due to their similar chemistries. This is especially true of the trivalent f‒elements (lanthanides and minor actinides). The development of separation techniques that maximize the differences in the physicochemical properties of the f‒elements is therefore an important area of research. For these reasons, an effort was undertaken to explore the use of solid ...
Graphene Quantum Dots Electrochemistry And Development Of Sensitive Electrochemical Biosensor [Hybrid Poster 1-B], 2016 Western Kentucky University
Graphene Quantum Dots Electrochemistry And Development Of Sensitive Electrochemical Biosensor [Hybrid Poster 1-B], Tyler Smith, Alexander Banaszak
Graphene quantum dots (GQDs) are zero-dimensional material derived from graphene derivatives with characteristics from the structure of graphene with quantum confinement and edge effects possessing unique properties. Intense research activity in GQDs is attributed to their novel physical-chemical phenomena arising from the sp2-bonded carbon core surrounded with edge functional moieties. In this work, GQDs of optimal 5-7 nm size are investigated for their fundamental electrochemical properties and use in electrochemical sensing including enzyme-based glucose biosensor. Glucose oxidase (GOx) was immobilized on GQDs modified glassy carbon (GC) and the UV-Vis absorption and fluorescence spectroscopy, electron microscopy, cyclic and ...
P-26 Detection Of Counterfeit Antimalarial Drugs By Sers, 2016 Andrews University
P-26 Detection Of Counterfeit Antimalarial Drugs By Sers, Getahun Merga, P. Shepard, M. Trujillo, J. Camden
Celebration of Research and Creative Scholarship
Substandard antimalarial drugs are a major problem to the health of citizens in developing countries, and it is likely that the problem persists due to the lack of means to detect substandard drugs. Various colorimetric techniques have been implemented to determine if a drug contains the stated active ingredient or not, but vibrational spectroscopies such as NIR and Raman can be used to more reliably quantify the amount of active ingredient. The use of Raman, however, has been limited by the presence of significant sample fluorescence that interferes with detection of the SERS signals of the active ingredients. Thus, we ...
Quantitative Analysis Of Acetylsalicylic Acid By Q-Nmr (Quantitative-Nuclear Magnetic Resonance Spectroscopy), 2016 Governors State University
Quantitative Analysis Of Acetylsalicylic Acid By Q-Nmr (Quantitative-Nuclear Magnetic Resonance Spectroscopy), Charles Flemming Jr.
All Student Theses
Quantitative analysis is an important step during pharmaceutical drug development. Currently, the pharmaceutical industry uses high performance liquid chromatography (HPLC) for quantitative analysis of organic compounds as the preferred technique. The proton nuclear magnetic resonance (NMR) technique has an inherent ability to quantify a given analyte and may be used to quantify organic compounds. Quantitative nuclear magnetic resonance spectroscopy (q-NMR) of acetylsalicylic acid (ASA) was conducted using tert-butyl alcohol (tert-butanol) as the internal standard and deuterated chloroform (CDCl3) as the solvent. Preparations of ASA solutions in low and high concentration ranges, 1.0 mM – 10.1 mM ...
The Investigation Of The Electrical Control Of Hemimicelles And Admicelles On Gold For Analyte Preconcentration, 2016 Western Kentucky University
The Investigation Of The Electrical Control Of Hemimicelles And Admicelles On Gold For Analyte Preconcentration, Dheyaa Hussein Al-Karawi
Masters Theses & Specialist Projects
Hemimicelles and admicelles are well-investigated wonders in modern science; they are surfactant monolayers and surface adsorbed micelles, respectively. Capacitance measurements for monitoring the formation of dodecyl sulfate (DS) surfactant monolayer on positively charged gold substrates (planar gold) and the adsorbance of 2-naphthol onto DS surfactant monolayer were performed. The investigation of the electrical control of DS at various concentrations (4, 6, 16, and 32 mM) below and above the critical micelle concentration (CMC= 8 mM) on gold surfaces for analyte preconcentration, prior to chromatographic analysis, is presented. Charged ionic surfactants, such as DS, drawn to a surface of opposite charge ...
Electrochemical Nanoprobes For Electron Transfer Kinetics And Electrocatalysis Study, 2016 The Graduate Center, City University of New York
Electrochemical Nanoprobes For Electron Transfer Kinetics And Electrocatalysis Study, Yun Yu
All Graduate Works by Year: Dissertations, Theses, and Capstone Projects
The studies of electrochemical processes on the nanoscale have led to a significant progress in understanding of electrochemical mechanisms and characterization of nanomaterials in the fields of energy, catalysis, and biological research. Electrochemical experiments at nanoscale require the fabrication and characterization of nanometer-sized electrochemical probes. The main advantages of the nanoprobes include very fast mass-transfer rate, high signal-to-noise ratio and extremely fine spatial resolution of electrochemical imaging. In the course of my Ph.D. research, different types of electrochemical probes were developed for measuring electron-transfer kinetics, probing single catalytic nanoparticles and sampling ultra-small volume of liquids.
We developed methodologies to ...
Investigating Mycotoxins And Secondary Metabolites In Canadian Agricultural Commodities Using High-Resolution Mass Spectrometry, 2016 The University of Western Ontario
Investigating Mycotoxins And Secondary Metabolites In Canadian Agricultural Commodities Using High-Resolution Mass Spectrometry, Megan J. Kelman
Electronic Thesis and Dissertation Repository
Mycotoxins are secondary metabolites produced by fungi, which are harmful to humans and/or animals. Alternaria is a common fungal plant pathogen that can produce mycotoxins in agricultural commodities, such as processed wheat products, and fruit juices. Liquid chromatography mass spectrometry (LC-MS) is commonly used for the detection, characterization and quantitation of mycotoxins in agricultural products. Canadian Alternaria species were assessed to provide a risk assessment of their secondary metabolites in agricultural products by describing their global metabolome data obtained from the Orbitrap LC-MS instrument. Combination of this high mass accuracy data with post data-acquisition analysis techniques resulted in the ...
Fabricating And Characterizing Chalcogenide Thin Films As Light Absorbing Layers In Solar Cells, 2016 The University of Western Ontario
Fabricating And Characterizing Chalcogenide Thin Films As Light Absorbing Layers In Solar Cells, Daniel Vaccarello
Electronic Thesis and Dissertation Repository
Solar cell development has been a focus in energy research, with light-absorbing layers as the key theme. Copper indium disulphide (CuInS2) and copper zinc tin sulphide (Cu2ZnSnS4 or CZTS) have energy band gaps that are optimal for solar energy conversion. New preparation methods have been developed with practicality, safety, and low costs in mind. The one-pot method developed in this thesis group has been utilized to create nanocrystals that can be used to absorb light and generate current. The use of low temperatures and minimalistic reaction conditions has led to the production of CIS and CZTS ...
First Line Shape Analysis And Spectroscopic Parameters For The Ν11 Band Of 12c2h4, 2016 Paul Scherrer Institute (PSI)
First Line Shape Analysis And Spectroscopic Parameters For The Ν11 Band Of 12c2h4, Et-Touhami Es-Sebbar, John Johnmantzaras, Yves Benilan, Aamir Farooq
Dr. Et-touhami Es-sebbar
Comparative Analysis Of In Situ Fibronectin Using Tof-Sims, Spi-Ms, And Dropdesi-Ms In A Microfluidic Reactor, 2016 Pacific Northwest National Laboratory
Comparative Analysis Of In Situ Fibronectin Using Tof-Sims, Spi-Ms, And Dropdesi-Ms In A Microfluidic Reactor, Shannon Fasing, Xiao-Ying Yu, Juan Yao, Jiachao Yu
STAR (STEM Teacher and Researcher) Presentations
Fibronectin is an important biomolecule due to its role in cell differentiation, growth, kinesis, and adhesion. Such biological responses are mediated through membrane recognition and signaling; where fibronectin is found. Studying the outer molecular surface of fibronectin allows deeper insight into the microbiological reactions that occur during these processes. In situ mass spectrometry analysis in aqueous solution accurately represents fibronectin’s chemical components, made possible by a vacuum compatible microfluidic reactor, SALVI (System for Analysis at the Liquid Vacuum Interface). SALVI was paired with the analytical tools: time-of-flight secondary ion mass spectrometer (ToF-SIMS), single photon ionization mass spectrometer (SPI-MS) and ...