Tumor-Targeting Fluorinated Phthalocyanines For Theranostic Applications, 2018 Seton Hall University
Tumor-Targeting Fluorinated Phthalocyanines For Theranostic Applications, Erik Nathaniel Carrión
Seton Hall University Dissertations and Theses (ETDs)
Hydrocarbon-based therapeutics and imaging agents are prone to chemical oxidation and degradation resulting in loss of activity and limited functional utility. Thus, more material is required to achieve long-lasting therapeutic effects. Phthalocyanines (Pcs) and their metal complexes (PcMs) can be utilized as prodrugs requiring only renewable energy resources namely, air and light, for cancer therapy and diagnostic (theranostic) applications related to photodynamic therapy (PDT). Replacement of labile C-H bonds in the Pc scaffold with a combination of fluoro and perfluoroisopropyl groups has resulted in a stable yet reactive oxidation catalyst of biological significance and importance. For example, F64PcZn ...
Polymer Nanocomposites Containing High Aspect Ratio Particulates: Innovation In Co-Extruded Multilayer Barrier Films, 2018 The University of Southern Mississippi
Polymer Nanocomposites Containing High Aspect Ratio Particulates: Innovation In Co-Extruded Multilayer Barrier Films, Kevin Meyers
Delaminated montmorillonite (MMT) clay/ maleic anhydride grafted LLDPE nanocomposite multilayer films with alternating layers of LDPE were produced through multilayer co-extrusion. The MMT concentration within the nanocomposite layers was increased through annealing the films in the melt due to a mismatch in interdiffusion rates of the polymer layers. Analysis of the nanocomposite layers upon annealing revealed that the platelets impinged upon one another resulting in significant improvement in oxygen barrier in the multilayer system, exceeding the results of bulk nanocomposites.
Model analysis demonstrated that increasing the nanoplatelet aspect ratio or initial concentration in the filled layers would lead to even ...
Lithium And The Foreseeable Future, 2018 University of Arkansas, Fayetteville
Lithium And The Foreseeable Future, Paolo Vargas
Mechanical Engineering Undergraduate Honors Theses
This paper aims to clarify the uncertainties regarding worldwide lithium resource availability in the years to come. Previous studies made on the subject are presented with some ambiguity and this work intends to fill the gaps. The information and data presented throughout this script with respect to global lithium resources and reserves are mostly based on data released by the United States Geological Survey (USGS). Lithium resource availability in the future is a point of paramount significance primarily for the automotive, portable electronics, and the power generation industry. Since, a change of supply would ultimately affect the price of lithium ...
Evaluation Of The Biocompatibility And Micromechanical Properties Of Experimental Dental Adhesives, 2018 State University of New York College at Buffalo - Buffalo State College
Evaluation Of The Biocompatibility And Micromechanical Properties Of Experimental Dental Adhesives, Hoda Moussa
Forensic Science Theses
The purpose of this study was to investigate the biocompatibility and micromechanical properties of newly synthesized antibacterial monomer and cross-linker functional surfactants into a commercially available dental adhesive (Single Bond, 3M ESPE, Saint Paul, MN, USA) at three concentrations (0.05, 0.1, 0.25 mg/mg). All groups were analyzed by evaluation of micro-tensile bond strength, ultimate tensile strength, cell viability, antibacterial properties, and surface micro-hardness. Scanning electron microscopy (SEM) was used for interfacial characterization.
Human extracted molars were used as a substrate for bonding adhesives for the micro-tensile bond strength (MTBS) and scanning electron microscopy (SEM) studies. Twenty ...
Workflows For X-Ray And Neutron Interferometry/Tomography As Applied To Additive Manufacturing, 2018 Louisiana State University and Agricultural and Mechanical College
Workflows For X-Ray And Neutron Interferometry/Tomography As Applied To Additive Manufacturing, Jumao Yuan
LSU Doctoral Dissertations
Grating-based interferometry/tomography is being rapidly developed for non-destructive evaluation of additive manufacturing test articles. An application requiring an eﬃcient workﬂow is extremely necessary for stress and fatigue testing samples.
At present, scientiﬁc workﬂows play an important role for computational experiments in additive manufacturing 3D printing and interferometry/tomography imaging analysis. A clear workﬂow template allows scientists to process experiments easier and faster. Work ﬂow library grows, but to ﬁnd an appropriate workﬂow for their task is challenging. In our research, there are mainly three portions in the workﬂow, interferometry analysis, image reconstruction and 3D visualization. Currently, the hierarchy of ...
Use Of Bioadvantaged Materials For Use In Bituminous Modification, 2018 Iowa State University
Use Of Bioadvantaged Materials For Use In Bituminous Modification, Conglin Chen, Joseph H. Podolsky, Nacú B. Hernández, Austin Hohmann, R. Christopher Williams, Eric W. Cochran
Eric W. Cochran
Historically, the use of “green” materials around the world has been limited due to their higher production costs when compared to petrochemical derived materials. However, due to the recent volatility and increasing price of petroleum derivatives, there is a growing demand for the use of environmentally friendly materials. One of the most commonly used materials for bitumen modification are poly(styrene-block-butadiene-block-styrene) (SBS) type polymers. Recently, Iowa State University Chemical Engineering Department was able to synthetize thermoplastic elastomers using acrylated epoxidized soybean oil (AESO), a bioadvantaged replacement of butadiene, and styrene with the use of controlled radical polymerization techniques. Initial rheological ...
Synthesis And Functionalization Of Virus-Mimicking Cationic Block Copolymers With Pathogen-Associated Carbohydrates As Potential Vaccine Adjuvants, J. R. Adams, M. Goswami, N. L.B. Pohl, Surya K. Mallapragada
Surya K. Mallapragada
We report the synthesis of a family of amphiphilic pentablock polymers with different cationic blocks and with controlled architectures as potential vaccine carriers for subunit vaccines. The temperature and pH-dependent micellization and gelation of these pentablock copolymers can provide a depot for sustained protein and gene delivery. The amphiphilic central triblock promotes cellular endocytosis, good gene delivery and has been used effectively as a vaccine adjuvant. The pentablock copolymer outer blocks condense DNA spontaneously as a result of electrostatic interactions for sustained combinational therapy. This family of polymers with different cationic groups was evaluated based on DNA complexation-ability and cytotoxicity ...
Abnormal Phase Transition Between Two-Dimensional High-Density Liquid Crystal And Low-Density Crystalline Solid Phases, 2018 University of Chinese Academy of Sciences
Abnormal Phase Transition Between Two-Dimensional High-Density Liquid Crystal And Low-Density Crystalline Solid Phases, Wenbin Li, Longjuan Kong, Baojie Feng, Huixia Fu, Hui Li, Xiao Cheng Zeng, Kehui Wu, Lan Chen
Xiao Cheng Zeng Publications
Some two-dimensional liquid systems are theoretically predicted to have an anomalous phase transition due to unique intermolecular interactions, for example the first-order transition between two-dimensional high-density water and low-density amorphous ice. However, it has never been experimentally observed, to the best of our knowledge. Here we report an entropy-driven phase transition between a high-density liquid crystal and low-density crystalline solid, directly observed by scanning tunneling microscope in carbon monoxide adsorbed on Cu(111). Combined with first principle calculations, we find that repulsive dipole–dipole interactions between carbon monoxide molecules lead to unconventional thermodynamics. This finding of unconventional thermodynamics in two-dimensional ...
Modification Of Wheat Gluten For Improvement Of Binding Capacity With Keratin In Hair, 2018 Jiangnan University
Modification Of Wheat Gluten For Improvement Of Binding Capacity With Keratin In Hair, Shukun Wang, Danyang Meng, Sisi Wang, Zhong Zhang, Ruijin Yang, Wei Zhao
Faculty Publications in Food Science and Technology
In this study, enzymatic hydrolysis and cationization with epoxypropyldodecyldimethylammonium chloride of wheat protein, an economic protein complex containing great amount of disulfide bonds, were conducted to improve properties such as solubility and disassociation behaviour for recovery of damaged hair when used in shampoo. The optimal conditions for enzymatic hydrolysis were pH 8.2, 55°C with Alcalase for 60min. After the selected hydrolysis, the degree of hydrolysis, nitrogen solubility index, foaming capacity index, foam stability index, emulsifying activity index and emulsion stability index of hydrolysate with 58.71% of shortchain peptides (less than 1000 Da) were 8.81%, 39.07 ...
Carbon Quantum Dots: Bridging The Gap Between Chemical Structure And Material Properties, 2018 University of Kentucky
Carbon Quantum Dots: Bridging The Gap Between Chemical Structure And Material Properties, Timothy J. Pillar-Little Jr.
Theses and Dissertations--Chemistry
Carbon quantum dots (CQDs) are the latest generation of carbon nanomaterials in applications where fullerenes, carbon nanotubes, and graphene are abundantly used. With several attractive properties such as tunable optical property, edge-functionalization, and defect-rich chemical structure, CQDs have the potential to revolutionize optoelectronics, electro- and photocatalysis, and biomedical applications. Chemical modifications through the addition of heteroatoms, chemical reduction, and surface passivation are found to alter the band gap, spectral position, and emission pathways of CQDs. Despite extensive studies, fundamental understanding of structure-property relationship remains unclear due to the inhomogeneity in chemical structure and a complex emission mechanism for CQDs.
Light-Harvesting And Light-Responsive Materials For Optoelectronic And Biological Applications, 2018 University of Massachusetts Amherst
Light-Harvesting And Light-Responsive Materials For Optoelectronic And Biological Applications, Youngju Bae
In photodynamic therapy, several critical standards are required of photosensitizers including high singlet oxygen quantum yield, biocompatibility in dark, and long term photochemical stability. In addition, current PDT systems lack active targeting strategies to tumor cells, and instead mainly rely on the natural distribution of PS in the body following injection and application of near-infrared light treatment in the tumor region. This thesis describes a series of BODIPY-based molecules that were designed, synthesized and studied as photosensitizers with high singlet oxygen generation capacity through utilizing the heavy atom effect. Additionally, aqueous solubility and active targeting capability were introduced by photosensitizer ...
Interfacial Corrosion Of Copper And The Formation Of Copper Hydroxychloride, 2018 The University of Akron
Interfacial Corrosion Of Copper And The Formation Of Copper Hydroxychloride, Mary Teague, Shengxi Li, Hongbo Cong
Honors Research Projects
Electrical circuitry is an industry, among many others, heavily using the element of copper. Ensuring the mechanical integrity of Cu is crucial, especially in salt environments, for the multifaceted composition of circuits. 4N NaCl solution (equilibrium concentration in ~84% RH) simulated this three-phase system. Rectangular Cu samples were partially immersed in both ambient and continuous lab air sparging atmospheres to understand waterline corrosion of the metal. Open circuit potentials (OCP) were continuously taken during the immersion testing for a maximum of 5 days. A scanning electron microscopy (SEM) equipped with an energy dispersive X-ray spectrometer (EDS), Raman spectroscopy, and 3-D ...
Recycled Sm-Co Bonded Magnet Filaments For 3d Printing Of Magnets, 2018 Ames Laboratory
Recycled Sm-Co Bonded Magnet Filaments For 3d Printing Of Magnets, Helena A. Khazdozian, J. Sebastian Manzano, Kinjal Gandha, Igor I. Slowing, Ikenna C. Nlebedim
Ames Laboratory Accepted Manuscripts
Recycling of rare earth elements, such as Sm and Nd, is one technique towards mitigating long-term supply and cost concerns for materials and devices that depend on these elements. In this work recycled Sm-Co powder recovered from industrial grinding swarfs, or waste material from magnet processing, was investigated for use in preparation of filament for 3D printing of bonded magnets. Recycled Sm-Co powder recovered from swarfs was blended into polylactic acid (PLA). Up to 20 vol.% of the recycled Sm-Co in PLA was extruded at 160°C to produce a filament. It was demonstrated that no degradation of magnetic properties ...
Physicochemical, Spectroscopic Properties, And Diffusion Mechanisms Of Small Hydrocarbon Molecules In Mof-74-Mg/Zn: A Quantum Chemical Investigation, 2018 Michigan Technological University
Physicochemical, Spectroscopic Properties, And Diffusion Mechanisms Of Small Hydrocarbon Molecules In Mof-74-Mg/Zn: A Quantum Chemical Investigation, Gemechis Degaga
Dissertations, Master's Theses and Master's Reports
In petroleum refining industries, the fracturing process allows for the cracking of long-chain hydrocarbons into a mixture of small olefin and paraffin molecules that are then separated via the energetically and monetarily demanding cryogenic distillation process. In an attempt to mitigate both energetic and capital consumptions, selective sorption of light hydrocarbons by tunable sorbents, such as metal-organic frameworks (MOFs), appears to be the most promising alternative for a more efficient gas separation process. MOFs are novel porous materials assembled from inorganic bricks connected by organic linkers. From a crystal engineering stand point, MOFs are advantageous in creating a range of ...
Characterization Of Tetraethyl Orthosilicate-Based Dynamic Hydrogels For Use As Reversible 3-D Cell Culture Matrices, 2018 University of Montana, Missoula
Characterization Of Tetraethyl Orthosilicate-Based Dynamic Hydrogels For Use As Reversible 3-D Cell Culture Matrices, Krisitan Stipe
Graduate Student Theses, Dissertations, & Professional Papers
No abstract provided.
Adsorbed Gas Behaviour And Guest-Host Interactions In Ultramicroporous Metal-Organic Frameworks, 2017 The University of Western Ontario
Adsorbed Gas Behaviour And Guest-Host Interactions In Ultramicroporous Metal-Organic Frameworks, Bligh Desveaux
Electronic Thesis and Dissertation Repository
Metal-organic frameworks (MOFs) are a class of porous materials that have attracted much attention due to their large surface areas, high tunability and their high selectivity for gas adsorption applications. In this work, solid-state nuclear magnetic resonance (SSNMR) experiments and single crystal X-ray diffraction (SCXRD) experiments are used to investigate carbon dioxide adsorption within the ultramicroporous MOFs SIFSIX-3-Zn (Chapter 2) and ZnAtzOx. (Chapter 3). Analysis finds that the CO2 SIFSIX-3-Zn undergoes wobbling motions with a low temperature dependence, and in ZnAtzOx undergoes wobbling and hopping motions with a low temperature dependence. SCXRD is used to precisely determine the CO ...
Synthesis And Characterization Of Thermoresponsive Hydrogels Based On N-Isopropylacrylamide Crosslinked With 4,4′-Dihydroxybiphenyl Diacrylate, Shuo Tang, Martha Floy, Rohit Bhandari, Manjula Sunkara, Andrew J. Morris, Thomas D. Dziubla, J. Zach Hilt
Chemical and Materials Engineering Faculty Publications
A novel crosslinker [4,4′-dihydroxybiphenyl diacrylate (44BDA)] was developed, and a series of temperature-responsive hydrogels were synthesized through free radical polymerization of N-isopropylacrylamide (NIPAAm) with 44BDA. The temperature-responsive behavior of the resulting gels was characterized by swelling studies, and the lower critical solution temperature (LCST) of the hydrogels was characterized through differential scanning calorimetry. Increased content of 44BDA led to a decreased swelling ratio and shifted the LCST to lower temperatures. These novel hydrogels also displayed resiliency through multiple swelling–deswelling cycles, and their temperature responsiveness was reversible. The successful synthesis of NIPAAm-based hydrogels crosslinked with 44BDA has ...
Artificial Olfactory System For Multi-Component Analysis Of Gas Mixtures., 2017 University of Louisville
Artificial Olfactory System For Multi-Component Analysis Of Gas Mixtures., Alexander Aleksandrovich Larin
Electronic Theses and Dissertations
Gas analysis is an important part of our world and gas sensing technology is becoming more essential for various aspects of our life. A novel approach for gas mixture analysis by using portable gas chromatography in combination with an array of highly integrated and selective metal oxide (MOX) sensors has been studied. We developed a system with small size (7 x 13 x 16 inches), low power consumption (~10 W) and absence of special carrier gases designed for portable field analysis (assuming apriori calibration). Low ppb and even sub-ppb level of detection for some VOCs was achieved during the analysis ...
Analysis Of Primary Stripper Foils At The Spallation Neutron Source By An Electron Beam Foil Test Stand, 2017 University of Tennessee, Knoxville
Analysis Of Primary Stripper Foils At The Spallation Neutron Source By An Electron Beam Foil Test Stand, Eric Paul Barrowclough
Diamond films are used at the Spallation Neutron Source (SNS) as the primary charge exchange foils (i.e., stripper foils) of the accelerated 1 GeV (Gigaelectron volts) hydride ions. The most common type of film used is a nanocrystalline diamond film, typically 17 mm x 45 mm (millimeter) with an aerial density of 350 μg/cm2 (microgram per square centimeter). The diamond film is deposited on a corrugated silicon substrate using plasma-assisted chemical vapor deposition. After the growth of the diamond film, 30 mm of the silicon substrate is etched away, leaving a freestanding diamond foil with a silicon ...
Investigating Scalable Manufacturing Of High-Conductivity Wires And Coatings From Ultra-Long Carbon Nanotubes, 2017 University of New Mexico - Main Campus
Investigating Scalable Manufacturing Of High-Conductivity Wires And Coatings From Ultra-Long Carbon Nanotubes, Pouria Khanbolouki
Mechanical Engineering ETDs
Carbon nanotubes (CNTs) are a promising candidate for next generation of electrical wirings and electromagnetic interference (EMI) shielding materials due to their exceptional mechanical and electrical properties. Wires and coatings from ultralong nanotubes that are highly crystalline, well-aligned and densely packed can achieve this goal. High-performance CNT conductors will be relatively lightweight and resistant to harsh conditions and therefore can potentially replace current conductors in many industries including aerospace, automotive, gas and oil.
This thesis investigates a new manufacturing approach, based on conventional solution coating and wire drawing methods, to fabricate high conductivity wires and coatings from ultra-long carbon nanotubes ...