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Environmental Enrichment Attenuates Nucleus Basalis Lesion Induced Impairments To Attention, Brandee Leianne Kinney-Hurd 2010 California State University, San Bernardino

Environmental Enrichment Attenuates Nucleus Basalis Lesion Induced Impairments To Attention, Brandee Leianne Kinney-Hurd

Theses Digitization Project

This experiment examined the effects of environmental enrichment on performance in an attention-dependent learning task in rats with selective lesions of the cholinergic nucleus basalis magnocellularis (NBM). The findings demonstrate that environmental enrichment can enhance attention-dependent learning performance in normal animals as well as attenuating NBM lesion-induced impairments otherwise seen following rearing in standard conditions.


Effects Of Chronic Paroxetine And Fluoxetine Treatment On Markers Of Suicidal Behavior In Adolescent Rats, Leslie Renee Horn 2010 California State University, San Bernardino

Effects Of Chronic Paroxetine And Fluoxetine Treatment On Markers Of Suicidal Behavior In Adolescent Rats, Leslie Renee Horn

Theses Digitization Project

Major depression is a common problem in adolescents. Unfortunately, one of the most effective antidepressants in adults, the selective serotonin reuptake inhibitor (SSRI) paroxetine, is not clinically effective in pediatric populations. There are many variables that increase the risk of suicide including genetic, social, psychological, and biological factors, making the evaluation of the effect of SSRIs on suicidal behavior difficult to assess in human adolescents. The goal of the present investigation was to compare the effects of paroxetine and fluoxetine in adolescent rats on markers associated with depression and suicidal behavior in humans.


Consequences Of Early Methylphenidate Exposure On Opioid System Functioning In Adult Rats, Matthew Scott Herbert 2010 California State University, San Bernardino

Consequences Of Early Methylphenidate Exposure On Opioid System Functioning In Adult Rats, Matthew Scott Herbert

Theses Digitization Project

Methylphenidate is the preferred treatment for attention-deficit hyperactivity disorder in preschool-aged children, even though few human studies have assessed the long-term consequences of early methyphenidate use. In rats, exposure to methylphenidate during a developmental period that approximates early childhood increases morphine-induced antinociception in adulthood. However, because morphine activates three distinct opioid receptors it is unknown which receptor is resonsible for this methylphenidate effect. The purpose of the present study was to assess the long-term effects of early methylphenidate exposure on DAMGO- and U50, 488-induced antinociception, a mu-opioid and kappa-opioid selective agonist.


Comparison Of Affective Analgesia And Conditioned Place Preference Following Cholinergic Activation Of, Elena Schifirnet 2010 Wayne State University

Comparison Of Affective Analgesia And Conditioned Place Preference Following Cholinergic Activation Of, Elena Schifirnet

Wayne State University Dissertations

Activation of the dopaminergic mesolimbic reward circuitry that originates in the ventral tegmental area (VTA) is postulated to preferentially suppress affective reactions to noxious stimuli (affective analgesia, AA). VTA dopamine neurons are activated via cholinergic inputs, and we have observed that microinjections of the acetylcholine agonist carbachol suppressed vocalizations of rats that occur following administration of brief (1 sec) tail-shocks (vocalization afterdischarges = VAD). VADs are a validated rodent model of pain affect. In addition, the capacity of carbachol to support reinforcement appears to be regionally dependent within VTA. Ikemoto and Wise (2002) reported that carbachol was self-administered in the …


Effects Of Mindfulness Training On Stress, Mood And Coping In College Students, Lily Preer 2010 Connecticut College

Effects Of Mindfulness Training On Stress, Mood And Coping In College Students, Lily Preer

Psychology Honors Papers

The present study examined the stress-reducing effects of a mindfulness meditation (MM) intervention in college students compared with a progressive muscle relaxation (PMR) exercise and a control group. The participants were 43 Connecticut College students high in interpersonal sensitivity. In the two experimental sessions, participants learned the stress-reduction techniques. Perceived stress, mood, coping and cortisol levels were assessed pre-and post-intervention. Participants completed a follow-up four weeks after the second session. Repeated measures MANOVAS were used to assess changes in stress, mood and coping. There were no changes in perceived stress. Though avoidant coping, cortisol levels, and negative mood decreased in …


Epigenetics: Blurring The Line Between Nature And Nurture, Elizabeth H. Rose 2010 Claremont McKenna College

Epigenetics: Blurring The Line Between Nature And Nurture, Elizabeth H. Rose

CMC Senior Theses

This long-standing nature versus nurture debate is cited in behavioral and physical expressions of disease dysfunctions, resiliencies, and recovery. Their purposes are noted both in scientific pursuits as well as literature. This discourse has been particularly intense in the fields of psychology, psychiatry, and biology where there is a long history of scientists’ attempts to disprove or discredit others’ intellectual and professional measures. Interestingly, recent advances in the neurosciences and genetic technologies have brought these fields closer together with a new focus – the interactional relationship between nature and nurture – epigenetics.


Effects Of Early Developmental Stress On Adult Physiology And Behavior, Michael James Frederick 2010 University at Albany, State University of New York

Effects Of Early Developmental Stress On Adult Physiology And Behavior, Michael James Frederick

Legacy Theses & Dissertations (2009 - 2024)

Events during early development can have long-term effects on physiology and behavior. While extreme developmental stress is known to be associated with a variety of behavioral problems, it is less well understood how milder stress may affect behavior, personality, and reproductive success. This research project assessed a variety of behavioral dimensions in a college age sample, while assessing early development using size at birth, fluctuating asymmetry, and retrospective surveys. Maternal stress during pregnancy was found to reduce adolescent growth spurts and adult handgrip strength in the offspring. In males, lower birth weights were associated with higher scores of impulsivity and …


Biological And Behavioral Correlates Among Young Adults Exposed To Harsh Parenting Practices, Christy Lyn Olezeski 2010 University at Albany, State University of New York

Biological And Behavioral Correlates Among Young Adults Exposed To Harsh Parenting Practices, Christy Lyn Olezeski

Legacy Theses & Dissertations (2009 - 2024)

Whereas the subject of harsh parenting has been a source of debate for many years, research has shown that harsh parenting practices are associated with an increase in behavioral problems, including aggression toward others. However, not all youth who have been subjected to harsh parenting develop problems. Researchers have begun examining moderators of the effects of harsh parenting and other psychosocial stressors, specifically whether functioning in physiological stress response systems buffers or exacerbates the effects of harsh parenting on later functioning. Research also suggests that exposure to stressful situations (including harsh parenting) may affect the biological stress system. In particular, …


The Role Of The Progesterone Receptor In The Development Of The Ventromedial Nucleus And Female Sexual Behaviors, Keith L. Gonzales 2010 University at Albany, State University of New York

The Role Of The Progesterone Receptor In The Development Of The Ventromedial Nucleus And Female Sexual Behaviors, Keith L. Gonzales

Legacy Theses & Dissertations (2009 - 2024)

Steroid induced gene transcription plays an important role in neural sex differences within many mammalian species. Steroid hormones actions within the developing brain have profound, permanent effects in the development of neurochemical processes and behaviors. Within the developing ventromedial nucleus of the hypothalamus (VMN), a potent transcription factor, the progesterone receptor (PR), is highly expressed within female rats. Furthermore, the regulation of PR within the developing VMN of the female rat is anatomically and developmentally specific. Typically, PR expression is highly dependent on the activity of estradiol acting at ERα. As such, circulating levels of estradiol act to induce PR …


The Contribution Of Genes And Hormones To The Sexual Differention Of The Zebra Finch Song System, Jessica Bayley Thompson 2010 Wayne State University

The Contribution Of Genes And Hormones To The Sexual Differention Of The Zebra Finch Song System, Jessica Bayley Thompson

Wayne State University Theses

Recent studies in the zebra finch suggest the sexual differentiation of the song system and singing behavior may not be solely driven by steroid hormones organizing the brain, and may be genetically driven. In fact, genes and hormones might act together to produce sexual differentiation of the brain. To test this hypothesis, animals were implanted with a 1mm pellet containing 50ug of 17b-estradiol or a blank pellet on the third day post-hatching. At post-hatch day 25, the brains were collected and a double label fluorescence in situ hybridization protocol using biotin and digoxigenin-tagged mRNA probes was used to simultaneously label …


Validating Kreiner And Ashforth’S Organizational Identification Measure In An Engineering Context, Morrie Mullins, Christian M. End, L. Carlin 2010 Xavier University - Cincinnati

Validating Kreiner And Ashforth’S Organizational Identification Measure In An Engineering Context, Morrie Mullins, Christian M. End, L. Carlin

Faculty Scholarship

No abstract provided.


Integrity Of Neuropsychological Processes In Children With Attention-Deficit/Hyperactivity Disorder And Comorbid Conditions, Julie N. Henzel 2010 Philadelphia College of Osteopathic Medicine

Integrity Of Neuropsychological Processes In Children With Attention-Deficit/Hyperactivity Disorder And Comorbid Conditions, Julie N. Henzel

PCOM Psychology Dissertations

This study investigated the neuropsychological and behavioral profiles seen in children diagnosed with ADHD inattentive type (IA), inattentive type plus an internalizing disorder (IA + INT), combined type (CT), and combined type plus an externalizing disorder (CT + EXT). Subjects were 63 unmedicated children aged 6 to 16 who had been assessed with the Wechsler Intelligence Scale for Children–Fourth Edition (WISC–IV), Conners’ Continuous Performance Test-Second Edition (CPT–II), and the Child Behavior Checklist (CBCL). Group differences were found for the WISC–IV Digits Backward subtest (IA + INT IA and IA + INT), and externalizing behavior scales on the CBCL and TRF …


Using A Structured Decision Making Protocol To Stratify Caseloads In The Child Support Program, Steven J. Golightly 2010 Walden University

Using A Structured Decision Making Protocol To Stratify Caseloads In The Child Support Program, Steven J. Golightly

Walden Dissertations and Doctoral Studies

Although structured decision making and risk assessment protocols have successfully been used in human service programs, little research has been done on their applicability in the child support program. In this study, problems identified with child support case management were examined, along with positive and negative attributes of various risk assessment tools utilized in other arenas. The overall research problem asserted that there are no structured decision making protocols in the child support program to support case assignment by enforcement difficulty. The primary research question asked whether or not a process stratified by risk and level of enforcement difficulty could …


Functionality, Parsimony, Discovery, Avoiding Hamartia: How Evolutionary Perspectives Are Changing Psychology, Brooke N. Jenkins, Aaron T. Goetz 2010 Chapman University

Functionality, Parsimony, Discovery, Avoiding Hamartia: How Evolutionary Perspectives Are Changing Psychology, Brooke N. Jenkins, Aaron T. Goetz

Psychology Faculty Articles and Research

Evolutionary psychology offers an important perspective to scientific psychology. Evolutionary psychology, in its short existence, has added an abundance of knowledge to the social sciences, let alone psychology. The study of human cognition and behavior remains incomplete without an evolutionary perspective. Here, we argue that evolutionary psychology uniquely provides a complete understanding of scientific psychology because it explains the functions of our psychological traits, provides us with the most parsimonious explanation of many psychological phenomena, predicts undocumented phenomena, and possibly allows us to avoid the downfalls of some of our contemptible evolved psychological mechanisms.


A Phenomenological Inquiry Of Chronic Homeless Individuals' Challenges To Independence, Dewana Hall 2010 Walden University

A Phenomenological Inquiry Of Chronic Homeless Individuals' Challenges To Independence, Dewana Hall

Walden Dissertations and Doctoral Studies

Homelessness is a comprehensive social problem affecting approximately 744,000 people in the U.S. Despite consistent efforts from politicians, state and local leaders, and service providers, the number of homeless people continues to rise. Although there are some explanations in the literature to account for the increase of homelessness, the literature tends to not include the voices of the homeless themselves. The purpose of this phenomenological study, which used Maslow's hierarchy of needs as its conceptual framework, was to understand the life experiences of members of the homeless population, as perceived by four male residents of a mission in an eastern …


Illness Uncertainty, Ways Of Coping, And Psychological Adjustment Among 18--25-Year-Olds With Anaphylactic Food Allergy, Susan J. Cohen 2010 Walden University

Illness Uncertainty, Ways Of Coping, And Psychological Adjustment Among 18--25-Year-Olds With Anaphylactic Food Allergy, Susan J. Cohen

Walden Dissertations and Doctoral Studies

The prevalence of food allergy is increasing, with adolescents and young adults being the group most likely to die from food-induced anaphylaxis. Behavioral and psychological factors contribute to this risk. This study investigated the relationship between illness uncertainty (as measured by the Mishel Uncertainty in Illness Scale Community Form) and emotion- and problem-focused coping (as measured by the Ways of Coping Scale), to see if they contributed to psychological adjustment (as measured by the Depression Anxiety Stress Scale-21) in this population. A cognitive diathesis-stress model was used to explain individual differences in adjustment. Multiple regression was used to test illness …


Administration Of A Cannabinoid Receptor Antagonist Following Chronic ∆9-Tetrahydrocannabinol Induces Physical Withdrawal In The Absence Of A Dysphoric State, Brittany Ford 2010 Wilfrid Laurier University

Administration Of A Cannabinoid Receptor Antagonist Following Chronic ∆9-Tetrahydrocannabinol Induces Physical Withdrawal In The Absence Of A Dysphoric State, Brittany Ford

Theses and Dissertations (Comprehensive)

The selective cannabinoid CB1 receptor antagonist SR141716 has been shown to precipitate physical signs of withdrawal in ∆9-tetrahydrocannabinol (THC)-dependent rats; however, the affective state associated with this withdrawal state has not yet been well characterized. Thus, the aim of present study was to examine the physical and affective consequences of SR141716-precipitated THC withdrawal in male Sprague-Dawley rats. Rats were injected with THC (5 mg/kg, i.p.) or its vehicle twice daily for 13 consecutive days, and challenged with SRI 41716 (1 mg/kg, i.p.) or its vehicle 1 h later on days 3, 5, 7, 9, 11, and 13. Consistent …


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