Biological Psychology Commons^™

Repeated Binge Pattern Ethanol Administration During Adolescence Or Adulthood: Long-Term Changes In Voluntary Ethanol Intake And Mesolimbic Dopamine Functionality In Male Rats, Antoniette Michelle Maldonado-Devincci

USF Tampa Graduate Theses and Dissertations

Binge alcohol consumption is a rising concern in the United States, especially among adolescents as during this developmental period alcohol use is usually initiated and has been shown to cause detrimental effects on brain structure and function. These findings have been established through the use of binge models in animals, where animals are repeatedly administered high doses of ethanol typically over a period of three or four days. While such work has examined the effects of a four-day and repeated three-day binge, there has been almost no work conducted aimed at investigating the long-term behavioral and neurochemical and/or functional consequences …

Effect Of Stress, Emotional Lability And Depression On The Development Of Pregnancy Complications, Servitje, Estibalitz Laresgoiti Servitje

Walden Dissertations and Doctoral Studies

Chronic stress and other emotional factors may have relevant impacts on pregnancy outcomes because they are related to neuroendocrine changes that lead to alterations in immunomodulation during pregnancy. In this quantitative prospective cross-sectional study, the relationship of emotional lability, depression, and stress during pregnancy and the development of preterm labor, preeclampsia, placental abruption, and low birth weight for gestational age babies was examined. Additionally, social support scores were compared to levels of stress/anxiety, depression, and emotional lability in pregnant women. Two hundred and forty two pregnant women who received prenatal services at the National Institute of Perinatology in Mexico City …

Do We Know What We Know? Self- Assessment Across The Lifespan, Courtney Clare Lee

Master's Theses

Self-knowledge can play a critical role in navigating physical, cognitive, and social changes in late life. To protect and preserve one's sense of self against these changes, individuals may engage in self-enhancing and self-serving biases in areas important to self-esteem. The importance attached to these areas may change with age, and self-knowledge of these psychological processes may vary with age. We investigated self-enhancing biases and metacognitive awareness of abilities in adulthood. Participants ranging in age from 20 to 80 completed a series of tests assessing the better than average effect across a variety of age-relevant domains as well as objective …

Examining The Inner Experience Of Left-Handers Using Descriptive Experience Sampling, Aadee Mizrachi

UNLV Theses, Dissertations, Professional Papers, and Capstones

Research suggests that there are anatomical asymmetries of the human brain in relation to hand preference. In addition, left-handedness has been related to a wide range of psychological and physical problems. Despite these relationships, little is known about the inner experience of left-handers. The present study used Descriptive Experience Sampling (DES) to explore the inner experience of 6 left-handed participants. Descriptive Experience Sampling is a nonquantitative sampling method designed to explore and describe inner experience. Undergraduate psychology students were recruited from UNLV to participate in the study. Recruitment consisted of three phases: screening, qualification, and sampling. Students who reported writing …

Neuropsychological And Emotion Processing Abnormalities In Bipolar Disorder I And Ii, Carol Randall

UNLV Theses, Dissertations, Professional Papers, and Capstones

Bipolar disorder illness is marked by emotional lability and mood disturbance, as well as various neuropsychological deficits, and the neuroanatomical correlates of many of these deficits are beginning to be identified. Numerous studies have implicated specific cortical and sub-cortical abnormalities in areas associated with executive function, memory, motor function, and the processing of emotion. Although a large body of research has been devoted to the investigation of cognitive and emotion-processing deficits in bipolar disorder, relatively few studies have been devoted to the investigation of how these deficits differ among bipolar disorder subtypes. This is surprising in light of known symptomatological …

Information Acquisition And Sociality Among Migratory Birds, Zoltán Németh

Dissertations

Information use is a key feature of adaptive behavior: the better informed an individual, the better it is able to adjust its behavior to meet the demands of a variable world. Therefore, most animals attempt to reduce environmental uncertainty by gathering information when it is available. However, tracking unpredictable ecological factors may carry costs as individuals invest valuable time and energy in the process of information acquisition. Social learning (i.e., use of social information inadvertently produced by other individuals) enables the individual to gain rapid and more complete assessment of its novel environment. This process may be particularly important for …

Taking Charge Of Adult Adhd, P. S. Mcmillen

Library Faculty Research

Barkley is one of the leading researchers and most prolific writers on attention deficit/hyperactivity disorder (ADHD) across the life span, having produced materials for mental health professionals and self-help books like this volume.

Effect Of Depression On Attention Via Mood Induction In A Healthy Population, Cheryl Mae Calvano

Loma Linda University Electronic Theses, Dissertations & Projects

This project continues research into the cognitive attention of persons with a sad mood similar to that experienced by dysthymia. The project utilizes the Dot Probe Task to evaluate attention to affective stimuli presented in the International Affective Picture Set (IAPS). Participants were psychology students recruited from La Sierra University. Participants completed a word task that intended to induce a sad or neutral mood. The Positive and Negative Affect Scale (PANAS) was used to evaluate the efficacy of the mood induction. Overall, participant’s negative PANAS scale did not differ between groups. Groups differed between administrations of the PANAS on the …

Immune Function And Health Outcomes In Women With Depression, Cherie Howk, Mary P. Bennett

Nursing Faculty Publications

This research reports immune function and health outcomes in women with depression, as compared with a nondepressed control group. Using Psychoneuroimmunolgy theory and a descriptive comparison design, scores on the Beck Depression Inventory (BDI) were used to divide 40 non-hospitalized Caucasian women between the ages of 18 and 65 years into either the control or depression comparison group. Women with depression were found to report significantly more incidences of illness over the previous two months and they were found to have significantly more indicators of illness at the time of the exam as compared to the controls. However, contrary to …

Neural Dedifferentiation In Relation To Risk For Alzheimer's Disease, Nathan C. Hantke

Master's Theses (2009 -)

Functional magnetic resonance imaging (fMRI) research indicates that as an individual's age increases, the task-related spatial extent of neural activation increases. This decrease in neural specificity, or dedifferentiation, is often demonstrated by older adults during challenging cognitive tasks. Cognitively intact individuals at-risk for Alzheimer's disease (AD), as deemed by having an apolipoprotein-E ε4 allele or a family history of AD, demonstrate increased fMRI activation as compared to individuals at lower risk. Using a low effort, high accuracy event-related semantic memory task involving the presentation of famous and non-famous names, we examined spatial neural specificity through a measure of dedifferentiation using …

Cognitive And Psychiatric Predictors To Psychosis In Velocardiofacial Syndrome: A 3-Year Follow-Up Study, Kevin M. Antshel, Robert J. Shprintzen, Wanda Fremont, Anne Marie Higgins, Stephen V. Faraone, Wendy R. Kates

Communication Disorders Faculty Publications

Objective: To predict prodromal psychosis in adolescents with velocardiofacial syndrome (VCFS). Method: 70 youth with VCFS, 27 siblings of youth with VCFS and 25 community controls were followed from childhood (Mean age = 11.8 years) into mid-adolescence (mean age 15.0 years). Psychological tests measuring intelligence, academic achievement, learning/memory, attention and executive functioning as well as measures of parent and clinician ratings of child psychiatric functioning were completed at both time point. Results: Major depressive disorder, oppositional defiant disorder, and generalized anxiety disorder diagnoses increased in the VCFS sample. With very low false positive rates, the best predictor of adolescent prodromal …

Neuropsychological Functioning And Attrition Rates In Outpatient Substance Dependence Treatment, Sandra M. Adams

Dissertations (1934 -)

Numerous neuropsychological factors have been associated with substance dependence, however, very few studies have evaluated the relationship of the neuropsychological functioning and attrition rates in substance dependence treatment. This study examined the relationship of neuropsychological functioning and attrition rates in 68 homeless, substance dependent men participating in outpatient treatment at the 7C's Community Counseling Clinic located in the Guesthouse of Milwaukee, Wisconsin. A neuropsychological battery including the Delis Kaplan Executive Functioning System, the Conners' Continuous Performance Test II, the Wechsler Abbreviated Scale of Intelligence (WASI) and the Wechsler Test of Adult Reading was given to all participants to evaluate neuropsychological …

Effects Of Chlordiazepoxide On Predator Odor-Induced Reductions Of Playfulness In Juvenile Rats, Stephen M. Siviy, Courtney L. Steets, Lauren M. Debrouse

Psychology Faculty Publications

The extent to which a non-sedative dose of chlordiazepoxide (CDP) is able to modify the behavioral responses toward a predator odor was assessed in juvenile rats. Play behavior was suppressed and defensive behaviors were enhanced in the presence of a collar previously worn by a cat, when tested 24 hours later in the same context as that where the exposure occurred, and when tested in a context different than that in which the exposure occurred for up to 3 hours after exposure. CDP had no effect on the ability of cat odor to suppress play when rats were tested in …

Effects Of Cb2 Receptor Activation On Variable Chronic Mild Stress (Cms) Induced Depression And Hippocampal Dependant Spatial Learning, Eli Shobin

Psychology Honors Papers

Major Depressive Disorder (MDD) accounts for approximately 10% of all diagnosed chronic illness in the United States. The most common treatments for MDD is serotonergic manipulation via pharmacological treatments such as monoamine oxidase inhibitors (MAO-I) or selective serotonin reuptake inhibitors (SSRI). However, not only have these treatments proven to be ineffective for a portion of the population, but they also fail to treat some of the physiological damages that occur in the hippocampus during MDD due to over-activation of inflammatory cells known as microglia. Activation of the CB2 receptor in the hippocampus has been shown to inhibit microglial cells and …

Environmental Enrichment Attenuates Nucleus Basalis Lesion Induced Impairments To Attention, Brandee Leianne Kinney-Hurd

Theses Digitization Project

This experiment examined the effects of environmental enrichment on performance in an attention-dependent learning task in rats with selective lesions of the cholinergic nucleus basalis magnocellularis (NBM). The findings demonstrate that environmental enrichment can enhance attention-dependent learning performance in normal animals as well as attenuating NBM lesion-induced impairments otherwise seen following rearing in standard conditions.

Effects Of Chronic Paroxetine And Fluoxetine Treatment On Markers Of Suicidal Behavior In Adolescent Rats, Leslie Renee Horn

Theses Digitization Project

Major depression is a common problem in adolescents. Unfortunately, one of the most effective antidepressants in adults, the selective serotonin reuptake inhibitor (SSRI) paroxetine, is not clinically effective in pediatric populations. There are many variables that increase the risk of suicide including genetic, social, psychological, and biological factors, making the evaluation of the effect of SSRIs on suicidal behavior difficult to assess in human adolescents. The goal of the present investigation was to compare the effects of paroxetine and fluoxetine in adolescent rats on markers associated with depression and suicidal behavior in humans.

Consequences Of Early Methylphenidate Exposure On Opioid System Functioning In Adult Rats, Matthew Scott Herbert

Theses Digitization Project

Methylphenidate is the preferred treatment for attention-deficit hyperactivity disorder in preschool-aged children, even though few human studies have assessed the long-term consequences of early methyphenidate use. In rats, exposure to methylphenidate during a developmental period that approximates early childhood increases morphine-induced antinociception in adulthood. However, because morphine activates three distinct opioid receptors it is unknown which receptor is resonsible for this methylphenidate effect. The purpose of the present study was to assess the long-term effects of early methylphenidate exposure on DAMGO- and U50, 488-induced antinociception, a mu-opioid and kappa-opioid selective agonist.

Comparison Of Affective Analgesia And Conditioned Place Preference Following Cholinergic Activation Of, Elena Schifirnet

Wayne State University Dissertations

Activation of the dopaminergic mesolimbic reward circuitry that originates in the ventral tegmental area (VTA) is postulated to preferentially suppress affective reactions to noxious stimuli (affective analgesia, AA). VTA dopamine neurons are activated via cholinergic inputs, and we have observed that microinjections of the acetylcholine agonist carbachol suppressed vocalizations of rats that occur following administration of brief (1 sec) tail-shocks (vocalization afterdischarges = VAD). VADs are a validated rodent model of pain affect. In addition, the capacity of carbachol to support reinforcement appears to be regionally dependent within VTA. Ikemoto and Wise (2002) reported that carbachol was self-administered in the …

Effects Of Mindfulness Training On Stress, Mood And Coping In College Students, Lily Preer

Psychology Honors Papers

The present study examined the stress-reducing effects of a mindfulness meditation (MM) intervention in college students compared with a progressive muscle relaxation (PMR) exercise and a control group. The participants were 43 Connecticut College students high in interpersonal sensitivity. In the two experimental sessions, participants learned the stress-reduction techniques. Perceived stress, mood, coping and cortisol levels were assessed pre-and post-intervention. Participants completed a follow-up four weeks after the second session. Repeated measures MANOVAS were used to assess changes in stress, mood and coping. There were no changes in perceived stress. Though avoidant coping, cortisol levels, and negative mood decreased in …

Epigenetics: Blurring The Line Between Nature And Nurture, Elizabeth H. Rose

CMC Senior Theses

This long-standing nature versus nurture debate is cited in behavioral and physical expressions of disease dysfunctions, resiliencies, and recovery. Their purposes are noted both in scientific pursuits as well as literature. This discourse has been particularly intense in the fields of psychology, psychiatry, and biology where there is a long history of scientists’ attempts to disprove or discredit others’ intellectual and professional measures. Interestingly, recent advances in the neurosciences and genetic technologies have brought these fields closer together with a new focus – the interactional relationship between nature and nurture – epigenetics.