Biological Psychology Commons^™

Neuroendocrine And Psychological Factors Associated With Burnout, Compassion Fatigue, And Reduced Compassion Satisfaction In Mental Health Professionals, Michelle Huffman

UNO Student Research and Creative Activity Fair

Mental health professionals are at increased risk for burnout, compassion fatigue, and reduced compassion satisfaction. Burnout is characterized by emotional exhaustion, depersonalization, and loss of personal accomplishment. Compassion fatigue is a more progressed disruption relative to burnout marked by insomnia/nightmares, arousal, loss of objectivity, isolation, and intrusive thoughts. Compassion satisfaction buffers against burnout and compassion fatigue. Although links between demographic, psychological, and biological factors have been documented, interactions between these factors have not been explored. Mental health professionals completed psychological inventories measuring depression, anxiety, burnout, compassion fatigue, and compassion satisfaction. Saliva samples were collected during the Trier Social Stress Test …

Neurotensin Nts1 And Nts2 Receptor Agonists Produce Anxiolytic-Like Effects In The 22-Khz Ultrasonic Vocalization Model In Rats, Floyd F. Steele Iii, Shannon C. Whitehouse, Jacob S. Aday, Adam J. Prus

Journal Articles

Neurotensin is a neuropeptide neurotransmitter that interacts with multiple neurotransmitter systems, including those regulating amygdalar function, via NTS₁ and NTS₂ receptors. Both receptors are expressed in the amygdala and agonists for NTS₁ or NTS₂ receptors have exhibited anxiolytic effects in animal models. Systemic adminstration of NTS₁ receptor agonist PD149163 was recently shown to reduce footshock conditioned 22-kHz ultrasonic vocalizations in rats, suggesting that PD149163 produced an anxiolytic effect. The effects that neurotensin may have or a selective NTS₂receptor agonist may have on 22-kHz vocalizations has yet to be examined. The current study evaluated …

Dopamine D1 And D3 Receptor Polypharmacology In Cocaine Reward And Cocaine Seeking, Ewa J. Galaj

Dissertations, Theses, and Capstone Projects

Background: In the search for efficacious pharmacotherapies to treat cocaine addiction much attention has been given to agents targeting D1 or D3 receptors because of the involvement of these receptors in cocaine-related behaviors. D1 and D3 receptor partial agonists and antagonists have been shown to reduce cocaine reward, reinstatement of cocaine seeking and conditioned place preference (CPP) in rodents and non-human primates. However, translation of these encouraging results with selective D1 or D3 receptor agents has been limited due to a number of factors including toxicity, poor pharmacokinetic properties and extrapyramidal and sedative side effects.

Purpose: Given the …

Capturing The Attention Of Caregivers: Variability In Infant Vocalizations, Catharine A. Castelluccio De Diesbach

Dissertations, Theses, and Capstone Projects

The effect of variability in infant vocalizations on potential caregivers’ heart rate variability (HRV), facial expressions, and subjective ratings on emotional reactions and desire to approach the baby was examined in an evolutionary context. Recordings of non-canonical, canonical, fussing, and crying vocalizations were utilized to elicit physiological and self-reported reactions from sixty participants. Breastfeeding mothers, non-mothers at high estradiol point in menstrual cycle, non-mothers at low estradiol point in menstrual cycle, fathers, and non-fathers were included in the study. Participants wore Polar RS800 heart rate monitors, were video recorded for facial expression analysis, and filled out 11 point self-rating forms …

Sex Differences In The Anxiety Effects Of Cannabinoids, Helen T. French

Dissertations, Theses, and Capstone Projects

Aim: Anxiety disorders are twice as common among women, and those with anxiety disorders are 2-3 times more likely to have a substance abuse disorder than the general populace. However, little data exists on the sexually dimorphic effects of cannabinoids. In male humans and rodents, low acute doses of cannabinoids are anxiolytic while high and/or chronic doses are anxiogenic. In the dose response curve (DRC), we examined whether the biphasic effects of cannabinoids observed in males are also present in females. In the CB1R antagonism study, CP55,940-induced CB1R activation was antagonized via the CB1R-selective antagonist rimonabant to test the hypothesis …

Estradiol, Substance P, And The Pi3k-Akt-Mtor Pathway In The Dorsal Horn Of The Spinal Cord During Inflammatory Pain, Zane Ferguson

Dissertations, Theses, and Capstone Projects

Pain is a critical survival mechanism that signals potential or actual damage, but it can become pathological when it persists beyond the injury. Chronic pain is a major health issue that affects 10-20% of the adult population and is found disproportionately in women. There are numerous, interacting mechanisms underlying this phenomenon. This study used female rats to investigate the impact of estrogens on sensory signaling by substance P, a neuropeptide that contributes to the development of chronic pain, and the PI3K-Akt-mTOR pathway, an intracellular mechanism of nervous system plasticity.

The Potential Of Epigenetics Research To Transform Conceptions Of Phenotype Development, David S. Moore

Pitzer Faculty Publications and Research

Epigenetics remains an exciting subdiscipline of biology, generating discoveries and insights about development. Because epigenetic phenomena can draw attention to the dynamic, interactional, and probabilistic nature of phenotype development, epigenetics research could hasten the demise of both nature-nurture debates and reductionist, genetically determinist perspectives on phenotype development. However, new data alone will not inevitably transform conceptualizations of phenotype origins, because it remains possible to assimilate epigenetic phenomena into traditional conceptual frameworks; epigenetic discoveries could even strengthen biologically determinist conclusions if traditional conceptualizations are retained. Although epigenetics will not force conceptual transformation, epigenetics research encourages the dismissal of the nature-nurture dichotomy …

Bitter Taste Preference And Psychopathy: A Partial Replication Of Sagioglou And Greitemeyer, 2016, Lauren A. Waymire

Honors Program Theses

In this study, we did a partial replication of Sagioglou and Greitemeyer’s 2016 study concerning bitter taste preferences and malevolent personality traits. Undergraduate students (n=40, mean age=19.40, 75% females) completed a laboratory component consisting of 24 samples of 8 different solutions (sucrose, sodium chloride, quinine, and citric acid with a higher and lower concentration of each) for 3 iterations, as well as PTC testing and tongue staining in order to count fungiform papillae. This was followed by a survey component that utilized HEXACO (which assesses six major domains of personality) and the IPIP-NEO scale for psychopathy (measured with the factors …

Integrating Genetics And Neuroimaging To Study Subtypes Of Binge Drinkers, Megan E. Cooke

Theses and Dissertations

Risky alcohol use is a major health concern among college students, with 40.1% reporting binge drinking (5 or more drinks in one occasion) and 14.4% reporting heavy drinking (binge drinking on 5 or more occasions) in the past month. Risky alcohol use is thought to be the result of a complex interplay between genes, biological processes, and other phenotypic characteristics. Understanding this complex relationship is further complicated by known phenotypic heterogeneity in the development of alcohol use. Developmental studies have suggested two pathways to risky alcohol use, characterized by externalizing and internalizing characteristics, respectively. However, the underlying biological processes that …

Cannabis Use Frequency And Mood On Creativity, Caitlin Clark

Cal Poly Humboldt theses and projects

This study examines the relationship between cannabis use (infrequent, moderate, and heavy use) and one’s mood (neutral, positive, and negative) on creativity. Folk ideas of creativity and the relationships between cannabis use and mood may not reflect the real relationship between these factors (e.g. regarding cannabis use, it is perceived to be linked with higher rates of creativity; regarding mood, negative states [i.e. tortured artist] are thought to fuel creativity). Although both cannabis use and mood have been found to influence creativity independently, the current study is unique in its aims to identify whether cannabis use and mood interact to …

Are Caffeine’S Effects On Neuronal Calcium Levels Due To The Caffeine Metabolite, Paraxanthine?, Kendra Jean Hartsuyker

Cal Poly Humboldt theses and projects

Caffeine has diverse effects on neurons including, potentially, protection against Parkinson’s-related neurodegeneration. Caffeine may protect neurons from damage by limiting mitochondrial membrane permeability through a calcium-dependent mechanism. This study was a first step investigating calcium’s role in caffeine neuroprotection in vivo using zebrafish larvae. Elavl3:GCaMP6s zebrafish, which express a genetically encoded fluorescent calcium indicator protein in most CNS neurons, received caffeine (0, 50, 125, 250 µM, bath applied) in an ascending dose series during fluorescence calcium imaging of a central catecholaminergic nucleus (a proposed zebrafish homolog of the locus coeruleus, a structure affected in Parkinson’s disease). Parallel experiments tested effects …

Restoration Of Attentional Deficits After Concussion, Katharine B. Earle

Cal Poly Humboldt theses and projects

Difficulties with concentration and attention are among the most prevalent symptoms experienced after concussion. Rest has been the most common form of recovery from concussion; however, new research is suggesting mild mental exertion to be an effective aid in recovery. Drawing from Attention Restoration Theory, this study evaluated the idea that cognitive engagement with natural environments can mitigate post-concussion directed-attention deficits. A between subjects repeated measures design was used to test directed-attention after video exposure to restorative/nature and nonrestorative/city environments. Measures of mood, connectedness to environment, and symptomology scores were also collected. No meaningful difference between exposure type was found …

An Investigation Of The Relations Between Stress And Prospective Memory, Brandon T. Stewart

Graduate Student Theses, Dissertations, & Professional Papers

Prospective memory (PM) is a future-oriented memory system that entails “remembering to remember” intentions, or to perform actions in the future. People spend significant portions of their day-to-day lives forming and acting on intentions, and the ability to successfully generate, retain, and complete these intentions has important implications for one’s daily functioning and quality of life. Another common human experience is stress, whether that be short-term, acute stress, or long-term, chronic stress. Despite the significance and ubiquity of both PM and stress, the research base documenting the relations between them is sparse. This topic area necessitates additional research to delineate …

The Impact Of Stress On Steroid Hormones And Cue Reactivity In Smokers And Gamblers, Stephanie Elaine Wemm

Legacy Theses & Dissertations (2009 - 2024)

Addictions, both substance and behavioral, have been conceptualized as having similar biopsychosocial processes with different opportunistic expressions (Shaffer et al., 2004). Biological processes such as the hormonal response to stress as measured by cortisol, dehydroepiandrosterone (DHEA), and the ratio of the DHEA/cortisol may be among the variables underlying the disposition to develop an addictive disorder, regardless of whether it is a substance-based or a so-called behavioral addiction. The current study aimed to examine whether physiological and psychological reactions to stress are similar in high-frequency smokers and gamblers. The subjective (urges, cravings) and physiological responses (skin conductance and heart rate) of …

The Effect Of Two Modes Of Aerobic Assessment On Fifth Grade Students' Self Efficacy, Debra Roth

Walden Dissertations and Doctoral Studies

Declining youth physical activity levels and lack of aerobic fitness have been well documented with a corresponding rise in obesity levels and health issues. Based on Bandura's social cognitive theory, healthy physical activity levels and aerobic fitness are strongly connected to positive physical activity self-efficacy beliefs. This study examined whether student physical activity self-efficacy, motivation, and effort were different for the FitnessGram-® (FG) 1-Mile Run when compared to the 15-minute Aerobic Assessment Based on Improvement (AABI). A concurrent mixed method quasi-experimental approach measured 5th grade students' physical activity self-efficacy beliefs through a pretest and posttest survey while aerobic assessment scores …

Characterization Of Sex Differences In The Reinforcing Effects Of Nicotine, Rodolfo Jesus Flores Garcia

Open Access Theses & Dissertations

It is presently unclear whether ovarian hormones, such as estradiol (E2) promote the reinforcing effects of nicotine in females. Thus, we compared extended access to nicotine intravenous self-administration (IVSA) in intact male, intact female, and OVX female rats (Study 1) as well as OVX females that received vehicle or E2 supplementation (Study 2). The E2 supplementation procedure involved a 4-day procedure involving 2 days of vehicle administration and 2 days of E2 administration. Two doses of E2 (25 or 250 ug) were assessed in separate groups of OVX females in order to examine the dose-dependent effects of this hormone on …

Differentiating The Effects Of Animal-Assisted Versus Equine Facilitated Psychotherapy On Positive Psychological Outcomes Through A Stress Induction Context, Catherine J.V. Jones

College of Graduate Studies: Theses & Dissertations

The unique benefits of Equine Facilitated Psychotherapy (EFP) such as the human-horse bond, a non-traditional therapy setting, and performing altruistic acts are thought to facilitate positive change in humans. One mechanism by which positive changes occur is through improved coping and resilience in the face of stress. To date, only a handful of correlational studies speak to the potential effects of EFP on resilience-based outcomes. Thus, this study sought to address this gap in the literature by exploring the benefits of EFP compared to traditional Animal Assisted Therapy (AAT) in an experimental context. Specifically, we examined the effects of different …

Sensory-Specific Satiety Is Intact In Rats Made Obese On A High-Fat, High-Sugar Choice Diet., Kevin P. Myers

Faculty Journal Articles

Sensory-specific satiety (SSS) is the temporary decreased pleasantness of a recently eaten food, which inhibits further eating. Evidence is currently mixed whether SSS is weaker in obese people, and whether such difference precedes or follows from the obese state. Animal models allow testing whether diet-induced obesity causes SSS impairment. Female rats (n = 24) were randomly assigned to an obesogenic high-fat, high-sugar choice diet or chow-only control. Tests of SSS involved pre-feeding a single palatable, distinctively-flavored food (cheese- or cocoa-flavored) prior to free choice between both foods. Rats were tested for short-term SSS (2 h pre-feeding immediately followed by 2 …

The Mediating Effects Of Cortisol On The Relationship Between Conscientiousness And Judgments Of Learning, Katherine D. Miller

Graduate Theses/Dissertations

Cortisol assists in facilitating stress response. A peak in cortisol levels can be seen between 20 and 40 minutes after exposure to the stressful event. Judgments of learning (JOLs) are within the field of metacognition and are judgments individuals make about how well they feel they have acquired the target information. Many factors influence the accuracy of these judgments, including whether they are immediate or delayed. Conscientiousness is a characteristic of personality that is associated with responsibility and organization. Individuals high in conscientiousness are more likely to have positive health related outcomes. A relationship between conscientiousness and the appraisal of …

Psychopathy And The Effect Of Imitation On Empathetic Pain, Emily N. Lasko

College of Graduate Studies: Theses & Dissertations

Psychopathy is a disorder largely characterized by a marked deficit in empathy, however, the specificity and extent of the deficit is currently unclear. While it has been well-established in the literature that individuals higher in psychopathy tend to have intact Theory of Mind abilities and exhibit a deficient ability for affective empathy (Blair, 2005), the contribution of motor empathy to these abilities, particularly in regard to empathy for pain, has yet to be experimentally examined. Additionally, the possibility of imitation increasing motor empathic abilities has not been tested in this capacity. The goal of the current study was to further …