Biological Psychology Commons^™

Neurostructural Organization And Neocortical Projecting Neuron Distribution In A Mouse Model Of Timothy Syndrome-Mediated Autism Spectrum Disorder, Aiden L. Ford

Honors Scholar Theses

Aims: This study investigates the nuanced effect of the CACNA1C mutation on neurocognition and neurodevelopment via an extended study of the Timothy Syndrome (TS) mediated Autism Spectrum Disorder (ASD) mouse model – TS2-neo. It includes: (1) an expanded assessment of the TS2-neo behavioral phenotype, and (2) a comprehensive histological analysis of cortical structural and laminar features.

Methods: 24 age-matched male mice – 12 TS2-neo (B6.Cg-Cacna1c^tm2Itl, knock-in G406R mutation), 12 WT (C57BL/6J) – were tested on paradigms examining motor, socio-communicative and cognitive abilities. Neural tissue was processed for either volumetric analysis through Nissl stain (8 TS2-neo, 8 WT) or …

Humor In Medicine: A Literature Review Of Humor’S Potential Therapeutic Value In Health Care, Weston Michael Grant

Psychological Science Undergraduate Honors Theses

Using humor and laughter within the health care field has the potential to be relevant to patients during treatment, to the patient-caregiver relationship, to the subjective well-being of health care providers, and to the environments’ (e.g., work settings) impact on group relationships (e.g., colleagues). A review of the literature examines how the psychological and physiological effects of laughter and humor within the human body impact health and well-being, how humor and laughter improve the patient-practitioner relationship, and if humor and laughter can potentially impact physician burnout. Several possible implications for these findings are discussed, such as professional medical comedians, improvements …

Sparking A Dolphin's Curiosity: Individual Differences In Dolphins' Reactions To Surprising And Expectation-Violating Events, Malin Katarina Lilley

Master's Theses

Non-scientific literature consistently describes dolphins as “curious animals,” but there has been little systematic research on curiosity in dolphins. Curiosity in humans and certain non-human animal species, including birds and non-human primates, has been studied by examining individual differences in exploration and reactions to novel stimuli. Additionally, research has explored how human infants and non-human animals react when an event violates their expectations. The present study explored dolphins’ reactions to spontaneously surprising and expectation-violating stimuli. The reactions of dolphins, 15 bottlenose (Tursiops truncatus) and 6 rough-toothed (Steno bredanensis), at Gulf World Marine Park were analyzed in …

Anxiety-Like Behaviors And C-Fos Expression In Adult Zebrafish: Effects Of Housing Conditions, Alcohol And Caffeine, Adam Douglas Collier

Dissertations

Alcohol abuse is the third largest risk factor for disease world, responsible for an estimated 3.3 million deaths each year. The concomitant ingestion of alcohol and caffeine is hypothesized to increase risk factors associated with alcohol use alone by reducing subjective effects of intoxication. The zebrafish (Danio rerio) has recently garnered attention from researchers as an effective pre-clinical in-vivo animal model in behavioral pharmacology research, largely due to small size, low-cost and ease of drug delivery. A number of studies have reported the effects of alcohol and caffeine on zebrafish behavior at a variety of doses. However, the …

Do Humans Prefer Faces? Zygomatic Muscle Responses To Neutral Faces Vs. Neutral Objects, Thomas J. Goetze

The Review: A Journal of Undergraduate Student Research

The present study examined the significance of viewing images of neutral faces versus images of neutral objects on zygomatic muscle activity using facial EMG. Participants (60% women) from a pool of introductory psychology courses had their facial EMG recordings measured in response to images of neutral faces and neutral objects. Participants’ valence rating of each image was also recorded using the Self-Assessment Manikin (SAM) in order to rate their emotional response to each image. The primary hypothesis was that participants would have greater activity in the zygomatic muscle region when presented with images of neutral faces as opposed to lessor …

Social Risks As Costly Trait Signals, Ruth E. Sarafin

Psychology ETDs

Costly signaling theory posits that people will sometimes engage in seemingly irrational behavior to show off attractive qualities about themselves. These behaviors may end in or incur a cost to the actor such that only individuals who are highly fit are able to succeed at the behavior, and therefore behavior success is an honest signal of fitness. Previous research has used costly signaling to explain human physical risk taking behaviors such as rock climbing, but the current study seeks to apply them to social risk taking, such as raising one’s hand in class. Should social risk taking prove to be …

Sexuality & Perspective, Emma Tabei, Emily Ellison, Tyrell J. Osborn, Ileana Garnand

Collin College Undergraduate Interdisciplinary Student Research Conference

Panel Chair: Whitney Pisani

Papers Presented:

"Siren's Song of Sapiosexuality" by Emma Tabei

Abstract: Gender and male and female communications is discussed just as much if not more than politics currently. As we get more and more interested in understanding communication between genders, perhaps we need to look at where we came from instead of guessing what will happen next. Homer's, "Odyssey," specifically the "Siren's Song," pits male and female gender roles and perspectives against each other resulting in an untraditional look at modern female and male communications far ahead of Homer’s time; departing from the stereotypical gender looking glass. …

Maternal Stress And Stress Symptomatology In Children, Emily Klipa

Undergraduate Distinction Papers

With stress being referred to as the “health epidemic of the 21^st century” by the World Health Organization, questions arise about not only how this epidemic affects adults, but also how stress may affect today’s children. Research indicates that stress impacting parents trickle down to children, and the effects can be palpable. In this study the author examined maternal stress as well as stress related symptoms and illnesses in their children. Participants are mothers of children age’s five to ten. The protocol included completion of a four part online survey addressing demographic information, perceived stress, and recent stressful life …

Cognitive Functioning During Conflict In Intimate Partner Relationships Between Traumatized And Non-Traumatized Samples, Kylie N. Coleman

Doctor of Psychology (PsyD)

Significant differences have been found in neural connectivity of the brain in frontal, central, temporal, and parietal areas of individuals who experienced childhood trauma compared to those who had not (Cook, Ciorciari, Varker, & Devilly, 2009). This study investigated the relationship between the number of distressing and traumatic life experiences and participants’ neural responses to observing simulated conflict in intimate relationship. Graduate students (n = 11) answered conflict resolution and emotional activation questions while watching a simulated, escalating marital conflict. The participants’ neural responses were recorded via EEG mean power data from frontal and temporal brain regions. Heart rate (bpm) …

Who's Tweeting Whom: The Influence Of Rearing Condition On Social Integration In Zebra Finches, Zachary L. Darwish

UNO Student Research and Creative Activity Fair

Zebra finches (Taeniopygia guttata) are a gregarious species of finch. Previous work with zebra finches has demonstrated the long-lasting impacts of ear social environment on social behavior in adulthood. Zebra finch chicks were raised by either both parents (biparental) or their mother only (uniparental) and their behavior in an aviary was recorded using passive integrative transponders. Zebra finch ID numbers were recorded every time they entered a feeding station for 31 days. There was a trend for uniparental birds to engage in more visits to a feeding station per event than biparental birds, however, there was no difference …

Neuroendocrine And Psychological Factors Associated With Burnout, Compassion Fatigue, And Reduced Compassion Satisfaction In Mental Health Professionals, Michelle Huffman

UNO Student Research and Creative Activity Fair

Mental health professionals are at increased risk for burnout, compassion fatigue, and reduced compassion satisfaction. Burnout is characterized by emotional exhaustion, depersonalization, and loss of personal accomplishment. Compassion fatigue is a more progressed disruption relative to burnout marked by insomnia/nightmares, arousal, loss of objectivity, isolation, and intrusive thoughts. Compassion satisfaction buffers against burnout and compassion fatigue. Although links between demographic, psychological, and biological factors have been documented, interactions between these factors have not been explored. Mental health professionals completed psychological inventories measuring depression, anxiety, burnout, compassion fatigue, and compassion satisfaction. Saliva samples were collected during the Trier Social Stress Test …

Neurotensin Nts1 And Nts2 Receptor Agonists Produce Anxiolytic-Like Effects In The 22-Khz Ultrasonic Vocalization Model In Rats, Floyd F. Steele Iii, Shannon C. Whitehouse, Jacob S. Aday, Adam J. Prus

Journal Articles

Neurotensin is a neuropeptide neurotransmitter that interacts with multiple neurotransmitter systems, including those regulating amygdalar function, via NTS₁ and NTS₂ receptors. Both receptors are expressed in the amygdala and agonists for NTS₁ or NTS₂ receptors have exhibited anxiolytic effects in animal models. Systemic adminstration of NTS₁ receptor agonist PD149163 was recently shown to reduce footshock conditioned 22-kHz ultrasonic vocalizations in rats, suggesting that PD149163 produced an anxiolytic effect. The effects that neurotensin may have or a selective NTS₂receptor agonist may have on 22-kHz vocalizations has yet to be examined. The current study evaluated …

Dopamine D1 And D3 Receptor Polypharmacology In Cocaine Reward And Cocaine Seeking, Ewa J. Galaj

Dissertations, Theses, and Capstone Projects

Background: In the search for efficacious pharmacotherapies to treat cocaine addiction much attention has been given to agents targeting D1 or D3 receptors because of the involvement of these receptors in cocaine-related behaviors. D1 and D3 receptor partial agonists and antagonists have been shown to reduce cocaine reward, reinstatement of cocaine seeking and conditioned place preference (CPP) in rodents and non-human primates. However, translation of these encouraging results with selective D1 or D3 receptor agents has been limited due to a number of factors including toxicity, poor pharmacokinetic properties and extrapyramidal and sedative side effects.

Purpose: Given the …

Capturing The Attention Of Caregivers: Variability In Infant Vocalizations, Catharine A. Castelluccio De Diesbach

Dissertations, Theses, and Capstone Projects

The effect of variability in infant vocalizations on potential caregivers’ heart rate variability (HRV), facial expressions, and subjective ratings on emotional reactions and desire to approach the baby was examined in an evolutionary context. Recordings of non-canonical, canonical, fussing, and crying vocalizations were utilized to elicit physiological and self-reported reactions from sixty participants. Breastfeeding mothers, non-mothers at high estradiol point in menstrual cycle, non-mothers at low estradiol point in menstrual cycle, fathers, and non-fathers were included in the study. Participants wore Polar RS800 heart rate monitors, were video recorded for facial expression analysis, and filled out 11 point self-rating forms …

Sex Differences In The Anxiety Effects Of Cannabinoids, Helen T. French

Dissertations, Theses, and Capstone Projects

Aim: Anxiety disorders are twice as common among women, and those with anxiety disorders are 2-3 times more likely to have a substance abuse disorder than the general populace. However, little data exists on the sexually dimorphic effects of cannabinoids. In male humans and rodents, low acute doses of cannabinoids are anxiolytic while high and/or chronic doses are anxiogenic. In the dose response curve (DRC), we examined whether the biphasic effects of cannabinoids observed in males are also present in females. In the CB1R antagonism study, CP55,940-induced CB1R activation was antagonized via the CB1R-selective antagonist rimonabant to test the hypothesis …

Estradiol, Substance P, And The Pi3k-Akt-Mtor Pathway In The Dorsal Horn Of The Spinal Cord During Inflammatory Pain, Zane Ferguson

Dissertations, Theses, and Capstone Projects

Pain is a critical survival mechanism that signals potential or actual damage, but it can become pathological when it persists beyond the injury. Chronic pain is a major health issue that affects 10-20% of the adult population and is found disproportionately in women. There are numerous, interacting mechanisms underlying this phenomenon. This study used female rats to investigate the impact of estrogens on sensory signaling by substance P, a neuropeptide that contributes to the development of chronic pain, and the PI3K-Akt-mTOR pathway, an intracellular mechanism of nervous system plasticity.

The Potential Of Epigenetics Research To Transform Conceptions Of Phenotype Development, David S. Moore

Pitzer Faculty Publications and Research

Epigenetics remains an exciting subdiscipline of biology, generating discoveries and insights about development. Because epigenetic phenomena can draw attention to the dynamic, interactional, and probabilistic nature of phenotype development, epigenetics research could hasten the demise of both nature-nurture debates and reductionist, genetically determinist perspectives on phenotype development. However, new data alone will not inevitably transform conceptualizations of phenotype origins, because it remains possible to assimilate epigenetic phenomena into traditional conceptual frameworks; epigenetic discoveries could even strengthen biologically determinist conclusions if traditional conceptualizations are retained. Although epigenetics will not force conceptual transformation, epigenetics research encourages the dismissal of the nature-nurture dichotomy …

Sensory-Specific Satiety Is Intact In Rats Made Obese On A High-Fat, High-Sugar Choice Diet., Kevin P. Myers

Faculty Journal Articles

Sensory-specific satiety (SSS) is the temporary decreased pleasantness of a recently eaten food, which inhibits further eating. Evidence is currently mixed whether SSS is weaker in obese people, and whether such difference precedes or follows from the obese state. Animal models allow testing whether diet-induced obesity causes SSS impairment. Female rats (n = 24) were randomly assigned to an obesogenic high-fat, high-sugar choice diet or chow-only control. Tests of SSS involved pre-feeding a single palatable, distinctively-flavored food (cheese- or cocoa-flavored) prior to free choice between both foods. Rats were tested for short-term SSS (2 h pre-feeding immediately followed by 2 …

The Mediating Effects Of Cortisol On The Relationship Between Conscientiousness And Judgments Of Learning, Katherine D. Miller

Graduate Theses/Dissertations

Cortisol assists in facilitating stress response. A peak in cortisol levels can be seen between 20 and 40 minutes after exposure to the stressful event. Judgments of learning (JOLs) are within the field of metacognition and are judgments individuals make about how well they feel they have acquired the target information. Many factors influence the accuracy of these judgments, including whether they are immediate or delayed. Conscientiousness is a characteristic of personality that is associated with responsibility and organization. Individuals high in conscientiousness are more likely to have positive health related outcomes. A relationship between conscientiousness and the appraisal of …

Bitter Taste Preference And Psychopathy: A Partial Replication Of Sagioglou And Greitemeyer, 2016, Lauren A. Waymire

Honors Program Theses

In this study, we did a partial replication of Sagioglou and Greitemeyer’s 2016 study concerning bitter taste preferences and malevolent personality traits. Undergraduate students (n=40, mean age=19.40, 75% females) completed a laboratory component consisting of 24 samples of 8 different solutions (sucrose, sodium chloride, quinine, and citric acid with a higher and lower concentration of each) for 3 iterations, as well as PTC testing and tongue staining in order to count fungiform papillae. This was followed by a survey component that utilized HEXACO (which assesses six major domains of personality) and the IPIP-NEO scale for psychopathy (measured with the factors …