Biological Psychology Commons^™

Diurnally Active Rodents For Laboratory Research, Roberto Refinetti, G. J. Kenagy

Psychological Sciences Faculty Publications and Presentations

Although inbred domesticated strains of rats and mice serve as traditional mammalian animal models in biomedical research, the nocturnal habits of these rodents make them inappropriate for research that requires a model with human-like diurnal activity rhythms. We conducted a literature review and recorded locomotor activity data from four rodent species that are generally considered to be diurnally active, the Mongolian gerbil (Meriones unguiculatus), the degu (Octodon degus), the African (Nile) grass rat (Arvicanthis niloticus), and the antelope ground squirrel (Ammospermophilus leucurus). Our data collected under 12L:12D light-dark cycles confirmed and expanded …

The Influence Of Depressive Symptoms On Frn Amplitude: An Eeg Study, Jonathan Burton

USC Aiken Psychology Theses

Background: Individuals diagnosed with depression demonstrate differences in neural activation patterns detectable using electroencephalogram (EEG). One of these differences has been specifically linked with the event-related potential (ERP) component called feedback-related negativity (FRN). In participants diagnosed with depression, the FRN has been shown to have larger amplitudes in response to negative feedback. However, previous research has only specifically looked at the difference of this amplitude between groups, specifically those with and those without a diagnosis of depression. Objective: The goal of the current study was to examine whether a continuous range of depressive symptoms in participants can predict FRN amplitudes, …

Effects Of Naltrexone On Alcohol And Nicotine Use In Female P Rats, Usman Z. Hamid, Michael T. Bardo Ph.D.

Posters-at-the-Capitol

Title: Effects of Naltrexone on Alcohol and Nicotine Use in Female P Rats

Author: Usman Z. Hamid, Department of Psychology, University of Kentucky

Faculty Mentor: Michael T. Bardo, Ph.D., Department of Psychology, University of Kentucky

Alcohol is the most commonly abused substance worldwide. It is often co-abused with nicotine, which increases the difficulty of cessation of both alcohol and nicotine. Despite having similar mechanisms of action, there is no single medication to treat the co-abuse. The objective of the current study is to analyze the effects of the opiate antagonist naltrexone on alcohol consumption and the co-use of alcohol and …

Diversity And Inclusion In The Science Classroom, Sowmya Anjur

Faculty Publications & Research

A Diversity, Epidemiology and social justice unit was incorporated into the Physiology and Disease curriculum in Fall 2016. Students discussed topics such as social and cultural influences on diversity thinking, and selective treatment in hospitals based on race. It was very noteworthy that students were united in their thinking regarding diversity and inclusion, despite the fact that they were from different backgrounds and diverse cultures. In 2017, additional discussions were held on equity in education. Students who were otherwise reserved were encouraged enough to express their views, and everyone appreciated the fact that they had been included.

Temporal Information Guides Prefrontal Preparatory Activity, Jacqueline R. Janowich

Shared Knowledge Conference

Proactive preparation for an upcoming goal differs from last-minute reactive adaptation, but it is unclear how preparatory mechanisms change based on when in the future a goal needs to be executed. To assess how timing information is integrated into preparatory control, we designed a novel variant of the Dot Pattern Expectancy task, where each cue signaled both task rule and delay duration (known short, known long, or unknown) between cue and probe. We recorded EEG while healthy young adult participants (n=36) performed this task, and found that delay demands elicited distinct prefrontal preparatory activities. Medial prefrontal amplitude was sensitive to …

Electrocortical Responses During Script-Driven Emotional Imagery, Nicholas Best, Cassandra Gonzalez, David Herring Ph.D.

Scholars Week

Emotional imagery is a common induction technique used in the laboratory and also employed in various exposure therapy treatments across the anxiety spectrum (e.g., specific and social phobias). Despite its clinical uses, there is a surprising dearth of literature regarding the basic central neural processes underlying emotional imagery, though other peripheral physiological processes have been investigated extensively using heart rate, skin conductance, and startle-blink responses. One imagery study that used a central nervous system psychophysiological measure -event specific brainwave or the event-related potential (ERP) technique- suggests the late positive potential (LPP) of the ERP is larger for unpleasant versus neutral …

Common Sense And Common Nonsense: A Conversation About Mental Attitudes, Science, And Society, Daniel S. Levine

Psychology Faculty Publications - Archive

Daniel S. Levine's Common Sense and Common Nonsense observes human decision making, ethics, and social organization as illuminated by the scientific disciplines of neural network theory, neuroscience, experimental psychology, and dynamical systems theory. It is a book whose aim is advocacy as well as research. Its goal is to use an understanding of our brains and minds to better operationalize Aldous Huxley's admonition to "try to be a little kinder." It wanders over examples from sociology, politics, economics, religion, literature, and many other fields but looks at all as examples of a few common themes. The "common nonsense" of the …

Validation Of The Barkley Deficits Of Executive Functioning Scale-Short Form, Brian Sheble

Dissertations

The Barkley Deficits of Executive Functioning-Short Form (BDEFS-SF) is a short rating scale measuring executive functioning in adults. The BDEFS-SF was developed using the 5 highest loading questions from the BDEFS-LF. Consequently, the psychometric qualities of the BDEFS-SF were not investigated using formal methods. In this study, the psychometric attributes of the BDEFS-SF were examined using two separate but similar groups. The first group of 264 men and women aged 18-35 years old completed the BDEFS-SF via an internet survey. The second group of 36 men and women aged 18-35 years old completed the BDEFS-SF and individualized assessments of executive …

Evidence-Based Teaching Strategies For Behavioral Neuroscience And Biological Psychology Classes, Richard Addante

Q2S Enhancing Pedagogy

Courses in Behavioral Neuroscience and Biological Psychology were taught while implementing evidence based teaching practices and several additional innovations. Students engaged in think-pair-share activities, group projects, and novel innovations of assignments including incentivized exam re-earns and creating modern memes of neuroscience content. Students exhibited evidence of learning, enjoyment, and teaching effectiveness.

Cannabinoid-Induced Behavioral Sensitization In Adolescent Sprague-Dawley Rats, Michelle Stone

Electronic Theses, Projects, and Dissertations

Adolescent cannabis use has grown because of increased availability and higher societal acceptance. This increase in cannabis use is problematic as adolescents who experiment with cannabis are more likely to abuse cannabis and experiment with other illicit drugs such as cocaine. The reason for the greater susceptibility to drugs use is unclear and may be the result of altered drug sensitivity after cannabis exposure. Thus, the present investigation used the behavioral sensitization paradigm to examine the behavioral response of early adolescent rats to the cannabinoid agonist CP 55,940 (CP) or cocaine after repeated cannabinoid administration. It was hypothesized that: (1) …

Positive Affect And Health: What Do We Know And Where Next Should We Go?, Sarah D. Pressman, Brooke N. Jenkins, Judith T. Moskowitz

Psychology Faculty Articles and Research

Positive affect (PA) is associated with better health across a wide range of physical health outcomes. This review reflects on why the study of PA is an essential component of our understanding of physical health and expands on pathways that connect these two variables. To encourage forward movement in this burgeoning research area, measurement and design issues in the study of PA and health are discussed, as are the connections between PA and a range of different health outcomes. Plausible biological, social, and behavioral pathways that allow for positive feelings to get under the skin and influence physical wellness are …

Efficaciousness Of Mindfulness Interventions For Trauma Using Psychophysiological Measures: A Review, Sherief Y. Eldeeb

Scholarly Undergraduate Research Journal at Clark (SURJ)

In recent decades the efficaciousness of mindfulness has been proven in a wide variety of contexts, but some crucial populations remain understudied. This review critically examines the literature on mindfulness in individuals with trauma using psychophysiological measures. Psychophysiological measures offer critical insight into this intersection of mindfulness and trauma due to the known somatic components in each, as well as serving as an objective response. Mindfulness-based treatments seem to show great promise in treating trauma, however there are significant limitations in the literature. Future studies should standardize the minimum length of treatment, utilize gender-balanced and ethnically diverse samples, and introduce …

The Effect Of A Voice Treatment On Facial Expression In Parkinson’S Disease: Clinical And Demographic Predictors, Amanda D. Bono

Dissertations, Theses, and Capstone Projects

Parkinson’s disease (PD) is a neurodegenerative disease associated with a wide range of motoric, cognitive, and behavioral symptoms. Impairments in facial mobility and emotional expressivity are common and can impair communication, in turn, affecting daily functioning and quality of life. Previous research suggests that the Lee Silverman Voice Treatment © (LSVT LOUD; Ramig et al., 2001, 2011) increases vocal loudness and facial expressivity in individuals with PD compared to PD and healthy controls. This study extends the literature by examining the effects of LSVT and an articulation-based control treatment (i.e., ARTIC) on multiple aspects of facial expressivity (i.e., emotional frequency …

The Relationship Between Cognitive And Neural Bases Of Metamemory Judgments, Alexandra M. Gaynor

Dissertations, Theses, and Capstone Projects

Metamemory monitoring, the process of making subjective assessments of the status of one’s own memory, is crucial to guiding behavior and effective learning. Past cognitive research has shown that subjective confidence judgments are inferential in nature, and based on cues available at the time of the judgment. When confidence is based on cues that are related to objective memory performance, metamemory accuracy is high. However, past studies have shown that metamemory monitoring tends to be inaccurate because individuals base their confidence on information that is not predictive of memory success, such as the fluency with which items were encoded during …

Dietary Curcumin Promotes Resilience To Chronic Social Defeat Stress In A Highly Susceptible Mouse Strain, Antonio V. Aubry

Dissertations, Theses, and Capstone Projects

Chronic exposure to stress is a risk factor for the development of major depression and post traumatic stress disorder in humans and induces depressive- and anxiety-like phenotypes in rodents. However, there are few pharmacological interventions available that effectively treat maladaptive responses to chronic stress in the clinical setting. One therapeutic agent that has recently shown promise in treating psychiatric disorders is curcumin, a yellow-pigmented polyphenol compound found in the turmeric plant. Curcumin has been shown to prevent the development of stressed-induced depressive-like behavior in rodents and reduce symptoms of depression in clinically diagnosed patients. In this dissertation, I investigated whether …

Curcumin Inhibits The Ikk:Nf-Kappa B Pathway In Neural Fear Circuits, Miguel A. Briones

Dissertations, Theses, and Capstone Projects

The study of how the brain acquires fearful memories has attracted considerable experimental attention, due in part to the promise of discovering novel therapeutic approaches for psychiatric disorders that are characterized by unusually strong and persistent traumatic memories. In recent years, extensive research has focused on studying the neural and molecular mechanisms by which fear memories are acquired, stored, and retrieved in the brain. Once acquired, fear memories may be attenuated using one of 2 procedures: 1) fear extinction, which involves repeated presentation of the fear-arousing stimulus in the absence of an aversive consequence, or 2) interference with the reconsolidation …

A Functional Neuroimaging Study Of Self-Regulatory Control In Adults With Gambling And Obsessive-Compulsive Disorders, Nidhi Parashar

Dissertations, Theses, and Capstone Projects

Objective: Recent findings suggest phenomenological similarities across gambling and obsessive-compulsive disorders. The key similarity between the disorders is the failure to inhibit or control a repetitive behavior (or urges to engage in a behavior) and intrusive thoughts. Our current understanding of the neural pathophysiological mechanisms linking gambling and obsessive-compulsive disorders is limited. Thus, the aim of the present study was to examine the functioning of frontostriatal brain regions that support self-regulatory control in adults with gambling and obsessive-compulsive disorders.

Methods: The study compared functional magnetic resonance imaging blood oxygen level dependent response in 19 adults with pathological gambling (PG), …

Wellness And Karate, Cristina Kumpf

Electronic Theses and Dissertations

The promotion of wellness is an integral part of the counseling field and is considered to be a central focus to the counseling process (Barden, Conley, & Young, 2015; Myers, 1992). The counseling profession adopted the concept of wellness because it harmonizes with many of the founding principles of the ACA and is seen as a process of questing toward optimal health and well-being in body, mind, and spirit (Barden, Conley, & Young, 2015; Myers, 1992; Myers, Sweeney, & Witmer, 2000). Additionally, ACA Code of Ethics (2014) state that counselors “engage in self-care activities to maintain and promote their own …

Yardwork: A Biography Of An Urban Place By Daniel Coleman, Vivian M. Hansen

The Goose

Review of Daniel Coleman's Yardwork: A Biography of an Urban Place.

Developmental Seizures And Mortality Result From Reducing Gabaa Receptor Α2-Subunit Interaction With Collybistin, Rochelle M. Hines, Hans Michael Maric, Dustin J. Hines, Amit Modgil, Patrizia Panzanelli, Yasuko Nakamura, Anna J. Nathanson, Alan Cross, Tarek Deeb, Nicholas J. Brandon, Paul Davies, Jean-Marc Fritschy, Hermann Schindelin, Stephen J. Moss

Psychology Faculty Research

Fast inhibitory synaptic transmission is mediated by γ-aminobutyric acid type A receptors (GABAARs) that are enriched at functionally diverse synapses via mechanisms that remain unclear. Using isothermal titration calorimetry and complementary methods we demonstrate an exclusive low micromolar binding of collybistin to the α2-subunit of GABAARs. To explore the biological relevance of collybistin-α2-subunit selectivity, we generate mice with a mutation in the α2-subunit-collybistin binding region (Gabra2-1). The mutation results in loss of a distinct subset of inhibitory synapses and decreased amplitude of inhibitory synaptic currents. Gabra2–1 mice have a striking phenotype characterized by increased susceptibility to seizures and early mortality. …