Physiology Commons^™

Comparing The Effect Of Hyposalinity On The Clearance Rate Of The Invasive Mussel Mytilus Galloprovincialis From Marina Del Rey And The Native Mussel Mytilus Trossulus From Coos Bay, Or, Lainee Irribarren, M. Christina Vasquez

Honors Thesis

Salinity is a key environmental factor that influences the physiology and distribution of intertidal mussels. Climate change is predicted to increase freshwater runoff and intensify hyposaline stress in coastal habitats. Previous research has established the mussel Mytilus trossulus as more hyposaline tolerant compared to its competitive congener M. galloprovincialis, however the physiological responses underlying this tolerance have not been studied. Thus, this study examined how reduced salinity affects clearance rate, a measure of feeding performance, in the invasive mussel M. galloprovincialis from Marina del Rey, CA and the native mussel M. trossulus from Coos Bay, OR. I hypothesized that clearance …

Validating Endosomal Antibodies For Use In Immunofluorescence Assays In A Cell-Based Model Of Prader Willi Syndrome, Hayden O'Dell

Miners Solving for Tomorrow Research Conference

Prader-Willi syndrome (PWS) is a rare progressive metabolic disease characterized by a wide range of behavioral and cognitive defects, most notably severe hyperphagia. The disorder is caused by the complete loss of some paternally inherited genes on chromosome 15q11-q13, resulting in endocrine dysfunction and a loss of control over feeding behaviors. Among the deleted genes within this region is MAGEL2. Our lab recently characterized a paternally deficient MAGEL2 rat model of PWS, discovering a defect in pituitary secretory capacity that is consistent with the impaired vesicular trafficking and secretion observed in PWS patients. To further characterize the defects in vesicular …

Contrast Therapy Is Associated With Higher Thermal Comfort For A Similar Acute Inflammatory Response Compared With Sauna Therapy, Rene Barbier, Benjamin Enslow, Jace Nicolet, Louis Hein, Kelvin Wu, Sven Hoekstra

Posters - 2026

Passive heat therapy, through sauna or hot water immersion, can improve cardiometabolic health outcomes. An increasingly popular thermal modality is contrast therapy, during which sauna therapy is interspersed with cold exposure. However, the acute physiological and perceptual responses to contras therapy in  comparison with traditional sauna remains unknown. This study compared the acute inflammatory, physiological, and perceptual responses to contras against heat therapy in predominantly young, healthy individuals

Impact Of Liver-Secreted Small Extracellular Vesicles On Myotube Funcation, Tatiana Barrantes, Ioannis Tsialtas, Qing Zhang, Kevin Koronowski

Posters - 2026

Extracellular vesicles (EVs) mediate intercellular communication by transferring molecular signals between tissues. Liver-derived EVs contribute to metabolic regulation and have been implicated in tissue cross-talk during health and disease. Skeletal muscle is a highly metabolic tissue that depends on mitochondrial respiration for energy production. However, whether liver-secreted EVs influence myotube mitochondrial function remains unclear. Here, we investigate the impact of liver-derived EVs on myotube mitochondrial respiration.

An Investigation In The Physiological Effect Of Microplastic And Chemical Mixtures In The Body Length Of C. Elegans, Gregory Guantos, David M. Mares, Jennifer C. Harr Phd

Posters - 2026

• Microplastics (MP) are pieces of plastic less than 5 micrometers (mm). Microplastics are found in our environment and have even been found in the food humans consume, including in drinks from plastic bottles (Hu 2020).

• Di-butyl Phthalate (DBP) is a chemical known as a plasticizer commonly used in PVC applications, ink, fragrances, and adhesives

• Di-butyl Phthalate has been found to have negative effects on the physiological length of C. elegans (Xiyan 2018)

• Microplastics have similarly been found to decrease the physiological length of C. elegans (Schöpfer 2020)

• The combined effects of MPs and DBP include …

Short Lab Report- Presentation, Wroud Saleh, Yevgeniy Grigoryev

Open Educational Resources

No abstract provided.

Effects Of Dietary Nitrate And Caffeine On End Power And Work Above End Power During A 3 Min All-Out Test In Trained Male Cyclists, Anthony M. Hagele, Kyle Sunderland, Petey W. Mumford, Chad Kerksick

Faculty Scholarship

Background: The purpose of this study was to examine the effects of acute dietary nitrate (NO3−) and caffeine (CAF) supplementation on end power (EP) and work performed above EP (WEP) in trained male cyclists during a 3 min all-out test (3MT) on a cycle ergometer.

Methods: Fifteen healthy, trained male cyclists (28.5 ± 5.3 years, 79.2 ± 9.1 kg, VO2peak 55.2 ± 5.6 mL·kg−1·min−1) completed four exercise trials in a randomized, double-blind, placebo-controlled, crossover study design separated by 3–7 days. The four experimental conditions were placebo beverage (nitrate-depleted) + placebo capsule, nitrate-rich beetroot juice + placebo capsule (BR), …

Life Line Spring 2026, Jonathan Atwood

Life Line - The Biology Department Newsletter

In This Issue:

Greetings and Farewell: Part Deux; Signs for Trees; Passing of Dr. Mary Gahbauer: a Beloved Friend and Colleague; Dr. Lisa Marr Retires; The Department Welcomes Dr. Ann Feke; Dr. Kevin Svitana Retires; Ms. Donna Rhodeback Retires; Tucker Adds Swan Specimen to Otterbein's Collection; An UnbeLEAFable Year for the Otterbein Chapter of Botanical Society of America; Field Geology Course Visits Death Valley and Beyond; Agar Art: An Unexpected Canvas; Dr. Kevin Svitana Wins the Anderson Award for Outstanding Contribution to Groundwater Research; Introducing Opi: A New Face for Zoo and Conservation Ambassador Work; Michael Hoggarth, Professor Emeritus, Wins …

Muscular Degeneration In Caenorhabditis Elegans By Microplastic And Chemical Exposure Through Locomotion Analysis, Juan Pablo Olvera Rodriguez, Angelica Cue-Leon, David Mares

Posters - 2026

We use Caenorhabditis elegans (C. elegans) as a model organism to investigate the effects of microplastic and chemical exposure on muscle structure and function.

• Microplastics (MP) are pieces of plastic less than 5 μm, and Nanoplastics (NP) are less than 1 μm. Microplastics are man-made pollutants and have been found in the environment and in the food and water sources, including drinks from plastic bottles (Hu, 2020). • Our work relates environmental contamination to potential biological consequences at the muscular level, providing insight into how pollutants may contribute to degenerative damage.

• Polystyrene (PS) MPs alone and combined with …

Electromyography, Prosthetic Properties, And Running Biomechanics In Recreationally Active Persons With Lower Extremity Amputation, Paige M. Agnew

Rehabilitation Sciences Theses & Dissertations

Lower extremity loss affects nearly 150,000 individuals in the United States yearly yielding extreme health care costs annually. Typically, prosthetic devices are prescribed for 5-8 years despite known changes to an individual’s gait as time progresses. Patients can expect to undergo approximately 8-12 weeks of gait retraining to improve their comfort and efficiency. Biomechanical changes occur when running with a specific running prosthetic including considerable biomechanical and neuromuscular interlimb asymmetries and alterations in loading patterns. The purpose of this dissertation was to investigate the biomechanical demands for lower extremity prosthesis users during running. The first study synthesized peer reviewed evidence …

Evaluating Forearm Strength Variability In Collegiate Tennis Players Over The Course Of A Competitive Season, Jeffrey Williams, Payton Jensen, Kevin Laudner

Clinical Practice in Athletic Training

The muscles of the forearm undergo routine, forceful, and repetitive contractions while playing tennis and may experience adaptive changes that can precede injury. An understanding of forearm strength profiles of tennis players following a competitive season would assist clinicians’ evidence-based management of the forearm’s readiness for training, competition, and return-to-sport participation. Therefore, the purpose of this study was to explore the effects of a competitive tennis season on forearm strength among collegiate tennis athletes. A prospective, case-series design was used to examine a convenience sample of 15 asymptomatic NCAA Division I tennis players (males = 10, height = 182.88 [SD …

Acute Management Of A Hamate Fracture In A Collegiate Baseball Player: A Disablement Model Case Study, Kayleigh A. De Koker, Cory E. Barton, Lindsey E. Eberman

Clinical Practice in Athletic Training

The purpose of this disablement model case study was to outline a collegiate baseball player with an isolated hamate fracture including the injury evaluation, diagnosis, and acute management. During a tournament game, the collegiate career of the patient ended abruptly following an injury sustained while at bat. The patient attempted to bat again but encountered significant difficulty due to the increasing pain in his hand. Consequently, the athletic trainer was called out for an on-field examination. The patient presented with no edema or ecchymosis but severe pain in the hypothenar eminence. This patient also presented with decreased grip strength with …

Quality Of Athletic Training Services For Lower Extremity Injuries, Katie Sniffen, Michael Rozier, Katherine Stamatakis, Paula Buchanan, Janet E. Simon, Leslie Hinyard

Clinical Practice in Athletic Training

The use of patient-reported outcomes in athletic training is inconsistent, limiting the ability to communicate service quality and value to key stakeholders. The objective of this study is to calculate meaningful quality outcome measures for athletic training services for lower extremity injuries in high school student-athletes. Data were collected from a subset of the National Athletic Treatment, Injury and Outcomes Network Surveillance Program and a convenience sample of high school student-athletes with patient-reported outcome measures for lower extremity time-loss injuries. Failure-toprogress proportions (FTPPs) were calculated using the Knee Injury and Osteoarthritis Outcome Score (KOOS) for knee/thigh injuries and the Foot …

Recurrent Urinary Tract Infections In An Elite Level Diver: A Disablement Model Case Study, Matt O'Sullivan, Dominique M. Stevens, Lindsey E. Eberman

Clinical Practice in Athletic Training

This article presents a case of complicated and recurrent pyelonephritis, an infection of 1 or both kidneys, in an elitelevel diver. Urinary tract infections (UTIs) are among the most common outpatient infections in the United States; most are uncomplicated and resolve without significant mortality or morbidity. However, UTIs have the potential to present significant clinical challenges if the UTI becomes complicated or recurrent. Additionally, recurrent UTIs can carry a significant burden to both the individual patients and the larger healthcare system. The current paper reviews the epidemiological literature surrounding UTIs, the significant impact they have on a patient’s health-related quality …

Comfort Level Of Collegiate Student-Athletes In Opposite And Same-Gender Patient/Provider Relationships In Athletic Training, Samantha Dickie, Yashu Tang, Sydney Nelson, Emily Madrak

Clinical Practice in Athletic Training

Gender-based comfort in patient-provider relationships is a vital aspect of athletic training care. As the profession continues to evolve—particularly with a growing number of women athletic trainers (ATs) and progression of athletic training curriculum—it is essential to understand how gender dynamics influence the comfort of collegiate athletes when receiving care. This cross-sectional survey study examined how athlete comfort varies when treated by same- versus opposite-gender ATs in general patient care and in pathology-based scenarios. Ninety-six collegiate student-athletes (62.5% female) with the mean age of 20.26 (SD 1.7) years from NCAA and NAIA institutions completed the Gender Comfort with Athletic Trainer …

Prescribed Aerobic Exercise And Sport-Related Concussion Recovery: A Validation Case Series, Lacy L. Chapel, Tamara C. Valovich Mcleod

Clinical Practice in Athletic Training

Active rehabilitation, including prescribed sub-symptom threshold aerobic exercise implemented during the acute phase of recovery after sport-related concussion, has been shown to facilitate recovery and reduce the risk of persisting postconcussion symptoms. The purpose of this validation case series was to evaluate currently available external evidence regarding the effects of prescribed aerobic exercise interventions on recovery after sport-related concussion. For this study, the patient population included college athletes diagnosed with a sport-related concussion who participated in at least 5 days per week of supervised, prescribed aerobic exercise, based on graded aerobic exercise testing and heart rate threshold. Our study findings …

Suture Augmentation With Ucl Repairs In Baseball Pitchers As An Alternate To Reconstructions: An Evidence-To-Practice Review, Kayleigh A. De Koker, Kenneth E. Games

Clinical Practice in Athletic Training

An injury to the ulnar collateral ligament (UCL) is sustained through repetitive valgus motions, increasing in prevalence across all levels of baseball due to the increasing workload demands placed on the medial elbow in pitching. Traditionally, UCL tears have been managed through reconstructions followed by a lengthy rehabilitation process. In recent years, the UCL repair with suture augmentation has gained favor given the enhanced patient and clinician outcomes in return-to-play timelines, decreased medial gapping, improved Kerlan Jobe Orthopedic Clinic (KJOC) scores, and long-term functionality. Utilizing 4 databases (MEDLINE, Embase Cochrane library, Science Direct, and Scopus), literature was obtained addressing the …

Comparison Of Vibrating And Non-Vibrating Foam Roller On Hamstring Range Of Motion, Rakhoon Sung, Portia B. Resnick, Karen G. Roos, Mimi Nakajima

Clinical Practice in Athletic Training

Tightness in the distal hamstring is a common complaint among active individuals. While a foam roller is used to release muscle tension, there are limited studies about the effect using a vibrating foam roller (VFR) on hamstring flexibility and knee range of motion (ROM). For this reason, the purpose of the research was to compare the effect of a VFR and nonvibrating foam roller (NVFR) on hamstring flexibility and knee ROM in active college students. It was hypothesized that there would be more improvement in hamstring flexibility and knee ROM with a VFR than an NVFR. A randomized controlled trial …

A Review Of Mentorship And Recruitment Strategies For Minority Athletic Training Students, Dariana M. Brown

Clinical Practice in Athletic Training

The underrepresentation of minority athletic trainers remains a critical issue, affecting both the profession and the quality of patient care. While patient demographics continue to diversify, the athletic training workforce has not kept pace, leading to potential communication barriers, mistrust, and inadequate culturally competent care. This review examines whether culturally tailored mentorship programs and targeted recruitment initiatives improve retention, career satisfaction, and diversity in athletic training compared to standard methods. By analyzing studies on underrepresented minority students in athletic training, the review highlights key institutional barriers and systemic factors impacting recruitment and retention. Findings suggest that tailored mentorship and supportive …

Dietary Selenium Supplementation Modulates Proliferative Gene Regulators Through Attenuating Cell Cycle Inhibition On Late G1/S Transition In Pre-Pubertal Goat Testis, Muhammad Awais Soomro, Moolchand Malhi, Tarique Ahmed Khokhar, Faiz Muhammad Khand, Zafar Ali Khoso, Maria Sardar, Muhammad Mohsen Rahimoon, Awais Bin Shahid, Muhammad Anees Memon, Nabi Bux Solangi, Jawed Ali Dhiloo

Journal of Bioresource Management

Selenium (Se) is essential for normal gonadal improvement in prepubertal male goat. Thus hypothesized that dietary Se may influence late G1/S through M-phase gene networks in the testis, thereby advancing pre-pubertal testicular development via attenuation of inhibitory signals and modulation of late G1 cell-cycle regulators. The total of twenty animals, male goats (3 months old) weighing ~11 kg were arbitrarily given to a basal diet (Control; C, n = 10) or the same diet plus Se-yeast (SY; 0.3 mg/kg; n = 10) for 10 weeks. Basal Se concentration in control diet was 0.037 mg/kg (ICP‑OES Optima 2100‑DV, PerkinElmer). Transcript analysis …