A Series Of Investigations On The L. Cornutus Host System And Bivesiculid Sp. Cercariae, Briana K. Zaffiro

All HCAS Student Capstones, Theses, and Dissertations

Rising global temperatures are likely modulating parasite-host interactions, yet the direction and magnitude of these changes remain uncertain. Rarely are these interactions viewed from both a host and parasite perspective. Using both CT_max, or Critical Thermal Maximum, and Clark-type polarographic oxygen microelectrodes, the physiological metabolic effects are investigated. CT_max is examined in Common Shiners, Luxilis cornutus, and is shown to be modulated by parasitism: uninfected fish had the highest CT_max average of 37.0°C, whereas heavily infected fish had decreased CT_max averaging 35°C. Prior to the parasite metabolic investigation, a suitable medium was determined, as …

The Beat Behind The Bark: Investigating The Effects Of Music Tempo On Canine Physiological And Psychological States, Marley Lanier

Poster Presentations

Music is a universal component of human culture that has been demonstrated influencing emotional, cognitive, and physiological responses, specifically heart rate and hormonal responses (Mehr et al., 2019; Trappe, 2012). Recently, this research has expended to explore how music may affect non-human animals, particularly dogs, due to their roles as therapy animals, service animals, and human companions (Lindig et al., 2020; Gee et al., 2021). Being able to understand how music influences canine stress and relaxation hold important applications in environments such as shelters, veterinary clinics, and at home. One important feature of music is tempo, or beats per minute …

Morphological Variation Of Lingual Glands In Wild American Alligator (Alligator Mississippiensis) Populations, Benjamin Angalet

Master's Theses

American alligators (Alligator mississippiensis) inhabit diverse aquatic ecosystems including freshwater wetlands, swamps, and estuarine rivers. As apex predators, their physiological resilience has implications for ecosystem stability and long-term conservation. With projected sea-level rise and increasing saltwater intrusion into coastal freshwater habitats, understanding the osmoregulatory capacity of alligators is increasingly important. Unlike marine-tolerant crocodilians such as the saltwater crocodile (Crocodylus porosus), which possess specialized salt-secreting lingual glands in addition to renal and cloacal mechanisms, the morphology and physiological significance of lingual glands in wild American alligators remain poorly understood. This study examined lingual gland morphology and plasma …

Teaching Beyond The Textbook, Jada Fritzemeier

Celebrating Scholarship and Creativity Day (2018-)

As part of the Community Engaged Learning component in our Community Psychology class, we worked closely with St. Joseph Catholic School and Saint John’s Preparatory School to support students’ learning and understanding of their education and its values. Both schools have shared values and work to promote the integration of faith and the Benedictine values into their daily lives. While there, we provided one-on-one support to students with various academic and well-being needs as well as classroom assistance. These include after-school tutoring, mindfulness walks with students, interactive activities to promote community, and helping teachers and students in the classroom. By …

Post-Exercise Vitals Recovery Response In Barrel Horses: A Field Study On Cooling Methods Used By Competitors, Lauran E. Hetrick

Electronic Theses and Dissertations

Barrel racing demands peak physical performance from equine athletes, yet limited research evaluates the field-based strategies used to optimize equine recovery at competition. This study assessed recovery management approaches used by competitors to elucidate their influence of physiological recovery by measuring heart rate, respiratory rate, and body temperature during a high-profile barrel race competition. Physiological data were collected at baseline, immediately post-exercise, and during a 15–30-minute cooldown period to characterize recovery under real-world conditions. Significant increases in HR, RR, and BT occurred from baseline to post-run (p < 0.001), followed by reductions during cooldown (p < 0.01), though values remained elevated (p < 0.05). Rinsing reduced HR and RR (p < 0.01), while shade and fans decreased RR and variably influenced HR. Noise, as a confounding variable, decreased HR but increased BT (p < 0.001). Ultimately, these results emphasize multimodal recovery approaches in competitive equine management in the field.

Comparative Biomechanics: Blattodea Antennal Morphology And Physiology, Lucas W. Marsh

All Theses

Equipped with muscle-free antennae, many insects can twist and bend their antennae on demand. We hypothesized that hemolymph circulating through the antennae provides pressure that facilitates twisting and bending and provides a feedback control channel for tactile sensing in insects. To test this hypothesis, we conducted a thorough morphological and physiological analysis of antennae in three Clades of Blattodea. We studied morphology by evaluating the distinguishable features of the body and antenna, as well as the internal structure of the antennal lumen. Then, in a series of experiments on live cockroaches, we measured blood pressure along the antenna. This was …

Understanding The Role Of Toxs As A Bile Sensing Component Of The Toxrs Virulence Regulatory System In Vibrio Spp., Minje Kim

Dartmouth College Ph.D Dissertations

Pathogenic Vibrio bacteria, such as V. cholerae and V. parahaemolyticus, colonize in the human small intestine to cause severe gastrointestinal disease. During the infection, these bacteria encounter bile salts, antimicrobial cholesterol metabolites secreted into the intestine. Pathogenic Vibrio species have evolved to utilize bile salts as signals to regulate virulence. The signaling depends in part on ToxRS, a conserved co-component transmembrane transcription regulator. ToxRS consists of the transcription factor ToxR and its membrane-tethered binding partner ToxS. ToxS is required for ToxR stability and full transcriptional activity. Although bile salts are known to influence ToxRS-dependent virulence gene expression, the molecular …

Twenty-Four-Hour Intermittent Fasting Extends Lifespan At The Expense Of Fecundity In Daphnia, Meridith L. Smith

Undergraduate Honors Theses

Dietary restriction (DR) is a well-established intervention for extending lifespan, yet the specific efficacy of intermittent fasting (IF) and its associated trade-offs remain under-explored in many Daphnia magna. This study investigated the effects of three IF intervals—2h, 24h, and 48h—on the longevity and fecundity of two clones of Daphnia. We hypothesized that longer fasting intervals would significantly extend lifespan at the cost of reproductive output, consistent with the disposable soma theory of resource allocation.
Our results demonstrate that 24h IF significantly increased longevity relative to ad libitum controls, even outperforming caloric restriction (CR) by reducing late-life mortality. In …

Acute Effects Of Olympic Lifting Post-Activation Potentiation On Baseball Pitching Velocity And Ball Flight: A Crossover Study, Brent Hauser Pourciau

Doctoral Dissertations and Projects

This quantitative study evaluated the acute effect of an Olympic lifting-based post-activation potentiation (PAP) warm-up on fastball performance in collegiate baseball pitchers. Using a randomized, counterbalanced within-subjects crossover design (N = 13), each participant completed two warm-up conditions in a single indoor session: (a) a standard dynamic baseball warm-up and (b) the same standard warm-up followed by a brief Olympic-lifting PAP sequence (1 x 3 clean pulls at 80% predicted one-repetition maximum [1RM], 1 x 3 power cleans at 80% predicted 1RM, and 1 x 3 power jerks at 60% predicted 1RM, with 2-minute rests between sets) and a 3-minute …

Veratridine Suppresses Rictor-Mtorc2 Signaling Pathway In Colon Cancer Patient-Derived Xenograft Cells, Morgan Daniel Montgomery

Honors Thesis

Colorectal cancer (CRC) remains the second deadliest and fourth most common cancer in the world. The metastatic form of CRC is especially devastating due to a lack of effective and safer therapeutic options. Another challenge includes an increasing number of younger patients. Among critical signaling pathways overactivated in CRC, mTORC2 plays a key role in the progression of metastatic CRC, yet there is no selective mTORC2 inhibitor in the clinic. Interestingly, a natural plant alkaloid from the Veratrum genus, Veratridine (VTD), shows promise as VTD can upregulate UBXN2A, a colon-specific tumor suppressor protein. UBXN2A works with E3 ligases to ubiquitinate …

Evaluating Inner-Tainment With A Ghetto Perspective For Positive Thought Adjustment In Ghetto Communities, Shontae L. Graham

Doctoral Dissertations and Projects

Environmental challenges and disadvantages impact cognitive scripts and develop persistent frustration. Frustration is both mental and physical and can be negative or positive. It evokes emotion, which is prompted by memory and its associated level of importance. The integration of emotion, memory, and imagination can set the stage and create an act to transition negative frustration and align past experiences with new perspectives. This study used a qualitative Interpretive Phenomenological Analysis approach to investigate the use of self-scripted enactment as a self-help technique for positive thought adjustment. The technique is called Inner-tainment and was used to determine if there were …

Investigating How Caffeine Affects Perceived Exertion And To What Extent Young Adults Consumers Are Aware Of The Active Ingredients, Brianna Richter

Honors Projects

BACKGROUND: Caffeine is one of the most widely consumed substances in the world, often used to increase energy and alertness. From morning coffee to pre-workout and energy drinks, caffeine has become a daily staple for students, athletes, and working professionals. In recent years, caffeine consumption has increased significantly, with the energy drink and pre-workout industries rapidly expanding. Research has been conducted on the effects of caffeine; however, there is limited research examining how consumer awareness of caffeine products and their additional active ingredients influence perceived exertion and exercise in young adults. PURPOSE: This study investigated the perceived effect of …

Investigating The Synergistic Effects Of Mental And Physical Exhaustion On Learning And Attention In Emergency First Responders: An Eye-Tracking Study, Kayla Page

Electronic Theses and Dissertations

ABSTRACT

Exhaustion is known to impair cognitive functioning and performance, yet its effects on learning during video-based instruction among first responders and military service members remain underexplored. This study examined how mental, physical, and combined exhaustion independently influence learning outcomes and visual attention in a physically active sample drawn from military, public safety, and emergency service roles. Visual attention was measured utilizing eye tracking, focusing on fixation duration (FD) and fixation rate (FR). Participants completed instructional tasks under each exhaustion condition, allowing comparison of learning and gaze behavior across fatigue states. Results indicated that mental and physical exhaustion were associated …

Optimizing Itpa R178c Assays Via Hplc, Jared J. Reisnouer, Wally D. Pines

2026 Symposium

Two of the major nucleotide bases in DNA and RNA (Adenine and Guanine) are derived from the purine Inosine Monophosphate (IMP). IMP may occasionally form the noncanonical nucleotide Inosine Triphosphate (ITP) within the cell and become incorporated into DNA during replication, leading to potentially lethal errors. To combat this, human cells produce the “housekeeping” enzyme Inosine Triphosphatase (ITPA) to revert ITP to IMP. A mutation of this protein that replaces the 178th amino acid Arginine with Cysteine (R178C) is associated with a fatal infantile encephalopathy. Previous assessments of enzyme-substrate binding and catalysis for ITPA variants have been run at a …

Amyloid Beta-42 Neurotoxicity In Drosophila Retinal Development, Shay O. Sims, Pierce Duncan, Malachi Abon, Jacob G. Smith

Create@State

Alzheimer's disease (AD) represents one of the most prevalent neurodegenerative disorders globally. Thus far, the underlying mechanisms associated with the pathogenesis of AD are innately elusive. Two hallmarks associated with the progression of AD exist, including Amyloid-Beta 42 (Aβ42) protein plaque formation and hyperphosphorylation of tau proteins in neurons. Amyloid-beta is known to concentrate with other neuronal proteins as complexes form, including the cytoskeletal protein actin. However, whether actin contributes to neuronal decline in AD is unknown. To further understand the cellular cascades associated with AD, we investigated the role of cytoskeleton dynamics in modulating oxidative stress and neuroinflammation within …

Continuous Light And Pinealectomy: Two Models Of Melatonin Deficiency Revealing Distinct Interactions With Vitamin D Deficiency On Blood Parameters, Rebaz Sedeeq Shekh, Ismail Mustafa Maulood

Polytechnic Journal

Modern lifestyles reduce sunlight exposure and increase artificial light at night, potentially promoting vitamin D deficiency (VDD) and melatonin (MEL) suppression. The two hormones regulate immunity, erythropoiesis, and platelet (PLT) indices, but their combined hematological effects are not well characterized. We investigated the independent and combined effects of VDD and MEL deficiency on leukocyte profiles, erythrocyte indices, and PLT parameters in albino rats using two 12-week models (n = 8/group): continuous light (CL)-induced MEL suppression (Control, CL, VDD, and CL + VDD) and pinealectomy (Px)-induced MEL deficiency (Sham. Px, VDD, Px + VDD). Complete blood counts (CBCs) and inflammation-related ratios …

Hot Cities, Cool Lizards: Do College Campuses Create Urban Oases For Wildlife?, Ethan Heck, Javier Monzon Phd

Seaver College Research And Scholarly Achievement Symposium

Urban wildlife may experience stress due to the Urban Heat Island Effect. On the other hand, urban wildlife may experience relief, especially in arid ecosystems, due to the Urban Oasis Effect. The objective of this study was to test whether college campuses in southern California act as heat islands or oases for wildlife. We analyzed how temperature and water availability of microhabitats relate to the physiology of a widespread and common cold-blooded animal, the Western Fence Lizard (Sceloporus occidentalis). We logged environmental conditions in lizard hotspots at 11 university campuses across southern California and measured the hydration of lizards at …

Acute Nitrate Ingestion On Blood Pressure And Lower Body Power In Healthy Females, Sydney N. Brennan, Ryan Tran, Logan J. Dore, Henry C. Nafzger, Justin M. Foster, Kyle S. Geppert, Trevor J. Molnar, Renee M. Skiera, Rylee M. Perlmutter, Mikayla A. Yue, Michael Egiazarian, Christopher B. Sottile, Graciela K. Simpson, Layla A. Busquets, Abigial F. Ballhagen, Adam Pennell, Rachel Tan

Seaver College Research And Scholarly Achievement Symposium

Dietary nitrate supplementation can improve blood pressure and contractile function of type II (fast twitch) muscle fiber contraction and force production. However, limited data are available for  women and dosing guidelines for women. The purpose of this study is to investigate if nitrate ingestion, provided as nitrate-rich beetroot juice, improves blood pressure and countermovement jumps and cycling sprint performance compared to nitrate-depleted beetroot juice placebo in women. Eight recreationally active women have been assigned in a randomized, double-blind, crossover design to three experimental conditions to receive: (1) 2 x 70 ml of concentrated nitrate--depleted beetroot juice placebo (PL; 0.10 mmol …

Test-Retest Reliability Of Commercial Timing Gates (Dashr And Sport React) To Measure Neuromotor And Running Performance And Agility, Kyle S. Geppert, Renee M. Skiera, Caitlin O'Keeffe, Adam Pennell, Rachel Tan

Seaver College Research And Scholarly Achievement Symposium

Commercially-available laser-based timing gates are widely implemented for assessing neuromotor function, speed and agility; however, there is limited available data for the reliability and validity of this equipment. The purpose of this study is to establish the reliability and validity of timing gates from DASHR vs. Sport React compared to a manual stopwatch in a battery of neuromotor, performance and agility tests. Participants will complete 3 x 1-h visits over a 2- to 3-week period in a test-retest design. Participants will perform three rounds of the following tests, with 4-min rest separating each round: two reaction tests (Sport React Choice …

Oxygen Under Pressure: A Comparative Study Of Maximal Oxygen Uptake In Firefighters And Civilians, Jordan N. Hunt

Doctoral Dissertations and Projects

The purpose of this study aimed to investigate and compare V̇O2max levels between firefighters and age-matched individuals from the general population. This study used a quantitative, comparative, cross-sectional design to assess differences in directly measured V̇O2max with a breath-by-breath portable analyzer between firefighters and matched civilians, determine the percentage of firefighters meeting NFPA recommended fitness thresholds, and examine the accuracy of estimated V̇O2max values. A total sample size of 52 participants (26 per group) participated in this study. Firefighters exhibited significantly higher directly measured V̇O2max and V̇O2peak than age-, sex-, and BMI-matched individuals from the general population. Firefighters in this …