Physics Commons^™

First Measurement Of Hard Exclusive 𝛑⁻Δ⁺⁺ Electroproduction Beam-Spin Asymmetries Off The Proton, S. Diehl, N. Trotta, K. Joo, P. Achenbach, Z. Akbar, W. R. Armstrong, H. Atac, H. Avakian, L. Baashen, N. A. Baltzell, L. Barion, M. Bashkanov, M. Battaglieri, I. Bedlinskiy, F. Benmokhtar, A. Bianconi, A. S. Biselli, F. Bossù, K.-T. Brinkman, M. Zurek, Et Al., Clas Collaboration

Physics Faculty Publications

The polarized cross-section ratio σLT′/σ₀ from hard exclusive π⁻Δ⁺⁺ electroproduction off an unpolarized hydrogen target has been extracted based on beam-spin asymmetry measurements using a 10.2  GeV/10.6  GeV incident electron beam and the CLAS12 spectrometer at Jefferson Lab. The study, which provides the first observation of this channel in the deep-inelastic regime, focuses on very forward-pion kinematics in the valence regime, and photon virtualities ranging from 1.5  GeV² up to 7  GeV². The reaction provides a novel access to the d-quark content of the nucleon and to p→Δ⁺⁺ transition generalized parton …

Searching For Prompt And Long-Lived Dark Photons In Electroproduced E⁺ E⁻ Pairs With The Heavy Photon Search Experiment At Jlab, P. H. Adrian, N. A. Baltzell, M. Battaglieri, M. Bondí, S. Boyarinov, S. Bueltmann, P. Butti, V. D. Burkert, D. Calvo, T. Cao, M. Carpinelli, A. Celentano, G. Charles, L. Colaneri, W. Cooper, D. Crowe, C. Cuevas, A. D'Angelo, N. Dashyan, B. Wojtsekhowski, Et Al.

Physics Faculty Publications

The heavy photon search experiment (HPS) at the Thomas Jefferson National Accelerator Facility searches for electroproduced dark photons. We report results from the 2016 engineering run consisting of 10 608  nb⁻¹ of data for both the prompt and displaced vertex searches. A search for a prompt resonance in the e⁺e⁻ invariant mass distribution between 39 and 179 MeV showed no evidence of dark photons above the large QED background, limiting the coupling of ε²≳10⁻⁵, in agreement with previous searches. The search for displaced vertices showed no evidence of excess signal over background …

Understanding The Field And Frequency Dependence Of Rf Loss In Srf Cavities, Pashupati Dhakal, G. Ciovati, Alex V. Gurevich, Bashu D. Khanal

Physics Faculty Publications

SRF cavities subjected to heat treatment below 200 °C in the presence of nitrogen showed an improvement in quality factor while maintaining an accelerating gradient above 25 MV/m. Here, we report the rf performance of several single-cell superconducting radio frequency cavities with frequency ranging from 0.75 - 3.0 GHz subjected to low temperature heat treatment in nitrogen environment. The cavities were treated at temperature 120 - 175 oC for 24 - 48 hours in low partial pressure of ultra-pure nitrogen gas. The improvement in Q₀ with Q-rise was observed when nitrogen gas was injected ~300 °C during the furnace treatment. …

Analytic Continuation Of The Relativistic Three-Particle Scattering Amplitudes, Sebastian M. Dawid, Md Habib E. Islam, Raúl A. Briceño

Physics Faculty Publications

We investigate the relativistic scattering of three identical scalar bosons interacting via pair-wise interactions. Extending techniques from the nonrelativistic three-body scattering theory, we provide a detailed and general prescription for solving and analytically continuing integral equations describing the three-body reactions. We use these techniques to study a system with zero angular momenta described by a single scattering length leading to a bound state in a two-body subchannel. We obtain bound-state-particle and three-particle amplitudes in the previously unexplored kinematical regime; in particular, for real energies below elastic thresholds and complex energies in the physical and unphysical Riemann sheets. We extract positions …

Electron Scattering And Neutrino Physics, A. M. Ankowski, A. Ashkenazi, S. Bacca, J. L. Barrow, M. Betancourt, A. Bodek, M. E. Christy, L. Doria, S. Dytman, A. Friedland, O. Hen, C. J. Horowitz, N. Jachowicz, W. Ketchum, T. Lux, K. Mahn, C. Mariani, J. Newby, V. Pandey, A. Papadopoulou, E. Radicioni, F. Sánchez, C. Sfienti, J. M. Udías, L. Weinstein, L. Alvarez-Ruso, J. E. Amaro, C. A. Argüelles, A. B. Balantekin, S. Bolognesi, V. Brdar, P. Butti, S. Carey, Z. Djurcic, O. Dvornikov, S. Edayath, S. Gardiner, J. Isaacson, W. Jay, K. S. Mcfarland, A. Nikolakopoulos, A. Norrick, S. Pastore, G. Paz, M. H. Reno, I. Ruiz Simo, J. E. Sobczyk, A. Sousa, N. Toro, Y. D. Tsai, M. Wagman, J. G. Walsh, G. Yang

Physics Faculty Publications

A thorough understanding of neutrino–nucleus scattering physics is crucial for the successful execution of the entire US neutrino physics program. Neutrino–nucleus interaction constitutes one of the biggest systematic uncertainties in neutrino experiments—both at intermediate energies affecting long-baseline deep underground neutrino experiment, as well as at low energies affecting coherent scattering neutrino program—and could well be the difference between achieving or missing discovery level precision. To this end, electron–nucleus scattering experiments provide vital information to test, assess and validate different nuclear models and event generators intended to test, assess and validate different nuclear models and event generators intended to be used …

Measurement Of The Helicity Asymmetry E For The 𝛾p → P𝛑⁰ Reaction In The Resonance Region, C. W. Kim, N. Zachariou, M. Bashkanov, W. J. Briscoe, S. Fegan, V. L. Kashevarov, K. Nikonov, A. Sarantsev, A. Schmidt, I. I. Strakovsky, D. P. Watts, R. L. Workman, P. Achenbach, Z. Akbar, M. J. Amaryan, G. Angelini, W. R. Armstrong, H. Atac, L. Baashen, M. Zurek, Et Al., The Clas Collaboration

Physics Faculty Publications

The double-spin-polarization observable E for 𝛾^→ p^→ → p𝛑⁰ has been measured with the CEBAF Large Acceptance Spectrometer (CLAS) at photon beam energies E𝛾 from 0.367 to 2.173 GeV (corresponding to center-of-mass energies from 1.240 to 2.200 GeV) for pion center-of-mass angles, cos θ^c.m._𝛑⁰, between - 0.86 and 0.82. These new CLAS measurements cover a broader energy range and have smaller uncertainties compared to previous CBELSA data and provide an important independent check on systematics. These measurements are compared to predictions as well as new global fits from The George Washington University, Mainz, and Bonn-Gatchina …

Crab Cavities For Ilc, P. A. Mcintosh, S. A. Belomestnykh, G. Burt, R. Calaga, S. U. De Silva, J. R. Delayen, I. V. Gonin, T. N. Khabiboulline, A. Lunin, T. Okugi, Y. M. Orlov, S. Verdú-Andrés, B. P. Xiao, V. P. Yakovlev, A. Yamamoto

Physics Faculty Publications

For the 14 mrad crossing angle proposed, crab cavity systems are fundamentally anticipated for the viable operation of the International Linear Collider (ILC), in order to maximise its luminosity performance. Since 2021, a specialist development team have been defining optimum crab cavity technologies which can fulfil the operational requirements for ILC, both for its baseline centre-of-mass energy of 250 GeV, but also extending those requirements out to higher beam collision intensities. Five design teams have established crab cavity technology solutions, which have the capability to also operate up to 1 TeV centre-of-mass. This presentation showcases the key performance capabilities of …

Quantum Computations Of The O(3) Model Using Qumodes, R. Jha, Felix Ringer, G. Siopsis, Shane Thompson

Physics Faculty Publications

We express the discrete 1+1-dimensional O(3) non-linear sigma model (NLσM) in a form well-suited for the continuous variable approach to quantum computing. Within the Schwinger boson formulation, we need two qumodes (quantum-mechanical oscillators) at each lattice site. We envision that it might be possible to reach the scaling regime of this model and observe asymptotic freedom on near-term photonic quantum devices in the coming decade.

Status And Future Plans For C³ R&D, Emilio A. Nanni, Martin Breidenbach, Zenghai Li, Caterina Vernieri, Faya Wang, Glen White, Mei Bai, Sergey Belomestnykh, Pushpalatha Bhat, Tim Barklow, William J. Berg, Valery Borzenets, John Byrd, Ankur Dhar, Ram C. Dhuley, Chris Doss, Joseph Duris, Auralee Edelen, Claudio Emma, Joseph Frisch, Annika Gabriel, Spenser Gessner, Carsten Hast, Chunguang Jing, Arkadiy Klebaner, Dongsung Kim, Anatoly Krasnykh, John Lewellen, Matthias Liepe, Michael Litos, Xueying Lu, Jared Maxon, David Montanari, Pietro Musumeci, Sergei Nagaitsev, Alireza Nassiri, Cho-Kuen Ng, David A. K. Othman, Marco Oriunno, Dennis Palmer, J. Ritchie Patterson, Michael E. Peskin, Thomas J. Peterson, John Power, Ji Qiang, James Rosenzweig, Vladimir Shiltsev, Muhammad Shumail, Evgenya Simakov, Emma Snively, Bruno Spataro, Sami Tantawi, Harry Van Der Graaf, Brandon Weatherford, Juhao Wu, Kent P. Wootton

Physics Faculty Publications

C³ is an opportunity to realize an e⁺e^- collider for the study of the Higgs boson at √s = 250 GeV, with a well defined upgrade path to 550 GeV while staying on the same short facility footprint [2,3]. C³ is based on a fundamentally new approach to normal conducting linear accelerators that achieves both high gradient and high efficiency at relatively low cost. Given the advanced state of linear collider designs, the key system that requires technical maturation for C³ is the main linac. This paper presents the staged approach towards a …

Nuclear Magnetic Quadrupole Moment Of ¹⁷⁵Lu And Parity-Violating Polarization Degree Of Levels In ¹⁷⁵Luoh⁺, Igor Kurchavov, Daniel Maison, Leonid Skripnikov, Matt Grau, Alexander Petrov

Physics Faculty Publications

A calculation is performed of the parity-violating polarizations in the external electric field, which are associated with the electron electric dipole moment (eEDM) and magnetic quadrupole moment (MQM) of the ¹⁷⁵Lu nucleus, as well as the determination of the rovibrational structure for the ¹⁷⁵LuOH⁺ cation. Beyond the bending of the molecule, the slight effect of the stretching of the distance between Lu and OH is taken into account. This study is required for the preparation of the experiment and for the extraction of the eEDM and MQM values of ¹⁷⁵Lu from future measurements.

Machine-Assisted Discovery Of Integrable Symplectic Mappings, T. Zolkin, Y. Kharkov, S. Nagaitsev

Physics Faculty Publications

We present a new automated method for finding integrable symplectic maps of the plane. These dynamical systems possess a hidden symmetry associated with an existence of conserved quantities, i.e., integrals of motion. The core idea of the algorithm is based on the knowledge that the evolution of an integrable system in the phase space is restricted to a lower-dimensional submanifold. Limiting ourselves to polygon invariants of motion, we analyze the shape of individual trajectories thus successfully distinguishing integrable motion from chaotic cases. For example, our method rediscovers some of the famous McMillan-Suris integrable mappings and ultradiscrete Painlevé equations. In total, …

Numerical Simulations Of Radiation Reaction Using Lorentz-Abraham-Dirac Formalism, E. Rogers, B. Terzic, E. Breen, E. Johnson, G. Krafft

Physics Faculty Publications

An accelerating charged particle emits electromagnetic radiation. The motion of the particle is further damped via self-interaction with its own radiation. For relativistic particles, the subsequent motion is described via a correction to the Lorentz force, known as the Lorentz-Abraham-Dirac force. The aim of this research is to use the Lorentz-Abraham-Dirac force to computationally simulate the radiation damping that occurs during nonlinear inverse Compton scattering. We build on our previous work and the code which simulates single-emission inverse Compton scattering to incorporate the effect of multiple emissions, thereby modeling the radiation reaction.

Light Water Sustainability Program: Optimizing Information Automation Using A New Method Based On System-Theoretic Process Analysis, Jeffrey Joe, Larry Hettinger, Marvin Dainoff, Patrick Murray, Yusuke Yamani

Psychology Faculty Publications

This report describes the interim progress for research supporting the design and optimization of information automation systems for nuclear power plants. Much of the domestic nuclear fleet is currently focused on modernizing technologies and processes, including transitioning toward digitalization in the control room and elsewhere throughout the plant, along with a greater use of automation, artificial intelligence, robotics, and other emerging technologies. While there are significant opportunities to apply these technologies toward greater plant safety, efficiency, and overall cost-effectiveness, optimizing their design and avoiding potential safety and performance risks depends on ensuring that human-performance-related organizational and technical design issues are …

High Energy Blue Light Induces Oxidative Stress And Retinal Cell Apoptosis, Jessica Malinsky

Capstone Showcase

Blue light (BL) is a high energy, short wavelength spanning 400 to 500 nm. Found in technological and environmental forms, BL has been shown to induce photochemical damage of the retina by reactive oxygen species (ROS) production. Excess ROS leads to oxidative stress, which disrupts retinal mitochondrial structure and function. As mitochondria amply occupy photoreceptors, they also contribute to oxidative stress due to their selectively significant absorption of BL at 400 to 500 nm. ROS generation that induces oxidative stress subsequently promotes retinal mitochondrial apoptosis. BL filtering and preventative mechanisms have been suggested to improve or repair BL-induced retinal damage, …

Optical Tweezers: Exerting Force With Light, Gabriella Seifert

Scripps Senior Theses

Photons carry momentum. When a tightly-focused beam of photons hit a particle, they transfer some of their momentum to the particle, exerting a force. Optical tweezers take advantage of this phenomenon to trap (or “tweeze”) a spherical bead just after the focus of a diverging laser beam, creating a potential well that pulls in beads. In this thesis, I predict the force exerted on trapped beads and measure the actual force using an optical tweezers setup that I built. To predict the force, I follow the path of all possible rays from a diverging beam incident on a spherical bead …

Effect Of Decorating Super Paramagnetic Iron Oxide Nanoparticles With Silver Nanoparticles On Their Magneto-Photo Thermal Heating Efficiency, Anthony Joseph Afful

All Graduate Theses, Dissertations, and Other Capstone Projects

Cancer treatment is rather dangerous to the body, often involving many secondary effects, including nausea, hair loss, and weight fluctuations. The search for non-invasive, highly efficient, and targetable treatments ameliorates these issues. Super paramagnetic iron oxide nanoparticles (SPIONS) have been used for other medical purposes such as magnetic resonance imaging contrast agent and is being extensively studied as a potential candidate for many cancer therapeutic and diagnostic approaches due to its biocompatibility and superior magnetic properties. When subjected to an external alternating magnetic field SPIONS generate heat mainly due to the friction of the SPIONS against the fluid it is …

Color-Changing Reflection Hologram For Quality Assurance Of Therapeutic Ultrasound Systems, Tatsiana Mikulchyk, John Walsh, Jacinta Browne, Izabela Naydenova, Dervil Cody

Articles

The acoustic output of clinical therapeutic ultrasound equipment requires regular quality assurance (QA) testing to ensure the safety and efficacy of the treatment and that any potentially harmful deviations from the expected output power density are detected as soon as possible. A hologram, consisting of a reflection grating fabricated in an acrylate photopolymer film, has been developed to produce an immediate, visible, and permanent change in the color of the reconstructed hologram from red to green in response to incident ultrasound energy. The influence of the therapeutic ultrasound insonation parameters (exposure time, ultrasound power density, and proximity to the point …

Long-Range Aceo Phenomena In Microfluidic Channel, Diganta Dutta, Keifer Smith, Xavier Palmer

Electrical & Computer Engineering Faculty Publications

Microfluidic devices are increasingly utilized in numerous industries, including that of medicine, for their abilities to pump and mix fluid at a microscale. Within these devices, microchannels paired with microelectrodes enable the mixing and transportation of ionized fluid. The ionization process charges the microchannel and manipulates the fluid with an electric field. Although complex in operation at the microscale, microchannels within microfluidic devices are easy to produce and economical. This paper uses simulations to convey helpful insights into the analysis of electrokinetic microfluidic device phenomena. The simulations in this paper use the Navier–Stokes and Poisson Nernst–Planck equations solved using COMSOL …

High Figure Of Merit Spin Polarized Electron Sources Grown Via Mocvd, Benjamin Belfore, Adam Masters, Deewakar Poudel, Greg Blume, Stephen Polly, Erdong Wang, Seth M. Hubbard, Marcy Stutzman, Joseph M. Grames, Matt Poelker, Matt Grau, Sylvain Marsillac

Electrical & Computer Engineering Faculty Publications

Spin polarized photocathodes are key to the future operation of electron accelerators such as the ones at Thomas Jefferson National Accelerator Facility and Brookhaven National Laboratory. Currently, these photocathodes come in short supply due to limited production by molecular beam epitaxy. By developing a process to implement similar structures using metal organic chemical vapor deposition, the availability of these devices can be increased. In this paper, we detail the implementation of recent photocathode advancements via metal organic chemical vapor deposition process and show an improvement in both polarization and quantum efficiency of our devices compared to those fabricated via molecular …

Quantum Efficiency Enhancement In Simulated Nanostructured Negative Electron Affinity Gaas Photocathodes, Md Aziz Ar Rahman, Shukui Zhang, Hani E. Elsayed-Ali

Physics Faculty Publications

Nanostructured negative electron affinity GaAs photocathodes for a polarized electron source are studied using finite difference time domain optical simulation. The structures studied are nanosquare columns, truncated nanocones, and truncated nanopyramids. Mie-type resonances in the 700–800 nm waveband, suitable for generation of polarized electrons, are identified. At resonance wavelengths, the nanostructures can absorb up to 99% of the incident light. For nanosquare columns and truncated nanocones, the maximum quantum efficiency (QE) at 780 nm obtained from simulation is 27%, whereas for simulated nanopyramids, the QE is ∼21%. The high photocathode quantum efficiency is due to the shift of Mie resonance …

On The Chronological Understanding Of The Homogeneous Dielectric Barrier Discharge, Xinpei Lu, Zhi Fang, Dong Dai, Tao Shao, Feng Liu, Cheng Zhang, Dawei Liu, Lanlan Nie, Chunqi Jiang

Bioelectrics Publications

Dielectric barrier discharges (DBD) are widely utilised non-equilibrium atmospheric pressure plasmas with a diverse range of applications, such as material processing, surface treatment, light sources, pollution control, and medicine. Over the course of several decades, extensive research has been dedicated to the generation of homogeneous DBD (H-DBD), focussing on understanding the transition from H-DBD to filamentary DBD and exploring strategies to create and sustain H-DBD. This paper first discusses the influence of various parameters on DBD, including gas flow, dielectric material, surface conductivity, and mesh electrode. Secondly, a chronological literature review is presented, highlighting the development of H-DBD and the …

The Future Between Quantum Computing And Cybersecurity, Daniel Dorazio

Williams Honors College, Honors Research Projects

Quantum computing, a novel branch of technology based on quantum theory, processes information in ways beyond the capabilities of classical computers. Traditional computers use binary digits [bits], but quantum computers use quantum binary digits [qubits] that can exist in multiple states simultaneously. Since developing the first two-qubit quantum computer in 1998, the quantum computing field has experienced rapid growth.

Cryptographic algorithms such as RSA and ECC, essential for internet security, rely on the difficulty of complex math problems that classical computers can’t solve. However, the advancement of quantum technology threatens these encryption systems. Algorithms, such as Shor’s, leverage the power …

Detailed Analysis Of The Tev Γ-Ray Sources 3hwc J1928+178, 3hwc J1930+188, And The New Source Hawc J1932+192, A. Albert, R. Alfaro, C. Alvarez, J. C. Arteaga-Velázquez, D. Avila Rojas, H. A.Ayala Solares, R. Babu, E. Belmont-Moreno, C. Brisbois, K. S. Caballero-Mora, T. Capistrán, A. Carramiñana, S. Casanova, O. Chaparro-Amaro, U. Cotti, J. Cotzomi, S. Coutiño De León, E. De La Fuente, C. De Leon, R. Diaz Hernandez, J. C. Diaz-Velez, B. L. Dingus, M. A. Duvernois, M. Durocher, K. Engel, C. Espinoza, K. L. Fan, M. Fernandez Alonso, N. Fraija, J. A. Garcia-Gonzalez, F. Garfias, H. Goksu, M. M. Gonzalez, J. A. Goodman, J. P. Harding, S. Hernandez, J. Hinton, B. Hona, D. Huang, F. Hueyotl-Zahuantitla, P. Huntemeyer, A. Iriarte, A. Jardin-Blicq, V. Joshi, S. Kaufmann, D. Kieda, W. H. Lee, H. Leon Vargas, J. T. Linnemann, A. L. Longinotti, G. Luis-Raya, R. Lopez-Coto, K. Malone, V. Marandon, O. Martinez, J. Martinez-Castro, J. A. Matthews, P. Miranda-Romagnoli, J. A. Moralez-Soto, E. Moreno, M. Mostafa, A. Nayerhoda, L. Nellen, M. Newbold, M. U. Nisa, R. Noriega-Papaqui, L. Olivera-Nieto, N. Omodei, A. Peisker, Y. Perez Araujo, E. G. Perez-Perez, C. D. Rho, D. Rosa-Gonzalez, E. Ruiz-Velasco, H. Salazar, D. Salazar-Gallegos, F. Salesa Greus, A. Sandoval, M. Schneider, J. Serna-Franco, A. J. Smith, Y. Son, R. W. Springer, O. Tibolla, K. Tollefson, I. Torres, R. Torres-Escobedo, R. Turner, F. Urena-Mena, L. Villasenor, Xiaojie Wang, F. Werner, E. Willox, H. Zhou

Physics Faculty Research & Creative Works

The latest High Altitude Water Cherenkov (HAWC) point-like source catalog up to 56 TeV reported the detection of two sources in the region of the Galactic plane at galactic longitude 52° < ℓ < 55°, 3HWC J1930+188 and 3HWC J1928+178. The first one is associated with a known TeV source, the supernova remnant SNR G054.1+00.3. It was discovered by one of the currently operating Imaging Atmospheric Cherenkov Telescope (IACT), the Very Energetic Radiation Imaging Telescope Array System (VERITAS), detected by the High Energy Stereoscopic System (H.E.S.S), and identified as a composite SNR. However, the source 3HWC J1928+178, discovered by HAWC and coincident with the pulsar PSR J1928+1746, was not detected by any IACT despite their long exposure on the region, until a recent new analysis of H.E.S.S. data was able to confirm it. Moreover, no X-ray counterpart has been detected from this pulsar. We present a multicomponent fit of this region using the latest HAWC data. This reveals an additional new source, HAWC J1932+192, which is potentially associated with the pulsar PSR J1932+1916, whose γ-ray emission could come from the acceleration of particles in its pulsar wind nebula. In the case of 3HWC J1928+178, several possible explanations are explored, in an attempt to unveil the origins of the very-high-energy γ-ray emission.

Recent Advances In Experimental Design And Data Analysis To Characterize Prokaryotic Motility, Megan M. Dubay, Jacqueline Acres, Max Riekeles, Jay Nadeau

Physics Faculty Publications and Presentations

Bacterial motility plays a key role in important cell processes such as chemotaxis and biofilm formation, but is challenging to quantify due to the small size of the individual microorganisms and the complex interplay of biological and physical factors that influence motility phenotypes. Swimming, the first type of motility described in bacteria, still remains largely unquantified. Light microscopy has enabled qualitative characterization of swimming patterns seen in different strains, such as run and tumble, run-reverse-flick, run and slow, stop and coil, and push and pull, which has allowed for elucidation of the underlying physics. However, quantifying these behaviors (e.g., identifying …

Electromagnetic Radiation From A Spherical Static Current Source Coupled To Harmonic Axion Field, Railing Chang, Huai-Yi Xie, P. T. Leung

Physics Faculty Publications and Presentations

The electromagnetic fields generated from a static current source on a spherical surface are calculated in the framework of axion electrodynamics to first order in the coupling parameter. Comparisons of the results are made with reference to various results obtained in conventional Maxwell electrodynamics, as well as previous results obtained for point magnetic dipole source coupled to harmonic axion fields. Distinct features from the results so obtained are highlighted for possible experimental probing of the axions via electromagnetic interactions. In particular, electromagnetic radiation from sources with strong magnetic field is studied which may enable the detection of a cosmic …

Speeding The Generation Of Giant Entangled States Using Low-Frequency Modulations, Abdelaziz Benseghir, Azeddine Messikh, Ahmed Bouketir

Turkish Journal of Physics

In this paper, we generalize the shortcuts to adiabacity for the quantum Rabi model by simultaneously modulating its two components, namely, the two-level system and the cavity mode. This will eliminate the counterrotating terms which in turn helps to simulate the Rabi model by the Jaynes-Cummings model without requiring a largely detuned light-matter coupling. We focus on the low-frequency modulations since it is easy to realize them experimentally. The results show that these modulations can significantly shorten the evaluation time, generate much larger entanglement cat states, and robust against imperfection of time evaluation and dissipation.

Polycomb Deficiency Drives A Foxp2-High Aggressive State Targetable By Epigenetic Inhibitors, Fan Chen, Aria Byrd, Jinpeng Liu, Robert M. Flight, Tanner Ducote, Kassandra J. Naughton, Xiulong Song, Abigail R Edgin, Alexsandr Lukyanchuk, Danielle T. Dixon, Christian M. Gosser, Dave-Preston Esoe, Rani Jayswal, Stuart H. Orkin, Hunter N. B. Moseley, Chi Wang, Christine Fillmore Brainson

Markey Cancer Center Faculty Publications

Inhibitors of the Polycomb Repressive Complex 2 (PRC2) histone methyltransferase EZH2 are approved for certain cancers, but realizing their wider utility relies upon understanding PRC2 biology in each cancer system. Using a genetic model to delete Ezh2 in KRAS-driven lung adenocarcinomas, we observed that Ezh2 haplo-insufficient tumors were less lethal and lower grade than Ezh2 fully-insufficient tumors, which were poorly differentiated and metastatic. Using three-dimensional cultures and in vivo experiments, we determined that EZH2-deficient tumors were vulnerable to H3K27 demethylase or BET inhibitors. PRC2 loss/inhibition led to de-repression of FOXP2, a transcription factor that promotes migration and stemness, and FOXP2 …

Phys 275: Intro To Scientific Computing, David Goldberg

Open Educational Resources

No abstract provided.

Innovations In Drop Shape Analysis Using Deep Learning And Solving The Young-Laplace Equation For An Axisymmetric Pendant Drop, Andres P. Hyer

Theses and Dissertations

Axisymmetric Drop Shape Analysis (ADSA) is a technique commonly used to determine surface or interfacial tension. Applications of traditional ASDA methods to process analytical technologies are limited by computational speed and image quality. Here, we address these limitations using a novel machine learning approach to analysis. With a convolutional neural network (CNN), we were able to achieve an experimental fit precision of (+/-) 0.122 mN/m in predicting the surface tension of drop images at a rate of 1.5 ms^-1 versus 7.7 s^-1, which is more than 5,000 times faster than the traditional method. The results are validated on real images …

Mechanisms Of Emulsion Destabilization: An Investigation Of Surfactant, Stabilizer, And Detergent Based Formulations Using Diffusing Wave Spectroscopy, Jordan N. Nowaczyk

Theses and Dissertations

Conventional approaches for studying emulsions, such as microscopy and macroscopic phase tracking, present challenges when it comes to establishing detailed mechanistic descriptions of the impact of emulsifier and stabilizer additives. Additionally, while a combination of sizing methods and macroscopic phase tracking can provide insights into droplet size changes and concentration, the use of multiple measurements can be cumbersome and error-prone. It is the focus of this work, to present a new method for studying water in oil (W/O) emulsions that involves using diffusing wave spectroscopy (DWS) to examine the impact of three different surface stabilizing additives at varying concentrations. By …