Physics Commons^™

Modeling Kinetics Of 5-Aminolevulinic Acid-Induced Protoporphyrin Ix Accumulation For Optimal Photodynamic Therapy, Priscilla Melebor

Graduate Masters Theses

Photodynamic therapy (PDT) is a minimally invasive treatment that uses light-activated photosensitizers to selectively destroy diseased tissue through the generation of reactive oxygen species. However, conventional in vitro models often fail to accurately reproduce the pharmacokinetics of photosensitizer accumulation and clearance observed in vivo. This study investigated protoporphyrin IX (PpIX) accumulation following 5-aminolevulinic acid (ALA) exposure under physiologically relevant conditions using two-dimensional (2D) monolayers and three-dimensional (3D) spheroids. By comparing continuous ALA exposure with transient exposure followed by ALA washout, this work provides a more biologically relevant framework for studying PpIX kinetics and optimizing photodynamic therapy.

Demonstrating Superresolution In Radar Range Estimation Using A Denoising Autoencoder, Robert Czupryniak, Abhishek Chakraborty, Andrew N. Jordan, John C. Howell

Mathematics, Physics, and Computer Science Faculty Articles and Research

We apply machine learning methods to demonstrate radar range superresolution using a denoising autoencoder trained without supervision. Focusing on the estimation of a single physical parameter, the separation between two scatterers in the subwavelength regime, we constrain the network to a one-dimensional bottleneck layer with its size matched to the parameter dimensionality. We find that the bottleneck layer forms a reproducible, monotonic mapping with the true separation, showing that the network learns a low-dimensional representation directly aligned with the underlying physical parameter. We further show that this representation preserves the Fisher information of the signal, indicating that the network recovers …

Rockin’ Rover On The Rainbow Road, Michael Kolta, Lawrence Burgee, Ying Yuan

Transformations

This paper presents a progressive series of age-appropriate lesson plans for grades K-12 that all use the same interdisciplinary activity to educate students about Science, Technology, Engineering, Art, and Mathematics (STEAM) simultaneously. Technology from Texas Instruments (TI) was employed including a TI Nspire graphing calculator that can run Python programs, a TI Innovator Hub, and a TI Rover. The TI Rover is a small, robotic car that has sensors and is controlled by the calculator via the Hub hardware interface. A Python program was developed that uses the color sensor in the Rover to detect the color on colored paper …

Measuring Cosmic Expansion From Early To Late Times Using Quasars, Galaxies, & Local Supernovae, Rajeev Vaisakh

Physics Theses and Dissertations

This dissertation investigates the evolution of cosmic expansion across a wide redshift ($z$) range by combining measurements from quasars \& galaxies in the distant universe $(z > 0.8)$ with those obtained from stripped-core collapse supernovae observations from the nearby universe $(z < 0.1)$. Using the DESI spectroscopic survey, we analyze large-scale clustering from quasars over $0.8 < z < 2.1$ and emission line galaxies over $0.8 < z < 1.6$, contributing to DESI DR2 BAO and full-shape measurements of cosmic expansion and structure growth. Combined with BBN in flat $\Lambda$CDM, DESI DR2 BAO gives $H_0 = 68.51 \pm 0.58$ km s$^{-1}$ Mpc$^{-1}$, while combinations of DESI BAO with CMB and supernova data show a preference for evolving dark energy, with representative constraints such as $w_0 = -0.752 \pm 0.057$ and $w_a = -0.86^{+0.23}_{-0.20}$ for DESI+CMB+DESY5. Using the ROTSE-III Supernova Survey and the expanding photosphere method (EPM), we measure distances to a sample of six supernovae for which the thermal phase can be clearly identified. This analysis focuses on testing whether reliable EPM distances can be obtained for this population. The resulting distances will eventually be compared with independent estimates from the literature. Establishing consistency with these external measurements represents an important step toward applying this methodology to larger samples, with the eventual goal of using ROTSE supernova distances to provide an independent measurement of the local Hubble constant.

Ai-Driven Segmentation And Volumetric Response Modeling Of Liver Regions To Radiotherapy, Aashish Chandra Gupta

Dissertations and Theses (Open Access)

In liver-directed radiotherapy (RT), liver regions receiving higher doses typically undergo atrophy while contralateral/adjacent lower-dose regions may exhibit compensatory hypertrophy through regeneration of healthy tissue. Optimizing the RT plan to promote regional hypertrophy while minimizing the risk of developing atrophy has the potential to enhance post-RT liver function and long-term survivorship. However, current clinical practice largely relies on global liver dose-volume metrics during RT-planning, which may obscure favorable dose-response correlation and limit actionable guidance for clinicians. Therefore, we hypothesized that post-RT regional liver response is governed by a combination of region-specific dose-volume and patient clinical features, and that these responses …

Phase-Resolved Measurement And Arbitrary Mode Conversion Of Structured Light, Somayeh Ghazanfarpour

Electronic Theses and Dissertations

This dissertation presents a single-shot phase and amplitude retrieval technique based on spatial light modulator (SLM)-based digital holography. The proposed method enables accurate reconstruction of complex optical fields from a single interferogram, reducing sensitivity to environmental fluctuations and improving experimental stability compared to conventional multi-shot approaches. In addition, a programmable arbitrary mode converter is developed using SLM-based wavefront shaping. By introducing controlled astigmatism and engineering the differential Gouy phase between orthogonal components, the system enables flexible transformation between structured light modes, including Hermite–Gaussian and Laguerre–Gaussian beams. Numerical results demonstrate reliable phase recovery and efficient mode conversion, validating the performance of …

Electrical Resistivity Tomography Investigation Of Hard Rock Aquifers In The Salinian Block, Roxanne C. Chambers

Physics

Identifying a productive groundwater source in hard rock terrain is often a challenge. Conventional hard rock aquifer models commonly describe a weathering derived layered system consisting of a laminated layer, an underlying fractured zone, and a competent granitic basement. This study investigates the applicability of this conceptual model at Lockshaw Ranch, a granitic site within the Salinian Block of central California located near the Rinconada Fault.

Previous electrical resistivity tomography (ERT) surveys and time domain electromagnetic (TDEM) data were integrated with a newly acquired ERT profile (ERT-06) are used to characterize the subsurface structure and identify potential groundwater bearing zones. …

Experimental Methods For Cryogenic Rare Event Detection: Cuore And Cupid, Alessandro Libenson

Physics

This senior project was written with the primary purpose of serving as a introductory guide for undergraduate students learning about the experimental methods used in the CUORE and CUPID Collaborations. In particular, this project is geared towards getting students in Dr. Gutierrez's research group at Cal Poly up to speed on what CUORE and CUPID actually do. I wrote this as an undergraduate aiming to help future undergraduates. For Cal Poly students, I would suggest the following prerequisites before reading this paper: Electronics and Instrumentation, Quantum Laboratory 1, and the equivalent of the coding/analysis class. It is also important to …

Commissioning And Validation Of An Electron Treatment Planning System: Following Mppg.5.B Guidelines, Hailey N. Reaux

LSU Master's Theses

Purpose: The purpose of this work was to commission and validate the electron treatment planning system ElectronRT (eRT) (.decimal, Sanford, FL) for clinical use following the recommendations outlined in the American Association of Physicists in Medicine (AAPM) Medical Physics Practice Guideline (MPPG) 5.b (2022). The system’s ability to accurately calculate electron dose distributions was evaluated under normal and oblique beam incidence, varying field sizes and source-to-surface distances (SSDs), and irregular surface geometries.

Methods: The eRT beam model was configured using commissioning data from an Elekta Infinity linear accelerator at Mary Bird Perkins Cancer Center (MBPCC). Validation measurements were performed for …

The Yorp Effect In Reboundx, Kaelyn Clement

UNLV Theses, Dissertations, Professional Papers, and Capstones

The Yarkovsky-O’Keefe-Radzievskii-Paddack (YORP) effect is a radiation-induced torque that can affect the spin and rotational obliquity of small bodies. It has been observed to alter the rotation rate of asteroids in the Solar System (Lowry et al. 2007; Taylor et al. 2007). Under extreme circumstances, YORP can cause a body to fragment, inducing a cascade of fissions. This effect may be important in driving the pollution of white dwarf atmospheres in conjunction with other radiative forces. I developed a YORP calculator for REBOUNDX (Tamayo et al. 2020), an extensional library to the N-body integrator REBOUND (Rein & Liu 2012). I …

Modeling Velocity Distributions Of Interstellar Neutral Hydrogen In The Heliosphere, Lucas Robert Dyke

Dartmouth College Ph.D Dissertations

As interstellar neutral hydrogen (ISN H) is the most abundant neutral element in the helio- sphere, the region within which the solar wind interacts with the portion of the interstellar medium through which our solar system moves through, it is integral that we aim to under- stand its many properties and interactions within this region. This work details the synthesis and use of a model of ISN H, using trajectory methods to backtrace from a target point at a radial distance of 1 au where explorer probes like Interstellar Boundary Explorer (IBEX) and Interstellar Mapping and Acceleration Probe (IMAP) reside. …

Search For Slow-Moving Magnetic Monopoles With An Improved High-Energy Event Removal Algorithm, Reeshi N. Gihosal

Honors Theses

Fermilab’s NOvA (NuMI Off-axis 𝑣𝑒 Appearance) experiment focuses on understanding the behavior of neutrinos and how they affect the cosmos. A sub-focus of the NOvA experiment is the search for magnetic monopoles. These elusive particles have not yet been observed in nature, leaving their behavior to be mysterious. The Far Detector, located in Ash River, MN, is integral in the search for these particles. This project is on simulated magnetic monopoles with speeds thousandths the speed of light, with focus on the role of slicing algorithms in event reconstruction using the NOvA experiment’s reconstruction algorithm. Using sample data, analysis occurred …

Between Chronicle And Legend: A Two-Scene Environment And Visual Effects Examination Of Physical Accuracy And Emotional Exaggeration On The Honey Creek Bridge Collapse, Alison R. Gaddy

All Theses

This thesis explores how truth and dramatization intersect in digital storytelling by comparing realistic and stylized simulations of the Honey Creek bridge collapse within the context of the Kate Shelley animated short. At the core of storytelling lies a tension between factual accuracy and dramatic stylization. We investigate that tension by examining how narrative truth is conveyed, distorted, or enhanced through visual dramatization by focusing on the psychology of audience perception and the motivations behind creative embellishment. The practical contribution of this research is the development of two distinct digital scene setups depicting the same Honey Creek bridge collapse event. …

The Trouble Of Energy: Theoretical Foundations Of Loop Quantum Gravity, Hallie Gift

Senior Honors Theses

While general relativity and quantum mechanics have proved to be successful theories with elegant explanations of special cases, an underlying theory is needed to harmonize their copious discrepancies. Popular theories to reconcile the two are broadly termed “quantum gravity,” which refers to theories that introduce a discretized component of gravity either by directly suggesting gravitational quanta or attempting to discretize spacetime geometry. Loop quantum gravity falls under the latter category; it respects the background independence intrinsic to general relativity while attempting to provide an explanation of underlying quantum behavior via Planck-scale-level geometrical discretization. This thesis aims to provide a primer …

From Vibration To Visualization: Building An Real-Time Audio Visualization System For Learning And Exploration Using Pyqt5, Aidan Roach

The Transdisciplinary STEAM+ Journal

This paper presents the design, development, and analysis of my real-time audio visualization system created entirely in Python using PyQt5, called WaveCatcher. The system captures live audio input from a microphone and provides simultaneous visual feedback through multiple signal representations: including a time-domain waveform, a frequency-domain FFT spectrum, a scrolling spectrogram, harmonic peak visualization, dynamic range, amplitude envelope, spectral centroid, and spectral bandwidth. These features offer insight not just into the raw structure of sound, but into how humans perceive its qualities–like timbre! This terminology may seem intimidating—it certainly was when I first began learning it—but I’ll explain all of …

Form And Fusion: The Art And Science Of Ceramics And Glass, Juniper J. Bauroth-Sherman, Kaleigh Evans

Interdivisional Studies Presentations

The first Ceramics & Art class (IDS-110-F: ST: Ceramics) has completed an immersive, interdisciplinary exploration of stained glass and we’re excited to showcase it now. Through hands-on studio work, experiments, and design projects, we combined artistic expression with the science of glass—learning how physics and chemistry shape everything from color to strength and light interaction. The students have developed practical skills in cutting, grinding, foiling, soldering, and assembling stained-glass pieces, while also experimenting with thermal stress, light transmission, and color chemistry. Glass is now understood as not just as an art form, but as a dynamic material grounded in scientific …

Fourier Analysis Of Electronic Synthesizer Waveforms, Jiayan Ling, Jack W. Maseberg

SACAD: Scholarly Activities

We compute Fourier series coefficients for some standard electronic synthesizer waveforms and provide plots of our results.

Energy Scaling And Frequency Ratios Of Particles And Constants, Alison Christina Menzmer, Donald Chakeres, Vola Andrianarijaona

Campus Research Month

We are exploring quantum aspects of various physical quantities (including Bohr radius, Rydberg constant, Planck time, and Hubble constant) and mass energies of elementary particles (including electron, neutron, and quarks). We express all physical units in an energy equivalence in Hertz, normalized to 1 Hz. Furthermore, the logarithms of these normalized energies are scaled by the logarithm of a chosen particle, which allows the generation of an Arrhenius plot exhibiting numerical structures. Our results presented in this poster show that the proton is a good candidate for an Arrhenius plot with partial fractions (1 + 1/n) and (1 - 1/n).

Tensegrity Across Biological Scales, V. M. Andrianarijaona

Campus Research Month

Over the past two decades, biology has undergone a profound conceptual shift. Living systems are no longer viewed strictly as biochemical networks; they are now understood as mechanically integrated, energy-dissipating, nonequilibrium systems governed by physical laws. Tensegrity—structural stability derived from a balance of pre-stressed tension and compression—provides the essential linking framework between molecular architecture and organismal function. This approach moves beyond "chemistry-only" models to explain how biological integrity and "mechanotransduction" (the conversion of physical force into biochemical signals) emerge from hierarchical, force-regulated networks.

Developing A Workforce To Build A Star On Earth, Vola Andrianarijaona, Angelina Castillo, Sean Walters

Campus Research Month

This study is meant to help understand why fusion has remained "30 years away" for decades and why that may finally be changing.We see nuclear fusion not merely as a physics phenomenon, but as a complex engineering challenge requiring coordination across different disciplines, including physics, materials science, electrical and mechanical engineering, systems engineering, robotics, and computer science, etc. Indeed, nuclear fusion is not just about "making atoms fuse"—it's about controlling, powering, measuring, and stabilizing one of the most extreme environments humans have ever built. Advances in superconducting magnets, new materials are bringing fusion closer to reality than ever before, and …

Machine Learning In Fundamental Physics: From Early Universe Signatures To Qcd Evolution, Brandon Stevenson

Physics Theses and Dissertations

In both cosmology and small-x quantum chromodynamics, the relevant theoretical predictions are well-defined but expensive to evaluate repeatedly over broad parameter spaces or large ensembles of simulated data. The central question of this thesis is when machine learning can accelerate those calculations without weakening the reliability of the final physics conclusions. The thesis develops and tests this idea in three settings. First, it studies the Derivative Approximation for Likelihoods (DALI) as a means of diagnosing when Fisher-matrix forecasts cease to be trustworthy in cosmological parameter inference. Second, it investigates graph-based spherical neural networks for estimating primordial non-Gaussianity directly from simulated …

Exclusive Neutral Pion Electroproduction Cross Section Measurements With A Neutral Particle Spectrometer, Mitchell R. Kerver

Physics Theses & Dissertations

Deep Virtual Compton Scattering (DVCS), the exclusive electron-proton scattering process ep →e′p′γ, provides access to generalized parton distributions (GPDs), which correlate informa tion about the longitudinal momentum and transverse spatial structure of quarks inside the nucleon. Experiment E12-13-010 in Hall C at Jefferson Lab was designed to take high-precision measure ments of the DVCS cross section over an extended kinematic range using the newly commis sioned Neutral Particle Spectrometer (NPS). The NPS features a high-resolution electromagnetic calorimeter and a streaming data acquisition system optimized for operation at high luminosities. This thesis presents the detector and analysis work carried out to …

On Links Between A Theorem Of Schoenberg, Rohlin Decompositions Of Measures, The Bochner-Minlos Theorem And The Fock Space, Daniel Alpay, Paula Cerejeiras, Palle Jorgensen, Uwe Kaehler

Mathematics, Physics, and Computer Science Faculty Articles and Research

The main goal of this paper is to gain new results in stochastics by drawing on, and combining, different areas that are normally not considered to be related. Thus, in this paper we extend the previous class of Gaussian-like functions ML which will allow for future generalized stochastic processes in infinite dimensional analysis. We show that an approach similar to the one by the classical Bochner-Minlos theorem for the white-noise case can be achieved by using Gaussian-like functions belonging to a large family -the ML_r classes (0 < r ≤∞). We show how Schoenberg’s theorem for positive definite functions on a Hilbert space allows to go beyond the classical setting of Bochner-Milnos theorem. Furthermore, we show that the application of the Rohlin’s disintegration theorem allows for a decomposition of the associated probability measures , see Theorems 3.2 and 4.3. We end this paper with several important examples of functions in these classes ML_r and provide some interesting counterexamples, e.g. Theorem 7.4, to get a …

Improving Stem Assessments: Strategies For Increasing The Accessibility And Adoption Of Two-Stage Exams, Kristina Callaghan

LSU Doctoral Dissertations

Over three decades of research have shown that students taught using active learning strategies achieve better learning outcomes compared to those taught using traditional methods. Two-stage exams, which pair a traditional exam with a group component, are an increasingly popular method for incorporating active learning within the assessment component of a course. Previous studies have shown this assessment strategy provides a variety of benefits for students, including increased engagement and collaboration, immediate feedback, and potentially increased content retention. However, the unique circumstances of each instructor can pose a non-trivial barrier to the implementation of two-stage exams. In this thesis, we …

The Link Fantastic: Detecting And Linking Simulated, Nongravitationally-Accelerating Objects With The Rubin Observatory Pipeline, Ellie White

Theses, Dissertations and Capstones

Rubin Observatory’s Legacy Survey of Space and Time (LSST) is poised to revolutionize our understanding of the Solar System. After only a few months of regular operations, Rubin has already discovered over 11,000 new Solar System bodies, and is projected to discover millions more. With discoveries pouring in, and with the development of moving object detection pipelines for routine observing, one key question is: how effectively can Rubin detect and identify objects with anomalous trajectories? The answer is of interest not only for natural bodies in our Solar System, but also in the search for technosignatures, which could be identified …

Investigating The Viability Of Fully Online Asynchronous Physics Instruction In Formal Education, Clifton W. Massey-Noel

Physics Dissertations

In this dissertation we present results from two consecutive investigations into the fully online asynchronous modality in Physics Education. We first discuss the efficacy of a fully online asynchronous section of Modern Physics held in Fall 2024. The asynchronous section is compared with four prior partially-flipped sections of the same class, two of which were held in-person, and two of which were held synchronously online. Results suggest that all three modalities can be made to be about equally as effective. We also discuss the efficacy of a fully online asynchronous section of Calculus-Based Introductory Mechanics held in Fall 2025. The …

Physics Alumni Newsletter Spring 2026, Terry Goforth

Physics Alumni Newsletter

Physics Alumni Newsletter

The Physics Alumni Newsletter is produced by the SWOSU Physics Department.

Our Engineering Physics students are recruited in fields such as electronics, aerospace, mechanical engineering, petroleum engineering and software engineering. Graduates also have careers in meteorology, architecture, education and more.

Memory Effects In Many-Body Systems, Jeffrey Beckstrand

Master's Projects

This thesis investigates memory effects in many-body systems through the MoriZwanzig Formalism for projected dynamics of a Hamiltonian System which yields the Generalized Langevin Equation (GLE). The GLE is a stochastic differential equation (SDE) that studies the dynamics of observables under the effects of many other observables in the system. Although satisfying, the GLE has a term called the Memory Kernel that encodes the past of the system and introduces a computational challenge by introducing a non-Markovian property to the equation. The kernel is often approximated by introducing a delta function, which simplifies the computation, but at the loss of …

Guitar Amplifier Directivity, Rachel C. Edelman, Brian E. Anderson, Samuel D. Bellows, Timothy W. Leishman

Directivity

No abstract provided.

An Investigation On Downwind Impacts Of The Keweenaw Peninsula On Lake-Effect Snow Events, Thomas M. Pavell

Dissertations, Master's Theses and Master's Reports

Lake-effect snow (LES) produces copious amounts of snow across the Great Lakes region. While mechanisms and impacts are well-understood, they remain difficult to observe and study over Lake Superior and the Upper Peninsula of Michigan due to a large gap in radar coverage and sparse in-situ measurements. The goal of this project aimed to characterize variables present across Lake Superior and counties on and downstream of the Keweenaw Peninsula that contribute to the formation and evolution of lake-effect snowbands. Nine different lake-effect snow events were analyzed in this project, identifying structures and features resulting from upstream passage over the Keweenaw …