Dietetics and Clinical Nutrition Commons^™

Advancing Kidney Xenotransplantation With Anesthesia And Surgery – Bridging Preclinical And Clinical Frontiers Challenges And Prospects, Xiaojian Zhang, Hailian Wang, Qin Xie, Yang Zhang, Yixin Yang, Man Yuan, Yuqi Cui, Si-Yuan Song, Jianzhen Lv, Yi Wang

Children’s Nutrition Research Center Staff Publications

Xenotransplantation is emerging as a vital solution to the critical shortage of organs available for transplantation, significantly propelled by advancements in genetic engineering and the development of sophisticated immunosuppressive treatments. Specifically, the transplantation of kidneys from genetically engineered pigs into human patients has made significant progress, offering a potential clinical solution to the shortage of human kidney supply. Recent trials involving the transplantation of these modified porcine kidneys into deceased human bodies have underscored the practicality of this approach, advancing the field towards potential clinical applications. However, numerous challenges remain, especially in the domains of identifying suitable donor-recipient matches and …

Promoting Trustworthiness Of Science: Reproducing And Verifying Agarwal Et Al's (2022) Findings Through Collaborative Endeavors, Yasaman Jamshidi-Naeini, Nicolas Escobar Velasquez, Lilian Golzarri-Arroyo, Sumayyah Ali, Luke R Howard, Stephanie Dickinson, David B Allison

Children’s Nutrition Research Center Staff Publications

No abstract provided.

Sustainability Via Active Garden Education (Sage): The Process Of Incorporating Watering Into Structured Preschool Curriculum, Rebecca E Lee, Anel Arriola, Elizabeth Lorenzo, Erica G Soltero, Jacob Szeszuski

Children’s Nutrition Research Center Staff Publications

School gardens provide rich outdoor learning opportunities for young children. Practical considerations about garden maintenance, in particular, watering, can impeed success. This manuscript chronicles the development of garden maintenance strategies in Sustainability via Active Garden Education (SAGE). SAGE installed raised-bed gardens and provided a complete curriculum focused on increasing children's active time and improving healthy eating habits while fostering garden stewardship. SAGE was implemented by trained research personnel in four early care and education (ECE) facilities in Houston, Texas (SAGE 1, Summer, 2013), one ECE facility in Phoenix, Arizona (SAGE 2, Spring, 2017), and 24 ECE facilities in Phoenix, Arizona …

Salvation And Sweet Rolls: An Examination Of Mormon Diet Books, Rachel Noorda

English Faculty Publications and Presentations

Religious diet books highlight the overlap between religious and diet cultures. This article examines the intersection of Mormonism, diet culture, and fatphobia through an analysis of Mormon diet books published between 1990 and 2015. The study explores how Mormon diet books leverage the Word of Wisdom (the LDS health code) to promote weight loss and reinforce religious obedience. By framing dietary compliance as a spiritual mandate, these texts link physical health and body size to moral and spiritual worthiness. This conflation of body and spirit, rooted in Mormon theology, amplifies fatphobia by promoting thinness as a sign of obedience and …

Clearing Ethnic Minority Roadblocks To Entry Into The Field Of Dietetics: A Mixed Analysis, Lisa C. Best

UNF Graduate Theses and Dissertations

Background - Dietitians are represented by fewer than 3% African Americans and 6% Hispanics compared with population demographics of 13% and 19% respectively. Despite 50 years of research on pipeline education, mentorship programs, cultural competency, and funding opportunities, minority participation in dietetics remains disproportionately low. At a time of increasing health care disparity, it is more important than ever to recruit and retain minorities in dietetics to optimally serve an ever increasingly diverse population.

Methods - 18 Historically Black Colleges and 26 high Hispanic census schools nationwide were contacted by email and follow-up phone call to explore and address ethnic …

Assessment Of Quality Of Life Among Patients Undergoing Semaglutide Treatment For Weight Loss, Muhammad Sameed

Honors Undergraduate Theses

Purpose: The study aims to assess the Quality of Life (QoL) among patients undergoing semaglutide treatment for weight loss. The primary hypothesis is that patients’ QoL will improve after semaglutide treatment. This can be due to losing weight, having better physical and mental health, or due to the perceived betterment in life after treatment.

Introduction: Obesity is becoming more prevalent in America, and it has a huge effect on the person's medical conditions, life expectancy, and QoL. Though there has been a surge of treatments to deter the obesity rates in America from rising. One of the more popular and …

Understanding Guardian Perceptions Of Whole-Foods Plant-Based Diets As Interventions In Pediatric Medicine, Vijay R. Luthra

Honors Undergraduate Theses

The obesity epidemic is widespread in American society, often affecting children who bear its consequences innocently. Due to a lack of nutrition knowledge, children rely on caregivers to meet their nutritional needs and instill healthy habits. This study examines parents' attitudes, knowledge, and behaviors, as well as perceived barriers to adopting a whole-foods plant-based diet (WFPD) for their children. Using a modified survey instrument by Morton et al., this study focused on parents and children regarding dietary choices. Participants were recruited from the waiting area of a pediatric clinic at the Medical College of Georgia between April and May 2023. …

The Impact Of Gestational Diabetes Mellitus And Maternal Oral Microbiome: A Scoping Review, Jaclyn P. Langan

Honors Undergraduate Theses

Background: Gestational diabetes mellitus (GDM) is a common pregnancy-related metabolic disorder associated with adverse maternal and fetal outcomes. Recent research has highlighted the potential role of the oral microbiome in the pathophysiology of various systemic conditions, including diabetes mellitus. However, the impact of GDM on the maternal oral microbiome remains relatively understudied. Understanding alterations in the oral microbiome during pregnancy complicated by GDM could provide valuable insights into the mechanistic links between systemic metabolic disorders and oral health.

Objective: The objective of this scoping review was to comprehensively examine the existing literature on the relationship between GDM and maternal oral …

Examining The Relationship Between Physical Health Behaviors And Mental Health Outcomes In Female Hispanic College Students, Alexandra St. Laurent

Honors Undergraduate Theses

The current state of mental health in college students is a universal concern. Female college students are reporting more depression, anxiety, and stress symptoms than ever before. Physical activity and diet quality can positively influence mental health symptoms. Current research provides scarce evidence that examines the relationship of these health behaviors and outcomes in the Hispanic female population. The primary aim of this study is to examine the relationship between physical health behaviors and mental health outcomes in Hispanic female college students. This is a cross-sectional study using a self-report survey to collect data from approximately 109 Hispanic female college …

Assessing The Impact Of Olive Oil And Flaxseed Oil Supplementation On Hypertension And Inflammation In Healthy And At-Risk Adults, Tara Bess Mcnabb

Graduate Theses, Dissertations, and Problem Reports (ETD)

Background: Supplementation of olive oil and flaxseed oil and their impacts on hypertension and inflammation have been reported for healthy and hypertensive adults. However, a comprehensive systematic literature review and meta-analysis on the preventive benefit of plant oil supplementation in healthy adults and adults at risk of inflammation inducing hypertension is lacking.

Objective: to evaluate human clinical trials assessing the impact of olive oil and flaxseed oil capsules on systolic blood pressure (SBP) and diastolic blood pressure (DBP) and select inflammatory markers in non-hypertensive and at-risk adults of hypertension.

Data sources: Four databases were searched in October 2023 …

Silver Diamine Fluoride As A Caries Management Option For The Young Child, Giovana Anovazzi Medeiros Dds, Msc, Phd, Chia-En Tsai Dds, Ms, Nita Singh Dds, James R. Boynton Dds, Ms

The Journal of the Michigan Dental Association

Dental caries is among the most-common childhood diseases around the world, and neglected caries can result in pain, infection, and can have a negative cascading impact on a child’s overall well-being. Definitive care of these lesions involves restorative procedures and/or extractions, but these treatment options require some level of child cooperation, which can sometimes be a challenge with very young children.

Silver diamine fluoride (SDF) is a non-invasive treatment intended to arrest the caries process. SDF is a liquid solution that contains a high concentration of silver and fluoride ions and has been used as an alternative agent for treating …

Pediatric Dentists’ Considerations Concerning Obesity-Related Education For Parents Of Young Children: Who Should Educate About What, How And When?, Arianne Swanson Dds, Ms, James R. Boynton Dds, Ms, Larry B. Salzmann Dds, Yu-Ju Yang Dds, Marita R. Inglehart Dipl. Psych., Dr. Phil., Dr. Phil. Habil

The Journal of the Michigan Dental Association

This study aimed to explore pediatric dentists' perspectives on obesity-related interventions for parents of young children. A web-based survey was administered to 210 American Academy of Pediatric Dentistry members. Findings revealed that respondents considered it important for various healthcare professionals, especially pediatricians and nurse practitioners, to engage in obesity-related parent education. Strong consensus existed on educating parents about the link between early childhood caries and diet, soft drink and fruit juice consumption, and healthy snacking. The study also found positive attitudes correlated with increased engagement in objective weight determination, data collection, and diet/nutrition counseling.

Randomized Pilot Study Examining An Online Diet Intervention To Increase Intake Of Fruits And Vegetables Among Healthy Adults, Diana E Kolb, Sarah E Deemer, Evaclaire Synkowski, Stephanie L Silveira

Faculty, Staff and Student Publications

Intake of fruits and vegetables (F&V) is related to health outcomes. The purpose of the study was to test an online diet program promoting F&V intake among healthy adults. Twenty-three participants were randomly assigned to complete an 8-week intervention condition (#800gChallenge®) or wait-list control condition. In weeks 1-4, intervention participants were asked to interact with an application reporting (a) whether they met their daily 800g F&V goal, (b) if their 800g of F&V was from a variety of sources, and (c) reading of daily educational material. Weeks 1-4 included weekly Zoom check-in meetings. Weeks 5-8 were autonomous, wherein participants reported …

Changes In Unhealthy Food Consumption Among Vulnerable Elementary-Aged Children In The United States During The Covid-19 Pandemic: A Serial Cross-Sectional Analysis, Nivedhitha Parthasarathy, Nalini Ranjit, Ru-Jye Chuang, Christine Markham, Mike Pomeroy, Jacqueline Noyola, Deepali K Ernest, Shreela V Sharma

Faculty, Staff and Student Publications

Objective: Several studies suggest that during the early pandemic, amidst socioeconomic instability, children from underserved families were more likely to resort to consuming cheaper, lower-quality foods with longer shelf lives. This study investigated the change in unhealthy food consumption across different phases (pre, early, mid) of the COVID-19 pandemic, and whether the strength of association between unhealthy food consumption and household socioeconomic disadvantage (HSED) varied across phases of the pandemic.

Methods: This study utilized serial cross-sectional data collected from low-income families enrolled in a school-based food co-op, Brighter Bites. Secondary data analysis included 5,384 surveys from families who had complete …

A Virtual Culinary Medicine Intervention For Ethnically Diverse Individuals With Type 2 Diabetes: Development Of The Nourishing The Community Through Culinary Medicine, Lorena Macias-Navarro, John Wesley Mcwhorter, Diana C Guevara, Sarah S Bentley, Shreela V Sharma, Jennifer H Torres, David Ai, Natalia I Heredia

Faculty, Staff and Student Publications

Virtual culinary medicine education interventions have the potential to improve dietary behaviors, nutrition knowledge, cooking skills, and health outcomes for ethnically diverse individuals with type 2 diabetes. The purpose of this study is to describe the adaptation of the Nourishing the Community through Culinary Medicine (NCCM) program for virtual delivery, and the protocol for pilot testing this intervention. The intervention includes five 90-min virtual NCCM sessions streamed live from a Teaching Kitchen. Feasibility outcomes are recruitment, retention, acceptability, and satisfaction. Short-term effectiveness outcomes are measured through self-administered questionnaires, including perceived health, average daily servings of fruits and vegetables, frequency of …

Differing Impacts Of The Covid-19 Pandemic On Farmers And Intermediaries: Insights Into The Ecuadorian Cocoa Value Chain, Guillermo Zambrano, Lina M Tennhardt, Moritz Egger, Karen Ramírez, Adriana Santos, Byron Moyano, Michael Curran

Faculty, Staff and Student Publications

The COVID-19 pandemic generated diverse impacts and responses in agricultural value chains worldwide. Cocoa is a key crop for Ecuadorian exports, and the analysis of effects the pandemic had on value chain actors contributes to the understanding of their individual capacities to coping with a major shock. The purpose of this study was to assess the number and severity of impacts and responses implemented by two links in the cocoa value chain to the pandemic, based on a survey of 158 cocoa farmers and 52 cocoa intermediaries from the main cocoa-producing provinces of the northern coast of Ecuador in 2021. …

Family Structure, Family Transitions, And Child Overweight And Obesity: Comparing Australia, The United Kingdom, And The United States, Sadie A. Slighting, Kirsten Rasmussen, Mikaela J. Dufur, Jonathan A. Jarvis, Shana Pribesh, Alyssa J. Alexander, Carolina Otero

STEMPS Faculty Publications

Growing rates of childhood obesity globally create concern for individuals' health outcomes and demands on health systems. While many policy approaches focus on macro-level interventions, we examine how the type of stability of a family structure might provide opportunities for policy interventions at the micro level. We examine the association between family structure trajectories and childhood overweight and obesity across three Anglophone countries using an expanded set of eight family structure categories that capture biological relationships and instability, along with potential explanatory variables that might vary across family trajectories and provide opportunities for intervention, including access to resources, family stressors, …

Exploring The Health Benefits Of Raw White Garlic Consumption In Humans: A Mini Review, Rebeka Fejes, Catherine P. Bondonno, Simone Radavelli-Bagatini, Tilman Kühn, Karl Heinz Wagner

Research outputs 2022 to 2026

Introduction: Raw white garlic, a fundamental food in both culinary and medicinal practices globally, has gained attention for its potential health benefits. Despite widespread use, clinical research has predominantly focused on aged black garlic or garlic extracts, leaving raw white garlic consumption in humans underexplored. This mini review aims to summarize the evidence from clinical and observational studies on the health effects of raw white garlic consumption. Methods: A search in PubMed and Scopus databases was conducted to identify clinical and observational studies on raw white garlic consumption. Twelve clinical trials and 10 observational studies meeting the predefined inclusion criteria …

Standardizing Nasogastric Tube Securement: A Quality Improvement Initiative, Shannon Lee Thompkins

Graduate Theses, Dissertations, and Problem Reports (ETD)

Problem: At a large academic medical center located in the northeastern United States, nasogastric tubes (NGT) were traditionally secured with tape. The institutional policy was nonspecific with no written procedure. The inconsistent use of nasal bridle securement devices (NBSD) and predominant use of tape has the potential to lead to a high rate of NGT dislodgement.

Background: NGT complication and dislodgement rates range from 2%-36% (Gimenes et al., 2019). Stabler et al. (2018) report 29%-63% NGT dislodgement rates in critically ill patients. Patients with intracranial hemorrhage dislodge NGTs in 25% of patients (Rahman et al., 2022)

Available Knowledge: Based on …

Carotenoids And The Associations With Gut Microbiota Bacterial Populations In Chronic Kidney Disease Hemodialysis Patients, Andrea Kendall

Theses and Dissertations

Background: With increased prevalence and mortality of chronic kidney disease (CKD), treatment by renal replacement therapy using hemodialysis (HD) has increased in parallel. Emerging evidence suggests that gut microbiota play an important role in the progression of CKD; influential dietary factors have not been studied exhaustively to date.

Objective: To explore the relationships between dietary carotenoid intake, the abundance of specific gut microbiota, and symptom-related outcomes in patients with CKD on HD.

Methods: This cross-sectional study investigated the gut microbiota characteristics relative to carotenoid intake in CKD subjects on HD in central Illinois (n = 20). The Block Dialysis …

Association Between Early Childhood Feeding Practices And Parental Perception Of Picky Eating, Yue-Liang Brewerton, Anoud Mohammad, Linda Navarro, Cindy Kosch, Gurinder Bains, Liang Ji, Edward Bitok

Loma Linda University Research Reports

Introduction: This study aimed to investigate the association between early childhood feeding practices and picky eating behaviors in children aged 5-10 years.

Methods: Forty-three parents or legal guardians of children aged 5-10 completed the Child Feeding Questionnaires (CFQ) and the Children’s Eating Behavior Questionnaire (CEBQ) to assess parental control in child feeding and child eating behaviors, respectively. Logistic regression was used to analyze the relationship between the exposure and outcome variables.

Results: Infants fed store-bought food didn't differ significantly in picky eating from those fed self-made food, challenging conventional assumptions. Additionally, while socioeconomic status and parental education didn't show significant …

The Effects Of Hydration Status On Grip Strength, Loradelle Feri, Jordan Sales, Angela Li, Devon Cannata, Cindy L. Kosch, Gurinder Bains, Liang Ji, Everett B. Lohman, Lee Berk, Edward K. Bitok

Loma Linda University Research Reports

Introduction: This study aimed to investigate the influence of hydration status on hand grip strength in a sample of the general population.

Methods: Fourteen participants (4 males and 10 females) aged 18 and older, were recruited from the Loma Linda University area. Participants underwent multiple clinic visits, where they were randomly assigned to either optimal or suboptimal hydration conditions. Measurements included hand grip strength using a dynamometer, extracellular water ratio via bioimpedance analysis, and urine specific gravity.

Results: There was no significant differences in hand grip strength, extracellular water ratio, or urine specific gravity between optimal and suboptimal hydration states. …

The Effects Of Daily Magnesium Citrate Supplementationon Grip Strength, Carolina Cano, Holly King

Loma Linda University Research Reports

Magnesium (Mg) is thought to play an essential role in physical strength because it catalyzes more than 300 enzymatic reactions involved in energy metabolism and cell growth. Magnesium also aids in the hydrolysis of ATP in glycolysis, acting as a coenzyme in three critical reactions and in crossbridge formation in the muscle contraction cycle. Despite these roles, approximately 60% of the US adult population does not meet the RDA for Mg. Previous studies found inconsistent results on the effects of Mg on physical performance. However, most studies agreed on magnesium's potential as an ergogenic aid.

Assessment Of Nutrition Knowledge And Implementation Of Nutrition Education In Pilots, Tarika Chhabra, Susan Kumon, Savanna Malki, Bryan Ferrell, Cindy Kosch, Edward Bitok, Gurinder Bains, Lida Gharibvand

Loma Linda University Research Reports

This study assessed the effectiveness of a nutrition education program for Certificated Flight Instructors (CFIs). The program consisted of six video modules and briefs on various nutrition topics. Thirty-one CFIs participated in the study, and their nutrition knowledge was assessed before and after the program. The results showed a statistically significant increase in nutrition knowledge scores following the intervention (p < .001). Participants also reported that the program helped them improve their dietary habits. These findings suggest that nutrition education can be an effective way to improve the health and well-being of CFIs and potentially other populations.

Effects Of Intuitive Eating Principles And Magnesium Glycinate On Quality Of Life, Body Satisfaction, And Stress In Early- And Middle-Aged Adults, Numydia Cotry, Taylor Kalinowski, Angel Wilensky

Loma Linda University Research Reports

This study investigated the impact of combining Intuitive Eating (IE) principles with magnesium glycinate supplementation on adults aged 18 to 49. Participants were split into two groups: one practicing IE alone and another receiving magnesium supplementation alongside IE. Results showed significant improvements in body satisfaction, stress levels, and overall health among those receiving magnesium. Qualitative data indicated enhanced body awareness and well-being with IE. This suggests a promising synergy between IE and magnesium supplementation for better health and quality of life. However, further research with larger samples and longer durations is warranted.

Dietitian & Physician Preferences Of Fiber Use In Enteral Nutrition: A Pilot Study, Holly Gauthun, Thy Pham, Cory Gheen, Liang Ji, Edward Bitok, Susie Ray

Loma Linda University Research Reports

This pilot study examines the beliefs and preferences regarding fiber use in enteral nutrition (EN) among physicians and registered dietitians (RDs) for hemodynamically stable critically ill patients. A total of 30 RDs and 12 physicians participated. The majority of both physicians (80%) and RDs (83%) supported fiber use in EN for these patients. All participants with over ten years of experience and all Certified Nutrition Support Clinicians (CNSCs) endorsed fiber use. Despite expectations, no significant difference in support was found between RDs and physicians. The study reveals a noteworthy shift towards endorsing fiber use in enteral nutrition for hemodynamically stable …

Effectiveness Of Education For Type 1 Diabetes Patient's Caregivers At Loma Linda University Health, Epiphaneia Juarez

Loma Linda University Research Reports

Diabetes education is essential for patients and families to improve quality of life and minimize the challenges and complications of living with Type 1 Diabetes Mellitus (T1DM). The aim of the research study is to evaluate the knowledge and nutritional practices of caregivers in the management of T1DM in pediatric patients. 20 subjects were recruited at the Loma Linda University Children’s Hospital (LLUCH) Pediatric Diabetes Center before their outpatient T1DM class. A demographic survey, nutrition knowledge survey (NKS), and a 24-hour recall were administered to participants. The Mann-Whitney U test was used to evaluate NKS total score among binary variables …

Adjusting For Covariates Representing Potential Confounders, Mediators, Or Competing Predictors In The Presence Of Measurement Error: Dispelling A Potential Misapprehension And Insights For Optimal Study Design With Nutritional Epidemiology Examples, Roger S Zoh, Diana M Thomas, Carmen D Tekwe, Xiaoxin Yu, Colby J Vorland, Nikhil V Dhurandhar, David M Klurfeld, David B Allison

Children’s Nutrition Research Center Staff Publications

Background: Variables such as dietary intake are measured with error yet frequently used in observational epidemiology. Although this limitation is sometimes noted, these variables are still often modeled as covariates without formal correction or sincere dialogue about measurement unreliability potentially weakening the validity of statistical conclusions. Further, larger sample sizes increase power (bias) to detect spurious correlations. Counterintuitively, recent work suggested a non-monotonic relationship between confounder unreliability and how much controlling for the confounder reduces (or induces) bias when testing for an exposure-outcome association. If true, such non-monotonicity would be especially concerning for applications such as nutrition, where measurement reliability …

Catalyzing Communities Of Research Rigour Champions, Audrey C Brumback, William X Q Ngiam, Dana M Lapato, David B Allison, Christin L Daniels, Michael Dougherty, Haley F Hazlett, Kara L Kerr, Susan Pusek, Naomi Schrag

Children’s Nutrition Research Center Staff Publications

The biomedical sciences must maintain and enhance a research culture that prioritizes rigour and transparency. The US National Institute of Neurological Disorders and Stroke convened a workshop entitled 'Catalyzing Communities of Research Rigor Champions' that brought together a diverse group of leaders in promoting research rigour and transparency (identified as 'rigour champions') to discuss strategies, barriers and resources for catalyzing technical, cultural and educational changes in the biomedical sciences. This article summarizes 2 days of panels and discussions and provides an overview of critical barriers to research rigour, perspectives behind reform initiatives and considerations for stakeholders across science. Additionally, we …

Breakfast Skipping In College Students And Its Association With Eating Behaviors, Rebekah E. May

Honors Undergraduate Theses

Background: Breakfast is important in maintaining optimal diet quality and decreasing preventable diet-related disease later in life. Breakfast skipping is highly prevalent in the college population, potentially decreasing self-regulation and diet quality and increasing habits of overeating. However, specific eating styles and diet quality have yet to be studied in breakfast skippers.

Objective: To explore and compare the characteristics of eating style, self-regulation, and diet quality among college students between a day when breakfast is skipped and a day when breakfast is consumed.

Methodology: Undergraduate students (n=103) participating in this observational crossover study completed demographics, the Self-regulation of Eating Behavior …