Dentistry Commons^™

A Review Of External Cervical Resorption, Sarah Makkiyah, Max Kazantcev

Excellence Day

Invasive cervical resorption (ECR) is a complex form of external resorption. It is distinguished by its localization, its invasive nature, and the formation of a mineralized replacement tissue resembling cellular cementum. During initiation of ECR, the portal of entry is the cementum below the gingival epithelium, and resorption starts with localized destruction and removal of PDL. Response to PDL injury includes formation of a blood clot and inflammation, followed by granulation tissue, recruitment of macrophages, and multinucleated-cell differentiation.

Three-Dimensional Analysis Of Nasoalveolar Molding Treatment (Nam) Effects In Unilateral Cleft Lip, Alveolus, And Palate Patients, Sophie Dipietro, Meghan Hansen, Yoon Weon Suh

Excellence Day

Background: NAM therapy is a non-surgical method that aims to improve both the aesthetic and functional outcomes of cleft lip and palate treatment in newborns. It applies controlled pressure to the cleft region, allowing for the reshaping of the area. However, further research is necessary to gain a deeper understanding of the underlying factors that influence cleft palate closure patterns and identify the regions that play the most significant role in approximating clefts. Objective: The aim of this study was to assess the impact of pre-surgical nasoalveolar molding (NAM) on infants with unilateral cleft lip and palate, with a hypothesis …

3d Printing In Restorative Dentistry, Sucharu Ghosh, Mahban Zarei, Parul Kumar, Priya Prasannakumar, Patrick Pansoy

Excellence Day

The term 3 D printing is generally used to describe a manufacturing approach that builds objects one layer at a time, adding multiple layers to form an object The presentation aims to provide a comprehensive understanding of the use of 3 D printing technology in restorative dentistry and its potential impact on the field

Human Dental Pulp Stem Cell Culture Model For Studies On Etiopathogenesis Of Nonsyndromic Cleft Lip With Or Without Cleft Palate Anomaly, Tyler Starley, Jonathan Starley, Harrison Truman

Excellence Day

Nonsyndromic cleft lip with or without cleft palate (NSCLP) occurs approximately in 1 of 700 live births. It has a serious impact on a patient during the whole life. It was shown that it can be prevented by supplementation of folic acid. However, much more needs to be known about etiopathogenetic factors and molecular mechanisms leading to NSCLP in order to personalize its prevention. Basic science information on etiology and pathogenesis of NSCLP was obtained from animal experiments. Clinical studies and trials showed efficacy of prevention by folic acid supplementation. A cell culture model is needed for studies on cellular …

Conventional Vs Digital Impressions, Vinitha Gopal-Murthy, Mirna Merhi-Boghossian, Geet Shukla

Excellence Day

Summary: A dental impression is a negative replica of the hard and soft tissues of the oral cavity. Conventional impressions help make dental casts which are used for diagnostic and therapeutic purposes. Digital impression involves a 3D intraoral scanning, which is processed by the impression involves a 3D intraoral scanning, which is processed by the computer to generate a virtual replica of the tissues in the mouth. In siloxanes, poly sulfides, addition and condensation silicones are used. Digital impressions can be a closed system like CEREC, that relies on one manufacturer and technology for CAD/CAM procedures or open systems like …

Comparison Of Various Post-Systems In Endodontically Treated Teeth, Viraj Ketkar, Hemal Pandya, Fariba Yaghoobi

Excellence Day

Summary: This study aims to compare various post-systems used in endodontically treated teeth. A comprehensive literature review was conducted to identify studies that compared different post systems in endodontically treated teeth. The inclusion criteria included studies comparing two or more post-systems regarding clinical and/or radiographic outcomes. The studies included in the review evaluated different types of post systems, including prefabricated metal posts, custom-made metal posts, fibre-reinforced posts, and zirconia posts. The outcomes evaluated included retention rates, fracture rates, and marginal adaptation. Cast posts offer customization benefits but need multiple appointments, while prefabricated posts are widely used for their various material, …

The Effects Of Cigarette Smoke On Sars-Cov-2 Infection In The Oral Cavity – A Preliminary Literature Review, Youyoung Min

Excellence Day

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been suggested to replicate and be found in the oral cavity. The objective of this preliminary literature review is to determine the effects of cigarette smoke on the risk of SARS-CoV-2 infection in the oral cavity, and the risk for the overall health. SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), uses the ACE2 receptor and protease TMPRSS2 for entry into host cells. The cigarette smoke condensates upregulates these receptors in human gingival epithelial cells. Because smoking can alter expression of COVID-19 viral entry genes, smokers are more susceptible to SARS-CoV-2 infection. Several …

Insight - Summer 2023, Dugoni School Of Dentistry

Insight

Welcome to the summer 2023 issue of Insight, a newsletter celebrating the accomplishments of our community of scholars. We aim to spotlight insights from people at the Dugoni School working in all areas of scholarship, including clinical or biomedical research, the scholarship of teaching and learning, improvement of the health care system, and professional partnerships that advance the field.

Contact Point Spring 2023, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.

The Role Of Nod-Like Receptors In Innate Immunity, Cassio Luiz Coutinho Almeida-Da-Silva, Luiz Eduardo Baggio Savio, Robson Coutinho-Silva, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

The innate immune system in vertebrates and invertebrates relies on conserved receptors and ligands, and pathways that can rapidly initiate the host response against microbial infection and other sources of stress and danger. Research into the family of NOD-like receptors (NLRs) has blossomed over the past two decades, with much being learned about the ligands and conditions that stimulate the NLRs and the outcomes of NLR activation in cells and animals. The NLRs play key roles in diverse functions, ranging from transcription of MHC molecules to initiation of inflammation. Some NLRs are activated directly by their ligands, while other ligands …

Insight - Spring 2023, Dugoni School Of Dentistry

Insight

Welcome to the spring 2023 issue of Insight, a newsletter celebrating the accomplishments of our community of scholars. We aim to spotlight insights from people at the Dugoni School working in all areas of scholarship, including clinical or biomedical research, the scholarship of teaching and learning, improvement of the health care system, and professional partnerships that advance the field.

Interactions Between Silica And Titanium Nanoparticles And Oral And Gastrointestinal Epithelia: Consequences For Inflammatory Diseases And Cancer, Cassio Luiz Coutinho Almeida-Da-Silva, Leticia Ferreira Cabido, Wei Chun Chin, Ge Wang, David M. Ojcius, Changqing Li

All Dugoni School of Dentistry Faculty Articles

Engineered nanoparticles (NPs) composed of elements such as silica and titanium, smaller than 100 nm in diameter and their aggregates, are found in consumer products such as cosmetics, food, antimicrobials and drug delivery systems, and oral health products such as toothpaste and dental materials. They may also interact accidently with epithelial tissues in the intestines and oral cavity, where they can aggregate into larger particles and induce inflammation through pathways such as inflammasome activation. Persistent inflammation can lead to precancerous lesions. Both the particles and lesions are difficult to detect in biopsies, especially in clinical settings that screen large numbers …

Trident - Spring 2023, Dugoni School Of Dentistry

Trident

The spring 2023 issue of the orthodontics alumni newsletter at University of the Pacific, Arthur A. Dugoni School of Dentistry

Skeletal And Dental Treatment Effects In Class Ii Subdivision Malocclusions: A Cbct Study, Jaime Kika Masunaga

Orthodontics and Endodontics Theses

Objectives: The purpose of this study is to determine the skeletal and dental contributions in the orthodontic correction of Class II subdivision malocclusions using cone-beam computed tomography (CBCT) analysis. Methods: 50 Patients that completed non-surgical orthodontic treatment at the University of the Pacific Graduate Orthodontic Clinic with initial Class II subdivision malocclusions were identified. Patients were classified as growing or non-growing, and further categorized if a skeletal asymmetry was present. Final records were assessed with 3-dimensional CBCT. Wilcoxon signed-rank tests were used to compare linear skeletal, angular, and dental measurement differences between pre- and post-treatment CBCTs on Class I and …

Characteristics Of Gingival Crevicular Fluid Flow During Orthodontic Treatment With Invisalign, Nina Stevens

Orthodontics and Endodontics Theses

OBJECTIVES. Studies on quantitative relationships between magnitude of force applied to a tooth root and formation of gingival crevicular fluid (GCF) biomarkers (volume, concentrations of cytokines, enzymes, etc.) in clinical settings are lacking. This study aims to answer the question: What can analysis of GCF flow dynamic characteristics inform us about orthodontic tooth movement in a patient treated by Invisalign? METHODS. In three participants, two GCF samples were collected from five maxillary and five mandibular teeth during start, middle and end of Invisalign treatment. Plaque index and pocket depths were determined. Periopaper strips (Oraflow) were used for collection of GCF, …

Cephalometric And Dental Changes Observed In Deep Overbite Correction Using Clear Aligners, Valerie Hernandez-Blouin

Orthodontics and Endodontics Theses

Introduction: The objective of this study was to investigate the cephalometric and dental changes observed in nongrowing, deep overbite patients of varying mandibular planes treated with Invisalign® (Align Technology, San Jose, CA). Methods: This retrospective study included 51 patients (27 females and 24 males, aged 33.01 ± 14.74; initial overbite of 4.6 ± 0.83 mm; average treatment period of 1.89 ± 0.85 years; average refinements of 2 ± 1.51). The sample was consecutively treated at the University of the Pacific Resident Orthodontic Clinic and one private practice from 2014-2023. The sample was further divided into 2 groups: patients with an …

Assessing Treatment Effects Of Invisalign First Compared To Maxillary Expanders And Fixed Appliances In Mixed Dentition Patients, Parisa Moravedje Torbaty

Orthodontics and Endodontics Theses

Objectives: This retrospective cohort study compared vertical and transverse changes in mixed dentition patients treated with Invisalign First System (IFS) to those treated with rapid maxillary expansion and fixed appliances (RME), as well as control groups. We also assessed the efficiency of dental arch expansion with IFS. Methods: The study included 80 mixed dentition patients, with 40 in each group (IFS and RME) and 40 controls from the AAOF Legacy Collection. We analyzed skeletal and dental vertical dimension changes from lateral cephalometric radiographs and arch width changes on study casts between pre-treatment (T1) and post-treatment (T2). Results: Age at T1, …

Class Ii Malocclusion Correction With Invisalign: A Retrospective Study, Stacey Moon

Orthodontics and Endodontics Theses

Objectives: This study aimed to examine the treatment outcome of correcting class II malocclusion with maxillary molar distalization using clear aligners in both growing and nongrowing patients. Material and Methods: Total of 42 patients (31 growing and 11 non-growing) who underwent non-extraction clear aligner therapy with maxillary molar distalization were selected and compared to 20 subjects who did not undergo orthodontic treatment were selected from American Association of Orthodontists Foundation (AAOF) legacy collection. Thirteen cephalometric measurements and molar relationships on the digital casts at pre-treatment (T1), end -of-active-treatment (T2) for the treatment group (growing and non-growing) and control group were …

3-D Automated Landmark Identification On Cone-Beam Computed Tomography Using In Vivo: Accuracy And Reliability, Young-Eun Stephanie Jung

Orthodontics and Endodontics Theses

Objectives: The aim of this study was to assess the accuracy and reliability of a fully automated landmark identification (ALI) system in automatically locating landmarks, in comparison to assessments made by human judges. Materials and Methods: We collected a total of 76 cone-beam computed tomography (CBCT) images. Following a calibration process, two human judges utilized In Vivo7 Software (Anatomage, San Jose, California) to locate 31 landmarks in the x, y, and z coordinate planes on the CBCT images. A ground truth dataset was created by averaging the landmark coordinates identified by the two human judges for each landmark. The accuracy …

Clinicians’ Judgment To Recommend Phase I Mixed Dentition Treatment, Yidi Liu

Orthodontics and Endodontics Theses

The timing and necessity of Phase I mixed dentition treatment in orthodontics have long been subjects of debate. This study aims to explore the level of agreement among clinicians in recommending Phase I treatment, the rationales behind such decisions, and the implications for Phase II treatment. MATERIALS and METHODS: A series of three surveys were administered to faculty members at the University of the Pacific, focusing on various aspects of Phase I and Phase II treatments. RESULTS: The study found a mild level of agreement among clinicians in recommending Phase I treatment, with transverse issues being the most cited reason. …

Medical Marijuana Knowledge And Attitudes: A Survey Of Dental And Dental Hygiene Faculty And Students, Dara Szyliowicz, Andrew Young, Yesha Golwala

Eberhardt School of Business Faculty Datasets

Background:

Medical Marijuana (MM) use is increasing, requiring healthcare professionals, such as dentists, to possess a working knowledge of MM. Previous studies have indicated that MM education is lacking in current healthcare education.

Methods:

A 50-question survey was created to assess, in detail, dental and dental hygiene faculty and students knowledge, practice, and attitudes toward MM, and to identify possible correlations between responses. The survey was modeled after a previous survey conducted amongst practicing pharmacists. All faculty dentists, faculty dental hygienists, students and residents at the Arthur A. Dugoni School of Dentistry, University of the Pacific, were invited by email …

Pharmacology For National Board Examination, Krina Shah

Dugoni School of Dentistry Student Scholarly Works

This pharmacology study guide is designed to provide students preparing for the National Boards exam with a clear and concise visual aid in the form of systemic flow charts. Each flow chart is organized by drug class and includes information on the mechanism of action, indications, contraindications, dosages, and common adverse effects for each drug within the class. By using this study guide, students can easily navigate through the complex world of pharmacology and feel confident in their ability to succeed on the pharmacology section of the National Board exam. The study guide for pharmacology is significant in several ways. …

Nasoalveolar Molding In Unilateral Cleft Lip And Palate: A Three-Dimensional Analysis, Yoon Weon Christina Suh

Orthodontics and Endodontics Theses

Objectives: This study aimed to three-dimensionally analyze the effects of pre-surgical nasoalveolar molding in unilateral cleft lip and palate patients. Methods: The sample was collected from three centers and consisted of 132 digital dental casts of patients pre- and post- NAM. Landmarks and measurements were identified on each cast and the changes from pre- to post-NAM were recorded and analyzed. Results: Post-NAM, we observed a mean decrease of 5.18mm in 3D cleft width, 1.78mm decrease in sagittal cleft gap, 1.34mm decrease in the anterior arch width, 2.27mm increase in the posterior arch width, a greater inward rotation of the greater …

A Flash Of Inspiration: Enhancing Dental Student Drug Recognition, Benjamin D. Zeitlin

All Dugoni School of Dentistry Faculty Articles

Students preparing for exams often retain the complexities of a subject but instant recognition and recall is something that, for most, takes time and consistent, repeated study to establish. This can happen through well-managed spaced learning (iterative study) prior to examination; given the preponderance of massed study (cramming for a subject),1 however, many students require long-term exposure in the clinic to patients’ medical histories to achieve instant recall. Understanding the applied pharmacology of common drugs is a current American Dental Association accreditation standard. Ideally, dental students should demonstrate a consistent level of basic drug recognition and the ability to retrieve …

Insight - Fall 2022, Dugoni School Of Dentistry

Insight

Welcome to the autumn 2022 issue of Insight, a newsletter celebrating the accomplishments of our community of scholars. We aim to spotlight insights from people at the Dugoni School working in all areas of scholarship, including clinical or biomedical research, the scholarship of teaching and learning, improvement of the health care system, and professional partnerships that advance the field.

Contact Point Autumn 2022, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.

External Apical Root Resorption Of Maxillary Incisors Following Orthodontic Treatment In Patients With Short Root Anomaly: A Cbct Study, Eric Le, Jonas Bianchi, Heesoo Oh

Orthodontics and Endodontics Theses

Introduction: The purpose of this study was to evaluate the amount of external apical root resorption (EARR) secondary to orthodontic treatment in patients with Short Root Anomaly (SRA) using Cone Beam Computed Tomography (CBCT) at the University of the Pacific Orthodontic Clinic. Material and Methods: In this retrospective study, CBCTs of forty-eight SRA patients who underwent orthodontic treatment were selected from the graduate orthodontic clinic. CBCTs before and after treatment were analyzed to measure root length changes on the upper central and lateral incisors. Results: Differences between the two methods of assessing SRA severity occurred between categorizing mild and moderate …

Three-Dimensional Analysis Of Skeletal Changes And Stability In Fixed Orthodontics Vs. Invisalign Therapy In Patients Undergoing Surgery First Approach, Mojan Mirnia, Hyeon-Shik Hwang, Jonas Bianchi

Orthodontics and Endodontics Theses

Introduction: The objective of this retrospective longitudinal study was to assess and compare the surgical changes and stability of the maxilla, mandible, and mandibular condyle, in patients who have undergone surgery first approach (SFA) followed by conventional braces or Invisalign (Inv) treatment. Methods: Thirty patients had a cone beam computed tomography (CBCT) exam taken at three timepoints: T1 (presurgery), T2 (immediately after surgery), and T3 at the completion of orthodontics treatment. After the cranial base registration, twenty-seven landmarks were located on each time point using axial, sagittal, and coronal cross-sectional views in the ITK-SNAP software. In addition, seventeen skeletal angular …

Efficacy Of Caries Detection And Characterization Using Near-Infrared Imaging Technology In The Itero Element 5d Intraoral Scanner In Comparison To Clinical-Reference Standard Bitewing Radiographs In A Pediatric Population, Kyle Cuenin, James Chen

Orthodontics and Endodontics Theses

Introduction: Near infrared imaging (NIRI) uses non-ionizing radiation in the near-infrared spectrum to differentially scatter light off tooth surfaces. This generates images that allow for interproximal caries detection, which have been proposed as an alternative to radiographic detection. The new iTero Element 5D intraoral scanner (Align Technology) has integrated NIRI capture and viewing technology but has not been specifically studied in a pediatric population. Therefore, the goal of this study was to assess clinicians’ abilities to detect and characterize caries in pediatric patients using this instrument. Methods: Bitewing (BW) radiographs and a NIRIenabled intraoral scan were captured on 17 pediatric …

Searching For Association Of Gsk3Β Rs13314595, Msx1 Rs3821949, Tgfβ3 Rs3917201, And Bmp4 Rs17563 With Non-Syndromic Cleft Lip And Palate, Gabrielle Wainwright, Marie M. Tolarová Md, Phd, Drsc, Mirek Tolar

Orthodontics and Endodontics Theses

Introduction: Non-syndromic cleft lip with or without cleft palate (NCL±P) is characterized by a multifactorial etiology with both genetic and environmental factors playing a role in its embryonic development. Recent genetic studies have identified susceptibility loci and genetic variations in several genes that were associated with the risk of developing NCL±P. The purpose of this study was to investigate the association of MSX1, BMP4, TGFβ3, and GSK3β gene variants with NCL±P in a casecontrol data set from Karaikal, India. Methods: The case sample consisted of 331 individuals who were diagnosed with CL (bi/unilateral cleft lip), CLP (bi/unilateral cleft lip and …