Dentistry Commons^™

Managing Patient Expectations With Implant Treatment, Daniel B. Kamran, Mark Booth Dds, Eduardo Gonzalez Dds, Ed Shaw Dds

Excellence Day

This patient came to University of the Pacific, Arthur A. Dugoni School of Dentistry to get implants and implant crowns to improve his smile, replacing his upper partial denture. Different approaches were made by the faculty to arrive at best outcomes, which took four years for the patient to receive the treatment he wanted. This abstract will further detail how the treatment was conducted and the results afterwards.

A Modified “Wound Healing” And Hypoxia Model In Vitro, Schuyler G. Tang, Isabel Kwon, Marie M. Tolarova, Mirek Tolar

Excellence Day

Closing a wound may resemble some aspects of fusion of embryonic processes during development of face. In addition, both are sensitive to oxygen supply.

Biomarkers Of Orthodontic Tooth Movement, Ellie Schwartz, Shubdeep Kaur, Mahsa Mortazavi, Marie M. Tolarova, Mirek Tolar

Excellence Day

Orthodontic tooth movement is made possible by remodeling of the alveolar bone process. Bone remodeling is carried out by cellular activities of osteoclasts, osteoblasts, and osteocytes. This in turn is regulated by a number of extracellular factors including growth factors, cytokines, chemokines, hormones and biomechanical force. This review is focused on chemical biomarkers characterizing orthodontic tooth movement.

Geometric Morphometric Shape Assessment Of Juvenile Mandibles, Tiffany Tran, Vicki Lo, Hee Soo Oh, Gary D. Richards

Excellence Day

OBJECTIVES: We explore three-dimensional data to delineate idiosyncratic and progressive growth variation in 6.0-8.0 year old mandibles (n=45).

Variation In And Assessment Of Inferior Alveolar Nerve Block Landmarks In Children And Adolescents, Soi Park, Younjin Lee, Younyoung Lee, Tiffany Tran, Gary D. Richards

Excellence Day

OBJECTIVES: In earlier work (Lambert et al., 2017) we demonstrated the efficacy of new landmarks for inferior alveolar nerve (IAN) block injections. While the latter study focused on adult morphology, the landmarks were shown to be effective in cases where the M³/₃ were present but unerupted. Based on these result a question arose as to their applicability of the landmarks to children and adolescents, given the known changes in mandibular foramen position during growth. Here we quantify the position of the mandibular foramen relative to standard landmarks during growth and assess the new landmarks applicability for IAN …

Root Analogue Implant Creation: Establishing Procedures For The General Dentist, Alicia Hazdovac, Sarah Osborne, Gary D. Richards

Excellence Day

The possibility of replacing damaged teeth with custom-made root analogue implants was initially suggested around 1969 and reintroduced by Lungren et al. in 1992. The latter authors created custom implants in titanium and reported good osteointegration and aesthetic results. Following this effort there has been an increasing focus on custom root analogue implants as a replacement for ‘screw-type’ implants. Given the availability of software to manipulate 3D image data and the rapid rise of 3D printing technology, the question arises as to whether a general dentist can produce their own implants. Here we test the feasibility of practitioners producing custom …

The Role Of Aryl Hydrocarbon Receptor (Ahr) Signaling Pathway In Oral Squamous Cell Carcinoma (Oscc): Preliminary Results., Renee Lee, Cui Xu, Leticia Ferreira, Ana Carolina Morandini, Erivan Ramos-Junior

Excellence Day

OBJECTIVES: A large number of experimental and clinical studies suggest that the origin of oral squamous cell carcinoma (OSCC) is linked to environmental carcinogenesis (tobacco, alcohol). Among these environmental factors, cigarette smoking is the most studied and has been associated with increased susceptibility to OSCC by activating signaling pathways responsible for cancer initiation and progression. Besides nicotine, cigarette smoke also contains aryl hydrocarbon receptor (AhR) agonists, such as dioxin and benzo(a)pyrene. Aberrant AhR expression and AhR pathway activation are involved in several types of cancer. However, the relationship between AhR pathway activation and oral cancer progression is still unclear.

Case Report: Use Of Non-Ridgid Connector, Veniamin Dronov

Excellence Day

Long span bridges have a tendency to experience harmful stress due to the increased surface area and of the restoration. These stresses can cause several problems including failure of the restoration or cause significant discomfort to the patient.

Treatment Planning: Facially Generated, Digitally Guided, Manually Fabricated Smile Design, Neal Atul Patel

Excellence Day

A clinical case presentation of a smile design that consists of 10 units of minimally invasive indirect restorations.

Changes In Airway Volume In Adult Patients Following Orthodontic Treatment With Premolar Extractions Versus Non-Extraction, Sunny Jisun Lee, Allison Kawata, Hayoung Michael Shin, David Chambers, Joorok Park, Heesoo Oh

Excellence Day

Recent concerns about the prevalence of obstructive sleep apnea (OSA) and its negative sequelae have led to investigations of how manipulation of the dentofacial complex may affect airway problems. CBCT can be used to measure airway dimensions of patients. Extraction of premolars is indicated as part of orthodontic treatment for patients who have severe crowding or protrusion of incisors. Some have suggested that the reduction in arch circumference after premolar extraction would lead to decreased airway volume, which may predispose a patient for sleep disordered breathing (SDB). The purpose of this study was to determine whether there is a significant …

Changes In Cephalometric Measurements In Adult Patients Following Orthodontic Treatment With Premolar Extractions Versus Non-Extraction, Byron Chou, David Dang, Adrienne Joy, David Chambers, Joorok Park, Heesoo Oh

Excellence Day

Extraction of premolars is indicated as part of orthodontic treatment for patients who have severe crowding or protrusion of incisors. CBCT can be used to locate cephalometric landmarks in 3D. The purpose of this study was to determine whether there are differences in sagittal, transverse, and vertical skeletal and dental dimensions for adult patients who were treated with premolar extractions in conjunction with orthodontic treatment compared to those who received orthodontic treatment without extractions.

Condylar Degeneration In Patients With Dental Open Bite Versus Skeletal Open Bite Utilizing Cbct, Alex Rauchle, Alston Trinh, Linda Phi, Brad Albertson, Joorok Park, Heesoo Oh

Excellence Day

Idiopathic condylar resorption (ICR) is a condition in which either one or both condyles undergo degeneration. Bilateral TMJ involvement presents as a clockwise rotation of the mandible in the posterior-inferior direction, resulting in an anterior open bite. The purpose of the study was to assess TMJ condylar degeneration in dental open bites compared to skeletal open bites.

Socio-Economic Factors That May Contribute To Etiology Of Orofacial Clefts., Shubdeep Kaur, Mahsa Mortazavi, Geethapriya Kumar, Marie M. Tolarova

Excellence Day

Association of socio-economic status (SES) with congenital anomalies and diseases has been studied for many years. Under the umbrella of SES are several factors and they vary in different parts of the world due to differences in climate, ethnicity, and culture.

The purpose of this systematic review was to determine associations between various risk factors related to SES and prevalence of orofacial clefts (OFC).

Distribution Of Malocclusions In Middle East Countries: A Systematic Review., Mahsa Mortazavi, Marie M. Tolarova

Excellence Day

High prevalence, multifactorial etiology and the effect on the esthetic, function and quality of life, make the malocclusions as a subject of debate for many years. Regarding the important role of malocclusion in treatment approaches, policy making in health organizations and understanding the etiology factors, this literature review was performed with the purpose of determining the prevalence and distribution of malocclusion in region of the Middle East.

Shear Bond Strength Of Nine Dual Cured Build-Up Materials And A Light-Curing Adhesive System On Dentin, Deepali Malla, Karen Schulze, Patrick Roetzer

Excellence Day

The purpose of this study was to measure the shear bond strength of nine different commercially available dual cured core build-up materials on human dentin in conjunction with a light curing adhesive system. The null hypothesis was that there is no statistical significant difference among the core build-up systems.

Longitudinal Cephalometric Study Of Untreated Subjects With Different Facial Types, Divya Vadlamudi, Shalaka Desai, Ambika Arun, Bhuvaneshwari Tatikonda, Shreya Penukonda, Apurva Dabak, Cindy Kim, Mai Nguyen, Heesoo Oh

Excellence Day

To examine the craniofacial morphological characteristics of different facial types based on vertical dysplasia in untreated subjects from the ages of 8 to 18.

Orofacial Clefts In The Middle Eastern Countries – A Systematic Review, Mahsa Mortazavi, Marie M. Tolarova

Excellence Day

The purpose of this study was to determine the prevalence of orofacial clefts (OFC) in the Middle East. Recent studies of etiology of OFC in populations of different countries characterized by a specific cultural, religious, or socioeconomic status revealed that different environmental and genetic factors may participate in their etiology.

Salivary Biomarkers For The Diagnosis And Monitoring Of Neurological Diseases, R. Farah, H. Haraty, Z. Salame, Y. Fares, David M. Ojcius, N. Said Sadier

All Dugoni School of Dentistry Faculty Articles

Current research efforts on neurological diseases are focused on identifying novel disease biomarkers to aid in diagnosis, provide accurate prognostic information and monitor disease progression. With advances in detection and quantification methods in genomics, proteomics and metabolomics, saliva has emerged as a good source of samples for detection of disease biomarkers. Obtaining a sample of saliva offers multiple advantages over the currently tested biological fluids as it is a non-invasive, painless and simple procedure that does not require expert training or harbour undesirable side effects for the patients. Here, we review the existing literature on salivary biomarkers and examine their …

19th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

Danger Signals, Inflammasomes, And The Intricate Intracellular Lives Of Chlamydiae, M. A. Pettengill, A. A. Sater, R. Coutinho-Silva, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

Chlamydiae are obligate intracellular bacterial pathogens, and as such are sensitive to alterations in the cellular physiology of their hosts. Chlamydial infections often cause pathologic consequences due to prolonged localized inflammation. Considerable advances have been made in the last few years regarding our understanding of how two key inflammation-associated signaling pathways influence the biology of

Purinergic Signaling During Porphyromonas Gingivalis Infection, C. Silva, A. C. Morandini, David M. Ojcius, R. Coutinho-Silva,

All Dugoni School of Dentistry Faculty Articles

Despite recent advances unraveling mechanisms of host–pathogen interactions in innate immunity, the participation of purinergic signaling in infection-driven inflammation remains an emerging research field with many unanswered questions. As one of the most-studied oral pathogens, Porphyromonas gingivalis is considered as a keystone pathogen with a central role in development of periodontal disease. This pathogen needs to evade immune-mediated defense mechanisms and tolerate inflammation in order to survive in the host. In this review, we summarize evidence showing that purinergic signaling modulates P. gingivalis survival and cellular immune responses, and discuss the role played by inflammasome activation and cell death during …

Alternative Functions For The Multifarious Inflammasome, J. Martel, H. C. Lai, Y. F. Ko, J. D. Young, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following injury. Recent studies indicate that inflammasome complex formation also participates in many other cellular and physiological processes beyond modulation of inflammation, such as autophagy, metabolism, eicosanoids production, and phagosome maturation.

17th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

16th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

15th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

14th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

13th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

12th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

11th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.

10th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.