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Full-Text Articles in Dentistry

Contact Point, Arthur A. Dugoni School Of Dentistry Aug 2011

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.


13th Annual Pacific Research Day Abstracts, University Of The Pacific May 2011

13th Annual Pacific Research Day Abstracts, University Of The Pacific

Excellence Day

No abstract provided.


Contact Point, Arthur A. Dugoni School Of Dentistry Apr 2011

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.


Periodontal Ligament And Gingival Fibroblasts Participate In The Production Of Tgf-Β, Interleukin (Il)-8 And Il-10, Ana Carolina Morandini, Carla Renata Sipert, Erivan Schnaider Ramos-Junior, Daniel Thomas Brozoski, Carlos Ferreira Santos Mar 2011

Periodontal Ligament And Gingival Fibroblasts Participate In The Production Of Tgf-Β, Interleukin (Il)-8 And Il-10, Ana Carolina Morandini, Carla Renata Sipert, Erivan Schnaider Ramos-Junior, Daniel Thomas Brozoski, Carlos Ferreira Santos

All Dugoni School of Dentistry Faculty Articles

The aim of this study was to quantify and compare the production of transforming growth factor beta (TGF-β), interleukin (IL)-8 and IL-10 by human cultured periodontal ligament and gingival fibroblasts both obtained from the same donors challenged with lipopolysaccharide (LPS) from Porphyromonas gingivalis. Fibroblasts were exposed to 0.1-10 µg/mL of LPS from P. gingivalis and after 24 h the supernatants were collected and analyzed by enzyme-linked immunosorbent assay (ELISA). TGF-β protein production was upregulated in a concentration-dependent manner, mainly in gingival fibroblasts, which was statistically significant when challenged by 10 µg/mL LPS. Additionally, at this concentration, gingival fibroblasts had almost …


D-4f, An Apoa-1 Mimetic, Decreases Airway Hyperresponsiveness, Inflammation, And Oxidative Stress In A Murine Model Of Asthma, S. D. Nandedkar, D. Weihrauch, H. Xu, Y. Shi, T. Feroah, W. Hutchins, D. A. Rickaby, Nejat Düzgüneş, C. A. Hillery, K. S. Konduri, K. A. Pritchard Mar 2011

D-4f, An Apoa-1 Mimetic, Decreases Airway Hyperresponsiveness, Inflammation, And Oxidative Stress In A Murine Model Of Asthma, S. D. Nandedkar, D. Weihrauch, H. Xu, Y. Shi, T. Feroah, W. Hutchins, D. A. Rickaby, Nejat Düzgüneş, C. A. Hillery, K. S. Konduri, K. A. Pritchard

All Dugoni School of Dentistry Faculty Articles

Asthma is characterized by oxidative stress and inflammation of the airways. Although proinflammatory lipids are involved in asthma, therapies targeting them remain lacking. Ac-DWFKAFYDKVAEKFKEAFNH2 (4F) is an apolipoprotein (apo)A-I mimetic that has been shown to preferentially bind oxidized lipids and improve HDL function. The objective of the present study was to determine the effects of 4F on oxidative stress, inflammation, and airway resistance in an established murine model of asthma. We show here that ovalbumin (OVA) -sensitization increased airway hyperresponsiveness, eosinophil recruitment, and collagen deposition in lungs of C57BL/6J mice by a mechanism that could be reduced by 4F. OVA …


Trident - January 2011, Dugoni School Of Dentistry Jan 2011

Trident - January 2011, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.