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Full-Text Articles in Dentistry

Orofacial Pain Overview: Getting Rid Of The Riddles, Andrew L. Young Dec 2016

Orofacial Pain Overview: Getting Rid Of The Riddles, Andrew L. Young

All Dugoni School of Dentistry Faculty Articles

While most pains that find their way to the dental office are dental in origin, some have less familiar roots: muscular, joint, neurological, headache, sinus or psychological. All of these roots can at times masquerade as a toothache. The purpose of this article is to alert the dentist to the select features of each root that distinguish it from the rest, resulting in efficient and appropriate treatment.


Danger Signals, Inflammasomes, And The Intricate Intracellular Lives Of Chlamydiae, M. A. Pettengill, A. A. Sater, R. Coutinho-Silva, David M. Ojcius Oct 2016

Danger Signals, Inflammasomes, And The Intricate Intracellular Lives Of Chlamydiae, M. A. Pettengill, A. A. Sater, R. Coutinho-Silva, David M. Ojcius

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Chlamydiae are obligate intracellular bacterial pathogens, and as such are sensitive to alterations in the cellular physiology of their hosts. Chlamydial infections often cause pathologic consequences due to prolonged localized inflammation. Considerable advances have been made in the last few years regarding our understanding of how two key inflammation-associated signaling pathways influence the biology of


Contact Point, Arthur A. Dugoni School Of Dentistry Aug 2016

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.


Trident - August 2016, Dugoni School Of Dentistry Aug 2016

Trident - August 2016, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.


Purinergic Signaling During Porphyromonas Gingivalis Infection, C. Silva, A. C. Morandini, David M. Ojcius, R. Coutinho-Silva, Aug 2016

Purinergic Signaling During Porphyromonas Gingivalis Infection, C. Silva, A. C. Morandini, David M. Ojcius, R. Coutinho-Silva,

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Despite recent advances unraveling mechanisms of host–pathogen interactions in innate immunity, the participation of purinergic signaling in infection-driven inflammation remains an emerging research field with many unanswered questions. As one of the most-studied oral pathogens, Porphyromonas gingivalis is considered as a keystone pathogen with a central role in development of periodontal disease. This pathogen needs to evade immune-mediated defense mechanisms and tolerate inflammation in order to survive in the host. In this review, we summarize evidence showing that purinergic signaling modulates P. gingivalis survival and cellular immune responses, and discuss the role played by inflammasome activation and cell death during …


Alternative Functions For The Multifarious Inflammasome, J. Martel, H. C. Lai, Y. F. Ko, J. D. Young, David M. Ojcius Jun 2016

Alternative Functions For The Multifarious Inflammasome, J. Martel, H. C. Lai, Y. F. Ko, J. D. Young, David M. Ojcius

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The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following injury. Recent studies indicate that inflammasome complex formation also participates in many other cellular and physiological processes beyond modulation of inflammation, such as autophagy, metabolism, eicosanoids production, and phagosome maturation.


Neurotrophic Factors: Promising Candidates In Tissue Regeneration, Nan (Tori) Xiao May 2016

Neurotrophic Factors: Promising Candidates In Tissue Regeneration, Nan (Tori) Xiao

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No abstract provided.


Advances In Endodontics: Potential Applications In Clinical Practice., Anil Kishen, Ove A. Peters, Matthias Zehnder, Anibal R. Diogenes, Madhu K. Nair May 2016

Advances In Endodontics: Potential Applications In Clinical Practice., Anil Kishen, Ove A. Peters, Matthias Zehnder, Anibal R. Diogenes, Madhu K. Nair

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Contemporary endodontics has seen an unprecedented advance in technology and materials. This article aimed to review some of the challenges and advances in the following sections: (1) endodontic imaging, (2) root canal preparation, (3) root canal disinfection, (4) root canal filling, and (4) regenerative endodontic procedures (REPs). Jointly, these advances are aimed at improving the state of the art and science of root canal treatment.


Educational Outcomes Of Small-Group Discussion Versus Traditional Lecture Format In Dental Students' Learning And Skills Acquisition., Ana Arias, Raymond Scott, Ove A. Peters, Elizabeth Mcclain, Alan H. Gluskin Apr 2016

Educational Outcomes Of Small-Group Discussion Versus Traditional Lecture Format In Dental Students' Learning And Skills Acquisition., Ana Arias, Raymond Scott, Ove A. Peters, Elizabeth Mcclain, Alan H. Gluskin

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The aim of this prospective quantitative study was to compare the effect of different instructional formats on dental students' skills and knowledge acquisition for access cavity preparation. All first-year dental students were invited to participate in this study conducted during the four consecutive two-week endodontic rotation courses at the University of the Pacific Arthur A. Dugoni School of Dentistry in spring semester 2015. Four alphabetically distributed intact groups of students were randomly allocated to two groups (n=70 each) that participated in either small-group discussion or a traditional lecture on access preparation. The first outcome measure was skill acquisition, measured by …


Contact Point, Arthur A. Dugoni School Of Dentistry Apr 2016

Contact Point, Arthur A. Dugoni School Of Dentistry

Contact Point

No abstract provided.


Trident - February 2016, Dugoni School Of Dentistry Feb 2016

Trident - February 2016, Dugoni School Of Dentistry

Trident

The newsletter of the Pacific Orthodontic Alumni Chapter at University of the Pacific, Arthur A. Dugoni School of Dentistry.


Biological Markers For Pulpal Inflammation: A Systematic Review., Dan-Krister Rechenberg, Johnah C. Galicia, Ove A. Peters Jan 2016

Biological Markers For Pulpal Inflammation: A Systematic Review., Dan-Krister Rechenberg, Johnah C. Galicia, Ove A. Peters

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BACKGROUND AND OBJECTIVE: Pulpitis is mainly caused by an opportunistic infection of the pulp space with commensal oral microorganisms. Depending on the state of inflammation, different treatment regimes are currently advocated. Predictable vital pulp therapy depends on accurate determination of the pulpal status that will allow repair to occur. The role of several players of the host response in pulpitis is well documented: cytokines, proteases, inflammatory mediators, growth factors, antimicrobial peptides and others contribute to pulpal defense mechanisms; these factors may serve as biomarkers that indicate the status of the pulp. Therefore, the aim of this systematic review was to …


Interrelationships In The Variability Of Root Canal Anatomy Among The Permanent Teeth: A Full-Mouth Approach By Cone-Beam Ct., Paul Monsarrat, Bertrand Arcaute, Ove A. Peters, Elisabeth Maury, Norbert Telmon, Marie Georgelin-Gurgel, Delphine Maret Jan 2016

Interrelationships In The Variability Of Root Canal Anatomy Among The Permanent Teeth: A Full-Mouth Approach By Cone-Beam Ct., Paul Monsarrat, Bertrand Arcaute, Ove A. Peters, Elisabeth Maury, Norbert Telmon, Marie Georgelin-Gurgel, Delphine Maret

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OBJECTIVES: In endodontic practice, clinicians should be aware of possible root canal anatomic variations. The aim of this study was to assess using CBCT acquisitions regarding whether one root canal anatomy of a tooth is associated with a specific anatomy of another tooth.

METHODS: A total of 106 CBCT acquisitions were obtained using a CBCT scanner with 200μm voxel size. Numbers of roots and canals of the entire dentition were described. Bivariate analyses and logistic regressions were conducted to explore root canal anatomy on one tooth according to age, gender, jaw, side and the others teeth. Multiple correspondence analysis (MCA) …