Pharmacology, Toxicology and Environmental Health Commons^™

Comparison Of The Management Between Independent And Chain Drugstores In Municipal Area, Muang District, Chiang Mai Province(การเปรียบเทียบการบริหารจัดการร้านขายยา ระหว..., Chupen Viboonsunti, Poobate Keawpinta, Montree Sornbial, Eakarin Chadchuchaitip

The Thai Journal of Pharmaceutical Sciences

The objective of this study was to compare the management of independent drugstores and chain drugstores in municipal area, Muang District, Chiang Mai Province. Interviews of thirty drugstores consisting twenty independent drugstores and ten chain drugst...

Discrepancies Of Patient Package Inserts Of 24 Brand Name Oral Contraceptive Pill Products In Thailand(ความไม่สอดคล้องกันของเอกสารกำกับยาสำหรับผู้ใช้ยารั..., Sumamas Rabeab-Oat, Supawadee Petch-Phrom, Jurapom Pongwecharak

The Thai Journal of Pharmaceutical Sciences

The study was to examine and compare drug information provided in package inserts of oral contraceptive products marketed in Thailand. List of the products currently marketed in Thailand was obtained from Drug Control Division, Food and Drug Administrati...

Antiviral And Anticancer Activities Of Stemona Collinsae(ฤทธิ์ต้านไวรัส และฤทธิ์ต้านมะเร็งของ Stemona Collinsae), Pannarat Akanitapichat, Pajaree Tongngok, Aree Wangmaneerat, Bungom Sripanidkulchai

The Thai Journal of Pharmaceutical Sciences

The roots of Stemona (Stemonaceae) have long been used traditionally for the treatment of respiratory diseases, enteric helminthes and as insecticides. In the present study, the dichloromethane-methanol (DCM-M, :1), 95% ethanol and aqueous extracts of St...

Terpenoid Constituents From Leaves And Cell Cultures Of Artemisia Vulgaris Var. Indica And Application Of Biotechnological Techniques To Increase Davanone Level(สารกลุ่มเทอร์ปินอยด์จากใบและเซล..., Supawan Bunrathep, Thanapat Songsak, Nijsiri Ruangrungsi

The Thai Journal of Pharmaceutical Sciences

Sterilised leaf expiants of Artemisia vulgaris var. indica were placed on semisolid basal MS media, containing 1 mg/1 of 2 ,4 -dichlorophenoxyacetic acid and 0.1 mg/1 of kinetin in order to initiate callus cultures. Cell suspension cultures were then ini...

Dna Fingerprinting Of Medicinally Used Derris Species By Rapd Molecular Markers(ลายพิมพ์ดีเอ็นเอของพืชสมุนไพรสกุล Derris โดยใช้เครื่องหมายโมเลก..., Suchada Sukrong, Thatree Phadungcharoen, Nijsiri Ruangrungsi

The Thai Journal of Pharmaceutical Sciences

DNA fingerprinting of five medicinal used Derris species, D. scandens, D. elliptica, D. malaccensis, D. trifoliata, and D. reticulata, was studied using random amplified polymorphic DNA (RAPD) technique. In medicinal plant market, herbal drugs were often...

In Vitro Inhibitory Effect Of Turmeric Extract From Curcuma Longa On Shrimp Pathogenic Vibrios(ผลของสารสกัดขมิ้นชันต่อการยับยั้งการเจริญของเชื้อวิบร..., Pomchai Rojsitthisak, Yanin Limpanon, Nutchanart Thipmongkolsilp, Bang-On Kongtong, Janenuj Wongtavatchai

The Thai Journal of Pharmaceutical Sciences

The commercially available turmeric extract from Curcuma longa L. was standardized and evaluated for antibacterial activity against shrimp pathogenic vibrios. High-performance liquid chromatographic determination of the extract revealed 99.42% of the tot...

Analytical And Synthetic Methods For Anatoxins., Janet Crowley

Theses

This thesis is focused on the potent cyanobacterial neurotoxins anatoxin-a (AN), its methyl analogue homoanatoxin-a (HMAN) and their non-toxic dihydro- and epoxydegradation products. In commencing the investigation into this area a literature review was performed in order to identify areas where more research and method development was required (Chapter 1). The review highlighted the fact that although a number of analytical methods had been developed for the analysis of AN, there were few methods for the determination of its potent homologue HMAN and their non-toxic degradation products. As these neurotoxins degrade quickly it is important to monitor their degradation products, …

The Role Of Peroxidases In The Development Of Plants And Their Responses To Abiotic Stresses., Deborah Vicuna

Doctoral

Peroxidases and its effects on plants were analysed. Peroxidases are involved in many physiological processes in plants, involving responses to biotic and abiotic stresses and the biosynthesis of lignin. Liglin is a polymer responsible for rendering the plant stronger and more rigid and also making the cell walls hydrophobic. Peroxidases are involved in the polymerization of the precursors of lignin. They are also involved in the scavenging of Reactive Oxygen Species (ROS), which are partially reduced forms of atmospheric oxygen, highly reactive, and capable of causing oxidative damage to the cell. Peroxidases can be a source of hydrogen peroxide (H2O2) …

Preparation Of Fast Release Indomethacin Solid Dispersion By Spray- Drying Using Lactose As Water-Soluble Carrier(การเตรียมอินโดเมธาชินโซลิดดิสเพอร์ชันชนิดปลดปล..., Pienkit Dangprasirt, Vasinee Limwong

The Thai Journal of Pharmaceutical Sciences

Solid dispersions of a poorly water-soluble drug, indomethacin (ID), in a water-soluble carrier, lactose, were prepared by coprecipitation method using a spray dryer. Dissolution tests were performed on the prepared ID and 1-2 IDdactose solid dispersion ...

Exploring Marine Biotoxins Using Analytical Techniques Based On Mass Spectrometry, Mónica Fernández Amandi

Theses

The impact of phycotoxins on human and animal health is of important concern for worldwide authorities and the scientific community. Domoic acid (DA) is a neurotoxin produced by phytoplankton {Pseudonitzchia spp.). It enters the food chain through the consumption of shellfish that feed on toxic diatoms. DA has been responsible for several outbreaks affecting humans and animals all around the world. Yessotoxin (YTX) is produced by dinoflagellate species {Protoceratiuni reticulatum) which are globally distributed. Its toxicity is low when ingested orally. However, the co-extraction of YTX with diarrhetic shellfish poisoning (DSP) toxins, derives false positives when the mouse bioassay is …

Access To Medicinal Plant Resources In Vietnam - A Fair And Equitable Sharing Of Benefits(การเข้าถึงทรัพยากรพืชสมุนไพรในเวียดนาม-การนำไปใช้ประโยช..., Tran Cong Khanh

The Thai Journal of Pharmaceutical Sciences

Abstract There are in Vietnam 3,830 registered medicinal plant species, apart from numerous ethno- medicinal plants which have not been sufficiently inventoried and documented. Traditional knowledge in using animals and plants for treatment and health ca...

Anti-Heroes Simplex Virus Type 1 Activity Of Local Northeastern Plants(ฤทธิ์ต้าน Herpes Simplex Virus Type 1 ของพืชผักท้องถิ่นในภาคอีสาน), Pannarat Akanitapichat, Aree Wangmaneerat, Nongnit Teerawatanasuk

The Thai Journal of Pharmaceutical Sciences

Eighty extracts sequentially percolated from forty local northeastern plants with dichloromethane- methanol (DCM'M, 1:1) and methanol were evaluated for in vitro anti-herpes simplex virus type 1 (HSV-1) activity. Using plaque reduction assay, 31 extracts...

Evaluation Of Anticonvulsant Activity Of Valproyl Hydroxamic Acid(การประเมินฤทธิ์ต้านชักของกรดวาลโปรอิลไฮดรอกซามิก), Boonyong Tantisira, Mayuree H., Chamnan Patarapanich, Nalinrat Thongsathean

The Thai Journal of Pharmaceutical Sciences

Valproyl hydroxamic acid (VHA) is a novel derivative of valpromide, a pro-drug of valproic acid (VPA). Preliminary screening of VHA revealed its anticonvulsant activity against electrically induced convulsion in mice. Additional evaluation of its efficac...

แก้ไข, N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.

Bioprospecting, Philip A. Reed

STEMPS Faculty Publications

The article discusses that the product applications of bioprospecting are almost limitless. This area of biotechnology has been labeled bioprospecting, and it is a practice that is creating worldwide controversy. Defined simply, bioprospecting is "scientific research that looks for a useful application, process, or product in nature." However, as with most biotechnologies, the definition does not address the complexities of bioprospecting. Archeologists are finding that some biotechnologies, such as the use of herbs for medicine and the use of fermentation and yeast in food products, date back 5,000 to 10,000 years (De Miranda, 2004). The four main categories of biotechnologies …

An Inventory Of Rangelands In Part Of The Broome Shire, Western Australia, W E. Cotching

Technical Bulletins

The inventory of rangelands in part of the Broome Shire in Western Australia was undertaken by DAFWA between 1989 and 1990. It describes and maps the natural resources of the region’s pastoral leasehold land. This survey report provides a baseline record of the existence and condition of the natural area’s resources, to assist with the planning and implementation of land management practices. The report identified and described the condition of soils, landforms, vegetation, habitat, ecosystems, and declared plants and animals. It also assessed the impact of pastoralism and made land management recommendations. The survey of part of the Broome Shire …

Atrazine Runoff In The Blue River Basin: Geomorphology, Rainfall, And Agronomic Practices, Kundan Dhakal

Department of Agronomy and Horticulture: Dissertations, Theses, and Student Research

Atrazine concentrations in the Big Blue River Basin (BRB) in Nebraska and Kansas periodically exceed the U.S. EPA Maximum Contaminant Level (MCL) of 3 µg L^-1. The present study is focused on watershed variables influencing surface runoff of atrazine. The assessment includes the impact of corn and sorghum planting progress (indicating atrazine application), rainfall, antecedent soil water content, and soil restrictive layer on stream-measured weekly atrazine load in independent BRB subwatersheds for 1997 - 2004. Maximum atrazine loading occurred after most of the corn had been planted but during sorghum planting from mid-May to early June, immediately following …

Respiratory Symptoms In Relation To Residential Coal Burning And Environmental Tobacco Smoke Among Early Adolescents In Wuhan, China: A Cross-Sectional Study, C. Anderson Johnson, Jiang Xia, Päivi M. Salo, Yan Li, Grace E. Kissling, Edward L. Avol, Chunhong Liu, Stephanie J. London

CGU Faculty Publications and Research

Background

Cigarette smoking and coal burning are the primary sources of indoor air pollution in Chinese households. However, effects of these exposures on Chinese children's respiratory health are not well characterized.

Methods

Seventh grade students (N = 5051) from 22 randomly selected schools in the greater metropolitan area of Wuhan, China, completed an in-class self-administered questionnaire on their respiratory health and home environment.

Results

Coal burning for cooking and/or heating increased odds of wheezing with colds [odds ratio (OR) = 1.57, 95% confidence interval (CI): 1.07–2.29] and without colds (OR = 1.44, 95% CI: 1.05–1.97). For smoking in the home, …

Indivisible Injury Negligence And Nuisance Cases –Proving Causation Among Multiple-Source Polluters: A State-By-State Survey Of The Law For New England, And A Proposal For A New Causation Framework, Paul Homer

The University of New Hampshire Law Review

[Excerpt] "The skies, soil, and water of every state are polluted every day. Whether the pollutants enter the atmos phere from coal plants or the water-ways from large farms, materials a bnormal to the “natural” environment are regularly emitted by a variety of sources over wide regions of the nation. To some extent, such emissions are normal and acceptable activities in modern society."

Layer-By-Layer Self -Assembly For Enzyme And Dna Encapsulation And Delivery, Amish Patel

Doctoral Dissertations

Thin wall microcapsules were formed via Layer-by-Layer Self-Assembly of alternate adsorption of oppositely charged polyelectrolyte on microcores. After the core dissolution, empty polymeric shells with 20–25 nm thick walls were obtained. These microcapsules were loaded with Myoglobin, Hemoglobin and Glucose Oxidase by opening capsule pores at low pH and closing them at higher pH. The native structure of the enzyme was not affected due to different treatments. Biocompatible nanoshells were also prepared for encasing DNA. Using the same Layer-by-Layer Self-Assembly approach nanoparticle were constructed containing DNA as one of the layers. The nanoparticles of different architecture were used to deliver …

Regulatory Mechanisms Of Uterine Artery Contractility : Effect Of Pregnancy, Daliao Xiao

Loma Linda University Electronic Theses, Dissertations & Projects

Regulation of uterine blood flow during pregnancy is important not only for the growth and survival of the fetus but also for cardiovascular well-being of the mother. Pregnancy is associated with a significant decrease in uterine artery vascular tone and a dramatic increase in uterine blood flow. Previous studies have been focused on adaptation of the endothelium to pregnancy and indicated that increased NO sythesis/release plays an important role in vasodilation of the uterine artery in pregnancy. However, little is known about the adaptation of contractile mechanisms of the uterine artery to pregnancy. The central hypothesis of the proposed studies …

Hk-2 Cells As A Human Model Of Glucuronide Transport, Eliza E. Robertson

Theses, Dissertations and Capstones

Glucuronidation is primarily a pathway of detoxification in most species, but many glucuronide conjugates are associated with toxicity. Numerous drugs are excreted in the urine as glucuronide conjugates. Being organic anions, it is likely that glucuronides are secreted into the urine by organic anion transporters found in renal proximal tubule cells (PTCs). Some drugs that are metabolized by glucuronidation have been shown to cause renal toxicity, yet little is known about the renal handling of glucuronide conjugates. It is hypothesized that glucuronides are transported into renal PTCs by an organic anion transporter (OAT) on the basolateral membrane of the cell. …

Pharmacist Compensation Survey In Thailand(การสำรวจค่าตอบแทนของเภสัชกรในประเทศไทย), Surachat Ngorsuraches, Banjong Chaibu

The Thai Journal of Pharmaceutical Sciences

The objective of this study was to survey pharmacist compensation in Thailand. The pharmacists’ compensation from both full-time and part-time works was examined. The study was cross-sectional descriptive design and data were collected by mailed survey...

Antimicrobial Utilization In Nosocomial-Infected Patients At Ratchaburi Hospital(การใช้ยาต้านจุลชีพในผู้ป่วยโรคติดเชื้อในโรงพยาบาลที่โรงพย..., Sarinee Krittiyanunt, Wundee Khumyoung

The Thai Journal of Pharmaceutical Sciences

The objectives of this descriptive study were to study the antimicrobial utilization, type and susceptibility of pathogens, and drug therapy problems (DTPs) in nosocomia-infected patients at Ratchaburi hospital from August 1st to December 31st, 2002. Two...

Predictors Of General Knowledge And Attitudes In Thai Diabetic Patients(ป้จจัยทำนายความรู้ทั่วไปและทัศนคติของผู้ป่วยเบาหวานคนไทย), Supakit Wongwiwatthananukit, Sarinee Krittiyanunt, Thongkum Sunthomthepvarakul, Aunchalee Wannapinyo

The Thai Journal of Pharmaceutical Sciences

The aim of this cross-sectional survey study was to determine the relationships between patients’ demographic characteristics and the level of knowledge and attitudes toward diabetes. A total of 811 diabetes patients participated and were assessed duri...

Key Word Index, Author Index(ดรรชนีกุญแจคำ,ดรรชนีผู้แต่ง), N/A

The Thai Journal of Pharmaceutical Sciences

No abstract provided.

Neuroscience Beyond 2005, ภาวิซ ทองโรจน์

The Thai Journal of Pharmaceutical Sciences

No abstract provided.

Drugs And Brain Plasticity(ยาและความยืดหยุ่นของสมอง), Jintana Sattayasai

The Thai Journal of Pharmaceutical Sciences

Brain plasticity is emerging as a fundamental and critical mechanism of neuronal function, which allows the brain to receive information and make the appropriate adaptive responses to subsequent related stimuli. The understanding of the mechanisms at mol...

งานวิจัยประสาทวิทยาศาสตร์ไนคณะเภสัชศาสตร์ จุฬาลงกรณ์มหาวิทยาลัย, มยุรี ตันติสิระ

The Thai Journal of Pharmaceutical Sciences

No abstract provided.

Antimutagenicity Of Different Lyophilized Ripe Bananas On Mutagens In Ames Test And Somatic Mutation And Recombination Test(ฤทธิ์ต้านสารก่อกลายพันธุ์ของผงกล้วยต่างชนิด..., Kalyarat Kruawan, Kaew Kangsadalampai, Komchanok Limpichaisopon

The Thai Journal of Pharmaceutical Sciences

The Ames test was employed to indicate the inhibitory effects of lyophilized powders prepared from three varieties of ripe bananas, namely, Klouy Nam Wa (Pisang Awak or Musa ABB group) Klouy Hom (Gros Michael or Musa AAA group), and Klouy Khai (Pisang Ma...