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Articles 1 - 30 of 56

Full-Text Articles in Pharmacology, Toxicology and Environmental Health

Lead Bioaccessibility And Commonly Measured Soil Characteristics (Detroit, Mi, Usa) Phase Ii, Conor T. Gowan, Sabrina R. Good, Allison R. Harris, Patrick Crouch, Shawn P. Mcelmurry Jan 2025

Lead Bioaccessibility And Commonly Measured Soil Characteristics (Detroit, Mi, Usa) Phase Ii, Conor T. Gowan, Sabrina R. Good, Allison R. Harris, Patrick Crouch, Shawn P. Mcelmurry

Open Data at Wayne State

Urban soil contaminated with anthropogenic sources of Pb is a major contributor to child Pb exposure. To assess the Pb risk in urban areas, composite samples were collected from 142 voluntary privately owned 142 residential parcels in Detroit, Hamtramck, and Highland Park, Michigan. Samples were collected at two time periods, before and after treatment applied for those denoted as treatment sites. Samples were collected from areas covered with turf grass on the parcels from the front, middle and rear sections. Soils were collected with a bulb planter at approximately 10cm depth and were cleaned with a tap water-Liquinox detergent solution …


Gene Expression Analysis Reveals Dysregulation In Traumatic Brain Injury Leading To Tauopathy, Kristina M. Tosi Jul 2024

Gene Expression Analysis Reveals Dysregulation In Traumatic Brain Injury Leading To Tauopathy, Kristina M. Tosi

USF Tampa Graduate Theses and Dissertations

Traumatic Brain Injury (TBI) causes a cascade of detrimental events within neurons, contributing to a host of neurological diseases relating to dementia. In this study we have performed a meta-analysis comparing differentially expressed genes (DEG) in specific cell types such as neurons and microglia revealing inflammation as a common driver of neurological deficiencies post TBI. Inflammation and hypoxia are well characterized features of TBI; however, the molecular mechanisms causing tau hyperphosphorylation by tauopathy associated genes (TAG) post-TBI are currently poorly understood. Furthermore, there are limited in-vitro neuroinflammatory models that mimic primary and secondary TBI. We hypothesize that inducing hypoxia and …


Data For: "Polyethylene Polymer Type And Soil Properties Determine Impacts Of Microplastic Pollution On Arugula Growth", Noah P. Walsh, Ella Beaghen, Abigail Kane, Leilani M. Santodomingo, Daniel Watson, Christina S. Baer Jan 2024

Data For: "Polyethylene Polymer Type And Soil Properties Determine Impacts Of Microplastic Pollution On Arugula Growth", Noah P. Walsh, Ella Beaghen, Abigail Kane, Leilani M. Santodomingo, Daniel Watson, Christina S. Baer

First-Year Research Immersion (FRI) Scholarship

From the manuscript abstract:

While microplastics have become a novel pollutant of concern, few studies have directly compared different polymers’ effects on plants. We investigated the effects of high-density (HDPE) and low-density (LDPE) polyethylene on arugula growth. We hypothesized that polyethylene microplastics would inhibit growth and that LDPE would have a greater effect than HDPE due to its branched structure and lower density. We grew arugula (Eruca vesicaria) in plain soil or soil mixed with HDPE or LDPE microplastics. To determine if microplastic effects are dependent on soil quality, we used two kinds of fresh soil and reused one type …


Lead Bioaccessibility And Commonly Measured Soil Characteristics (Detroit, Mi, Usa) – Phase 1, Sabrina R. Good, Allison R. Harris, Patrick Crouch, Conor T. Gowan, William D. Shuster, Shawn P. Mcelmurry Jan 2024

Lead Bioaccessibility And Commonly Measured Soil Characteristics (Detroit, Mi, Usa) – Phase 1, Sabrina R. Good, Allison R. Harris, Patrick Crouch, Conor T. Gowan, William D. Shuster, Shawn P. Mcelmurry

Open Data at Wayne State

Contaminated urban soil is one of the major contributors to child Pb exposure. To gain a better understanding of Pb risk in urban areas, composite samples were collected from 142 residential, privately owned, parcels in Detroit, Hamtramck, and Highland Park, Michigan, with approval from the property owners. The proximity of soil sampling and former smelter locations were also reported. Sample were collected from areas covered with turf grass. Four samples were collected, one from each cardinal direction (north, south, east, and west), 20 cm from an aluminum tent stake driven into the center of the sampling site. Soils were collected …


Bazedoxifene, Parth M. Raina, Mayur Parmar Jan 2023

Bazedoxifene, Parth M. Raina, Mayur Parmar

HPD Articles

No abstract provided.


Romosozumab, Kristina Krupa, Mayur Parmar, Linda F. Delo Jan 2023

Romosozumab, Kristina Krupa, Mayur Parmar, Linda F. Delo

HPD Articles

No abstract provided.


Abaloparatide, Miis Akel, Mayur Parmar Jan 2023

Abaloparatide, Miis Akel, Mayur Parmar

HPD Articles

No abstract provided.


Dataset For Manuscript: Comparing Performance Of Spectral Image Analysis Approaches For Detection Of Cellular Signals In Time-Lapse Hyperspectral Imaging Fluorescence Excitation-Scanning Microscopy, Silas J. Leavesley Jan 2023

Dataset For Manuscript: Comparing Performance Of Spectral Image Analysis Approaches For Detection Of Cellular Signals In Time-Lapse Hyperspectral Imaging Fluorescence Excitation-Scanning Microscopy, Silas J. Leavesley

BioImaging and BioSystems Research

The dataset contains raw and processed hyperspectral timelapse image data that are described in the manuscript:

Parker, M., Annamdevula, N. S., Pleshinger, D., Ijaz, Z., Jalkh, J., Penn, R., Deshpande, D., Rich, T. C. & Leavesley, S. J. Comparing Performance of Spectral Image Analysis Approaches for Detection of Cellular Signals in Time-Lapse Hyperspectral Imaging Fluorescence Excitation-Scanning Microscopy. Bioengineering 10, 642 (2023).


Golimumab, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2022

Golimumab, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Small Interfering Rna (Sirna)-Based Therapy, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar Jan 2022

Small Interfering Rna (Sirna)-Based Therapy, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.


Sodium-Glucose Transport Protein 2 (Sglt2) Inhibitors, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar Jan 2022

Sodium-Glucose Transport Protein 2 (Sglt2) Inhibitors, Inderbir S. Padda, Arun U. Mahtani, Mayur S. Parmar

HPD Articles

No abstract provided.


Biosimilars Use In Medicine For Inflammatory Diseases, Inderbir S. Padda, Rajat Bhatt, Obaid Rehman, Mayur S. Parmar Jan 2021

Biosimilars Use In Medicine For Inflammatory Diseases, Inderbir S. Padda, Rajat Bhatt, Obaid Rehman, Mayur S. Parmar

HPD Articles

No abstract provided.


Upadacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Upadacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Tofacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Tofacitinib, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Pegloticase, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Pegloticase, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Apremilast, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar Jan 2021

Apremilast, Inderbir S. Padda, Rajat Bhatt, Mayur S. Parmar

HPD Articles

No abstract provided.


Lenvatinib, Inderbir S. Padda, Mayur S. Parmar Jan 2021

Lenvatinib, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.


Covid (Sars-Cov-2) Vaccine, Inderbir S. Padda, Mayur S. Parmar Jan 2021

Covid (Sars-Cov-2) Vaccine, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.


Aducanumab, Inderbir S. Padda, Mayur S. Parmar Jan 2021

Aducanumab, Inderbir S. Padda, Mayur S. Parmar

HPD Articles

No abstract provided.


Obeticholic Acid, Kristina Krupa, Vera Hapshy, Hiep Nguyen, Mayur S. Parmar Jan 2021

Obeticholic Acid, Kristina Krupa, Vera Hapshy, Hiep Nguyen, Mayur S. Parmar

HPD Articles

No abstract provided.


Data From: Consumption Of The Total Western Diet Promotes Colitis And Inflammation-Associated Colorectal Cancer In Mice, Abby D. Benninghoff Feb 2020

Data From: Consumption Of The Total Western Diet Promotes Colitis And Inflammation-Associated Colorectal Cancer In Mice, Abby D. Benninghoff

Browse all Datasets

Gene expression data for colon tissues obtained prior to, during, and after onset of colitis in mice fed either a standard or Western type diet.

File 1: probe annotations.

File 2: nSolver differential expression analysis results.

File 3: Gene set analysis

File 4: nSolver pathway scores

File 5: STRING-db networks and clusters

File 6: Metascape ontology results

File 7: nSolver cell type profiling scores


Omega-3 Fatty Acids, Kristina Krupa, Kristina Fritz, Mayur S. Parmar Jan 2020

Omega-3 Fatty Acids, Kristina Krupa, Kristina Fritz, Mayur S. Parmar

HPD Articles

No abstract provided.


Iron Dextran, Sebastiano Failla, Mayur S. Parmar Jan 2020

Iron Dextran, Sebastiano Failla, Mayur S. Parmar

HPD Articles

No abstract provided.


Calcium Carbonate, Kristina Fritz, Katherine Taylor, Mayur S. Parmar Jan 2020

Calcium Carbonate, Kristina Fritz, Katherine Taylor, Mayur S. Parmar

HPD Articles

No abstract provided.


Famciclovir, Jennifer R. Semaan, Mayur S. Parmar Jan 2020

Famciclovir, Jennifer R. Semaan, Mayur S. Parmar

HPD Articles

No abstract provided.


Doxycycline Hyclate, Reema S. Patel, Mayur S. Parmar Jan 2020

Doxycycline Hyclate, Reema S. Patel, Mayur S. Parmar

HPD Articles

No abstract provided.


Pramipexole, Raman Singh, Mayur S. Parmar Jan 2020

Pramipexole, Raman Singh, Mayur S. Parmar

HPD Articles

No abstract provided.


Teriparatide, Hacen Vall, Mayur S. Parmar Jan 2020

Teriparatide, Hacen Vall, Mayur S. Parmar

HPD Articles

No abstract provided.


Human Papilloma Virus Vaccine, Lucia Soca Gallego, Alvio Dominguez, Mayur S. Parmar Jan 2020

Human Papilloma Virus Vaccine, Lucia Soca Gallego, Alvio Dominguez, Mayur S. Parmar

HPD Articles

No abstract provided.


Reserpine, Michelle Cheung, Mayur S. Parmar Jan 2020

Reserpine, Michelle Cheung, Mayur S. Parmar

HPD Articles

No abstract provided.