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Articles 7501 - 7530 of 37178
Full-Text Articles in Electrical and Computer Engineering
Organizing Committee: Reach To Space Conference On Space Commercialization: A Celebration Of 50 Years In Space, D. Flournoy
Organizing Committee: Reach To Space Conference On Space Commercialization: A Celebration Of 50 Years In Space, D. Flournoy
Online Journal of Space Communication
Michael Beavin, Department of Commerce
Robert Bell, SSPI
Tamara Bond, SSPI
David Bross, Hannover Fairs Corporartion
Dean Henry Burdg, Auburn University
David Cavossa, Arrowhead Global Solutions
Scott Chase, Access Intelligence
Leonard David, Space.com
Kenneth Davidian, NASA
Don Flournoy, Ohio University
Tara Giunta, Paul Hastings Janofsky & Walker LLC
Ray Hamilton, Auburn University
Douglas Heydon, Consultant
Susan Irwin, Irwin Communications
Hussein Jirdah, Universities Space Research Association
Randy Johnson, Auburn University
David Logsdon, US Chamber of Commerce, Space Enterprise Project
Andrea Maleter, Futron Corporation
Ted Mallory, Astar Air Cargo
Joseph Pelton, George Washington University
Art Poland, George Mason University
Lon Rains, Space …
Sponsors: Reach To Space Conference On Space Commercialization: A Celebration Of 50 Years In Space, D. Flournoy
Sponsors: Reach To Space Conference On Space Commercialization: A Celebration Of 50 Years In Space, D. Flournoy
Online Journal of Space Communication
Sponsors of the Reach to Space Conference on Space Commercialization: A Celebration of 50 Years in Space
Speaker Biographies: Reach To Space Conference On Space Commercialization: A Celebration Of 50 Years In Space, D. Flournoy
Speaker Biographies: Reach To Space Conference On Space Commercialization: A Celebration Of 50 Years In Space, D. Flournoy
Online Journal of Space Communication
Speaker Biographies: Reach to Space Conference on Space Commercialization: A Celebration of 50 Years in Space
Edward D. Horowitz
Phillip Spector
John Mattingly
Robert Bell
Joseph N. Pelton
Courtney Stadd
Gregg Maryniak
J. Steven Newman
Lon Rains
Don M. Flournoy
John Ordway
Conference Program, D. Flournoy
Conference Program, D. Flournoy
Online Journal of Space Communication
CONFERENCE ON SPACE COMMERCIALIZATION
CELEBRATION OF 50 YEARS IN SPACE
AND LOOKING TO THE FUTURE
CONFERENCE PROGRAM
Monday, November 12, 2007
Recent Advances And Trends Of Predictive Maintenance From Data-Driven Machine Prognostics Perspective, Yuxin Wen, Md. Fashiar Rahman, Honglun Xu, Tzu-Liang Bill Tseng
Recent Advances And Trends Of Predictive Maintenance From Data-Driven Machine Prognostics Perspective, Yuxin Wen, Md. Fashiar Rahman, Honglun Xu, Tzu-Liang Bill Tseng
Engineering Faculty Articles and Research
In the Engineering discipline, prognostics play an essential role in improving system safety, reliability and enabling predictive maintenance decision-making. Due to the adoption of emerging sensing techniques and big data analytics tools, data-driven prognostic approaches are gaining popularity. This paper aims to deliver an extensive review of recent advances and trends of data-driven machine prognostics, with a focus on their applications in practice. The primary purpose of this review is to categorize existing literature and report the latest research progress and directions to support researchers and practitioners in acquiring a clear comprehension of the subject area. This paper first summarizes …
Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings
Using Bibliometrics To Evaluate Outcomes And Influence Of Translational Biomedical Research Centers, Kristine M. Bragg, Gwen C. Marchand, Jonathan C. Hilpert, Jeffrey L. Cummings
Educational Psychology, Leadership, and Higher Education Faculty Research
Introduction. Federal grant funding to support infrastructure development of translational biomedical research centers is a form of public health intervention. Establishing rigorous methods for measuring center success and outcomes is essential to justify continued funding. Methods. Bibliometric data compiled from a 5-year funding cycle of a neurodegeneration and translational neuroscience research center was analyzed using the package bibliometrix for open source software R and the NIH-developed research tool iCite. Results. The research team and their collaborators (n=485) produced 157 grant-citing publications from 2015-2020. The science was produced by small research teams clustered around three main communities of topics: Alzheimer's Disease, …
Near-Field Imaging Of Plasmonic Nanopatch Antennas With Integrated Semiconductor Quantum Dots, Vasudevan Iyer, Yoong Sheng Phang, Andrew Butler, Jiyang Chen, Brian Lerner, Christos Argyropoulos, Thang Hoang, Benjamin Lawrie
Near-Field Imaging Of Plasmonic Nanopatch Antennas With Integrated Semiconductor Quantum Dots, Vasudevan Iyer, Yoong Sheng Phang, Andrew Butler, Jiyang Chen, Brian Lerner, Christos Argyropoulos, Thang Hoang, Benjamin Lawrie
Department of Electrical and Computer Engineering: Faculty Publications
Plasmonic nanopatch antennas that incorporate dielectric gaps hundreds of picometers to several nanometers thick have drawn increasing attention over the past decade because they confine electromagnetic fields to grossly sub-diffraction-limited volumes. Substantial control over the optical properties of excitons and color centers confined within these plasmonic cavities has already been demonstrated with far-field optical spectroscopies, but near-field optical spectroscopies are essential for an improved understanding of the plasmon–emitter interaction at the nanoscale. Here, we characterize the intensity and phase-resolved plasmonic response of isolated nanopatch antennas by cathodoluminescence microscopy. Furthermore, we explore the distinction between optical and electron beam spectroscopies of …
Design Optimization And Experimental Study Of Coreless Axial-Flux Pm Machines With Wave Winding Pcb Stators, Peng Han, Damien Lawhorn, Yaser Chulaee, Donovin Lewis, Greg Heins, Dan M. Ionel
Design Optimization And Experimental Study Of Coreless Axial-Flux Pm Machines With Wave Winding Pcb Stators, Peng Han, Damien Lawhorn, Yaser Chulaee, Donovin Lewis, Greg Heins, Dan M. Ionel
Power and Energy Institute of Kentucky Faculty Publications
This paper presents a systematic design optimization and experimental study of coreless axial-flux permanent magnet (AFPM) machines with wave winding printed circuit board (PCB) stators. Existing PCB winding configurations are briefly reviewed and compared to serve as a performance reference. A new concept –the “macro coil”– is proposed to model PCB stator windings in 3D finite element analysis (FEA) to facilitate large-scale multi-objective optimization with the winding eddy current losses evaluated in each design candidate. The detailed trace-by-trace model for a selected optimal design is then built to check the voltage difference between parallel paths and the resulting circulating currents. …
Political Processes Of Displacement In Infrastructure Development: The Case Of Aldeia Da Luz And The Alqueva Dam, Cordelia Walz
Political Processes Of Displacement In Infrastructure Development: The Case Of Aldeia Da Luz And The Alqueva Dam, Cordelia Walz
Independent Study Project (ISP) Collection
In 2002, the residents of Aldeia da Luz left their village for the final time, displaced to make room for the Alqueva Dam, a massive regional hydropower and irrigation project almost half a century in the making. The Alqueva Multipurpose Project was marketed by the Portuguese government as a way to develop the impoverished region of the Alentejo and bring innovation to the agricultural sector. The village of Luz was the only physical obstacle to this goal and, therefore, its residents were dispossessed, sacrificed for the development of the greater Alentejo region. However, unlike many other large-scale infrastructure projects that …
Design Optimization Of A Very High Power Density Motor With A Reluctance Rotor And A Modular Stator Having Pms And Toroidal Windings, Peng Han, Murat G. Kesgin, Dan M. Ionel, Rohan Gosalia, Nakul Shah, Charles J. Flynn, Chandra Sekhar Goli, Somasundaram Essakiappan, Madhav Manjrekar
Design Optimization Of A Very High Power Density Motor With A Reluctance Rotor And A Modular Stator Having Pms And Toroidal Windings, Peng Han, Murat G. Kesgin, Dan M. Ionel, Rohan Gosalia, Nakul Shah, Charles J. Flynn, Chandra Sekhar Goli, Somasundaram Essakiappan, Madhav Manjrekar
Power and Energy Institute of Kentucky Faculty Publications
This paper proposes a new high power density permanent magnet (PM) motor design for traction applications to achieve the 50kW/L target set by the US Department of Energy by increasing the torque capability and operating speed compared to conventional PM machine topologies. A large-scale multi-objective design optimization based on 2D finite element analysis (FEA) and differential evolution algorithm was conducted to achieve the best trade-off among high efficiency, high power density and high power factor. The torque-speed envelopes are also checked for the Pareto front designs to make sure they have a constant power speed ratio of at least 3:1. …
Generalized Energy Storage Model-In-The-Loop Suitable For Energy Star And Cta-2045 Control Types, Huangjie Gong, Evan S. Jones, A. H. M. Jakaria, Aminul Huque, Ajit Renjit, Dan M. Ionel
Generalized Energy Storage Model-In-The-Loop Suitable For Energy Star And Cta-2045 Control Types, Huangjie Gong, Evan S. Jones, A. H. M. Jakaria, Aminul Huque, Ajit Renjit, Dan M. Ionel
Power and Energy Institute of Kentucky Faculty Publications
The paper proposes a generalized energy storage (GES) model for battery energy storage systems (BESS), electric water heaters (EWH) and heating, ventilation, and air-conditioning (HVAC) systems. The analogies, including state of charge versus water temperature differential, are identified and explained, and models-in-the-loop (MIL) are introduced, which are compatible with the Energy Star and CTA-2045 general specifications and command types. Emphasis is placed on the proposed EWH model as it needfully fulfills a gap in present literature. The corresponding MIL has been implemented in the DER integration testbed, which was originally developed by EPRI, and satisfactorily validated against experimental results. A …
On The Modeling Of Bearing Voltage And Current In Pwm Converter-Fed Electric Machines Using Electromagnetic Finite Element Analysis, Peng Han, Yibin Zhang, Murat G. Kesgin, Greg Heins, Dean Patterson, Mark Thiele, Dan M. Ionel
On The Modeling Of Bearing Voltage And Current In Pwm Converter-Fed Electric Machines Using Electromagnetic Finite Element Analysis, Peng Han, Yibin Zhang, Murat G. Kesgin, Greg Heins, Dean Patterson, Mark Thiele, Dan M. Ionel
Power and Energy Institute of Kentucky Faculty Publications
Bearing voltages and resulting currents in electric machines driven by PWM converters with fast switching and high dv/dt can cause premature bearing failures. With the transition from conventional Si devices to wide bandgap (WBG) devices and increase in switching frequency, bearing voltages and currents become more significant and need to be addressed from the early design stage. This paper proposes to use coupled field-circuit electromagnetic finite element analysis (FEA) to model bearing voltage and current in electric machines, which takes into account the influence of distributed winding conductors and frequency-dependent winding RL parameters. The three known bearing current types are …
Role Of Estrogen In Regulating Diet-Induced Obesity In Females, Ahmed Aladhami
Role Of Estrogen In Regulating Diet-Induced Obesity In Females, Ahmed Aladhami
Theses and Dissertations
Menopause puts a female at risk for several chronic diseases, including an increased risk of obesity. Estrogens are major sex hormones of females that dramatically decrease during menopause. Several murine studies have established the crucial role of estrogen and estrogen receptor alpha (ERα) on energy homeostasis, glucose metabolism, and insulin action. However, previous works have produced contradicting findings, hence, further work is needed to optimize better outcomes. Therefore, my dissertation focuses on optimizing and characterizing different estrogen-deficient models, as well as using novel double transgenic inducible and tissue-specific models that overexpress aromatase (estrogen producing enzyme) and estrogen receptor isomers alpha …
The Effect Of Low Dose Penicillin On Tumor Development In ApcMin/+ Mice, Kinsey Ann Sierra Meggett
The Effect Of Low Dose Penicillin On Tumor Development In ApcMin/+ Mice, Kinsey Ann Sierra Meggett
Theses and Dissertations
Antibiotics have been our most effective weapon against bacterial infections since their discovery in the early 1900s. Their use has been critical in reducing mortality rate from infectious diseases. However, in the last few decades, the overuse of antibiotics, beginning at an early age and into adulthood, has become a growing concern globally. Penicillin is one of many extensively used antibiotics in early childhood that has been used to treat childhood infections. Recent studies showed that exposure to low dose penicillin can have adverse effects leading to chronic illness such as diabetes, allergies, inflammation, and susceptibility to obesity, with the …
Impact Of Acetylcholine On Internal Pathways To Basal Amygdala Pyramidal Neurons, Tyler Daniel Anderson-Sieg
Impact Of Acetylcholine On Internal Pathways To Basal Amygdala Pyramidal Neurons, Tyler Daniel Anderson-Sieg
Theses and Dissertations
The basolateral nuclear complex of the amygdala (BNC) – consisting of the lateral (LA), basolateral (BL), and basomedial nuclei (BM) – detects salient environmental stimuli (cue-detection) and motivates appropriate behavioral responses to their implied meaning (cue-guided behavior) via a precise pattern of internal circuitry. Glutamatergic signals representing environmental stimuli enter the LA and split into parallel streams that activate pyramidal neurons (PNs) in the anterior and posterior BL (BLa and BLp), which putatively mediate negative and positive emotions, respectively. The BL is the most densely innervated target of the cholinergic basal forebrain (CBF) and ACh transients (phasic ACh) in cortex …
Operating Strategies And Disturbance Characterization For Dc Microgrids, Miles Leonard-Albert
Operating Strategies And Disturbance Characterization For Dc Microgrids, Miles Leonard-Albert
Theses and Dissertations
The present state of the electrical grid is unable to meet the demands of transmission. Digital twin technology provides a promising solution to this problem by allowing for analysis and control of distributed energy resources. This thesis presents initial work towards development of a digital twin for a DC power system. Two versions of the DC power system are created and evaluated against randomly generated load profiles. System performance is evaluated on the basis of the quantity of the load that is unserviced by the generation and energy storage. Energy storage operating strategies that modify the model to prioritize different …
Impaired Metabolic Flexibility In A Mouse Model Of Leigh Syndrome, Richard Sterling Mccain Jr
Impaired Metabolic Flexibility In A Mouse Model Of Leigh Syndrome, Richard Sterling Mccain Jr
Theses and Dissertations
Metabolic dysfunction burdens tissues with high energy demands, particularly the brain. Leigh syndrome is a mitochondrial encephalopathy stemming from genetic defects in the electron transport chain. Leigh syndrome patients develop lactic acidosis, ataxia, bilateral necrotizing lesions in the brainstem and basal ganglia, lesion microgliosis, and eventually death due to respiratory failure. The NADH dehydrogenase [ubiquinone] iron-sulfur protein 4 (NDUFS4) knockout mouse is an established model of Leigh syndrome due to impaired assembly of mitochondrial Complex I that develops motoric deficits and necrotizing lesions in the brainstem vestibular nuclei and olfactory bulb. In addition to the Complex I-derived bioenergetics defect, altered …
Deep Learning Approach For Screening Autism Spectrum Disorder In Children With Facial Images And Analysis Of Ethnoracial Factors In Model Development And Application, Angelina Lu, Marek Perkowski
Deep Learning Approach For Screening Autism Spectrum Disorder In Children With Facial Images And Analysis Of Ethnoracial Factors In Model Development And Application, Angelina Lu, Marek Perkowski
Electrical and Computer Engineering Faculty Publications and Presentations
Autism spectrum disorder (ASD) is a developmental disability that can cause significant social, communication, and behavioral challenges. Early intervention for children with ASD can help to improve their intellectual ability and reduces autistic symptoms. Multiple clinical researches have suggested that facial phenotypic differences exist between ASD children and typically developing (TD) children. In this research, we propose a practical ASD screening solution using facial images through applying VGG16 transfer learning-based deep learning to a unique ASD dataset of clinically diagnosed children that we collected. Our model produced a 95% classification accuracy and 0.95 F1-score. The only other reported study using …
Increased Detectivity And Low Temperature Performance Analysis Of Sub-20Μm Micropixel Array A1gan Uv Photodiodes, Samia Islam
Increased Detectivity And Low Temperature Performance Analysis Of Sub-20Μm Micropixel Array A1gan Uv Photodiodes, Samia Islam
Theses and Dissertations
This thesis is divided into two sections. At first, we demonstrate ~1.5x detectivity increase in AlGaN photodiodes on sapphire using distributed micropixel arrays with 5-15 µm pixel diameter. This is due to the ~10x larger chip footprint of the 5um diameter micropixel arrays compared to planar control structures with identical p contact area. The responsivity of the larger areas was the same as that of the control structure despite the larger footprint while the dark currents, an indicator of noise, remained unchanged. The photocurrent generated between pixels was collected due to transmission line effects connecting the pixels separated by 5um, …
Ultrawide Bandgap Algan-Channel Metal Oxide Semiconductor Heterostructure Field Effect Transistors With High-K Gate Dielectrics, Md Abu Shahab Mollah
Ultrawide Bandgap Algan-Channel Metal Oxide Semiconductor Heterostructure Field Effect Transistors With High-K Gate Dielectrics, Md Abu Shahab Mollah
Theses and Dissertations
Ultra-wide Band Gap (UWBG) (EG > 3.4 eV) AlxGa1-xN channel devices are promising candidates for compact next-generation power electronics due to the scaling of the breakdown field with alloy composition. The huge opportunity in consumer electronics is the major driving force behind the recent developments of UWBG AlGaN-channel HEMTs. One of the most critical issues limiting the device performance at high power level is device degradation primarily caused by gate leakage current. Use of SiO2 gate insulator is a standard method to suppress gate leakage but it causes threshold voltage shift towards more negative requiring …
A Novel Model To Study Adipose-Derived Stem Cell Differentiation, Austin N. Worden
A Novel Model To Study Adipose-Derived Stem Cell Differentiation, Austin N. Worden
Theses and Dissertations
The use of three-dimensional (3D) culture systems (hydrogels) and adipose-derived stem cells (ADSCs) in regenerative medicine to advance early-stage investigation and modeling of the mechanisms of diseases, treatments, targets, etc. has recently increased. ADSCs, specifically, are utilized due to their innate programming during embryogenesis and in adult tissues in addition to their ability to differentiate into mesodermal, endodermal, and ectodermal cell-specific lineages. Of importance is that these advancements do not involve a model specimen (i.e. mice or rats) and simulate the numerous conflicting signals a migrating cell is exposed to in vivo such as chemokines, extracellular matrix (ECM), growth factors, …
A 12-Bit 1gs/S Sar-Assisted Pipeline Adc With Harmonic Injecting Residue Amplifier, Liang Fang
A 12-Bit 1gs/S Sar-Assisted Pipeline Adc With Harmonic Injecting Residue Amplifier, Liang Fang
Electrical Engineering Theses and Dissertations
Advanced wireless applications require a medium resolution Radio Frequency (RF) sampling Analog to Digital Converter (ADC). By performing sampling of ADC at RF frequency, the mixer and Intermediate Frequency (IF) amplifier can be implemented in the digital domain, which helps the receiver eliminate troublesome mixing spurs and potentially improves the software-defined ratio of the entire system. By combing the merits of the energy-efficient Successive Approximation Register (SAR) ADC and the high-speed pipeline ADC, the SAR-assisted pipeline ADC achieves superior performance in high-speed medium-resolution ADC. However, with the advance of the process, due to the pure analog implementation, the residue amplifier …
A Unified Framework Of Deep Learning-Based Facial Expression Recognition System For Diversified Applications, Sanoar Hossain, Saiyed Umer, Vijayan K. Asari, Ranjeet Kumar Rout
A Unified Framework Of Deep Learning-Based Facial Expression Recognition System For Diversified Applications, Sanoar Hossain, Saiyed Umer, Vijayan K. Asari, Ranjeet Kumar Rout
Electrical and Computer Engineering Faculty Publications
This work proposes a facial expression recognition system for a diversified field of appli- cations. The purpose of the proposed system is to predict the type of expressions in a human face region. The implementation of the proposed method is fragmented into three components. In the first component, from the given input image, a tree-structured part model has been applied that predicts some landmark points on the input image to detect facial regions. The detected face region was normalized to its fixed size and then down-sampled to its varying sizes such that the advantages, due to the effect of multi-resolution …
Expanding Temperature Sensing For The Orion Bms 2, Samuel J. Parker
Expanding Temperature Sensing For The Orion Bms 2, Samuel J. Parker
University Honors Theses
Formula SAE (FSAE) is an annual collegiate design competition that takes place across the globe. Portland State University’s team, Viking Motorsports, was committed to designing an Electric Vehicle (EV) for the 2021 FSAE competition. The team designed a completely custom lithium-ion cell battery that is managed by an Orion BMS 2 battery management system. The FSAE rulebook requires a robust temperature monitoring system for any EV power supply. The Orion BMS 2 can only directly collect data from eight temperature sensors, which is not enough to meet FSAE regulation. However, the BMS can be configured to monitor many more sensors …
Simple, Cost-Effective Fabrication, And Flow Dynamics Analysis Of A Passive Microfluidic Mixer Using 3d Printing And Soft Lithography, Md Fazlay Rubby, Mohammad Salman Parvez, Nazmul Islam
Simple, Cost-Effective Fabrication, And Flow Dynamics Analysis Of A Passive Microfluidic Mixer Using 3d Printing And Soft Lithography, Md Fazlay Rubby, Mohammad Salman Parvez, Nazmul Islam
Electrical and Computer Engineering Faculty Publications
Simple and low-cost fabrication of microfluidic devices has attracted considerable attention among researchers. The traditional soft lithography fabrication method requires expensive equipment like a UV exposure system and mask fabrication facility. In this work, an alternative and low-cost UV exposure system was introduced along with an alternative mask fabrication system. A previously reported passive microfluidic mixer was fabricated successfully using this modified soft lithography method. Challenges were presented during this modified fabrication method. Another emerging potential alternative for the fabrication of microfluidic mixers is 3D printing. It was also used in this experiment to fabricate a passive micromixer. This method …
Machine Learning For High-Fidelity Prediction Of Cement Hydration Kinetics In Blended Systems, Rachel Cook, Taihao Han, Alaina Childers, Cambria Ryckman, Kamal Khayat, Hongyan Ma, Jie Huang, Aditya Kumar
Machine Learning For High-Fidelity Prediction Of Cement Hydration Kinetics In Blended Systems, Rachel Cook, Taihao Han, Alaina Childers, Cambria Ryckman, Kamal Khayat, Hongyan Ma, Jie Huang, Aditya Kumar
Civil, Architectural and Environmental Engineering Faculty Research & Creative Works
The production of ordinary Portland cement (OPC), the most broadly utilized man-made material, has been scrutinized due to its contributions to global anthropogenic CO2 emissions. Thus -- to mitigate CO2 emissions -- mineral additives have been promulgated as partial replacements for OPC. However, additives -- depending on their physiochemical characteristics -- can exert varying effects on OPC's hydration kinetics. Therefore -- in regards to more complex systems -- it is infeasible for semi-empirical kinetic models to reveal the underlying nonlinear composition-property (i.e., reactivity) relationships. In the past decade or so, machine learning (ML) has arisen as a promising, …
Effect Of Non-Planar Tungsten V-Electrode Pattern In A 3d Printed Microfluidic System, Mohammad Salman Parvez, Md Fazlay Rubby, Shanzida Kabir, Meah Imtiaz Zulkarnain, Nazmul Islam
Effect Of Non-Planar Tungsten V-Electrode Pattern In A 3d Printed Microfluidic System, Mohammad Salman Parvez, Md Fazlay Rubby, Shanzida Kabir, Meah Imtiaz Zulkarnain, Nazmul Islam
Electrical and Computer Engineering Faculty Publications
Manipulation, guiding, and focusing of particles is an important phenomenon in the area of biomedical research. In most cases, particles are suspended in a microfluidic environment. These microfluidic environments can be high or low conductive. Most importantly these flows seeded with the micro-particles are manipulated and guided in microfluidic channels. Microfluidic channels have very low dimensions and considering the flow rate the characteristic of the flow in a microfluidic channel is laminar in nature. There are many micromachining methods available for fabricating microfluidic channels such as soft-lithography, wet etching, electroforming, PDMS molding, laser ablation followed by wet etching but in …
Study Of The Effect Of B-Cell-Intrinsic Mhcii Antigen Presentation On Germinal Center B Cell Evolution Using The Brainbow Mouse Model, Nia Hall
Theses and Dissertations
Major histocompatibility complex class II (MHCII) are molecules that are essential for B cell activation, as well as clonal competition among activated B cell clones during germinal center (GC) reactions. However, it is unknown to what extent MHCII drives the selection of some clones over others. This is of particular importance since MHCII is highly polymorphic with the ability to indirectly alter gutmicrobiome composition by altering the immunoglobulin A (IgA) repertoire. To study this, we utilized a novel triple-transgenic mouse model to assess how B-cellintrinsic MHCII influences GC responses and GC clonal diversity, with an eyeforward to understanding the relevance …
The Role Pde11a4 Signaling And Compartmentalization In Social Behavior, Kaitlyn Pilarzyk
The Role Pde11a4 Signaling And Compartmentalization In Social Behavior, Kaitlyn Pilarzyk
Theses and Dissertations
People tend to be social by nature. Being socially connected not only helps people live longer and healthier lives, but being an engaged and contributing member of society strengthens our communities overall. Maintaining intact social behaviors is key to maintaining this wellbeing, with disruptions negatively affecting both mental and physical health. Indeed, social isolation and feelings of loneliness can significantly increase a person’s risk of premature death, heart disease, and stroke as well as depression, anxiety, suicide, and dementia. Maintaining the ability to create and store social memory with age is, therefore, key to maintaining proper social behaviors. Unfortunately, individuals …
Real Time Simulation And Hardware In The Loop Methods For Power Electronics Power Distribution Systems, Michele Difronzo
Real Time Simulation And Hardware In The Loop Methods For Power Electronics Power Distribution Systems, Michele Difronzo
Theses and Dissertations
System level testing of Power Electronics Power Distribution Systems (PEPDS) can be challenging when fine temporal resolution is required (time step below 100-200ns). In the recent years, our research group has proposed various methods to simulate in real-time PEPDS using FPGAs and time step as small as 50ns. While the proposed methods allow achieving the desired temporal resolution, they are extremely demanding in terms of resources usage and the size of the PEPDS that can be simulated on a single FPGA is strongly limited.
In this dissertation -work that takes as an example application the US Navy electric Ship Zonal …