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Biomedical Engineering and Bioengineering Commons

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Stability Analysis Of A More General Class Of Systems With Delay-Dependent Coefficients, Chi Jin, Keqin Gu, Islam Boussaada, Silviu-Iulian Niculescu 2019 Laboratoire des Signaux et Syst`emes (L2S) CentraleSup´elec-CNRS-Universit´e Paris Sud, 3 rue Joliot- Curie 91192 Gif-sur-Yvette cedex, France.

Stability Analysis Of A More General Class Of Systems With Delay-Dependent Coefficients, Chi Jin, Keqin Gu, Islam Boussaada, Silviu-Iulian Niculescu

SIUE Faculty Research, Scholarship, and Creative Activity

This paper presents a systematic method to analyse the stability of systems with single delay in which the coefficient polynomials of the characteristic equation depend on the delay. Such systems often arise in, for example, life science and engineering systems. A method to analyze such systems was presented by Beretta and Kuang in a 2002 paper, but with some very restrictive assumptions. This work extends their results to the general case with the exception of some degenerate cases. It is found that a much richer behavior is possible when the restrictive assumptions are removed. The interval of interest for the ...


Biomass And Phycocyanin From Oil And Natural Gas Extraction Produced Water Utilizing A Cyanobacteria Dominated Rotating Algal Biofilm Reactor (Rabr), Jonathan L. Wood 2018 Utah State University

Biomass And Phycocyanin From Oil And Natural Gas Extraction Produced Water Utilizing A Cyanobacteria Dominated Rotating Algal Biofilm Reactor (Rabr), Jonathan L. Wood

All Graduate Theses and Dissertations

The production of cyanobacterial biofilm biomass and phycocyanin from Rotating Algal Biofilm Reactors utilizing undiluted produced water from oil and natural gas extraction as a culture medium was investigated in this study. Produced water is the largest waste stream generated by the oil and natural gas industries and represents a large volume of non-potable water that may be available for algae culture with minimal impact on freshwater resources. Combining the use of produced wastewater as culture medium with the production of high value algal pigments, such as phycocyanin, may increase the economic viability of algae culture and wastewater purification. High ...


Regulation Of Cellular Patterning Through The Extracellular Matrix, Lewis Scott, Lauren Griggs, Vani Narayanan, Daniel Conway PhD, Seth H. Weinberg PhD, Christopher Lemmon PhD 2018 Virginia Commonwealth University

Regulation Of Cellular Patterning Through The Extracellular Matrix, Lewis Scott, Lauren Griggs, Vani Narayanan, Daniel Conway Phd, Seth H. Weinberg Phd, Christopher Lemmon Phd

Biology and Medicine Through Mathematics Conference

No abstract provided.


Intercellular Sodium Nanodomain Signaling Regulates Repolarization In Cardiac Tissue, Madison Nowak, Seth Weinberg Ph.D. 2018 Virginia Commonwealth University

Intercellular Sodium Nanodomain Signaling Regulates Repolarization In Cardiac Tissue, Madison Nowak, Seth Weinberg Ph.D.

Biology and Medicine Through Mathematics Conference

No abstract provided.


Investigating Smoke Exposure And Chronic Obstructive Pulmonary Disease (Copd) With A Calibrated Agent Based Model (Abm) Of In Vitro Fibroblast Wound Healing., J Alex Ratti, Angela Reynolds, Rebecca L. Heise 2018 Virginia Commonwealth University

Investigating Smoke Exposure And Chronic Obstructive Pulmonary Disease (Copd) With A Calibrated Agent Based Model (Abm) Of In Vitro Fibroblast Wound Healing., J Alex Ratti, Angela Reynolds, Rebecca L. Heise

Biology and Medicine Through Mathematics Conference

No abstract provided.


Chemotherapeutic Drug Cytotoxicity Measurement With A 3d Biomimetic Microfluidic Device And Computational Fluid Dynamics Model, Maryam Moarefian, Caroline Jones, Luke Achenie, Danesh Tafti 2018 Virginia Polytechnic Institute and State University

Chemotherapeutic Drug Cytotoxicity Measurement With A 3d Biomimetic Microfluidic Device And Computational Fluid Dynamics Model, Maryam Moarefian, Caroline Jones, Luke Achenie, Danesh Tafti

Biology and Medicine Through Mathematics Conference

No abstract provided.


Quantifying Effects Of Neutrophil Memory On Migration Patterns Using Microfluidic Platforms And Ode Modeling Of The Mechanistic Molecular Pathways, Brittany P. Boribong, Mark J. Lenzi, Mirjam Sarah Kadelka, Stanca Ciupe, Liwu Li, Caroline N. Jonea 2018 Virginia Polytechnic Institute and State University

Quantifying Effects Of Neutrophil Memory On Migration Patterns Using Microfluidic Platforms And Ode Modeling Of The Mechanistic Molecular Pathways, Brittany P. Boribong, Mark J. Lenzi, Mirjam Sarah Kadelka, Stanca Ciupe, Liwu Li, Caroline N. Jonea

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong 2018 Oklahoma State University - Main Campus

Modeling Pharmaceutical Inhibition Of Glucose-Stimulated Renin-Angiotensin System In Kidneys, Ashlee N. Ford Versypt, Minu R. Pilvankar, Hui Ling Yong

Biology and Medicine Through Mathematics Conference

No abstract provided.


Kinematic Analysis Of Spinal Cord Injury Animals Treated With A Neurotrophin-Infused Scaffold And Body Weight Supported Treadmill Training, Alexander Herman 2018 Rowan University

Kinematic Analysis Of Spinal Cord Injury Animals Treated With A Neurotrophin-Infused Scaffold And Body Weight Supported Treadmill Training, Alexander Herman

Theses and Dissertations

Spinal Cord Injury (SCI) is a condition that affects around 250,000 Americans with no cure. Existing treatments rely on physical therapies such as body weight support treadmill training (BWSTT). Treatments currently being researched include the use of implantable cells and biomaterials. Our study investigated the changes in locomotive gait and range of motion via a combinational treatment using a bioengineered scaffold [poly (N-isopropyl acrylamide) polyethylene glycol (PNIPAAm-g-PEG) with BDNF and NT-3] and rehabilitation training using BWSTT in a clinically relevant contusion SCI animal model. Five different groups of animals (Sham, Injury, BWSTT, Implant, and Combinational) were tested on a ...


Radical Social Ecology As Deep Pragmatism: A Call To The Abolition Of Systemic Dissonance And The Minimization Of Entropic Chaos, Arielle Brender 2018 Fordham University

Radical Social Ecology As Deep Pragmatism: A Call To The Abolition Of Systemic Dissonance And The Minimization Of Entropic Chaos, Arielle Brender

Student Theses 2015-Present

This paper aims to shed light on the dissonance caused by the superimposition of Dominant Human Systems on Natural Systems. I highlight the synthetic nature of Dominant Human Systems as egoic and linguistic phenomenon manufactured by a mere portion of the human population, which renders them inherently oppressive unto peoples and landscapes whose wisdom were barred from the design process. In pursuing a radical pragmatic approach to mending the simultaneous oppression and destruction of the human being and the earth, I highlight the necessity of minimizing entropic chaos caused by excess energy expenditure, an essential feature of systems that aim ...


The Road Towards Image-Computable Models Of Human Visual Grasp Planning, Guido Maiello, Lina K. Klein, Vivian C. Paulun, Katherine R. Storrs, Roland W. Fleming 2018 University of Gießen

The Road Towards Image-Computable Models Of Human Visual Grasp Planning, Guido Maiello, Lina K. Klein, Vivian C. Paulun, Katherine R. Storrs, Roland W. Fleming

MODVIS Workshop

No abstract provided.


A Feature-Based Model Of Visually Perceiving Deformable Objects, Vivian C. Paulun, Filipp Schmidt, Roland W. Fleming 2018 Justus Liebig University, Giessen

A Feature-Based Model Of Visually Perceiving Deformable Objects, Vivian C. Paulun, Filipp Schmidt, Roland W. Fleming

MODVIS Workshop

No abstract provided.


Chronic Nerve Interfacing Utilizing Graft-Embedded Regenerative Macro-Sieve Electrodes, Amrita Nishtala 2018 Boston University

Chronic Nerve Interfacing Utilizing Graft-Embedded Regenerative Macro-Sieve Electrodes, Amrita Nishtala

Engineering and Applied Science Theses & Dissertations

Custom-designed macro-sieve electrodes represent a novel means of facilitating chronic high specificity nerve stimulation needed to control distal nerve musculature and restore sensorimotor function. Implantation of these electrodes requires the transection of the nerve, which has shown to disrupt muscle fiber distribution. This present study assesses the feasibility of implementing these electrodes in an end-to-side nerve graft. The macro-sieve electrodes were fabricated and micro-surgically implanted into 3.2 cm nerve autografts harvested from the sciatic nerve of 12 male Lewis rats. Electrode-enabled nerve grafts were micro-surgically implanted in an end-to-side manner into donor rat sciatic nerves without the need for ...


Analyzing Memcapacitive Capabilities Of Lipid And Polymer Bilayers For Use In Smart Materials, Megan Pitz 2018 University of Tennessee, Knoxville

Analyzing Memcapacitive Capabilities Of Lipid And Polymer Bilayers For Use In Smart Materials, Megan Pitz

EURēCA: Exhibition of Undergraduate Research and Creative Achievement

Neuromorphic engineering involves designing artificial neural systems that mimic the way neuron circuits in the brain process information and make computations. It took the fourth most powerful computer in the world (with 705,024 processor cores and 1.4 million GB of RAM) 40 minutes to simulate just one second of human brain activity. This shows a clear difference of energy use in the human brain versus modern computers; neuromorphic engineering could be how we mimic the computing power of the brain to create energy-efficient, neuron-based computers. Memristors and memcapacitors are proposed circuit elements with memory components. Memristors have been ...


An Active Efficient Coding Model Of The Development Of Amblyopia, Samuel Eckmann, Lukas Klimmasch, Bertram Shi, Jochen Triesch 2018 Frankfurt Institute for Advanced Studies

An Active Efficient Coding Model Of The Development Of Amblyopia, Samuel Eckmann, Lukas Klimmasch, Bertram Shi, Jochen Triesch

MODVIS Workshop

No abstract provided.


Design Of A Distributed Real-Time E-Health Cyber Ecosystem With Collective Actions: Diagnosis, Dynamic Queueing, And Decision Making, Yanlin Zhou 2018 University of Nebraska - Lincoln

Design Of A Distributed Real-Time E-Health Cyber Ecosystem With Collective Actions: Diagnosis, Dynamic Queueing, And Decision Making, Yanlin Zhou

Theses, Dissertations, and Student Research from Electrical & Computer Engineering

In this thesis, we develop a framework for E-health Cyber Ecosystems, and look into different involved actors. The three interested parties in the ecosystem including patients, doctors, and healthcare providers are discussed in 3 different phases. In Phase 1, machine-learning based modeling and simulation analysis is performed to remotely predict a patient's risk level of having heart diseases in real time. In Phase 2, an online dynamic queueing model is devised to pair doctors with patients having high risk levels (diagnosed in Phase 1) to confirm the risk, and provide help. In Phase 3, a decision making paradigm is ...


Developing Photoacoustic Tomography Devices For Translational Medicine And Basic Science Research, Tsz Wai Wong 2018 Washington University in St. Louis

Developing Photoacoustic Tomography Devices For Translational Medicine And Basic Science Research, Tsz Wai Wong

Engineering and Applied Science Theses & Dissertations

Photoacoustic (PA) tomography (PAT) provides volumetric images of biological tissue with scalable spatial resolutions and imaging depths, while preserving the same imaging contrast—optical absorption. Taking the advantage of its 100% sensitivity to optical absorption, PAT has been widely applied in structural, functional, and molecular imaging, with both endogenous and exogenous contrasts, at superior depths than pure optical methods. Intuitively, hemoglobin has been the most commonly studied biomolecule in PAT due to its strong absorption in the visible wavelength regime.

One of the main focuses of this dissertation is to investigate an underexplored wavelength regime—ultraviolet (UV), which allows us ...


Functional Electrical Stimulation Of Peripheral Nerve Tissue Via Regenerative Sieve Microelectrodes, Matthew Reagan Macewan 2018 Washington University in St. Louis

Functional Electrical Stimulation Of Peripheral Nerve Tissue Via Regenerative Sieve Microelectrodes, Matthew Reagan Macewan

Engineering and Applied Science Theses & Dissertations

Functional electrical stimulation (FES) of peripheral nervous tissue offers a promising method for restoring motor function in patients suffering from complex neurological injuries. However, existing microelectrodes designed to stimulate peripheral nerve are unable to provide the type of stable, selective interface required to achieve near-physiologic control of peripheral motor axons and distal musculature. Regenerative sieve electrodes offer a unique alternative to such devices, achieving a highly stable, selective electrical interface with independent groups of regenerated nerve fibers integrated into the electrode. Yet, the capability of sieve electrodes to functionally recruit regenerated motor axons for the purpose of muscle activation remains ...


Silane Modulation Of Protein Conformation And Self-Assembly, Abul Bashar Mohammad Giasuddin 2018 Utah State University

Silane Modulation Of Protein Conformation And Self-Assembly, Abul Bashar Mohammad Giasuddin

All Graduate Theses and Dissertations

This research focused on development of nanoparticle- based therapeutics against amyloid fibrils. Amyloid fibrils are associated with various diseases such as Parkinson’s, Huntington’s, mad cow disease, Alzheimer’s, and cataracts. Amyloid fibrils develop when proteins change their shape from a native form to a pathogenic “misfolded” form. The misfolded proteins have the ability to recruit more native proteins into the pathogenic forms, which self-assemble into amyloid fibrils that are hallmarks of the various protein-misfolding diseases listed above. Amyloid fibrils are highly resistant to degradation, which may contribute to the symptoms of amyloid diseases. Synthetic drugs, natural compounds, and ...


The Use Of Microfluidics And Dielectrophoresis For Separation, Concentration, And Identification Of Bacteria, Cynthia Hanson 2018 Utah State University

The Use Of Microfluidics And Dielectrophoresis For Separation, Concentration, And Identification Of Bacteria, Cynthia Hanson

All Graduate Theses and Dissertations

Typical bacterial analysis involves culturing and visualizing colonies on an array of agar plates. The growth patterns and colors among the array are used to identify the bacteria. For fast growing bacteria such as Escherichia coli, analysis will take one to two days. However, slow growing bacteria such as mycobacteria can take weeks to identify. In addition, there are some species of bacteria that are viable but nonculturable. This lengthy analysis time is unacceptable for life-threatening infections and emergency situations. It is clear that to decrease the analysis of the bacteria, the culturing and growth steps must be avoided. The ...


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