Bioelectrical and Neuroengineering Commons^™

Reading And Wirelessly Sending Eeg Signals Using Arduinos And Xbee Radios To Control A Robot, Andrew Paul Simms

Electrical Engineering Undergraduate Honors Theses

The objective of this project is to develop an EEG device that can read brainwaves from an individual, analyze the data, and use the result to send a wireless signal using Arduinos and XBee Radios to a Boe-bot to perform an action. One of the goals of this project is to read EEG data with a higher sampling frequency than a previously manufactured EEG device. The second part of the project used the device developed to differentiate an individual’s thinking between right and left and then send a simple signal to a robot using an XBee radio to perform ...

Neuromodulation: Action Potential Modeling, Vladimir Ruzov

Master's Theses and Project Reports

There have been many different studies performed in order to examine various properties of neurons. One of the most important properties of neurons is an ability to originate and propagate action potential. The action potential is a source of communication between different neural structures located in different anatomical regions. Many different studies use modeling to describe the action potential and its properties. These models mathematically describe physical properties of neurons and analyze and explain biological and electrochemical processes such as action potential initiation and propagation. Therefore, one of the most important functions of neurons is an ability to provide communication ...

Analysis Of Breath-Holding Index As An Assessment Of Cerebrovascular Reactivity, Allison P. Porter, Madison Burger, Mohammed Alwatban, Benjamin Hage, Greg Bashford

UCARE Research Products

Cerebrovascular reactivity (CVR) is a key factor in regulating blood flow into the brain, and a marker for vascular disease. If the brain's regulatory system is not working, a patient may be in serious trouble. Testing of CVR is one method of assessing the brain's regulatory capabilities. Transcranial Doppler ultrasound (TCD) is one tool to measure CVR. In this method, carbon dioxide in the blood is transiently increased (such as with the holding of breath), and the resulting blood flow in the brain is measured. In this study, we are going to measure the variability of the breathholding ...

Multimodal Sensory Integration For Perception And Action In High Functioning Children With Autism Spectrum Disorder, Nicole Marie Gregor Salowitz

Dissertations (2009 -)

Movement disorders are the earliest observed features of autism spectrum disorder (ASD) present in infancy. Yet we do not understand the neural basis for impaired goal-directed movements in this population. To reach for an object, it is necessary to perceive the state of the arm and the object using multiple sensory modalities (e.g. vision, proprioception), to integrate those sensations into a motor plan, to execute the plan, and to update the plan based on the sensory consequences of action. In this dissertation, I present three studies in which I recorded hand paths of children with ASD and typically developing ...

Comparison Of Regular Ringer’S Solution And Glucose Ringer’S Solution On The Longevity Of The Hirudo Medicinalis’ Retzius Cell, Nicole Arielle Peretti

Master's Theses and Project Reports

In 1882, Sydney Ringer, a professor of medicine at University College in London, experimented with the frog ventricle to better understand how each constituent of blood influences contraction. The ultimate goal was to create an artificial circulating fluid to use for the perfusion of isolated organs, in this case, a frog heart. Today, Ringer’s solution is still used in research for physiological studies requiring the survival and maintenance of specimens outside of their host bodies. One such example is the use of medicinal leech ganglia for electrophysiological measurements. In this thesis, I am comparing two Ringer’s solutions, original ...

Investigation Of A Simulated Annealing Cooling Schedule Used To Optimize The Estimation Of The Fiber Diameter Distribution In A Peripheral Nerve Trunk, Arya Vigeh

Master's Theses and Project Reports

In previous studies it was determined that the fiber diameter distribution in a peripheral nerve could be estimated by a simulation technique known as group delay. These results could be further improved using a combinatorial optimization algorithm called simulated annealing. This paper explores the structure and behavior of simulated annealing for the application of optimizing the group delay estimated fiber diameter distribution. Specifically, a set of parameters known as the cooling schedule is investigated to determine its effectiveness in the optimization process.

Simulated annealing is a technique for finding the global minimum (or maximum) of a cost function which may ...

Multimodal Wearable Sensors For Human-Machine Interfaces, Mark Nolan

Doctoral

Certain areas of the body, such as the hands, eyes and organs of speech production, provide high-bandwidth information channels from the conscious mind to the outside world. The objective of this research was to develop an innovative wearable sensor device that records signals from these areas more conveniently than has previously been possible, so that they can be harnessed for communication. A novel bioelectrical and biomechanical sensing device, the wearable endogenous biosignal sensor (WEBS), was developed and tested in various communication and clinical measurement applications.

One ground-breaking feature of the WEBS system is that it digitises biopotentials almost at the ...

Eeg And Emg Sensorimotor Measurements To Assess Proprioception Following Acl Reconstruction, Teagan Frances Northrup

Honors Theses and Capstones

The Anterior Cruciate Ligament (ACL) is the primary source of rotational stability in the knee by preventing the tibia from sliding in front of the femur. When the ACL is torn, it typically must be repaired through reconstructive surgery which results in proprioceptive deficiencies in the knee. Proprioception plays an important role in understanding where one’s knee is in space, sensing movement and reacting accordingly. This study examines an alternative method of measuring proprioceptive responses to a stimulus (motion) by using electromyogram (EMG) and electroencephalogram (EEG) signals to observe muscle and brain activity. Two participants (one with an ACL ...

Bionano Electronics: Magneto-Electric Nanoparticles For Drug Delivery, Brain Stimulation And Imaging Applications, Rakesh Guduru

FIU Electronic Theses and Dissertations

Nanoparticles are often considered as efficient drug delivery vehicles for precisely dispensing the therapeutic payloads specifically to the diseased sites in the patient’s body, thereby minimizing the toxic side effects of the payloads on the healthy tissue. However, the fundamental physics that underlies the nanoparticles’ intrinsic interaction with the surrounding cells is inadequately elucidated. The ability of the nanoparticles to precisely control the release of its payloads externally (on-demand) without depending on the physiological conditions of the target sites has the potential to enable patient- and disease-specific nanomedicine, also known as Personalized NanoMedicine (PNM). In this dissertation, magneto-electric nanoparticles ...

Nano-Pulse Stimulation Ablates Orthotopic Rat Hepatocellular Carcinoma And Induces Innate And Adaptive Memory Immune Mechanisms That Prevent Recurrence, Brittany P. Lassiter, Siqi Guo, Stephen J. Beebe

Bioelectrics Publications

Nano-pulse stimulation (NPS), previously called nsPEFs, induced a vaccine-like effect after ablation of orthotopic N1-S1 hepatocellular carcinoma (HCC), protecting rats from subsequent challenges with N1-S1 cells. To determine immunity, immune cell phenotypes were analyzed in naïve, treated and protected rats. NPS provides a positive, post-ablation immuno-therapeutic outcome by alleviating immunosuppressive T regulatory cells (Treg) in the tumor microenvironment (TME), allowing dendritic cell influx and inducing dynamic changes in natural killer cells (NKs), NKT-cells and T-lymphocytes in blood, spleen and liver. NPS induced specific increases in NKs and NKT-cells expressing CD8 and activation receptors CD314-NKG2D and CD161 (NK1.1) in the ...