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Biomedical Devices and Instrumentation Commons

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Diffusion Modeling And Device Development For Peritoneal Membrane Oxygenation, Liana Hatoum 2016 University of Nebraska - Lincoln

Diffusion Modeling And Device Development For Peritoneal Membrane Oxygenation, Liana Hatoum

Mechanical (and Materials) Engineering -- Dissertations, Theses, and Student Research

Acute respiratory distress syndrome (ARDS) is a pulmonary disease that causes hypoxemia and respiratory failure. The mortality rate for ARDS ranges between 27% and 45%. Current treatments including mechanical ventilation and extracorporeal membrane oxygenation (ECMO) are often associated with high risk complications including barotrauma, infection, thrombosis, and hemorrhage. Alternative pulmonary support techniques are needed to improve the survival rate of patients suffering from ARDS. Previous studies introducing pure O2 gas, perfluorocarbons and red blood cells into the intraperitoneal (IP) cavity have reported no effect or only a mild increase in oxygenation. Here we report peritoneal membrane oxygenation (PMO) using ...


Wheelchair Fatigue Reducer, Aaron Miller, Dennis Andre Norfleet 2016 University of Tennessee, Knoxville

Wheelchair Fatigue Reducer, Aaron Miller, Dennis Andre Norfleet

University of Tennessee Honors Thesis Projects

No abstract provided.


Lost And Found: Use Of Gps Technology To Improve Storage Of Patient Belongings In Hospital Setting, Shelby A. Sievers, Griffin M. Heise, Min G. Kang, Michael Totty 2016 University of Tennessee, Knoxville

Lost And Found: Use Of Gps Technology To Improve Storage Of Patient Belongings In Hospital Setting, Shelby A. Sievers, Griffin M. Heise, Min G. Kang, Michael Totty

University of Tennessee Honors Thesis Projects

No abstract provided.


Design Of Medical Devices For Diagnostics In The Gastrointestinal System, Charles R. Welch 2016 University of Nebraska-Lincoln

Design Of Medical Devices For Diagnostics In The Gastrointestinal System, Charles R. Welch

Mechanical (and Materials) Engineering -- Dissertations, Theses, and Student Research

This thesis presents the design, controls, and testing of two systems: a novel colonoscope locomotion design for diagnostics, and a biosensor capsule that implants a sensor in the small intestine. Each system requires special design considerations for use in the gastrointestinal system.

Colonoscopy procedures are recommended as a screening for colon cancer and related conditions after the age of 50. The need for an improved colonoscope that reduces the colonoscopy time and patient discomfort is apparent. The semi-autonomous device presented here could likely reduce the colonoscopy procedure time by allowing the physician to focus more on the diagnosis and less ...


A Novel Minimally Invasive Tumour Localization Device, Doran Avivi 2016 The University of Western Ontario

A Novel Minimally Invasive Tumour Localization Device, Doran Avivi

Electronic Thesis and Dissertation Repository

Lung cancer is one of the leading causes of death, by cancer. The usual treatment is surgical resection of tumours. However, patients who are weak or have poor pulmonary function are deemed unfit for surgery. For these patients, a minimally-invasive approach is desired. A major problem associated with minimally-invasive approaches is tumour localization in real time and accurate measurement of tool--tissue forces.

This thesis describes the design, analysis, manufacturing and validation of a minimally-invasive instrument for tumour localization, named Palpatron. The instrument has an end effector that is able to support two previously designed jaws, one containing an ultrasound sensor ...


Under The Needle: Ergonomic Issues With Lethal Injection Protocols, Gabriella Hancock 2016 University of Central Florida

Under The Needle: Ergonomic Issues With Lethal Injection Protocols, Gabriella Hancock

Human Factors and Applied Psychology Student Conference

The institution of capital punishment represents one of the most contentious issues affecting societies today; and while the practice is only implemented in 58 countries, the controversy affects the world at large as over 60% of the human population lives in nations that condone the death penalty (Hali, 2015). In the United States, people who support capital punishment believe the practice to be an effective crime deterrent for potential criminals and therefore a prospective protective measure for law abiding citizens. Moreover, advocates defend their position by forwarding the argument that executions are ‘humane’; that use of lethal injection ensures that ...


Circle Of Willis Model For Transcranial Doppler Ultrasound Training, Conner J. Beyersdorf, Ben Hage, Greg Bashford 2016 University of Nebraska-Lincoln

Circle Of Willis Model For Transcranial Doppler Ultrasound Training, Conner J. Beyersdorf, Ben Hage, Greg Bashford

UCARE Research Products

Transcranial Doppler (TCD) ultrasound is a technique involving the use of high frequency transmitters to measure intracranial blood flow. The brain is supplied by blood in an arterial anastomosis called the Circle of Willis. Using TCD ultrasound on the circle is difficult and requires practice and teaching. A functional model of the Circle of Willis could prove to be a valuable teaching tool. Through the use of AutoCAD and 3D printing software, an anatomically accurate model was created and set in gelatin phantom inside of a plastic skull. Milk was pumped through the model with a peristaltic pump to simulate ...


Detecting Heart Failure Decompensation By Measuring Transthoracic Bioimpedance In The Outpatient Setting: Rationale And Design Of The Sentinel-Hf Study, Silviu Dovancescu, Jane Saczynski, Chad Darling, Jarno Riistema, Fatima Kuniyoshi, Theo Meyer, Robert Goldberg, David McManus 2016 Philips Research

Detecting Heart Failure Decompensation By Measuring Transthoracic Bioimpedance In The Outpatient Setting: Rationale And Design Of The Sentinel-Hf Study, Silviu Dovancescu, Jane Saczynski, Chad Darling, Jarno Riistema, Fatima Kuniyoshi, Theo Meyer, Robert Goldberg, David Mcmanus

David D. McManus

BACKGROUND: Recurrent hospital admissions are common among patients admitted for acute decompensated heart failure (ADHF), but identification of patients at risk for rehospitalization remains challenging. Contemporary heart failure (HF) management programs have shown modest ability to reduce readmissions, partly because they monitor signs or symptoms of HF worsening that appear late during decompensation. Detecting early stages of HF decompensation might allow for immediate application of effective HF therapies, thereby potentially reducing HF readmissions. One of the earliest indicators of HF decompensation is intrathoracic fluid accumulation, which can be assessed using transthoracic bioimpedance.

OBJECTIVE: The SENTINEL-HF study is a prospective observational ...


Design And Analysis Of A Lift Assist Walker, Deep P. Shah 2016 California Polytechnic State University – San Luis Obispo

Design And Analysis Of A Lift Assist Walker, Deep P. Shah

Master's Theses and Project Reports

Walkers provided stability to the elderly but cannot assist a person from sitting to standing. The objective of this project is to present the design and analysis of a lift assist walker. This report discusses the design and analysis of a collapsible lift assist walker capable of lifting a patient up to 250 lbs. from seated to standing in under 10 seconds. The designed walker utilized a two stage scissor mechanism with a gas spring assisted embedded linear actuator.


Effect Of Temporal Onset Of Mechanical Loading On Tendon To Bone Healing, Determined With A Novel In-Vivo Device, Mark E. Stasiak 2016 Graduate Center, City University of New York

Effect Of Temporal Onset Of Mechanical Loading On Tendon To Bone Healing, Determined With A Novel In-Vivo Device, Mark E. Stasiak

All Graduate Works by Year: Dissertations, Theses, and Capstone Projects

Background: Exposure to tensile loading has been shown to maintain tendon/ligament homeostasis, with the tensile modulus of the tissue increasing in response to greater loading frequency, and even decreasing in the absence of load. However after injury or surgical repair the effect of tensile load is controversial, with many studies implicating mechanical loading with impaired healing. It is currently unknown when the tensile loading imparted during rehabilitation exercise, can be safely reintroduced after surgical tendon repair or ligament reconstruction, and at what time point it can most benefit the remodeling process. To investigate the effect of tensile loading protocols ...


Utilizing An Ingestible Biosensor To Assess Real-Time Medication Adherence, Peter Chai, Jose Castillo-Mancilla, Eric Buffkin, Chad Darling, Rochelle Rosen, Keith Horvath, Edwin Boudreaux, Gregory Robbins, Patricia Hibberd, Edward Boyer 2016 University of Massachusetts Medical School

Utilizing An Ingestible Biosensor To Assess Real-Time Medication Adherence, Peter Chai, Jose Castillo-Mancilla, Eric Buffkin, Chad Darling, Rochelle Rosen, Keith Horvath, Edwin Boudreaux, Gregory Robbins, Patricia Hibberd, Edward Boyer

Edwin D. Boudreaux

Medication adherence monitoring has relied largely on indirect measures of pill ingestion including patient self-report, pharmacy refills, electronically triggered pill bottles, and pill counts. Our objective is to describe an ingestible biosensor system comprising a radio-frequency identification (RFID)-tagged gelatin capsule. Once the capsule dissolves in the stomach, the RFID tag activates to transmit a unique signal to a relay device which transmits a time-stamped message to a cloud-based server that functions as a direct measure of medication adherence. We describe a constellation of mobile technologies that provide real-time direct measures of medication adherence. Optimizing connectivity, relay design, and interactivity ...


Analysis Of Vocal Fold Kinematics Using High Speed Video, Harikrishnan Unnikrishnan 2016 University of Kentucky

Analysis Of Vocal Fold Kinematics Using High Speed Video, Harikrishnan Unnikrishnan

Theses and Dissertations--Electrical and Computer Engineering

Vocal folds are the twin in-folding of the mucous membrane stretched horizontally across the larynx. They vibrate modulating the constant air flow initiated from the lungs. The pulsating pressure wave blowing through the glottis is thus the source for voiced speech production. Study of vocal fold dynamics during voicing are critical for the treatment of voice pathologies. Since the vocal folds move at 100 - 350 cycles per second, their visual inspection is currently done by strobosocopy which merges information from multiple cycles to present an apparent motion. High Speed Digital Laryngeal Imaging(HSDLI) with a temporal resolution of up to ...


Reducing Fretting Corrosion At The Femoral Neck To Taper Junction In Total Hip Arthroplasty, Andrea M. Carly, Nicholas S. Moyer, Abel S. Pietros 2016 University of Akron

Reducing Fretting Corrosion At The Femoral Neck To Taper Junction In Total Hip Arthroplasty, Andrea M. Carly, Nicholas S. Moyer, Abel S. Pietros

Honors Research Projects

Fretting corrosion due to micromotion between the femoral head and neck of hip implants is a growing concern of surgeons and patients. Debris from corrosion can lead to severe adverse effects for patients of total hip arthroplasty and reduce the lifespan of the product. Previous studies conducted by Zimmer Biomet show a connection between higher impaction force and reduced fretting corrosion and debris. This design project explored this issue and developed a training device using a current technology, a dynamic force sensor, and data analysis software for surgeons to obtain muscle memory of a 4kN strike on the head impactor ...


The Smart Hard Hat, Darcy Fyffe, Connor Langenderfer, Charlton Johns 2016 University of Akron

The Smart Hard Hat, Darcy Fyffe, Connor Langenderfer, Charlton Johns

Honors Research Projects

In a wide variety of manual labor industries, workers are often unaware that they are approaching dangerous vital thresholds until they have already overexerted themselves. According to a 2012 white paper by the Occupational Safety and Health Administration (OSHA), over 4,500 workers lose their lives, and more than 4 million are seriously injured each year. There is an immediate need to improve the safety and monitoring of manual workers to reduce the number of workplace injuries and fatalities. Millions of laborers around the globe go to work every day relying on basic safety devices, such as harnesses and steel ...


A Software Application For Cardiac-Gated Computerized Tomography Scanning, Stephen Caldwell, Trevor Engelsman 2016 University of Akron

A Software Application For Cardiac-Gated Computerized Tomography Scanning, Stephen Caldwell, Trevor Engelsman

Honors Research Projects

Computerized tomography (CT) scans are a common clinical imaging procedure used worldwide. Operating in the X-Ray spectrum, these machines rotate scanners around a stationary body in order to compile two-dimensional images into a unified three-dimensional image. With adjustment to scan frequency and intensity, internal features such as muscles, organs, and tendons can easily be viewed. However, the heart has long evaded CT use due to its near-constant motion. Recently, cardiac-gated scans have entered the market as a technique to image the heart at a specific moment in time when it is nearly still - the quiescent period. Occurring during rapid depolarization ...


Pediatric Electrical Stimulation For Limb Lengthening: A Non-Invasive Approach, Corey J. Schurko, Sofia Chinchilla, Amanda E. Pinheiro, Jacob A. Brock 2016 University of Akron

Pediatric Electrical Stimulation For Limb Lengthening: A Non-Invasive Approach, Corey J. Schurko, Sofia Chinchilla, Amanda E. Pinheiro, Jacob A. Brock

Honors Research Projects

Leg Length Discrepancy (LLD) is a problematic ailment for children as the differences in limb lengths can lead to scoliosis, hip, knee, and ankle problems, and back pain. If LLD is untreated, the symptoms will worsen as the child matures. Today LLD is corrected by using the Ilizarov Method, which uses pins that are externally attached to the broken bone for extension over time using a fixator or by using internal plates that do not require externalization. In our project we aim to use external electrical stimulation to correct the limb discrepancies. Several companies, such as Zimmer Biomet, have created ...


Hydroband: The Continuous Hydration Monitoring System, Karina E. Atkinson, Catherine P. Benedict 2016 University of Akron

Hydroband: The Continuous Hydration Monitoring System, Karina E. Atkinson, Catherine P. Benedict

Honors Research Projects

Dehydration is defined as a mild, moderate, or extreme loss of water in the body. It can result in fever, muscle cramps, headaches, dizziness, or heat stroke in athletes. Ways to determine hydration levels include analysis of the urine, blood, or sweat, body weight changes, skin elasticity tests, and increases in core temperature. Patent search, research journals, and outside studies in the health and fitness market showed that a convenient and continuous hydration monitoring system was not available. Changes in core body temperature proved to be the quickest way to measure hydration levels. The HydroBand system is geared towards athletes ...


Emlighten, Emily Mulvany 2016 University of Akron

Emlighten, Emily Mulvany

Honors Research Projects

This project is focused on creating a system to increase patient satisfaction in hospitals. My senior design team has been working hand in hand with the emergency department of Akron General to design this system called EMlighten. The goal is to create an experience for patients where they exit the hospital feeling more satisfied than they currently are. Patient satisfaction is a key performance indicator used by many hospitals to determine how much additional funding each hospital department is granted. If patients feel more satisfied, not only is that indicative of better care, but departments will receive extra funding. EMlighten ...


Assessment Of Optimized Electrode Configuration In Electrical Impedance Myography Study Using Genetic Algorithm Via Finite Element Model, Somen Baidya 2016 Georgia Southern University

Assessment Of Optimized Electrode Configuration In Electrical Impedance Myography Study Using Genetic Algorithm Via Finite Element Model, Somen Baidya

Electronic Theses & Dissertations

Electrical Impedance Myography (EIM) is a neurophysiologic technique in which high- frequency, low-intensity electrical current is applied via surface electrodes over a muscle or muscle group of interest and the resulting electrical parameters (resistance, reactance and phase) are analyzed to isolate diseased muscles from healthy ones. Beside muscle properties, some other anatomic and non-anatomic factors like muscle shape, subcutaneous fat (SF) thickness, inter-electrode distance, etc. also impact the major EIM parameters and thus affect the EIM analysis outcomes. The purpose of this study is to explore the effects of variation in some of these factors impose on EIM parameters and ...


Material Redesign Of A Lower Leg Sports Prosthesis, Alexander R. Hendricks, Matthew T. Siniawski 2015 Loyola Marymount University

Material Redesign Of A Lower Leg Sports Prosthesis, Alexander R. Hendricks, Matthew T. Siniawski

Research & Exhibition

In this research project, carbon fiber is explored as a potential replacement material for grade 5 titanium alloy in sports prosthesis. Grade 5 titanium alloy is the main structural component of current sports prosthesis, but as a material it has some key flaws. In order to make improvements in the field of sports prosthesis, carbon fiber is to be tested as a potential replacement material for titanium. Carbon fiber was chosen as it is seen as a very strong, new material and its potential to be used in various fields has been detailed by many scientists, designers, and engineers. The ...


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