Open Access. Powered by Scholars. Published by Universities.®

Systems and Integrative Engineering Commons

Open Access. Powered by Scholars. Published by Universities.®

144 Full-Text Articles 258 Authors 66,782 Downloads 49 Institutions

All Articles in Systems and Integrative Engineering

Faceted Search

144 full-text articles. Page 1 of 7.

Shape Memory Alloy Capsule Micropump For Drug Delivery Applications, Youssef Mohamed Kotb 2024 American University in Cairo

Shape Memory Alloy Capsule Micropump For Drug Delivery Applications, Youssef Mohamed Kotb

Theses and Dissertations

Implantable drug delivery devices have many benefits over traditional drug administration techniques and have attracted a lot of attention in recent years. By delivering the medication directly to the tissue, they enable the use of larger localized concentrations, enhancing the efficacy of the treatment. Passive-release drug delivery systems, one of the various ways to provide medication, are great inventions. However, they cannot dispense the medication on demand since they are nonprogrammable. Therefore, active actuators are more advantageous in delivery applications. Smart material actuators, however, have greatly increased in popularity for manufacturing wearable and implantable micropumps due to their high energy …


Computational Predictions Of Heart Failure Drug Effects On Cardiac Fibrosis, Aaron Gardner 2024 University of Arkansas, Fayetteville

Computational Predictions Of Heart Failure Drug Effects On Cardiac Fibrosis, Aaron Gardner

Chemical Engineering Undergraduate Honors Theses

The extracellular matrix is a complex system surrounding cells that is crucial to all of the cardiovascular system’s functions. Fibrosis is an excessive accumulation (scarring) of the extracellular matrix. Fibrosis is typically a negative event, and the scarring must be reduced in the heart in order to maintain its functionality. Due to this, simulations are run using the software “Netflux” in order to determine the effects of different heart failure drugs on cardiac fibrosis. The drugs that were simulated were an ACE Inhibitor, BAR Beta Blocker, ARB Blocker, and Entresto. These drugs were simulated over 50 hours at three different …


Secured Blockchain And Fractional Discrete Cosine Transform-Based Framework For Medical Images, Abhay Kumar Yadav, Virendra P. Vishwakarma 2024 Guru Gobind Singh Indraprastha University, New Delhi

Secured Blockchain And Fractional Discrete Cosine Transform-Based Framework For Medical Images, Abhay Kumar Yadav, Virendra P. Vishwakarma

Makara Journal of Technology

Images can store large amounts of data and are useful for transmitting large amounts of information across different geographical locations using different cloud services. This data sharing increases the chances of cyber-attacks on digital images. Blockchain has properties that enable it to work as a solution to this problem, providing enhanced security and unchangeable storage. However, image size poses a challenge in image storage, as it increases the related storage cost. Compressing images using fractional discrete cosine transform (fctDCT) reduces the amount of data required to express an image securely. This paper presents a novel framework for securely storing and …


Mathematical Modeling For Dental Decay Prevention In Children And Adolescents, Mahdiyeh Soltaninejad 2024 Kennesaw State University

Mathematical Modeling For Dental Decay Prevention In Children And Adolescents, Mahdiyeh Soltaninejad

Dissertations

The high prevalence of dental caries among children and adolescents, especially those from lower socio-economic backgrounds, is a significant nationwide health concern. Early prevention, such as dental sealants and fluoride varnish (FV), is essential, but access to this care remains limited and disparate. In this research, a national dataset is utilized to assess sealants' reach and effectiveness in preventing tooth decay, particularly focusing on 2nd molars that emerge during early adolescence, a current gap in the knowledge base. FV is recommended to be delivered during medical well-child visits to children who are not seeing a dentist. Challenges and facilitators in …


Redesign Of Robotic Walking Training Device To Involve Zero Gravity Capabilities And Daily Activities, Chad Ballard 2024 University of Texas at Tyler

Redesign Of Robotic Walking Training Device To Involve Zero Gravity Capabilities And Daily Activities, Chad Ballard

Mechanical Engineering Theses

Many patients struggle with disabilities that hinder their ability to walk. This project aimed to create a leg assembly capable of variable gravity so that it could be combined with a Robotic Walking Training Device, and lead to better rehabilitation options for patients. This was accomplished by deriving equations of joint torque, creating circuit diagrams for Arduino systems, modeling leg assemblies in CAD, and finally combining it to create a working small-scale prototype. The result of the prototype testing showed accurate movement on each joint, especially the ankle and knee segments, to create virtual zero gravity. In addition to this, …


Emotion Recognition As A Novel Indicator For Assessing Brain Health: A Machine Learning Approach, Nayarah Shabir, Parveen Lehana 2024 University of Jammu, India

Emotion Recognition As A Novel Indicator For Assessing Brain Health: A Machine Learning Approach, Nayarah Shabir, Parveen Lehana

Research Symposium

Background: Emotion is being referred to as a person’s mental state, since it relates to their ideas, feelings, and actions. There is a lot of evidence that health affects the emotion. Therefore, the nature of emotions ought to reveal the health of a person. The emotions are represented by facial expressions controlled by muscular motor actions. Brain health may affect the working of the muscles leading to the emotional changes extracted from the facial images.

Methods: A dataset of facial images annotated with matching emotion labels is the first step in using convolutional neural networks (CNNs) for facial …


Bridging Language Barriers In Clinical Screening: Leveraging Large Language Models (Llms) To Generate Bilingual Screening Surveys For Patients With Limited English Proficiency (Plep), Tyler VanDyk 2024 University of Vermont

Bridging Language Barriers In Clinical Screening: Leveraging Large Language Models (Llms) To Generate Bilingual Screening Surveys For Patients With Limited English Proficiency (Plep), Tyler Vandyk

Family Medicine Clerkship Student Projects

This study addresses the critical need for accessible clinical screening in communities with a high incidence of Patients with Limited English Proficiency (PLEP). Recognizing the limitations of existing interpreter services and the scarcity of validated translations for standard clinical surveys like PHQ-9 and GAD-7, we developed a novel approach leveraging Large Language Models (LLMs). Our method utilizes GPT-4 to create bilingual versions of these surveys, which are then formatted into printable PDFs via a Python script and LuaLaTeX compiler. The resulting surveys, validated for translation accuracy and cultural competency, are made accessible through a Google repository. Preliminary results demonstrate that …


Analysis And Characterization Of Embroidered Textile Strain Sensors For Use In Wearable Mechatronic Devices, Jose Guillermo Colli Alfaro 2023 Western University

Analysis And Characterization Of Embroidered Textile Strain Sensors For Use In Wearable Mechatronic Devices, Jose Guillermo Colli Alfaro

Electronic Thesis and Dissertation Repository

Stroke and musculoskeletal disorders affect hundreds of millions of people around the world. To aid in the recovery process of people affected by these conditions, the use of wearable mechatronic devices has been proposed during traditional rehabilitation therapies. However, factor such as rigidity, increased weight, and overall bulkiness have hindered the adoption of these devices in a clinical setting. Therefore, alternative solutions in the form of soft wearable mechatronic devices have been proposed recently. This is due to these devices being lightweight and comfortable, and compliant, which makes them easier to conform to the human body. To achieve such compliance, …


Enhancing Human Key Point Identification: A Comparative Study Of High-Resolution Vicon Dataset And Coco Dataset Using Bpnet, Bibash Lama 2023 Grand Valley State University

Enhancing Human Key Point Identification: A Comparative Study Of High-Resolution Vicon Dataset And Coco Dataset Using Bpnet, Bibash Lama

Masters Theses

Accurately identifying human key points is crucial for various applications, including activity recognition, pose estimation, and gait analysis. This study presents a high-resolution dataset created using the VICON motion capture system and three differently oriented 2D cameras, that can be used to train different neural networks for estimating the 2D key joint positions of the person from the 2D images or videos. The participants in the study included 25 healthy adults (17 males and 8 females) performing normal gait movements for about 2 to 3 seconds. The VICON system captured 3D ground truth data, while the three 2D cameras collected …


Soil Respiration Measurements Reveal High Retention Of Organic Carbon From Corn Residue Derived High-Lignin Fermentation Byproduct Enabling Sustainable Lignocellulosic Biofuel Production, Michelle Sun Wang 2023 Dartmouth College

Soil Respiration Measurements Reveal High Retention Of Organic Carbon From Corn Residue Derived High-Lignin Fermentation Byproduct Enabling Sustainable Lignocellulosic Biofuel Production, Michelle Sun Wang

Dartmouth College Master’s Theses

While 2G biofuel production can utilize non-edible, lignocellulosic feedstocks such as agricultural residues to produce liquid fuel, harvesting crop residues is unsustainable without careful management of the soil underneath. By harvesting a fraction of the crop residues left in the field after harvest, soil health can diminish and critically, the soil organic carbon (SOC) stored in agricultural fields can decrease. Currently, in the most popular 2G process models published, the issue of soil degradation remains unresolved with residue harvest strategies receiving considerable attention in the literature and other SOC management strategies receiving far less. Specifically, the strategy of returning the …


Multichannel Modulation Of Depolarizing And Repolarizing Ion Currents Increases The Positive Rate-Dependent Action Potential Prolongation, Candido Cabo 2023 CUNY New York City College of Technology

Multichannel Modulation Of Depolarizing And Repolarizing Ion Currents Increases The Positive Rate-Dependent Action Potential Prolongation, Candido Cabo

Publications and Research

Prolongation of the action potential duration (APD) could prevent reentrant arrhythmias if prolongation occurs at the fast excitation rates of tachycardia with minimal prolongation at slow excitation rates (i.e., if prolongation is positive rate-dependent). APD prolongation by current anti-arrhythmic agents is either reverse (larger APD prolongation at slow rates than at fast rates) or neutral (similar APD prolongation at slow and fast rates), which may not result in an effective anti-arrhythmic action. In this report we show that, in computer models of the human ventricular action potential, the combined modulation of both depolarizing and repolarizing ion currents results in a …


An Epileptic Seizure Detection Method From Eeg Signals Based On A Classifier-Driven Feature Reduction Technique, Raymond N. Kamel 2023 The American University in Cairo AUC

An Epileptic Seizure Detection Method From Eeg Signals Based On A Classifier-Driven Feature Reduction Technique, Raymond N. Kamel

Theses and Dissertations

Epileptic seizure detection can improve the quality of life of epileptic patients, allow for more accurate medication, and minimize the risk of sudden unexpected death in epilepsy (SUDEP). This thesis work aims to develop a robust and stable algorithm for epileptic seizure detection through the classification of EEG signals. To achieve this aim, a methodology is proposed to develop a classifier that can differentiate between the healthy (normal), interictal, and ictal states of EEG signals, while maximizing the classification accuracy and minimizing the computational redundancy. The main pillar upon which this methodology is designed is using a problem-specific classifier-driven feature …


On The Pursuit Of Developer Happiness: Webcam-Based Eye Tracking And Affect Recognition In The Ide, Tamsin Rogers 2023 Colby College

On The Pursuit Of Developer Happiness: Webcam-Based Eye Tracking And Affect Recognition In The Ide, Tamsin Rogers

Honors Theses

Recent research highlights the viability of webcam-based eye tracking as a low-cost alternative to dedicated remote eye trackers. Simultaneously, research shows the importance of understanding emotions of software developers, where it was found that emotions have significant effects on productivity, code quality, and team dynamics. In this paper, we present our work towards an integrated eye-tracking and affect recognition tool for use during software development. This combined approach could enhance our understanding of software development by combining information about the code developers are looking at, along with the emotions they experience. The presented tool utilizes an unmodified webcam to capture …


Design And Fabrication Of A Force-Displacement Control Mechanism For Bone-Surgical Tool Testing, Kenneth Nwagu 2023 Georgia Southern University

Design And Fabrication Of A Force-Displacement Control Mechanism For Bone-Surgical Tool Testing, Kenneth Nwagu

Electronic Theses and Dissertations

This project focuses on the design and fabrication of an experimental setup for orthopedic-tool testing, tailored for a surgical instrumentation company. The multifaceted project encompasses a literature review, conceptual design, prototyping, and rigorous testing, resulting in a versatile control system capable of assessing various orthopedic tools, including bone drills, saws, burrs, and power handpieces.

Orthopedic surgical procedures (which include cutting and/or drilling into bone) often need to be performed on bones for faster recovery. The drilling and cutting process can cause an increase in temperature at the cutting site which can cause bone necrosis. The tools also need to be …


Seeing The Big Picture: System Architecture Trends In Endoscopy And Led-Based Hyperspectral Subsystem Intergration, Craig M. Browning 2022 University of South Alabama

Seeing The Big Picture: System Architecture Trends In Endoscopy And Led-Based Hyperspectral Subsystem Intergration, Craig M. Browning

<strong> Theses and Dissertations </strong>

Early-stage colorectal lesions remain difficult to detect. Early development of neoplasia tends to be small (less than 10 mm) and flat and difficult to distinguish from surrounding mucosa. Additionally, optical diagnosis of neoplasia as benign or malignant is problematic. Low rates of detection of these lesions allow for continued growth in the colorectum and increased risk of cancer formation. Therefore, it is crucial to detect neoplasia and other non-neoplastic lesions to determine risk and guide future treatment. Technology for detection needs to enhance contrast of subtle tissue differences in the colorectum and track multiple biomarkers simultaneously. This work implements one …


Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones 2022 California Polytechnic State University, San Luis Obispo

Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones

Biomedical Engineering: Graduate Reports and Projects

This paper describes the design, manufacturing, and testing of a novel controllable hypoxic incubator with fully functional oxygen gas control and temperature control in a humid environment. On the current market, a majority of the few hypoxic incubators use pre-mixed gas that does not offer precise control over gas concentration. The objective for this project was to create a chamber that allows the user to set the O2 concentration to varying set points of % O2 while maintaining the chamber at a constant body temperature, CO2 level, humidity, and sterility. To start the project, multiple concepts were developed for the …


Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones 2022 California Polytechnic State University, San Luis Obispo

Hypoxic Incubation Chamber, Simone Lisette Helfrich, Makenzie Nicole Jones

Master's Theses

This paper describes the design, manufacturing, and testing of a novel controllable hypoxic incubator with fully functional oxygen gas control and temperature control in a humid environment. On the current market, a majority of the few hypoxic incubators use pre-mixed gas that does not offer precise control over gas concentration. The objective for this project was to create a chamber that allows the user to set the O2 concentration to varying set points of % O2 while maintaining the chamber at a constant body temperature, CO2 level, humidity, and sterility. To start the project, multiple concepts were developed for the …


Using In Vitro, In Silico, And In-Classroom Techniques To Address The Gender Data Gap In Health Care, Kelsey Watts 2022 Clemson University

Using In Vitro, In Silico, And In-Classroom Techniques To Address The Gender Data Gap In Health Care, Kelsey Watts

All Dissertations

Cardiovascular diseases (CVDs) are the leading cause of death worldwide in males (XY) and females (XX). Prior to menopause, females have a relative protection against serious cardiac pathologies compared to age-matched males. This phenomenon is widely attributed to the ovarian hormone estrogen. Unfortunately, hormone replacement therapy to maintain estrogen levels in postmenopausal females has overall adverse effects, and it is not recommended for long-term use or as a preventative measure for eCVDs. A major driver of CVDs, specifically heart failure, is cardiac fibrosis: the continued buildup of scar tissue that reduces the heart’s ability to pump. There are currently no …


Development Of An Equation To Correlate Brite Tank Temperature And Pressure To Beverage Carbonation Concentration, Devyn Meyer 2022 University of Arkansas, Fayetteville

Development Of An Equation To Correlate Brite Tank Temperature And Pressure To Beverage Carbonation Concentration, Devyn Meyer

Biological and Agricultural Engineering Undergraduate Honors Theses

The Carbo Rock-It™ is an invention created to carbonate beverages at craft breweries. One of the Carbo Rock-It’s main features is that it does not add a significant volume of undissolved gas bubbles to the brite tank in which the beverage is carbonated. This may allow temperature and pressure readings from the brite tank to be used to determine the concentration of dissolved carbon dioxide in the beverage continuously in real time. This eliminates the need for manual samplings, which could save breweries time and allow for more controlled, accurate carbonation. The goal of this project was to develop an …


Insole Fall Prevention Device, Nick M. Hughes, Andrew M. Slaboda 2022 California Polytechnic State University, San Luis Obispo

Insole Fall Prevention Device, Nick M. Hughes, Andrew M. Slaboda

Biomedical Engineering

Falls among the aging population occur every single day, with 1 in every 5 resulting in some injury and 300,000 hospitalized every year with a hip fracture [1]. The most popular and effective way to mitigate these falls is through physical therapist intervention. However, with the increased popularity in telerehab, many patients at risk for falls cannot accurately convey their gait tendencies to their physical therapists from the comfort of their home or while not in direct contact with the PT. A device like an insole, implanted with force sensors, which measures different parts of a patient’s foot, could convey …


Digital Commons powered by bepress