Clinically Relevant Intronic Splicing Enhancer Mutation In Myelin Proteolipid Protein Leads To Progressive Microglia And Astrocyte Activation In White And Gray Matter Regions Of The Brain,
2013
University of Kentucky
Clinically Relevant Intronic Splicing Enhancer Mutation In Myelin Proteolipid Protein Leads To Progressive Microglia And Astrocyte Activation In White And Gray Matter Regions Of The Brain, Adam D. Bachstetter, Scott J. Webster, Linda J. Van Eldik, Franca Cambi
Sanders-Brown Center on Aging Faculty Publications
INTRODUCTION: Mutations in proteolipid protein (PLP), the most abundant myelin protein in the CNS, cause the X-linked dysmyelinating leukodystrophies, Pelizaeus-Merzbacher disease (PMD) and spastic paraplegia type 2 (SPG2). Point mutations, deletion, and duplication of the PLP1 gene cause PMD/SPG2 with varying clinical presentation. Deletion of an intronic splicing enhancer (ISEdel) within intron 3 of the PLP1 gene is associated with a mild form of PMD. Clinical and preclinical studies have indicated that mutations in myelin proteins, including PLP, can induce neuroinflammation, but the temporal and spatial onset of the reactive glia response in a clinically relevant mild form of PMD …
'To Change Is To Learn And To Learn Is To Change',
2013
University of Central Florida
'To Change Is To Learn And To Learn Is To Change', Bob Porter
UCF Forum
“To change is to learn and to learn is to change.” That was often the advice given to me by my mentor in life, Lew Treen, a war veteran, semi-pro baseball player, high school principal and coach.
Primetimes Newsletter, Winter 2013,
2013
Coastal Carolina University
Primetimes Newsletter, Winter 2013, Office Of Lifespan Studies
PrimeTimes Newsletter
PrimeTimes is the newsletter of the Office of Lifespan Studies in the College of Science at Coastal Carolina University.
Effects Of Parental Divorce And Childhood Paternal And Maternal Attachment On Religious Outcomes In Young Adulthood,
2013
University of Texas Permian Basin
Effects Of Parental Divorce And Childhood Paternal And Maternal Attachment On Religious Outcomes In Young Adulthood, Lyndsay A. Freeman
Graduate Theses
This study investigated the relationship between 72 respondents’ parental marriage status and childhood parental attachment on religious outcomes in young adulthood. It partly replicated a study by Zhai et al. (2007) with several notable differences, such as using recent data as opposed to archived data and examining both maternal and paternal attachments separately in light of the compensation hypothesis of religious attachment theory. An online survey was used to gather data. Chi-square tests revealed there were significantly more participants with insecure paternal attachments from families with divorced parents than from traditional families. Also, participants with insecure paternal attachments switched religious …
Still Siblings: The Perceived Importance Of Sibling Relationships For Foster Children,
2013
Western Michigan University
Still Siblings: The Perceived Importance Of Sibling Relationships For Foster Children, Jessica A. Church
Masters Theses
This research was conducted to answer the question “Do children who are perceived to have strong relationships with siblings and more access to their siblings have fewer problems adjusting to their foster care placement as observed by child welfare professionals?” This qualitative research project was completed through semi-structured interviews with professionals who work with children in foster care in a variety of ways (and may have worked with children in more than one way during their career in child welfare), such as foster care workers, counselors, and sibling visitation supervisors. The snowball sampling method was used in this research. These …
Reciprocity And Social Capital In Sibling Relationships Of People With Disabilities,
2013
University of Massachusetts Boston
Reciprocity And Social Capital In Sibling Relationships Of People With Disabilities, John Kramer, Allison Hall, Tamar Heller
All Institute for Community Inclusion Publications
Sibling relationships are some of the longest-lasting relationships people experience, providing ample opportunities to build connections across the lifespan. For siblings and people with intellectual and developmental disabilities (I/DD), these connections take on an increased significance as their families age and parents can no longer provide care. This paper presents findings from a qualitative study that addresses the question, “How do siblings support each other after parents no longer can provide care to the person with I/DD?” Findings in this study suggest that siblings with and without disabilities experience reciprocity as a transitive exchange, which occurs through the creation of …
Juvenile Court Officers’ Perceptions Of Innovation Adoption; What Personal And Contextual Factors Make A Difference In Levels Of Adoption? An Exploratory Mixed-Method Study.,
2013
University of Nebraska-Lincoln
Juvenile Court Officers’ Perceptions Of Innovation Adoption; What Personal And Contextual Factors Make A Difference In Levels Of Adoption? An Exploratory Mixed-Method Study., Brenda Jean Moran
College of Education and Human Sciences: Dissertations, Theses, and Student Research
This exploratory research examined levels of innovation adoption among Juvenile Court Officers (JCOs) in a Midwestern state. The researcher applied Everett M. Rogers’ Diffusion of Innovation model as the study’s framework. According to Rogers (2003), innovation is “an idea, practice or object that is perceived as new by an individual or other unit of adoption” (p. 475). The study sought to determine the extent that demographic and work-life variables such as gender, office location, caseload, years of service, personality/temperament and employee engagement contributed to levels of innovation adoption by JCOs. This study examined the characteristics of individuals and contexts in …
Witnessing Inter-Parental Violence At Home: Adolescents And School Achievement,
2013
University of Nebraska-Lincoln
Witnessing Inter-Parental Violence At Home: Adolescents And School Achievement, Renita Dawn Robinson-Tyrance
Department of Sociology: Dissertations, Theses, and Student Research
Children’s exposure to violence is a serious social problem, but little is known about the educational implications for adolescents witnessing violence between parents. This study uses social learning theory (SLT) to examine the relationship between high school-aged adolescent students who witness parental intimate partner violence (IPV) and academic performance demonstrated by their grade point averages (GPA). A secondary analysis of data collected from the survey of 1,132 adolescent students in a medium sized, suburban/rural city was conducted. Of the respondents, 83% of the students did not witness parental IPV between parents. Students witnessing the most parental IPV had the lowest …
Evaluating The Smart Steps For Stepfamilies: Embrace The Journey Program, A Hierarchical Examination,
2013
Utah State University
Evaluating The Smart Steps For Stepfamilies: Embrace The Journey Program, A Hierarchical Examination, Katie L. Reck
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Over the past decade, relationship education has grown as a means of enhancing couple relations. This study examines the experiences of 2,828 ethnically diverse and low-income adults who participated in the Smart Steps for Stepfamilies: Embrace the Journey program, a 12-hour stepfamily education program. Self-report measures of relationship quality, couple commitment, and relationship instability were gathered prior to and immediately after the Smart Steps intervention as well as six weeks, six months, and one year post-program. Results suggest that stepfamily participants experienced increases in relationship quality; however, these increases reduced to near pre-program levels one year after the programs completion. …
The Influence Of Family Dynamics On Contraceptive Use In Madagascar And The Ensuing Impact On Family Well-Being,
2013
Andrews University
The Influence Of Family Dynamics On Contraceptive Use In Madagascar And The Ensuing Impact On Family Well-Being, Joel Zafitandra Hajason, Kayla Piña, Joel L. Raveloharimisy
Faculty Publications
While studies have shown a relationship between family dynamics and contraceptive use and between contraceptive use and family well-being, no empirical study has been conducted to test whether a relationship exists between family influence on contraceptive use and family wellbeing. The objective of this study is to explore whether there is such a relationship between family influence on contraceptive use and family well-being.
Investigating Potential Factors That Influence Recruitment For Parenting Skills Classes,
2013
University of Nevada, Las Vegas
Investigating Potential Factors That Influence Recruitment For Parenting Skills Classes, Rachel Elizabeth Davis
UNLV Theses, Dissertations, Professional Papers, and Capstones
Juvenile delinquency and child maltreatment are prevalent in the U.S., particularly among ethnic minority children. Although parent skills training is effective in preventing these problems, recruitment and retention rates of parents from ethnic, racial, and socioeconomic minority groups are less than satisfactory. In a qualitative study of 13 high-risk African American mothers, Davis (2009) investigated the deterrents to recruitment and participation for parent skills training programs. The resulting theory, the Mothers Shouldn't Need Help Script, explicates the relationship between the beliefs reported by these mothers and participation in parenting skills classes. To build on these findings, the overarching purpose of …
What Works In Suicide Bereavement: What Helps And What Hurts?,
2013
University of Nevada, Las Vegas
What Works In Suicide Bereavement: What Helps And What Hurts?, Quintin Hunt
UNLV Theses, Dissertations, Professional Papers, and Capstones
Suicide is one of the most painful grief experiences that any family may experience. The suicide bereavement literature, though small, is replete with research that shows family and systemic impacts of suicide. The literature also includes constant calls for family- and systemic-based intervention as every part of society is impacted. Research in the field of marriage and family therapy, however, has ignored suicide and suicide bereavement almost entirely. The purpose of this qualitative study is to develop a more thorough understand of the grief that survivors of suicide experience and to systemically understand what helps and hurts the grieving process. …
Perceptions And Definition Of Infidelity: A Multimethod Study,
2013
University of Nevada, Las Vegas
Perceptions And Definition Of Infidelity: A Multimethod Study, Sarah Schonian
UNLV Theses, Dissertations, Professional Papers, and Capstones
Most couples in committed relationships have implicit or explicit rules regarding infidelity. However, not all partners view infidelity in the same way, and the discrepancy in opinions can lead to problems in the relationship and can complicate the healing process. The purpose of this study was to better understand how people define infidelity and the variables that influence perceptions about infidelity. A mutlimethod design was used to collect quantitative and qualitative data on participants' perceptions and definitions of infidelity. Quantitative data was collected through participants' answers to questions on a scale about perceptions of potentially unfaithful behaviors that was developed …
The Effect Of Marriage On Stage At Diagnosis And Survival In Women With Cervical Cancer,
2013
University of Nevada, Las Vegas
The Effect Of Marriage On Stage At Diagnosis And Survival In Women With Cervical Cancer, Sanae El Ibrahimi
UNLV Theses, Dissertations, Professional Papers, and Capstones
Marriage is associated with improved health outcomes for many conditions. Married persons enjoy financial stability, social and emotional support, and tend to have better control of health risk behaviors compared to the unmarried. The marriage scene is changing continuously. Americans are marrying less or delaying the engagement to an older age. They are divorcing more, they choose cohabitation as an alternative to marriage, or engage in premarital relationships. As a consequence, barely half of Americans were married in 2011 compared to close to three quarters of Americans were married in the sixties. With the increase of the unmarried population - …
Adolescent Self-Disclosure And Father Involvement Transactions Across Early To Midadolescence,
2013
Brigham Young University - Provo
Adolescent Self-Disclosure And Father Involvement Transactions Across Early To Midadolescence, Stephanie Blickfeldt
Theses and Dissertations
This study investigates the transactional relationship between father involvement and adolescent self-disclosure from early to midadolescence. Four hundred and ninety-six adolescents reported on their general self-disclosure to fathers, and mothers reported on father involvement behaviors and maternal involvement behaviors at ages 11, 13, and 15. Results from a longitudinal cross-lagged model indicated a unidirectional relationship from father involvement to child self-disclosure in both early and midadolescence, and a transactional relationship from adolescent self-disclosure to father involvement in early adolescence. A multiple group analysis by gender revealed that both unidirectional and transactional relationships were significant for boys only. Future research efforts …
Let's Set Aside Differences – Not Just During This Season, But All Year,
2013
University of Central Florida
Let's Set Aside Differences – Not Just During This Season, But All Year, Erin O'Flaherty
UCF Forum
‘Tis the season, the season of giving—whether giving thanks, praises, spare change, an extra tip or bonus. You name it, and it’s officially “the season” for it.
The Most Wonderful Time Of The Year,
2013
University of Central Florida
The Most Wonderful Time Of The Year, Rebekah Mccloud
UCF Forum
When is the most wonderful time of the year? December — right? — despite the many people and things that try to blur the calendar.
The Primacy Of Context: An Exploration Into The Causes Of Food Insecurity In Kitere, Kenya.,
2013
SIT Graduate Institute
The Primacy Of Context: An Exploration Into The Causes Of Food Insecurity In Kitere, Kenya., William O. Aludo
Capstone Collection
The purpose of this study was to explore the specific reasons why households in Kitere village, Kenya experience persistent food insecurity every year while the region enjoys the advantage of two planting/harvest seasons in a year. Kitere village lies within the lakeside region of Nyanza Province in Kenya, generally considered to be one of the more agriculturally productive parts of the country. The Participatory Rural Appraisal method was employed to gather qualitative data on the causes of food insecurity in Kitere village. The data sources were focus groups and a self-administered, one-time survey of random and non-random samples of key …
Solving The ‘Mystery’ Of Cranberry Sauce At The Holiday For All Americans,
2013
University of Central Florida
Solving The ‘Mystery’ Of Cranberry Sauce At The Holiday For All Americans, Maritza Martinez
UCF Forum
About this time of year the past several years, my husband can’t help but comment on the total departure from the “traditional” Thanksgiving feast available at our family’s gathering.
Snap Use Increased Slightly In 2012,
2013
University of New Hampshire, Durham
Snap Use Increased Slightly In 2012, Jess Carson
Carsey Publications
This brief uses data from the American Community Survey to examine rates of Supplemental Nutrition Assistance Program (SNAP) receipt in 2012, track changes since the onset of the recession, and monitor receipt by region and place type. It also explores changes in SNAP receipt among households that may be at particular risk for food insecurity and considers rates among some less traditionally at-risk populations, exploring changes in their rates of receipt over time.
Author Jessica Carson writes that reports of SNAP receipt in 2012 increased among populations at particular risk for food insecurity, including households with children, seniors, the poor, …
